| Sample search results for: aav5 vector facilitates |
| 1 | JOURNAL OF VIROLOGY, Apr. 2004, p. 33613371 Vol. 78, No. 7 0022-538X/04/$08.00 0 DOI: 10.1128/JVI.78.7.33613371.2004 | ||
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Summary: serotype 5 (AAV5) requires sialic acid on host cells to bind and infect. Other parvoviruses, including... . In contrast to AAV5, AAV2 does not bind sialic acid, but rather binds heparan sulfate proteo- glycans at its... to cell receptor attachment, we determined the structure of ... |
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Source: Baker, Timothy S. - Department of Chemistry and Biochemistry, University of California at San Diego |
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Collection: Biology and Medicine |
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| 2 | JOURNAL OF VIROLOGY, Aug. 2002, p. 76517660 Vol. 76, No. 15 0022-538X/02/$04.00 0 DOI: 10.1128/JVI.76.15.76517660.2002 | ||
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Summary: and ITR of AAV5 fail to cross-complement those of AAV1 to -4 (6). Vectors constructed from AAV2, AAV3, AAV... variation among the AAV serotypes (7, 30). Unlike AAV2, AAV 2/6 and AAV5 vectors are not inhibited by hep... expression from AAV2- or ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 3 | original article The American Society of Gene Therapy Molecular Therapy vol. 17 no. 2, 285293 feb. 2009 285 | ||
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Summary: label. Both rAAV5 and rAAV1 vectors were capable of transducing a subset of long-lived Clara cells... results demonstrate that the rAAV1 and rAAV5 vectors are indeed able to transduce epi- thelial slow... expression in rAAV1Cre, rAAV2Cre, or ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 4 | original article 594 www.moleculartherapy.org vol. 18 no. 3, 594600 mar. 2010 | ||
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Summary: -CB-FL and rAAV5-CB-RL vec- tors (the same vectors used for the chimp studies). Figure 2c shows... AAV1 and rAAV5 vectors in the chimpanzee airway in vivo As in vitro polarized airway epithelia cannot... of luciferase activity from each vector was ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 5 | Current Gene Therapy, 2003, 3, 281-304 281 1566-5232/03 $41.00+.00 2003 Bentham Science Publishers Ltd. | ||
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Summary: the development of AAV vector production strategies involving Rep or ITR elements from AAV-5. Within the AAV-2... of AAV- 5-based vectors. Results from vector production indeed indicate that particle titers from helper... of AAV-2 ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 6 | JOURNAL OF VIROLOGY, Jan. 2005, p. 364379 Vol. 79, No. 1 0022-538X/05/$08.00 0 doi:10.1128/JVI.79.1.364379.2005 | ||
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Summary: and AAV-5 to generate a novel hybrid ITR vector genome. This hybrid ITR viral vector contained one AAV-2... ITR and one AAV-5 ITR at opposite ends of the viral genome. Hybrid ITR vectors functionally transduced... a single encoded transgene at an ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 7 | This is an Accepted Article that has been peer-reviewed and approved for publication in the Journal of Neurochemistry, but has yet to undergo copy-editing and proof correction. Please | ||
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Summary: in vivo DOPA production and studies of ectopic DA synthesis using rAAV5 vectors in Parkinsonian rats Tomas... and metabolism. For this purpose, we injected a fixed amount of rAAV5-TH vector and increasing amounts of rAAV5... ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 8 | JOURNAL OF VIROLOGY, Mar. 2002, p. 20432053 Vol. 76, No. 5 0022-538X/02/$04.00 0 DOI: 10.1128/JVI.76.5.20432053.2002 | ||
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Summary: for development as a gene delivery vector (2, 5). Although less is known about AAV-5 molecular biology... for rAAV-2 and pseudotyped rAAV-5 (rAAV-2cap5) facilitated direct evaluation and com- parison... - fer vector for a longer time than ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 9 | HUMAN GENE THERAPY 19:7181 (January 2008) Mary Ann Liebert, Inc. | ||
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Summary: of the spinal cord (Kuchler et al., 2002). MATERIALS AND METHODS rAAV vector production rAAV5 virus production... demonstration of multisegmental spinal delivery of rAAV5-derived trophic fac- tors facilitated by anterograde... to transport recombinant ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 10 | Species-Specific Differences in Mouse and Human Airway Epithelial Biology of Recombinant | ||
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Summary: infection with rAAV5 vectors were significantly different between mouse and human ALI airway epithelia. Our... in polarized human airway epithelia demonstrate that both rAAV2 and rAAV5 vectors have similar levels of apical... in intracellular trafficking between ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 11 | Directed evolution of adeno-associated virus to an infectious respiratory virus | ||
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Summary: distinct receptors, AAV2 (heparan sulfate) and AAV5 (sialic acid) (1316). Subsequent selection... combined 2 divergent serotypes that use distinct receptors, AAV2 and AAV5, by subjecting the cap genes... revealed a single AAV variant, AAV2.5T, which is a chimera between AAV2 (aa1128) and ... |
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Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 12 | JOURNAL OF VIROLOGY, July 2003, p. 73617366 Vol. 77, No. 13 0022-538X/03/$08.00 0 DOI: 10.1128/JVI.77.13.73617366.2003 | ||
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Summary: of new AAV serotype vectors have demon- strated that both rAAV-5 and rAAV-6 are capable of effi- ciently... 2/5 nomenclature were pseudotyped with AAV-5 capsid as previously described (13). Luciferase vectors... -Strand Genome Conversion of Adeno-Associated Virus Type ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 13 | A Two-hybrid Screen Identifies Cathepsins B and L as Uncoating Factors for Adeno-associated Virus 2 | ||
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Summary: . Firstly, when the assay was conducted with AAV5(gfp), we only observed a decrease in vector transduction... cathepsin B or L, whereas no significant change was seen with the AAV5 vector (Figure 4b), confirming... 40 30 20 10 0 0 20 M 40 M Ca074-Me AAV2 AAV2AAV8 ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 14 | JOURNAL OF VIROLOGY, 0022-538X/01/$04.00 0 DOI: 10.1128/JVI.75.16.76627671.2001 | ||
