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Sample search results for: a2 inhibition protects

Page:   2  3  4  5 
 
1 cGMP signalling in pre-and post-conditioning: the role of mitochondria
 

Summary:  that adenosine receptors must be repopulated at reperfusion for IPC to protect the heart. Oddly a Gs-coupled A2... IPC's protec- tion in a nai¨ve heart. Furthermore, an A2b-selective blocker aborted protection from... the phorbol ester. Conver- sely, the ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
2 110175 Acetyl-Pepstatin Aspartic/Reversible 50 200 nM Soluble in 50% acetic acid. Ki for HIV-1 and 1 mg /1.553 ml of Dilute 1:1000 to M.W. 643.8 Inhibits HIV-1 and HIV-2 proteases. HIV-2 proteases is 20 nM and 5 nM, respectively, 50% acetic acid = 1 mM o
 

Summary:  , cathepsin B, and trypsin. 441251 a2-Macroglobulin, Broad Range/Irreversible Use at Aqueous stock solutions... and 1 mg /1.553 ml of Dilute 1:1000 to M.W. 643.8 Inhibits HIV-1 and HIV-2 proteases. HIV-2 proteases... Use at 1 mM M.W. 239.5 Inhibits trypsin, chymotrypsin, plasmin, thrombin, at 4°C, pH 7. Will ...

  

Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem

 

Collection: Biotechnology ; Biology and Medicine

 
3 Roche Molecular Biochemicals The Complete Guide for
 

Summary:  high stability and irreversible inhibition mechanism, protein solutions are protected throughout total... . Pefabloc SC inhibits proteinase K, and protects the stability of restriction enzymes used for further DNA... Deliver consistent doses of protease inhibition. q All components ...

  

Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem

 

Collection: Biotechnology ; Biology and Medicine

 
4 110175 Acetyl-Pepstatin Aspartic/Reversible 50 200 nM Soluble in 50% acetic acid. Ki for HIV-1 and 1 mg /1.553 ml of Dilute 1:1000 to M.W. 643.8 Inhibits HIV-1 and HIV-2 proteases. HIV-2 proteases is 20 nM and 5 nM, respectively, 50% acetic acid = 1 mM o
 

Summary:  . 441251 a2-Macroglobulin, Broad Range/Irreversible Use at Aqueous stock solutions are stable for 6 months... and 1 mg /1.553 ml of Dilute 1:1000 to M.W. 643.8 Inhibits HIV-1 and HIV-2 proteases. HIV-2 proteases... Use at 1 mM or less. Hydrochloride Inhibits trypsin, chymotrypsin, plasmin, thrombin, at 4°C, ...

  

Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem

 

Collection: Biotechnology ; Biology and Medicine

 
5 Nature Macmillan Publishers Ltd 1997 membrane-anchored syntaxin 1A directly modulates N-type cal-
 

Summary:  or indirectly inhibit CED-3 by means of a protective mechanism similar to that used by mammalian Bcl-2... -9 to inhibit cell death in C. elegans by using an in vivo cell-death protection assay2,9 . Briefly... distinct domains that can each inhibit cell death and which are both required ...

  

Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
6 Role of -Subunit VISIT-DG Sequence Residues Ser-347 and Gly-351 in the Catalytic Sites of Escherichia coli ATP Synthase*
 

Summary:  . (20) in which the protection afforded by Pi against inhibition of ATPase activ- ity induced... was as in Ref. 43. Inhibition of ATPase Activity by NBD-Cl and Protection by MgADP or Pi--NBD-Cl was prepared... (45, 46). Protection against NBD-Cl Inhibition of ATPase ...

  

Source: Zulfiqar Ahmad - Department of Biological Sciences, East Tennessee State University

 

Collection: Biology and Medicine

 
7 Copyright 1999 Psychonomic Society, Inc. 346 Animal Learning & Behavior
 

Summary:  thought to result from conditioned inhibition acquired by the CS during preexposure, which impaired... conditioned inhibition is disrupted by preexposure to the overshadowed inhibitor AARON P. BLAISDELL, HERNÁN I... of conditioned inhibition treatment was examined. Blais- dell, Bristol, Gunther, and Miller (1998) have

  

Source: Cook, Robert - Department of Psychology, Tufts University

 

Collection: Biology and Medicine

 
8 ENVIRONMENTAL ENGINEERING SCIENCE Volume 20, Number 3, 2003
 

Summary:  Figure 5. Inhibition of NH4 1 -N oxidation by (a) 2.5 mM EDTA or (b) 0.25 mM EDA in presence of metal... Inhibition by Ethylenediamine-Based Chelating Agents Zhiqiang Hu,1 Kartik Chandran,1, Domenico Grasso,2... Picker Engineering Program Smith College Northampton, MA 01063 ABSTRACT Nitrification ...

  

Source: Smets, Barth F. - Department of Civil and Environmental Engineering, University of Connecticut

 

Collection: Engineering

 
9 ALZHEIMER'S AMYLOID-BETA PEPTIDE INHIBITS SODIUM/CALCIUM EXCHANGE MEASURED IN RAT AND
 

Summary:  ­35 inhibition of Ca2+ content Condition nmol Ca2+ /mg/5 min no addition 4.1 0.7 50 µM aggregated A 25­35,a 2.5 0... ­35 to produce its protective effect. Congo Red has also been reported29 to prevent fibril formation and inhibit... ALZHEIMER'S AMYLOID-BETA PEPTIDE ...

  

Source: Colvin, Robert A.- Department of Biological Sciences, Ohio University

 

Collection: Biology and Medicine

 
10 DOI: 10.1002/cbic.201000442 Mechanisms of Macromolecular Protease Inhibitors
 

Summary:  as a substrate, then utilizes the enzymes' catalytic machinery to trap and inhibit the enzyme. The inhibitor a-2... -macroglobin (a2M) and its relatives are re- sponsible for clearing excess proteases from plasma. Less... an inhibitor than a "protease sponge", ...

  

Source: Craik, Charles S. - Departments of Pharmaceutical Chemistry, Cellular and Molecular Pharmacology & Biochemistry and Biophysics,University of California at San Francisco

 

Collection: Biology and Medicine

 
11 Novel 2-Oxoamide Inhibitors of Human Group IVA Phospholipase A2
 

Summary:  -2191. (23) (a) Yu, L.; Dennis, E. A. Kinetic analysis of the competitive inhibition of phospholipase A2... Novel 2-Oxoamide Inhibitors of Human Group IVA Phospholipase A2 George Kokotos,*, Stavroula... , Greece Received May 8, 2002 Abstract: A novel class of potent human cytosolic phospho- ...

