| Sample search results for: a2 activates p38 |
| 1 | Structures of p38 Active Mutants Reveal Conformational Changes in L16 Loop that Induce | ||
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Summary: Data Bank32 with accession codes 2FST for p38D176A + F327L , 2FSO for p38D176A , 2FSL for p38D176A + F... Structures of p38 Active Mutants Reveal Conformational ... |
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Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem |
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Collection: Biotechnology ; Biology and Medicine |
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| 2 | *Department of Chemistry and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, USA Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA | ||
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Summary: increase in level and activation of p38 and its upstream activator mitogen-activated protein kinase kinase... precursor protein (APP)-transgenic mice exhibit aberrant b-amyloid (Ab) accumulation and higher p38 activity... ... |
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Source: Jiang, Wen - Department of Biological Sciences, Purdue University |
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Collection: Biology and Medicine |
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| 3 | Molecular Cell Direct Activation of TACE-Mediated Ectodomain | ||
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Summary: Molecular Cell Article Direct Activation of TACE-Mediated Ectodomain Shedding by p38 MAP Kinase... ectodomain shedding. Activation of TACE by p38 MAP kinase results in the release of TGF-a family ligands... of p38a MAP kinase ... |
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Source: Derynck, Rik - Cardiovascular Research Institute, University of California at San Francisco |
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Collection: Biology and Medicine |
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| 4 | p38 Mitogen-Activated Protein Kinase Controls Two Successive Steps During the Early | ||
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Summary: p38 Mitogen-Activated Protein Kinase Controls Two Successive Steps During the Early Mesodermal... . We previously found that the p38 mitogen activated kinase (p38MAPK) pathway controls the commitment... approaches, we ... |
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Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique |
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Collection: Physics |
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| 5 | Less than 15 years ago, researchers studying the metabolic responses to mating phermones by yeast discovered novel | ||
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Summary: or stress-activated protein kinases (JNK/SAPK), and the p38 family of kinases (Fig. 1). Each of the MAPK... specificity. The and isoforms of p38 are responsible for the activation of heat shock proteins (hsps) 25, 27... and the MAPK-activated ... |
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Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 6 | p38 MAPK Stimulates Estrogen-Mediated Transcription and Proliferation Through the Phosphorylation and Potentiation of the p160 Coactivator GRIP1 | ||
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Summary: of GRIP1 transcriptional activation. The C-terminus of GRIP1 was also demonstrated to contain a p38... , interaction between TR and GRIP1 is synergistically potentiated by activation of p38 MAPK (21). Thus, we... , we used dichlorodiphenyltrichloroethane (DDT), which ... |
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Source: McLachlan, John - Environmental Endocrinology Laboratory, Tulane University |
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Collection: Environmental Sciences and Ecology |
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| 7 | Active Mutants of the TCR-Mediated p38 Alternative Activation Site Show Changes in the Phosphorylation | ||
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Summary: Active Mutants of the TCR-Mediated p38 Alternative Activation Site Show Changes... -cells; signaling; alternative activation The p38 mitogen-activated protein kinase is commonly activated by dual... -cells, ... |
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Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem |
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Collection: Biotechnology ; Biology and Medicine |
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| 8 | In vitro Glycoxidized Low-Density Lipoproteins and Low-Density Lipoproteins Isolated from Type 2 Diabetic Patients Activate Platelets via p38 MAPK | ||
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Summary: Activation of p38 mitogen-activated protein kinase/cytosolic phospholipase A2 cascade in hydroperoxide... Diabetic Patients Activate Platelets via p38 MAPK Catherine Calzada, Laurent Coulon, Déborah ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 9 | Development/Plasticity/Repair Sciatic Nerve Ligation-Induced Proliferation of Spinal Cord | ||
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Summary: Astrocytes Is Mediated by Opioid Activation of p38 Mitogen-Activated Protein Kinase Mei Xu, Michael R... BNIpretreatment.ProliferationofculturedtypeIIastrocytesmayhavebeenstimulatedbymitogen-activatedprotein kinase (MAPK) activation by KOR because (1) U50,488 treatment increased ... |
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Source: Bruchas, Michael R. - Department of Anesthesiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 10 | Mechanism of AP-1-mediated gene expression by select organochlorines through the p38 MAPK pathway | ||
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Summary: activation of the p38 kinase cas- cade and AP-1. Introduction Activator protein-1 (AP-1) is a generic term... -mediated signaling (15). However, exceptions to these general concepts exist. For example, increased p38 activity has... ... |
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Source: McLachlan, John - Environmental Endocrinology Laboratory, Tulane University |
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Collection: Environmental Sciences and Ecology |
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| 11 | This is an un-copyedited author manuscript that was accepted for publication in Hypertension, copyright The American Heart Association. This may not be duplicated or reproduced, other than for personal use or within the "Fair Use of Copyrighted Materials" | ||
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Summary: , myogenic tone and the associated p38 and Hsp27 phosphorylation depend on RhoA/Rho kinase activation... study, in resistance arteries, we found that activation of p38 MAP kinase contributes to vascular smooth... activates ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 12 | Adenosine Receptor, Protein Kinase G, and p38 Mitogen-Activated Protein Kinase-Dependent Up-Regulation of | ||
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Summary: Adenosine Receptor, Protein Kinase G, and p38 Mitogen- Activated Protein Kinase-Dependent Up... GMP effects. NECA stimulation activates p38 mitogen-activated protein kinase (MAPK), whereas p38 MAPK... ... |
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Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 13 | Rewriting Game Theory Applied to Protein Signalling in MAPK Cascades | ||
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Summary: and differentiation whilst JNK and p38 are strongly activated by stress and inflammatory cytokines [30, 5]. Although... , the kinases are rapidly converted to the active state, as threonine is phosphorylated [26]. The p38 pathway... ) and MAPKKK1 (MEKK1) are the widely ... |
