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Sample search results for: a2a receptor complex

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1 J Neural Transm (2007) 114: 4975 DOI 10.1007/s00702-006-0589-0
 

Summary:  further strengthened by the discovery of a mGluR5=A2A heteromeric receptor complex (Ferre´ et al., 2002... for treatment of Parkinson's disease (A2A and mGluR5 receptor antagonists), schizophrenia ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
2 This article was originally published in the Encyclopedia of Neuroscience published by Elsevier, and the attached copy is provided by Elsevier for the
 

Summary:  Four different P1 receptor subtypes, A1, A2A, A2B, and A3, have been cloned. All are G... -protein-coupled receptors (GPCRs). At 318 amino acids in length, the A3 subtype is the shortest, while A2A is the longest... - ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
3 P2 receptor web: Complexity and fine-tuning Cinzia Volont a,, Susanna Amadio a
 

Summary:  P2 receptor web: Complexity and fine-tuning Cinzia Volonté a,, Susanna Amadio a , Nadia D... and molecular complexity among P2 receptors and to integrate and upgrade their assortment is to regard them... molecular complexity of P2 receptors is further demonstrated by ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
4 JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION Vol. 24, No. 3, pp. 165205, 2004
 

Summary:  receptor stimulation induces a complex modulation of Ca2þ potentials in prefrontal cortex neurons. D1-like... may enhance NMDA receptor function by a complex combination of mechanisms including direct phos... of the multiprotein signaling complex. D1-Like Receptor ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
5 INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE Olfactory Receptor Interactions
 

Summary:  receptors, and A2A adenosine receptor. These four receptors were further- more found... - tor, coexpression with specific partner receptors can form heteromeric receptor complexes with greatly... ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
6 Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional Significance
 

Summary:  GPCRs (A1, A2A, A2b, and A3), whereas ATP activates P2X receptors, which are ion channels, as well... . (2003) Adenosine A2A-dopamine D2 receptor- receptor heteromerization: qualitative and quantitative... ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
7 Copyright C Blackwell Munksgaard 2002 Traffic 2002; 3: 866877
 

Summary:  , Strnad J, Pausch MH, Hadcock JR. Pharmacological char- acterization of the rat A2a adenosine receptor... -arrestin-dependent formation of beta2 adrenergic receptor- Src protein kinase complexes. Science 1999;283:655­661. 33. Mc... trafficking of G protein-coupled ...

  

Source: Bourne, Henry - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
8 Enhancement of the surface expression of G protein-coupled receptors
 

Summary:  receptors [49], Usp4, which increases plasma membrane expression of adenosine A2A receptors [50], ATBP50... surface level of the A2a receptor. Mol. Pharmacol. 69, 1083­1094 51 Wruck, C.J. et al. (2005) ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
9 Bruce N. Cronstein, MD You Are Not Arthur Conan Doyle
 

Summary:  A2A receptors in fibrosis in tissues outside of the skin is less clear... laboratory and others indicate that adenosine A2A receptors play an important role... adenosine ...

  

Source: Wang, Da-Neng - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University

 

Collection: Biology and Medicine

 
10 The concept of purinergic neurotransmission was pro-posed in 1972 (REF. 1), after it was shown that adenosine
 

Summary:  disorders, highlighting specific purinergic receptor subtypes, most notably A2A , P2X4 and P2X7 ,that might... in rodents, which is antagonised by caffeine. A2A receptors in the nucleus accumbens mediate this locomotor... . ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
11 J Physiol 588.1 (2010) pp 9399 93 SYMPOSIUM REVIEW
 

Summary:  adenosine A2A receptors are essential for inducing LTP of NMDA-EPSCs (Rebola et al. 2008). A2A receptors may... of mossy fibres lead to the activation of NMDA, mGluR5 and adenosine ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
12 REVIEW ARTICLE Chemokine receptors and other G protein-coupled receptors
 

Summary:  of the A2A adenosine receptor (Fig. 3d) in complex with an inverse agonist as well as an additional b2... of invertebrate rhodopsin, b1-adrenergic and b2-adrenergic receptors and the A2A-adenosine ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
13 Olfactory receptor trafficking to the plasma membrane C. F. Bush and R. A. Hall*
 

Summary:  A2a receptors, were all found to signifi- cantly enhance the plasma membrane localization of M71... performed in heterologous cells and it is not clear whether b2-adrenergic, P2Y1, P2Y2, and A2a receptors... of b2-adrenergic, ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
14 Purine and pyrimidine receptors G. Burnstock
 

Summary:  by ectonucleotidases. Four subtypes have been identified, A1, A2A, A2B and A3 receptors. P2 receptors are activated... different P1 receptor subtypes, A1, A2A, A2B and A3, have been cloned and charac- ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
15 Purine and pyrimidine receptors G. Burnstock
 

Summary:  , shortly after, the A3 subtype was identified [21]. Four different P1 receptor subtypes, A1, A2A, A2B and A... transmembrane domain. Polymorphisms have been observed in the A1 and the A2A receptors. P1 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
16 NMDA receptor subunit gating uncovered Alasdair J. Gibb
 

Summary:  order to arrive at the A2Rsf state that is then followed by channel opening (dashed box). A + R A2 A2 k... * AR Channel closed Closed Open A + R A2 A2 A2 k­1 2k+1 R RD1 RD2 ...

