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Sample search results for: a3 adenosine receptors

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1 doi:10.1152/ajpcell.00025.2006 291:254-265, 2006. First published Mar 29, 2006;Am J Physiol Cell Physiol
 

Summary:  A 2bA A3 Fig. 2. Localization of adenosine receptors in rat uroepithelium. Cryosections of rat bladder... that A3 receptors are not effective transducers of adenosine-mediated changes in exocytosis... , and ...

  

Source: Apodaca, Gerard - Departments of Medicine & Cell Biology and Physiology, University of Pittsburgh

 

Collection: Biology and Medicine

 
2 Agonist-induced polarized trafficking and surface expression of the adenosine 2b receptor in intestinal epithelial cells: role of SNARE proteins
 

Summary:  , and A3). Under pathological states, excess adenosine generated at inflamma- tory sites can act... 2a, A2b, and A3 receptors in the human enteric nervous system. J Comp Neurol 439: 46­64, 2001. 8... Agonist-induced polarized trafficking and surface expression of the ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
3 Adenosine A3 receptor stimulation induces protection of skeletal muscle from eccentric exercise-mediated injury
 

Summary:  Adenosine A3 receptor stimulation induces protection of skeletal muscle from eccentric exercise... , Zambraski EJ, Rader EP, Campbell KP, Liang BT. Adenosine A3 receptor stimulation induces protection... demonstrated a potent ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
4 ABSTRACT The concept of a purinergic sig-nalling system, using purine nucleotides and
 

Summary:  (ATP/adenosine diphosphate (ADP)) receptors was proposed by Burnstock in 19786. This helped resolve... , A2B and A3, and, in 1985, Burnstock and Kennedy proposed a basis for distinguishing between two... and inactivation of ATP, and autoregulation via prejunctional adenosine (P1) ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
5 For personal use only. Not to be reproduced or distributed without permission from Prous Science. Drug News Perspect 16(3), April 2003 2003 Prous Science CCC: 02140934/2003 133
 

Summary:  (A 1, A2A, A2B, A3), are activated by adenosine. 1 There are two distinct families of receptors... involved in preconditioning via activation of A 1 and A3 receptors. All four subtypes of adenosine ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
6 Pharmacology of Pain edited by Pierre Beaulieu, David Lussier, Frank Porreca, and Anthony H. Dickenson
 

Summary:  Signaling The Periphery Adenosine A1, A2A, A2B, and A3 receptors (ARs) are all present at peripheral sites... signaling in inflammatory states. Adenosine A2B and A3 receptors have not been identified directly... in chronic ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
7 The birth and postnatal development of purinergic signalling G. Burnstock,1
 

Summary:  through adenosine receptors. This suggestion was based largely on the observation that adenosine and its... that several factors including adenosine receptors, NO and KATP channels contribute, and may act... vesical parasympathetic ganglia, purines suppressed synaptic transmission ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
8 Biochemistry Insect Biochemistry and Molecular Biology 37 (2007) 318329
 

Summary:  for adenosine and adenosine receptor agonist binding in point mutation experiments for the human A1, A2A and A3... 50 values for adenosine-induced cAMP response of the human A1, A2A, A2B and A3 receptors ...

  

Source: Žurovec, Michal - Department of Physiology, University of South Bohemia

 

Collection: Biology and Medicine

 
9 Cellular/Molecular Adenosine-Evoked Hyperpolarization of Retinal Ganglion
 

Summary:  , and A3 antagonists, indicating that the response was mediated entirely by A1 receptors. The GIRK channel... 241385), A2B (10 M MRS 1706), and A3 (10 M MRS 1191) receptors had no effect on the NECA-evoked response... (A1, A2A, A2B, and ...

  

Source: Newman, Eric A. - Department of Neuroscience, University of Minnesota

 

Collection: Biology and Medicine

 
10 Purinergic Signaling and Vascular Cell Proliferation and Death Geoffrey Burnstock
 

Summary:  established.1,2 P1 receptors for adenosine, of which four subtypes (A1, A2A, A2B, and A3) have been identified... in the present review.19­21 Purines and Smooth Muscle Cell Proliferation Adenosine (P1) Receptors An early study... . Adenosine ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
11 Purinoceptors on Neuroglia Alexei Verkhrasky & Oleg A. Krishtal &
 

Summary:  to several families of Gi and Go proteins. Four types of adenosine receptors (A1, A2A, A2B and A3... ) with distinct pharmacological and functional properties were cloned [33]. As a rule, the A1 and A3 receptors... receptors ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
12 Purinergic regulation of vascular tone and remodelling
 

Summary:  ; Burnstock, 2007a). P1 receptors for adenosine, of which four subtypes (A1, A2A, A2B 63 Autonomic & Autacoid... -8673.2009.00435.x 63 Autonomic & Autacoid Pharmacology #12;and A3) have been cloned and characterized, have been... distinguished from P2 receptors for ATP, ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
13 This article was originally published in the Encyclopedia of Neuroscience published by Elsevier, and the attached copy is provided by Elsevier for the
 

Summary:  Four different P1 receptor subtypes, A1, A2A, A2B, and A3, have been cloned. All are G... -protein-coupled receptors (GPCRs). At 318 amino acids in length, the A3 subtype is the shortest, while A2A is the longest... transmembrane domain (see Figure 1(a)). P1 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
14 Adenosine-Mediated Presynaptic Modulation of Glutamatergic Transmission in the Laterodorsal Tegmentum
 

Summary:  adenosine A1 receptors (Rainnie et al., 1994). However, adenosine effects on syn- aptic inputs to LDT... IPSCs were reduced by adenosine (50 M). A presynaptic site of action for adenosine A1 receptors... , suggesting the pres- ence of a tonic activation of presynaptic ...

