Home

About

Advanced Search

Browse by Discipline

Scientific Societies

E-print Alerts

Add E-prints

E-print Network
FAQHELPSITE MAPCONTACT US


  Advanced Search  

 
In the past our group has shown that the ultrasound power backscattered from subvolumes of in vitro tissue preparations is
 

Summary: Abstract
In the past our group has shown that the ultrasound power
backscattered from subvolumes of in vitro tissue preparations is
dependent on the temperature of the tissue. The backscattered
power tends to monotonically increase or decrease depending on the
dominant type of scatterer within the subvolume. We have extended
this research to an in vivo system to test this hypothesis in living
perfused tissue. The animal system consisted of nude mice with
implanted tumors (HT29 colon cancer line) on their hind quarters.
The mice were anesthetized with Ketamine Xylazine prior to being
secured to a platform. The platform and lower section of the mouse
were submerged in a temperature controlled water bath filled with
degassed water. The temperature of the mouse was measured with
an implanted thermistor in a contralateral limb which had a similar
implanted tumor and was similarly submerged in the water bath. The
transducer from a commercial laptop-based ultrasound system
(Terason 2000, Teratech Corporation) was coupled to the target
tumor through the water bath and images of the heated tumor were
acquired at 0.5 oC increments from 37.0 to 45.0 oC. These data are
being analyzed in a manner similar to that used for data acquired

  

Source: Arthur, R. Martin - Department of Electrical and Systems Engineering, Washington University in St. Louis

 

Collections: Biology and Medicine; Engineering