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Fully-Automated Analysis of Multi-Resolution Four-Channel Microarray Genotyping Data
 

Summary: Fully-Automated Analysis of Multi-Resolution Four-Channel
Microarray Genotyping Data
Mohsen Abbaspoura
, Rafeef Abugharbieha
, Mohua Podderb
, and Scott J. Tebbuttc
a
Department of Electrical and Computer Engineering, University of British Columbia,
Vancouver, BC, V6T 1Z4, Canada;
b
Department of Statistics, University of British Columbia, Vancouver, BC, V6T 1Z2, Canada;*
c
iCAPTURE Centre (Department of Medicine), St. Pauls's Hospital, University of British Columbia,
Vancouver, BC, V5Z 4E3, Canada
ABSTRACT
We present a fully-automated and robust microarray image analysis system for handling multi-resolution images (down
to 3-micron with sizes up to 80 MBs per channel). The system is developed to provide rapid and accurate data extraction
for our recently developed microarray analysis and quality control tool (SNP Chart). Currently available commercial
microarray image analysis applications are inefficient, due to the considerable user interaction typically required. Four-
channel DNA microarray technology is a robust and accurate tool for determining genotypes of multiple genetic markers

  

Source: Abugharbieh, Rafeef - Department of Electrical and Computer Engineering, University of British Columbia

 

Collections: Biology and Medicine; Computer Technologies and Information Sciences