Summary: Brain Imaging Findings
in Neuropathic Pain
Paul Y. Geha, MD and A. Vania Apkarian, PhD*
*Northwestern University Feinberg School of Medicine, Department of
Physiology, 303 East Chicago Avenue, Chicago, IL 60611, USA.
Current Pain and Headache Reports 2005, 9:184188
Current Science Inc. ISSN 1531-3433
Copyright © 2005 by Current Science Inc.
Neuropathic pain remains an ill-defined condition. It is a
clinical pain syndrome usually associated with a lesion to
the nervous system [1,2·]. Such lesions can occur at many
different levels, starting from peripheral nerves (posther-
petic neuralgia), then the spinal cord (postspinal cord
injury pain), to the brain itself (thalamic pain syndromes).
However, only a small portion of people with such injuries
develop chronic neuropathic pain. It is extensively studied
in animal models and the work done thus far has uncov-