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A miniature robot that autonomously optimizes and maintains extracellular neural action potential recordings
 

Summary: A miniature robot that autonomously optimizes and
maintains extracellular neural action potential recordings
Edward A. Branchaud, Jorge G. Cham, Zoran Nenadic,
and Joel W. Burdick
Richard A. Andersen
Division of Engineering and Applied Science Division of Biology
California Institute of Technology California Institute of Technology
Pasadena, CA 91125 Pasadena, CA 91125
eddie@caltech.edu
Abstract This paper describes a novel miniature robot
that can autonomously position recording electrodes inside
cortical tissue to isolate and maintain optimal extracellular
action potential recordings. The system consists of a novel
motorized miniature recording microdrive and a control
algorithm. The microdrive was designed for semi-chronic
operation and can independently position four electrodes with
micron precision over a 5mm range using small (3mm
diameter) piezoelectric linear actuators. The autonomous
positioning algorithm is designed to detect, align and cluster
action potentials, and then command the microdrive to

  

Source: Andersen, Richard - Division of Biology, California Institute of Technology

 

Collections: Biology and Medicine