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Summary: as a gene therapy vector. Detailed sequence comparisons indicate that the AAV-5 capsid proteins are sig... that recombinant AAV-5 vectors might have a unique niche in gene therapy applications. For example, AAV-5 likely... ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 15 | JOURNAL OF VIROLOGY, Jan. 2006, p. 426439 Vol. 80, No. 1 0022-538X/06/$08.00 0 doi:10.1128/JVI.80.1.426439.2006 | ||
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Summary: , which hampered analyses of the contribution of AAV-5 ITRs to vector function in the past and represented... be exploited by flanking vector DNAs with AAV-5 ITRs, as was previously suggested (17, 52). A second example... (10 l; see above). Cloning of AAV genotype ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 16 | JOURNAL OF VIROLOGY, Mar. 2004, p. 28632874 Vol. 78, No. 6 0022-538X/04/$08.00 0 DOI: 10.1128/JVI.78.6.28632874.2004 | ||
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Summary: . Recently, it has been reported that rAAV-5 vectors more effectively transduce murine lungs. Intranasal... also observed with rAAV-5 vectors; however, the overall maximal expression in the presence of LLn... - tion and transduction of recombinant adeno-associated ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 17 | 2011NatureAmerica,Inc.Allrightsreserved. nature neurOSCIenCe advance online publication | ||
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Summary: cortex. All AAV5 vectors had a titer of 1012 particles per ml. We also injected one site in monkey B... a lentiviral vector instead of AAV5 (or a low virus titer instead of a high virus titer), or by enhancing... pseudotyped with serotype 5 (here referred to as ... |
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Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 18 | NATURE NEUROSCIENCE VOLUME 14 | NUMBER 3 | MARCH 2011 387 T E C H N I CA L R E P O R T S | ||
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Summary: in somatosensory cortex. All AAV5 vectors had a titer of 1012 particles per ml. We also injected one site in monkey... strong promoter (like hThy-1), by using a lentiviral vector instead of AAV5 (or a low virus titer instead... pseudotyped with serotype 5 (here ... |
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Source: Shenoy, Krishna V. - Neurosciences Program & Department of Electrical Engineering, Stanford University |
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Collection: Engineering ; Biology and Medicine |
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| 19 | Intrastriatal rAAV-Mediated Delivery of Anti-huntingtin shRNAs Induces Partial Reversal of Disease Progression | ||
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Summary: strategy was based on the use of recombinant adeno-associated virus serotype-5 (rAAV5) vectors to deliver... demonstrated that rAAV5 vectors can efficiently mediate the widespread and long-term expres- sion of transgenes... hemisphere. Injection of ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 20 | original article 2096 www.moleculartherapy.org vol. 17 no. 12, 20962102 dec. 2009 | ||
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Summary: has been achieved by an intravitreally injected AAV vector. Interestingly, AAV5 is apparently the only... cell types from the vitreous, with AAV5 mediating particularly remarkable expression in all retinal... for some AAV serotypes, and AAV2 uses heparan sulfate for cell recognition and ... |
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Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 21 | Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo | ||
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Summary: of rAAV5-HD6 and HD7 We generated rAAV serotype 5 (rAAV5) viral vectors expressing HD6 or HD7... of the hybridization signal of the mRNA expressed from each of the rAAV5 vectors were comparable among all mice (data... ENK, ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 22 | Helper Virus-Free, Optically Controllable, and Two-Plasmid-Based Production of Adeno-associated | ||
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Summary: -intensive preparation of an additional plasmid [e.g., 16]. In one study, AAV-2 vector pseudotyping with AAV-5 METHODdoi... , the only excep- tion being the AAV-5-based vector. This was, however, not surprising regarding the known... highest titers among all pRC ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 23 | Sites in the AAV5 capsid tolerant to deletions and tandem duplications Kaoru Hida a | ||
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Summary: ]. For example, AAV5 may be the vector of choice for gene ther- apy targeted for the lungs; it transduces... containing the AAV2 rep and Topo-AAV5 with wt or library cap, respectively, and a vector plasmid containing... Sites in the ... |
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Source: Gray, Jeffrey J. - Department of Biomolecular and Chemical Engineering, Johns Hopkins University; Ostermeier, Marc - Department of Biomolecular and Chemical Engineering, Johns Hopkins University |
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Collection: Biology and Medicine ; Biotechnology ; Chemistry |
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| 24 | Enhanced Preparation of Adeno-Associated Viral Vectors by Using High Hydrostatic Pressure to | ||
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Summary: ). Briefly, AAV2-GFP vector backbone, pHelper, and pXR5 (which expresses AAV5 Cap and an AAV5/AAV2 chimeric... and Goudsmit, 2001). In addition, AAV5 vectors are capable of enhanced gene delivery to tissues in which AAV2... , ... |
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Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 25 | Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display | ||
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Summary: transfer applications. RESULTS Phenotype of Transduced Cells rAAV1 and rAAV5 vectors have been reported... , including AAV1 and AAV5 [42,43]. In this study, we quantitatively evaluated three distinct rAAV vectors, r... cassette under the control of the synthetic CBA ... |
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Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison; Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 26 | Intracellular trafficking of adeno-associated viral and JF Engelhardt1,2,3 | ||
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Summary: -linked sialic acid45 Unknown AAV5 N-linked sialic acid45,46 PDGFR54 Intracellular trafficking of AAV vectors W... for AAV4 and AAV5. AAV5 primarily uses N-linked sialic acid for binding, whereas AAV4 preferentially uses... factor receptor (PDGFR) ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 27 | Unique Biologic Properties of Recombinant AAV1 Transduction in Polarized Human Airway Epithelia* | ||
