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Sample search results for: a-i mimetic peptides

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1 Miniaturized proteins: the backbone cyclic proteinomimetic approach. The field of proteinomimetics utilizes peptide-based molecules to mimic
 

Summary:  of proteinomimetics utilizes peptide-based molecules to mimic native protein functions. We describe a novel general... method for mimicking proteins by small cyclic peptides for the purpose of drug design, and demonstrate... its applicability on bovine pancreatic trypsin inhibitor (BPTI). These unique cyclic peptides, which

  

Source: Kasher, Roni - Zuckerberg Institute for Water Research, Zuckerberg Institute for Water Research, Jacob Blaustein Institutes for Desert Research

 

Collection: Environmental Sciences and Ecology ; Environmental Management and Restoration Technologies

 
2 A Mimetic Iterative Scheme for Solving Biharmonic Equations
 

Summary:  ]. An application of Green-Gauss-Stokes theorem (13) shows that the mimetic Helmholtz operator, (-D·G+aI+B ·G... 's condition, u/n + u = 0 with > 0, as the following expression (-D · G + aI + B · G + )uh = fh. (17) 6 #12;In... A Mimetic Iterative Scheme for Solving Biharmonic Equations A. ...

  

Source: Raydan, Marcos - Escuela de Computación, Universidad Central de Venezuela

 

Collection: Mathematics

 
3 Biol. Lett. (2007) 3, 463466 doi:10.1098/rsbl.2007.0234
 

Summary:  0 6 4 2 0 6 4 2 0 6 4 2 0 1.0 0.5 1.0 0.5 1.0 time (s) frequency(kHz) (a) (i) (ii) (iii) (iv) (v) (b... behaviour Female preferences drive the evolution of mimetic accuracy in male sexual displays Seth William... of interspecific vocal mimicry is unclear. Here we use spectrographic cross-correlation to compare ...

  

Source: Borgia, Gerald - Department of Biology, University of Maryland at College Park; Patricelli, Gail - Section of Evolution and Ecology, University of California, Davis

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
4 Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors
 

Summary:  displayed in an EGFR-derived peptide platform ÔAc-Asp-Ala-Asp-Glu- Xxx-Leu-NH2Õ (where Xxx = pTyr mimetic... , TEA, DMAP, AcCN; (b) LiOH, THF:H2O = 1:1. Scheme 2. Reagents: (a) i--NaN3, DMF; ii--H2, 10% Pd/C, 35... Tyr mimetics 22­24 were examined. Peptides with ...

  

Source: Wlodawer, Alexander - Macromolecular Crystallography Laboratory, National Cancer Institute

 

Collection: Chemistry ; Biology and Medicine

 
5 a g Hybrid Peptides that Contain the Conformationally Constrained Gabapentin Residue: Characterization of Mimetics of Chain Reversals
 

Summary:  structures. Keywords: amino acids ¥ beta-turn mimetics ¥ hydrogen bonds ¥ peptides ¥ structure elucidation... . J. 2003, 9, 4789 ± 47954794 mimetics in an a ± g peptide sequence. The possibility of extending... . DeGrado, Chem. Rev. 2001, 101, 3219 ± 3232; g) D. L. Steer, R. A. Lew, P. Perlmutter, ...

  

Source: Balaram , P. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
6 Current Protein and Peptide Science, 2005, 6, 000-000 1 1389-2037/05 $50.00+.00 2005 Bentham Science Publishers Ltd.
 

Summary:  properties of this particular peptide [66]. 3. COLORIMETRIC BIO-MIMETIC MEMBRANE ASSEMBLIES A recent... Current Protein and Peptide Science, 2005, 6, 000-000 1 1389-2037/05 $50.00+.00 © 2005 Bentham... Science Publishers Ltd. Membrane Interactions of Host-defense Peptides Studied in Model Systems Raz

  

Source: Jelinek, Raz - Department of Chemistry, Ben-Gurion University

 

Collection: Chemistry ; Biology and Medicine

 
7 Protein Science (1998), 7:123-131. Cambridge University Press. Printed in the USA. Copyright 0 1998 The Protein Society
 

Summary:  -H-H-H-H-H-H-H-H-H L-Q-M-N-K-K-D-M-V-A-I-K-H-L-L-S-E H-H-H-H-H-H-H-H-B-B-B-B-B-B-B-H-H H-H-H-H-H-H-H-H... ,Gierasch LM. 1993. Conformational behavior of Escherichia coli omp A signal peptides in membrane mimetic... The Protein Society Folded conformations of antigenic peptides from riboflavin carrier protein ...

  

Source: Balaram , P. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
8 Molecules 2011, 16, 774-789; doi:10.3390/molecules16010774 ISSN 1420-3049
 

Summary:  biotin and sugar mimetics. However, the full "mimicry" of these peptides has not yet been fully... mimetic. If the natural ligand is a small-molecule then the phage-selected peptides are mimics... - molecules and their mimetic peptides are often very different ...

  

Source: Orner, Brendan Patrick - Division of Chemistry and Biological Chemistry, Nanyang Technological University

 

Collection: Biology and Medicine ; Chemistry

 
9 Reversible SheetTurn Conformational Change of a Cell-Penetrating Peptide in Lipid Bilayers Studied by
 

Summary:  correlation spectra of labeled penetratin in DMPC/DMPG membranes (8:7) at P/L=1:15. (a) (I5, Q8, K13)-labeled... conformational change. The turn/sheet intensity ratios, Keq, are plotted as a function of temperature. (a) I3. (b... , 53­63. 43. Yao, X. L. & Hong, M. (2004). Structural distribution in an ...

  

Source: Hong, Mei - Department of Chemistry, Iowa State University

 

Collection: Chemistry

 
10 A Novel Substrate Mimetic Inhibitor of PKB/Akt Inhibits Prostate Cancer Tumor Growth in Mice by Blocking the PKB Pathway
 

Summary:  peptide substrate mimetic inhibitor of protein kinase B (PKB/ Akt). The compound selectively kills... of a substrate mimetic PKB inhibitor. Previous attempts to convert substrate peptides into inhibitors using... , we have overcome these limitations by chemically modifying the peptide ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
11 MaterialsScienceandEngineeringDepartmentSpecialSeminar 12:00 p.m. Thursday, February 10, 2011
 

Summary:  systems involving de novo designed peptide and peptido- mimetics, block copolymers and nanoparticles... of Illinois at Urbana-Champaign www.matse.illinois.edu Hybrid Biomaterials Based on Peptide-Polymer Conjugates... that will be critical to mimic materials found in nature. Bio-inspired building blocks, such as ...