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Source: Vestergaard, René - School of Information Science, Japan Advanced Institute of Science and Technology |
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Collection: Mathematics ; Computer Technologies and Information Sciences |
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| 14 | Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression | ||
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Summary: to stimulation by the Th1 cytokine interleukin-12 (IL-12) show greatly reduced p38 MAPK activation compared... microglia with TNF-a and the P2X7 receptor agonist BzATP attenuates p38 MAPK activation, this is not true... the effects on ... |
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Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 15 | A transcriptional signaling pathway in the IFN system mediated by 2 -5 -oligoadenylate | ||
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Summary: (2 p5 A)2, which fails to activate RNase L. RNA was analyzed on a custom innate immune response c... , inhibition with SB203580 of p38, which is constituitively active in these cells, had no effect on MIC-1 NAG-1... pattern that stimulates OAS to ... |
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Source: Silverman, Robert H. - Department of Cancer Biology, Cleveland Clinic Lerner Research Institute |
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Collection: Biology and Medicine |
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| 16 | Lysophosphatidylcholine Activates p38 and p42/44 Mitogen-Activated Protein Kinases in Monocytic THP-1 | ||
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Summary: Lysophosphatidylcholine Activates p38 and p42/44 Mitogen-Activated Protein Kinases in Monocytic THP... -1 Cells, but Only p38 Activation Is Involved in Its Stimulated Chemotaxis Qing Jing, Sun-Mei Xin... phosphorylation and ... |
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Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences |
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Collection: Biology and Medicine |
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| 17 | MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, June 2004, p. 320344 Vol. 68, No. 2 1092-2172/04/$08.00 0 DOI: 10.1128/MMBR.68.2.320344.2004 | ||
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Summary: Rights Reserved. ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse... of vertebrate MAPKs to date are the ERK1/2, JNKs, and p38 kinases. MAPKs can be activated by a wide variety... of the ERK1/2 and ... |
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Source: Blenis, John - Department of Cell Biology, Harvard University |
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Collection: Biology and Medicine |
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| 18 | # 2008 The Authors Journal compilation # 2008 Blackwell Munksgaard | ||
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Summary: kinase C, protein kinase G and p38 mitogen- activated protein kinase receiving the greatest attention... : A3 adenosine receptor, interleukin-1b, p38 mitogen-activated protein kinase, protein kinase C... , suggesting that Caþþ - mediated signaling events downstream ... |
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Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 19 | Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, | ||
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Summary: growth regulative protein, PKC, and the activation of JNK and p38 MAP kinases. The changes... protein kinase (JNK/SAPK) and p38 mitogen-activated protein (MAP) kinases, as well as prolong the G2 cell... , activation of JNK and ... |
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Source: Kan, Lou-sing - Institute of Chemistry, Academia Sinica (Taiwan) |
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Collection: Chemistry |
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| 20 | Selective p38a MAPK Deletion in Serotonergic Neurons Produces Stress Resilience | ||
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Summary: understood. Using a conditional gene knockout approach, the a isoform of p38 mitogen-activated protein kinase... of mitogen-activated protein kinases (MAPK). Using pharmacological approaches, p38 MAPK (also called SAPK... that ... |
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Source: Bruchas, Michael R. - Department of Anesthesiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 21 | Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins | ||
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Summary: and require p38 MAPKK for full induction (Table 1). Reducing the products of either Y39E4A.2 or F26G1... response is distinct from that seen with a different stressor, the heavy metal cadmium. A p38 mitogen-activated... to mammalian cells because ... |
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Source: áik, Roman - Department of Pathology, University of California San Diego |
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Collection: Biology and Medicine |
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| 22 | JOURNAL OF CELLULAR PHYSIOLOGY 199:4756 (2004) Ceramide Induces Caspase-Dependent and -Independent | ||
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Summary: , caspase activation, and PARP or PKC-d degradation. SB202190, a specific inhibitor of p38 mitogen-activated... ; Martin- Blanco, 2000). Ceramide was shown to inhibit ERK activity but activate JNK and p38 MAPK in some... ), ... |
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Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences |
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Collection: Biology and Medicine |
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| 23 | J Physiol 586.18 (2008) pp 44654479 4465 Serotonin facilitates long-term depression induction | ||
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Summary: of serotonin on LTD was blocked by selective inhibitors of p38 mitogen-activated protein kinase (MAPK... synergistically activated p38 MAPK in PFC slices. The serotonin-facilitated LTD induction was prevented... on the same day and tissue was processed in parallel. ... |
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Source: Yan, Zhen - Department of Physiology and Biophysics, State University of New York at Buffalo |
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Collection: Biology and Medicine |
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| 24 | Proc. Natl. Acad. Sci. USA Vol. 92, pp. 10531-10534, November 1995 | ||
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Summary: ). In human cells, p38 kinase is activated by tyrosine and threonine phos- phorylation in response... -stimulated, or treated with arsenite [which increases p38 activity (19)] (Figs. 4 and 5). We studied Max phosphorylation... kinases, MKK3 and SEK1 (MKK4) (34, 35), ... |
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Source: Brent, Roger - Fred Hutchinson Cancer Research Center |
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Collection: Biology and Medicine |
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| 25 | regulation of transcription factor targets in muscle and heart of the hibernating bat, Myotis lucifugus | ||
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Summary: suggests an important role for the p38 mitogen-activated protein kinase (p38MAPK ) and selected downstream... and levels of the phosphorylated, active forms of p38MAPK , CREB, ATF-2 and Elk-1 in both skeletal muscle... and ... |
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Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 26 | Osmosensing by transporting epithelial cells is an intriguing way to regulate transepithelial transport, because it does not | ||