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
15 No evidence for cross-talk between the adenosine A1 and the serotonin-1A receptor system after chronic A1 receptor
 

Summary:  Chapter 7 No evidence for cross-talk between the adenosine A1 and the serotonin-1A receptor system... these lines, there are data suggesting cross-talk between the adenosine and serotonin receptor systems... of the adenosine A1 receptor agonist N6 ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
16 *National Institute of Child Health and Human
 

Summary:  - prises the A1 , A2A , A2B and A3 adenosine receptors, which were identified by convergent data from... of this type of receptor. A3 , the fourth distinct adenosine receptor, was identi... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
17 RESEARCH PAPER Role of ATP and related purines in inhibitory
 

Summary:  , Table 3). Effects of A1, A2A, A2B and A3 receptor antagonists on relaxations to EFS, adenosine and NECA... , inhibited the relaxations to EFS, adenosine and NECA. The lack of effect of the A1, A2B and A3 receptor... interacts ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
18 0022.3565/87/2423-0882S00.00/0 THE JOURNALor PHARMACOLOGYAND EXP!JUNENTALTHERAPEIITICS
 

Summary:  . A2 adenosine receptors. Blockade of the negative chronotropic effect of bolus Lv. injections of 2... at A1 receptors: blockade of the hypotensive effect of the same series of adenosine ago- nists was used... as an index of activity at A2 receptors. Inaddition, blockade of the ...

  

Source: Wurtman, Richard - Department of Brain and Cognitive Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
19 The Rockefeller University Press $30.00 J. Exp. Med. Vol. 206 No. 11 2417-2427
 

Summary:  , and A3 (Haskó and Pacher, 2008). T lym- phocytes express the high affinity A2A receptor as well... ). The immunoregulatory attributes of adenosine are mediated via four transmembrane adenosine receptors: A1, A2A, A2B... and neutrophils express all four ...

  

Source: Chicago, University of - Department of Microbiology

 

Collection: Biology and Medicine

 
20 Behavioral/Systems/Cognitive A Circadian Clock and Light/Dark Adaptation Differentially
 

Summary:  by the presence of retinal adenosine metabolic pathway enzymes and receptor subtypes A1 and A2A and by the effects... ) Adenosine in vertebrate retina: localization, receptor characterization, and function. Cell Mol Neurobiol 11... Adenosine in the Mammalian Retina Christophe Ribelayga ...

  

Source: Newman, Eric A. - Department of Neuroscience, University of Minnesota

 

Collection: Biology and Medicine


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21 The concept of purinergic neurotransmission was pro-posed in 1972 (REF. 1), after it was shown that adenosine
 

Summary:  the peripheral and central nervous systems4 . Separate membrane receptors for adenosine (ADO) and ATP were... -methyl-d-aspartate receptors (NMDARs). ATP is broken down by ectonucleotidase to adenosine (ADO), which acts as a presynaptic... intestine, bladder Role in allergic and inflammatory disorders; ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
22 Bruce N. Cronstein, MD You Are Not Arthur Conan Doyle
 

Summary:  . Prior studies have demonstrated that adenosine A2B receptors regulate production... Data "Adenosine A1 receptor activation stimulates SREBP1 translocation... laboratory and others indicate that adenosine A2A ...

  

Source: Wang, Da-Neng - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University

 

Collection: Biology and Medicine

 
23 Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and co-localization with the metabotropic glutamate receptor 5 in the striatum
 

Summary:  neuromodulator that binds to at least four known G-protein- coupled receptors in the brain (A1, A2A, A2B, and A3... Title Page Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and co... ; Accepted: Aug 12, 2011 #12;Abstract The adenosine ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
24 Structure based prediction of subtype-selectivity for adenosine receptor antagonists
 

Summary:  ) of ligand and decoy sets were similar. 2.2. Homology modeling of A1, A2B and A3 adenosine receptor subtypes... compounds lacking the exocyclic amine. 3.2. Initial modeling of A1, A2B, and A3 adenosine receptor subtypes... ...

  

Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
25 Perspectives in Pharmacology P2 Purinergic Receptors: Modulation of Cell Function and
 

Summary:  this response. AMP gives rise to adenosine, which acti- vates the various P1 receptors (A1, A2A, A2B, A3... with the excitatory actions of ATP on nerve cells. Adenosine (P1) receptor activation can inhibit ATP release. ATP... receptor responses ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
26 Neuropharmacology 43 (2002) 13131323 www.elsevier.com/locate/neuropharm
 

Summary:  subdivisions of P1 recep- tors, into A1, A2A, A2B and A3 and of P2 receptors into P2X and P2Y families... adenosine. This is suggestive of P2Y1-mediated relaxation and perhaps a further P2Y receptor subtype... classification of receptors for ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
27 Current Pharmaceutical Design, 2009, 15, 000-000 1 1381-6128/09 $55.00+.00 2009 Bentham Science Publishers Ltd.
 

