Summary: The genome sequence of T. parva shows
remarkable differences from the other apicom-
plexan genomes sequenced to date. It provides
significant improvements in our understanding
of the metabolic capabilities of T. parva and a
foundation for studying parasite-induced host
cell transformation and constitutes a critical
knowledge base for a pathogen of significance
to agriculture in Africa. Mining of sequence
data has already proved useful in the search for
candidate vaccine antigens (3).
References and Notes
1. R. A. I. Norval, B. D. Perry, A. S. Young, The Epi-
demiology of Theileriosis in Africa (Academic Press,
London, 1992), p. 481.
2. A. A. Escalante, F. J. Ayala, Proc. Natl. Acad. Sci.
U.S.A. 92, 5793 (1995).
3. S. P. Graham et al., in preparation.
4. A. Pain et al., Science 309, 131 (2005).
5. Materials and methods are available as supporting