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BIOINFORMATICS Vol. 19 no. 5 2003, pages 618624

Vol. 19 no. 5 2003, pages 618­624
DOI: 10.1093/bioinformatics/btg065
How Bayes tests of molecular phylogenies
compare with frequentist approaches
St´ephane Aris-Brosou
Department of Biology, University College London, Darwin Building, Gower Street,
London WC1E 6BT, UK
Received on May 27, 2002; revised on September 17, 2002; November 8, 2002; accepted on November
26, 2002
Motivation: The desire to compare molecular phylogenies
has stimulated the design of numerous tests. Most of these
tests are formulated in a frequentist framework, and it is
not known how they compare with Bayes procedures. I
propose here two new Bayes tests that either compare
pairs of trees (Bayes hypothesis test, BHT), or test each
tree against an average of the trees included in the
analysis (Bayes significance test, BST).
Results: The algorithm, based on a standard Metropolis­


Source: Aris-Brosou, Stéphane - Department of Biology, University of Ottawa


Collections: Biology and Medicine