  

Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
17 Relating NMDA Receptor Function to Receptor Subunit Composition: Limitations of the Pharmacological Approach
 

Summary:  antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem... ) obtained evidence for a much more complex situa- tion, in which both receptor subtypes are able to generate... Commentary Relating NMDA ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
18 Purinoceptors on Neuroglia Alexei Verkhrasky & Oleg A. Krishtal &
 

Summary:  to several families of Gi and Go proteins. Four types of adenosine receptors (A1, A2A, A2B and A3... , induced [Ca2+ ]i elevation via activation of A2A receptors [77]. In cultured mouse astrocytes adenosine... -dependent ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
19 Oligomeric forms of G protein-coupled receptors (GPCRs)
 

Summary:  found in crystals of engineered human b2-adrenergic receptor [29] and an engineered human A2A adenosine... ­1265 30 Jaakola, V.P. et al. (2008) The 2.6 angstrom crystal structure of a human A2A adenosine receptor... -coupled ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
20 Conserved waters mediate structural and functional activation of family A (rhodopsin-like)
 

Summary:  , engineered A2A-adenosine, 1- and 2-adrenergic receptors, permits comparative analysis of features common... (omitting the T4 lysozyme amino acid sequence present in mutant 2-adrenergic receptor and A2A... identity, mutant ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine


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21 Provided for non-commercial research and educational use only. Not for reproduction, distribution or commercial use.
 

Summary:  pathway for diffusible ligands. The structure of an engi- neered human A2A adenosine receptor in complex... ­13], engineered expressed monoaminergic turkey 1AR [14], engineered expressed human A2A adenosine ...

  

Source: Sakmar, Thomas P. - Laboratory of Molecular Biology and Biochemistry, Rockefeller University

 

Collection: Biology and Medicine

 
22 *National Institute of Child Health and Human
 

Summary:  - prises the A1 , A2A , A2B and A3 adenosine receptors, which were identified by convergent data from... and locomotor depressant effects85 . The most well-known signal transduction mecha- nism for A2A receptors... is the ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
23 BRADSHAW 978-0-12-374145-5 00388 Multi-Pass Receptors
 

Summary:  - neered human A2A adenosine receptor in complex with the subtype specific antagonist ZM241385 provides... a number of additional surprises. The ligand binds to the A2A ade- nosine receptor in an ...

  

Source: Sakmar, Thomas P. - Laboratory of Molecular Biology and Biochemistry, Rockefeller University

 

Collection: Biology and Medicine

 
24 Current Pharmaceutical Design, 2009, 15, 000-000 1 1381-6128/09 $55.00+.00 2009 Bentham Science Publishers Ltd.
 

Summary:  1, A2A, A2B, and A3 (see [53]). All P1 adenosine receptors couple to G proteins and, in common... and adenosine A1 receptors have also been shown to form func- tionally interactive heteromeric complexes. D. ATP... Publishers Ltd. Purinergic ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
25 Development/Plasticity/Repair Spinal Adenosine A2a Receptor Activation Elicits Long-
 

Summary:  Development/Plasticity/Repair Spinal Adenosine A2a Receptor Activation Elicits Long- Lasting... tyrosine kinases, the Trk receptors. Thus, we hypothesized that A2a receptor agonists would elicit phrenic... ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
26 The past two years have seen remarkable advances in the structural biology of G-protein-coupled receptors (GPCRs). Highlights have
 

Summary:  --the human 2 adrenergic receptor (2AR), the avian 1AR and the human A2A adenosine receptor--as well... bound to the antagonist cyanopindolol24 ; the human A2A adenosine receptor bound to the antagonist ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
27 TRENDS in Pharmacological Sciences Vol.22 No.4 April 2001 http://tips.trends.com 0165-6147/01/$ see front matter 2001 Elsevier Science Ltd. All rights reserved. PII: S0165-6147(00)01643-6
 

Summary:  , four subtypes of adenosine (P1) receptors were cloned [A1 , A2A , A2B and A3 (Ref. a)]. P2X receptor... DPCPX, CPX, XAC Gi (1­3): cAMP nerve terminals A2A Brain, heart, lungs, spleen CGS21680 KF17837, SCH... (ATP/ADP) ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
28 Associate editor: A.L. Morrow Regulation of GABAA receptor trafficking, channel activity,
 

Summary:  to primarily postsynaptic localization of a1/a2/ a3hg2 receptors, the same receptor subtypes are also abundant... of pentameric receptors (reviewed by Sieghart et al., 1999; Whiting, 1999). Additional structural complexity... . Whereas different a ...

