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Plant Molecular Biology 40: 419429, 1999. 1999 Kluwer Academic Publishers. Printed in the Netherlands.
 

Summary: Plant Molecular Biology 40: 419429, 1999.
1999 Kluwer Academic Publishers. Printed in the Netherlands.
419
Analysis of the C-terminal region of Arabidopsis thaliana APETALA1 as a
transcription activation domain
Sunchan Cho, Seonghoe Jang, Sujin Chae, Kyung Min Chung, Yong-Hwan Moon, Gynheung
An and Sung Key Jang
Department of Life Science, Pohang University of Science and Technology, San 31, Hyoja Dong, Pohang, Kyungbuk
790-784, Korea (author for correspondence)
Received 14 September 1998; accepted in revised form 16 February 1999
Key words: APETALA1 (AP1), Arabidopsis thaliana, transcriptional activator
Abstract
APETALA1 (AP1) of Arabidopsis thaliana is a transcription factor controlling flower development. AP1 is a
member of the MADS (MCM1, AGAMOUS, DEFICIENS, SRF) superfamily, which plays important roles in
differentiation in plants and animals. MADS domains, which function most importantly in DNA binding, are found
in all major eukaryotic kingdoms. In plants, MADS domain-containing proteins also possess a region of moderate
sequence similarity named the K domain, which is involved in protein-protein interaction. Little is known about the
function of a third, highly variable, domain designated the C domain, as it resides at the C terminus of the MADS
proteins of plants. Here we report that the C-terminal domain of Arabidopsis thaliana AP1 and its homologues
perform a transcriptional activation function. The C-terminal region of AP1 is composed of at least two separable

  

Source: An, Gynheung - Department of Life Science, Pohang University of Science and Technology

 

Collections: Biotechnology; Biology and Medicine