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Summary: Dendritic Spines: hippocampus
Wednesday, November 10, 2010
Dendritic Spines
Wednesday, November 10, 2010
Neuronal Signal Transduction
· Neurotransmitter receptors
Inotropic receptors
Metabotropic receptors
· Second messengers and neuromodulation
Protein kinases
2nd messenger interaction
Regulation of receptor sensitivity
Regulation of ion channel function
Wednesday, November 10, 2010
Some properties of neurotransmitter receptors
· Transmembrane proteins
· Rapid and reversible agonist binding
· Stereoselectivity (d vs. l NE)
· One neurotransmitter: multiple receptors
· Multiple affinity states for agonist binding
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