  

Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Biology and Medicine

 
12 JOURNAL OF VIROLOGY, 0022-538X/01/$04.00 0 DOI: 10.1128/JVI.75.17.81588165.2001
 

Summary:  in the inhibition of protein secretion, was tested. We show here that cells infected with 3A-2 mutant virus secrete... inhibition of host protein secretion, because no signif- icant differences between 3A-2- and wild... culture (15). The existence of the ...

  

Source: Kirkegaard, Karla - Department of Microbiology and Immunology, Stanford University

 

Collection: Biology and Medicine

 
13 Biophysical Journal Volume 68 March 1995 936-945 Anesthetics Alter the Physical and Functional Properties of the
 

Summary:  protected against lidocaine-induced inhibition, indicating that electrostatic interactions are essential... was phosphorylated, indicating a protective effect of PLB on halothane-induced inhibition and aggregation... (t) = K (ale-Dit + a2e-4Dit + a3) (7) with a, = 6/ ...

  

Source: Thomas, David D. - Departments of Biochemistry, Molecular Biology, & Biophysics, University of Minnesota

 

Collection: Biology and Medicine

 
14 MHC I-dependent antigen presentation is inhibited by poliovirus protein 3A Stephen B. Deitz, Dana A. Dodd, Stewart Cooper, Peter Parham, and Karla Kirkegaard
 

Summary:  infected with wild-type poliovirus, target cells infected with 3A-2 mutant poliovirus showed no inhibition... of secretion is probably not required for vesicle formation. A cold-sensitive mutation in poliovirus 3A, 3A-2... otherwise indicated. Wild-type Mahoney-type-1 poliovirus and ...

  

Source: Kirkegaard, Karla - Department of Microbiology and Immunology, Stanford University

 

Collection: Biology and Medicine

 
15 CYCLOOXYGENASE INVOLVEMENT IN THROMBOXANE-DEPENDENT CONTRACTION IN RAT MESENTERIC RESISTANCE ARTERIES
 

Summary:  phospholipase A2 inhibition. Measurement of cyclooxygenase derivatives produced by the isolated mesenteric bed... , diclofenac and aspirin were used to inhibit COX activity (1), furegrelate to block TxA2 synthesis (19), SC... finding that U-46619-induced contraction ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
16 Edema Toxin Impairs Anthracidal Phospholipase A2 Expression by Alveolar
 

Summary:  by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein... ) High bactericidal efficiency of type iia phospholipase A2 against Bacillus anthracis and inhibition... , Chignard M, Mock ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
17 Many of the enzymes, receptors and eicosanoid metabo-lites of the arachidonate cascade (FIG. 1) are key thera-
 

Summary:  of thrombus formation, as prostaglandin I2 (PGI2) and thromboxane A2 (TXA2) regulate the interaction between... EHIs, resulting in decreased PGE2 levels while maintaining the PGI2/thromboxane A2 ratio (PGI2/TXA2 ratio... diminishing their beneficial cardiovascular properties20,21 . ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
18 Cardiovascular, Pulmonary and Renal Pathology Soluble Epoxide Inhibition Is Protective Against
 

Summary:  Cardiovascular, Pulmonary and Renal Pathology Soluble Epoxide Inhibition Is Protective Against... of both WKY and SHRSP rats. Hence, we conclude that chronic SEH inhibition protects against cerebral... to the cerebral protective effects of SEH inhibition during states ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
19 Role of Asn-243 in the Phosphate-binding Subdomain of Catalytic Sites of Escherichia coli F1-ATPase*
 

Summary:  of Pi. In wild type (Fig. 7A), 2.5 and 10 mM Pi had clear effects, protecting from inhibition by NBD- Cl... - trobenzo-2-oxa-1,3-diazole inhibited this activity less po- tently than in wild type and Pi protected from... from NBD-Cl inhibition by ...

  

Source: Zulfiqar Ahmad - Department of Biological Sciences, East Tennessee State University

 

Collection: Biology and Medicine

 
20 Environmental Toxicology and Chemistry, Vol. 25, No. 7, pp. 17461756, 2006 Printed in the USA
 

Summary:  : Technological challenges. En- viron Sci Technol 28:266A­276A. 2. U.S. Environmental Protection Agency... .5 0.035 1B 7.3 0.36 0.035 2A 2.2 0.91 0.040 2B 10 0.86 0.040 3A 0.77 0.31 0.23 0.084 0.47 0.030 0... multisubstrate biodegradation kinetic models: One that accounts for competitive ...

  

Source: Peters, Catherine A. - Department of Civil and Environmental Engineering, Princeton University

 

Collection: Environmental Sciences and Ecology


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21 J Mol Cell Cardiol 32, 677695 (2000) doi:10.1006/jmcc.2000.1111, available online at http://www.idealibrary.com on
 

Summary:  -related peptide, adenosine (adenosine A2 re- ceptor subtype), prostacyclin and -adrenoceptorciting possibility... of arrhythmogenesis. Another school of KATP openers would exert a cardioplegic action and protect by inhibiting energy... was inhibited by KATP openers, al- though it was ...

  

Source: Garlid, Keith - Department of Biology, Portland State University

 

Collection: Biology and Medicine

 
22 Bromoenol Lactone Inhibits Magnesium-dependent Phosphatidate Phosphohydrolase and Blocks Triacylglycerol Biosynthesis in
 

Summary:  - pholipase A2 (PLA2) inhibitor that possesses greater than 1000-fold selectivity for inhibition of Ca2 -inde... . Current evidence indicates that phospholipase A2 (PLA2)1 is a major mediator of agonist... , University of California, La Jolla, CA 92093-0601. 1 The abbreviations used are: ...

  

Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Biology and Medicine

 
23 Chemistry and Biology of Ramoplanin: A Lipoglycodepsipeptide with Potent Antibiotic Activity
 

Summary:  -threo- -Hydroxyasparagine) 463 6.2. Total Synthesis of the Ramoplanin A2 and Ramoplanose Aglycon 464 6.3. Total Synthesis... salient features will be repeated here.15 Ramoplanin factors A1 (1), A2 (2), and A3 (3) were discovered... ) based on work by Figure 2. (a) Structures of the ramoplanins. (b) Structures ...

