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Sample search results for: a2 receptor expression

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1 In this thesis a combined approach is described to investigate the constitutive activity of G protein protein-coupled receptors (GPCRs) using human adenosine A2B receptors and to
 

Summary:  activity of G protein protein-coupled receptors (GPCRs) using human adenosine A2B receptors and to evaluate... and 4 the yeast system is exploited to study inverse agonism of the human adenosine A2B receptor... . At first, constitutively active ...

  

Source: van den Brink, Jeroen - Leiden Institute of Physics, Universiteit Leiden

 

Collection: Physics

 
2 This article was originally published in the Encyclopedia of Neuroscience published by Elsevier, and the attached copy is provided by Elsevier for the
 

Summary:  Four different P1 receptor subtypes, A1, A2A, A2B, and A3, have been cloned. All are G... -protein-coupled receptors (GPCRs). At 318 amino acids in length, the A3 subtype is the shortest, while A2A is the longest... are ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
3 J Neural Transm (2007) 114: 4975 DOI 10.1007/s00702-006-0589-0
 

Summary:  expressing stable A2A receptors (HA-A2A=D2 cell line), and the clones resistant to geneticin and hygromycin... for treatment of Parkinson's disease (A2A and mGluR5 receptor antagonists), schizophrenia ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
4 Enhancement of the surface expression of G protein-coupled receptors
 

Summary:  receptors [49], Usp4, which increases plasma membrane expression of adenosine A2A receptors [50], ATBP50... . (2008) RACK1 regulates the cell surface expression of the G protein-coupled receptor for thromboxane ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
5 JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION Vol. 24, No. 3, pp. 165205, 2004
 

Summary:  region with the densest dopamine innervation and the highest expression of the D1 receptor, expression... 1 receptor activation of adenylate cyclase is Gs#12;1 7. Because 7 is abundantly expressed... in neostriatal medium spiny neurons (10), particularly in neurons that also ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
6 P2 receptor web: Complexity and fine-tuning Cinzia Volont a,, Susanna Amadio a
 

Summary:  . . . . . . . . . . . . . . . . . . . . . . 270 3.3. Plasticity of receptor expression, including development... expression of P2X2, P2X3, P2X4, P2X5, and P2X6 receptors. In addition, this motif regulates the P2X receptors... receptors are differently ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
7 The potent pharmacological effects of opiates have been recognized by humans since ancient times. Today,
 

Summary:  in functionally different receptors. Native NMDA receptors comprise subunits that include NR1, NR2A­2D and NR3A... ofAMPA receptor mRNA expression and [3H]AMPA binding in various brain sites in the rat25. Second... receptors,AMPA ...

  

Source: Barr, Gordon A. - Department of Psychology, Hunter College, City University of New York

 

Collection: Biology and Medicine

 
8 INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE Olfactory Receptor Interactions
 

Summary:  receptors, and A2A adenosine receptor. These four receptors were further- more found... Olfactory receptors expressed in heterologous cells often suffer from retention in the endoplasmic reticulum... could be differentially influenced by the ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
9 Copyright C Blackwell Munksgaard 2002 Traffic 2002; 3: 866877
 

Summary:  and F251A) or inactivate the receptor (like N296A) [(2,3) and references 873Traffic 2002; 3: 866... , Strnad J, Pausch MH, Hadcock JR. Pharmacological char- acterization of the rat A2a adenosine receptor... expressing the recombinant ...

  

Source: Bourne, Henry - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
10 AMPA receptor desensitization mutation results in severe developmental phenotypes and early
 

Summary:  receptor subunits GluA1 and GluA2 was decreased, whereas NMDA receptor protein expression was increased... in area CA1 of the hippocampus (Fig. 1 H and I). Glutamate Receptor Expression Is Altered in ...

  

Source: Contractor, Anis - Department of Physiology, Northwestern University

 

Collection: Biology and Medicine

 
11 Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional Significance
 

Summary:  GPCRs (A1, A2A, A2b, and A3), whereas ATP activates P2X receptors, which are ion channels, as well... between adenosine and dopa- mine receptors, the A1R/mGluR1 and A2AR/mGluR5 in- teractions facilitate... . (2003) Adenosine ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
12 The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor
 

Summary:  endogenous P2Y receptors in addition to the P1 adenosine receptors A2A and A2B, which might complicate... are influenced by a physical interaction between GPR80/GPR99 and endogenous P2Y or A2B receptors, ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
13 Ligand Stabilization of the 2 Adrenergic Receptor: Effect of DTT on Receptor Conformation Monitored by Circular Dichroism and Fluorescence Spectroscopy
 

Summary:  of native and denatured 2 receptor. Far- UV CD spectra of affinity-purified 2 receptor (trace a), 2 receptor... -Tris buffer (trace a), 2 receptor treated with 10 mM DTT for 1 h at room temperature (trace b), and 2 ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
14 DOI: 10.1113/jphysiol.2007.131367 2007;581;3-; originally published online Mar 22, 2007;J. Physiol.
 