Summary:  1, A2A, A2B, and A3 (see [53]). All P1 adenosine receptors couple to G proteins and, in common... to adenosine, it acts as a prejunctional inhibitor of transmission via P1(A2) purinoceptors. P2X3 receptors... adenosine directly [47]. C. ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
28 Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation
 

Summary:  ,23­25 and it is currently recognised that there are four subtypes of P1 receptors (A1, A2A, A2B and A3), seven subtypes of P... .burnstock@ucl.ac.uk Keywords: ATP; P2X and P2Y receptors; epithelia; immune cells; bone; cancer Abbreviations: ADP, adenosine... of purinoceptors,18,19 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
29 Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional Significance
 

Summary:  GPCRs (A1, A2A, A2b, and A3), whereas ATP activates P2X receptors, which are ion channels, as well... ; Izquierdo-Claros et al., 1997; Marzullo et al., 1999). F. Purinergic Receptors Purines such as adenosine... between adenosine and dopa- mine ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
30 TRENDS in Pharmacological Sciences Vol.22 No.4 April 2001 http://tips.trends.com 0165-6147/01/$ see front matter 2001 Elsevier Science Ltd. All rights reserved. PII: S0165-6147(00)01643-6
 

Summary:  , four subtypes of adenosine (P1) receptors were cloned [A1 , A2A , A2B and A3 (Ref. a)]. P2X receptor... 58261 Gs : cAMP A2B Large intestine, bladder NECA Enprofylline Gs : cAMP A3 Lung, liver, brain, testis... breakdown to ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
31 Purinergic signalling: therapeutic potential* GEOFFREY BURNSTOCK
 

Summary:  receptors were cloned, namely A1, A2A, A2B and A3 and in 1985, Burnstock and Kennedy proposed a basis... was the presence of purinoceptors (2). A basis for distinguishing P1 (adenosine) from P2 (ATP/ADP) receptors... in rats and dogs by the P2Y receptor agonist ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
32 Purine and pyrimidine receptors G. Burnstock
 

Summary:  . and Civelli, O. (1992) Molecular cloning and characterization of an adenosine receptor: the A3 adenosine... by ectonucleotidases. Four subtypes have been identified, A1, A2A, A2B and A3 receptors. P2 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
33 Purine and pyrimidine receptors G. Burnstock
 

Summary:  . and Civelli, O. (1992) Molecular cloning and characterization of an adenosine receptor: the A3 adenosine... and A3 receptors. P2 receptors are activated by purines and some subtypes also by pyrimidines. ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
34 A Role for Adenosine Deaminase in Drosophila Larval Development
 

Summary:  functions by binding to G protein-coupled adenosine receptors (A1, A2a, A2b, and A3 in mammals) that can... the adenosine receptor (AdoR), but fat body disintegration, which is promoted by action of the hemocytes, seems... factor-A; AdoR, Drosophila ...

  

Source: Gibson, Matt - Stowers Institute for Medical Research; Žurovec, Michal - Department of Physiology, University of South Bohemia

 

Collection: Biology and Medicine

 
35 Adenosine triphosphate as a neurotransmitter and neuromodulator Geoffrey Burnstock
 

Summary:  so far, namely A1, A2a, A2b, and A3. The first subclasses for P2-purinoceptors, proposed by Burnstock... :85-108 [MEDLINE] Ferre S, Fredholm BB, Morelli M, et al. (1997): Adenosine-dopamine receptor-receptor interactions... Adenosine triphosphate as a neurotransmitter and neuromodulator ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
36 REVIEW ARTICLE The journey to establish purinergic signalling in the gut
 

Summary:  of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system. J Comp Neurol 2001; 439: 46... cloned, namely, A1, A2A, A2B, and A3. Seven subtypes of P2X receptors have been identified... and ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
37 Physiology and Pathophysiology of Purinergic Neurotransmission
 

Summary:  receptors Four subtypes of P1 receptors have been cloned, namely, A1, A2A, A2B, and A3 (see Refs. 370, 423... /ADP, respectively), was proposed (246). At about the same time, two subtypes of the P1 (adenosine) receptor were... , 582, 1392). All P1 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
38 Colocalization and Regulated Physical Association of Presynaptic Serotonin Transporters with A3 Adenosine
 

Summary:  ; accepted June 24, 2011 ABSTRACT Activation of A3 adenosine receptors (A3ARs) rapidly enhances the activity... -activated protein kinase; A3AR, A3 subtype adenosine ...

  

Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University

 

Collection: Biology and Medicine

 
39 Evolutionary origins of the purinergic signalling system G. Burnstock1
 

Summary:  Physiological Society, doi: 10.1111/j.1748-1716.2009.01957.x 415 #12;receptors A1, A2A, A2B and A3... . These receptors are generally coupled to adenylate cyclase, activation of the A1 and A3 receptors have... in the same species, suggests that ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
40 Biochemistry Insect Biochemistry and Molecular Biology 35 (2005) 381389
 

Summary:  mechanisms involve interactions of elevated adenosine (Table 3B) with adenosine receptors on lymphocytes... -[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J. 14, 2065­2074. Heming, B... .N., Leung, E., Baraldi, P.G., Borea, P.A., 2002. ...