  

Source: Walker, Suzanne - Departments of Microbiology and Molecular Genetics & Chemistry and Chemical Biology, Harvard University

 

Collection: Chemistry ; Biology and Medicine

 
24 Pharmacological Targeting of the Mitochondrial Phosphatase Dahlia Doughty-Shenton, James D. Joseph, Ji Zhang, David J. Pagliarini, Youngjun Kim,
 

Summary:  of the phospholipase B of Cryptococcus neoformans, some inhibition of purified, recombinant porcine phospholipase A2... that inhibits response by 50% of 1.08 M. A related dibiguanide ana- log, chlorhexidine dihydrochloride, also... significantly inhibited PTPMT1, albeit with lower ...

  

Source: Pagliarini, David J. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
25 Cardioprotective Effects of Mineralocorticoid Receptor Antagonists at Reperfusion
 

Summary:  '-nucleotidase (CD73), as well as adenosine A2b receptor knock-out mice could no longer be protected, suggesting... -out (ko) or A2b adenosine receptor (AR) ko mice. In both knock-out animals, CAN's protection was blunted... , suggesting a role for extracellular ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
26 Inhibition of Microsomal Epoxide Hydrolases by Ureas, Amides, and Amines
 

Summary:  EH, microsomal EH, four P450s (1A, 2B, 3A, and 4A1), and a CoA-oxidase from rat liver were evaluated... Inhibition of Microsomal Epoxide Hydrolases by Ureas, Amides, and Amines Christophe Morisseau, John... . To provide new tools for studying the function of mEH, inhibition of this enzyme was investigated. ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
27 Journal of Experimental Psychology: Human Perception and Performance
 

Summary:  is a signal to inhibit the response to the letter (the slopping paradigm). These effects were replicated under... , in which the tone required an overt response, like the dual-task paradigm, but was also a signal to inhibit... suffered interference only if subjects failed to inhibit the concurrent response to the letter; ...

  

Source: Palmeri, Thomas - Department of Psychology, Vanderbilt University

 

Collection: Biology and Medicine

 
28 Bruce N. Cronstein, MD You Are Not Arthur Conan Doyle
 

Summary:  ), the fibroblasts of the liver, and A2A knockout mice are protected from developing hepatic... A2A receptors in fibrosis in tissues outside of the skin is less clear... . Prior studies have demonstrated that adenosine ...

  

Source: Wang, Da-Neng - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University

 

Collection: Biology and Medicine

 
29 Information transfer in metabolic pathways Effects of irreversible steps in computer models
 

Summary:  for E2 was calculated from Eqn (2) of the text, with Keq ¼ 5, V ¼ 120, a1 ; s1, a2 ; [ATP] ¼ 8 (constant... Eqn (1) may be generalized as follows: v ¼ VÁ a1a2 Km1Km2 Á 1 ÿ p1p2 Keqa1a2 1 þ a1 Km1 þ p1 Kp1 1... þ ...

  

Source: Centre National de la Recherche Scientifique, Groupe de Laboratoires de Marseille du CNRS, Enzyme Kinetics and Control Analysis Group

 

Collection: Biotechnology ; Biology and Medicine

 
30 JOURNAL OF BACTERIOLOGY, 0021-9193/01/$04.00 0 DOI: 10.1128/JB.183.14.42444250.2001
 

Summary:  in the presence of various levels of acetyl phosphate and a fixed level of CoA (2 mM). Data were plotted as 1/v... phosphate to protect the enzyme from 2,3-butanedione inhibition suggest that acetyl phosphate is bound... modification of the wild-type enzyme by 2,3-butanedione and substrate ...

  

Source: Ferry, James G. - Department of Biochemistry and Molecular Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
31 Cellular/Molecular The Micromolar Zinc-Binding Domain on the NMDA
 

Summary:  (in M): 0.17 for V42A, 2.6 for G43A, 2.8 for E47A, 5.7 for D101A, 3.7 for T103A, 4.9 for H127A, 2... .7 for Y175A, 2.5 for F182A, 2.6 for T233A, and 3.1 for D265A. Thus, the two muta- ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
32 Uncoupling of the Signaling and Caspase-inhibitory Properties of X-linked Inhibitor of Apoptosis*
 

Summary:  and Omi/HtrA2 (25­30). These molecules are released from mitochondria into the cytoplasm during apoptosis... is mutually exclusive (17, 23, 32). Thus, Smac/DIABLO and Omi/HtrA2 are negative regulators of XIAP... that function to release XIAP from caspases; in the case of ...

  

Source: Burstein, Ezra - Cellular and Molecular Biology Program, University of Michigan

 

Collection: Biology and Medicine

 
33 Eur. J. Biochem. 267, 17611769 (2000) q FEBS 2000 Effects of cadmium on manganese peroxidase
 

Summary:  of bee venom phos- pholipase A2. Biochemistry 24, 3180±3188. 46. Yu, B.Z., Berg, O.G. & Jain, M.K. (1993... ) The divalent cation is obligatory for the binding of ligands to the catalytic site of secreted phospholipase A2... Competitive inhibition of MnII oxidation and thermal ...

  

Source: Youngs, Heather - Department of Biological Sciences, Michigan Technological University

 

Collection: Biology and Medicine

 
34 Secretariat of the Convention on
 

Summary:  FOR CONSIDERATION IN THE PLANNING, ESTABLISHMENT AND MANAGEMENT OF PROTECTED AREA SITES AND NETWORKS #12... ;BIODIVERSITY ISSUES FOR CONSIDERATION IN THE PLANNING, ESTABLISHMENT AND MANAGEMENT OF PROTECTED AREA SITES... for consideration in the planning, establishment and management of protected area sites and networks. Montreal, ...

  

Source: Lebreton, Jean-Dominique - Centre d’Ecologie Fonctionnelle et Evolutive

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
35 Carcinogenesis vol.28 no.5 pp.10521057, 2007 doi:10.1093/carcin/bgl248
 

Summary:  CYP1A1, -1A2 and -1B1, indicating that compound 343 directly inhibits CYP en- zymes. These results... of CYP1A1, -1A2 and -1B1 induced by both carcinogens were inhibited by compound 343 in a concentration... of CYP1A1, -1A2 ...

  

Source: Hergenrother, Paul J. - Department of Chemistry, University of Illinois at Urbana-Champaign

 

Collection: Chemistry

 
36 Adenosine-Mediated Presynaptic Modulation of Glutamatergic Transmission in the Laterodorsal Tegmentum
 

Summary:  , in the same cells, adenosine inhibited the evEPSC by 41.8 4.4%. These findings suggest that A2 receptor... nM) but not by the A2 agonist N6- [2-(3,5-dimethoxyphenyl)-2-(methylphenyl)-ethyl]-adenosine (10 n... ­1000 nM at A2 receptors) (Bruns et ...