Summary:  and laboratory animals, the major feature of deficient glycine receptor expression or function is an exaggerated... (Burzomato C AC A2C A3C AF A2F A3F AO A2O A3O CLOSED FLIPPED OPEN C AC ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
15 Olfactory receptor trafficking to the plasma membrane C. F. Bush and R. A. Hall*
 

Summary:  A2a receptors, were all found to signifi- cantly enhance the plasma membrane localization of M71... performed in heterologous cells and it is not clear whether b2-adrenergic, P2Y1, P2Y2, and A2a receptors... of b2-adrenergic, P2Y1, P2Y2, and ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
16 Evidence of a specific role for 5-HT2A and 5-HT7 receptors in hindlimb stepping generation induced pharmacologically in paraplegic mice.
 

Summary:  rhythmogenesis. In contrast to the pro-locomotor effect of quipazine (5-HT2A/2C agonist), m-CPP (5-HT2B/2C... Evidence of a specific role for 5-HT2A and 5-HT7 receptors in hindlimb stepping generation induced... City, Canada. 2. Department of Physiology, Emory University, Atlanta. Serotonin (5-HT) receptor

  

Source: Hochman, Shawn - Department of Physiology, Emory University

 

Collection: Biology and Medicine

 
17 Dual constrictor and dilator actions of ETB receptors in the rat renal microcirculation: interactions with ETA receptors
 

Summary:  are limited to smooth muscle cells, whereas ETB receptors are expressed in both endothelial and smooth muscle... receptor inhibition by infusion of BQ-123 BQ-788 together (n 6) is shown. RBF is expressed as percent... -1-induced release of thromboxane A2 from the ...

  

Source: Just, Armin - Physiologisches Institut I, Albert-Ludwigs-Universität Freiburg

 

Collection: Biology and Medicine

 
18 Brain Research 869 (2000) 178185 www.elsevier.com/locate/bres
 

Summary:  and methods 5-HT , 5-HT , 5-HT and dopamine receptors showed2A 2C 7 that the wild-type mice, but not the 5-HT... : 11-859-323- protein coupled receptor [8,10], is expressed in many brain5946. E-mail address: mjdunc0... previously shown to express 5-HT ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
19 Hetero-oligomerization between GABAA and GABAB Receptors Regulates GABAB Receptor Trafficking*
 

Summary:  of the GABAB receptor 1 (GABABR1) with the GABAA receptor 2S subunit robustly promotes cell surface expression... to effectors than native GABAB receptors (6). It was soon established that GABABR1, when expressed alone... were co-expressed in heterologous cells, they ...

  

Source: Teissére, Jeremy Alden - Biology Department, Muhlenberg College

 

Collection: Biology and Medicine

 
20 Hetero-oligomerization between GABAA and GABAB Receptors Regulates GABAB Receptor Trafficking*
 

Summary:  by Ken Minneman (Emory University School of Medicine). 2A-, 2B-, and 2C-adrenergic receptor constructs... of the GABAB receptor 1 (GABABR1) with the GABAA receptor 2S subunit robustly promotes cell surface expression... to effectors than native GABAB ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine


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21 1. MadinDarby canine kidney (MDCK) cells, a well-differentiated renal epithelial cell line derived from distal
 

Summary:  in response to many different types of activators of phospholipase (PL)A2, including receptor... evidence for expression of at least three P2Y receptor subtypes (P2Y1, P2Y2 and P2Y11) in MDCK-D1 cells... antagonists; and (iii) RT-PCR, cloning and expression of ...

  

Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center

 

Collection: Biology and Medicine

 
22 PATTERNS & PHENOTYPES Abundant and Dynamic Expression of G Protein-
 

Summary:  PATTERNS & PHENOTYPES Abundant and Dynamic Expression of G Protein- Coupled P2Y Receptors... in many cell types. Yet the expression and function of the P2Y receptors in development has rarely been... expression of P2Y receptors in rat development. These ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
23 Agonist-induced polarized trafficking and surface expression of the adenosine 2b receptor in intestinal epithelial cells: role of SNARE proteins
 

Summary:  ). Interestingly, the A2b receptor is the predom- inant adenosine receptor expressed in the cecum and colon as well... colonic epithelia T84 cells, the A2b receptor is the only adenosine receptor ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
24 Interneuron Diversity series Diversity of inhibitory
 

Summary:  -positive interneurons innervate somatic GABAA receptors with a large a1:a2 subunit ratio [35]. This clear segregation... of synapse because, in expression systems, a2-subunit-containing GABAA recep- tors deactivate more slowly... receptor ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
25 The concept of purinergic neurotransmission was pro-posed in 1972 (REF. 1), after it was shown that adenosine
 

Summary:  . expression of A2A receptors in the brain of patients with Parkinson's disease and dyskinesia is increased70... disorders, highlighting specific purinergic receptor subtypes, most notably A2A , P2X4 and P2X7 ,that might... in rodents, which is ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
26 Diffusion-Dependent Mechanisms of Receptor Engagement and Viral Entry Melissa M. Gibbons,
 

Summary:  in units of a, the radius of the virus spike-cell membrane contact area, and time in units of a2 /p... . As degradation expressed via µ0 increases, viral entry can occur only if viruses bind receptors quickly, rj ) r... a , tj ) tp a2 , cj(rj, tj) ) ...