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Summary: , treatment with proteasome inhibitors more significantly enhanced transduc- tion with rAAV2 and rAAV5 vectors... and rAAV5 vectors, despite near equivalent levels of viral uptake, suggested that rAAV1 intracellular... - thelia with proteasome inhibitors at the time of ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 28 | HUMAN GENE THERAPY 18:8187 (January 2007) Mary Ann Liebert, Inc. | ||
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Summary: ). In comparison with homologous AAV2 or AAV5 ITR vectors, hybrid 2:5-ITR vec- tors have been shown to less... AAV5 and AAV2 ITRs, and these two vector genotypes TRANS-SPLICING HYBRID-ITR AAV VECTORS 83 FIG. 2... demonstrate that AAV2 and ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 29 | JOURNAL OF VIROLOGY, Apr. 2005, p. 50475058 Vol. 79, No. 8 0022-538X/05/$08.00 0 doi:10.1128/JVI.79.8.50475058.2005 | ||
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Summary: resolution structures of AAV2 and AAV5 (40, 63), as well as those of the autonomous parvoviruses Aleutian... experiments with AAV5 have demonstrated improved binding and transduction * Corresponding author. Mailing... affinity is weaker (49). However, AAV3 also lacks R585 and R588. Transduction by AAV4 and ... |
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Source: Baker, Timothy S. - Department of Chemistry and Biochemistry, University of California at San Diego |
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Collection: Biology and Medicine |
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| 30 | SHORT COMMUNICATION Comparative biology of rAAV transduction in ferret, | ||
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Summary: AAV serotypes closely mirrors that observed in human epithelia (rAAV14 rAAV2DrAAV5), while transduction of mouse... epithelia was significantly different (rAAV14rAAV5brAAV2). Similarly, ferret, pig and human epithelia also... and rAAV5 transduction of human and mouse ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 31 | Neurobiology of Disease Positron Emission Tomography Imaging Demonstrates | ||
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Summary: - binant adeno-associated viral (rAAV5) vectors. Local striatal DOPA synthesis provided in this way results... and rAAV5GCH1 vectors reverses these changes, thus providing un- equivocal evidence that a functional... . The first group of animals received injection of ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 32 | HUMAN GENE THERAPY 16:11161123 (September 2005) Mary Ann Liebert, Inc. | ||
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Summary: epithelia were infected from the apical mem- brane with rAAV2 or rAAV5 CFTR-PTM vectors in the presence... . Levels of CFTR correction seen with rAAV2 (1.07 0.24 A) and rAAV5 (0.90 0.20 A) CFTR-PTM vectors were... -CF epithelia, and was similar for both rAAV2 and ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 33 | GENE THERAPY Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors | ||
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Summary: serotype vectors Initial vector AAV-1 AAV-2 AAV-3 AAV-4 AAV-5 AAV-6 AAV-1pv 1600 ND ND ND ND to 400 1600... the AAV-2 vector. Mingozzi et al20 reported up to 25-fold higher efficiency from AAV-5 in the murine liver... % of the maximum hFIX protein ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 34 | HUMAN GENE THERAPY 15:405413 (April 2004) Mary Ann Liebert, Inc. | ||
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Summary: vector genome (containing the ITRs/LacZ ex- pression cassette) into AAV5 or AAV8 capsids by cotransfec... -associated virus serotype 5 and 8 (AAV5LacZ, AAV8LacZ) carrying the LacZ reporter, and compared the transduction... , with significant levels of expression detectable at 1 week, ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 35 | Dual Therapeutic Utility of Proteasome Modulating Agents for Pharmaco-Gene Therapy of the | ||
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Summary: for the AAV2 vectors groups (Fig. 3B). Enhancement of vector-derived mRNA/ DNA ratios for the AAV5 vector... , rAAV2 vectors performed better than rAAV5 vectors. These findings support the notion that ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 36 | Adeno-associated viral vectors and stereotaxic | ||
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Summary: , AAV5, AAV8, AAV9, AAVDJ Photoreceptor Cells AAV5 Lung AAV9 Heart AAV8 Pancreas AAV8 Kidneys AAV2... Adeno-associated viral vectors and stereotaxic delivery Eric Washburn Vollum Viral Core washbure... types · ~4.7 kb wild type genome #12;AAV Life Cycle #12;Packaging Components of rAAV 1. ... |
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Source: Chapman, Michael S. - Department of Biochemistry and Molecular Biology, Oregon Health and Science University |
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Collection: Biology and Medicine |
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| 37 | 11/13/11 10:33 AMAbstract Print View Page 1 of 2http://www.abstractsonline.com/Plan/AbstractPrintView.aspx?mID=2...472c-8713-73eddce872b7&cKey=e99c3f48-6778-47ba-9f60-c17304239095 | ||
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Summary: -neuronal human promoters (hThy1, hSyn) and using AAV5 as the delivery vector, motivated by the translational... ., 2009; Lee et al., 2010). Here we report functionality of AAV5-CaMKII-C1V1 in macaque cortex. Light... advantages of AAV vectors which derive from their ... |
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Source: Shenoy, Krishna V. - Neurosciences Program & Department of Electrical Engineering, Stanford University |
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Collection: Engineering ; Biology and Medicine |
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| 38 | Copyright Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited. Gene therapy for hemophilia | ||
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Summary: that from an AAV2 vector in dogs with hemophilia B, while expres- sion from AAV5 was lower than that from... AAV2. Sim- ilarly, AAV5 or AAV8 vectors expressing human FIX were not more effective than AAV2 vectors... :875888. This paper ... |
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Source: Ponder, Katherine P. - Departments of Medicine & Biochemistry and Molecular Biophysics, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 39 | original article The American Society of Gene Therapy Molecular Therapy vol. 16 no. 10, 17031709 oct. 2008 1703 | ||
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Summary: AAV4 AAV6AAV5 AAV9AAV8 cA1 cA2 cA3 cA4 cB1 cB2 cB3 cB4 Figure 1 Amino acid sequences of shuffled... 9 AAV9AAV8AAV6AAV5AAV4AAV2 Figure 2 structural comparison of selected viral chimeras. Molecular... translate into novel gene-delivery properties distinct from the parent serotypes. ... |