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
37 THE JOURNALOF BIOLOGICALCHEMISTRY 01986by The American Society of Biological Chemists, he.
 

Summary:  conditions which protect the antiporter from inhibition byDCCD also prevent labeling of the 82... protects the antiporter from DCCD inhibition and binding (5). To facili- tate quantitative comparison... of inhibition and protection, we have examined the dose response ...

  

Source: Garlid, Keith - Department of Biology, Portland State University

 

Collection: Biology and Medicine

 
38 Resveratrol : natural properties against atherosclerosis, associated pro-inflammatory effects and aging
 

Summary:  ] (figure 5). Resveratrol inhibits ET-1 surproduction and cytosolic phospholipase A2 (PLA2) activity... signalling pathways appears to protect against VSMC contraction mediated by the ETA-receptor. The inhibition... is accompanied by the release of thromboxane ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
39 Review article Cardioprotective signaling to mitochondria
 

Summary:  protection (bradykinin, IPC, and postconditioning) is inhibited by KT5823, and we conclude that GPCR... not block protection by ouabain [36]. Activity of the ouabain signalosome is inhibited by preincubation... of protection occurred because mitoKATP-dependent ROS was scavenged and ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
40 Copyright Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited. Inhibition of the soluble epoxide hydrolase attenuates
 

Summary:  -mediated protection against the inflammation induced by monocrotaline. Conclusion sEH inhibition reduces pulmonary... , and while leukotrienes and thromboxane A2 can promote the development of pul- monary hypertension in certain... . Inhibition of the soluble epoxide hydrolase attenuates ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology


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41 Vol. 275, No. 3 Printed in U.S.A.
 

Summary:  - five to inhibition (IC50 0.4 tM), NR1A/2B and 2C receptors had intermediate sensitivity (IC50 1-2 p... .M) and NR1A/2D receptors were least sensitive to inhibition (IC50 -8 p.M). Slopes for the inhibition curves... ). This occurred between NRLA/2C ...

  

Source: Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
42 Nucleic Acids Research, 2007, 18 doi:10.1093/nar/gkm1088
 

Summary:  , with their multiple Arg side chains, could also mimic the conserved Arg residues in the a2-helix of the bacterial RPP... Nucleic Acids Research, 2007, 1­8 doi:10.1093/nar/gkm1088 Studies on the mechanism of inhibition... more potent than neomycin B in inhibiting bacterial RNase P, we synthesized ...

  

Source: Gopalan, Venkat - Departments of Biochemistry & Plant Biology, Ohio State University

 

Collection: Biotechnology ; Biology and Medicine

 
43 Corrosion Protection due to Bacteria /Metal Interactions E. Kus1, K. H. Nealson2 and F. Mansfeld1
 

Summary:  can actually protect them from corrosion (microbiologically influenced corrosion inhibition (MICI)) [1... Corrosion Protection due to Bacteria /Metal Interactions E. Kus1, K. H. Nealson2 and F. Mansfeld1 1... that MR-1 provided excellent corrosion protection for all materials. EPI and SEM studies revealed

  

Source: Southern California, University of - Collaboratory for Advanced Computing and Simulations (CACS)

 

Collection: Engineering ; Computer Technologies and Information Sciences

 
44 Vascular Biology, Atherosclerosis and Endothelium Biology Overexpression of Bcl-2 in Vascular Endothelium
 

Summary:  and inhibition of phospholipase A2 activation.72,73 Possible molecular mechanisms for cellular protection in... in this model, and both can be inhibited by protecting the endothelium via Bcl-2 overexpression in endothelial... and activation of phospholipase ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
45 Edward A. Dennis Publications -1 -Updated 6-29-10 EDWARD A. DENNIS
 

Summary:  inhibition of cobra venom phospholipase A2 and comparison with other phospholipases. J Biol Chem, 260, 11099... , Dennis EA (1985) Cobra venom phospholipase A2 inhibition by manoalide: a novel type of phospholipase... ) The inhibition of ...

  

Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Biology and Medicine

 
46 doi:10.1152/ajpendo.00710.2010 300:E691-E698, 2011. First published 25 January 2011;Am J Physiol Endocrinol Metab
 

Summary:  in the present study in female SHR kidney. Renal CYP4A2 mRNA levels and 20-HETE formation increase more in young... epoxide hydrolase inhibition protects the kidney from hypertension-induced dam- age. J Am Soc Nephrol 15... that perinatal inhibition of soluble epoxide hydrolase (SEH), ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
47 Kinetic and Inhibition Studies for the Aerobic Cometabolism of
 

Summary:  Kinetic and Inhibition Studies for the Aerobic Cometabolism of 1,1,1-Trichloroethane, 1... 2001; accepted 30 April 2002 DOI: 10.1002/bit.10397 Abstract: Batch kinetic and inhibition studies were... to lowest was 1,1-DCA (19 µM), butane (19 µM), 1,1,1-TCA (12 µM) and 1,1-DCE (1.5 µM). The inhibition types

  

Source: Semprini, Lewis - School of Chemical, Biological, and Environmental Engineering, Oregon State University

 

Collection: Environmental Management and Restoration Technologies ; Environmental Sciences and Ecology

 
48 EB 2004 SYMPOSIUM Cold Ischemic Organ Preservation: Lessons from Natural Systems
 

Summary:  of u-PA and t-PA or at the level of plasmin inhibition by SERPINF2 (a2-antiplasmin).27 Both... Plasminogen activator inhibitor 1 Kidney Inhibits u-PA, t-PA, thrombin, acrosin, factor XIa SERPINF2 a2... been reported previously: the up-regulation in liver and ex- port ...

  

Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
49 ______________________________________________________Summary Cannabis sativa has been used by humanity as a source of weaving material as
 

Summary:  by CP55,940. This release was fully inhibited by the CB1-antagonist SR141716A, the phospholipase A2 (PLA... downstream of the CB1-receptor, phospholipase A2 and MAP kinases. The non-selective Ca2+ -antagonists La3... acid was unclear, since the phospholipase ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
50 *Neuroscience Training Program, University of Wisconsin School of Medicine and Public Health, Waisman Center, Madison, Wisconsin, USA
 

Summary:  kDa, illustrated with the classical ubiq- uintinated smear in the 37­250 kDa range in Fig. 1a); 2 h... ablation of NKCC1 had similar protective effects in NKCC1)/) neurons (Fig. 2f). Moreover, inhibition... . 3a); 2 h OGD resulted in increased Ca2+ loading into ER ...