  

Source: D'Orsogna, Maria Rita - Department of Mathematics, California State University, Northridge

 

Collection: Mathematics

 
27 Relating NMDA Receptor Function to Receptor Subunit Composition: Limitations of the Pharmacological Approach
 

Summary:  , as discussed below, ifenprodil not only affects NR1/NR2B receptors but also triheteromeric NR1/2A/2B receptors... (5):1331­1333 Neyton and Paoletti · Commentary #12;receptors are present in the cortex and hippocampus and NR1/2A/2C... ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
28 Richard Huganir () DirectorDepartment of Neuroscience, Howard Hughes Medical Institute,
 

Summary:  of the AMPA receptor GluR1 subunit is required for the expression of these forms of plasticity... Hopkins University School of Medicine Receptors, Synapses and Memories COE 2450 20 5 30 13... Neurotransmitter receptors mediate signal transduction at the postsynaptic membrane of synaptic ...

  

Source: Miyashita, Yasushi - Department of Physiology, University of Tokyo

 

Collection: Biology and Medicine

 
29 Purine and pyrimidine receptors G. Burnstock
 

Summary:  by ectonucleotidases. Four subtypes have been identified, A1, A2A, A2B and A3 receptors. P2 receptors are activated... different P1 receptor subtypes, A1, A2A, A2B ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
30 Purine and pyrimidine receptors G. Burnstock
 

Summary:  , complementary DNAs (cDNAs) encoding two different P1 receptor subtypes (A1 and A2) were isolated [20], and... , shortly after, the A3 subtype was identified [21]. Four different P1 receptor subtypes, A1, A2A, A2B and A... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
31 Purinoceptors on Neuroglia Alexei Verkhrasky & Oleg A. Krishtal &
 

Summary:  to several families of Gi and Go proteins. Four types of adenosine receptors (A1, A2A, A2B and A3... to A1 and A2 types were identified in human foetal astrocytes [68]. In these cells, the A1 receptors... inhibited, whereas ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
32 Current Pharmaceutical Design, 2004, 10, 000-000 1 1381-6128/04 $45.00+.00 2004 Bentham Science Publishers Ltd.
 

Summary:  rapid release of arachidonic acid in monocytes by activation of phospholipase A2 in a calcium dependent... and PTX-sensitive manner [28]. Activation of phospholipase A2 is involved in monocyte polarization... and chemotaxis induced by MCP-1 because this effect is blocked by inhibitors of phospholipase ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
33 ELSEVIER Immunopharmacology33 (1996) 9-15 Immunophannacology
 

Summary:  produce pathophysiologic quantities of mediators such as TxA 2, independent of BK receptor mechanisms... receptor-mediated activationof phospholipaseA2 in 3T3 fi- broblasts. Proc. Natl. Acad. Sci. USA 1988... . Bradykinin (BK) represents such a versatile ...

  

Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
34 ORIGINAL ARTICLE Cells in Behaviourally Relevant Brain Regions Coexpress Nuclear Receptor
 

Summary:  is the induction of progesterone receptor (PR) expression in a variety of behaviourally relevant brain regions... expression in the VMN is important for progesterone-facilitated reproductive behaviour (18). Nuclear receptor... coactivators (32). The p160 family also includes SRC-2 (also known as ...

  

Source: Tetel, Marc J. - Department of Biological Sciences, Wellesley College

 

Collection: Biology and Medicine

 
35 J Physiol 588.1 (2010) pp 9399 93 SYMPOSIUM REVIEW
 

Summary:  adenosine A2A receptors are essential for inducing LTP of NMDA-EPSCs (Rebola et al. 2008). A2A receptors may... of mossy fibres lead to the activation of NMDA, mGluR5 and adenosine A2A receptors that ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
36 Neuregulin1 Downregulates Postsynaptic GABAA Receptors at the Hippocampal Inhibitory Synapse
 

Summary:  the expression of specific neuro- transmitter receptor subunits. In the present report, we show that... in the hippocampal inhibitory synapse is downregulation, rather than upregula- tion, of receptor subunit expression... Changes in the level of expression and distribution of ...

  

Source: Corfas, Gabriel - F.M. Kirby Neurobiology Center, Children's Hospital Harvard Medical School

 

Collection: Biology and Medicine

 
37 REVIEW ARTICLE Chemokine receptors and other G protein-coupled receptors
 

Summary:  of invertebrate rhodopsin, b1-adrenergic and b2-adrenergic receptors and the A2A-adenosine receptor have been... -adrenergic and b2-adrenergic receptors, and most recently, the structure of the A2A adenosine receptor [26... ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
38 Complex expression of natural killer receptor genes in single natural killer cells ZAHEED HUSAIN,*{{ CHESTER A. ALPER,{1 EDMOND J. YUNIS*{ &
 

Summary:  for HLA-C (HLA-A2, A11, B27, B51, Cw1, Cw2). The donors A, B and C had expression of all genes 2DL1, 2DL2... Complex expression of natural killer receptor genes in single natural killer cells ZAHEED HUSAIN... , USA SUMMARY Human natural killer (NK) cells express ...