  

Source: Luscher, Bernhard - Department of Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
29 Purinergic signalling: therapeutic potential* GEOFFREY BURNSTOCK
 

Summary:  receptors were cloned, namely A1, A2A, A2B and A3 and in 1985, Burnstock and Kennedy proposed a basis... . Blockade of A2A (P1) receptors antagonises parkinsonian tremor in the rat tacrine model by actions... on specific ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
30 Progress in Neurobiology 70 (2003) 387407 Kainate receptors and synaptic transmission
 

Summary:  Progress in Neurobiology 70 (2003) 387­407 Kainate receptors and synaptic transmission James E... - and presynaptic roles for kainate receptors, which are a subtype of the ionotropic glutamate receptors. Kainate... receptors contribute to excitatory postsynaptic currents in many regions of the central nervous ...

  

Source: Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
31 The past two years have seen remarkable advances in the structural biology of G-protein-coupled receptors (GPCRs). Highlights have
 

Summary:  --the human 2 adrenergic receptor (2AR), the avian 1AR and the human A2A adenosine receptor--as well... ; the human A2A adenosine receptor bound to the antagonist ZM241385 (ref. 25); and bovine ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
32 Bovine Papillomavirus E5 Protein Induces the Formation of Signal Transduction Complexes Containing Dimeric Activated
 

Summary:  , activated PDGF receptor complexes were separated from monomeric, inactive receptor. Rapidly sedimenting... the major contribution to the increased sedimentation rate of the activated receptor complexes. Pairwise... of multiprotein, acti- vated PDGF receptor ...

  

Source: DiMaio, Daniel - Departments of Genetics & Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
33 Perspectives in Pharmacology P2 Purinergic Receptors: Modulation of Cell Function and
 

Summary:  this response. AMP gives rise to adenosine, which acti- vates the various P1 receptors (A1, A2A, A2B, A3... indicates that P2X receptors are equal in their complexity to other LGICs. The symmetrical structures... of complexity in understanding P2 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
34 UCB Pharma research day--25 October 2007 `Glia-neuron interactions and purinergic receptors
 

Summary:  . In the early 1990s, P1 and P2 receptors were cloned and characterised: four P1 receptor subtypes (A1, A2A, A2B... UCB Pharma research day--25 October 2007 `Glia-neuron interactions and purinergic receptors... neurotransmitters acting through glial metabotropic ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
35 Agonist-induced polarized trafficking and surface expression of the adenosine 2b receptor in intestinal epithelial cells: role of SNARE proteins
 

Summary:  of cellular functions by interacting with specific cell surface G protein-coupled receptors (A1, A2a, A2b... receptor on which it acts (4, 8, 26). For example, A2a receptors in the synovial tissue have ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
36 doi:10.1152/ajpcell.00025.2006 291:254-265, 2006. First published Mar 29, 2006;Am J Physiol Cell Physiol
 

Summary:  of this process are known. Western blot analysis established that all four aden- osine receptors (A1, A2a, A2b... membrane of the umbrella cell layer, whereas A2a, A2b, and A3 receptors were localized intracellularly... ...

  

Source: Apodaca, Gerard - Departments of Medicine & Cell Biology and Physiology, University of Pittsburgh

 

Collection: Biology and Medicine

 
37 G protein-coupled receptors (GPCRs) are the largest family of transmembrane proteins in vertebrates and they
 

Summary:  of type 1 angiotensin II receptor (AGTR1) can recruit a complex of JAK2 and tyrosine phosphatase non-receptor... -containing protein 2; mGluR, metabotropic glutamate receptor; MHC, major histocompatibility complex; MPP3, MAGUK p55... transporting protein; SNX1, sorting nexin 1; SSTR3, ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
38 Complex expression of natural killer receptor genes in single natural killer cells ZAHEED HUSAIN,*{{ CHESTER A. ALPER,{1 EDMOND J. YUNIS*{ &
 

Summary:  Complex expression of natural killer receptor genes in single natural killer cells ZAHEED HUSAIN... 19q13.4 in the leucocyte receptor complex and those for CD94/NKG2 are located on chromosome 12.p13... as non- stochastic mechanisms of NK receptor gene expression may explain the formation ...

  

Source: Alper, Chester A. - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
39 For personal use only. Not to be reproduced or distributed without permission from Prous Science. Drug News Perspect 16(3), April 2003 2003 Prous Science CCC: 02140934/2003 133
 

Summary:  (A 1, A2A, A2B, A3), are activated by adenosine. 1 There are two distinct families of receptors... ,38 Mice lacking the adeno- sine A2A receptor were found to have an increase in heart rate and high blood... pressure (as well ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
40 Glycosylation of b1-adrenergic receptors regulates receptor surface expression and dimerizationq
 

Summary:  the b2-adrenergic receptor [15], a2A-adrenergic re- ceptor [30], and dopamine D1 receptor [31]. Con... Glycosylation of b1-adrenergic receptors regulates receptor surface expression and dimerizationq... 30322, USA Received 29 August 2002 Abstract ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine


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41 Role of delivery and trafficking of d-opioid peptide receptors in opioid
 

Summary:  the surface expression of DOP receptors. These receptors form complexes with MOP receptors (MORs) on the cell... , which form heteromeric complexes with MOP receptors on the cell surface of neurons. The activated DOP... receptor in a heteromeric ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
42 EDITED B'r' Bertha K. Madras Harvard Medical School
 

Summary:  , and serotonin (5-HT3) receptors. Currently, 12 neu- ronal nAChR subunits have been identified (a2--a1 0 and 132... nicotinic receptors must coassemble with MuSK and rapsyn to stabilize the receptor complex, as well... Francisco #12;Neuronal ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
43 nature neuroscience volume 1 no 3 july 1998 185 Recent studies suggest that tyrosine kinases are important for
 

Summary:  . p 1a/2A (10), P 1aC744,798A/2A (5), l 1b/2A (9), L 1bm207­211/2A (6). (d) Correlation between... in size than those of other receptor subunits and may be involved in complex interactions with other... -term potentiation ...

