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Plant-like traits associated with metabolism of Trypanosoma parasites
 

Summary: Plant-like traits associated with metabolism of
Trypanosoma parasites
Ve´ronique Hannaert*, Emma Saavedra*
, Francis Duffieux*
, Jean-Pierre Szikora*, Daniel J. Rigden§
,
Paul A. M. Michels*, and Fred R. Opperdoes*¶
*Research Unit for Tropical Diseases and Laboratory of Biochemistry, Christian de Duve Institute of Cellular Pathology and Universite´ Catholique de Louvain,
B-1200 Brussels, Belgium; and §Embrapa Genetic Resources and Biotechnology, 70770-900 Brasilia-DF, Brazil
Edited by P. Borst, The Netherlands Cancer Institute, Amsterdam, The Netherlands, and approved December 6, 2002 (received for review
September 23, 2002)
Trypanosomatid parasites cause serious diseases among humans,
livestock, and plants. They belong to the order of the Kinetoplas-
tida and form, together with the Euglenida, the phylum Eugleno-
zoa. Euglenoid algae possess plastids capable of photosynthesis,
but plastids are unknown in trypanosomatids. Here we present
molecular evidence that trypanosomatids possessed a plastid at
some point in their evolutionary history. Extant trypanosomatid
parasites, such as Trypanosoma and Leishmania, contain several
``plant-like'' genes encoding homologs of proteins found in either

  

Source: Arnold, Jonathan - Nanoscale Science and Engineering Center & Department of Genetics, University of Georgia

 

Collections: Biotechnology