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Summary: Downstream class switching leads to IgE antibody
production by B lymphocytes lacking IgM
switch regions
Tingting Zhanga,b,c,d
, Andrew Franklina,b,c,d
, Cristian Boboilaa,b,c,d
, Amy McQuaya,b,c,d
, Michael P. Gallaghera,b,c,d
,
John P. Manisb,e
, Ahmed Amine Khamlichif
, and Frederick W. Alta,b,c,d,1
a
Department of Genetics, Harvard Medical School, Boston, MA 02115; b
the Children's Hospital; c
Immune Disease Institute; d
Howard Hughes Medical Institute;
e
Department of Pathology, Harvard Medical School, Boston, MA 02115; and f
Centre National de la Recherche Scientifique UMR 5089-IPBS, Université de
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