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Summary: vol. 172, no. 6 the american naturalist december 2008
The Role of Heterogeneity in the Persistence and
Prevalence of Sin Nombre Virus in Deer Mice
F. R. Adler,* C. A. Clay,
and E. M. Lehmer
1. Department of Biology and Department of Mathematics,
University of Utah, Salt Lake City, Utah 84112;
2. Department of Biology, Westminster College, Salt Lake City,
Utah 84105;
3. Department of Biology, Fort Lewis College, Durango, Colorado
81301
Submitted October 15, 2007; Accepted July 9, 2008;
Electronically published October 28, 2008
Online enhancements: appendixes.
abstract: Many diseases persist at a relatively low prevalence, seem-
ingly close to extinction. For a chronic disease in a homogeneous
population, reducing the transmission rate by a fraction proportional
to the prevalence would be sufficient to eradicate the disease. This
study examines how higher prevalence of the Sin Nombre virus in
male deer mice (Peromyscus maniculatus) might contribute to disease
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