  

Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
44 CO-IMMUNOPRECIPITATION AS A STRATEGY TO EVALUATE
 

Summary:  , and codesensitization of adenosine A2A receptors and dopamine D2 receptors. J Biol Chem 277:18091­18097. Hu LA, Tang Y... -dependent dissociation of oligomeric complexes of G protein- coupled cholecystokinin receptors demonstrated in living... ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
45 Proc. Natl. Acad. Sci. USA Vol. 95, pp. 1524115246, December 1998
 

Summary:  . These results indicated that the E5 protein induced PDGF receptor activation by forming a stable complex... trans-phosphorylation of receptor molecules in the dimeric complex, stimulation of the intrinsic... complex with the activated PDGF receptor in transformed ...

  

Source: DiMaio, Daniel - Departments of Genetics & Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
46 Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation
 

Summary:  ,23­25 and it is currently recognised that there are four subtypes of P1 receptors (A1, A2A, A2B and A3), seven subtypes of P... feedback (iv) Metabolic phenotype: increased insulin and glucagon secretion103­106 A2A (i) Behavioural... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
47 J Physiol 586.14 (2008) pp 33073312 3307 TOPICAL REVIEW
 

Summary:  in purinergic signalling 3309 purines and pyrimidines have been identified: P1 adenosine receptors (A1, A2A, A2B... ; and the complex actions mediated by P2X7 receptors. Some desirable areas for further research are also discussed... . For example, is pannexin 1 part ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
48 REVIEW ARTICLE The journey to establish purinergic signalling in the gut
 

Summary:  cloned, namely, A1, A2A, A2B, and A3. Seven subtypes of P2X receptors have been identified... and P2Y12 receptors were demonstrated on enteric neurons. Differential gene expression of A1, A2A, A2B... of adenosine A1, ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
49 STUDIES ON THE ROLE OF THE N-TERMINAL DOMAIN OF NR1 IN THE REDOX MODULATION OF NR2A-CONTAINING NMDA RECEPTORS
 

Summary:  -CONTAINING NMDA RECEPTORS by Greta Ann Herin B.S. in Psychology, Kansas State University, 1993 B... IN THE REDOX MODULATION OF NR2A-CONTAINING NMDA RECEPTORS Greta Ann Herin, PhD University of Pittsburgh, 2003... The NMDA receptor is the subject of intense study due to its critical role in many neuronal processes

  

Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh

 

Collection: Biology and Medicine

 
50 Purinergic signalling in the nervous system: an overview
 

Summary:  adenosine receptors A1, A2A, A2B and A3 are G- protein coupled (Figure 1). Typically, A1 and A3 couple... to the Gi/o family of G proteins inhibiting cyclic AMP (cAMP) production, whereas A2A and A2B stimulate c... , D-60439, Frankfurt am Main, ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
51 Pharmacology of Pain edited by Pierre Beaulieu, David Lussier, Frank Porreca, and Anthony H. Dickenson
 

Summary:  as purines [26,128] (see Table I). Four subtypes of P1 receptors have been cloned--A1, A2A, A2B, and A3 (see... receptors lead to suppression of pain signaling, while A2A receptors lead to pain ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
52 Draft: 3/12/2009 142:225 Growth Factor Receptor Signaling
 

Summary:  Draft: 3/12/2009 142:225 Growth Factor Receptor Signaling Outline: 1. Growth factor receptor... protein tyrosine kinase (PTK) signaling (J. Koland) a. Overview of PTK superfamily family · Nonreceptor/receptor... PTKs · Oncogene-Protooncogene relationships b. Receptor PTK signal transduction mechanisms · ...

  

Source: Iowa Center for Gene Therapy

 

Collection: Biotechnology ; Biology and Medicine

 
53 ASSOCIATE EDITOR: DIANNE M. PEREZ The Significance of G Protein-Coupled Receptor
 

Summary:  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 925 4. A2a-adenosine receptor structure... (Warne et al., 2008, 2011), A2a-adenosine (Jaakola et al., 2008; Xu et al., 2011), chemokine C... ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
54 Purinergic signalling *Geoffrey Burnstock
 

Summary:  /ADP, respectively, was proposed (Burnstock, 1978). Four subtypes of P1 receptors have been cloned, namely A1, A2A, A... . Adenosine, via A2A receptors, has a protective effect in a rat model of Parkinson's disease, perhaps... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
55 Desensitized nicotinic receptors in brain Hai Wanga,*, Xiulan Sunb
 

Summary:  subtypes because they contain no g, y or e subunits, and consist of various complements of a2­a10 and h2­h4... subunits [153]. Additionally, a2­a10 and h2­h4 subunits have been identified and cloned from human brain... receptors and ...