  

Source: Shim, Moonsub - Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign

 

Collection: Materials Science

 
12 Letters in Peptide Science 5: 101103, 1998. KLUWER/ESCOM
 

Summary:  Letters in Peptide Science 5: 101­103, 1998. KLUWER/ESCOM © 1998 Kluwer Academic Publishers... . Printed in the Netherlands. 101 LIPS 257 Synthesis of a bicyclic BPTI mimetic containing 4-thioproline... 1997 Key words: backbone cyclic peptides, bovine pancreatic trypsin inhibitor, BPTI, peptidomimetic

  

Source: Kasher, Roni - Zuckerberg Institute for Water Research, Zuckerberg Institute for Water Research, Jacob Blaustein Institutes for Desert Research

 

Collection: Environmental Sciences and Ecology ; Environmental Management and Restoration Technologies

 
13 Available online at www.sciencedirect.com Peptides and peptidomimetics as prototypes
 

Summary:  ] and b-sheet [2] by smart modeling, the use of peptides and their mimetics has been a highly fruitful... opinions from established scientists who have helped to shape research on peptides and their mimetics over... Available online at www.sciencedirect.com Peptides and peptidomimetics as ...

  

Source: Raines, Ronald T. - Departments of Biochemistry & Chemistry, University of Wisconsin at Madison

 

Collection: Chemistry ; Biology and Medicine

 
14 Influence of Lysine N -Trimethylation and Lipid Composition on the Membrane Activity of
 

Summary:  of the Cecropin A-Melittin Hybrid Peptide CA(1-7)M(2-9) Vitor Teixeira,,§ Maria J. Feio,§ Luis Rivas,| Beatriz G... studies have pointed out the promising role of antimicrobial peptides (AMPs) as therapeutical agents... , their translation into clinical research is being slow due to the limitations intrinsic to their peptide ...

  

Source: Pompeu Fabra, Universitat - Departament de Ciències Experimentals i de la Salut, Proteomics and Protein Chemistry Unit

 

Collection: Biotechnology

 
15 New syntheses of tetrazolylmethylphenylalanine and O-malonyltyrosine as pTyr mimetics for the design of STAT3
 

Summary:  New syntheses of tetrazolylmethylphenylalanine and O- malonyltyrosine as pTyr mimetics... the pTyr-binding pocket of the STAT3 SH2 domain led us to develop a novel synthesis of two pTyr mimetics... dimerization identified L-OMT as the first nonphosphorus pTyr mimetic so far reported against STAT3 SH2 domain

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
16 Peptide-and Aptamer-Functionalized Nanovectors for Targeted
 

Summary:  -angiogenic cancer-targeted deliveryo Collagen-mimetic peptide Cancer-targeted deliveryp P0 immunoglobin derived... with doxorubicin inhibited growth by 66% 83 . Collagen-mimetic peptides have been developed to target the CD44... with the collagen IV-mimetic peptide ...

  

Source: Kokkoli, Efie - Department of Chemical Engineering and Materials Science, University of Minnesota

 

Collection: Materials Science

 
17 General introduction: Peptides as a promising source of therapeutic agents
 

Summary:  an adequate chemical modification. Since the number of peptides and peptide mimet- ics to choose from... #12;General introduction: Peptides as a promising source of therapeutic agents Marcelo F. Masman C1... knowledge of synthetic amino acids, peptides and peptidomi- metic compounds. The ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
18 Self-assembly and applications of biomimetic and bioactive peptide-amphiphiles
 

Summary:  to unique fibronectin-mimetic peptide sequences. Ashish Garg Jennifer A. Craig 1016 | Soft Matter, 2006, 2... on the self-assembly of model collagen mimetic peptide-amphiphiles.43 They con- nected a (Gly-Pro-Hyp)4-[IV-H1... -helical collagen- mimetic (Gly-Pro-Hyp)4-[IV-H1] ...

  

Source: Kokkoli, Efie - Department of Chemical Engineering and Materials Science, University of Minnesota

 

Collection: Materials Science

 
19 The inability of lactic acid bacteria to synthesize a large number of amino acids necessitates the presence of a proteolytic system in those environments where protein is the
 

Summary:  in the presence of various peptides or peptide mimetics (Chapter 4). The results showed that the DtpT protein... in three compartments: an extracellularly located proteinase, three membrane-bound peptide transporters... and utilization of peptides in L.lactis. The sequence of events in ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
20 A synthetic peptide with estrogen-like activity derived from a phage-display peptide library
 

Summary:  activity in rat tissues in vivo. This approach can be employed to design peptide mimetic for other hormones... as well. © 2002 Elsevier Science Inc. All rights reserved. Keywords: Steroid-mimetic peptides; Monoclonal... in the past decade to identify short peptide ...

  

Source: Kasher, Roni - Zuckerberg Institute for Water Research, Zuckerberg Institute for Water Research, Jacob Blaustein Institutes for Desert Research

 

Collection: Environmental Sciences and Ecology ; Environmental Management and Restoration Technologies


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21 Protein Farnesyltransferase from Trypanosoma brucei A HETERODIMER OF 61-AND 65-kDa SUBUNITS AS A NEW TARGET FOR ANTIPARASITE THERAPEUTICS*
 

Summary:  those against mammalian PFT and PGGT-I (Table II). The non-peptide CaaX mimetic SCH-44342 is 2 orders... ., Gibbs, J. B., Graham, S. L., Hartman, G. D., Oliff, A. I., and Smith, R. L. (1996) J. Med. Chem. 39... to T. brucei PFT with sub-micromolar affinity, and affin- ity chromatography using this ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
22 Non-natural, sequence-specific peptidomimetic oligomers are being designed to mimic bioactive peptides, with potential
 

Summary:  peptides, with potential therapeutic application. Cationic, facially amphipathic helical -peptide oligomers... have been developed as magainin mimetics. Non-natural mimics of HIV-Tat protein, lung surfactant... proteins, collagen, and somatostatin are also being developed. Pseudo-tertiary structure in ...

  

Source: Barron, Annelise E. - Department of Bioengineering, Stanford University

 

Collection: Materials Science ; Biotechnology

 
23 Development of a Potent Bcl-xL Antagonist Based on r-Helix Mimicry Olaf Kutzki, Hyung Soon Park, Justin T. Ernst, Brendan P. Orner, Hang Yin, and
 

Summary:  .edu. Figure 1. (A) i, i + 3, and i + 7 substituents of an R-helix. (B) Compounds tested in the fluorescence... . 2001, 3, 173-182. (b) Lugovskoy, A. A.; Degterev, A. I.; Fahmy, A. F.; Zhou, P.; Gross, J. D.; Yuan, J... -helix. We have synthesized several designed proteo- mimetics based on ...