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Summary: that cytoplasmic phospholipase A2 (cPLA2) is activated by hypotonic shock, resulting in increase of arachidonic... . There was no significant change in transepithelial resistance with Gö6976 (data not shown). p38 mitogen activated protein... treatments. ... |
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Source: Marshall, William S. - Department of Biology, St. Francis Xavier University |
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Collection: Environmental Sciences and Ecology |
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| 27 | Kappa Opioid Receptor Activation of p38 MAPK Is GRK3-and Arrestin-dependent in Neurons and Astrocytes* | ||
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Summary: Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons... to be required for receptor desensitization, and the results suggest that p38 MAPK activation by KOR may require... phos- pho-p38 ... |
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Source: Bruchas, Michael R. - Department of Anesthesiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 28 | Research article 1544 TheJournalofClinicalInvestigation http://www.jci.org Volume 118 Number 4 April 2008 | ||
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Summary: and trafficking (12, 14, 15). Tonic activation p38 MAPK signal- ing pathways, without direct phosphorylation... of the transporter, controls basal surface SERT expression levels, whereas acute p38 MAPK activation induces... ... |
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Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 29 | Research article 886 TheJournalofClinicalInvestigation http://www.jci.org Volume 119 Number 4 April 2009 | ||
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Summary: mediators in the inflamma- tory response and atherosclerosis (14). Activation of p38 requires... to have important effects on advanced plaque progression. Recent work has shown that p38 MAPK is activated... is activated in plaques of both ... |
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Source: Tabas, Ira - Department of Physiology and Cellular Biophysics, Columbia University |
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Collection: Biology and Medicine |
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| 30 | p38 MAPK Activation Elevates Serotonin Transport Activity via a Trafficking-independent, Protein Phosphatase | ||
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Summary: p38 MAPK Activation Elevates Serotonin Transport Activity via a Trafficking-independent, Protein... downstream of adenosine receptor (AR) activation that is sensitive to p38 MAPK inhibitors. Here, we probe... this pathway in greater detail, demon- ... |
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Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 31 | Purinergic receptor modulation of BV-2 microglial cell activity: Potential involvement of p38 MAP kinase and CREB | ||
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Summary: Purinergic receptor modulation of BV-2 microglial cell activity: Potential involvement of p38 MAP... via a mechanism involving augmented activation of the p38/CREB pathway. D 2005 Elsevier B.V. All... , 2000; Watters et al., 2001) including the ... |
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Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 32 | Behavioral/Systems/Cognitive Stress-Induced p38 Mitogen-Activated Protein Kinase | ||
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Summary: Behavioral/Systems/Cognitive Stress-Induced p38 Mitogen-Activated Protein Kinase Activation... show that repeated swim stress caused activation of both -opioid receptor (KOR) and p38 mitogen-activated... between ... |
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Source: Bruchas, Michael R. - Department of Anesthesiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 33 | 2010NatureAmerica,Inc.Allrightsreserved. natURE mEthOdS | ADVANCEONLINEPUBLICATION | | ||
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Summary: 100 FLN A-1FLN A-2 R AN BP9-1 R AN BP9-2 P38 (M APK14) Luciferase Scram ble Knockdown(%) g +PMA si... ) at a higher molecular weight than p38 is indicated. (g) Activity of an AP-1 responsive luciferase reporter... to MUC12 knocked down both AP-1 ... |
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Source: Ideker, Trey G.- Department of Bioengineering, University of California at San Diego |
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Collection: Biotechnology ; Biology and Medicine |
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| 34 | Secretory Phospholipase A2 A Multifaceted Family of | ||
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Summary: by RhoA/Rho-associated kinase, RAS/MEK/ ERK, p38 mitogen-activated protein kinase (MAPK), and glycogen... synthase kinase-3 [34,35]. Group IIA sPLA2 , in turn, activates signaling pathways such as MEK/ERK1/2, p38... of sPLA2 activity. Currently, ... |
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Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
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Collection: Chemistry ; Biology and Medicine |
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| 35 | MOLECULAR AND CELLULAR BIOLOGY, Jan. 2003, p. 425436 Vol. 23, No. 2 0270-7306/03/$08.00 0 DOI: 10.1128/MCB.23.2.425436.2003 | ||
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Summary: -containing genes that may utilize AREs as a means of controlling cellular mRNA levels. The p38 mitogen-activated... activation by LPS exhibited p38-dependent transcript stabilization, including macrophage-specific colony... , the identification of the ... |
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Source: Williams, Bryan - Department of Genetics, Case Western Reserve University |
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Collection: Biology and Medicine |
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| 36 | MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/01/$04.00 0 DOI: 10.1128/MCB.21.20.69136926.2001 | ||
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Summary: and p38 Mitogen-Activated Protein Kinase Activation and Sensitization to Genotoxic Stress MORAN BENHAR... cells we were able to induce potentiation of JNK/p38 activation. Taken together, our findings suggest... have shown that JNK and/or ... |
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Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem |
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Collection: Biology and Medicine |
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| 37 | Distinct Ligand-dependent Roles for p38 MAPK in Priming and Activation of the Neutrophil NADPH Oxidase* | ||
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Summary: Distinct Ligand-dependent Roles for p38 MAPK in Priming and Activation of the Neutrophil NADPH... a subsequent oxidase-acti- vating stimulus. The relative role of p38 MAPK in the priming and activation... contributions of p38 ... |
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Source: Massachusetts Institute of Technology (MIT), Cell Decision Process Center |
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Collection: Biology and Medicine |
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| 38 | Current Biology, Vol. 13, 4752, January 8, 2003, 2003 Elsevier Science Ltd. All rights reserved. PII S0960-9822(02)01396-9 Caenorhabditis elegans Innate Immune Response | ||
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Summary: LPS [68]. One consequence of p38 activation in mammalian cells is programmed cell death (PCD). In C... of activates p38 or that Salmonella or E. coli LPS mutants fail to activate p38 have proved ... |