  

Source: Žurovec, Michal - Department of Physiology, University of South Bohemia

 

Collection: Biology and Medicine


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41 Purinergic signalling *Geoffrey Burnstock
 

Summary:  2B and A3 (see Ralevic & Burnstock, 1998). All P1 adenosine receptors are typical G protein... receptors mediating apoptotic cell death (Greig et al., 2003). ATP and adenosine have been claimed to play... . Adenosine, via A2A ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
42 pubs.acs.org/jmcPublished on Web 01/22/2010r 2010 American Chemical Society J. Med. Chem. 2010, 53, 17991809 1799
 

Summary:  expressing the human adenosine A3 receptor were kind gifts from Dr. J. Wang (Biogen/IDEC, Cambridge, MA... compound 1), and A3 ([125 I]AB-MECA) receptors as described previously in literature54 with the exception... of 100 M CPA and nonspecific ...

  

Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
43 0022.3565/86/2362.0350S02.oo/0 THE JOURN"L or PH..R COLO<:Y..,..D EXPF.H'''ENT''L THER"PEl'TIC~
 

Summary:  with specific receptors on pre- or post- synaptictissues (Dalyet 01.,1981).Presynaptically,adenosine inhibits... , particularly in tissues containing multi- ple subpopulations of adenosine receptors mediating different... analogs were also adminis- tered in an attempt to characterize the ...

  

Source: Wurtman, Richard - Department of Brain and Cognitive Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
44 Purinergic signalling in the nervous system: an overview
 

Summary:  adenosine receptors A1, A2A, A2B and A3 are G- protein coupled (Figure 1). Typically, A1 and A3 couple... /or astrocytes that release adenosine directly [18]. Receptors for purines and pyrimidines Separate membrane... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
45 The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor
 

Summary:  activated by both AMP and adenosine, and was thus renamed the P2Y15 receptor as the latest member of the P2Y... of GPR80/ GPR99 as a receptor for adenosine and AMP was surprising because of the phylogenetic distance... of the protein sequence of this receptor from the known ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
46 Genetics of caffeine consumption and responses to caffeine Amy Yang & Abraham A. Palmer & Harriet de Wit
 

Summary:  ubiquitously throughout the body. Of the four receptors that have been identified (A1, A2A, A2B, and A3), the A... of other substances. Genome association studies link variations in adenosine and dopamine receptors... conditions, the main effects of caffeine are due to competitive ...

  

Source: Das, Soma - Department of Human Genetics, University of Chicago; Ober, Carole - Committee on Genetics & Department of Human Genetics, University of Chicago

 

Collection: Biology and Medicine

 
47 In this thesis a combined approach is described to investigate the constitutive activity of G protein protein-coupled receptors (GPCRs) using human adenosine A2B receptors and to
 

Summary:  activity of G protein protein-coupled receptors (GPCRs) using human adenosine A2B receptors and to evaluate... and 4 the yeast system is exploited to study inverse agonism of the human adenosine A2B receptor... . At first, constitutively active mutant (CAM) human ...

  

Source: van den Brink, Jeroen - Leiden Institute of Physics, Universiteit Leiden

 

Collection: Physics

 
48 INTERACTION BETWEEN ATP AND NERVE GROWTH FACTOR SIGNALLING IN THE SURVIVAL AND NEURITIC OUTGROWTH FROM
 

Summary:  for adenosine (A1, A2A, A2B and A3 subtypes, all G-protein-coupled) and P2 receptors for ATP (P2X ionotropic... ., Franceschi, C., Giammarioli, A.M., Jacobson, K.A., Cattabeni, F., Malorni, W., 1998. Adenosine A3 receptors... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
49 J Physiol 589.2 (2011) pp 283295 283 The dynamics of single spike-evoked adenosine release
 

Summary:  , the modulation of adenosine release by specific G-protein coupled receptor agonists strongly suggests... mediated by glutamate receptor activation In control conditions (absence of 4-AP), adenosine release... of the adenosine release stems from AMPA receptor ...

  

Source: Richardson, Magnus - Systems Biology Centre, University of Warwick

 

Collection: Biology and Medicine

 
50 Review Article Purinergic receptor-mediated effects of adenosine 5 -triphosphate
 

Summary:  protein-coupled P1 receptor subtypes have been cloned: A1, A2A, A2B and A3.19 P2 receptors are subdivided... Review Article Purinergic receptor-mediated effects of adenosine 5 -triphosphate in urological... purinergic receptors are subdivided into ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
51 lagC-Null and gbf-Null Cells Define Key Steps in the Morphogenesis of Dictyostelium Mounds
 

Summary:  -treated gbf-null mound, this single center produced concentric waves (Figs. 3a­3c) that persisted for as long... is 3 min in a, 3 min in b, 4 min in c, and 5 min in d. Scale bars 20 m. (Movies for this and subsequent... of adenosine to the class of receptors (Kd 350 ...

  

Source: Firtel, Richard A. - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
52 Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss
 

Summary:  (Figures 3A­3C). This was not due to a downregulation of the A1 receptor, as the response to nonsaturating... that by releasing ATP, astrocytes regulate extracellular adenosine acting on synaptic A1 receptors. Astrocytes... of adenosine that acts on A1 ...

  

Source: Newman, Eric A. - Department of Neuroscience, University of Minnesota

 

Collection: Biology and Medicine

 
53 Ecto-5V-nucleotidase activity in brain membranes of zebrafish (Danio rerio)
 

Summary:  modifies cell functioning by operating G-protein-coupled receptors (A1, A2A, A2B, A3), which can inhibit (A... , studies in teleost brain have shown that adenosine A1 receptors appeared similar to that found in mammals... ) 203­207206 #12;A2A adenosine ...