  

Source: Alper, Chester A. - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
39 An escort for GPCRs: implications for regulation of receptor density at the cell Lamia Achour1,2
 

Summary:  surface expression of the G protein- coupled receptor for thromboxane A(2). Traffic 9, 394-407 72. Chen, C... for Activated C-Kinase 1)71 . RACK1 is an ER protein that constitutively binds the thromboxane A2 receptor (TPß... , suggesting ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
40 Neurons respond to a variety of attractive and repulsive guid-ance cues to navigate to their targets1. Genetic, biochemical and
 

Summary:  . Nasal axons express ephrin-A2 and ephrin-A5 as well as a moderate level of Eph receptors... on nasal axons. Ephrin-A2 and ephrin-A5 are expressed in high-nasal­to­low-temporal gradi- ents in retinal... with the metalloprotease kuzbanian, which ...

  

Source: Bargmann, Cori - Laboratory of Neural Circuits and Behavior, Rockefeller University

 

Collection: Biology and Medicine


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41 nature neuroscience volume 1 no 7 november 1998 563 Nervous system signaling depends on the spatially and tempo-
 

Summary:  almost completely colocalized with punctate staining of the GABAA receptor 2 (Fig. 5a), 2 (Fig. 5c) or 1... GABAergic func- tion. Conversely, inhibiting gephyrin expression causes loss of GABAA receptor clusters... , immunocytochemical analyses of the 2, 1 and 2 sub- units (three major ...

  

Source: Luscher, Bernhard - Department of Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
42 2001 Wiley-Liss, Inc. DRUG DEVELOPMENT RESEARCH 52:110 (2001)
 

Summary:  were cloned, namely, A1, A2A, A2B, and A3 [Ralevic and Burnstock, 1998]. P2X Receptor Family P2X... of skeletal muscle, changes in receptor expression in smooth-muscle phenotypes, maturation of testicular... - ogy of the recombinant P2X ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
43 Current Pharmaceutical Design, 2009, 15, 000-000 1 1381-6128/09 $55.00+.00 2009 Bentham Science Publishers Ltd.
 

Summary:  to adenosine, it acts as a prejunctional inhibitor of transmission via P1(A2) purinoceptors. P2X3 receptors... 1, A2A, A2B, and A3 (see [53]). All P1 adenosine receptors couple to G proteins and, in common... ]) and that ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
44 Bruce N. Cronstein, MD You Are Not Arthur Conan Doyle
 

Summary:  A2A receptors in fibrosis in tissues outside of the skin is less clear... . Prior studies have demonstrated that adenosine A2B receptors regulate production... to the nucleus thereby promoting fatty ...

  

Source: Wang, Da-Neng - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University

 

Collection: Biology and Medicine

 
45 NMDA receptor subunit gating uncovered Alasdair J. Gibb
 

Summary:  and Jahr [16], oscillation into and out of a rela- tively long-lived shut state, A2RD (desensitized state... and Traynelis [1]. Two new states, A2Rf and A2Rs, reflect the fast gating transitions of the NR1 subunits (kþf... order to arrive at the ...

  

Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
46 Associate editor: A.L. Morrow Regulation of GABAA receptor trafficking, channel activity,
 

Summary:  -deficient mice (Gu¨n- ther et al., 1995). Clustering of a1 and a2 subunit-containing receptor subtypes is reduced... ;rescues clustering of a1 and a2 subunit-containing receptors in the cerebellum and hippocampus... - containing receptors mediate ...

  

Source: Luscher, Bernhard - Department of Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
47 Glycosylation of b1-adrenergic receptors regulates receptor surface expression and dimerizationq
 

Summary:  the b2-adrenergic receptor [15], a2A-adrenergic re- ceptor [30], and dopamine D1 receptor [31]. Con... - adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of a2... Glycosylation of b1-adrenergic ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
48 doi:10.1152/ajpgi.00147.2006 291:605-610, 2006. First published May 4, 2006;Am J Physiol Gastrointest Liver Physiol
 

Summary:  ). Current understanding of G protein coupling of S1P recep- tors is based on receptor expression studies... in cell lines. In cells expressing S1P1 receptors, S1P stimulates phosphoinosi- tide (PI) hydrolysis, Ca2... expressing S1P2 or S1P3 receptors, S1P stimulates ...

  

Source: Hu, Wen-Hui - Department of Physiology, Virginia Commonwealth University

 

Collection: Biology and Medicine

 
49 Diinosine pentaphosphate: an antagonist which discriminates between recombinant P2X3 and P2X2/3 receptors and between two
 

Summary:  pentaphosphate (Ip5I) is a very potent antagonist at recombinant P2X1 receptors (pA2, 8.2) and is quite active... at P2X3 receptors with a pA2 of 6.3 (King et al., 1999). In this study, we have investigated... of trinitrophenyl-ATP (TNP-ATP) and diinosine ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
50 The serotonergic system The Serotonergic System
 

Summary:  5-HT1B receptor. The 5-HT1B receptor is widely expressed in brain tissue, probably in both... that when expressed at high concentrations in CHO or Y1 adrenal cells, this receptor can weakly stimulate c... expression studies have shown that there are brain regions ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
51 Original Article Increased expression of the pro-apoptotic ATP-sensitive P2X7
 

