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Nucleic Acids Research, 2007, 16 doi:10.1093/nar/gkm949
 

Summary: Nucleic Acids Research, 2007, 16
doi:10.1093/nar/gkm949
TranspoGene and microTranspoGene: transposed
elements influence on the transcriptome of seven
vertebrates and invertebrates
Asaf Levy, Noa Sela and Gil Ast*
Department of Molecular Genetics and Biochemistry, Tel-Aviv University Medical School, Tel Aviv 69978, Israel
Received September 6, 2007; Revised October 14, 2007; Accepted October 15, 2007
ABSTRACT
Transposed elements (TEs) are mobile genetic
sequences. During the evolution of eukaryotes
TEs were inserted into active protein-coding genes,
affecting gene structure, expression and splicing
patterns, and protein sequences. Genomic inser-
tions of TEs also led to creation and expression of
new functional non-coding RNAs such as micro-
RNAs. We have constructed the TranspoGene
database, which covers TEs located inside protein-
coding genes of seven species: human, mouse,
chicken, zebrafish, fruit fly, nematode and sea

  

Source: Ast, Gil - Department of Molecular Genetics and Biochemistry, Tel Aviv University

 

Collections: Biology and Medicine