  

Source: Orner, Brendan Patrick - Division of Chemistry and Biological Chemistry, Nanyang Technological University

 

Collection: Biology and Medicine ; Chemistry

 
24 Current Protein and Peptide Science, 2010, 11, 000-000 1 1389-2037/10 $55.00+.00 2010 Bentham Science Publishers Ltd.
 

Summary:  Current Protein and Peptide Science, 2010, 11, 000-000 1 1389-2037/10 $55.00+.00 © 2010 Bentham... Abstract: The growing interest in membrane interactions of amyloidogenic peptides and proteins emanates... binding of amyloidogenic peptides and amyloid peptide association with cellular membranes is critical

  

Source: Jelinek, Raz - Department of Chemistry, Ben-Gurion University

 

Collection: Chemistry ; Biology and Medicine

 
25 Design, Synthesis, and Evaluation of Peptides with
 

Summary:  , VSWFFE (EMP-1) and VSWFFED (EMP-2) (EMP: estrogen-mimetic peptide), bind mAb-E2 with high affinity (IC50... . Biopolymers (Pept Sci) 76: 404­420, 2004 Keywords: estrogen-mimetic peptides; estrogen receptor alpha... peptide VSWFFE (EMP-1) and a 7-residue peptide ...

  

Source: Kasher, Roni - Zuckerberg Institute for Water Research, Zuckerberg Institute for Water Research, Jacob Blaustein Institutes for Desert Research

 

Collection: Environmental Sciences and Ecology ; Environmental Management and Restoration Technologies

 
26 Mater. Res. Soc. Symp. Proc. Vol. 1346 2011 Materials Research Society DOI: 10.1557/opl.2011.1002
 

Summary:  of a patient during therapy is unmet. A bead-based assay with peptide antigen mimetics has been developed... . Alemtuzumab (anti-CD52) and rituximab (anti-CD20) antigen mimetic peptides, as discovered by phage display... this detection limit was the implementation of a compensation scheme where two antigen ...

  

Source: Kummel, Andrew C. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Chemistry

 
27 Molecular dynamics simulations of peptides on a hydrophilic-
 

Summary:  Chapter 4 Molecular dynamics simulations of peptides on a hydrophilic- hydrophobic interface #12... . As a start here we focus on the interaction of peptides with bilayers. A wide range of surface active... peptides have been described in the literature. For example, certain peptides are known to undergo

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
28 Miniaturized Proteins: The Backbone Cyclic Proteinomimetic Approach
 

Summary:  (Laskowski, Jr & Kato, Figure 2. Structure of the BPTI mimetic backbone bi- cyclic peptide library. The disul... than that of the best BC BPTI mimetic (peptide 16, Ki 4.0 mM). This discrepancy may be due... mimetic containing 4- thioproline replacing Cys38 . Letters ...

  

Source: Kasher, Roni - Zuckerberg Institute for Water Research, Zuckerberg Institute for Water Research, Jacob Blaustein Institutes for Desert Research

 

Collection: Environmental Sciences and Ecology ; Environmental Management and Restoration Technologies

 
29 Effect of Linker and Spacer on the Design of a Fibronectin-Mimetic Peptide Evaluated via Cell Studies and AFM Adhesion Forces
 

Summary:  Effect of Linker and Spacer on the Design of a Fibronectin-Mimetic Peptide Evaluated via Cell... , 2007. ReVised Manuscript ReceiVed March 11, 2008 The design of a fibronectin-mimetic peptide... for the rational design of any protein-mimetic peptide with two binding ...

  

Source: Kokkoli, Efie - Department of Chemical Engineering and Materials Science, University of Minnesota

 

Collection: Materials Science

 
30 Post-translational modification of the therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin
 

Summary:  for the regulation of the production of red blood cells. We selected an EPO peptide mimetic (EMP1) of 13 amino acids... Post-translational modification of the therapeutic peptides by NisB, the dehydratase... in the activity and receptor specificity of biologically active peptides. In addition, a dehydroamino ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
31 Tripeptide Inhibitors of Yersinia Protein-Tyrosine Phosphatase Kyeong Lee,a
 

Summary:  -Bn esters. As shown in Table 1, peptides 12, 13, and 15 that con- tain dicarboxy-based pTyr mimetics as well... , respectively. Surprisingly, dicarboxy pTyr mimetic-containing tri- peptides 14, 16, and 17 that previously... . Although discrepancies in PTP1B inhibitory potencies for pTyr ...

  

Source: Wlodawer, Alexander - Macromolecular Crystallography Laboratory, National Cancer Institute

 

Collection: Chemistry ; Biology and Medicine

 
32 DOI: 10.1021/la902571q 1953Langmuir 2010, 26(3), 19531959 Published on Web 10/30/2009 pubs.acs.org/Langmuir
 

Summary:  .acs.org/Langmuir © 2009 American Chemical Society Self-Assembly of Fibronectin Mimetic Peptide-Amphiphile Nanofibers... -binding motifs are promising as tissue engineering scaffolds. A fibronectin-mimetic peptide sequence... frequentlychoosetodesign a mimetic peptide ...

  

Source: Kokkoli, Efie - Department of Chemical Engineering and Materials Science, University of Minnesota

 

Collection: Materials Science

 
33 Self association of the EPO mimetic Proteins are known to fold on a time scale ranging from ms to seconds or even
 

Summary:  13 Chapter 2 Self association of the EPO mimetic peptide 1 Proteins are known to fold on a time... their lowest free energy conformation. In this chapter, the self association of the EPO mimetic peptide 1... association of the EPO mimetic peptide 1 #12;2.1. ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
34 Choosing membrane mimetics for NMR structural studies of transmembrane proteins Dror E. Warschawski a,b,
 

Summary:  Review Choosing membrane mimetics for NMR structural studies of transmembrane proteins Dror E... March 2011 Available online 6 April 2011 Keywords: Membrane protein NMR Membrane mimetics Detergents... studies, an incredibly large number of membrane mimetics options are available. This review provides

  

Source: Institut de Biologie Physico-Chimique CNRS, Physico-Chimie Moléculaire des Membranes Biologiques

 

Collection: Chemistry ; Biology and Medicine

 
35 Inhibition of HIV-1 virus replication using small soluble Tat peptides Emmanuel Agbottah a
 

Summary:  Inhibition of HIV-1 virus replication using small soluble Tat peptides Emmanuel Agbottah... /44 peptide from the core domain can inhibit HIV-1 gene expression and replication. The peptides are not toxic... the Cdk2 X-ray crystallography structure, we found that the low-energy wild-type peptides could bind

  

Source: Zeng, Chen - Department of Physics, George Washington University

 

Collection: Physics

 
36 Roles of Arginine and Lysine Residues in the Translocation of a Cell-Penetrating Peptide F Solid-State NMR
 

Summary:  19 F-19 F distances of 6.0, 9.7, and 10 A° , I5R-Q8 and I5R-K13R distances of <6.0 A° , RN... in an Elastin-Mimetic Peptide (VPGVG)3 Investigated by Solid-State NMR. J. Am. Chem. Soc. 126, 4199­4210. 46... Roles of Arginine and Lysine Residues in the Translocation of a Cell-Penetrating ...