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Source: Ausubel, Frederick M. - Department of Genetics, Harvard University |
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Collection: Biology and Medicine |
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| 39 | CMLS, Cell. Mol. Life Sci. 55 (1999) 12301254 1420-682X/99/101230-25 $ 1.50+0.20/0 | ||
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Summary: to modify thethreonine kinase, which activates MEK (MAPK/ERK activity of SAPK and p38, and explores the down... ); p38; mitogen activated protein kinase (MAPK); apoptosis. The components The stress-activated protein... ], SAPK3 ... |
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Source: Woodgett, Jim - Ontario Cancer Institute, University of Toronto |
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Collection: Biology and Medicine |
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| 40 | TGF-b and TNF-a : antagonistic cytokines controlling type I collagen gene expression Franck VERRECCHIA and Alain MAUVIEL* | ||
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Summary: articular chondrocytes, TGF-b induces activation of ERK1/2, but not p38 or JNK MAP kinases [42]. Furthermore... ] and its activator, which have been shown to be important for TGF-b signaling through p38 MAP kinase... the up-regulatory effect of TGF-b on ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 41 | Carcinogenesis vol.30 no.1 pp.106113, 2009 doi:10.1093/carcin/bgn213 | ||
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Summary: September 12, 2008 Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated... dichlorodiphenyltrichloro- ethane (DDT) stimulates activator protein-1 activity through the p38 ... |
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Source: McLachlan, John - Environmental Endocrinology Laboratory, Tulane University |
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Collection: Environmental Sciences and Ecology |
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| 42 | Multidomain Synthetic Peptide B2A2 Synergistically Enhances BMP-2 Xinhua Lin,1 | ||
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Summary: designated B2A2 synergizes the activity of BMP-2. B2A2 interacts with BMP receptor isoforms, potentiating... the action of BMP-2 in activating alkaline phosphatase and triggering Smad and MAPK signaling. B2A2's design... and ... |
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Source: Brookhaven National Laboratory, Environmental Chemistry Division, Department of Applied Science |
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Collection: Environmental Sciences and Ecology |
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| 43 | PrtT-Regulated Proteins Secreted by Aspergillus fumigatus Activate MAPK Signaling in Exposed A549 | ||
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Summary: . Interestingly, DPrtT-derived CF did not induce ERK1/2 or JNK phosphorylation and only partially activated p38... blocked CF-induced A549 cell peeling, whereas inhibition of p38 kinase activity did not (Fig. 3A). Western... CF, unlike Figure 2. Phosphorylation of ... |
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Source: Shamir, Ron - School of Computer Science, Tel Aviv University |
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Collection: Computer Technologies and Information Sciences |
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| 44 | LDL from obese patients with metabolic syndrome show increased lipid peroxidation and activate platelets | ||
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Summary: ) Activation of p38 mitogen-activated protein kinase/cytosolic phospholipase A2 cascade in hydroperoxide... or antiphospho-p38 MAPK or anti-phospho-cytosolic phospholipase A2 (cPLA2) ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 45 | Serine 727 Phosphorylation and Activation of Cytosolic Phospholipase A2 by MNK1-related Protein Kinases* | ||
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Summary: is activated by p38-2a/2b in platelets. We therefore examined whether MNK1, MSK1, MAPKAP-K2, and PRAK1 could... A2 (cPLA2) is phosphorylated on Ser-505 by p38 protein kinase and on Ser-727 by an unknown ... |
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Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
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Collection: Chemistry ; Biology and Medicine |
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| 46 | -Arrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK Activation* | ||
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Summary: Enhancement of p38 MAPK Activation* Received for publication, July 19, 2002, and in revised form, September 16... -mediated activation of both p38 MAPK and ERK, and the suppression of -arrestin2 expression blocked... the activation of two kinases. ... |
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Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences |
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Collection: Biology and Medicine |
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| 47 | THE ROLE OF MAPKs IN ADIPOCYTE DIFFERENTIATION AND OBESITY | ||
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Summary: . The signalling from the membrane leading to activation of the p38 and JNK pathways is much less precisely defined... such as SB203580 to inhibit p38 activation. Engelman et al. were the first to describe a positive role for p... ), a ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 48 | Cellular Regulation of Cytosolic Group IV Phospholipase A2 by Phosphatidylinositol Bisphosphate Levels1 | ||
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Summary: 2, lysophospholipase, and transacylase activities of human cytosolic phospholipase A2. Biochim... mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin... of intracellular Ca2 response required for ... |
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Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego |
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Collection: Biology and Medicine |
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| 49 | Introduction Owing to their high consumption of oxygen and enrichment of | ||
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Summary: (Huot et al., 1998). In endothelial cells, H2O2 also causes activation of the p38 MAPK... 38 mitogen-activated protein kinase (MAPK), and that SB203580, a specific inhibitor of p38 MAPK... . These results suggest that H2O2 alters astrocyte ... |
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Source: Lee, James - Biological Engineering Department, University of Missouri-Columbia |
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Collection: Biology and Medicine |
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| 50 | p38 Mitogen-Activated Protein Kinase Is Critical for Synergistic Induction of the FSH Gene by | ||
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Summary: p38 Mitogen-Activated Protein Kinase Is Critical for Synergistic Induction of the FSH Gene... - tivity, which is activated by GnRH, and activin co- treatment augments p38 activation by GnRH. Both... ). In particular, ... |
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Source: Mellon, Pamela L. - Department of Reproductive Medicine, University of California at San Diego |
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Collection: Biology and Medicine |
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| 51 | p38 Mitogen-Activated Protein Kinase Is Critical for Synergistic Induction of the FSH Gene by | ||
