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Sample search results for: a7 nicotinic receptor

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1 EDITED B'r' Bertha K. Madras Harvard Medical School
 

Summary:  membrane rich in cholesterol and sphingolipids. For nicotinic receptors, palmitoylation of a7 results... of nicotinic a7 receptors. }. Neurosci. 24: 10502-10510. Ehlers M.D. 2003. Activity level controls postsynaptic... ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
2 Desensitized nicotinic receptors in brain Hai Wanga,*, Xiulan Sunb
 

Summary:  kinetic properties of activation and desensitization on the a7 nicotinic receptors in rat hippocampal... of muscarinic receptors. a7 nAChRs are the most abundant type of nicotinic receptor in the ...

  

Source: Cooper, Robin L. - Department of Biology, University of Kentucky

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
3 This article was published in an Elsevier journal. The attached copy is furnished to the author for non-commercial research and
 

Summary:  .01 methyllycaconitine (MLA, a7 receptors). Ascorbic acid at 1 mM was also added to the extracellular solution to protect... ), AP-5 (NMDA receptors) and methyllycaconitine (MLA, a7 receptors). In previous studies of whole... , Gerzanich V, Anand R, ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
4 JournalofPhysiologyPhysiologyinPress Acetylcholine (ACh) is the major endogenous ligand for
 

Summary:  alpha subunit (a7, a8 or a9) or a combination of a Nicotine is highly effective at producing... for nicotinic receptors, while nicotine is an example of a potent and addictive exogenous ligand... of tobacco products around the world, with associated health problems. ...

  

Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
5 Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus
 

Summary:  MLA, a selective a7 nicotine receptor antagonist (Sharples & Wonnacott, 2001), was used to determine... . Drug Dev. Res., 38, 196­203. Buhler, A.V. & Dunwiddie, T.V. (2002) a7 nicotinic acetylcholine receptors... .V. ...

  

Source: Hasselmo, Michael - Department of Psychology & Computational Neurophysiology Laboratory, Boston University

 

Collection: Biology and Medicine

 
6 Guidelines on nicotine dose selection for in vivo research Shannon G. Matta & David J. Balfour &
 

Summary:  species-specific cytochrome P450 isozymes and nicotinic cholinergic receptors (nAChRs) on neurons. Each... =ml of nicotine hydrogen tartrate needed Nicotine pharmacokinetics, pharmacodynamics, and receptors Components... . Nicotinic cholinergic ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
7 Cellular and Molecular Neurobiology, Vol. 15, No. 4, 1995 Differential Desensitization Properties of Rat
 

Summary:  , functional receptors can be assembled from one type of subunit (e.g., a7), but it is likely that most... oocytes (Boulter et al., 1990). Also, the a7 subunit forms a functional homomeric receptor that presumably... acetylchotine receptor subunit ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
8 ORIGINAL PAPER Cognitive Deficits in Schizophrenia: Focus on Neuronal
 

Summary:  ). Subsequently, studies of neuronal nicotinic receptors in chick sympathetic ganglia (containing a3, a4, a5, a7... of schizophrenia will be discussed. The emphasis will be on two receptor subtypes: the a7-nAChR subtype which... -term exposure to ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
9 ORIGINAL PAPER Contribution of Position a4S336 on Functional Expression
 

Summary:  of neuronal nico- tinic receptors in chick sympathetic ganglia (containing a3, a4, a5, a7, b2, b3, and b4... Neuronal Nicotinic Receptors Gretchen Y. Lo´pez-Herna´ndez Æ Nilza M. Biaggi-Labiosa Æ Alexis Torres... Phosphorylation of the nicotinic acetyl- choline ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
10 ORIGINAL PAPER Contribution of Position a4S336 on Functional Expression
 

Summary:  nico- tinic receptors in chick sympathetic ganglia (containing a3, a4, a5, a7, b2, b3, and b4 subunits... Neuronal Nicotinic Receptors Gretchen Y. Lo´pez-Herna´ndez Æ Nilza M. Biaggi-Labiosa Æ Alexis Torres... - choline receptor (nAChR) is believed to play a ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
11 Nicotine Activation of a4* Receptors: Sufficient for Reward,
 

Summary:  receptors, switches the valence of nicotine from reward to aversion, suggesting a7 receptors can modulate... form hetero- meric channels, whereas a subset, a7 to a10, may form homomeric channels. Nicotine, like... ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
12 Neuron 51, 587600, September 7, 2006 2006 Elsevier Inc. DOI 10.1016/j.neuron.2006.07.025 The Prototoxin lynx1 Acts on Nicotinic
 

Summary:  studies have shown that a7 and a4/b2* nAChRs contribute to the neuroprotective effects of nicotine... .07.025 The Prototoxin lynx1 Acts on Nicotinic Acetylcholine Receptors to Balance Neuronal Activity and Survival In Vivo... Nicotinic acetylcholine ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
13 Psychopharmacology (2003) 165:346358 DOI 10.1007/s00213-002-1260-6
 

Summary:  for upregula- tion of a7 receptors following chronic administration of nicotine (Marks et al. 1985), although... the current understanding is that higher doses of nicotine are needed to upregulate a7 subunit-containing n... of nAChR ...