Summary:  Original Article Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor... . Therefore, we wanted to investigate if expression of this receptor is altered in the glomeruli of rodent... models of glomerulonephritis. Methods. P2X7 receptor protein ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
52 TRENDS in Pharmacological Sciences Vol.22 No.4 April 2001 http://tips.trends.com 0165-6147/01/$ see front matter 2001 Elsevier Science Ltd. All rights reserved. PII: S0165-6147(00)01643-6
 

Summary:  , four subtypes of adenosine (P1) receptors were cloned [A1 , A2A , A2B and A3 (Ref. a)]. P2X receptor... A2 receptors; however, it might also act (broken arrow) to potentiate P2X3 or P2X2/3 activation... . ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
53 hal-00139989,version1-4Apr2007 Author manuscript, published in "Neuron 46, 2 (2005) 261-74" DOI : 10.1016/j.neuron.2005.03.005
 

Summary:  and NR1/2A/2C triheteromeric NMDA receptors (A) Glutamate concentration-response curves for oocytes... , approximately 90% of the current is carried by triheteromeric NR1/2A/2AH128SN614K receptors (see Results). Note... that this curve is almost identical to that ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
54 Progress in Neurobiology 70 (2003) 387407 Kainate receptors and synaptic transmission
 

Summary:  ). A great deal has been learned from studies in which kainate receptor subunits were expressed in Xenopus... on the combinatorial mixing of five dif- ferent subunits. The distribution of cells expressing kainate receptor mR- NAs... hybridization, cells displaying prominent expression of ...

  

Source: Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
55 Coexpression of P2X3 and P2X2 Receptor Subunits in Varying Amounts Generates Heterogeneous Populations of P2X
 

Summary:  on Xenopus oocytes, agonist- evoked ionic currents by P2X receptors resulting from the co- expression of P2X2... neurons that also express P2X2 and P2X3 subunits in different amounts. P2X receptors represent a family... in the operational profile of native P2X receptors may be due to ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
56 ______________________________________________________Summary Cannabis sativa has been used by humanity as a source of weaving material as
 

Summary:  downstream of the CB1-receptor, phospholipase A2 and MAP kinases. The non-selective Ca2+ -antagonists La3... of the drug. In recent years, the discovery of the existence and expression of two cannabinoid receptors (CBB... by CP55,940. This release was fully inhibited by the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
57 The International Journal of Biochemistry & Cell Biology 35 (2003) 130134 Molecules in focus
 

Summary:  -directional signaling cascades where information is transduced in both the receptor- and the ligand-expressing cells... receptor forward signal into the receptor-expressing cell, the interactions between Ephs and ephrins also... including the Ryk receptor. In the ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
58 Purinergic signalling: therapeutic potential* GEOFFREY BURNSTOCK
 

Summary:  receptors were cloned, namely A1, A2A, A2B and A3 and in 1985, Burnstock and Kennedy proposed a basis... . Blockade of A2A (P1) receptors antagonises parkinsonian tremor in the rat tacrine model by actions... on specific ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
59 Transmembrane signalling and the aspartate receptor William G Scott1 and Barry LStoddard 2*
 

Summary:  , and Cys4/36 cross-linked receptor (Fig. 6). In addition, bacteria expressing the various receptor con... by calculating the total buried surface area in the coiled coil model (-1800 A2 ), the number of side chain... , and similar expression vectors encoding ...

  

Source: Scott, William - Department of Chemistry and Biochemistry, University of California at Santa Cruz

 

Collection: Chemistry

 
60 The role of ephrins and Eph receptors in cancer Hanna Surawska, Patrick C. Ma, Ravi Salgia*
 

Summary:  the receptor's role in p53-mediated tumor suppression, Dohn et al. produced exogenous EphA2-expressing cell... that EphA2 expression in stable H1299 and MCF-7 cell lines resulted in increased apoptosis. 4. Biological... and surgically removed ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine


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61 EDITED B'r' Bertha K. Madras Harvard Medical School
 

Summary:  , and serotonin (5-HT3) receptors. Currently, 12 neu- ronal nAChR subunits have been identified (a2--a1 0 and 132... nicotinic acetylcholine receptor: structure and localization. (A) Topology of a single subunit (a2-al 0; 132... ) Mesocorticolimbic circuitry in the ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
62 Modulation of triheteromeric NMDA receptors by N-terminal domain ligands
 

Summary:  sensitivity of triheteromeric NR1/2A/2C receptors, we co-expressed NR1, NR2C and NR2AN614KT690I subunits... . Similarly, NR1/2A/2C receptors are inhibited by zinc with high potency but low efficacy. Therefore... triheteromeric ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
63 Current Topics in Medicinal Chemistry 2004, 4, 793-803 793 1568-0266/04 $45.00+.00 2004 Bentham Science Publishers Ltd.
 

Summary:  express multiple P2Y subtypes [18]. P2Y receptors show a low level of sequency homology at the peptide... activate phospholipases A2, C and D, MEP/MAP kinase, Rho-dependent kinase and tyrosine kinase, as well... ]. The autonomic nervous system shows marked plasticity, i.e. the expression ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
64 Z .European Journal of Pharmacology 405 2000 7388 www.elsevier.nlrlocaterejphar
 

Summary:  on several criteria of specificity. First, the pA2 value for the V antagonist for vasopresser activity was1 8... expressed both vasopressin V receptors and b -adrenoceptors. The1 1 distribution of vasopressin V receptors... The dentate gyrus expressed a consistently ...