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Summary: p38 Mitogen-Activated Protein Kinase Is Critical for Synergistic Induction of the FSH Gene... - tivity, which is activated by GnRH, and activin co- treatment augments p38 activation by GnRH. Both... ). In particular, ... |
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Source: Coss, Djurdjica - Department of Reproductive Medicine, University of California at San Diego |
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Collection: Biology and Medicine |
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| 52 | Rapid Stimulation of Presynaptic Serotonin Transport by A3 Adenosine Receptors | ||
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Summary: mediated by multiple Ser/Thr kinases, in- cluding protein kinases C and G (PKC and PKG) and p38 mitogen-activated... adenosine receptors (A3AR) stimulates SERT activity via both PKG and p38 MAPK (Zhu et al., 2004a). Whether A... (Carneiro and Blakely, 2006). In ... |
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Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 53 | Regulation of ES Cell Lineage Commitment by Mitogen Activated Protein Kinases | ||
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Summary: words: Mitogen Activated Protein Kinases; embryonic stem cells commitment; JNK pathway; p38MAPK pathway... to p38MAPK in undifferentiated ES cells, p38MAPK activation is involved in the early apoptosis observed... is ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 54 | THEJOURNALOFCELLBIOLOGY The Rockefeller University Press $8.00 | ||
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Summary: A scavenger re- ceptor (SRA). As evidence, FC loading by non-SRA M mechanisms activates p38 and CHOP... found that FC loading of macrophages activates the p38 MAPK and c-Jun NH2-terminal kinase (JNK) pathways... atherosclerotic lesions. Results ... |
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Source: Tabas, Ira - Department of Physiology and Cellular Biophysics, Columbia University |
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Collection: Biology and Medicine |
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| 55 | ORIGINAL ARTICLE Cisplatin induces PKB/Akt activation and p38MAPK | ||
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Summary: ORIGINAL ARTICLE Cisplatin induces PKB/Akt activation and p38MAPK phosphorylation of the EGF... studies have documented that Cisplatin triggers the activation of the Jun-N-terminal kinase (JNK) and p38... ., 1996; Benhar et al., 2001; Deschesnes et al., 2001). ... |
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Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem |
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Collection: Biology and Medicine |
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| 56 | Osmotic Stimulation of the Na+ Exchanger NHE1: Relationship to the Activation of | ||
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Summary: and dependence on osmolarity of Erk and p38 MAPK activation were found to be similar to that of NHE stimulation... the osmotic activation of Erk and p38 MAPK, respectively, it did not prevent the associated stimulation of NHE... 38 MAPK and SAPK. ... |
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Source: Woodgett, Jim - Ontario Cancer Institute, University of Toronto |
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Collection: Biology and Medicine |
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| 57 | MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA | ||
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Summary: -induced, but not arsenite-induced SGs. Exclusion of TTP from SGs depends on activation of p38-MAPK TTP is phosphorylated... by the stress-activated kinases p38- MAPK and MK2. Because arsenite activates the ... |
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Source: Blackwell, Keith - Harvard University |
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Collection: Biology and Medicine |
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| 58 | Phosphorylation of Cytosolic Group IV Phospholipase A2 Is Necessary but Not Sufficient for Arachidonic Acid | ||
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Summary: -0601 Received November 24, 1999 Activation of the cytosolic Group IV phospholipase A2 (cPLA2) by agonists has... from its phospholipid storage sites is regulated by the activation of phospholipase A2s (PLA2) (1... Phosphorylation of Cytosolic Group IV Phospholipase ... |
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Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego |
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Collection: Biology and Medicine |
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| 59 | MOLECULAR AND CELLULAR BIOLOGY, Oct. 2005, p. 85538566 Vol. 25, No. 19 0270-7306/05/$08.00 0 doi:10.1128/MCB.25.19.85538566.2005 | ||
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Summary: MEF cells, together with ERK5 and MEK5, the upstream activator for ERK5 (Fig. 6B). The p38 MAPK has... to expression of p38 and MKK6(E), an activated form of MKK6. We found that transfection of either ERK5 or MEK5(D... was transfected into erk5 / MEF cells with ERK5 ... |
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Source: Winoto, Astar - Department of Molecular and Cell Biology, University of California at Berkeley |
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Collection: Biology and Medicine |
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| 60 | Annu. Rev. Pharmacol. Toxicol. 1999. 39:17589 Copyright c 1999 by Annual Reviews. All rights reserved | ||
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Summary: , Watson SP, et al. 1996. p38 mitogen-activated protein kinase phos- phorylates cytosolic phospholipase A2... collection of signal-activated phospholipases are the phos- pholipase A2s. These enzymes hydrolyze the sn-2... ... |
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Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego |
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Collection: Biology and Medicine |
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| 61 | Mining Activity Clusters From Low-level Event Logs | ||
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Summary: the initial clusters 1, 3, and 6, so the initial cluster 1 would be the first occurrence of activity "A1A2A3... the realm of their high-level tasks, #12;4 A B C D A B C D a1 a2 a3 b5 b4 b6 c7 c8 c9 c8 d10 d11 d12 process... lastname p38 Brian 434 ... |
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Source: Aalst, W.M.P.van der - Wiskunde en Informatica, Technische Universiteit Eindhoven; van der Aalst, Wil - Wiskunde en Informatica, Technische Universiteit Eindhoven |
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Collection: Computer Technologies and Information Sciences |
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| 62 | New Insights into the Catalytic Activation of the MAPK Phosphatase PAC-1 Induced by its Substrate MAPK | ||
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Summary: that results in catalytic activation of the phosphatase. p38a also interacts with but does not activate PAC-1... , PAC-1 forms a stable complex with p38a, but it does not exhibit any catalytic activation by ... |
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Source: Zhou, Ming-Ming - Department of Structural and Chemical Biology, Mount Sinai School of Medicine |
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Collection: Biotechnology ; Biology and Medicine |
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| 63 | Molecular Cell, Vol. 8, 971982, November, 2001, Copyright 2001 by Cell Press Cytokine Stimulation of Energy Expenditure | ||