  

Source: Hong, Mei - Department of Chemistry, Iowa State University

 

Collection: Chemistry

 
37 High Affinity Ligand Binding by Integrins Does Not Involve Head Separation*
 

Summary:  dissociated wild type IIb 3 on the cell surface, a ligand-mimetic Arg-Gly-Asp peptide did not, as judged... subunit. A crystal structure with a bound ligand-mimetic peptide revealed that ligand binds... Head Separa- tion--We used the AP2 and 10E5 mAbs to determine whether RGD-mimetic ...

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
38 BioMed Central Page 1 of 14
 

Summary:  , a BLV LHR-mimetic peptide antagonized BLV envelope-mediated membrane fusion but failed to inhibit HTLV-1... are inhibitory to envelope-mediated mem- brane fusion. Prototypic -helical TM-mimetic inhibitory peptides have... interaction of the HTLV-1 LHR-mimetic ...

  

Source: van Aalten, Daan - Division of Biological Chemistry and Molecular Microbiology, University of Dundee

 

Collection: Biology and Medicine

 
39 Kinetics and Substrate Specificity of Membrane-reconstituted Peptide Transporter DtpT of Lactococcus lactis
 

Summary:  peptides or peptide mimetics. The DtpT protein appears to be specific for di- and tripeptides... of the peptide backbone, as well as for peptide mimetics. MATERIALS AND METHODS Material. All peptides were... of the peptide ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
40 Therapeutic Index of Gramicidin S is Strongly Modulated by D-Phenylalanine Analogues at the Concepcion Solanas,
 

Summary:  Ved July 17, 2008 Analogues of the cationic antimicrobial peptide gramicidin S (GS), cyclo... the development of new antimicrobial chemotherapy approaches. A number of peptides with antimicrobial activity... multidrug resistant bacteria. An attractive feature of these peptides is that, by acting mostly through

  

Source: Pompeu Fabra, Universitat - Departament de Ciències Experimentals i de la Salut, Proteomics and Protein Chemistry Unit

 

Collection: Biotechnology


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41 WCBSURC 2007 Poster Sessions Poster Session I Odd-numbered posters, 11:35am 12:35pm
 

Summary:  TO APOLIPOPROTEIN A-I MIMETIC PEPTIDES. Garrett Perrin* (Mohamad Navab, Greg Hough), University of California, Los... ., Long Beach, CA 90840. P29. APOA-1 MIMETIC PEPTIDE D-4F INCREASES PARAOXONASE ACTIVITY. Dien Tran* (Greg... Rockville Pike, Bethesda, MD 20892. #12;18 P36. APOA-1 ...

  

Source: Dahlquist, Kam D. - Biology Department, Loyola Marymount University

 

Collection: Biology and Medicine

 
42 Production and Utilization of Peptides in Lactococcus lactis
 

Summary:  for the binding protein DppA: (i) a high affinity for di- and tripeptides; (ii) a requirement for a free N... Production and Utilization of Peptides in Lactococcus lactis #12;II To my mother, Jianjun LI (1933... -1983). Cover: Production and utilization of peptides in Lactococcus lactis Cover design: Gang FANG ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
43 Structure and Function of Integral Membrane Protein
 

Summary:  Structure and Function of Integral Membrane Protein Domains Resolved by Peptide... September 2002; accepted 19 December 2002 Abstract: We have used synthetic lipidated peptides ("peptide... -fluorenylmethyl- oxycarbonyl (Fmoc) solid-phase peptide synthesis to prepare full-length phospholamban (PLB1

  

Source: Thomas, David D. - Departments of Biochemistry, Molecular Biology, & Biophysics, University of Minnesota

 

Collection: Biology and Medicine

 
44 Interaction of a two-transmembrane-helix peptide with lipid bilayers and dodecyl sulfate micelles
 

Summary:  simulations of phospholipids, J Phys Chem B, 104 (2000) 7510-7515. [32] K.V. Pervushin, V. Orekhov, A.I. Popov... 1 Interaction of a two-transmembrane-helix peptide with lipid bilayers and dodecyl sulfate micelles... the peptide was transferred to SDS. MD simulation showed no evidence for significant disruption of helix

  

Source: Chen, Liao Y. - Department of Physics and Astronomy, University of Texas at San Antonio

 

Collection: Physics

 
45 Project Title: Metathesis in biological systems.
 

Summary:  of nature's amino acids, peptides, and bioconjugate in solution and on surfaces (see below). The ability... extended to cross metathesis dimerization to provide access to disufide bond mimetics, the makeup

  

Source: Australian National University, Centre for Antimatter-Matter Studies

 

Collection: Physics

 
46 Supporting Information Immobilization of the Influenza A M2 Transmembrane Peptide in Virus-
 

Summary:  1 Supporting Information Immobilization of the Influenza A M2 Transmembrane Peptide in Virus... - Envelope Mimetic Lipid Membranes: A Solid-State NMR Investigation Wenbin Luo, Sarah D. Cady, and Mei Hong

  

Source: Hong, Mei - Department of Chemistry, Iowa State University

 

Collection: Chemistry

 
47 Biomaterials 26 (2005) 46954706 Viscoelastic and mechanical behavior of recombinant
 

Summary:  were liberated from the respective plasmids via restriction digestion with BspM I and SexA I... , respectively, of the diblock poly- mer P2 (Scheme 1). Restriction cleavage of each plasmid with SexA I and Xma... pP2 was propagated in E. coli strain SCS110 and cleaved with restriction endonuclease ...

  

Source: Srinivasarao, Mohan - School of Polymer, Textile and Fiber Engineering, Georgia Institute of Technology

 

Collection: Materials Science

 
48 Determinants of Activity in the Erythropoietin Receptor Studied with
 

Summary:  identified by Seubert et al. are shown in Figure 6.2B. 1.4 EPO mimetic peptides (EMPs) With regards to its... from reference [38](EPO) and from reference [18](EPO mimetic peptides). b) ED50 is the concentration... reference [38](EPO) and from reference [18](EPO mimetic ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
49 ADVANCEMENT IN PROTEIN INFERENCE FROM SHOTGUN PROTEOMICS USING PEPTIDE DETECTABILITY
 

Summary:  . Nesvizhskii, A. I., Keller, A., Kolker, E. & Aebersold, R. (2003). A statistical model for identifying... proteins by tandem mass spectrometry. Anal Chem 75, 4646-4658. . 7. Nesvizhskii, A. I. & Aebersold, R... ADVANCEMENT IN PROTEIN INFERENCE FROM SHOTGUN PROTEOMICS USING ...