  

Source: Cooper, Robin L. - Department of Biology, University of Kentucky

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
56 Eph receptor tyrosine kinases and ephrins have been identified in organisms ranging from sponges to flies and worms to chick,
 

Summary:  , but also to several other targets in the forebrain [42·,54]. The conserved module of graded ephrin-A2/A5... structure of an Eph receptor- ephrin complex. Nature 2001, 414:933-938. These papers [12,13··,14··] describe... - ically organized retinal projections contain a conserved ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
57 JOURNAL OF CELLULAR PHYSIOLOGY 200:309317 (2004) Significance of N-Methyl-D-Aspartate (NMDA)
 

Summary:  a prominent role within the central nervous system (CNS). NMDA receptors are heteromeric complexes comprising... . Although NR2(A-D) subunits are innately involved in forming the heteromeric complexes of the NMDA receptor... and Taichman, 1994). These suprabasal cells are also found to express atypical ...

  

Source: Bear, Mark - Picower Institute for Learning and Memory & Department of Brain and Cognitive Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
58 Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and co-localization with the metabotropic glutamate receptor 5 in the striatum
 

Summary:  Title Page Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and co... ; Accepted: Aug 12, 2011 #12;Abstract The adenosine A2A receptor (A2AR) is a potential drug target... neuromodulator that ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
59 This article was originally published in the Encyclopedia of Neuroscience published by Elsevier, and the attached copy is provided by Elsevier for the
 

Summary:  Encyclopedia of Neuroscience (2009), vol. 1, pp. 105-113 Author's personal copy #12;A2A (P1) receptors... that intravenous injection of ATP into cats caused complex effects that affected both peripheral and central... ,b-meATP), whichproduces selec- tive desensitization of the ATP ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
60 The Glutamate Receptor Ion Channels RAYMOND DINGLEDINE,1
 

Summary:  strategy to conclude that homomeric GluR1 receptors could be tet- rameric complexes. Rosenmund et al. (1998... complexes represented by GluR2 plus either GluR1 or GluR3; very few solubilized receptors appeared... The Glutamate Receptor Ion Channels RAYMOND DINGLEDINE,1 KARIN BORGES, DEREK ...

  

Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine


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61 P2 receptors in cardiovascular regulation and disease David Erlinge & Geoffrey Burnstock
 

Summary:  phase hyperaemia mediated via A2A receptors on smooth muscle cells. Red blood cells as regulators... phase of the reactive hyperaemia as has been shown by infusion of adenosine deaminase or a selective A2A... REVIEW P2 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
62 q 2001 International Society for Neurochemistry, Journal of Neurochemistry, 76, 18871894 1887 Journal of Neurochemistry, 2001, 76, 18871894
 

Summary:  construct for the third intracellular loop of human a2A- adrenergic receptor (a2-AR-I3L) was generously... domains of the d opioid receptor Bo Cen,* Qingming Yu,* Jun Guo,² Yalan Wu,* Kun Ling,* Zhijie Cheng,* Lan... of Fudan University, Shanghai, China Abstract b-Arrestins regulate ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
63 Adenosine A3 receptor stimulation induces protection of skeletal muscle from eccentric exercise-mediated injury
 

Summary:  . Neither the A1 receptor agonist 2-chloro-N6 -cyclo- pentyladenosine (0.05 mg/kg) nor the A2A receptor... demonstrated a potent cytoprotective role of adenosine A1, A2A, and A3 receptors in ischemia and ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
64 Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression
 

Summary:  .R., Shanley, T.P., 2002. The A2A receptor mediates an endogen- ous regulatory pathway of cytokine expression... the P2X7 receptor complex negatively regulates P2X7 receptors. J. Biol. Chem. 278, 37344­37351. Y... Purinergic ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
65 GPCR agonist binding revealed by modeling and crystallography
 

Summary:  . Agonist binding to the adenosine A2A receptor. Binding predicted in the model of the NECA­A2AAR complex... screening: lessons learned from blind predictions of adenosine A2a receptor ...

  

Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
66 Purines and Sensory Nerves Geoffrey Burnstock
 

Summary:  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 Abstract P2X and P2Y nucleotide receptors are described on sensory neurons and their peripheral... and joints mediating reflex responses and nociception. Purinergic receptors on fibres in the dorsal spinal... been published ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
67 Structure based prediction of subtype-selectivity for adenosine receptor antagonists
 

Summary:  screening: lessons learned from blind predictions of adeno- sine A2A receptor complex. Proteins 78, 197e211... into the structural basis of ligand subtype selectivity within the family of adenosine receptors (AR: A1, ...

  

Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
68 Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells
 

Summary:  -coupled receptors ( 2A, M4, D2S, and A1) with the G Fig. 2. Oligomerization of a2A and M4 receptors on the plasma... of the receptor constructs (26). Furthermore, biochemical studies have proposed a pentam- eric complex between... in ...