  

Source: Bruno, John P. - Department of Psychology, Ohio State University

 

Collection: Biology and Medicine

 
14 Nicotine binding to brain receptors requires a strong cationp interaction
 

Summary:  responsible for the fact that a4b2 receptors show consis- tently higher affinity than the homopentameric a7... ). In the lower affinity a7 neuronal receptor, residue 153 is a Gly, and molecular dynamics simulations of a7... ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
15 Cys-loop receptors: new twists and turns
 

Summary:  -neurotoxin-binding sequence on the a7 subunit of a neuronal nicotinic acetylcholine receptor. J. Biol. Chem. 277, 12406... element in the gating of a7 nicotinic receptor. Soc. Neurosci. Abstr. 21, 343 58 England, P.M. et al... ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
16 Second-by-Second Analysis of Alpha 7 Nicotine Receptor Regulation of Glutamate
 

Summary:  of a robust increase in nicotine-induced glutamate, we assessed the contribu- tions of the a7nACh receptor... animals receiving intra- cortical infusions of nicotine separated by infusion of saline or a7nACh receptor... not ...

  

Source: Bruno, John P. - Department of Psychology, Ohio State University

 

Collection: Biology and Medicine

 
17 Assembly and trafficking of nicotinic acetylcholine receptors NEIL S. MILLAR & PATRICIA C. HARKNESS
 

Summary:  , Bertrand D. 1996. Neuronal nicotinic a7 receptor expressed in Xenopus oocytes presents five putative... -bungarotoxin receptors are a7 subunit homomers. J Neurosci 20:133Á 139. [48] Boulter J, Connolly J, Deneris E, Goldman D... Assembly and ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
18 Nicotine use in schizophrenia: The self medication hypotheses Veena Kumaria,
 

Summary:  an interaction between the low affinity (i.e. a7 subunit containing) nicotinic receptors and glutamatergic... linked to the a7-nicotinic cholinergic receptor subunit gene locus (Freedman et al., 1997, 2001... -induced ...

  

Source: Cooper, Robin L. - Department of Biology, University of Kentucky

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
19 The Neurobiology of Information Storage Training Program Fifth Annual Lecture on Neuroclinical Approaches to Mood and Mentation
 

Summary:  acetylcholine receptors (nAChRs) and the neurobiology of nicotine addiction. The approach has been to use... rescue of these receptors to identify the anatomical basis for behaviors related to nicotine addiction... related to nicotine addiction, the role of nicotinic ...

  

Source: Northwestern University, Dynamics of Complex Systems in Science and Engineering Center

 

Collection: Engineering

 
20 The Journal of Neuroscience, May 1995, 15(5): 3679-3687 Arachidonic Acid as a Possible Negative Feedback Inhibitor of
 

Summary:  to have the highest permeability to cal- cium, namely receptors containing a7 subunits. Low con... - centrations of arachidonic acid also reversibly inhibit a7- containing receptors expressed in Xenopus oocytes... -electrode voltage- clamp recording techniques were ...

  

Source: Betz, William J. - Department of Physiology and Biophysics, University of Colorado Health Sciences Center

 

Collection: Biology and Medicine


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21 Thse de Doctorat de l'Universit PIERRE ET MARIE CURIE
 

Summary:  > cytisine ; pour les récepteurs a44 : cytisine > nicotine > ACh; pour les homorécepteurs a7 : nicotine... ) Cannabinoid CB1 receptors are involved in motivational effects of nicotine in rats. Psychopharmacology (Berl... qui peuvent être ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
22 Long-Term Nicotine Adaptation in Caenorhabditis elegans Involves PKC-Dependent Changes in Nicotinic Receptor Abundance
 

Summary:  to nicotine leads to long-term changes in both the abundance and activity of nicotinic acetylcholine receptors... , prolonged nicotine treat- ment results in a long-lasting decrease in the abundance of nicotinic receptors... -laying by the ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
23 ORIGINAL PAPER Daniel G. Wu stenberg Bernd Gru newald
 

Summary:  containing the a7-subunit and the honeybee nicotinic current (Goldberg et al. 1999). In both cases, a high Ca... Eyseren et al. 1998). In ver- tebrates, MLA specifically blocks a7 containing neuro- nal receptors... similarity between the insect ...

  

Source: Menzel, Randolf - Institut für Biologie - Institut für Biologie, Freie Universität Berlin

 

Collection: Biology and Medicine

 
24 Nicotine responses in hypersensitive and knockout 4 mice account for tolerance to both hypothermia and locomotor suppression in wild-type mice
 

Summary:  ; nicotinic receptors; locomotion NEURONAL nAChRs are cation-selective ligand-gated ion chan- nels... -in" Leu9 Ala mouse line allows for the selective activation of 4* receptors with small doses of nicotine... and equals unity for nicotine doses too low to activate non- 4 ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
25 Mini-Review Theme: NIDA Symposium: Drugs of Abuse: Cutting-edge Research Technologies
 

Summary:  " of nicotinic receptors (nAChRs). If the hypothesis is proven, (1) SePhaChARNS is the molecular mechanism... important implication of the SePhaChARNS hypothesis is that therapeutically relevant nicotinic receptor... example is in the midbrain. Chronic nicotine exposure cell-selectively ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
26 ORIGINAL ARTICLE Altered activityrest patterns in mice with a human
 

Summary:  frontal lobe epilepsy mutation in the b2 nicotinic receptor J Xu1,2 , BN Cohen3 , Y Zhu1,2 , G... of Technology, Pasadena, CA, USA High-affinity nicotinic receptors containing b2 subunits (b2*) are widely... phenotype to that found in human ADNFLE patients. Consistent with the role of ...