  

Source: Radivojac, Predrag - School of Informatics, Indiana University

 

Collection: Computer Technologies and Information Sciences

 
50 BioMed Central Page 1 of 10
 

Summary:  - yunwlam@cityu.edu.hk; Angus I Lamond - a.i.lamond@lifesci.dundee.ac.uk * Corresponding author Abstract... provide sufficient interaction specificity which may allow the development of drugs or peptide mimetics... referred to as the RVXF/W motif. Results: We demonstrate that a peptide based on the RVXF/W ...

  

Source: Trinkle-Mulcahy, Laura - Department of Cellular and Molecular Medicine, University of Ottawa

 

Collection: Biology and Medicine

 
51 PRINCIPLES OF MIMETIC DISCRETIZATIONS OF DIFFERENTIAL OPERATORS
 

Summary:  . The isomorphism J : Ck Ck is given by Ja = i a, i k i k . (3.6) We identify i k with its dual so that i k, j k... = (Wi 12)T and a1 b2 = m3 i=1 (aT Wi 12b)i 3 and b2 a1 = m3 i=1 (bT (Wi 12)T a)i 3 . (5.2) Matrix... of the left hand side in (4.23) is a D a = a D a, m3 i=1 i 3 = m3 i=1 aT Wi 12( D a) ...

  

Source: Bochev, Pavel - Applied Mathematics and Scientific Computing Department, Sandia National Laboratories

 

Collection: Mathematics

 
52 Molecules 2011, 16, 1426-1451; doi:10.3390/molecules16021426 ISSN 1420-3049
 

Summary:  .mdpi.com/journal/molecules Review Material Binding Peptides for Nanotechnology Urartu Ozgur Safak Seker 1,2, * and Hilmi Volkan... peptides and their utilization in nanotechnology, which has brought new challenges and opportunities... and peptides. This combinatorial approach has also been adapted over the past decade to select ...

  

Source: Gürel, Levent - Department of Electrical and Electronics Engineering, Bilkent University

 

Collection: Engineering

 
53 Polar residues in transmembrane helices can decrease electrophoretic mobility in polyacrylamide gels without causing helix dimerization
 

Summary:  and assembly of membrane proteins using peptides and SDS-PAGE experiments as a membrane mimetic system... and rapidly on the oligomeric state of a peptide in a "membrane mimetic" environment, SDS-PAGE is still often... interactions between peptides in SDS solution. Here we offer a ...

  

Source: Wimley, William C. - Department of Biochemistry, Tulane University

 

Collection: Biology and Medicine

 
54 PRINCIPLES OF MIMETIC DISCRETIZATIONS OF DIFFERENTIAL OPERATORS PAVEL B. BOCHEV1 AND JAMES M. HYMAN2
 

Summary:  . The isomorphism J : Ck Ck is given by Ja = i a, i k i k .(3.6) We identify i k with its dual so that i k, j k... = (Wi 12)T and a1 b2 = m3 i=1 (aT Wi 12b)i 3 and b2 a1 = m3 i=1 (bT (Wi 12)T a)i 3 .(5.2) Matrix... of the left hand side in (4.23) is a D a = a D a, m3 i=1 i 3 = m3 i=1 aT Wi 12( D a) ...

  

Source: Hyman, James "Mac" - Theoretical Division, Los Alamos National Laboratory

 

Collection: Mathematics

 
55 Expanding the polypeptide backbone: hydrogen-bonded conformations in hybrid
 

Summary:  . An extraordinary wealth of conformational information is now available on peptides and proteins, which are formed... of peptides constructed from higher homologues (u) of a-amino acids. This review examines the nature... of intramolecularly hydrogen-bonded conformations of hybrid peptides formed by amino acid residues, with a ...

  

Source: Balaram , P. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
56 The International Journal of Biochemistry & Cell Biology 39 (2007) 23142323 Peptides derived from type I thrombospondin repeat-containing
 

Summary:  novel peptides with anti-angiogenic activity, and designing mimetic peptides with tailored properties... can help us design novel synthetic peptides or peptide mimetics derived from these thrombospondin... ., Schneider, A. J., Davidson, D. J., Majest, S. M., et al. ...

  

Source: Popel, Aleksander S. - Department of Biomedical Engineering, Johns Hopkins University

 

Collection: Engineering ; Biology and Medicine

 
57 Empirical Evaluation of a Dynamic Experiment Design Method for Prediction of MHC Class I-Binding Peptides1
 

Summary:  -Binding Peptides1 Keiko Udaka,2 * Hiroshi Mamitsuka,3 Yukinobu Nakaseko,* and Naoki Abe The ability to predict MHC... -binding peptides remains limited despite ever expanding demands for specific immunotherapy against cancers... sequence patterns have been hampered by the insufficiency of the number/quality of the peptide binding ...

  

Source: Rosset, Saharon - IBM T.J. Watson Research Center

 

Collection: Mathematics

 
58 Research Article A Bayesian Approach to Protein Inference Problem
 

Summary:  graph (Fig. 1a), i.e., a bipartite graph in which two disjoint sets of vertices represent the proteins... of images. IEEE Trans. Pattern Analysis Mach. Intell. 6, 721­741. Keller, A., Nesvizhskii, A.I., Kolker, E... ­309. Nesvizhskii, A.I. 2007. Protein identification by tandem mass spectrometry and ...

  

Source: Radivojac, Predrag - School of Informatics, Indiana University

 

Collection: Computer Technologies and Information Sciences

 
59 Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain
 

Summary:  Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2... -phosphorus- containing macrocyclic peptide mimetic that exhibits significant anti- proliferative effects against erbB-2... to the protein. Here, we describe the structural basis for the binding of a macrocyclic ...

  

Source: Waugh, David S.- Macromolecular Crystallography Laboratory, National Cancer Institute; Wlodawer, Alexander - Macromolecular Crystallography Laboratory, National Cancer Institute

 

Collection: Biology and Medicine ; Chemistry

 
60 Phage Display Technologies Nicole Stricker, Johns Hopkins University, Baltimore, Maryland, USA
 

Summary:  virus (phage) as a vehicle to express diverse protein or peptide sequences as part of the phage coat... viral infection, the expressed peptides are displayed on the surface of the viral particle. Depending... on the DNA fragments cloned, phage display allows for expression of either short peptides or large proteins

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine


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61 Membrane-Bound Dimer Structure of a -Hairpin Antimicrobial Peptide from Rotational-Echo Double-Resonance Solid-State NMR
 

Summary:  curves for out-of-register NCCN hydrogen-bonding motifs. (a) (i, j - 2) parallel packing. (b) (i, j + 4... Membrane-Bound Dimer Structure of a -Hairpin Antimicrobial Peptide from Rotational-Echo Double... Vised Manuscript ReceiVed May 12, 2006 ABSTRACT: The intermolecular packing of a -hairpin antimicrobial ...

