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Summary: Algorithms 2009, 2, 582-605; doi:10.3390/a2010582
algorithms
ISSN 1999-4893
www.mdpi.com/journal/algorithms
Review
Recent Advances in the Computational Discovery of
Transcription Factor Binding Sites
Tung T. Nguyen 1,
* and Ioannis P. Androulakis 2,
*
1
BioMaPS Institute for Quantitative Biology, Rutgers University, New Jersey 08854, USA
2
Biomedical Engineering Department, Rutgers University, New Jersey 08854, USA
E-mails: nthtung@biomaps.rutgers.edu, yannis@rci.rutgers.edu
* Author to whom correspondence should be addressed.
Received: 6 January 2009 / Accepted: 17 March 2009 / Published: 24 March 2009
Abstract: The discovery of gene regulatory elements requires the synergism between
computational and experimental techniques in order to reveal the underlying regulatory
mechanisms that drive gene expression in response to external cues and signals. Utilizing
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