  

Source: Contractor, Anis - Department of Physiology, Northwestern University

 

Collection: Biology and Medicine

 
27 Counting Bungarotoxin Binding Sites of Nicotinic Acetylcholine Receptors in Mammalian Cells with High Signal/Noise Ratios
 

Summary:  nicotinic a7 receptor expressed in Xenopus oocytes presents five putative binding sites... promotes func- tional expression of the nicotinic acetylcholine receptor a7 subunit in mammalian cells. J... molecule approaches. Here ...

  

Source: Selvin, Paul R. - Department of Physics, University of Illinois at Urbana-Champaign

 

Collection: Physics ; Materials Science

 
28 Case Study 1: Determining Key Binding Interactions Between the Neurotransmitter
 

Summary:  Acetylcholine Receptor (nAChR) Acetylcholine (ACh) O N+ CH3 CH3 CH3 O Nicotine N+ N CH3 H The natural ligand... Recognition at Serotonergic (5-HT3A) and Nicotinic Acetylcholine Receptors. The Anomalous Binding Properties... at the Nicotinic Acetylcholine Receptor, ...

  

Source: Stoltz, Brian M. - Division of Chemistry and Chemical Engineering, California Institute of Technology

 

Collection: Chemistry

 
29 Potentiation of evoked calcitonin gene-related peptide release from oral mucosa: a potential basis for the
 

Summary:  ; Southall et al., 2003) and are known to express several nicotinic receptor subunits including a3, a5, a7, b... ) as well as a-bungarotoxin- binding sites, probably a7 receptors (Schechter et al., 1978). Func- tional ...

  

Source: Price, Theodore - Department of Pharmacology, University of Arizona

 

Collection: Biology and Medicine

 
30 Identification and characterization of novel nicotinic receptor-associated proteins
 

Summary:  Identification and characterization of novel nicotinic receptor-associated proteins... receptor; SOC-1; tandem affinity purification; TAX-6 calcineurin Introduction Nicotinic acetylcholine... in lane 4. Bands of 30 and 28 kDa correspond to TEV-protease. Nicotinic ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
31 Copyright 2004 by the Genetics Society of America eat-2 and eat-18 Are Required for Nicotinic Neurotransmission in the
 

Summary:  eat-2 encodes a nicotinic receptor subunit: eat-2 mapssequence is from Y105E8A.7 and the lowercase... 8A.7 genomic se- for genes that were likely to be involved in nicotinic quence and ends... to pump rapidly in the presence of food. EAT-2 is a ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
32 Genetic Analysis of Nicotinic Signaling in Worms William R. Schafer
 

Summary:  2002 ABSTRACT: The nicotinic acetylcholine receptor is among the most thoroughly characterized... , and the pros- pects for using these studies to gain insight into nicotinic receptor function and regulation... acetylcholine receptor NICOTINIC SIGNALING IN ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
33 Brain Research 959 (2003) 98102 www.elsevier.com/locate/brainres
 

Summary:  with similar affinity to nicotinic a4b2 receptors on the cell surface and in homogenates *Jessie Zhang, Joe... , and receptors Topic: Acetylcholine receptors: nicotinic Keywords: Nicotine; Agonist affinity; Cell surface 1... . Introduction ...

  

Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
34 Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action
 

Summary:  633 Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action Henry... nicotinic acetylcholine receptors containing 4 - or 7 -subunits. The full expression of the stronger alleles... acetylcholine receptors, smoking cessation Abbreviations ACh Acetylcholine ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
35 In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity
 

Summary:  AChR activation is independent of AMPA receptor function, action potentials, and a7* nAChRs. The indicated drug... * Nicotinic Acetylcholine Receptors Ryan M. Drenan,1 Sharon R. Grady,2 Paul Whiteaker,2,6 Tristan Mc... 6*) nicotinic ACh receptors ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
36 a-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses
 

Summary:  receptors and PnIB is selective for a7-containing receptors (rat subunits expressed in Xenopus oocytes [56... selective for a7-containing receptors, more so than PnIB itself, and that [Asn11Ser]PnIA had reduced... 10Leu]PnIA block different ...

  

Source: Janes, Bob - School of Biological and Chemical Sciences, Queen Mary, University of London

 

Collection: Biology and Medicine

 
37 NICOTINE CONTROL OF DOPAMINE SIGNALING IN THE VENTRAL TEGMENTAL AREA
 

Summary:  ). This increase results from direct stimulation of nicotinic acetylcholine receptors (nAChRs) expressed in the VTA... knockout mice suggest that the key are 2 nAChRs on DA neurons [27]. These receptors furnish nicotinic... strength of the respective connection. Cholinergic input activates ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
38 Presynaptic Nicotinic Receptors Facilitate Monoaminergic Transmission
 

Summary:  Presynaptic Nicotinic Receptors Facilitate Monoaminergic Transmission Xiangyang Li, Donald G... a nicotinic receptor-mediated presynaptic enhancement of fast glutamatergic (McGehee et al., 1995; Gray et al... of presynaptic nicotinic receptors induced a depolarization ...

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
39 Acta Pharmacol Sin 2009 Jun; 30 (6): 681693 Acta Pharmacologica Sinica 2009 CPS and SIMM
 

Summary:  tegmental area (VTA) are combined with explicit models of the dynamics of specific nicotinic ACh receptor... effects on nicotinic acetylcholine receptors with neurodynamics of local circuitry and show its potential... receptors, the nicotine would boost the expected ...

