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BioMed Central Page 1 of 7

Summary: BioMed Central
Page 1 of 7
(page number not for citation purposes)
Biology Direct
Open AccessDiscovery notes
Transduplication resulted in the incorporation of two
protein-coding sequences into the Turmoil-1 transposable element
of C. elegans
Noa Sela1, Adi Stern2, Wojciech Makalowski3, Tal Pupko2 and Gil Ast*1
Address: 1Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel,
2Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel and 3Institute
of Bioinformatics, Faculty of Medicine, University of Muenster, Muenster D-48149, Germany
Email: Noa Sela - noasela@post.tau.ac.il; Adi Stern - sternadi@post.tau.ac.il; Wojciech Makalowski - wojmak@uni-muenster.de;
Tal Pupko - talp@tauex.tau.ac.il; Gil Ast* - gilast@post.tau.ac.il
* Corresponding author
: Transposable elements may acquire unrelated gene fragments into their sequences in a process
called transduplication. Transduplication of protein-coding genes is common in plants, but is
unknown of in animals. Here, we report that the Turmoil-1 transposable element in C. elegans has
incorporated two protein-coding sequences into its inverted terminal repeat (ITR) sequences. The


Source: Ast, Gil - Department of Molecular Genetics and Biochemistry, Tel Aviv University
Pupko, Tal - Department of Cell Research and Immunology, Tel Aviv University


Collections: Biology and Medicine