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Murine gammaherpesvirus-induced fibrosis is associated with the development of alternatively activated macrophages
 

Summary: Murine gammaherpesvirus-induced fibrosis is associated with
the development of alternatively activated macrophages
Babunilayam Gangadharan,*,1,2
Marieke A. Hoeve,,1
Judith E. Allen,
Bahram Ebrahimi,
Susan M. Rhind,
Bernadette M. Dutia,* and Anthony A. Nash*,3
*Centre for Infectious Diseases,
Division of Veterinary Clinical Sciences, Royal (Dick) School of Veterinary Studies,
and
The Institute of Immunology and Infection Research, University of Edinburgh, United Kingdom; and
Division
of Medical Microbiology, School of Infection and Host Defence, University of Liverpool, United Kingdom
Abstract: Murine gammaherpesvirus 68 (MHV-68)
is a natural pathogen of rodents closely related to
the human herpesviruses Kaposi's sarcoma-asso-
ciated herpesvirus and EBV. Following intranasal
infection, the virus replicates in the lung epithe-
lium prior to establishing latent infection in lym-

  

Source: Allen, Judith - School of Biological Sciences, University of Edinburgh

 

Collections: Biology and Medicine