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Summary: ..............................................................
Genome-wide RNAi analysis
of Caenorhabditis elegans
fat regulatory genes
Kaveh Ashrafi*, Francesca Y. Chang*, Jennifer L. Watts,
Andrew G. Fraser§, Ravi S. Kamath§, Julie Ahringer§ & Gary Ruvkun*
* Department of Molecular Biology, Massachusetts General Hospital, Boston,
Massachusetts 02114, USA
Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114,
USA
Institute of Biological Chemistry, Washington State University, Pullman,
Washington 99164, USA
§ Wellcome/Cancer Research UK Institute, University of Cambridge, Tennis Court
Road, Cambridge CB2 IQR, UK
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Regulation of body fat storage involves signalling between
centres that regulate feeding in the brain and sites of fat storage
and use in the body1,2
. Here we describe an assay for analysing fat
storage and mobilization in living Caenorhabditis elegans. By
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