  

Source: Gutkin, Boris - Group for Neural Theory, Collège de France

 

Collection: Computer Technologies and Information Sciences

 
40 NICOTINIC RECEPTOR-MEDIATED RESPONSES IN RELAY CELLS AND INTERNEURONS IN THE RAT LATERAL
 

Summary:  NICOTINIC RECEPTOR-MEDIATED RESPONSES IN RELAY CELLS AND INTERNEURONS IN THE RAT LATERAL GENICULATE... synaptic transmission. This suggests that the depolarization is mediated directly by nicotinic receptors... to calcium ions. Our results indicate that nicotinic ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine


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41 Naturally Occurring Variants of Human A9 Nicotinic Receptor Differentially Affect Bronchial Cell Proliferation
 

Summary:  , Grando SA (1997) Nicotine enhances expression of the a3, a4, a5, and a7 nicotinic receptors modulating... Naturally Occurring Variants of Human A9 Nicotinic Receptor Differentially Affect Bronchial Cell... of multiple isoforms of RNA coded by the ...

  

Source: Loudon, Catherine - Department of Ecology and Evolutionary Biology, University of California, Irvine

 

Collection: Environmental Sciences and Ecology

 
42 Characterization of Determinants of Ligand Binding to the Nicotinic Acid Receptor GPR109A (HM74A/PUMA-G)
 

Summary:  Characterization of Determinants of Ligand Binding to the Nicotinic Acid Receptor GPR109A (HM74A... -protein-coupled receptor GPR109A (HM74A/PUMA-G) has recently been shown to function as a receptor for nicotinic acid... -protein-coupled receptor that binds ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
43 The Neurobiology of Information Storage Training Program (NISTP)
 

Summary:  to, activates and desensitizes nicotinic acetylcholine receptors (nAChRs), but it is not known... -smokers often experiencing increased depressive symptoms immediately after quitting. Nicotine in tobacco binds... whether activation or desensitization is more important for nicotine's effects on depressive ...

  

Source: Northwestern University, Dynamics of Complex Systems in Science and Engineering Center

 

Collection: Engineering

 
44 The Neurobiology of Information Storage Training Program (NISTP) Fifth Annual Lecture
 

Summary:  to, activates and desensitizes nicotinic acetylcholine receptors (nAChRs), but it is not known... -smokers often experiencing increased depressive symptoms immediately after quitting. Nicotine in tobacco binds... whether activation or desensitization is more important for nicotine's effects on depressive ...

  

Source: Contractor, Anis - Department of Physiology, Northwestern University

 

Collection: Biology and Medicine

 
45 Genetic Approaches Identify Differential Roles for 4 2* Nicotinic Receptors in Acute Models of Antinociception in Mice
 

Summary:  Genetic Approaches Identify Differential Roles for 4 2* Nicotinic Receptors in Acute Models... The effects of nicotine on the tail-flick and hot-plate tests were determined to identify nicotinic receptor... hypersensitive 4 nicotinic receptors (L9 ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
46 Functional Contribution of a3L80 Neuronal Nicotinic a3 Receptor
 

Summary:  that form a functional homomeric receptor (e.g., a7). To date, 12 neuronal nAChR subunits have been... in determin- ing the role of the predominant receptor subtypes in the brain (a4b2 and a7 receptors) during... Functional Contribution of a3L80 ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
47 Corticotropin-Releasing Factor-1 Receptor Activation Mediates Nicotine Withdrawal-Induced Deficit in Brain
 

Summary:  Corticotropin-Releasing Factor-1 Receptor Activation Mediates Nicotine Withdrawal-Induced Deficit... of CRF1 and CRF2 receptors in the deficit in brain reward function associated with precipitated nicotine... , the nicotinic receptor antagonist mecamylamine elevated ...

  

Source: Príncipe, José Carlos - Computational NeuroEngineering Laboratory, University of Florida

 

Collection: Engineering ; Computer Technologies and Information Sciences

 
48 Nicotinic Receptor-Induced Apoptotic Cell Death of Hippocampal Progenitor Cells
 

Summary:  Nicotinic Receptor-Induced Apoptotic Cell Death of Hippocampal Progenitor Cells Francois Berger,1... on neuronal nicotinic acetylcholine receptors (AChRs). One subclass of AChRs that binds the snake venom toxin... for -Bgt-AChRs in neuronal development and differentiation. Key words: ...

  

Source: Betz, William J. - Department of Physiology and Biophysics, University of Colorado Health Sciences Center

 

Collection: Biology and Medicine

 
49 15E N G I N E E R I N G & S C I E N C E N O . 42 0 0 2 16 E N G I N E E R I N G & S C I E N C E N O . 4 2 0 0 2
 

Summary:  a proton--in order to act on each drug's specific receptor in the brain. If the nicotine molecule gained... on a neurotransmitter- activated receptor bearing the full name of nicotinic acetylcholine receptor (because acetyl... . The receptor straddles the cell ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
50 Characterizing Ligand-Gated Ion Channel Receptors with Genetically Encoded Ca++
 

Summary:  . In particular, we describe separate lines with human a7 and human a4b2 nicotinic acetylcholine receptors, mouse... of the HEKtsA201 human a7-Ric3 nicotinic receptor stable cell lines and their pharmacological properties ...