  

Source: Xiang, Kevin Y. - Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign

 

Collection: Biology and Medicine

 
69 Growth differentiation factor 11 signals through the transforming growth factor-b receptor ALK5 to
 

Summary:  : ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­­ ­ ­ ­ ­ ­ ­ ­ ­+ + + + + + + + + + + + ­ ­ + + + + Type II: A2a A2b BRIITII A2a A2b BRIITII TGF-1 No receptor ALK4 ALK5 ALK7 No ligand Xnr1/Cripto GDF11... engage in a ...

  

Source: Ibáñez, Carlos - Department of Neuroscience, Karolinska Institutet

 

Collection: Biology and Medicine

 
70 BI-DIRECTIONAL MODULATION OF BED NUCLEUS OF STRIA TERMINALIS NEURONS BY 5-HT: MOLECULAR EXPRESSION AND
 

Summary:  AND FUNCTIONAL PROPERTIES OF EXCITATORY 5-HT RECEPTOR SUBTYPES J.-D. GUO,a S. E. HAMMACK,b R. HAZRA,a L. LEVITAc... stimuli. Application of 5-HT elicits complex postsynaptic re- sponses in BNSTALG neurons, which includes... is mediated by activation of postsynaptic 5-HT1A receptors. Here, we used a combination of in vitro whole

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
71 Stereoselectivity of 8-OH-DPAT toward the serotonin 5-HT1A receptor: Biochemical and molecular modeling study
 

Summary:  consistent with experimental data. Docking studies and the dynamics of ligand­receptor complexes emphasized... by comparative modeling approach and used to simulate the molecular dynamics of ligand­receptor complexes... simulations of receptor­ligand complexes ...

  

Source: Skolnick, Jeff - Center for the Study of Systems Biology, Georgia Institute of Technology

 

Collection: Chemistry ; Biology and Medicine

 
72 The role of ephrins and Eph receptors in cancer Hanna Surawska, Patrick C. Ma, Ravi Salgia*
 

Summary:  of ephrin oligomerization, distinct Eph receptor signaling complexes and biological effects can be induced... subclass of receptors and ligands, with EphA­ephrinA and EphB­ephrinB being the more favored complexes... complexes, attachment, and assembly responses [8], Eph ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
73 Genetics of caffeine consumption and responses to caffeine Amy Yang & Abraham A. Palmer & Harriet de Wit
 

Summary:  and A2A receptors (Daly et al. 1983). Adenosine receptors are G-protein-coupled receptors locat- ed... ubiquitously throughout the body. Of the four receptors that have been identified (A1, ...

  

Source: Das, Soma - Department of Human Genetics, University of Chicago; Ober, Carole - Committee on Genetics & Department of Human Genetics, University of Chicago

 

Collection: Biology and Medicine

 
74 Binding, gating, anity and ecacy The nature of the problem
 

Summary:  of ternary complex mechanisms What is known about the conformation of the receptor? Fusion of the receptor... -channel). Their mechanism postulated that binding of the agonist (A) to a receptor (R) resulted in a complex (AR) which... . The del Castillo-Katz mechanism was The agonist, A, ...

  

Source: Colquhoun, David - Department of Pharmacology, University College London

 

Collection: Biology and Medicine

 
75 New advances in production and functional folding of G protein-coupled receptors1 Jean-Louis Banres1,2
 

Summary:  and structure determination.74 For instance, the adenosine A2A receptor has been purified in a fully functional... of the rat neurotensin NTS1 or97 the cannabinoid CB2 receptors [20]. The human adenosine A2A ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
76 Modified Receptor Internalization upon Co-expression of 5-HT1B Receptor and 5-HT2B Agnes Janoshazi*, Maud Deraet*, Jacques Callebert, Vincent Setola, Silke Guenther, Bruno
 

Summary:  of GPCRs is the existence of complex intracellular regulatory mechanisms that modulate receptor... -localization was not consistent with agonist-induced 5-HT1B/5-HT2B receptor complex formation. Serotonin 5-HT2B and 5-HT1B... Mol #32656 p1 Modified Receptor Internalization upon ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
77 Bradfield; Mechanisms of Liver Carcinogenesis 18 UNIT VI: Nuclear Receptors: Zn Finger proteins and their roles in
 

Summary:  with retinoid X receptor (RXR). Wen ligand binds, the complexes release histone acetylases (that are locally... 1) Diffusion of steroid + 2) Binding of steroid to receptor HSP complex 3) Allosteric change... ) Binding of steroid to receptor HSP complex + 3) Allosteric ...

  

Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
78 Topology of Class A G Protein-Coupled Receptors: Insights Gained from Crystal Structures of Rhodopsins,
 

Summary:  ., 2004), and strokes and cere- bral hypoperfusion (altered adenosine A2A receptor function... 2A adenosine receptors have been solved at high resolution. This review focuses on the elucidation... Receptor versus Rhodopsin. ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
79 JOURNAL OF VIROLOGY, June 1994, p. 3582-3592 Vol. 68, No. 6 0022-538X/94/$04.00+0
 

Summary:  a complex with and activates the PDGF receptor and not the EGF receptor. Under conditions of transient... , the E5 protein preferentially forms a complex with the PDGF receptor. Therefore, we conclude... exist in a stable complex in transformed cell lines, implying ...