  

Source: Sun, Dandan - Center for Neuroscience, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
51 Inhibitor SourceBookTM Your #1 Resource for Quality Inhibitors
 

Summary:  transition stage. A type cyclins, cyclin A1 and A2, play a role during the S phase. Cdk2/cyclin A complex... ether analog that potently and selectively inhibits Akt (IC50 = 5.0 M). A weak inhibitor... that inhibits the activation of Akt and selected downstream substrates without affecting the phosphorylation

  

Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem

 

Collection: Biotechnology ; Biology and Medicine

 
52 Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune
 

Summary:  23a2/2 mice intranasally with L. pneumophila. Il23a2/2 mice displayed a significant defect in host... of IL-23 in neutrophil recruitment to sites of infection [19]. The phenotype of Il23a2/2 mice... /mouse) or ExoA (2 mg/mouse) ...

  

Source: Vance,. Russell - Department of Molecular and Cell Biology, University of California at Berkeley

 

Collection: Biology and Medicine

 
53 13928 Biochemistry 1994,33, 13928-13937 Halothane and Cyclopiazonic Acid Modulate Ca-ATPase Oligomeric State and
 

Summary:  partially protected the Ca-ATPase from CPA inhibition when it was added to SR in the presence of CPA. Under... (IU) vs [CPA] @M) for the same data, showing that inhibition is not complete by 1pM CPA. could protect... (CPA +halothane). Table 1: Anisotropy Decay Parametersfor ERITC-LSR at 25 'C" sample ro A1 ...

  

Source: Thomas, David D. - Departments of Biochemistry, Molecular Biology, & Biophysics, University of Minnesota

 

Collection: Biology and Medicine

 
54 PerspectiVe Structural and Functional Basis of Cyclooxygenase Inhibition
 

Summary:  I2 or prostacyclin; oCOX-1, ovine cyclooxygenase-1; TxA2, thromboxane A2. © Copyright 2007... -specific isomerases to prosta- glandins (PGE2, PGD2, PGF2R, PGI2) and thromboxane A2 (TxA2) (Figure 1). COX-1 and COX... ...

  

Source: Marnett, Lawrence J. - Department of Chemistry, Vanderbilt University

 

Collection: Biology and Medicine ; Chemistry

 
55 Sorting out the functional role(s) of peroxisome proliferator-activated receptor-/ (PPAR/) in cell proliferation and cancer
 

Summary:  of PPAR/ caused an increase in COX2 expression thereby increasing PGE2 and cytosolic phosholipase A2 (c... , improving insulin sensitivity, inhibiting inflammation and increasing oxidative myofibers allowing... . However, there is considerable controversy whether PPAR/ stimulates or inhibits cell proliferation

  

Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
56 Coming Soon! SigmaFASTTM Protease Inhibitor Tablet for General Use (Cat. No. S8820)
 

Summary:  Leupeptin Pepstatin A 1,10-Phenanthroline AEBSF, 100 mM E-64, 1.4 mM Pepstatin A, 2.2 mM 1,10-Phenanthroline... 1860 P5726 P2850 Specificity of Inhibition Serine, Cysteine, Aspartic & Metalloproteases Serine... will inhibit) Typically enough for 100 ml of cell lysate, depending on cell type 1 mg of USP ...

  

Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem

 

Collection: Biotechnology ; Biology and Medicine

 
57 Immunity, Vol. 22, 355370, March, 2005, Copyright 2005 by Elsevier Inc. DOI 10.1016/j.immuni.2005.02.004 Granzyme A Induces
 

Summary:  . Superoxide scavengers also block apo- et al., 1997), HtrA2/Omi (Hegde et al., 2002; Martins et ptosis by CTLs... action on mitochondria to in- duce increased ROS and loss of , but not release of chrome c, HtrA2/Omi... probed with antibodies to cytochrome c (Cyt c), the serine protease ...

  

Source: Lieberman, Judy - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
58 Protection by D609 Through Cell-Cycle Regulation After Stroke
 

Summary:  increased PLD activity [17]. D609 (375 µM) did not inhibit TNF-- stimulated phospholipase A2 (PLA2) activity... kinase C PLA2 Phospholipase A2 PLD Phospholipase D PP Protein Phosphatase pRb phospho-Retinoblastoma Rb... by differentially affecting phospholipase ...

  

Source: Epstein, Miles L. - Neuroscience Training Program & Department of Anatomy, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
59 Protection by D609 Through Cell-Cycle Regulation After Stroke
 

Summary:  PLD activity [17]. D609 (375 µM) did not inhibit TNF-- stimulated phospholipase A2 (PLA2) activity [18... A2 PLD Phospholipase D PP Protein Phosphatase pRb phospho-Retinoblastoma Rb Retinoblastoma ROS... by differentially affecting phospholipase ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
60 94:400-414, 2005. First published Mar 2, 2005; doi:10.1152/jn.01065.2004J Neurophysiol Vasant K. Dasika, John A. White, Laurel H. Carney and H. Steven Colburn
 

Summary:  provide inhibitory feedback to the rest of the network. Empirical data suggest that feedback inhibition... , we assess the effects of SON feedback inhibition. Individual cells are specified as modified leaky... inhibition, ITD sensitivity is significantly reduced as input rates are increased. Feedback ...

  

Source: Carney, Laurel H. - Departments of Biomedical Engineering & Neurobiology and Anatomy, University of Rochester

 

Collection: Biology and Medicine


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61 Retrieval-Induced Forgetting in a Multiple-Trace Memory Model Collin Green (cgreen@arc.nasa.gov)
 

Summary:  1 1 0 0 0 0 0 0 0 0 0 0 Category A, Exemplar a2 1 1 1 1 1 0 0 0 0 0 -1 1 1 1 1 -1 1 -1 -1 -1 0 0 0 0... in part through the inhibition of competing irrelevant information, an effect dubbed Re- trieval... mechanism (feature-based inhibition) that is suggested by behavioral data. We then describe our model

  

Source: Kittur, Aniket - Human Computer Interaction Institute, School of Computer Science, Carnegie Mellon University

 

Collection: Computer Technologies and Information Sciences

 
62 Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation
 

Summary:  ­494. Kerr, I.M., Brown, R.E, 1978. pppA2 p5 p5A: an inhibitor of protein synthesis synthesized... and inhibits signaling at or before Jak-1 activation Karen E. Johnson, David M. Knipe Department... ) encodes many mechanisms that inhibit the type I IFN response, including the ICP27-dependent ...

