Summary: © 2007 Nature Publishing Group
letters
Phosphoregulation and depolymerization-driven
movement of the Dam1 complex do not require ring
formation
Daniel R. Gestaut1
, Beth Graczyk1
, Jeremy Cooper2
, Per O. Widlund1
, Alex Zelter1
, Linda Wordeman2
,
Charles L. Asbury2
, Trisha N. Davis1,3
During mitosis, kinetochores form persistent attachments
to microtubule tips and undergo corrective detachment in
response to phosphorylation by Ipl1 (Aurora B) kinase1
.
the Dam1 complex is required to establish and maintain
bi-oriented attachment to microtubule tips in vivo, and it

Source: Asbury, Chip - Department of Physiology and Biophysics, University of Washington at Seattle

Collections: Biology and Medicine