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Sample search results for: a-induced liver injury

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1 Diverse Roles of Invariant Natural Killer T Cells in Liver Injury and Fibrosis Induced by Carbon Tetrachloride
 

Summary:  J 18 / mice are resistant to concanavalin A-induced and -GalCer­induced acute liver injury... Diverse Roles of Invariant Natural Killer T Cells in Liver Injury and Fibrosis Induced by Carbon... Liver fibrosis is a common scarring response to all forms of chronic ...

  

Source: Lian, Zhe-Xiong - School of Life Sciences, University of Science and Technology of China

 

Collection: Biology and Medicine

 
2 Overexpression of the gene for transmembrane 4 superfamily member 4 accelerates liver damage in rats treated with CCl4
 

Summary:  the role of TM4SF4 during liver injury. Methods:Expression of TM4SF4 was analyzed by RT-PCR and Western... was achieved by injection of sense or antisense TM4SF4 expression plasmids. Assessment of liver injury... - erating liver injury, which may be mediated by the ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
3 Liver fibrosis is the progressive accumulation of connective tissue in the liver, which can be caused by chronic liver injury of various etiologies. The most common causes of
 

Summary:  in the liver, which can be caused by chronic liver injury of various etiologies. The most common causes... fibrogenic cells and the production of excess extracellular matrix. In addition, liver injury leads... and inflammation depends on the type and duration of the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
4 Development of a chemical liver injury model in zebrafish (Danio rerio) Wolfram Goessling*, Trista E. North*, Gerhard Weber and Leonard I. Zon
 

Summary:  Development of a chemical liver injury model in zebrafish (Danio rerio) Wolfram Goessling*, Trista... of liver regeneration after hepatic injury is a well established method for the identification of genetic... models of liver regrowth in each injury setting. We have ...

  

Source: Harvard University, North and Goessling Labs

 

Collection: Biology and Medicine

 
5 Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids
 

Summary:  -IFN- mono- clonal antibodies (mAbs) protect mice from ConA-induced liver injury (Gantner et al., 1995; Ku... ameliorates ConA-induced T-cell-mediated liver injury by up-regulating Forkhead helix transcription factor p3... significant. Results THC Ameliorates ...

  

Source: Cravatt, Benjamin - Department of Cell Biology, Scripps Research Institute

 

Collection: Biology and Medicine

 
6 H.Rachmawati1 , L.Beljaars1
 

Summary:  of antifibrotic drugs via M6P/IGF-II receptor. Upregulation of this receptor during liver injury on HSC, the most... of markers reflecting liver injury and cholestasis in fibrotic rats one week (BDL-1), and in BDL-1 rats... response to tissue injury, J Biol Chem. 2000, 275(4):2247-50. 2. ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
7 Treatment of liver ischemia reperfusion injury by limiting
 

Summary:  Treatment of liver ischemia­ reperfusion injury by limiting thrombospondin-1/CD47 signaling Jeff S... underwent liver I/R injury. Wild-type animals were pretreated with CD47 or control antibodies before liver I... assessed. Results. TSP1-null and CD47-null mice subjected to subtotal ...

  

Source: Frazier, William A. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis

 

Collection: Biology and Medicine

 
8 TOXICOLOGICAL SCIENCES 80, 203213 (2004) DOI: 10.1093/toxsci/kfh146
 

Summary:  idiosyncratic-like liver injury from the his- tamine 2-receptor antagonist, ranitidine (RAN). Coadministration... vehicle-, LPS-, RAN- and LPS/RAN-treated rats before the onset of significant liver injury in the LPS... , and liver samples were taken for evaluation of ...

  

Source: Zacharewski, Timothy R. - Department of Biochemistry and Molecular Biology, Michigan State University

 

Collection: Biology and Medicine

 
9 SCOPE OF THE THESIS Liver fibrosis is characterized by the accumulation of excessive amounts of
 

Summary:  of excessive amounts of scar tissue in response to chronic liver injury. Important causes of chronic liver... of the liver parenchyma after massive hepatocyte injury. Because of these serious adverse effects, the use... 1 SCOPE OF THE THESIS #12;Chapter 1 10 Liver ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
10 mice express higher levels of several key molecules in the Akt signaling pathway, including phosphorylated PTEN (upstream
 

Summary:  after Jo2 treatment. Conclusion: Hepa- tocyte COX-2 protected against Fas-induced liver injury by acti... administration of AOM, a potent carcinogen, leads to chronic liver injury that is more severe in mice... at 20 wks. Body weights were measured weekly. Liver weights were measured at ...