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Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 40 | HUMAN GENE THERAPY 16:781791 (July 2005) Mary Ann Liebert, Inc. | ||
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Summary: hippocampal transductions of rAAV1 (A), rAAV2 (B), and rAAV5 (C) (1 1013 to 8 1013 vector genome copies... transduction with rAAV5-pseudo- typed vectors (Peden et al., 2004). Furthermore, intrastriatal rAAV2 injections... and ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 41 | Expert Review Designer Gene Delivery Vectors: Molecular Engineering and Evolution | ||
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Summary: , respectively (143,144). Likewise, Peden et al. have shown that AAV5 vector can transduce rat brain pre... , and AAV5 vectors to mouse skeletal muscle. Prior immunization with various serotypes did not significantly... ,77,79). ... |
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Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 42 | JOURNAL OF VIROLOGY, Oct. 2006, p. 98319836 Vol. 80, No. 19 0022-538X/06/$08.00 0 doi:10.1128/JVI.00878-06 | ||
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Summary: therapy vector. MATERIALS AND METHODS Plasmids. The AAV2, AAV5, AAV6, and AAV8 bait plasmids were con... factor receptor (PDGFR) (7, 15, 34). Like AAV5, AAV4 was also shown to interact with sialic acid; however... [AAV5], 442 to 1863 [AAV6], and ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 43 | HUMAN GENE THERAPY 18:344354 (April 2007) Mary Ann Liebert, Inc. | ||
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Summary: of AAV5 and AAV6 showed that whereas both vectors had high transduction rates in well... that is exposed to the virus. Sialic acid is required for AAV5 gene transfer (Wal- ters et al., 2001... ) and is an abundant sugar on the apical sur- face, consistent with the better performance of ... |
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Source: Miller, Dusty - Division of Human Biology, Fred Hutchinson Cancer Research Center |
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Collection: Biology and Medicine |
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| 44 | original article 2088 www.moleculartherapy.org vol. 17 no. 12, 20882095 dec. 2009 | ||
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Summary: variable efficiencies (AAV5).7,18 Additionally, recent work in the retina utilizing AAV vectors... reported for AAV4 and AAV5,7,8,18,22 though AAV4 transduces astrocytes only within the subventricular zone... , and reports of AAV5 transduc- tion ... |
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Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 45 | 11/13/11 10:34 AMAbstract Print View Page 1 of 2http://www.abstractsonline.com/Plan/AbstractPrintView.aspx?mID=2...472c-8713-73eddce872b7&cKey=3ac40567-8b18-4983-84a3-c744f50c82da | ||
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Summary: Abstract Program#/Poster#: 306.13/YY24 Presentation Title: Optogenetic projection targeting with AAV5... to label with unilateral injections of AAV5 in combination with the promoters hSyn and hThy-1 in premotor... traveling of AAV5 between cortex and thalamus. To ... |
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Source: Shenoy, Krishna V. - Neurosciences Program & Department of Electrical Engineering, Stanford University |
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Collection: Engineering ; Biology and Medicine |
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| 46 | original article 2114 www.moleculartherapy.org vol.15no.12,21142123dec.2007 | ||
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Summary: of bioelectric properties and susceptibil- ity to rAAV infection with rAAV1, rAAV2, and rAAV5 serotype vectors... ) Illustration of the proviral vector used to pseudo- type package into rAAV1, rAAV2, or rAAV5 capsids... with three rAAV sero- types (AAV1, AAV2, ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 47 | original article The American Society of Gene & Cell Therapy Molecular Therapy 1 | ||
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Summary: 27 Specifically, AAV1 and AAV5 sero- types have more favorable properties for reproducible production at high... /5, and AAV2/8 in the basal ganglia of nonhuman primates. We now pres- ent data showing that AAV1 and AAV5... for the dif- ferent serotypes. AAV 1 AAV 5 ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 48 | JOURNAL OF VIROLOGY, June 2004, p. 63446359 Vol. 78, No. 12 0022-538X/04/$08.00 0 DOI: 10.1128/JVI.78.12.63446359.2004 | ||
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Summary: vector after purification; right lane, rAAV5-GFP vector after purification. VOL. 78, 2004 PREIMMUNIZATION... as previously described (44). rAAV5-eGFP was a pseudotyped vector using the same transgene-containing plasmid... as the rAAV2 ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 49 | Current Gene Therapy, 2001, 1, 137-147 137 1566-5232/00 $20.00+.00 2001 Bentham Science Publishers Ltd. | ||
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Summary: trans-duction efficiency was achieved with rAAV4 and/or rAAV5 vectors in the ependymal cells... of the lateral ventricle compared to rAAV2 vectors. In addition, AAV5 was also able to transduce not only... ) Transduction of murine cerebellar neurons with recombinant ... |
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Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 50 | HUMAN GENE THERAPY 18:871880 (October 2007) Mary Ann Liebert, Inc. | ||
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Summary: the vectors with the AAV-5 capsid, which transduces photoreceptors more efficiently than AAV-2 (Yang et al... OPS promoter does not support reporter expression in RPE (Flannery et al., 1997), but because AAV-5 is known... - clei of transduced RPE. Scale bar: 50 m. ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 51 | The phosphorylation state of Ser-129 in human -synuclein determines neurodegeneration | ||
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Summary: expressing the AAV5 capsid gene. The final titers were 1.0 1013, 1.7 1013, and 0.9 1013 vector genome (vg... and in the ventral tegmental area (Fig. 1A). These data are in agreement with our findings that showed that rAAV5... with GFP (Fig. 3 AC). We also note that the use of ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 52 | 11/13/11 10:33 AMAbstract Print View Page 1 of 2http://www.abstractsonline.com/Plan/AbstractPrintView.aspx?mID=2...472c-8713-73eddce872b7&cKey=33a870a7-f4d8-4e91-b1a5-44f8d02f1076 | ||
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Summary: inhibitory opsin eNpHR3.0, under control of the CaMKII promoter using the AAV5 vector system, in squirrel |
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Source: Shenoy, Krishna V. - Neurosciences Program & Department of Electrical Engineering, Stanford University |