  

Source: Knipe, David M. - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
63 Inhibition of biofilm formation and swarming of Bacillus subtilis by (5Z)-4-bromo-5-(bromomethylene)-
 

Summary:  interface) and A2 (vertical section, i.e. biofilm viewed on edge by compiling Z sections), no furanone; B1... Inhibition of biofilm formation and swarming of Bacillus subtilis by (5Z)-4-bromo-5-(bromomethylene... )-furanone (furanone) of the marine alga Delisea pulchra was synthesized, and its inhibition of ...

  

Source: Wood, Thomas K. - Department of Chemical Engineering, Texas A&M University

 

Collection: Environmental Sciences and Ecology

 
64 Chemistry & Biology 13, 117122, February 2006 2006 Elsevier Ltd All rights reserved DOI 10.1016/j.chembiol.2005.12.007 Brief CommunicationNative Chemical Ligation in
 

Summary:  140 A° 2 / partner), which is paradoxical to the apparent strength of the inhibition. Finally... .chembiol.2005.12.007 Brief CommunicationNative Chemical Ligation in Covalent Caspase Inhibition by p35 Miao Lu,1... of Cornell University New York, New York 10021 Summary Wide-spectrum caspase ...

  

Source: Wu, Hao - Department of Biochemistry, Cornell University

 

Collection: Biology and Medicine

 
65 Cell Death Differ . Author manuscript Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the
 

Summary:  -Smac/DIABLO and anti-Omi/HtrA2 were respectively from Molecular probes (Invitrogen, Cergy Pontoise, France), Proscience... regarding their potential to inhibit TRAIL-induced apoptosis. We show here that TRAIL-R4, expressed either... endogenously or ectopically, inhibits TRAIL induced apoptosis. ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
66 Abstract. Doxycycline (Dc) has been demonstrated to inhibit cell growth and induce apoptosis in tumor cells,
 

Summary:  . (2002) HtrA2 promotes cell death through its serine protease activity and its ability to antagonize... ., Cilenti L. et al. (2002) Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease... Y., Nakayama H., Takahashi K., Takio K. and Takahashi R. (2001) A serine protease, ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
67 The Molecular Origin and Consequences of Escape from miRNA Regulation by HLA-C Alleles
 

Summary:  , a2, and a short divergent segment of the 30 UTR described below, which we refer to as the RHD (for... to distort our date estimates (the a1, a2, and RHD regions). Taking the divergence of human and chimpanzee... ) is based on 3622 shared nucleotides after elimination of indels and the a1, ...

  

Source: Kidd, Kenneth - Department of Genetics, Yale University

 

Collection: Biology and Medicine

 
68 RESEARCH Open Access Regulation of the Aurora-A gene following
 

Summary:  :205 http://www.molecular-cancer.com/content/9/1/205 Page 3 of 15 #12;A. 2N4N 2N4N 2N4N 2N4N 2N4N 2N4N 2N4N... RESEARCH Open Access Regulation of the Aurora-A gene following topoisomerase I inhibition... lines that Aurora-A expression is downregulated in response to topoisomerase I inhibition. Using

  

Source: Ecole Polytechnique, Centre de mathématiques; Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Mathematics ; Physics

 
69 http://jbx.sagepub.com/ Journal of Biomolecular Screening
 

Summary:  SFL (a 2.6% hit rate) and 8 from the DMSO-soluble OFL (a 2.1% hit rate). In most cases, the observed... analogues selectively inhibit the gram-negative ASADH, whereas some haloacids and substituted aromatic acids... have been found to inhibit only the fungal form of ...

  

Source: Viola, Ronald - Department of Chemistry, University of Toledo

 

Collection: Chemistry ; Biology and Medicine

 
70 Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors
 

Summary:  , it is reasonable to hypothesize that inhibition of this enzyme is the basis of protection by chloram- phenicol... ). The calcium-independent phospholipase A2 (iPLA2) liberates arachidonic acid, and in- hibition of iPLA2 reduces... , which does not inhibit CYP and was not ...

  

Source: Yeager, Mark J. - Department of Cell Biology, Scripps Research Institute

 

Collection: Biology and Medicine

 
71 Significance of the 2-O-sulfo group of L-iduronic acid residues in heparin on the growth inhibition of bovine pulmonary artery smooth muscle cells
 

Summary:  , that is, IdoA 2S, present in the major sequence of HP (Fig. 1A), are important for the antiproliferative... Significance of the 2-O-sulfo group of L-iduronic acid residues in heparin on the growth inhibition... heparin Cell proliferation a b s t r a c t Heparin inhibits the growth of several cell types in ...

  

Source: Linhardt, Robert J. - Center for Biotechnology and Interdisciplinary Studies & Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute

 

Collection: Biotechnology ; Chemistry

 
72 Inhibition of Group IVA Cytosolic Phospholipase A2 by Novel 2-Oxoamides in Vitro, in Cells, and in Vivo
 

Summary:  Inhibition of Group IVA Cytosolic Phospholipase A2 by Novel 2-Oxoamides in Vitro, in Cells... of 1-palmi- Scheme 2. Design of 2-Oxoamide Inhibitors Inhibition of Phospholipase A2 by 2-Oxoamides... . Inhibition of Phospholipase ...

  

Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Biology and Medicine

 
73 Creating a focused corpus of factual outcomes from biomedical experiments
 

Summary:  ameliorate treatment suppress reactivity convert convert is_a effect protection inhibit enhance damage... attenuate hypertension attenuate prevent protect increase improve reduce inhibition attenuate infusion... cysts type phospholipase a2 endothelin-1 transgenic ...

  

Source: Stevens, Robert - School of Computer Science, University of Manchester

 

Collection: Computer Technologies and Information Sciences

 
74 Acetylene Inhibition of Trichloroethene and Vinyl Chloride
 

Summary:  is an extremely potent competitive protecting agent against acetylene inhibition (KD 0.4 µM) (28). The FIGURE 5... Acetylene Inhibition of Trichloroethene and Vinyl Chloride Reductive Dechlorination G E O R G E P O... as intermediates. Batch kinetic studies showed acetylene reversibly inhibited reduction of ...

  

Source: Semprini, Lewis - School of Chemical, Biological, and Environmental Engineering, Oregon State University

 

Collection: Environmental Management and Restoration Technologies ; Environmental Sciences and Ecology

 
75 doi:10.1182/blood-2010-11-321596 Prepublished online March 8, 2011;
 

Summary:  protected it from cleavage by ADAMTS13. We have revealed a novel Ca2 -binding site at the A2 domain of VWF... site was demolished and 4 was completely unfolded (Figure 2B snapshot IV). Ca2 binding protects A2 from... -binding site impair the ...