  

Source: Max-Planck-Institut für biologische Kybernetik

 

Collection: Biology and Medicine

 
11 RESEARCH Open Access Tissue inhibitor of metalloproteinase 1 (TIMP-1)
 

Summary:  tetrachloride- induced liver injury and fibrosis in mice: involvement of hepatocyte STAT3 in TIMP-1 production... liver injury and repair; while the effect of TIMP-1 on hepatocellular damage remains obscure. Results... : Hepatic expression of TIMP-1 mRNA and protein was up-regulated both in acute and chronic ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
12 Donor-Derived, Liver-Specific Protein Expression after Bone Marrow Transplantation
 

Summary:  after BMT and determine whether the process is inducible with liver injury. Methods. Mice transgenic... . Adenoviral transduction of modified urokinase plasminogen activator (Ad-muPA) was used to induce liver injury... and persist after BMT. Ex- pression is low, but inducible with liver ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
13 Recently, precision-cut liver slices came into notice as a potential model for the study of stellate cell activation and liver fibrosis because, unlike current in vitro models, they
 

Summary:  system and bone marrow derived cells play a role in the response of the liver to injury. Firstly, injury... composition of this cellular infiltrate may vary with the type and stage of liver injury [28]. The recruitment... the response of the liver cells. Secondly, ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
14 M. van de Bovenkamp G.M.M. Groothuis
 

Summary:  Chapter 3 M. van de Bovenkamp G.M.M. Groothuis D.K.F. Meijer M.J.H.Slooff P. Olinga Human liver... in wound healing as well as in fibrosis development in the liver. Previously we developed a technique... to induce HSC activation in slices from rat liver. Although this model provides a physiologic, multicellular

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
15 Kupffer Cells Hasten Resolution of Liver Immunopathology in Mouse Models of Viral Hepatitis
 

Summary:  to liver injury during viral hepatitis due to their pro- inflammatory activity. Herein we utilized... ) pathogenesis considers these cells as important contributors to liver injury [4,5]. As the host tropism of HBV... , are considered important contributors to liver ...

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
16 PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish
 

Summary:  ) that function to restore GSH levels. Compounds that support liver recovery from APAP injury rather than... and elevate serum alanine aminotransferase (ALT) levels. Survival and histological evidence of liver injury... , a known reg- ulator of liver regeneration, after APAP ...

  

Source: Harvard University, North and Goessling Labs

 

Collection: Biology and Medicine

 
17 Cryopreservation of rat and monkey liver slices
 

Summary:  Cryopreservation of rat and monkey liver slices Ruben de Kanter Henk Koster Solvay Pharmaceuticals... A method for the long-term storage of liver slices by cryopreservation was developed. The viability... of liver slices was determined by analyzing the leakage of alanine aminotransferase, urea production

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
18 University of St Andrews -School of Medicine Handbook dcm10 13/06/2011 1 04_02_08
 

Summary:  potential BBV injuries: a Clinical Placement b Outwith training 1 Hepatitis B. Causes Hepatitis, liver... Virus Injury. An injury where an individual has been exposed to blood, body fluids or tissues via... percutaneous injury or spillages or splashing onto mucous membranes or existing ...

  

Source: Dholakia, Kishan - School of Physics and Astronomy, University of St Andrews

 

Collection: Physics

 
19 R e v i e w s MOLECULARMEDICINETODAY,MARCH1997 Liver regeneration: prospects
 

Summary:  proliferation dur- ing liver injury. Oval cells are thought to be derived from liver stem-cells. These stem... . However, large numbers of oval cells appear in the liver after severe liver injury. The rat had been fed... injury and ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
20 Marja van de Bovenkamp Liver fibrosis in vitro
 

Summary:  is the progressive accumulation of connective tissue in the liver, which can be caused by chronic liver injury... on the type of liver injury and the time after injury. In addition, besides activation of hepatic stellate... cells and/or other fibrogenic cells, ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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21 Natural Killer T Cells Exacerbate Liver Injury in a Transforming Growth Factor Receptor II Dominant-
 

Summary:  factor (TNF- ).17-19 Depletion of NKT cells ameliorates concanavalin A­induced liver disease,19 and CD1d... for concanavalin A-induced hepatic injury in mice. J Immunol 1997;159:1537-1542. 20. Oertelt S, Lian ZX, Cheng CM... Natural Killer T Cells Exacerbate Liver ...