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Summary: of Energy Expenditure through p38 MAP Kinase Activation of PPAR Coactivator-1 cers, and heart failure... and chronic infection. While cytokines such as stress activated kinases p38 MAPK and JNK (Davis, IL-1 , IL-1... suggest a role for ... |
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Source: Mootha, Vamsi K. - Department of Systems Biology, Harvard University |
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Collection: Biology and Medicine |
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| 64 | Molecular and Cellular Biochemistry 209: 2937, 2000. 2000 Kluwer Academic Publishers. Printed in the Netherlands. | ||
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Summary: of the active phosphorylated form of p38 increased within 20 min as an early response to freezing in liver... and kidney but rose later (after 12 h) in heart. Both JNK and p38 were activated during thawing in liver... /thaw in frog brain was a transient elevation of ... |
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Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 65 | Immunity, Vol. 23, 319329, September, 2005, Copyright 2005 by Elsevier Inc. DOI 10.1016/j.immuni.2005.08.010 Signaling Pathways and Genes that Inhibit | ||
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Summary: an apoptotic re- sponse due to inhibition of p38 MAP kinase activation by the bacterial-produced lethal toxin... (LT), whose lethal factor (LF) catalytic subunit prevents p38 activation by cleav- age of the upstream... mediating the survival ... |
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Source: Hasty, Jeff - Department of Bioengineering, University of California at San Diego |
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Collection: Engineering |
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| 66 | Electro c o c t o o t e E e t E tor or ot o l r el l el rt o oll | ||
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Summary: #12; ol e Li ting procedure instantiateEmergencyProcess() var a1:Activity, a2:Activity, d1:Deferred... Choice ...; begin a1 := Create(Activity); [a1].name := [`HelicopterDelivery']; [a1].state := [#waiting]; a2... := ... |
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Source: Gogolla, Martin - Fachbereich 3 - Mathematik und Informatik, Universität Bremen |
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Collection: Computer Technologies and Information Sciences |
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| 67 | Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance | ||
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Summary: resistance through the modulation of PMK-1 activity. The regulation of p38 and JNK-like MAPK pathways... activators of p38 MAPK (1421). Genetic analysis in mice suggests nonredundant distinct roles for MKK4... and MKK7 in JNK activation in ... |
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Source: Ausubel, Frederick M. - Department of Genetics, Harvard University |
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Collection: Biology and Medicine |
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| 68 | Biochem. J. (2009) 421, 201210 (Printed in Great Britain) doi:10.1042/BJ20090356 201 NAD(P)H oxidase-mediated reactive oxygen species production alters | ||
|
Summary: then stimulated phosphorylation of p38 MAPK (mitogen-activated protein kinase) and ERK1/2 (extracellular... -signal-regulated kinase 1/2 (ERK1/2), F-actin, oxidative stress, p38 mitogen-activated protein kinase (MAPK). INTRODUCTION... - induced ROS production ... |
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|
Source: Lee, James - Biological Engineering Department, University of Missouri-Columbia |
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Collection: Biology and Medicine |
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| 69 | Analysis of signal transduction pathways during anoxia exposure in a marine snail: A role for p38 MAP kinase and downstream signaling cascades | ||
|
Summary: or the phosphorylation status of any key components. The content of active phospho-p38 MAPK was 2-fold higher... . Activation of these factors via p38 MAPK may be vital to the reorganization of metabolic responses to anoxia... ) family, ii) the ... |
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|
Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 70 | Biochem. J. (2006) 399, 427434 (Printed in Great Britain) doi:10.1042/BJ20061077 427 TAK1-binding protein 1 is a pseudophosphatase | ||
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Summary: pathways, in- cluding those that activate the MAPKs (mitogen-activated protein kinases), termed p38 MAPK... , which could underlie, at least in part, the feedback control of TAK1 activity by p38 MAPK [5]. We thank... . (2002) MAPKK-independent ... |
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|
Source: van Aalten, Daan - Division of Biological Chemistry and Molecular Microbiology, University of Dundee |
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Collection: Biology and Medicine |
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| 71 | Pour obtenir le grade de DOCTEUR DE L'UNIVERSIT DE GRENOBLE | ||
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Summary: ................................................................. 26 1.4.4.2. Régulation de la voie d'activation de p38... ).................................................................... 28 Figure 21 : Représentation schématique des voies d'activation des cascades de signalisation de ... |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 72 | *Corresponding author: Bart STAELS, INSERM UMR 1011, Universit Lille Nord de France, Institut Pasteur de Lille, 1 rue du Pr Calmette, BP245, 59019 Lille -France. Tel. +33.3.20.877.388 -Fax | ||
|
Summary: the ERK module is principally activated through the Ras/Raf pathway, the JNK and p38 modules are activated... heart functions by increasing fatty acid uptake and oxidation [65]. The p38 MAPK pathway is activated... PPAR, PTMs and cardiac ... |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 73 | Toxicology Letters 155 (2005) 227238 Xenobiotic-induced TNF-expression and apoptosis | ||
|
Summary: metabolites stimulate activator protein-1 (AP-1)-mediated gene expression through the p38 mitogen-activated... protein kinase (MAPK) cascade. Here, we determined that DDT-induced p38 activity produces a novel... -PCR and reporter gene assays. ... |
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|
Source: McLachlan, John - Environmental Endocrinology Laboratory, Tulane University |
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Collection: Environmental Sciences and Ecology |
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| 74 | Prostaglandins & other Lipid Mediators 78 (2005) 5566 Group IV cytosolic phospholipase A2 mediates | ||
|
Summary: in combination with platelet-derived growth factor leads to the activation of ERK and p38 MAPK, which in turn... ]. In H9c2 cells, p38 MAPK and c-Jun NH2- terminal kinase were activated by 200 M H2O2 exposure [6... to activate ... |
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|
Source: Dennis, Edward A. - Department of Chemistry and Biochemistry, University of California at San Diego |
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|
Collection: Biology and Medicine |
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| 75 | Specific SKN-1/Nrf Stress Responses to Perturbations in Translation Elongation and Proteasome Activity | ||
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Summary: that cooperate with SKN-1 but do not influence its nuclear accumulation. The evolutionarily conserved p38 mitogen-activated... by Western blotting for the dually phosphorylated, active form of p38 kinase [29,30]. We observed that both... exposed to TEF RNAi or CHX ... |