  

Source: DiMaio, Daniel - Departments of Genetics & Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
80 Special issue: Allosterism and Collateral Efficacy Conformational complexity of
 

Summary:  .sciencedirect.com #12;a2A adrenoceptor can still bind ligands after proteolytic cleavage of its loop structures [14... Special issue: Allosterism and Collateral Efficacy Conformational complexity of G... -protein-coupled receptors Brian K. Kobilka1 and Xavier Deupi2 1 Stanford University ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine


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Page:   1  2  3  4  5 
 
81 Physiology and Pathophysiology of Purinergic Neurotransmission
 

Summary:  receptors Four subtypes of P1 receptors have been cloned, namely, A1, A2A, A2B, and A3 (see Refs. 370, 423... , WRC-0571 Gi/Go2cAMP A2A Brain, heart, lungs, spleen NECA CGS 21680 CVT-3146 KF17837, SCH58261, ZM... homomultimer ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
82 INTERACTION BETWEEN ATP AND NERVE GROWTH FACTOR SIGNALLING IN THE SURVIVAL AND NEURITIC OUTGROWTH FROM
 

Summary:  for adenosine (A1, A2A, A2B and A3 subtypes, all G-protein-coupled) and P2 receptors for ATP (P2X ionotropic... ., 2001. Activation of protein kinase A and atypical protein kinase C by A2A adenosine receptors... ^18. Ongini, ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
83 JOURNAL OF VIROLOGY, Sept. 1995, p. 58695874 Vol. 69, No. 9 0022-538X/95/$04.00 0
 

Summary:  a stable complex with the endogenous platelet-derived growth factor (PDGF) receptor in rodent and bovine... that formed a complex with the PDGF receptor and induced receptor tyrosine phosphorylation but did not induce... receptor down- regulation PDGF ...

  

Source: DiMaio, Daniel - Departments of Genetics & Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
84 Perspectives in Pharmacology In Vivo Gene Modification Elucidates Subtype-Specific
 

Summary:  -adrenergic receptor expression. Mice with a deletion of the 2A- ( 2A-knockout [KO]), 2B- ( 2B-KO), or 2C... of a receptor in the adult, or the altered receptor expression could be a distant cause in a complex chain... , suggesting that ...

  

Source: Kable, Joe - Center for Cognitive Neuroscience & Department of Psychology, University of Pennsylvania

 

Collection: Biology and Medicine

 
85 Critical ReviewsTM in Neurobiology, 16(3)187224 [2004] 0892-0915/04 $20.00 2004 by Begell House, Inc. 187
 

Summary:  ligand but simply act to modulate the function properties of receptor complexes [Perez-Otano et al. 2001... , Inc. 187 Glutamate Receptor Gating Kevin Erreger,¹ Philip E. Chen,² David J.A. Wyllie,² & Stephen F... 30322-3090; kerrege@emory.edu ABSTRACT: Ionotropic glutamate receptors (iGluRs) mediate ...

  

Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
86 Characterization of Determinants of Ligand Binding to the Nicotinic Acid Receptor GPR109A (HM74A/PUMA-G)
 

Summary:  extracellular loop of the human A2a adenosine receptor are required for ligand recognition. Mol Pharmacol 49... Characterization of Determinants of Ligand Binding to the Nicotinic Acid Receptor GPR109A (HM74A... -protein-coupled receptor GPR109A (HM74A/PUMA-G) has ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
87 New advances in production and functional folding of G-protein-coupled
 

Summary:  . 29, No. 7 #12;structure determination. For instance, the adenosine A2A receptor has been purified... NTS1 and cannabinoid CB2 receptors [20]. The human adenosine A2A receptor has been highly expressed... ...

  

Source: Institut de Biologie Physico-Chimique CNRS, Physico-Chimie Moléculaire des Membranes Biologiques

 

Collection: Chemistry ; Biology and Medicine

 
88 Probing the role of the cation interaction in the binding sites of GPCRs using unnatural amino acids
 

Summary:  . Jaakola VP, et al. (2008) The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound... methodology for unnatural amino acid incorporation to probe drug­ receptor interactions in functional G... protein-coupled receptors (GPCRs), evaluating the ...

  

Source: Lester, Henry - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
89 Recombinant Production and Properties of Binding of the Full Set of Mouse Secreted Phospholipases A2 to the Mouse M-Type Receptor
 

Summary:  ) 685-8665. E-mail: gelb@chem.washington.edu. 1 Abbreviations: sPLA2, secreted phospholipase A2 [a... 2 to the Mouse M-Type Receptor Morgane Rouault,,§ Catherine Le Calvez,,§ Eric Boilard,,§ Fanny... distinct functions by acting as an enzyme or ligand for specific soluble proteins or ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
90 A Dominant-Negative Human Growth Hormone-Releasing Hormone (GHRH) Receptor Splice Variant
 

Summary:  -type receptor signaling. The wild-type and truncated GHRH receptor proteins form a complex. Stably transfected... the truncated receptor can form a complex with the wild-type receptor and inhibit normal GHRH binding, thereby... receptors form a ...