  

Source: Lian, Zhe-Xiong - School of Life Sciences, University of Science and Technology of China

 

Collection: Biology and Medicine

 
22 Multiple Adaptive Mechanisms to Chronic Liver Disease Revealed at Early Stages of Liver Carcinogenesis
 

Summary:  induced in the early stages of hepatic disease, which protect the liver from injury, could have an effect... , Ribeiro FP, Souza GM, Campa A. Serum amyloid A-induced mRNA expression and release of tumor necrosis... Multiple Adaptive Mechanisms to Chronic Liver Disease Revealed at Early Stages of ...

  

Source: Domany, Eytan - Physics of Complex Systems, Weizmann Institute of Science

 

Collection: Biology and Medicine ; Physics

 
23 The cost-effectiveness of non-invasive liver tests for the detection of liver fibrosis in patients with suspected alcohol-related liver disease
 

Summary:  in the Western world. Alcohol produces a spectrum of liver injury which includes fatty liver, alcoholic hepatitis... , confirmation of a diagnosis of ALD; second, accurate staging of the degree of liver injury and third, exclusion... of these difficulties, interest has arisen in the use ...

  

Source: Oakley, Jeremy - Department of Probability and Statistics, University of Sheffield

 

Collection: Mathematics

 
24 Chapter -1 Aim of the thesis
 

Summary:  is a major matrix-producing cell during liver injury and enhanced extracellular matrix deposition... with recombinant IL-10 to treat chronic diseases in various tissues including the kidney and the liver. However... of cytokines as therapeutic agents. This is also true for IL-10 whose therapeutic application during ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
25 Subcellular Site of Superoxide Dismutase Expression Differentially Controls AP-1 Activity and Injury in Mouse Liver Following
 

Summary:  and Injury in Mouse Liver Following Ischemia/Reperfusion WEIHONG ZHOU,1 YULONG ZHANG,1 MICAELA S. HOSCH,1... production following warm I/R injury in the liver has demonstrated great promise in reducing acute hep... activation following I/R injury to the livers of ...

  

Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa

 

Collection: Biology and Medicine

 
26 NKG2A Inhibits Invariant NKT Cell Activation in Hepatic Toshihiko Kawamura,2
 

Summary:  § Activation of invariant NKT (iNKT) cells in the liver is generally regarded as the critical step for Con A-induced... independent experiments. FIGURE 3. Augmentation of Con A-induced hepatic injury in NKG2A signal-blocked gld... Aggravation of hepatic injury following blockade of the ...

  

Source: Raulet, David - Department of Molecular and Cell Biology, University of California at Berkeley

 

Collection: Biology and Medicine

 
27 Gliotoxin non-selectively induces apoptosis in fibrotic and normal livers
 

Summary:  (2):232-239 Chapter 3 #12;Chapter 3 36 Liver fibrosis is the common response to chronic liver injury, ultimately... in liver slices 37 INTRODUCTION Chronic liver injury leading to liver fibrosis can occur in response... of ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
28 Liver 2001: 21: 3744 Copyright C Munksgaard 2001 Printed in Denmark . All rights reserved
 

Summary:  with this lobar I/R model, which excludes any systemic influence on the extent of the liver injury. I/R caused... indicator of ischemia-reper- fusion liver injury. Hepatology 1992; 15: 432­7. 5. VOLLMAR B, GLASZ J, POST S... of inhibitors of the activ- ity of poly (ADP-ribose) synthetase on the ...

  

Source: University College London - Department of Medical Physics and Bioengineering, Biomedical Optics Research Laboratory

 

Collection: Engineering ; Biology and Medicine

 
29 JunD Protects the Liver from Ischemia/Reperfusion Injury by Dampening AP-1 Transcriptional Activation*
 

Summary:  JunD Protects the Liver from Ischemia/Reperfusion Injury by Dampening AP-1 Transcriptional... D is a major component of the AP-1 complex following liver ischemia/reperfusion (I/R) injury; how- ever, its... D in regulating AP-1 transcription following partial lobar I/R injury to the ...

  

Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa

 

Collection: Biology and Medicine

 
30 Expression of c-fos and c-jun During Hepatocellular Remodeling Following Ischemia/Reperfusion in Mouse Liver
 

Summary:  with the ing ischemia/reperfusion (I/R) are thought to involveextent of liver injury as determined by serum... liver injury.12-14 Despite the vast hours' postreperfusion and remained elevated out to 20 number... determi- were mounted in Citifluor antifadent, and sections were ana- nants of ...