  

Source: Eizirik, Eduardo - Centro de Biologia Genômica e Molecular da Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul

 

Collection: Environmental Sciences and Ecology

 
54 proteinsSTRUCTURE O FUNCTION O BIOINFORMATICS Predicted structures of agonist and
 

Summary:  complexes of adenosine A3 receptor Soo-Kyung Kim,1 Lindsay Riley,2 Ravinder Abrol,1 Kenneth A. Jacobson,3... receptor activation, while the A1 and A3 adenosine sub- types are linked to Gi proteins inhibiting c... . ...

  

Source: Goddard III, William A. - Materials and Process Simulation Center & Department of Chemistry, California Institute of Technology

 

Collection: Materials Science

 
55 Analysis of the RNA-Editing Reaction of ADAR2 with Structural and Fluorescent Analogues of the GluR-B R/G Editing Site
 

Summary:  - phoresis; TE, 10 mM TrisHCl, pH 7.5, 0.1 mM EDTA; GluR-B, glutamate receptor B subunit; ADA, adenosine... was constructed for the splint ligation 5-dCdCdTdAdAd- AdGdGdAdTdCdCdTrCrArUrUrA-3, where dC, dT, dA, and d... 17, 2000 ABSTRACT: ADARs are adenosine deaminases responsible for RNA ...

  

Source: Beal, Peter A. - Department of Chemistry, University of Utah

 

Collection: Chemistry

 
56 The Uroepithelial-associated sensory web , E Balestreire1
 

Summary:  family ErbB1­3 receptors,17 A1, A2a, A2b, and A3 adenosine receptors,18 a- and b-adrenergic receptors,19... of a3-type nicotinic receptors. Methyllcaconitine alone does not alter reflex bladder activity; ...

  

Source: Apodaca, Gerard - Departments of Medicine & Cell Biology and Physiology, University of Pittsburgh

 

Collection: Biology and Medicine

 
57 Historical review: ATP as a neurotransmitter
 

Summary:  to adenosine by ectoenzymes, so that some of the actions of ATP were directly on P2 receptors, whereas others... were due to the indirect action of adenosine on P1 receptors. At about the same time, two subtypes of P... 1 (adenosine) receptor were recognized [40] but ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
58 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  . In addition, we predicted structures for the human A1, A2B, and A3 adenosine receptors (ARs) and used... ) to A1, A2A, A2B, and A3 human adenosine receptors. The computed energies show the same trends... subtypes (A1, A2A, ...

  

Source: Goddard III, William A. - Materials and Process Simulation Center & Department of Chemistry, California Institute of Technology

 

Collection: Materials Science

 
59 ORIGINAL ARTICLE An in vivo model of melanoma: treatment with ATP
 

Summary:  -Yehuda S, Madi L, Cohn I (2002) A3 adenosine receptor as a target for cancer therapy. Anticancer Drugs 13... , Erlanger A, Ohana G, Harish A, Merimski O, Barer F, Fishman P (2004) The A3 adenosine receptor is highly... cells ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
60 Pathophysiology and Therapeutic Potential of Purinergic Signaling
 

Summary:  subtypes of P1 receptors were cloned, namely, A1, A2A, A2B, and A3. In 1985, Burnstock and Kennedy proposed... Y receptors in endothelial cells to release nitric oxide (NO), resulting in relaxation. Adenosine... ). The therapeutic poten- tial of adenosine A2A ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London; Saunders, Mark - Benfield Hazard Research Centre, Department of Space and Climate Physics, University College London

 

Collection: Biology and Medicine ; Geosciences


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61 Editorial Manager(tm) for Nuclear Medicine Communications Manuscript Draft
 

Summary:  there are still controversies on how adenosine receptors (A1, A2A, A2B, and A3) mediate the cardioprotection... depends critically on the duration of the stimulus and involves both A(1) and A(3) receptors. Cardiovasc... and relates with the ...

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine

 
62 Purines and Sensory Nerves Geoffrey Burnstock
 

Summary:  , this was prevented by the breakdown product, adeno- sine, via A3 receptors (Zhang et al. 2006). Evidence has been... of receptors for purines and pyrimidines are available, including four subtypes of P1 (adenosine), seven... and internalization of P2Y receptors in ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
63 Adenosine is crucial for deep brain stimulationmediated attenuation of tremor
 

Summary:  , resulting in accumulation of its catabolic product, adenosine. Adenosine A1 receptor activation depresses... infusion of A1 receptor agonists directly reduces tremor, whereas adenosine A1 receptor­null mice show... notion that caffeine, a nonselective ...

  

Source: Newman, Eric A. - Department of Neuroscience, University of Minnesota

 

Collection: Biology and Medicine

 
64 D2/D3 Dopamine Receptor Heterodimers Exhibit Unique Functional Properties*
 

Summary:  for heterodimerization has recently been provided for dopamine D1 and adenosine A1 receptors as well as for dopamine D2... receptor forms hetero-oligomers with the adenosine A1 receptor. As the issue of G protein-coupled receptor... 3.55 0.98b D3 ...

  

Source: Vogel, Zvi - Department of Neurobiology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
65 Nature Macmillan Publishers Ltd 1997 arterial blood sampling (0.5 ml samples) and
 

Summary:  , observed after blockade of peripheral adenosine receptors, and was not specific for caffeine. This find... reduction after antagonist with- drawal, suggests receptor-mediated regula- tion of the plasma adenosine... in the world1 , with actions mediated primarily by adenosine ...