  

Source: Kleinfeld, David - Computational Neuroscience Group, Department of Physics, University of California at San Diego

 

Collection: Biology and Medicine

 
51 Behavioral/Systems/Cognitive Chronic Nicotine Cell Specifically Upregulates Functional
 

Summary:  ,arealteredbycontinuedexposuretothedrug.Toaddressthisproblem,wedevelopedmicewhose 4nicotinic receptor subunits are replaced by normally functioning fluorescently tagged subunits... system dominates reward pathways, chronic nicotine does not change 4* receptor levels in dopaminergic... addiction; GFP; knock-in ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
52 Distinct subcellular targeting of uorescent nicotinic a3b4 and serotoninergic 5-HT3A receptors in
 

Summary:  ) Some properties of the human neuronal a7 nicotinic acetylcholine recep- tors fused to the green... Distinct subcellular targeting of ¯uorescent nicotinic a3b4 and serotoninergic 5-HT3A receptors... , receptors, serotoninergic, targeting Abstract The ...

  

Source: Cossart, Rosa - Institut de Neurobiologie de la Méditerranée, Inserm

 

Collection: Biology and Medicine

 
53 BRIEF REPORT Transdermal nicotine has positive effects on behavioral disturbances related to Au-
 

Summary:  and acetyltransferase. Nicotine stimulates high affinity receptor proliferation7, 8 and has also been shown... suggestion4 that "therapeutic strategies [for autism] could include receptor agonists, such as nicotine." 2... at nicotinic receptors.10 Still, potentiation ...

  

Source: Schaffer, William M. - Department of Ecology and Evolutionary Biology, University of Arizona

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
54 Nicotine-induced Up-regulation and Desensitization of 4 2 Neuronal Nicotinic Receptors Depend on Subunit Ratio*
 

Summary:  Nicotine-induced Up-regulation and Desensitization of 4 2 Neuronal Nicotinic Receptors Depend... receptor (nAChR) in the central nervous system. We studied the effect of acute and chronic nicotine... that independent structural sites regulate 4 2 receptor activation ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
55 Journal of Molecular Neuroscience 181 Volume 30, 2006 *Author to whom all correspondence and reprint requests should be addressed. E-mail: raad@caltech.edu
 

Summary:  , CA 91125 Introduction Nicotinic acetylcholine receptors (nAChRs) are members of the Cys... ),whichmake sparse projections to a wide distribution of high- affinity nicotinic receptors in the brain... . Subcellular Neuronal nAChR Localization Although most nicotinic ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
56 A neurocomputational hypothesis for nicotine addiction
 

Summary:  to nicotine addiction. We propose that combin- ing changes in the nicotinic receptor response, expressed... -selection; DA, dopaminergic; nAChR, nicotinic acetylcholine receptor; VTA, ventral tegmental area. §To whom... . Changeux, J.-P. & Edelstein, S. E. (2005) ...

  

Source: Gutkin, Boris - Group for Neural Theory, Collège de France

 

Collection: Computer Technologies and Information Sciences

 
57 Neurobiology of Disease Novel Seizure Phenotype and Sleep Disruptions in Knock-In
 

Summary:  with Hypersensitive 4* Nicotinic Receptors Carlos Fonck,1 Bruce N. Cohen,1 Raad Nashmi,1 Paul Whiteaker,3 Daniel A... receptors in mice mediate changes in the sleep­wake cycle and nicotine- induced seizures resembling ADNFLE... . Key words: epilepsy; ADNFLE; nicotinic ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
58 Critical Review Recent Advances in Understanding the Structure of Nicotinic
 

Summary:  ) of the cytoplasmic loop of a7 nAChR has been shown to affect the expression of this subtype receptor (76). Apparently... Critical Review Recent Advances in Understanding the Structure of Nicotinic Acetylcholine Receptors... of Patras, Patras, Greece Summary Nicotinic ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
59 in Burger's Medicinal Chemistry, Vol II Drug Discovery and Drug Development, Chapter 11, pp 357-405. Ed. Abraham, D.,
 

Summary:  11, pp 357-405. Ed. Abraham, D., J. Wiley, New York., Nicotinic acetylcholine receptors David... .colquhoun@ucl.ac.uk) - #12;2 ABSTRACT Nicotinic receptors are cation-permeable ion channels activated by the neurotransmitter... for muscle and epilepsy for neuronal receptors). #12;3 ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
60 task performance is observed (Kumari et al 2003; Lawrence et al In this study, we used fMRI to test the hypothesis that
 

Summary:  , the thalamus has among the highest concentrations of high-affinity nicotinic acetylcholine receptors (n... group differences in severity of nicotine dependence. Nicotinic receptors desensitize following exposure... AChR receptor function or response to ...

  

Source: Yale University, Haskins Laboratories

 

Collection: Multidisciplinary Databases and Resources ; Biology and Medicine


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61 Nicotinic Receptors Mediate Changes in Spinal Motoneuron Development and Axonal Pathfinding in Embryonic Zebrafish
 

Summary:  Nicotinic Receptors Mediate Changes in Spinal Motoneuron Development and Axonal Pathfinding... that is not ameliorated by drug withdrawal. These effects of nicotine were reversed by mammalian nicotinic receptor... . In experiments in which nicotinic ...

  

Source: Tullos, Desiree - Department of Biological and Ecological Engineering, Oregon State University

 

Collection: Environmental Sciences and Ecology

 
62 PHS 398/2590 (Rev 05/01) Page Biographical Sketch Format Page Principal Investigator/Program Director (Last, First, Middle): Gerzanich, Vladimir
 

Summary:  of the nicotinic acetylcholine receptor. Biochemistry, 32:9975-9984. Peng, X., Katz, M., Gerzanich, V., Anand, R... of _ 8 subunits of nicotinic receptors functionally expressed in Xenopus oocytes exhibit similar channel... ., Anand, R., Whiting, P., Lindstrom, J. (1994) Nicotine-induced ...

