Summary: Current Biology, Vol. 13, 1029­1037, June 17, 2003, 2003 Elsevier Science Ltd. All rights reserved. DOI 10.1016/S0960-9822(03)00371-3
Asymmetrically Distributed C. elegans Homologs of
AGS3/PINS Control Spindle Position in the Early Embryo
Introduction
Asymmetric cell divisions are important for generating
Monica Gotta,1,3,
* Yan Dong,1
Yuri K. Peterson,2
Stephen M. Lanier,2
and Julie Ahringer1,
*
1
Wellcome/Cancer Research United Kingdom
Institute cell diversity in all eukaryotes [1]. During asymmetric
cell division, the mitotic spindle must be positionedTennis Court Road
University of Cambridge along the axis of polarity to ensure the correct segrega-
tion of determinants to the two daughter cells. However,Cambridge CB2 1QR
United Kingdom how spindle positioning is controlled and how it is coor-
dinated with cell polarity in animal cells is still unknown.2
Department of Pharmacology and Experimental

Source: Ahringe, Julie - Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge

Collections: Biology and Medicine