  

Source: Wurtman, Richard - Department of Brain and Cognitive Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
66 Purinergic receptors Brian F. King and Geoffrey Burnstock
 

Summary:  et al. 2001). In contrast, some synthetic nucleotides--ADPS, ATPS, and A3P5PS-- are partial agonists... ). The P2Y1 receptor closes the N-type Ca2+ channel in neurones, with both adenosine triphosphates... Chapter 21 Purinergic receptors Brian F. King and Geoffrey Burnstock 21.1 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
67 Postnatal development of P2 receptors in the murine gastrointestinal tract
 

Summary:  further subdivided into A1, A2A, A2B and A3. P2 receptors have been divided into two families (Ab... ¼ adenosine, suggesting P2Y1 receptors. This was supported by the sensitivity of responses to 2-Me... equipotent suggesting a P2Y2 and/or P2Y4 receptor. ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
68 ADENOSINE, PROLONGED WAKEFULNESS, AND A1-ACTIVATED NF-UB DNA BINDING IN THE BASAL FOREBRAIN OF THE RAT
 

Summary:  of adenosine increased NF-UB DNA binding while pretreatment of the slices with the A1 adenosine receptor... during prolonged wakefulness, act through an A1 adenosine receptor and a second messenger system... of the highly selective A1 adenosine ...

  

Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University

 

Collection: Biology and Medicine

 
69 2001 Wiley-Liss, Inc. DRUG DEVELOPMENT RESEARCH 52:110 (2001)
 

Summary:  were cloned, namely, A1, A2A, A2B, and A3 [Ralevic and Burnstock, 1998]. P2X Receptor Family P2X... , 1976a], and a basis for distinguishing P1 (adenosine) from P2 (ATP/ADP) receptors was pro- #12... :246­254. Vainio M, Törnquist K. 2000. The role of adenosine A1 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
70 International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors
 

Summary:  -methylthio-9H-purin-9-yl-1-diphosphoryl- oxymethyl]bicyclo[3.1.0]hexane-2,3-diol; A3P5P, adenosine 3 ,5... -cyanato phenyl)-thioureido]butane; A3P5PS, adenosine 3 - phosphate 5 phosphosulfate; RT-PCR, reverse... and Weetman, 1976), receptors for ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
71 UCB Pharma research day--25 October 2007 `Glia-neuron interactions and purinergic receptors
 

Summary:  and A3), seven subtypes of P2X ligand-gated ion channel receptors (P2X1-7) and eight subtypes of P2Y... receptors for adenosine and AMP (named P1 receptors) and for ATP and ADP (named P2 receptors) were proposed... UCB Pharma research day--25 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
72 The American Journal of Physiology, Renal Physiology --Manuscript F-00256-2007 --
 

Summary:  mechanism of renal blood flow autoregulation and the autoregulatory role of A1 adenosine receptors in mice... to A1-adenosine receptor (A1AR) -agonist cyclohexyl-adenosine (CHA). Time course of the response

  

Source: Just, Armin - Physiologisches Institut I, Albert-Ludwigs-Universität Freiburg

 

Collection: Biology and Medicine

 
73 The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle
 

Summary:  receptor antagonist, abolished inhibitory effects of adenosine at all three temperature conditions but did... AM), a nonselective P2 receptor antagonist, inhibited the action of ATP but not adenosine, while... for ATP taken at three temperature conditions tested. 3.1.2. P1 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
74 Neuron, Vol. 38, 417432, May 8, 2003, Copyright 2003 by Cell Press ATP-Sensitive Potassium Channel Traffic Regulation
 

Summary:  ). Adenosine A1- and A3-receptors, identified as may serve as a central mediator in ischemic precondi- part... metabolic lar myocytes, adenosine receptor stimulation and stress is protective against injury, excessive... internalization in cardiac myocytes by activat- ...

  

Source: Lim, Wendell - Departments of Cellular and Molecular Pharmacology & Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine

 
75 Adenosine does not save the heart of anoxia-tolerant vertebrates during prolonged oxygen deprivation
 

Summary:  interaction with at least four (i.e., A1, A2A, A2B and A3) cell membrane receptors (Newby, 1984; Newby et al... of the non-specific adenosine receptor antagonist aminophylline while measuring cardiac output (Q), heart... and Stecyk, in press). Given the receptor- and ...

  

Source: Farrell, Anthony P. - Faculty of Land and Food Systems, University of British Columbia

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
76 Copyright C Blackwell Munksgaard 2002 Traffic 2002; 3: 866877
 

Summary:  Membrane preparations expressing WT, NQ and F251A (3mg total protein) or NQ/N296A (20mg total protein) C5a... , Strnad J, Pausch MH, Hadcock JR. Pharmacological char- acterization of the rat A2a adenosine receptor... -9219 Constitutive Activation and Endocytosis of the Complement Factor 5a ...

  

Source: Bourne, Henry - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
77 Rapid Stimulation of Presynaptic Serotonin Transport by A3 Adenosine Receptors
 

Summary:  Rapid Stimulation of Presynaptic Serotonin Transport by A3 Adenosine Receptors Chong-Bin Zhu... adenosine receptors (A3AR) stimulates SERT activity via both PKG and p38 MAPK (Zhu et al., 2004a). Whether ...