  

Source: Hong, Mei - Department of Chemistry, Iowa State University

 

Collection: Chemistry

 
62 Development of Novel Small-Size Peptides as Putative Therapeutic Drugs
 

Summary:  an adequate chemical modification. Since the number of peptides and peptide mimet- ics to choose from... #12;Development of Novel Small-Size Peptides as Putative Therapeutic Drugs m. f. Masman 2010 #12... groningen Development of novel small-size peptides as putative therapeutic drugs ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
63 Chemical shift assignment and structural plasticity of a HIV fusion peptide derivative in dodecylphosphocholine micelles
 

Summary:  - sphocholine (DPC) micelles. The micelles serve as a membrane mimetic with which membrane-associated peptides... , The helix­hinge­helix structural motif in human apolipoprotein A-I determined by NMR spectroscopy... Chemical shift assignment and structural plasticity of a HIV fusion peptide derivative

  

Source: Weliky, David - Department of Chemistry, Michigan State University

 

Collection: Chemistry

 
64 The Application of Molecular Dynamics Simulation Techniques and Free Energy
 

Summary:  mimetic peptide 1 13 2.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . 15 2.2 Methods... mimetic peptide 1 . . 21 2.3.2 Dimerization of the EPO mimetic peptide 1 . . 22 2.3.3 Conformational space... -dependant kinase CKS cyclin-dependant kinase subunit ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
65 Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain
 

Summary:  by phosphothreonine mimetic peptides was sufficient to induce mitotic arrest and apoptotic cell death. The mode... ). To examine the effect of the Pmab-containing mimetic peptide in vivo, and to overcome poor membrane... -Pmab peptide, another type of 2-amino-4,4-difluoro-3-methyl- ...

  

Source: Wlodawer, Alexander - Macromolecular Crystallography Laboratory, National Cancer Institute

 

Collection: Chemistry ; Biology and Medicine

 
66 ISSN 1744-683X 1744-683X(2010)6:20;1-Q
 

Summary:  | Pages 4951­5226 PAPER E. Kokkoli et al. Fibronectin-mimetic peptide- amphiphile nanofiber gels support... : a mechanically robust tissue engineering scaffold Tissue Engineering #12;Fibronectin-mimetic peptide... -amphiphile nanofibers as a potential scaffold for tissue engineering. A ...

  

Source: Kokkoli, Efie - Department of Chemical Engineering and Materials Science, University of Minnesota

 

Collection: Materials Science

 
67 J. Phys. II Yance 5 (1995) 1427-1431 OCTOBER 1995, PAGE 1427 Classification
 

Summary:  2 + d2)x(BK~/8a)~/~I(ro/I) with I(z) = z[kei(z)ker'(z)-ker(z)kei'(z)]. The constants of integration... Peptides Huey W. Huang Physics Department, Rice University, Houston, Texas 77251-1892, U-S-A- (Received15... peptides exhibit an insertion transition when they interact with lipid bilayers. At low concentrations

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
68 A Hydrogen Bond Surrogate Approach for Stabilization of Short Peptide Sequences in r-
 

Summary:  efforts include -peptide helices, terphenyl helix mimetics, miniproteins, peptoid helices, and side... .; Hamilton, A. D. Synthetic non-peptide mimetics of alpha- helices. Chem. Soc. Rev. 2007, 36, 326­334. 10... Garner, J.; Harding, M. M. Design and synthesis of R-helical peptides and ...

  

Source: Lawson, Catherine L. - Department of Chemistry and Chemical Biology, Rutgers University

 

Collection: Biology and Medicine ; Chemistry

 
69 Design of a Novel Fibronectin-Mimetic Peptide-Amphiphile for Functionalized Biomaterials
 

Summary:  Design of a Novel Fibronectin-Mimetic Peptide-Amphiphile for Functionalized Biomaterials Anastasia... fibronectin- mimetic peptides to target the integrin. However, to date, the therapeutic use of these peptides... performed on different days). NoVel ...

  

Source: Kokkoli, Efie - Department of Chemical Engineering and Materials Science, University of Minnesota

 

Collection: Materials Science

 
70 The Importance of Peptide Detectability for Protein Identification, Quantification, and Experiment Design in MS/MS Proteomics
 

Summary:  The Importance of Peptide Detectability for Protein Identification, Quantification, and Experiment... States Received June 5, 2010 Peptide detectability is defined as the probability that a peptide... and label-free quantification. Previously, predictors for peptide detectability trained on standard

  

Source: Radivojac, Predrag - School of Informatics, Indiana University

 

Collection: Computer Technologies and Information Sciences

 
71 Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers
 

Summary:  ) Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273: 458­464. 13. Desai... Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers... . With peptide structure information and the NMR structure of CRIP1, the higher-affinity A1 ...

  

Source: Dokholyan, Nikolay V. - Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill

 

Collection: Physics ; Biology and Medicine

 
72 Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides
 

Summary:  .T.D., A.I., and D.G. analyzed data; and N.P.C., J.A.P., A.M.C., M.T.D., and A.E.B. wrote the paper... Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides... August 31, 2007) Antimicrobial peptides (AMPs) and their mimics are emerging as promising antibiotic

  

Source: Barron, Annelise E. - Department of Bioengineering, Stanford University

 

Collection: Materials Science ; Biotechnology

 
73 Isolation of peptides of the brevinin-1 family with potent
 

Summary:  Rana boylii 210 J. Peptide Res. 62, 2003 / 207­213 #12;membrane-mimetic environment (26). As shown... Isolation of peptides of the brevinin-1 family with potent candidacidal activity from the skin... types of antifungal agents. Six peptides with antimicrobial activity were isolated from norepinephrine

  

Source: Davidson, Carlos - Environmental Studies Program, San Francisco State University

 

Collection: Environmental Sciences and Ecology

 
74 PAPER www.rsc.org/obc | Organic & Biomolecular Chemistry Structural studies of model peptides containing b-, c-and d-amino acids
 

Summary:  PAPER www.rsc.org/obc | Organic & Biomolecular Chemistry Structural studies of model peptides... structures of five model peptides Piv-Pro-Gly-NHMe (1), Piv-Pro-bGly-NHMe (2), Piv-Pro-bGly-OMe (3), Piv... of the structures of peptides 1 and 2 illustrates the dramatic consequences upon backbone homologation in short

  

Source: Balaram , P. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
75 Mechanism of Penetration of Antp(43-58) into Membrane Bilayers Wenyi Zhang and Steven O. Smith*
 

Summary:  : Antp(43-58) is one of many peptides with basic and aromatic residues capable of crossing cell membranes... efficiently in a receptor-independent manner. The basic-aromatic motif is responsible for peptide binding... . We use high-resolution 1H solution NMR methods to establish the location of the Antp(43-58) peptide

