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An Overview of Systems Biology Rka Albert1,2
 

Summary: Chapter 1
An Overview of Systems Biology
Réka Albert1,2
, Sarah M. Assmann3
1
Department of Physics, The Pennsylvania State University, University Park, PA 16802
2
Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park,
PA 16802
3
Department of Biology, The Pennsylvania State University, University Park, PA 16802
Keywords: systems biology, molecular networks, interactome, network inference, graph
analysis, dynamic modeling
Abstract
This chapter provides an overview of three crucial aspects of systems biology: constructing
biological networks, analyzing and modeling the structure of biological networks, and
modeling the dynamics of biological networks. We describe the types of intracellular
networks most often studied, and the "omic" information available to synthesize these
networks, with a special focus on plant biology. We review the computational methods used
to construct or infer (reverse engineer) intracellular networks. We present the graph

  

Source: Albert, Réka - Departments of Biology & Physics, Pennsylvania State University

 

Collections: Biology and Medicine