  

Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University

 

Collection: Biology and Medicine

 
78 Principal Investigator/Program Director (Last, first, middle): PHS 398/2590 (Rev. 05/01) Page 1 Biographical Sketch Format Page
 

Summary:  suffixes such as 3a, 3b. BIOGRAPHICAL SKETCH Provide the following information for the key personnel... /99, proposed to be the P2Y15 receptor activated by adenosine and AMP, is not a P2Y receptor. Purinergic... the application. Do not use suffixes such as 3a, ...

  

Source: Elston, Timothy C. - Department of Pharmacology, University of North Carolina at Chapel Hill

 

Collection: Mathematics ; Biology and Medicine

 
79 Adenosine Released by Astrocytes Contributes to Hypoxia-Induced Modulation of Synaptic Transmission
 

Summary:  of excitatory synaptic transmission me- diated by activation of presynaptic A1 adenosine receptors. The glia... -specific metabolic inhibitor fluorocitrate (FC) was as effective as the A1 adenosine receptor antagonist CPT... the excitatory synaptic transmission through the release of ...

  

Source: Newman, Eric A. - Department of Neuroscience, University of Minnesota

 

Collection: Biology and Medicine

 
80 J Physiol 586.14 (2008) pp 33073312 3307 TOPICAL REVIEW
 

Summary:  and A3 subtypes), P2X ionotropic receptors (P2X1­7 subtypes forming both homomultimers... be an extracellular messenger. However, after receptor subtypes for ATP and its breakdown product, adenosine, were... in purinergic signalling 3309 purines and pyrimidines have been identified: P1 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine


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81 MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/98/$04.00 0
 

Summary:  was highly selective overall: very few A3G tran- sitions occurred at non-amber/W adenosines, and the majority... change at the amber/W site, only 0.05% of all other adenosines showed A3G transitions. By extrapolating... sequenced, only three ...

  

Source: Bass, Brenda L. - Departments of Biochemistry & Human Genetics, University of Utah

 

Collection: Biology and Medicine

 
82 of May 17, 2010 This information is current as
 

Summary:  of the various com- pounds for the adenosine A3 receptor (54). Together these results in- dicate that adenosine... and A3 adenosine receptors. Studiesperformedontissuebiopsiesfrompatientswithinflammatory ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
83 This article was originally published in the Encyclopedia of Neuroscience published by Elsevier, and the attached copy is provided by Elsevier for the
 

Summary:  .deaminase Inosine Smooth muscle receptors P2 Purinoceptor 5 -nucleo- ATP resynthesis Adenosine Adenosine uptake... vasoconstriction (+) via P2X receptors on the muscle cells. Adenosine (ADO), resulting from rapid breakdown of ATP... also: Adenosine; ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
84 Progress in Neurobiology 65 (2001) 107134 P2X receptors in peripheral neurons
 

Summary:  SATP (1 mM), (7.1), Suramin (6.5), bg-me-D-ATP (13 mM), PPADS (6.4) Ap5A (3 mM) Nodose, petrosal, Suramin... Progress in Neurobiology 65 (2001) 107­134 P2X receptors in peripheral neurons Philip M. Dunn, Yu... Abstract P2X receptors are a family of ligand-gated ion channels, activated by extracellular ATP. ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
85 Kidney International, Vol. 64 (2003), pp. 13891397 Unusual absence of endothelium-dependent or -independent
 

Summary:  - sions followed: P1 receptors into A1, A2A, A2B, and A3 and P2 receptors into P2X and P2Y subtypes based... that receptors selective for adenosine and adenosine mo- nophosphate (AMP) be designated P1-purinoceptors... ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
86 Annu. Rev. Biophys. Biomol. Struct. 2003. 32:37597 doi: 10.1146/annurev.biophys.32.110601.142520
 

Summary:  ligands. The receptors involved in these studies include human A3 adenosine receptor (10, 11), rat... reported, a mutant adenosine A3 receptor (H7.43[272]E) was developed, and the binding of amine... ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
87 Faculty Competition for Post-Doctoral Fellows Shane Perrine, Psychiatry
 

Summary:  , Physiology Adenosine Receptor Modulation of Post Myocardial Infarction Fibroblast Function Patrick Mueller

  

Source: Cinabro, David - Department of Physics and Astronomy, Wayne State University

 

Collection: Physics

 
88 http://tpx.sagepub.com Toxicologic Pathology
 

Summary:  active at times of very early injury. Keywords. Adenosine receptor; arteriopathy; coronary; canine; gene... biomarkers for the clinical diagnosis of acute vascular damage. Adenosine and many adenosine receptor... blood flow (Stepp et al., 1996). Adenosine ...

  

Source: Zhao, Hongyu - School of Public Health, Yale University

 

Collection: Biology and Medicine

 
89 doi:10.1152/physiolgenomics.00068.2005 23:89-102, 2005. First published Jul 26, 2005;Physiol. Genomics
 

Summary:  , adenosine receptors (subtypes A1, A2A, A2B, and A3), to exert a variety of physiological effects (27... inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network... Weng, and Jiang-Fan Chen. Genetic and pharmacological ...