  

Source: Brinton, Roberta Diaz - Laboratory for Neuroscience Research & School of Pharmacy, University of Southern California

 

Collection: Biology and Medicine

 
65 Dopamine Receptors in a Songbird Brain Lubica Kubikova,1,2* Kazuhiro Wada,1,3
 

Summary:  , the D1A, D1B, and D2 receptors were highly expressed in the striatum, the D1D and D3 throughout... to the surrounding regions and developmentally regulated expression that decreased for most receptors during... these studies to determine expression of the specific ...

  

Source: Jarvis, Erich D. - Department of Neurobiology, Duke University

 

Collection: Biology and Medicine

 
66 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  and the expression of its receptor, nuclear receptor coregulators are essential for efficient ste- roid... as GRIP1, TIF2 and NCoA-2) [216,71] and SRC-3 (AIB1, TRAM-1, p/CIP, ACTR and RAC3) [6,194]. The SRC family... transcriptional activation of receptors [159]. In ...

  

Source: Tetel, Marc J. - Department of Biological Sciences, Wellesley College

 

Collection: Biology and Medicine

 
67 Molecular and pharmacological characterization of muscarinic receptors in retinal pigment epithelium: role in light-adaptive
 

Summary:  . We isolated M2 and M5 receptor genes from bluegill and studied their expression. Only M5 was found... characterization of muscarinic receptors in fish and studies of their expression and function in RPE along... with the chick and human M2 receptors respectively. ...

  

Source: García, Dana M. - Department of Biology, Texas State University - San Marcos

 

Collection: Biology and Medicine

 
68 International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors
 

Summary:  isolated by expression cloning (Hollopeter et al., 2001), and P2Y13 and P2Y14 receptors were characterized... couplings can be made in each receptor-expressing cell, as reviewed below. Because single cells... International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
69 Role of delivery and trafficking of d-opioid peptide receptors in opioid
 

Summary:  expression of these receptors. MOP receptors are constitutively expressed on the cell surface. The physical... types of opioid receptor, m-, d- and k-opioid peptide receptors, are expressed in small DRG neurons... in which the ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
70 Antisense Inhibition of 5-Hydroxytryptamine2a Receptor Induces an Antidepressant-Like Effect in Mice
 

Summary:  - doxical that mianserin, a 5-HT2A/2C receptor antagonist with an antidepressant effect also elicits... level of 5-HT that may down-regulate the receptor. In contrast, mianserin, a 5-HT2A/2C receptor... with ritanserin, a ...

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine

 
71 REVIEW ARTICLE Nuclear Receptor Coactivators: Essential Players for Steroid Hormone
 

Summary:  , in addition to the availability of the hormone and the expression of its receptor, nuclear receptor... as GRIP1, TIF2 and NCoA-2) (44, 45) and SRC-3 (AIB1, TRAM-1, p / CIP, ACTR, RAC3) (46, 47). The SRC family... necessary for full transcriptional activation of ...

  

Source: Tetel, Marc J. - Department of Biological Sciences, Wellesley College

 

Collection: Biology and Medicine

 
72 Recombinant Production and Properties of Binding of the Full Set of Mouse Secreted Phospholipases A2 to the Mouse M-Type Receptor
 

Summary:  -type receptor is discussed on the basis of our current knowledge of sPLA2 functions. Secreted phospholipases A2... 2 to the Mouse M-Type Receptor Morgane Rouault,,§ Catherine Le Calvez,,§ Eric Boilard,,§ Fanny... ReceiVed NoVember 29, 2006 ABSTRACT: To date, 12 secreted phospholipases ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
73 ABSTRACT The concept of a purinergic sig-nalling system, using purine nucleotides and
 

Summary:  were due to indirect action via P1 receptors. Four subtypes of P2 receptors were cloned, namely A1, A2A... , cerebralischaemia, sleep apnoea, pain and inflammation32. A2A receptor antagonists are being investigated... , ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
74 Function and structure in glycine receptors and some of their relatives
 

Summary:  rates [25]. The opening rate b2 is also somewhat increased, and the shutting rate a2 is decreased... in patients with this mutation [28]. TRENDS in Neurosciences R AR (a) A2R 2k+1 k+2 k-1 2 2k-2 1 1 2 AR* A2R* R... -AR AR-R R-AR* R-R 52 000 1860 80 000 369 3.9 10400 ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
75 Provided for non-commercial research and educational use only. Not for reproduction, distribution or commercial use.
 

Summary:  ­13], engineered expressed monoaminergic turkey 1AR [14], engineered expressed human A2A adenosine receptor [15... pathway for diffusible ligands. The structure of an engi- neered human A2A adenosine receptor in complex... ...

