Summary: Current Biology 18, 1619­1623, October 28, 2008 ª2008 Elsevier Ltd All rights reserved DOI 10.1016/j.cub.2008.08.045
Report
Wnt8 Is Required for Growth-Zone
Establishment and Development
of Opisthosomal Segments in a Spider
Alistair P. McGregor,1,2,3,* Matthias Pechmann,1,2,4
Evelyn E. Schwager,1 Nata´lia M. Feitosa,1 Sarah Kruck,1
Manuel Aranda,1 and Wim G.M. Damen1
1Institute for Genetics
Evolutionary Genetics
University of Cologne
Zu¨ lpicher Straße 47
D-50674, Ko¨ ln
Germany
Summary
The Wnt genes encode secreted glycoprotein ligands that
regulate many developmental processes from axis forma-
tion to tissue regeneration [1]. In bilaterians, there are at
least 12 subfamilies of Wnt genes [2]. Wnt3 and Wnt8 are re-
quired for somitogenesis in vertebrates [3­7] and are

Source: Alwes, Frederike - Department of Organismic and Evolutionary Biology, Harvard University

Collections: Biology and Medicine