Summary: Inactivation of Semicircular Canals Causes Adaptive Increases
in Otolith-Driven Tilt Responses
DORA E. ANGELAKI,1
SHAWN D. NEWLANDS,2
AND J. DAVID DICKMAN3
1
Department of Neurobiology, Washington University School of Medicine, St. Louis, Missouri 63110; 2
Department of
Otolaryngology, University of Texas Medical Branch, Galveston, Texas 77550; and 3
Department of Research, Central
Institute for the Deaf, St. Louis, Missouri 63110
Received 18 September 2001; accepted in final form 31 October 2001
Angelaki, Dora E., Shawn D. Newlands, and J. David Dickman.
Inactivation of semicircular canals causes adaptive increases in oto-
lith-driven tilt responses. J Neurophysiol 87: 1635­1640, 2002;
10.1152/jn.00775.2001. Growing experimental and theoretical evi-
dence suggests a functional synergy in the processing of otolith and
semicircular canal signals for the generation of the vestibulo-ocular
reflexes (VORs). In this study we have further tested this functional
interaction by quantifying the adaptive changes in the otolith-ocular

Source: Angelaki, Dora - Department of Anatomy and Neurobiology, Washington University in St. Louis
Dickman, J. David - Department of Anatomy and Neurobiology, Washington University in St. Louis

Collections: Biology and Medicine