  

Source: Sakmar, Thomas P. - Laboratory of Molecular Biology and Biochemistry, Rockefeller University

 

Collection: Biology and Medicine

 
76 *National Institute of Child Health and Human
 

Summary:  - prises the A1 , A2A , A2B and A3 adenosine receptors, which were identified by convergent data from... and locomotor depressant effects85 . The most well-known signal transduction mecha- nism for A2A receptors... is the ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
77 Pharmacological characterization of serotonin receptor subtypes modulating primary aerent input to deep dorsal horn neurons in
 

Summary:  (see Zifa & Fillion, 1992; Hoyer et al., 1994) and also the low expression of 5-HT2A/2C receptors... used were; NAN-190 or WAY-100635, 5-HT1A receptor antagonists; ketanserin, a 5-HT2A/2C receptor... , application of the ...

  

Source: Hochman, Shawn - Department of Physiology, Emory University

 

Collection: Biology and Medicine

 
78 5-HT Receptors and the Neuromodulatory Control of
 

Summary:  the low expression of 5-HT2A/2C receptors in the dorsal horn (see Section 2.2.2). 3.2 5-HT1A/1B RECEPTORS... A/7 receptors, there was no evidence to support tonic activation of the 5-HT2A/2C receptor, ...

  

Source: Hochman, Shawn - Department of Physiology, Emory University

 

Collection: Biology and Medicine

 
79 G protein-coupled receptors (GPCRs) are the largest family of transmembrane proteins in vertebrates and they
 

Summary:  -specific protein 1; T2R, taste receptor type 2; TM, transmembrane; TXA2R, thromboxane A2 receptor; USP4, ubiquitin... by transfection or viral infection, to express the gene. are downstream of receptor activation, including 2 AR... , their ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
80 Behaioural Pharmacology 2001; 00:1 10 REVIEW Serotonin receptors in mood disorders: a combined1A
 

Summary:  receptors. These may include 5-HT , 5-HT and 5-HT receptors, since2A 2C 3 selective antagonists acting... expression profiling to attempt to untangle the distinct roles for this receptor in particular brain regions... ., 1998 . However, the com- plexity of the ...

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine


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81 Characterization of Interactions between Death Receptor 5 and its Ligand TRAIL
 

Summary:  of TRAIL to its target receptors leads to increased expression of TRAIL, thus causing auto... 103 Chapter 5 Characterization of Interactions between Death Receptor 5 and its Ligand TRAIL #12... was the result of binding to membrane bound receptors, of which two different types exist[8]. As was the case

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
82 List of publications List of publications
 

Summary:  of ASBT (SLC10A2) by VDR, FXR and GR ligands in rat and human intestine and liver (under preparation... Receptors, AAPS-2008, Altanta, GA, USA. · Khan AA, Dragt BS and Groothuis GMM: Regulation of VDR expression... ). Expression and regulation of the bile acid transporter, OST-OST in rat ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
83 BRADSHAW 978-0-12-374145-5 00388 Multi-Pass Receptors
 

Summary:  ] Expressed engineered human A2A adenosine receptor 3EML 2.6 Jaakola et al. [15] t0010t0010 ch023.indd 152ch... - neered human A2A adenosine receptor in complex with the subtype specific antagonist ZM241385 provides... a number of additional ...

  

Source: Sakmar, Thomas P. - Laboratory of Molecular Biology and Biochemistry, Rockefeller University

 

Collection: Biology and Medicine

 
84 International Union of Pharmacology. XXXV. The Glucagon Receptor Family
 

Summary:  55:167­194, 2003 Printed in U.S.A 167 #12;E. Glucagon-like peptide-2 receptor expression and function... . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 E. Expression and regulation of the growth hormone-releasing hormone receptor... Systems Recombinant secretin receptors ...

  

Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
85 Perspectives in Pharmacology P2 Purinergic Receptors: Modulation of Cell Function and
 

Summary:  this response. AMP gives rise to adenosine, which acti- vates the various P1 receptors (A1, A2A, A2B, A3... of splice variants and approximately 11 P2Y receptors have been cloned and expressed (Ralevic and Burnstock... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
86 UCB Pharma research day--25 October 2007 `Glia-neuron interactions and purinergic receptors
 

Summary:  . In the early 1990s, P1 and P2 receptors were cloned and characterised: four P1 receptor subtypes (A1, A2A, A2B... and epilepsy is still unclear. Not only do glial cells express various ion channels and receptors... /6 and ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
87 THEJOURNALOF BIOLOG~CAL CHEMISTRY c ) 1991by The American Society for Biochemistry and MolecularBiology, Inc.
 

Summary:  -conotoxin receptor solubilized from brain membranes whereas specific antibodies against the al, a2,and y subunits did... Abs, two anti-a2, and two anti-y subunit poly- clonal antibodies did not react with the receptor. Fig. 1... - search Bldg., Iowa City, IA 52242. ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
88 Research Signpost 37/661 (2), Fort P.O., Trivandrum-695 023, Kerala, India
 

Summary:  the pig ureter, while intravesical adenosine via A2B receptors on smooth muscle [6]. ATP and adenosine... during distension of the ureter has been shown to act on P2X3 receptors expressed on suburothelial... [2,3]). There is widespread expression of these ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
89 Original Paper Cells Tissues Organs 2002;172:255264
 

Summary:  . 1a, 2), and in endothelial cells of thymic blood vessels (fig. 3, 4). In T cells, P2Y2 receptor m... RNA was primarily localised in the cytoplasm (fig. 1a, 2a, b). The cytoplasmic expression of transcripts also... . Dividing T cells also expressed ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
90 Bulletin of Mathematical Biology (2008) 70: 15251569 DOI 10.1007/s11538-008-9321-6
 

Summary:  of the system was defined as A(t) = a1R(t) + a2X(t) + a3Y(t) + a4D(t), (1) #12;1534 Tindall et al. Fig. 6... , the intracellular phosphorylation cascade, membrane receptor clus- tering, and spatial modeling of intracellular... gradient along their own length, bacteria use a system of membrane receptors and ...