  

Source: Weber, David J. - Department of Biochemistry and Molecular Biology, University of Maryland-Baltimore

 

Collection: Biology and Medicine

 
63 ORIGINAL PAPER Study of nicotinic acetylcholine receptors on cultured antennal
 

Summary:  K, Sattelle DB (2000) Role of loop D of the a7 nicotinic acetylcholine receptor in its interaction... ORIGINAL PAPER Study of nicotinic acetylcholine receptors on cultured antennal lobe neurones from... functions. Keywords Nicotinic acetylcholine ...

  

Source: Menzel, Randolf - Institut für Biologie - Institut für Biologie, Freie Universität Berlin

 

Collection: Biology and Medicine

 
64 Alteration in Ion Channel Function of Mouse Nicotinic Acetylcholine Receptor by Mutations in the M4 Transmembrane Domain
 

Summary:  Alteration in Ion Channel Function of Mouse Nicotinic Acetylcholine Receptor by Mutations in the M4... -- Ion channel gating Introduction The nicotinic acetylcholine receptor is a member of li- gand-gated ion... in other AChR. 159S. Tamamizu et al.: Effects of M4 Mutations on the Mouse ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
65 SPECIAL ISSUE Gene expression is differentially regulated by neurotransmitters in embryonic neuronal cortical
 

Summary:  and neurodevelopmental dis- orders. The role that nicotinic receptors play in immature cortical neurons was initially... for adult brain repair and/or neuroprotection. Nicotinic acetylcholine receptors (nAChRs) are ligand- gated... of nicotinic receptors are not ...

  

Source: Smith, Desmond J. - Department of Molecular and Medical Pharmacology, University of California at Los Angeles

 

Collection: Biology and Medicine

 
66 Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the a6* subtype
 

Summary:  * (the asterisk denotes the presence of additional subunits and/or stoichi- ometries) and a7 receptors... b2* activity, varenicline also interacts with a7 and a6b2* receptors.8 Compounding this complexity... Evaluation of structurally diverse neuronal ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
67 ORIGINAL PAPER Guillaume Stephane Barbara Christina Zube
 

Summary:  -induced cur- rent flows through a cation-selective ionotropic receptor with a nicotinic profile. The ACh... brain and insect neurons express several different neuronal nicotinic receptors (Lapied et al. 1990... . Functional ionotropic GABA, nicotinic, and glutamate ...

  

Source: Menzel, Randolf - Institut für Biologie - Institut für Biologie, Freie Universität Berlin

 

Collection: Biology and Medicine

 
68 2009 The Authors Journal compilation 2009 The Royal Entomological Society 233
 

Summary:  al. (2003) Identification of an alternatively processed nicotinic receptor a7 subunit RNA in mouse... in nicotinic acetylcholine receptor subunits of the red flour beetle, Tribolium castaneum F. D. Rinkevich and J... Sequence analysis of 168 cDNA clones encoding 12 ...

  

Source: Scott, Jeffrey G. - Department of Entomology, Cornell University

 

Collection: Environmental Sciences and Ecology

 
69 Neurobiology of Disease Chronic Nicotine Selectively Enhances 4 2* Nicotinic
 

Summary:  nicotinic acetylcholine receptor (nAChR) subunit knock-out mice. Chronic nicotine enhanced... , 2005). The longest-known effect of chronic nicotine is upregulation of nicotinic receptors themselves... A, n 4; p 0.001) (data not shown). This apparent ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
70 Increased Sensitivity to Agonist-Induced Seizures, Straub Tail, and Hippocampal Theta Rhythm in Knock-In Mice
 

Summary:  in Knock-In Mice Carrying Hypersensitive 4 Nicotinic Receptors Carlos Fonck,1 Raad Nashmi,1 Purnima... studied a strain of exon replacement mice ("L9 S knock-in") whose 4 nicotinic receptor subunits have... -containing receptors hypersensitive to agonists. Nicotine ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
71 Behavioral/Systems/Cognitive 4* Nicotinic Receptors in preBotzinger Complex Mediate
 

Summary:  Behavioral/Systems/Cognitive 4* Nicotinic Receptors in preBo¨tzinger Complex Mediate Cholinergic/Nicotinic... respiratory patterns by acting on nicotinic acetylcholine receptors (nAChRs) in the preBo¨tz- inger complex... muscarinic acetylcholine receptors (AChRs) ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
72 Nicotinic Partial Agonists Varenicline and Sazetidine-A Have Differential Effects on Affective Behavior
 

Summary:  and preclinical studies suggest that nicotinic acetylcho- line receptors are involved in affective disorders... , have been shown to act as noncompetitive nicotinic receptor (nAChR) antagonists on the cellular... in prolonged periods of receptor desensitiza- tion (Hulihan-Giblin et al., ...

  

Source: Shorter, James - Department of Biochemistry and Biophysics, University of Pennsylvania

 

Collection: Biology and Medicine

 
73 Cellular/Molecular Galantamine Activates Muscle-Type Nicotinic Acetylcholine
 

Summary:  Cellular/Molecular Galantamine Activates Muscle-Type Nicotinic Acetylcholine Receptors without... activate the nicotinic ACh receptor or modulate its activation by ACh. In this study, we have examined... the ability of galantamine to directly activate the muscle-type nicotinic ACh ...

  

Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
74 Knockin mice with Leu9 Ser 4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally
 

Summary:  Knockin mice with Leu9 Ser 4-nicotinic receptors: substantia nigra dopaminergic neurons... nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost... is therefore probably an increased sensitivity to acetylcholine or choline of 4-containing ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
75 Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50
 

Summary:  is likely to represent an a7-like homopentameric receptor (Ballivet et al, 1996; Francis et al, 2005... Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50 Stefan Eimer... , USA Nicotinic acetylcholine receptors ...