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|
Source: Blackwell, Keith - Harvard University |
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Collection: Biology and Medicine |
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| 76 | Nutrient-Gene Expression Flavonoid Phytochemicals Regulate Activator Protein-1 Signal Transduction | ||
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Summary: transformation specific oncoprotein superfamily, is activated by ERK1/2, JNK1/2 and p38 (42,45,46). Additionally... by ERK 1/2 and p38 (46,47). CHOP/Gadd153, a mem- ber of the C/EBP family, is activated primarily by p38... ... |
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|
Source: McLachlan, John - Environmental Endocrinology Laboratory, Tulane University |
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Collection: Environmental Sciences and Ecology |
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| 77 | Biochem. J. (1999) 344, 359366 (Printed in Great Britain) 359 Stress stimuli increase calcium-induced arachidonic acid release through | ||
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Summary: used: cPLA2, cytosolic phospholipase A2 ; ERK, extracellular signal-regulated kinase; MAPK, mitogen-activated... a\2b activities [17,27]. Pre- treatment with H # O # (2 mM) resulted in an increase in arachidonic... increase the intrinsic lipase ... |
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|
Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
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|
Collection: Chemistry ; Biology and Medicine |
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| 78 | CELLULAR & MOLECULAR BIOLOGY LETTERS Volume 12 (2007) pp 621 -632 | ||
|
Summary: calcium-dependent phospholipase A2; DTNB 5,5'-dithio-bis(2-nitrobenzoic acid); MAPK mitogen-activated... phospholipase A2 activation in arachidonic acid metabolism in human eosinophils. J. Immunol. 167 (2001) 461... PHOSPHOLIPASE ... |
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|
Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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|
Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 79 | Minocycline exerts inhibitory effects on multiple mitogen-activated protein kinases and IjBa degradation | ||
|
Summary: minocycline effects on activation of p38, c-Jun-N-terminal activated protein kinase (JNK) 1... be mediated via inhibition of microglial p38 MAPK activation. In the present study, we explored whether... -Jun-N-terminal ... |
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|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 80 | Cell Host & Microbe Antifungal Innate Immunity in C. elegans | ||
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Summary: converge downstream of nipi-3 to activate a conserved p38 MAPK signaling pathway (Pujol et al., 2008a... of tir-1 and the pmk-1/ p38 pathway for the control of nlp-29. We then placed the activated gpa-12... . elegans is analogous to the pathway regulating ... |
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|
Source: Ewbank, Jonathan - Centre d'Immunologie de Marseille-Luminy |
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Collection: Biology and Medicine |
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| 81 | The Role of p38 MAPK in Rhinovirus-Induced Monocyte Chemoattractant Protein-1 Production by Monocytic-Lineage | ||
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Summary: 16 (HRV16). Indeed, we have found p38 MAPK activation in human alveolar macrophages within 15 min... of exposure to HRV16, and this activation lasts up to 1 h. The targets of p38 MAPK activation include... transcriptional ... |
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|
Source: Bertics, Paul J. - Molecular and Cellular Pharmacology Training Program & Department of Biomolecular Chemistry, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 82 | of May 17, 2010 This information is current as | ||
|
Summary: phospholipases A2 (sPLA2s) are overexpressed in inflammatory lung diseases and cancer and they activate... -type receptor induces phosphorylation of the MAPKs p38 and ERK1/2 whose activity mediates several cellular... promoted by adenosine in sPLA2- ... |
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|
Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
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|
Collection: Chemistry ; Biology and Medicine |
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| 83 | TGF--induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing | ||
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Summary: of numerous TGF--regulated genes, including plasminogen activator inhibitor 1 (PAI-1) [44], JunB [45], COL1A2... suggest that TGF--activated p38 phosphorylation may be implicated in COL1A1 gene expression in dermal... the expression of ... |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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|
Collection: Mathematics |
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| 84 | Parkin protects human dopaminergic neuroblastoma cells against | ||
|
Summary: with SH cells (Fig. 1). We also examined the activation of another stress-activated MAP kinase, p38... -induced activation of p38 MAP kinase. Western blots of the same set of samples using antibodies that recognize total... using selective ... |
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|
Source: Feng, Jian - Department of Physiology and Biophysics, State University of New York at Buffalo |
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Collection: Biology and Medicine |
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| 85 | Cellular/Molecular Acute p38-Mediated Modulation of Tetrodotoxin-Resistant | ||
|
Summary: TNF receptor 1 (TNFR1) knock-out mice and is blocked by the p38 mitogen-activated protein kinase... -state inactivation curves. p38 mitogen-activated protein kinase modulates TTX-R Na currents and mediates... that TNF might modulate TTX-R Na currents via ... |
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|
Source: Gereau, Robert W. IV - Basic Research Division, Pain Center & Department of Anesthesiology, Washington University in St. Louis; Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis |
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|
Collection: Biology and Medicine |
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| 86 | Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK | ||
|
Summary: is negatively regulated by mammalian target of rapamycin (mTOR). The activation of p38 MAPK by GFAP accumulation... with a specific p38 inhibi- tor (SB203580), a specific JNK inhibitor (SP600125) and a potential p38/JNK ... |
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|
Source: Sulzer, David - Departments of Neurology & Psychiatry, Columbia University |
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Collection: Biology and Medicine |
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| 87 | Searching for new allosteric sites in enzymes Jeanne A Hardy and James A Wells | ||
|
Summary: with crystallography Tethering GlyP FVIIa Caspase-3 KSP Caspase-7 F16BPase PTP1B b-Lactamase p38 kinase Glucokinase HIV... . Diaryl urea inhibitors such as BIRB-796 bind to p38 MAP kinase, a serine/threonine kinase, in a new... of p38 kinase, or between the palm and ... |
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|
Source: Hardy, Jeanne - Department of Chemistry, University of Massachusetts at Amherst |
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|
Collection: Chemistry |
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| 88 | Prorein Science (1997),6:242-245. Cambridge University Press. Printed in the USA. Copyright 0 1997The Protein Society | ||
|