  

Source: Weng, Zhiping - Center for Advanced Genomic Technology, Boston University

 

Collection: Biotechnology

 
90 J Neural Transm (2007) 114: 4975 DOI 10.1007/s00702-006-0589-0
 

Summary:  cells were stably transfected with a double hemagglutinin-tagged (HA-tagged) dog adenosine A2A receptor... clear that methylxanthines may act as adenosine receptor antagonists (Fredholm et al., 1976) to produce... Intramembrane receptor­receptor interactions: a novel principle in ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
91 ne of the first and most enduring facts most students learn in biology class is
 

Summary:  ] Adenosine triphosphate (ATP) PhosphateAdenosine Energy trapped in bonds ATP ATP ADP P2X receptor P2Y... designated P2 receptors) and for its final breakdown product, adenosine (which he called P1 receptors). Fur... . P2Y receptors also recognize ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
92 Introduction Chapter 1 1 Introduction
 

Summary:  of cyclic adenosine monophosphate (cAmp)216,217 . The Serotonin Club Receptor Nomenclature Committee... proteins called receptors, regulate the signaling pathways that enable cells to communicate... family of receptors that are coupled to heterotrimeric guanine nucleotide binding proteins, and which

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
93 MOLECULAR AND CELLULAR BIOLOGY, Mar. 1995, p. 13891397 Vol. 15, No. 3 0270-7306/95/$04.00 0
 

Summary:  receptor subunits in the brain (19, 24, 37). To visualize the distribution of the dsRNA adenosine deaminase... -Specific Adenosine Deaminase MARY A. O'CONNELL,1 SABINE KRAUSE,1 MIYOKO HIGUCHI,2 J. JUSTIN HSUAN,3 NICHOLAS F. TOTTY... for modification 1 December 1994/Accepted 15 December 1994 Double-stranded RNA (dsRNA)-specific ...

  

Source: Jenny, Andreas - Department of Developmental and Molecular Biology , Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
94 proteinsSTRUCTURE O FUNCTION O BIOINFORMATICS GPCR 3D homology models for ligand
 

Summary:  -triazolo-pyrimidine (PTP) scaffold that yields highly specific ligands for both A1 and A3 adenosine receptor subtypes... learned from blind predictions of adenosine A2a receptor complex Vsevolod Katritch,1 Manuel Rueda,2 Polo... - mined high resolution structures of ...

  

Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
95 Endothelium-Derived Vasoconstriction by Purines and Pyrimidines
 

Summary:  by To¨lle et al1 claims to show for the first time that adenosine 5 -tetraphosphate (AP4) is released... , that AP4 is the most potent mediator of vascular smooth muscle constric- tion via P2X1 receptors or... in response to sheer stress produced by changes in blood flow act largely on P2Y receptor subtypes (but also

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
96 Inhibitory eects of some purinergic agents on ecto-ATPase activity and pattern of stepwise ATP hydrolysis in rat liver plasma membranes
 

Summary:  .570) s Reactive blue 2 (4.297)EAp4A (3.268) s pyridoxalphosphate-6-azophenyl-2P,4P-disulfonic acid (PPADS) (2... -nucleotide pyrophosphatase (EC 3.6.1.9) [11]. The adenosine formed either inter- acts with its own P1 receptors to trigger... 0.040 Ap4A 3.268 þ 0.030 ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
97 RNA EDITING BY ADENOSINE DEAMINASES THAT ACT ON RNA
 

Summary:  Syntaxin (F56A8.7a) 3 UTR Laminin- (C54D1.5) 3 UTR 36A (C35E7.6) 3 UTR SSADH (F45H10.1) 3 UTR 12A (D2024... RNA EDITING BY ADENOSINE DEAMINASES THAT ACT ON RNA Brenda L. Bass Department of Biochemistry... An Overview of RNA Editing by Adenosine Deamination . . . . . . . . . . . . . . 818 THE ENZYME FAMILY

  

Source: Bass, Brenda L. - Departments of Biochemistry & Human Genetics, University of Utah

 

Collection: Biology and Medicine

 
98 ATP signalling in epilepsy Ashwin Kumaria & Christos M. Tolias &
 

Summary:  and is believed to inhibit distant synapses by acting on adenosine receptors. Such a mechanism is consistent... hippocampal region have the opposite effect to A1 receptors in a piriform cortex kindling model. Adenosine... - leptogenesis [14], although the expression and function of ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
99 Neurons respond to a variety of attractive and repulsive guid-ance cues to navigate to their targets1. Genetic, biochemical and
 

Summary:  express high levels of EphA3 recep- tors and are repelled by target tissues expressing high levels... Dorsal and ventral UNC-129 disrupted dorsal guidance N T A P EphA3 Ephrin-A2Ephrin-A2 Ephrin-A E5 phrin... the domain of EphA3 expression in the developing chick ...

  

Source: Bargmann, Cori - Laboratory of Neural Circuits and Behavior, Rockefeller University

 

Collection: Biology and Medicine

 
100 Samenvatting In dit proefschrift wordt een gecombineerde aanpak besproken om aan de hand van de
 

Summary:  adenosine A2B receptor de constitutieve activiteit van aan G-eiwitten gekoppelde receptoren (GPCRs) te... wordt dit gistsysteem gebruikt om invers agonisme van de adenosine A2B receptor van de mens te... . In hoofdstuk 5 is de activering van de adenosine A2B receptor ...

  

Source: van den Brink, Jeroen - Leiden Institute of Physics, Universiteit Leiden

 

Collection: Physics


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