Summary: Modeling, Mutagenesis, and Structural Studies on the Fully
Conserved Phosphate-Binding Loop (Loop 8) of
Triosephosphate Isomerase: Toward
a New Substrate Specificity
Brian V. Norledge,1,2
Anne M. Lambeir,3
Ruben A. Abagyan,4
Antje Rottmann,5
Anna M. Fernandez,6
Vladimir V. Filimonov,6
Martin G. Peter,5
and Rik K. Wierenga1,2*
1
Biocenter Oulu and Department of Biochemistry, University of Oulu, Linnanmaa, Oulu, Finland
2
European Molecular Biology Unit (EMBL), Heidelberg, Germany
3
Laboratory of Medical Biochemistry, University of Antwerp (UIA), Wilrijk, Belgium
4
Department of Molecular Biology, MB-37, Scripps Research Institute, La Jolla, California

Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego

Collections: Biology and Medicine