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Collection: Engineering ; Biology and Medicine |
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| 53 | Parvalbumin neurons and gamma rhythms enhance cortical circuit performance | ||
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Summary: R2eYFP AAV5 vectors were stereotactically injected into the cortex of PV::Cre transgenic mice... generation in vivo. We injected Camk2a (CaMKIIa)::ChR2eYFP and Cre-dependent eNpHReYFP AAV5... YFP AAV5 in prefrontal cortex. Blue light drove ... |
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Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 54 | JOURNAL OF VIROLOGY, June 2008, p. 58875911 Vol. 82, No. 12 0022-538X/08/$08.00 0 doi:10.1128/JVI.00254-08 | ||
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Summary: distinct serotypes, such as AAV-1 and AAV-2 (30) and pairwise combinations of AAV-1 through AAV-5 (62... different AAV serotypes were present in the lab (for AAV-2, AAV-4, and AAV-5) or kindly provided by James... AAV and AAV-5. The other seven cap genes were ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 55 | Molecular Engineering of Viral Gene Delivery Vehicles | ||
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Summary: been used to retarget Ad vectors to alternate receptors (44), and reovirus 1 protein facilitated sialic... incor- porated into virion particles during vector production, facilitating novel targeted gene deliv... 100-fold), thus facilitating the engineering of Ad ... |
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Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 56 | Systemic Mannitol-Induced Hyperosmolality Amplifies rAAV2-Mediated Striatal Transduction to a | ||
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Summary: on facilitation of transgene expression and vector distribution in the CNS. Systemic intraperitoneal... protein product and intra- parenchymal spread of an adenoviral vector can be facilitated by systemic... antibodies inhibit rAAV2-, but not rAAV5-mediated gene ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 57 | Brain Tissue Depth (mm) LightPowerDensity(mW/mm2 | ||
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Summary: and packaging The recombinant AAV vectors were serotyped with AAV5 coat proteins and packaged by the viral... A. Control of BLA glutamatergic projection neurons was achieved using an adeno-associated virus (AAV5) vector... ITC cells BLA CeA ... |
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Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 58 | This article was published in an Elsevier journal. The attached copy is furnished to the author for non-commercial research and | ||
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Summary: ., 2006; Sondhi et al., 2007). Thus, rAAV1, rAAV5, rAAV8, and rAAV10 have been shown to transduce more... ://www.elsevier.com/copyright #12;Author's personal copy Viral vectors for in vivo gene transfer in Parkinson's disease: Properties... in vivo gene transfer vectors that have been developed to a degree ... |
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Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 59 | Global and local fMRI signals driven by neurons defined optogenetically by type and wiring | ||
|
Summary: with the adeno-associated viral vector AAV5-CaMKIIa::ChR2(H134R)-EYFP todrive expressionofachannelrhodopsin(ChR2... observed with AAV5-CaMKIIa::ChR2- EYFP but not with saline injection (P , 0.001; asterisk, optical... Figure 2 | Nonlocal mapping of the causal role of cells defined by ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 60 | [23] Adeno-Associated Virus Vectors for Short Hairpin RNA Expression | ||
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Summary: of AAV-5 to -8 between 1984 and 2002 (reviewed by Grimm and Kay, 2003). The most significant expansion... , best yields are obtained with AAV serotype 8, followed by AAV-5, with both typically giving at least... [23] Adeno-Associated Virus Vectors for Short Hairpin RNA Expression By Dirk ... |
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|
Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 61 | MOLECULAR THERAPY Vol. 4, No. 4, October 2001 Copyright The American Society of Gene Therapy | ||
|
Summary: ] to facilitate splicing. In the strategy described by Sun, et al. [8], trans-splicing vectors were generated... , R. W., Zabner, J., and Chiorini, J. A. (2001). Adeno- associated virus serotype 4 (aav4) and aav5... Expanding AAV Packaging Capacity with Trans-splicing or Overlapping ... |
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|
Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 62 | BioMed Central Page 1 of 9 | ||
|
Summary: : Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors. Neurore- port 2000, 11... Open AccessResearch Comparative analysis of HIV-1-based lentiviral vectors bearing lyssavirus... vectors represents an appealing strategy for the treatment of nerve injury and ... |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 63 | RNAi based gene therapy for Spinocerebellar ataxia-7 HHMI Med-Into-Grad Proposal | ||
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Summary: , Chiorini, JA and Davidson, BL. Transduction of murine cerebellar neurons with recombinant FIV and AAV5... of viral vector based RNA interference (RNAi) for the mutated allele, is attractive as a potential... treatment for SCA7. The retina is an ideal target for viral vector mediated gene transfer, because |
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|
Source: Gleeson, Joseph G. - Department of Neurosciences, University of California at San Diego |
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Collection: Biology and Medicine |
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| 64 | RNA knockdown as a potential therapeutic strategy in Parkinson's disease | ||
|
Summary: to the midbrain, but to date, rAAV1 and rAAV5 appear to provide the widest area of transduction, while gene... ) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5- mediated, gene transfer in the brain. J... RNAs delivered by viral vectors. RNA interference can ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 65 | MOLECULAR THERAPY Vol. 5, No. 1, January 2002 Copyright The American Society of Gene Therapy | ||
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Summary: FIV and AAV5 vectors. Neuroreport 11: 26692673. 27. Choi-Lundberg, D. L., et al. (1998). Behavioral... delivery to the central nervous system (CNS) has been facilitated by the development of new viral vectors... using adeno-associated virus, a vector with low ... |
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|
Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 66 | LETTER doi:10.1038/nature10194 Excitatory transmission from the amygdala to | ||
|