  

Source: Smith, Steven O.- Department of Biochemistry and Cell Biology, SUNY at Stony Brook

 

Collection: Biology and Medicine

 
76 Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response
 

Summary:  .1016/j.cell.2009.05.021 SUMMARY Smac mimetics induce apoptosis synergistically with TNF-a by triggering... ., 2004). Our study revealed that the Smac mimetic together with TNF-a, promote the formation of a caspase... ., 2008). During these studies, we noticed that the Smac mimetic-induced cell death in human colon cancer

  

Source: National Institute of Biological Sciences, Beijing

 

Collection: Biology and Medicine

 
77 Multiple Role of Di-tripeptide Transport Protein DtpT in Proteolytic System of Lactococcus lactis
 

Summary:  , is reported to be an inhibitor of the peptide transporter PepT1; some peptides or peptide mimetics... number of oligopeptides ranging from 4 to 30 amino acid residues. Part of the released peptides are taken... up by the cells via the oligopeptide transport system, and these ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
78 Conformational properties of hybrid peptides containing
 

Summary:  Conformational properties of hybrid peptides containing a- and x-amino acids* R.S. Roy P. Balaram... : 91 80 23600683/91 80 23600535 E-mail: pb@mbu.iisc.ernet.in Key words: ax sequences; b-peptides; c-peptides... ; hybrid peptides; peptide conformations Abstract: This review briefly surveys ...

  

Source: Balaram , P. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
79 Combinatorial Libraries of Synthetic Peptides as a Model for Shotgun Proteomics
 

Summary:  A, respectively. NTMILEICTR from complement com- ponent C3 and ATEHLSTLSEK from apolipoprotein A-I... Combinatorial Libraries of Synthetic Peptides as a Model for Shotgun Proteomics Brian C. Bohrer... the analytical complexity of biological proteolytic digests has been developed. Combinatorial peptide libraries

  

Source: Radivojac, Predrag - School of Informatics, Indiana University

 

Collection: Computer Technologies and Information Sciences

 
80 Leading Edge Cell 131, November 16, 2007 2007 Elsevier Inc. 655
 

Summary:  -molecule mimetics interact with the BIR domain of IAPs. Because XIAP is a bona de caspase inhibitor, it was presumed... that Smac mimetics primarily target XIAP thus allowing activation of caspase-9, result- ing... , to participate in TNF-induced NF-B activation (Rothe et al., 1995). The goal has been to use Smac mimetics

  

Source: Wu, Hao - Department of Biochemistry, Cornell University

 

Collection: Biology and Medicine


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81 Published: December 22, 2010 r 2010 American Chemical Society 790 dx.doi.org/10.1021/ac102272r |Anal. Chem. 2011, 83, 790796
 

Summary:  ), 113­122. (9) Searle, B. C.; Turner, M.; Nesvizhskii, A. I. J. Proteome Res. 2008, 7 (1), 245­253. (10... .; Biemann, K Anal. Chem. 1971, 43 (6), 681­691. (18) Ausloos, P.; Clifton, C. L.; Lias, S. G.; Mikaya, A. I... . M. Proteins 2010, 78 (2), 365­380. (45) Keller, A.; Nesvizhskii, ...

  

Source: Radivojac, Predrag - School of Informatics, Indiana University

 

Collection: Computer Technologies and Information Sciences

 
82 Structure and mechanism of b-hairpin antimicrobial peptides in lipid bilayers from solid-state NMR spectroscopy
 

Summary:  of this representative b-hairpin antimicrobial peptide. We found that PG-1 structure is membrane dependent: in bacteria-mimetic... Structure and mechanism of b-hairpin antimicrobial peptides in lipid bilayers from solid-state NMR... , and dynamics of the arginine-rich b-hairpin antimicrobial peptide PG-1 as ...

  

Source: Hong, Mei - Department of Chemistry, Iowa State University

 

Collection: Chemistry

 
83 Host-defense peptides isolated from the skin secretions of the Northern red-legged frog Rana aurora aurora
 

Summary:  Host-defense peptides isolated from the skin secretions of the Northern red-legged frog Rana aurora... , Novo Nordisk A/S, 2880 Bagsvaerd, Denmark e European Institute for Peptide Research (IFRMP 23... ; accepted 4 May 2004 Available online 15 June 2004 Abstract Antimicrobial peptides in the skin secretions

  

Source: Davidson, Carlos - Environmental Studies Program, San Francisco State University

 

Collection: Environmental Sciences and Ecology

 
84 Amino Acid Residues in the IIb Subunit That Are Critical for Ligand Binding to Integrin IIb 3 Are Clustered in the
 

Summary:  -Ligand Interactions44278 #12;K164A, R165A, Y166A, V200A, I203A, F204A, Y207A, S222A, D224A, S226A, F231A... binding to these mAbs (e.g. D74A, L84A, F87A, W110A, H112A, W113A, R147A, I203A, and Y207A) (Table III... and ligand-mimetic antibodies (e.g. LJ- CP3), suggesting that these ...

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
85 Real-Time Surface Plasmon Resonance Imaging Measurements for the Multiplexed Determination
 

Summary:  .; Hallberg, A.; Samuelsson, B.; Danielson, U. H. J. Med. Chem. 2002, 45, 5430-5439. (9) Archakov, A. I... of Protein Adsorption/Desorption Kinetics and Surface Enzymatic Reactions on Peptide Microarrays Greta J... of five different peptides: N terminal and C terminal im- mobilized wild-type S ...

  

Source: Corn, Robert M.- Department of Chemistry, University of California, Irvine

 

Collection: Chemistry

 
86 Submitted to the Annals of Applied Statistics A NESTED MIXTURE MODEL FOR PROTEIN
 

Summary:  samples. In a typical experiment, proteins in a sample are first broken into their constituent peptides... . The resulting mixture of peptides is then subjected to mass spectrometry, which generates thousands of spectra... , each characteristic of its generat- ing peptide. Here we consider the problem of inferring, from

  

Source: Das, Soma - Department of Human Genetics, University of Chicago

 

Collection: Biology and Medicine

 
87 Membrane Thickening by the Antimicrobial Peptide PGLa Georg Pabst,* Stephan L. Grage,y
 

Summary:  . Liposome-based biomem- brane mimetic systems: implications for lipid-peptide interactions. In Advances... -substitution analog with membrane-mimetic systems. In Peptides: The Wave of the Future. R. A. Houghten and M. Lebl... -ray diffraction studies of the specificity of the interaction of antimicrobial ...