  

Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
76 Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50
 

Summary:  of this receptor, which is likely to represent an a7-like homopentameric receptor (Ballivet et al, 1996; Francis et... Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50 Stefan Eimer... , USA Nicotinic ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
77 iving up smoking is easy. I've done it hundreds of times." This quote by
 

Summary:  dem- onstrate that chronic exposure to nicotine can "desensitize" these receptors, making them less... sites might reflect an increased number of receptors that may compensate for nicotine- induced... on the 42 nicotinic acetylcholine receptors of neurons.Activation ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
78 J Physiol 586.21 (2008) p 5277 5277 CORRIGENDUM
 

Summary:  in experiments with nicotinic receptors, we have found that the clone used in this paper did not contain the L78P... that was not quite the same as that of the wild-type human muscle type nicotinic acetyl- choline receptor, epsilon... ) of the muscle nicotinic acetylcholine ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
79 2-[11C]Methyl-5-[6-phenylpyridazine-3-yl]octahydropyrrolo[3,4-c] [ [11C]A-582941]
 

Summary:  : [11 C]A-582941 Synonym: Agent category: Compound Target: Neuronal 7 nicotinic acetylcholine receptor... permeability to ions, such as Na+ and Ca2+ (2-4). Nicotinic receptors exist as pentamers (homomeric... . Albuquerque E.X. The nicotinic acetylcholine receptor ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
80 This article was originally published in a journal published by Elsevier, and the attached copy is provided by Elsevier for the
 

Summary:  . J Neurosci 1999, 19:5693-5702. 45. Alkondon M, Albuquerque EX: Nicotinic acetylcholine receptor a7... , Rogers JA, Kocsis B, Hajos M: Activation of a7 acetylcholine receptors augments stimulation... muscarinic and nicotinic ...

  

Source: Hasselmo, Michael - Department of Psychology & Computational Neurophysiology Laboratory, Boston University

 

Collection: Biology and Medicine


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81 2-(5-[11C]Methyl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-xanthene-9-[ [11C]A-844606]
 

Summary:  C]A-844606 Synonym: Agent category: Compound Target: Neuronal 7 nicotinic acetylcholine receptor (n... information in PubChem. Background [PubMed] Neuronal 42 nicotinic cholinergic receptors (nAChRs) are part... + and Ca2+ (1-3). Nicotinic receptors exist as pentamers ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
82 Fast synaptic transmission in autonomic ganglia is mediated by the release of acetylcholine and the activation
 

Summary:  and the activation of nicotinic receptors. It has been known for a long time that these receptors differ from those... . It is known that nicotinic acetylcholine receptors at the neuromuscular junction are pentamers formed by four... that is known about how they assemble to form the ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
83 P. T. F. Williamson B. H. Meier A. Watts Structural and functional studies of the nicotinic acetylcholine
 

Summary:  of the nicotinic acetylcholine receptor by solid-state NMR Received: 1 September 2003 / Revised: 17 November 2003... of the nicotinic acetylcholine receptor. These studies have provided detailed structural information relating... - ments derived from the nicotinic acetylcholine ...

  

Source: Watts, Anthony - Biomembrane Structure Unit, Department of Biochemistry, University of Oxford

 

Collection: Biology and Medicine

 
84 A Single Dose of Nicotine Enhances Reward Responsiveness in Nonsmokers: Implications for
 

Summary:  appetitive responding for nondrug incentives via activation of presynaptic nicotinic receptors (n... A Single Dose of Nicotine Enhances Reward Responsiveness in Nonsmokers: Implications... Evins Background: Tobacco smoking, driven by the addictive properties of nicotine, is the most prevalent

  

Source: Pizzagalli, Diego - Department of Psychology, Harvard University

 

Collection: Biology and Medicine

 
85 Nicotine-Induced Dopamine Release in Primates Measured C]Raclopride PET
 

Summary:  , 1996). Nicotinic receptors appear to be present on the cell bodies of DA neurons in the ventral... potentials and that this regulatory effect of acetylcholine is mediated by nicotinic receptors (Zhou et al... receptor occupancy changes over a period of a few hours after ...

  

Source: Morris, Evan - Purdue School of Engineering and Technology & Department of Radiology, Indiana University-Purdue University Indianapolis

 

Collection: Engineering ; Biology and Medicine

 
86 Z .Brain Research 788 1998 118124 Research report
 

Summary:  -tubocurarine, a nonselective blocker of nicotinic receptors, and it indicates that mecamylamine preferentially interacts... with nicotinic receptors on sympathetic C neurons. We tested this by analyzing the effect of mecamylamine upon... between nicotinic receptors ...

  

Source: Horn, John P. - Department of Neurobiology, University of Pittsburgh

 

Collection: Biology and Medicine

 
87 Using Physical Chemistry To Differentiate Nicotinic from Cholinergic Agonists at the Nicotinic Acetylcholine Receptor
 

Summary:  ), nicotine, and epibatidinesto the nicotinic acetylcholine receptor has been probed using unnatural amino... the activity of nicotine at the nAChR is that nicotine has low agonist potency at the muscle receptor subtype... it is known as the ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
88 30 Gao et al. Archives of Insect Biochemistry and Physiology January 2007 doi: 10.1002/arch.
 