Summary: -Camk2aEYFP and AAV-Camk2aNpHR3.0EYFP were packaged as AAV5 by the University of North Carolina vector... recombinant AAV vectors were serotyped with AAV5 coat proteins and packaged by the UNC vector core facilities... ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 67 | Characterization of the Relationship of AAV Capsid Domain Swapping to Liver | ||
|
Summary: to AAV-5. Virology 353: 6882. 11. Nakai, H, Fuess, S, Storm, TA, Muramatsu, S, Nara, Y and Kay, MA (2005... Recombinant adeno-associated virus (AAV) vectors show promise for use in gene therapy. For liver-targeted gene... transfer in animals, AAV vectors pseudotyped with the AAV serotype 8 (AAV8) capsid ... |
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|
Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 68 | Optogenetics in Neural Systems Ofer Yizhar,1 Lief E. Fenno,1 Thomas J. Davidson,1 Murtaza Mogri,1 and Karl Deisseroth1,2,3,4,* | ||
|
Summary: /5, referred to simply as AAV2 or AAV5 here). AAV2 differs from AAV5 in the degree of viral spread, in both... rodents (Paterna et al., 2004) and primates (Mar- kakis et al., 2010). A microliter-scale volume of AAV5... Elsevier Inc. Neuron Primer #12;Samulski, 1998; ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 69 | original article The American Society of Gene & Cell Therapy Molecular Therapy 1 | ||
|
Summary: ). All of the vectors contained AAV5 serotype capsids. These had been shown by us and others14... . MAterIAls And MetHods rAAV vectors. All vectors have been packaged in AAV5 capsid and puri- fied... as the PLD2 rAAV vector. ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 70 | W W W. N A T U R E . C O M / N A T U R E | 1 SUPPLEMENTARYINFORMATION doi:10.1038/nature10360 | ||
|
Summary: of a 40 µm coronal brain slice from a PV::Cre mouse bilaterally injected with Cre-dependent AAV5-EF1-DIO... injected with AAV5-CaMKII-SSFO-EYFP. Activation with 470 nm light (blue bar) triggered depolarization... /E162T) and AAV5-EF1-DIO-ChR2(H134R). (c) Voltage ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 71 | Vectors of Gene Therapy KATHERINE PARKER PONDER, M.D. | ||
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Summary: facilitates the preparation of very high titers of adenoviral vectors. Adenoviral Genes and Sequences Required... CHAPTER 4 Vectors of Gene Therapy KATHERINE PARKER PONDER, M.D. INTRODUCTION Currently, gene... to a cellular RNA can function in a similar fashion. Facilitating the transfer of genetic ... |
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|
Source: Ponder, Katherine P. - Departments of Medicine & Biochemistry and Molecular Biophysics, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 72 | JOURNAL OF VIROLOGY, Mar. 2004, p. 31103122 Vol. 78, No. 6 0022-538X/04/$08.00 0 DOI: 10.1128/JVI.78.6.31103122.2004 | ||
|
Summary: Uncoating of Vector Genomes Is the Key to Efficient Liver Transduction with Pseudotyped Adeno... -Associated Virus Vectors Clare E. Thomas, Theresa A. Storm, Zan Huang, and Mark A. Kay* Departments of Pediatrics... (AAV2) vectors is ineffi- cient; less than 10% of hepatocytes are permissive for stable transduction |
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|
Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 73 | www.sciencemag.org/cgi/content/full/330/6011/1677/DC1 Supporting Online Material for | ||
|
Summary: ://www.stanford.edu/group/dlab/optogenetics/sequence_info.html. The recombinant AAV vectors were serotyped with AAV5 coat proteins and packaged by the viral vector core... Animals. Virus production As described previously (2, 3), Cre-inducible recombinant AAV vectors were based... -floxed ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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|
Collection: Biology and Medicine |
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| 74 | SUPPLEMENTARY INFORMATION 1www.nature.com/nature | ||
|
Summary: are available online at www.optogenetics.org. The recombinant AAV vectors were serotyped with AAV5 coat proteins... , efficacy and transduction region. a, AAV5-CaMKII::ChR2-EYFP: Costaining for the excitatory marker Ca... .1038/nature09108 SUPPLEMENTARY INFORMATION Supplementary Figure 5 ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 75 | Adv Biochem Engin/Biotechnol (2005) 99: 1x DOI 10.1007/10_006 | ||
|
Summary: receptors [9395]. It has also been shown that AAV3 also binds heparan sulfate, AAV4 and AAV5 bind... to specific sialic acid linkages [96], and AAV5 binds to the PDGF receptor [97], whereas the receptors... distinct gene delivery properties. For example, in the brain AAV2 se- lectively transduces neurons, ... |
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|
Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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|
Collection: Materials Science ; Chemistry |
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| 76 | original article The American Society of Gene & Cell Therapy Molecular Therapy 1 | ||
|
Summary: si-312 si-312 AAV5 em pty R atsyn 100 80 60 40 20 0 b Figure 5 Quantitative estimation... terminal repeats and were packaged in AAV5 capsids that were purified as described previously.4,23 The GFP... in addition to the shRNA cassette driven by an H1 promoter. Empty ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 77 | Heparin binding induces conformational changes in Adeno-associated virus Hazel C. Levy a | ||
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Summary: used to determine the structures of several AAV ser- otypes, including AAV1, AAV2, AAV4, AAV5, AAV7... ), with the AAV5 structure (Walters et al., 2004) serving as the start- ing search model for the procedure. A low... and enter host cells is necessary to develop efficacious, targeted ... |
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|
Source: Baker, Timothy S. - Department of Chemistry and Biochemistry, University of California at San Diego |
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Collection: Biology and Medicine |
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| 78 | Current Gene Therapy, 2007, 7, 347-360 347 1566-5232/07 $50.00+.00 2007 Bentham Science Publishers Ltd. | ||
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Summary: unpublished obser- vations). Finally, we have shown that acute re-administration of rAAV5 vectors, which... we re-administer a different serotype, rAAV5 expressing GFP in the second injection site, no enhanced... neutral- izing antibodies were observed and these antibodies were specific ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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|
Collection: Biology and Medicine |
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| 79 | JOURNAL OF VIROLOGY, Apr. 2004, p. 41654175 Vol. 78, No. 8 0022-538X/04/$08.00 0 DOI: 10.1128/JVI.78.8.41654175.2004 | ||
|