  

Source: Maini, Philip K. - Centre for Mathematical Biology & Mathematical Institute, University of Oxford

 

Collection: Mathematics ; Biology and Medicine

 
91 Regulation of Neurotransmitter Release by Metabotropic Glutamate Receptors
 

Summary:  (IC50 values) at mGlu receptor clones (expressed in M) Compound Group I Group II Group III mGlu1 mGlu5... receptors are highly expressed in glial cells (Ohishi et al., 1993, 1994; Mineff and Valtschanoff, 1999... ), as the expression of presynaptic mGlu receptors can ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
92 Introduction In 1987, a receptor was identified in a search for tyrosine
 

Summary:  of Eph expression The highly dynamic and complex spatiotemporal expression patterns of the Eph receptors... regions of the central nervous system, Eph receptors and ephrins show complementary patterns of expression... the Ras­MAP-kinase pathway (Kim et al., 2002). Likewise, ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
93 PERSPECTIVE Orphan nuclear receptors--new ligands
 

Summary:  steroid receptors. Prominently inducible members of the rodent P450 3A gene family (CYP3A1, CYP3A2, CYP3A... (Kliewer et al. 1998). In this view, PXR induces the expression of genes such as CYP3A1, CYP3A2, CYP3A23... to and activate tran- scription through a ...

  

Source: Blumberg, Bruce - Department of Developmental and Cell Biology, University of California, Irvine

 

Collection: Biology and Medicine

 
94 JOURNAL OF CELLULAR PHYSIOLOGY 200:309317 (2004) Significance of N-Methyl-D-Aspartate (NMDA)
 

Summary:  and Taichman, 1994). These suprabasal cells are also found to express atypical integrins (a2, a3, a6, and b1... receptors in human keratinocytes. NMDA receptor expression strongly reflects the degree of cell... -to-cell contact. Wounding polarizes the ...

  

Source: Bear, Mark - Picower Institute for Learning and Memory & Department of Brain and Cognitive Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
95 Bovine Papillomavirus E5 Protein Induces the Formation of Signal Transduction Complexes Containing Dimeric Activated
 

Summary:  to downstream signaling substrates (25, 28). Moreover, cells that normally do not express the PDGF receptor... /ml hygromy- cin. For the experiment shown in Fig. 3, Ba/F3 cells expressing the wild-type human PDGF receptor... engineered to co-express the full-length wild-type human PDGF ...

  

Source: DiMaio, Daniel - Departments of Genetics & Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
96 Oligomeric forms of G protein-coupled receptors (GPCRs)
 

Summary:  found in crystals of engineered human b2-adrenergic receptor [29] and an engineered human A2A adenosine... ­1265 30 Jaakola, V.P. et al. (2008) The 2.6 angstrom crystal structure of a human A2A adenosine receptor... GPCRs because the area occupied by a single GPCR on ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
97 Eph receptor tyrosine kinases and ephrins have been identified in organisms ranging from sponges to flies and worms to chick,
 

Summary:  controlling the graded expression of ephrin-A2 and ephrin-A5 (for review, see [55]). The single Drosophila Eph... - ically organized retinal projections contain a conserved module with graded ephrin-A2/A5 expression. 43... , -galactosidases, and so on. However, as Eph ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
98 NPY signaling through Y1 receptors modulates thalamic oscillations
 

Summary:  of the three Y receptor agonists. Fig. 2A2, B2 and C2 shows representative sweeps within these recordings... ). Effects of the Y1 receptor agonist Leu31Pro34NPY (A1 and A2), the Y2 receptor agonist PYY3­36 (B1 and B2... capsule ...

  

Source: Huguenard, John R. - Department of Neurology and Neurological Sciences, Stanford University

 

Collection: Biology and Medicine

 
99 For personal use only. Not to be reproduced or distributed without permission from Prous Science. Drug News Perspect 16(3), April 2003 2003 Prous Science CCC: 02140934/2003 133
 

Summary:  and vasorelaxant A2 receptors are also expressed on vas- cular smooth muscle.1,21 Some vascu- LOOKING AHEAD All... vasorelaxant P2Y receptors (P2Y1-like).22-26 P2Y and A2 receptors expressed on smooth ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
100 Modulation of steroid action in the central and peripheral nervous systems by nuclear receptor
 

Summary:  . Thus, in addition to the availability of the hormone and its receptor, the expression of nuclear... will discuss the significance of nuclear receptor coactivators in modulating steroid-dependent gene expression... ., 1995). SRC-1 is a member of a larger family of p160 coactivators that includes SRC-2 ...

  

Source: Tetel, Marc J. - Department of Biological Sciences, Wellesley College

 

Collection: Biology and Medicine


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