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Respiratory Physiology #3 Regulation of Blood pH
 

Summary: Respiratory Physiology #3
Regulation of Blood pH
Neural Control of Respiratory Rate
Determinants of Respiratory Rate CO2 and O2
Ventilation-Perfusion Mismatch
Interpretation of Arterial Blood Gases
Myles Akabas
Blood pH is Tightly Regulated
Normal pH = 7.40 + 0.04 [H+] = 3.9 x 10-8 M
pH limits compatible with life 6.9 to 7.8
Blood is highly buffered to prevent fluctuations in pH
CO2 + H2O H2CO3 H+ + HCO3
-
CO2/HCO3
- buffer system is the major blood pH buffer
carbonic
anhydrase
Blood pH is Regulated by PCO2 and the [HCO3
-]
CO2 + H2O H2CO3 H+ + HCO3

  

Source: Akabas, Myles - Department of Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University

 

Collections: Biology and Medicine