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Summary: 442 IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE, VOL. 12, NO. 4, JULY 2008
Efficient Lossless Compression of 4-D Medical
Images Based on the Advanced Video
Coding Scheme
Victor Sanchez, Student Member, IEEE, Panos Nasiopoulos, Member, IEEE, and Rafeef Abugharbieh, Member, IEEE
Abstract--This paper presents an efficient lossless compression
method for 4-D medical images based on the advanced video cod-
ing scheme (H.264/AVC). The proposed method efficiently reduces
data redundancies in all four dimensions by recursively apply-
ing multiframe motion compensation. Performance evaluations on
real 4-D medical images of varying modalities including functional
magnetic resonance show an improvement in compression effi-
ciency of up to three times that of other state-of-the-art compres-
sion methods such as 3D-JPEG2000.
Index Terms--3D-JPEG2000, 4-D medical images, H.264/AVC,
lossless compression.
I. INTRODUCTION
MOST current lossless medical image compression meth-
ods are designed to handle 2-D and 3-D data [1][4].
Compression of 4-D medical images is still a relatively new
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