Summary: ;mitogen-activatedproteinkinase (MAPK); p38; RK; serinekhreonine kinase; X-ray diffraction The members of the mitogen-activated protein... of recombinant human p38 MAP kinase S. PAV,' D.M. WHITE,' S. ROGERS,' K.M. CRANE,' C.L. CYWIN,' W. DAVIDSON: J... human ... |
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|
Source: Tong, Liang - Department of Biological Sciences, Columbia University |
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Collection: Biology and Medicine |
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| 89 | These data accord with earlier studies demonstrating regulation of RGS4 expression by dopamine4 | ||
|
Summary: , Egan MF, Weinberger DR. Am J Psychiatry 2003; 160: 22092215. Activated p38 MAPK is associated... (2007) 12, 895897; doi:10.1038/sj.mp.4002025 Recent data indicate that activation of the p38 mitogen-activated... report that increased ... |
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|
Source: Maestripieri, Dario - Institute for Mind and Biology, University of Chicago |
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Collection: Biology and Medicine |
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| 90 | Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy | ||
|
Summary: are possibly mediated by p38 mitogen-activated protein kinase (MAPK) (17, 18). Ang II can also activate Jun N... 21). ERK, p38, and JNK constitute the MAPK family signaling that activates the downstream AP-1... to deliver Ang II at 450 ng/kg/min ... |
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|
Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis |
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|
Collection: Biotechnology |
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| 91 | The Roles of MAPK Cascades in Synaptic Plasticity and Memory in Aplysia: Facilitatory Effects | ||
|
Summary: - induced LTF would also block ERK activation. Role of p38-MAPK in SN-MN Synaptic Facilitation Thus far, we... was in- hibited. Second, they blocked p38-MAPK activity using specific antibodies and showed that it had... as an inhibitory constraint in the induction of ... |
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|
Source: Sharma, Shiv K. - National Brain Research Centre (India) |
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Collection: Biology and Medicine |
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| 92 | The International Journal of Biochemistry & Cell Biology 37 (2005) 679691 Mitogen-activated protein kinases and selected downstream | ||
|
Summary: (except brain) during hibernation whereas active, phosphorylated p38MAPK increased only in muscle... ; Weston and Davis, 2002). The p38MAPK cascade is also activated by stress or cytokines (Shi & Gaestel... activation overlap with those for ... |
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|
Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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|
Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 93 | JOURNAL OF EXPERIMENTAL ZOOLOGY 287:477484 (2000) 2000 WILEY-LISS, INC. | ||
|
Summary: activities rose during anoxia only in spleen (a 2.8-fold increase). JNK activity showed a significant... MAPK member is p38, which is activated by several stresses, including hyperosmolarity (Han et al., '94... , and 20 hr) or in 20-hr anoxic ... |
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|
Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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|
Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 94 | M2A1 APPLIED MATHEMATICS 1) Find and classify the four critical points of the system | ||
|
Summary: - c1HP, P = a2 - c2PH-1 P, where a1, a2, c1 and c2 are positive constants. Show that when a2 > 4a1... the single critical point is a stable node but when a2 < 4a1 the nature of the critical point changes... into the ... |
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|
Source: Gibbon, J. D. - Department of Mathematics, Imperial College, London |
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|
Collection: Mathematics |
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| 95 | A BIFUNCTIONAL ROLE FOR GROUP IIA SECRETED PHOSPHOLIPASE A2 IN HUMAN RHEUMATOID FIBROBLAST-LIKE SYNOVIOCYTE ARACHIDONIC ACID METABOLISM. | ||
|
Summary: phosphorylation of p38 MAPK, two key regulators of COX-2 protein expression, but does activate the ERK1/2 pathway... inhibition alone, may not adequately block the activity- independent function of sPLA2-IIA. Phospholipase A2... that requires phosphorylation of the ... |
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|
Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
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|
Collection: Chemistry ; Biology and Medicine |
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| 96 | Cellular Microbiology (2005) 7(5), 655665 doi:10.1111/j.1462-5822.2005.00498.x 2005 Blackwell Publishing Ltd | ||
|
Summary: of intestinal epithelial cells results in the activation of the ERK and p38 mitogen-acti- vated protein kinases... response regulation are two members of the mitogen-activated protein (MAP) kinase family, ERK and p38... to nuclear responses induced by C. jejuni, we ... |
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|
Source: Galan, Jorge E - Boyer Center for Molecular Medicine & Department of Cell Biology, Yale University |
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|
Collection: Biology and Medicine |
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| 97 | MOLECULAR AND CELLULAR BIOLOGY, June 2004, p. 51725183 Vol. 24, No. 12 0270-7306/04/$08.00 0 DOI: 10.1128/MCB.24.12.51725183.2004 | ||
|
Summary: stress-induced activation of the MAPK p38 in human carcinoma cells and was mediated... , as increasing evidence implicates both ROS and stress-activated MAPKs such as p38 and JNK in cancer cell... itself depends on p38 ... |
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|
Source: Ullrich, Axel - Max-Planck-Institut für Biochemie |
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|
Collection: Biology and Medicine |
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| 98 | Developmental Regulation of Mitogen-Activated Protein Kinase- | ||
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Summary: investigates the activation in vivo and regulation of the expression of compo- nents of the p38 mitogen-activated... . Both p38 MAPK and its up- stream activator MAPK kinase-6 (MKK6) were found to be chronically activated... ... |
|||
|
Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University |
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Collection: Biology and Medicine |
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| 99 | Michael R. Bruchas, Ph.D Assistant Professor | ||
|
Summary: ., Aita M., Xu M., Barot S., Li S., and Chavkin C. (2007) Stress-induced p38 MAPK Activation Mediates... ;4 kappa opioid activation of p38 mitogen-activated protein kinase. J. Neurosci., 27:2570-2581 16) Bruchas... M.R., Macey T.A., Lowe J., ... |
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|
Source: Bruchas, Michael R. - Department of Anesthesiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 100 | The concept of purinergic neurotransmission was pro-posed in 1972 (REF. 1), after it was shown that adenosine | ||
|
Summary: Activated microglia GLUT GLUT ATP ADP UTP/UDP ATP Glycine GABA ADOATP BDNF ERK NFAT Migration p38... and anxiety. reduced adenosinergic activity is involved in mania and aggres- sive behaviour134 and A2A... in mice lacking ... |
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|
Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London |
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|
Collection: Biology and Medicine |
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