Summary: strand genome conversion of AAV-2 and AAV-5 is not rate limiting following apical infection of polarized... . Targeted Correction of Single-Base-Pair Mutations with Adeno-Associated Virus Vectors under Nonselective... 28 July 2003/Accepted 2 January 2004 Recombinant adeno-associated virus (rAAV) vectors ... |
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|
Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa |
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Collection: Biology and Medicine |
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| 80 | Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain | ||
|
Summary: AAV2 vectors packaged in AAV5 capsids) was purified by iodixanol step gradients and Sepharose Q column... neurons and glia in the primate midbrain Pseudotyped rAAV2/5 vectors (rAAV2 vectors packaged in an AAV5... proteins for attachment and ... |
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|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 81 | Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain | ||
|
Summary: AAV2 vectors packaged in AAV5 capsids) was purified by iodixanol step gradients and Sepharose Q column... neurons and glia in the primate midbrain Pseudotyped rAAV2/5 vectors (rAAV2 vectors packaged in an AAV5... proteins for attachment and ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 82 | HUMAN GENE THERAPY 18:367378 (April 2007) Mary Ann Liebert, Inc. | ||
|
Summary: facilitated novel AAV vector purification via a monomeric avidin column (Arnold et al., 2006). The yields... -titer, high-purity recombinant vectors. However, numerous purification protocols can involve challeng- ing... at infectious particle yields exceeding 90%. Furthermore, injection of IMAC-purified ... |
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|
Source: Long, Jeffrey R.- Department of Chemistry, University of California at Berkeley |
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Collection: Materials Science ; Chemistry |
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| 83 | Imaging living central neurones using viral gene transfer A.G. Teschemachera | ||
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Summary: for fluorescent proteins into relevant cellular targets, molecular tools are required. Viral vectors are one... ; Viral vectors; Adenovirus; Lentivirus Contents 1. Introduction... ;3. Viral vectors for imaging applications |
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|
Source: Bristol, University of - Department of Physiology and Pharmacology, Viral Gene Transfer Lab. |
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Collection: Biology and Medicine |
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| 84 | W W W. N A T U R E . C O M / N A T U R E | 1 SUPPLEMENTARYINFORMATION doi:10.1038/nature10194 | ||
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Summary: serotyped with AAV5 coat proteins and packaged using calcium phosphate precipitation methods by the UNC... purification, restriction digest, and sequencing to assure DNA fidelity, purified recombinant AAV vectors were... Vector Core facilities (University of North Carolina, Chapel Hill). The final viral ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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| 85 | Recombinant Adeno-associated Viral Vectors as Therapeutic Agents to Treat Neurological Disorders | ||
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Summary: by lentiviral vectors in the brain has been shown to decrease Ah load in AD mice [90]. rAAV5 encoding neprilysin... I). Another study using rAAV5 to deliver an shRNA in the aggressive R6/1 transgenic HD mouse line... rAAV5 encoding an shRNA ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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Collection: Biology and Medicine |
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| 86 | original article The American Society of Gene & Cell Therapy Molecular Therapy vol. 18 no. 5, 873880 may 2010 873 | ||
|
Summary: was pseudotyped with the AAV5 capsid proteins and produced at the University of Florida Vector Core. The virus... phenotype. This functional analysis also facilitated the evaluation of various thera- peutic approaches.4... (AAV) vectors has resulted in sus- tained increased NAGLU ... |
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|
Source: Orrock, John - Department of Zoology, University of Wisconsin at Madison |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 87 | Frontiers in Macromolecular Imaging | ||
|
Summary: antibodies directed against AAV1, AAV2, AAV5, AAV6, and AAV8, which represent the range of sequence homology... Neutralization escape viral gene delivery vector engineering utilizing structurally mapped antigenic eptiopes... with the latest FEI instrument for Structural Biology (Titan Krios), the EPU package ... |
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|
Source: McQuade, D. Tyler - Department of Chemistry and Biochemistry, Florida State University |
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Collection: Chemistry |
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| 88 | BioMed Central Page 1 of 12 | ||
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Summary: Pseudotyped AAV vectors were generated by packaging AAV2-based recombinant genomes in AAV1, AAV2 or AAV5... for AAV1 and pLT- RC03 for AAV5) and the relevant pAAV2 vector plasmid. ssAAV vectors were produced... CD34+ progenitors, using lentiviral ... |
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|
Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique |
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|
Collection: Physics |
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| 89 | Robust Systemic Transduction with AAV9 Vectors in Mice: Efficient Global Cardiac Gene Transfer Superior | ||
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Summary: Robust Systemic Transduction with AAV9 Vectors in Mice: Efficient Global Cardiac Gene Transfer... vector that overcomes many of the limitations of rAAV2 and transduces various tissues efficiently... and globally through systemic vector administration. AAV9 is a serotype newly isolated from human tissues |
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|
Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 90 | Correction: 21 May 2009 www.sciencemag.org/cgi/content/full/1168878/DC1 | ||
|
Summary: regulatory element (WPRE) to enhance expression. The recombinant AAV vectors were serotyped with AAV5 coat... -inducible recombinant AAV vectors (2-4), the DNA cassette carrying two pairs of incompatible lox sites (loxP and lox2722... of the pAAV2-MCS vector carrying the EF-1 promoter and ... |
|||
|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University; Vosshall, Leslie - L:aboratory of Neurogenetics and Behavior, Rockefeller University |
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Collection: Biology and Medicine |
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| 91 | COLE DOCTORALE : DES GNOMES AUX ORGANISMES UNIVERSIT D'VRY VAL D'ESSONNE | ||
