Laboratory evolutionists continue to generate better enzymes for
industrial and research applications. Exciting developments include
new biocatalysts for enantioselective carboncarbon bond
formation and fatty acid production in plants. Creative contributions
to the repertoire of evolutionary methods will ensure further growth
in applications and expand the scope and complexity of biological
design problems that can be addressed. Researchers are also
starting to elucidate mechanisms of enzyme adaptation and natural
evolution by testing evolutionary scenarios in the laboratory.
Division of Chemistry and Chemical Engineering 210-41,
California Institute of Technology, Pasadena, CA 91125, USA;
*These authors contributed equally to this work.
Current Opinion in Biotechnology 2001, 12:545551
0958-1669/01/$ -- see front matter
© 2001 Elsevier Science Ltd. All rights reserved.
CSR compartmentalized self-replication