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A Myo7a mutation cosegregates with stereocilia defects and low-frequency hearing impairment
 

Summary: A Myo7a mutation cosegregates with stereocilia defects and
low-frequency hearing impairment
Charlotte R. Rhodes,1
* Ronna Hertzano,2
* Helmut Fuchs,3
Rachel E. Bell,2
Martin HrabeŽ de Angelis,3
Karen P. Steel,1
Karen B. Avraham2
1
MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, UK
2
Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
3
GSF Research Center for Environment and Health, Institute of Experimental Genetics, Neuherberg, Germany
Received: 28 October 2003 / Accepted: 7 May 2004
Abstract
A phenotype-driven approach was adopted in the
mouse to identify molecules involved in ear devel-
opment and function. Mutant mice were obtained

  

Source: Avraham, Karen - Department of Human Genetics and Molecular Medicine, Tel Aviv University

 

Collections: Biology and Medicine