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Summary: ........................................................................................................................... 2 2.2. Caractéristiques et production du vecteur AAV... ............................................................................. 5 2.3. Les différents sérotypes AAV |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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|
Collection: Mathematics |
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| 92 | Sustained Striatal Ciliary Neurotrophic Factor Expression Negatively Affects | ||
|
Summary: by recombinant adeno-associated viral vectors (rAAV2). Wild-type and R6/1 HD transgenic (R6/1) mice that received... administration of CNTF on cells in the striatum, a recombinant adeno-associated viral vector was engi- neered... to express a secretable form of CNTF and pack- aged into viral particles (rAAV2-CNTF). rAAV vectors ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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|
Collection: Biology and Medicine |
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| 93 | JOURNAL OF VIROLOGY, Oct. 2007, p. 1129011303 Vol. 81, No. 20 0022-538X/07/$08.00 0 doi:10.1128/JVI.00963-07 | ||
|
Summary: with a Modest Arm Length of 20 Base Pairs Are a Significant Target for Recombinant Adeno-Associated Virus Vector... shown that recombinant adeno-associated virus (rAAV) vector integrates preferen- tially in genes, near... with rAAV2 or rAAV8 vector. The results support our previous observations, but notably they have revealed |
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|
Source: Kay, Mark A. - Department of Genetics, Stanford University |
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|
Collection: Biology and Medicine |
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| 94 | Dynamics of Retrieval Strategies for Remote Memories | ||
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Summary: RI restriction sites. The recombinant AAV vectors were serotyped with AAV5 coat proteins and packaged... as the experimental mice associated with laser light delivery. For BLA optogenetic inhibition, 1.5 ml of AAV5 Ca... attached to the IFL using a connecting plastic sleeve. For ACC ... |
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|
Source: Contractor, Anis - Department of Physiology, Northwestern University; Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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|
Collection: Biology and Medicine |
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| 95 | This article was published in an Elsevier journal. The attached copy is furnished to the author for non-commercial research and | ||
|
Summary: AAV encoding parkin was produced using the same expression cassette but the vector was packaged using the AAV5... in rAAV2 (experiment 1) or rAAV5 (experiment 23) capsids. TR=terminal repeats (B) The sequence... /5 viruses the pDG plasmid was substituted for the pXYZ5 plasmid which ... |
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|
Source: Mandel, Ronald J. - Department of Neuroscience, University of Florida |
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|
Collection: Biology and Medicine |
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| 96 | JOURNAL OF VIROLOGY, Jan. 2005, p. 214224 Vol. 79, No. 1 0022-538X/05/$08.00 0 doi:10.1128/JVI.79.1.214224.2005 | ||
|
Summary: Transduction with Adeno-Associated Virus Serotype 8 Vectors in Mice Hiroyuki Nakai,1 * Sally Fuess,1 Theresa A... adeno-associated virus (rAAV) vectors can mediate long-term stable transduction in various target... tissues. However, with rAAV serotype 2 (rAAV2) vectors, liver transduction is confined to only a small |
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|
Source: Kay, Mark A. - Department of Genetics, Stanford University |
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|
Collection: Biology and Medicine |
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| 97 | LETTER doi:10.1038/nature09820 Amygdala circuitry mediating reversible and | ||
|
Summary: transduced with an adeno-associated virus serotype 5 (AAV5) carrying codon-optimized channelrhodopsin (ChR2... YFP plasmids were designed and constructed by standard methods and packaged as AAV5. Virus (0.5 ml... .AllviruseswerepackagedatUniversityofNorthCarolina (UNC)Vector Core. ... |
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|
Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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|
Collection: Biology and Medicine |
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| 98 | Fax +41 61 306 12 34 E-Mail karger@karger.ch | ||
|
Summary: and AAV5 vec- tors. Neuroreport 2000;11:26692673. 5 Haskell RE, Hughes SM, Chiorini JA, Alisky JM... ;28:216221 DOI: 10.1159/000091919 Cerebellar Neurons and Glial Cells Are Transducible by Lentiviral Vectors... . In vitro, primary cell cultures of rat cerebellar granule cells were infected with lentiviral ... |
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|
Source: Bongarzone, Ernesto R. - Department of Anatomy and Cell Biology, University of Illinois at Chicago |
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|
Collection: Biology and Medicine |
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| 99 | JOURNAL OF VIROLOGY, June 2010, p. 58805889 Vol. 84, No. 12 0022-538X/10/$12.00 doi:10.1128/JVI.02719-09 | ||
|
Summary: -associated virus (AAV) serotypes AAV1 to AAV3, AAV5, and AAV9; the Erythrovirus B19; and the newly discovered human... sequence (NCBI accession number DQ000495; start codon, nucleotide [nt] 3373), and cloned into a pUC vector... (Epoch Biolabs, Inc., Missouri City, TX). The vector was cut with EcoRV and ... |
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|
Source: Baker, Timothy S. - Department of Chemistry and Biochemistry, University of California at San Diego |
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|
Collection: Biology and Medicine |
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| 100 | ARTICLE doi:10.1038/nature09553 Genetic dissection of an amygdala | ||
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Summary: CEm CEm CEm h i j m n o PKC-::GluCl-iresCre Merge p q r PosteriorCE AAV 5 CMV hrGFP pA AAV 3STOP CEm... CEl 250 m l CTB injection AnteriorCE v ProjectionsiteInjectionsite AAV 5 EF1 ChR2YFP pA AAV 3 CEm CEl... Wildtype l CEl h m n o p PKC-+ PKC- CEI CEm Merge Cherry/TOPRO CEl CEl CEl CEl ... |
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Source: Deisseroth, Karl - Departments of Psychiatry and Behavioral Sciences & Bioengineering, Stanford University |
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Collection: Biology and Medicine |
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