Summary:  . 1990. A neuronal nicotinic acetylcholine receptor subunit (a7) is developmentally regulated and forms... of the Nicotinic Acetylcholine Receptor Subunit Gene Mda2 From the House Fly, Musca domestica Jian-Rong Gao... , Juliane M. Deacutis, and Jeffrey G. Scott* A ...

  

Source: Scott, Jeffrey G. - Department of Entomology, Cornell University

 

Collection: Environmental Sciences and Ecology

 
89 Serotonin is a biogenic amine that activates a large and heterogeneous family of receptors that are widely
 

Summary:  isolated (Maricq et al. 1991) appears structurally related to the neuronal nicotinic a7 and a8 subunits... that includes the nicotinic acetylcholine, y-aminobutyric acid type A and glycine receptors. Recombinant... , the neuronal nicotinic a4 ...

  

Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
90 JournalofPhysiology Autosomal dominant nocturnal frontal lobe epilepsy
 

Summary:  . 1999) and two b2 nicotinic acetylcholine receptor (nAChR) mutations (DeFusco et al. 2000; Phillips et... Institute of Technology, Pasadena, CA 91125, USA Five nicotinic acetylcholine receptor (nAChR) mutations... receptor activation. Since the a4:b2 subunit stoichiometry is expected to ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
91 4-[5-(4-[18F]Fluoro-phenyl)-[1,3,4]oxadiazol-2-yl]-1,4-diaza-bicyclo [3.2.2]nonane
 

Summary:  information in PubChem. Background [PubMed] Neuronal 42 nicotinic cholinergic receptors (nAChRs) are part... permeability to ions such as Na+ and Ca2+ (1-3). Nicotinic receptors exist as pentamers (homomeric... . Albuquerque E.X. The nicotinic acetylcholine receptor ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
92 Supplementary Fig. 1: Expression patterns of translational fusions of ACR-8, ACR-12 and ACR-13 to GFP
 

Summary:  ). Supplementary material for Gottschalk et al.: Nicotinic receptor functional proteomics 1 #12;C: A truncated ACR... for Gottschalk et al.: Nicotinic receptor functional proteomics 2 #12;Supplementary Figure 2: Antibodies injected... material for Gottschalk et al.: Nicotinic ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
93 Drug use as potential protection against pathogens: Tobacco consumption vs. helminth load in
 

Summary:  Acetylcholine (neurotransmitter) Acetylcholine receptors at neuromuscular junction Nicotine (plant neurotoxin... toxins, many that severely disrupt neuronal signaling #12;Nicotine Lots of research on this commercially... important, socially burdensome cholinergic neurotoxin Nicotiana attenuata #12;Defensive action of ...

  

Source: 

 

Collection: Biology and Medicine

 
94 Contribution of Valine 70 Gating of Neuronal a3 Receptor Subtypes
 

Summary:  nico- tinic a3 receptors. VVC 2006 Wiley-Liss, Inc. Key words: AChR; nicotine; acetylcholine... ) of the channel after prolonged exposure to the agonist. Nicotinic acetylcholine receptors (nAChRs) are members... receptors showed a decline in peak current at high ...

  

Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras

 

Collection: Biology and Medicine

 
95 NEUROSCIENCE Perceptions of
 

Summary:  , at times, idiosyncratic) read. The nicotinic acetylcholine receptors are often referred to as the most... in vertebrates, but the sorts of nicotinic receptor that occur in the central... of the ion channel within it. This book covers everything about the nicotinic ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
96 Cellular/Molecular Assembly of 4 2 Nicotinic Acetylcholine Receptors
 

Summary:  Cellular/Molecular Assembly of 4 2 Nicotinic Acetylcholine Receptors Assessed with Functional... .Transfectedmidbrainneuronsthatwereexposedtonicotine(1d)displayedgreaterlevelsoffluorescent 4and 2nicotinicACh receptor (nAChR) subunits. As expected... receptors; receptor ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
97 JournalofPhysiology The discovery of the genetic basis for many of the human
 

Summary:  in investigation of the relationship between structure and function in the nicotinic acetylcholine receptor (ACh... on the conformation change Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic... activation of nicotinic receptors ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
98 human psychopharmacology Hum Psychopharmacol Clin Exp 2004; 19: 409419.
 

Summary:  desensitization. Nicotinic receptors (in particular the alpha-7) are known to desensitize rapidly when activated... by a ligand. Therefore, presumably, central activation of nicotinic receptors is best produced by fast rising... 2004 in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/hup.604 ...

  

Source: Sereno, Anne B. - Department of Neurobiology and Anatomy, University of Texas Health Science Center Houston

 

Collection: Biology and Medicine

 
99 Bren Professor of Biology: Henry A. Lester George Grant Hoag Professor of Chemistry: Dennis
 

Summary:  4 receptor and the serotonin 5-HT3 receptor. The nicotinic receptor work is enhanced by a promising... , neurodegenerative disease, and epilepsy. Strains that contain GFP tags on their nicotinic receptors... role of the 7 nicotinic ...

  

Source: Elowitz, Michael - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
100 Differential Effects of Nicotine and Complex Housing on Subsequent Experience-Dependent Structural Plasticity in the Nucleus Accumbens
 

Summary:  ). Although it is tempting to link these impairments to nicotinic receptor upregulation associated... Differential Effects of Nicotine and Complex Housing on Subsequent Experience-Dependent Structural... whether prior experience blocks subsequent nicotine-related structural plasticity. Rats were given daily

  

Source: Hamilton, Derek - Department of Psychology, University of New Mexico

 

Collection: Biology and Medicine


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