  

Source: Gräter, Frauke - Institute for Computational Biology, Shanghai Institutes for Biological Sciences

 

Collection: Biology and Medicine

 
76 doi:10.1182/blood-2010-11-321596 Prepublished online March 8, 2011;
 

Summary:  protected it from cleavage by ADAMTS13. We have revealed a novel Ca2 -binding site at the A2 domain of VWF... binding protects A2 from cleavage by ADAMTS13 Because unfolding of the A2 domain is essential... -binding site ...

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
77 Current Drug Targets, 2006, 7, 000-000 1 1389-4501/06 $50.00+.00 2006 Bentham Science Publishers Ltd.
 

Summary:  activation [90,114]. Moreover, by inhibiting phos- pholipase A2, resveratrol decreases the release... activity [21], as well as P450 1A1 and P450 1A2 enzyme activities [14,22] in various cell types... on P450 1A2 via antagonizing AhR properties ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
78 The evolution of contact-dependent inhibition in non-growing populations of Escherichia coli
 

Summary:  xyl-5 mtl-1 proA2 his-4 argE3 str-31 tsx-33 supE44 recC F-. AB1157DmutS::spc gryA (a derivative of AB... The evolution of contact-dependent inhibition in non-growing populations of Escherichia coli Marc... observed the evolution of strains that appeared to kill or inhibit the growth of the bacteria from where

  

Source: Levin, Bruce R. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
79 Pesticide Biochemistry and Physiology 67, 6371 (2000) doi:10.1006/pest.2000.2475, available online at http://www.idealibrary.com on
 

Summary:  shown in Table 1. Verbutin was the best synergist of P450 1A1, 1A2, and 2B1/2B2 in rat liver within... - recently, of human P450 1A1, 1A2, and 1B1ity to LPR house flies (Table 1). expressed in Escherichia coli... . Physiol. C Pharmacol. family (including human P4501A1, and ...

  

Source: Scott, Jeffrey G. - Department of Entomology, Cornell University

 

Collection: Environmental Sciences and Ecology

 
80 Proc. Nati. Acad. Sci. USA Vol. 83, pp. 1613-1616, March 1986
 

Summary:  , the peptides were desalted on a2.5 x 200cm column ofSephadex G-10 equilibrated in 1% (vol/vol) acetic acid... -structure requirements for inhibition by the heat-stable inhibitor of the cAMP-dependent protein kinase (protein... to inhibition of the latter. The interaction of PKI with C is similar to that of ...

  

Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle

 

Collection: Biology and Medicine


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81 Research Report Aromatic l-amino acid decarboxylase turnover in vivo in
 

Summary:  additional insights into the mechanism of FMDOPA suicide inhibition [5]. AAAD is a tightly associated a2... activity after suicide inhibition. Results showed the AAAD turnover half-life to be about 86 h while total... recovery was estimated to be 16 days after complete inhibition. ...

  

Source: Wisconsin at Madison, University of - Waisman Laboratory for Brain Imaging and Behavior

 

Collection: Biology and Medicine

 
82 DIVISION S-3-NOTES HYDROLOGIC TRACER EFFECTS ON SOIL
 

Summary:  of different tracers. Control Br- ci- PFBA Mineralization Nitrification 7.7 (1.5)tat 3.2 (1.2)a 2.5 (0.6)b 0... .2 (0.01)b -id -i ------ 1.9 (0.2)b 0.2 (0.1)b 9.6 (0.6)a 2.2 (1.5)a t Values are means with standard... and Br ~ inhibited all activities other than denitrification and PFBA ...

  

Source: Gold, Art - Department of Natural Resources Science, University of Rhode Island

 

Collection: Environmental Sciences and Ecology

 
83 Ischemic Cell Death in Brain Neurons PETER LIPTON
 

Summary:  . Altered membrane transport properties 1462 B. Mitochondrial damage 1463 C. Global inhibition of protein... inhibition (and subsequent reactivation) of electron transport, decreased ATP, decreased pH, increased cell... com- plete and permanent inhibition of energy metabolism. That would occur because of the inability

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
84 State-dependent Inhibition of the Mitochondrial KATP Channel by Glyburide and 5-Hydroxydecanoate*
 

Summary:  State-dependent Inhibition of the Mitochondrial KATP Channel by Glyburide and 5-Hydroxydecanoate... -HD (K1/2 values 45­75 M) inhibited specific, mitoKATP-mediated K flux in both heart and liver... pretreatment with K channel openers (KCO) or pre- conditioning with a brief period of ischemia protects

  

Source: Garlid, Keith - Department of Biology, Portland State University

 

Collection: Biology and Medicine

 
85 ABBREVIATIONS: NMDA, N-methyl-D-aspartic acid; ACPD, 1-aminocyclopentane-1 ,3-dicarboxylic acid; AMPA,a-amino-3-hydroxy-5-methyli-soxazole-4-propionic acid; BAPTA, 1 ,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid; DMSO, dimethylsulfoxide; DNQX, 6
 

Summary:  ). Slopes of inhibition curves ranged between - 1.5 and -0.94. NR1A/2A gave slightly higher values... . In these experiments all antag- onism was consistent with the simple competitive model except for inhibition of NR1A/2A... in inhibitory mechanism. It should be ...

  

Source: Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
86 JOURNALOF NEUROPHYSIOLOGY Vol. 66, No. 2, August 1991. Printed in U.S.A.
 

Summary:  receivesfunctionally definedcross-orientation inhibition if the cell receivesinhibitory input that is strongest... -orientationinhibition if the inhibition arisesfrom sourcecellswith anorientation preference orthogonalto that of thetargetcell... ,structurallydefinedcross-orientationinhibi- tion resultsin unequalamountsof ...

  

Source: Koch, Christof - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
87 Evidence that descending serotonergic systems protect spinal cord plasticity against the disruptive effect of uncontrollable stimulation
 

Summary:  a protective effect. The a-2 noradrenergic agonist clonidine appeared to protect spinal cord neurons... the adverse effect of uncontrollable stimulation (Experiment 3). The a-2 noradrenergic agonist, clonidine... A examined the impact of the ...

