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Summary: AR245-NE28-16 ARI 19 May 2005 12:10
An Integrative
Theory of Locus
Coeruleus-Norepinephrine
Function: Adaptive Gain
and Optimal Performance
Gary Aston-Jones1,
and Jonathan D. Cohen2,
1
Laboratory of Neuromodulation and Behavior, Department of Psychiatry, University
of Pennsylvania, Philadelphia, Pennsylvania 19104; email: gaj@mail.med.upenn.edu
2
Department of Psychology, Center for the Study of Brain, Mind and Behavior,
Princeton University, Princeton, New Jersey 08540, and Department of Psychiatry
Western Psychiatric Institute and Clinic University of Pittsburgh, Pittsburgh,
Pennsylvania 15260; email: jdc@princeton.edu
Annu. Rev. Neurosci.
2005. 28:40350
doi: 10.1146/
annurev.neuro.28.061604.135709
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