  

Source: Watts, Anthony - Biomembrane Structure Unit, Department of Biochemistry, University of Oxford

 

Collection: Biology and Medicine

 
88 Two Apolipoprotein E Mimetic Peptides, ApoE(130-149) and ApoE(141-155)2 Bind to LRP1
 

Summary:  Two Apolipoprotein E Mimetic Peptides, ApoE(130-149) and ApoE(141-155)2 , Bind to LRP1 Johnny E... for the two different apoE mimetic peptides (Table 2). The binding affinity (KD) was approximately 150 n... , S. V., and Laskowitz, D. T. (2001) Apolipoprotein E and Mimetic ...

  

Source: Komives, Elizabeth A. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Biology and Medicine

 
89 High-Throughput Method for Ranking the Affinity of Peptide Ligands Selected from Phage Display Libraries
 

Summary:  , W. J. (1996) Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273... ARTICLES High-Throughput Method for Ranking the Affinity of Peptide Ligands Selected from Phage... July 23, 2007; Revised Manuscript Received February 18, 2008 The use of phage display peptide libraries

  

Source: Hammock, Bruce D. - Department of Entomology, University of California, Davis

 

Collection: Biotechnology

 
90 J.S. Murray S.D.S. Jois
 

Summary:  recognize the A11-mer peptide, that has a truncated N-terminus (thus starts with A, Fig. 3A). I-As -derived... peptide on two class II major histocompatibility complex (MHC II) molecules predicts polarized T... -cell receptor (TCR) contact positions. J. Peptide Res., 2002, 59, 115±122. ...

  

Source: Schountz, Tony - Department of Biological Sciences, University of Northern Colorado

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
91 Bundles Consisting of Extended Transmembrane Segments of Vpu from HIV-1: Computer Simulations and Conductance Measurements
 

Summary:  the bundle with its N-terminal end during a 1 ns simulation (Figure 2A, I, left segment in the bundle... .4)° [corresponding ) (-52.0 ( 12.2)°] and causes the strong bend (see Figure 2A, I). The and values for the EYR... of the peptide, the cytoplasmic and transmembrane (TM) domains, ...

  

Source: Fischer, Wolfgang - Institute of Biophotonics, School of Biomedical Science and Engineering, National Yang-Ming University; Watts, Anthony - Biomembrane Structure Unit, Department of Biochemistry, University of Oxford

 

Collection: Biology and Medicine

 
92 Structure and dynamics of cationic membrane peptides and proteins: Insights
 

Summary:  REVIEW Structure and dynamics of cationic membrane peptides and proteins: Insights from solid... February 2011 proteinscience.org Abstract: Many membrane peptides and protein domains contain functionally... the membrane-bound topology of these peptides. A versatile array of solid-state NMR experiments now readily

  

Source: Hong, Mei - Department of Chemistry, Iowa State University

 

Collection: Chemistry

 
93 Mass Spectrometric Protein Identification Using the Global Proteome Machine
 

Summary:  data in a relational database, Proteomics, 2, 36­47. 22. A. Keller, A.I. Nesvizhskii, E. Kolker, and R... sequence collection searching with masses of peptides or their fragments, spectral library searching... spectra that correspond to peptides and their fragments. It is important to find all the relevant peaks

  

Source: Chait, Brian T. - Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University

 

Collection: Biology and Medicine

 
94 The ascaphins: a family of antimicrobial peptides from the skin secretions of the most primitive extant frog, Ascaphus truei
 

Summary:  The ascaphins: a family of antimicrobial peptides from the skin secretions of the most primitive... and is regarded as the sister taxon to the clade of all other living frogs. Eight structurally related peptides... families of antimicrobial peptides from frog skin but display limited sequence identity with the cationic

  

Source: Davidson, Carlos - Environmental Studies Program, San Francisco State University

 

Collection: Environmental Sciences and Ecology

 
95 Molecules 2011, 16, 3499-3518; doi:10.3390/molecules16053499 ISSN 1420-3049
 

Summary:  .mdpi.com/journal/molecules Review Phage Display of Combinatorial Peptide Libraries: Application to Antiviral Research Guillaume... . In this context, antiviral peptides constitute a promising area for disease prevention and treatment... . The identification and development of these inhibitory peptides require the high-throughput ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
96 Effects of arginine density on the membrane-bound structure of a cationic antimicrobial peptide from solid-state NMR
 

Summary:  Effects of arginine density on the membrane-bound structure of a cationic antimicrobial peptide... November 2008 Keywords: Antimicrobial peptide Depth of insertion Oligomeric structure Arginine Solid... structure of a cationic -hairpin antimicrobial peptide in which the number of Arg residues has been halved

  

Source: Hong, Mei - Department of Chemistry, Iowa State University

 

Collection: Chemistry

 
97 Phage display screening against a set of targets to establish peptide-based sugar mimetics and molecular docking to predict binding site
 

Summary:  Phage display screening against a set of targets to establish peptide-based sugar mimetics... . Docking studies were conducted to establish whether the mimetic peptides bind to the lectin Con... the question as to whether some of these peptides are indeed true sugar ...

  

Source: Orner, Brendan Patrick - Division of Chemistry and Biological Chemistry, Nanyang Technological University

 

Collection: Biology and Medicine ; Chemistry

 
98 Available online at www.sciencedirect.com De novo designed synthetic mimics of antimicrobial peptides
 

Summary:  and products [53,54]. Design of arylamide and heteroarylamide antimicrobial peptide mimetics The goal of our... peptides Richard W Scott1 , William F DeGrado2 and Gregory N Tew3 Antimicrobial peptides are small cationic... to accomplish this goal with peptide-based structures. Although ...

  

Source: Tew, Gregory N. - Department of Polymer Science and Engineering, University of Massachusetts at Amherst

 

Collection: Materials Science ; Chemistry

 
99 Peptide 15-mers of defined sequence that substitute for random amino acid copolymers in amelioration
 

Summary:  of the copolymers might be enhanced by the peptide mimetics. In this paper we report generation of three peptide... Peptide 15-mers of defined sequence that substitute for random amino acid copolymers... with MBP 85­99 for binding. Moreover, two high-affinity synthetic peptide 15-mers ...

  

Source: Strominger, Jack L. - Department of Molecular and Cellular Biology, Harvard University

 

Collection: Biology and Medicine

 
100 A Bayesian Approach to Protein Inference Problem in Shotgun Proteomics
 

Summary:  - uration graph (Fig. 1(a)), i.e. a bipartite graph in which two disjoint sets of vertices represent... algorithms identify proteins?. Nat. Biotechnol. 25(7), 755­757 (2007) 6. Nesvizhskii, A.I.: Protein... ­1467 (2004) 10. Nesvizhskii, A.I., Aebersold, R.: Interpretation of shotgun proteomic data: the ...

  

Source: Radivojac, Predrag - School of Informatics, Indiana University

 

Collection: Computer Technologies and Information Sciences


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