  

Source: Grau, James - Department of Psychology, Texas A&M University

 

Collection: Biology and Medicine

 
88 Limnol. Oceanogr., 47(1), 2002, 8694 2002, by the American Society of Limnology and Oceanography, Inc.
 

Summary:  a first-order exponential equation to the time series: a1 a2exp( rinht) for inhibition and a1 a2exp( rrect... ) for recovery where a1 is the asymptotically ap- proached equilibrium quantum yield, a2 is the change in quantum... ...

  

Source: Michigan State University, Department of Plant Biology, Klausmeier-Litchman Lab.

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
89 Optimization of Amide-Based Inhibitors of Soluble Epoxide Hydrolase with Improved Water Solubility
 

Summary:  . Supporting Information Available: Syntheses and de- tailed analytical data for compounds 3, a-2, a-3, b-2, b... hydrolase inhibition protects the kidney from hypertension-induced damage. J. Am. Soc. Nephrol. 2004, 15... of structural modification of the urea pharmacophore on the ...

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
90 Abstract -This tutorial paper explores the mechanics of protecting computer-stored information from unauthorized
 

Summary:  Abstract - This tutorial paper explores the mechanics of protecting computer-stored information... --whether hardware or software--that are necessary to support information protection. The paper develops in three... protection and authentication mechanisms. Any reader familiar with computers should find the first section

  

Source: Perrig, Adrian - Department of Electrical and Computer Engineering, Carnegie Mellon University

 

Collection: Computer Technologies and Information Sciences

 
91 New Insights into the tPA-Annexin A2 Interaction IS ANNEXIN A2 CYS8
 

Summary:  between tPA and annexin A2. Cysteine-containing peptides also inhibit tPA binding to the surface... for the inhibition, peptides were directly added to rAnxA2, plates were washed, and btn tPA was then added... with the peptides (data not shown). Homocysteine ...

  

Source: Pompeu Fabra, Universitat - Departament de Ciències Experimentals i de la Salut, Proteomics and Protein Chemistry Unit

 

Collection: Biotechnology

 
92 Z .Brain Research 817 1999 151162 Research report
 

Summary:  with halothane 4% halo- .thaner96% O via inhalation and positioned in a2 Narashige small animal stereotaxic... of striatal NADPH diaphorase and enkephalinergic neurons by inhibition of nitric oxide synthase Bettina E... inhibited striatal NOS activity by 85%, while 7-NI 50 mgrkg, i.p. maximally ...

  

Source: Beninger, Richard J. - Department of Psychology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
93 [CANCER RESEARCH 64, 90709075, December 15, 2004] Insulin Regulates Cleavage of Procaspase-9 via Binding of X Chromosome-Linked
 

Summary:  in response to dexamethasone and etoposide (44), and a mitochondrial serine protease, Omi/HtrA2, was suggested... mol/L Akt inhibitor I; A2, 20 mol/L Akt inhibitor II; A3, 20 mol/L Akt inhibitor III. B. Caspase-9... /L rapamycin; A2, 20 mol/L Akt inhibitor II. 9074 ...

  

Source: Massachusetts Institute of Technology (MIT), Cell Decision Process Center

 

Collection: Biology and Medicine

 
94 A Role for G1/S Cyclin-dependent Protein Kinases in the Apoptotic Response to Ionizing Radiation*
 

Summary:  in response of the em- bryo to ionizing radiation. Whereas inhibition of cyclin D1-Cdk4 and cyclin A2-Cdk2... work suggested that inhibition of both cyclin A2-Cdk2 and cyclin D1-Cdk4 by p27Xic1 contributes to G1... of this result is that p27Xic1 does not ...

  

Source: Finkielstein, Carla - Department of Biological Sciences, Virginia Tech

 

Collection: Biology and Medicine

 
95 Short communication The sea urchin embryo as a model for studying
 

Summary:  for studying efflux transporters and estimating energy cost for the cytotoxin protective system provided... after fertilization. Activity results from p-glycoprotein (p-gp) and MRP type transporters which protect... . We find protective roles in protecting the embryo from toxicants and apoptosis and show for ...

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
96 Short Title: Antibodies to MSP-1p19 and protection against malaria Antibodies to the conserved C-terminal domain of the Plasmodium falciparum
 

Summary:  inhibiting P. falciparum erythrocyte invasion in vitro [15]. However, "protection" in this mouse model refers... of antibodies to MSP-1p19 contribute to clinical protection, possibly by inhibiting merozoite invasion... 1 Short Title: Antibodies to MSP-1p19 and protection against malaria ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
97 96:1320-1336, 2006. First published Jun 21, 2006; doi:10.1152/jn.00021.2006J Neurophysiol Zoltan M. Fuzessery, Marlin D. Richardson and Michael S. Coburn
 

Summary:  (see text for formula, predicted 90% inhibition occurs at 1.2 kHz/ms). A: 2-tone inhibition over time... that respond only to downward sweeps. Most neurons (83%) are also tuned to sweep rates. A two-tone inhibition... inhibition that shapes duration tuning, which in ...

  

Source: Fuzessery, Zoltan M. - Department of Zoology and Physiology, University of Wyoming

 

Collection: Biology and Medicine

 
98 Parkinson disease (PD) is a neurodegen-erative disorder characterized by rest-
 

Summary:  to fibrils. -SYN is a natively unfolded protein, but contains an A2 apolipoprotein - helix-like region... that stabilizes a pre- sumably toxic intermediate, the so-called protofibril, by inhibiting its conversion... show an enhanced rate of recovery of DA synaptic transmission4 , whereas inhibition of -SYN ...

  

Source: Sulzer, David - Departments of Neurology & Psychiatry, Columbia University

 

Collection: Biology and Medicine

 
99 Establishment of Survivable Connections in WDM Networks using Partial Path Protection
 

Summary:  ) is the backup path for link x-z on A2. (b) Dedicated partial path protection: A1 is an active path on 1, A2... . illustrates two active paths A1 and A2 and their corresponding (shared) partial path protections. For A1... , a ...

  

Source: Tang, Jian "Neil" - Department of Electrical Engineering and Computer Science, Syracuse University

 

Collection: Computer Technologies and Information Sciences

 
100 Establishment of Survivable Connections in WDM Networks using Partial Path Protection
 

Summary:  ) is the backup path for link x-z on A2. (b) Dedicated partial path protection: A1 is an active path on 1, A2... . illustrates two active paths A1 and A2 and their corresponding (shared) partial path protections. For A1... , a ...

  

Source: Thulsiraman, Krishnaiyan - School of Computer Science, University of Oklahoma

 

Collection: Computer Technologies and Information Sciences


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