  

Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
91 Cellular/Molecular Neurosteroid Access to the GABAA Receptor
 

Summary:  ,alargepartoftheresurgenceresultsfrombicucullineunbindingbeforesteroiddeparture. A2, A3, The offset current was partly inhibited by a brief wash with 500 M -cyclodextrin (CDX... ) of a cell subjected to the protocol in A1. ...

  

Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
92 Membrane Associated Non-receptors and Morphogen Gradients
 

Summary:  non-receptor mediated ligand degradation. By allowing degradation of ligand-non-receptor complexes... to (signaling) cell receptors. Concentration gradients of morphogen-receptor complexes are known to be respon... gradients of different ...

  

Source: Wan, Frederic Yui-Ming - Department of Mathematics, University of California, Irvine

 

Collection: Mathematics

 
93 Oestradiol Increases Phosphorylation of a Dopamine-and Cyclic AMP-Regulated Phosphoprotein (DARPP-32) in Female Rat Brain
 

Summary:  , Greengard P, Fisone G. Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP... a conformational change in their receptors that may allow the activated steroid-receptor complex to bind to DNA... , but not following treat- ...

  

Source: Blaustein, Jeffrey D. - Center for Neuroendocrine Studies, University of Massachusetts at Amherst

 

Collection: Biology and Medicine

 
94 Assembly and trafficking of nicotinic acetylcholine receptors NEIL S. MILLAR & PATRICIA C. HARKNESS
 

Summary:  . Nicotinic receptors are complex pentameric transmembrane proteins which are assembled from a large family... -assembled sub- units [44Á47]. Neuronal nAChR subunits such as a2, a3, a4, b2 and b4 are able, at least... oocytes de- monstrate that functional heteromeric nAChRs are generated ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
95 Proc. Natl. Acad. Sci. USA Vol. 92, pp. 7749-7753, August 1995
 

Summary:  - nohistochemically in sections ofneonatal brain and DRG using antibodies specific for the a,, a2, a5, and 32... . These cells display a homogeneous subunit repertoire (a2, a3, 13, 72) and are therefore suitable... subunit of other ligand-gated ion channels was ...

  

Source: Luscher, Bernhard - Department of Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
96 Purinergic signalling in autonomic Alexander V. Gourine1
 

Summary:  -receptor-mediated) and facilitatory (A2A-receptors-mediated) presynaptic actions of adenosine... , adenosine evokes slow EPSP-like excitatory responses mediated via A2A receptors [49]. Adenosine is also... ­1409 49 Gao, N. et ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
97 Palmitoylation of the EGF Receptor Impairs Signal Transduction and Abolishes High-Affinity Ligand Binding
 

Summary:  ., and Yokoyama, S. (2002) Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor... Palmitoylation of the EGF Receptor Impairs Signal Transduction and Abolishes High-Affinity Ligand... : The intracellular juxtamembrane domain of the EGF receptor has been shown to be involved in the ...

  

Source: Pike, Linda J. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis

 

Collection: Biology and Medicine

 
98 Spinal neurons are sensitized following stimuli that activate nociceptors. This central sensitization is
 

Summary:  /C) No 5-HT2A or 5-HT2C 3/3 DOI (5-HT2A/C) Spiperone (5-HT1A,2A) Yes 5-HT2C 3/3 MK-212 (5-HT2C) -- Yes 5-HT... -methyl-D-aspartate (NMDA) receptor activation is required for their induction (Randic et al. 1993; Liu & Sandkühler, 1995... also appear to be NMDA receptor dependent (Woolf ...

  

Source: Hochman, Shawn - Department of Physiology, Emory University

 

Collection: Biology and Medicine

 
99 ABBREVIATIONS: NMDA, N-methyl-D-aspartic acid; ACPD, 1-aminocyclopentane-1 ,3-dicarboxylic acid; AMPA,a-amino-3-hydroxy-5-methyli-soxazole-4-propionic acid; BAPTA, 1 ,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid; DMSO, dimethylsulfoxide; DNQX, 6
 

Summary:  : NMDA receptor (NR)1 A/2A, 29 nM; NR1 A/2B, 300 nM; NR1A/2C, 120 nM; NR1A/2D, 1500 nM. Measurement of EC... the receptors expressed by rat brain poly(AY RNA, NR1A/2A and NR1AJ2B responses showed progressive run-down upon... ...

  

Source: Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
100 The Mutant Growth Hormone-Releasing Hormone (GHRH) Receptor of the Little Mouse Does Not
 

Summary:  binding, the GHRH-receptor complexes were cross-linked with long-wave UV, SDS denatured, analyzed by gel... . 5068 GHRH RECEPTOR OF THE LITTLE MOUSE Endo · 1999 Vol 140 · No 11 #12;and complex glycosylated forms... of the wild-type GHRH receptor are accessible in our permeabilized ...

  

Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine


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