  

Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa

 

Collection: Biology and Medicine

 
31 M. van de Bovenkamp G.M.M. Groothuis
 

Summary:  fibrosis due to viral, metabolic, or alcohol-induced liver injury is one of the leading causes of death... on stellate cell activation in human liver slices #12;58 Chapter 4 Abstract Introduction: Precision-cut liver... milieu. In the present study we evaluated human liver slices as a ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
32 Hepatic Parenchymal Replacement in Mice by Transplanted Allogeneic Hepatocytes Is Facilitated by Bone Marrow
 

Summary:  combined with PH or other forms of liver injury7 can provide the needed environment to achieve efficient re... radiation causes oxidative injury and double-stranded DNA breaks. Both result in an impairment of liver cell... - ations of severe infections or liver ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
33 579Clinical Science (2002) 102, 579586 (Printed in Great Britain) Effects of hepatic ischaemia/reperfusion
 

Summary:  /R injury. INTRODUCTION One of the major problems accompanying liver trans- plantation is determining... of ischaemia\reperfusion (I\R) injury after transplantation, including liver enzyme levels in the effluent... of subsequent liver injury and prognosis. The present ...

  

Source: University College London - Department of Medical Physics and Bioengineering, Biomedical Optics Research Laboratory

 

Collection: Engineering ; Biology and Medicine

 
34 College/University: 2000-2006 University of Rostock, Human Medicine
 

Summary:  . Inhibition of heme oxygenase-1 protects against tissue injury in carbon tetrachloride exposed livers. J Surg... , Hildebrandt A, Dold S, Menger MD, Vollmar B, Eipel C. Nitric oxide reduces organ injury and enhances... regeneration of reduced-size livers by elevation of hepatic arterial flow. BJS. 2007; ...

  

Source: Manstein, Dietmar J. - Department of Biophysical Chemistry, Medizinische Hochschule Hannover

 

Collection: Biology and Medicine

 
35 College/University: 2001-2004 : B.Sc. (Hons) Microbiology, University of Delhi,
 

Summary:  /Research: · To study the engraftment potential of multipotent adult progenitor cells in Fah knockout liver injury mouse... of patients suffering from liver injuries and failures. Hobbies and other interests: Traveling to different... in such a dynamic and challenging field as that of stem cell ...

  

Source: Manstein, Dietmar J. - Department of Biophysical Chemistry, Medizinische Hochschule Hannover

 

Collection: Biology and Medicine

 
36 M. van de Bovenkamp G.M.M. Groothuis
 

Summary:  Introduction Liver fibrosis due to viral or metabolic liver injury is one of the leading causes of death... liver slices as a new model to test the effects of anti-fibrotic drugs in vitro #12;74 Chapter 5... Abstract Background/Aims: Current cell culture models contributed significantly to the study of ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
37 HUMAN GENE THERAPY 16:299306 (March 2005) Mary Ann Liebert, Inc.
 

Summary:  detectable liver injury or toxicity. In all, the present study clearly demonstrated that hepatic arterial... -infusion or procedure related liver injury occurred, we measured serum ALT, a sensitive marker for liver injury, 2, 7... causing significant hepatocellular ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
38 Post-doctorant-INSERM U991-Universit de Rennes 1 : dbut 2012 (3 ans ou plus), sur l'Hpatotoxicit des mdicaments dans le cadre d'un projet europen. Contact Prof. Andr
 

Summary:  . Fiche Post-Doctoral Position in Drug-Induced Liver Injury A post-doctoral position will be available... best practice assays for predicting Drug-Induced Liver Injury in the human population. The major... objectives will be to develop new in vitro models and to analyze the mechanisms by which drug-induced ...

  

Source: Rennes, Université de - Faculté de Pharmacie

 

Collection: Biology and Medicine

 
39 General introduction General introduction
 

Summary:  and the deposition of extra cellular matrix (ECM) components. Chronic liver injury eventually leads to impaired... also contain the largest quantity of vitamin A in the body 8 . Upon liver injury, the HCS undergo... cell into myofibroblast-like cells. Following liver ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
40 J. Hemato. Ther. Hepatic oval (stem) cell expression of EDG receptors for
 

Summary:  in mouse chronic liver injury Yuri Y. Sautin, Marda Jorgensen, Bryon Petersen, Jean Sébastien. Saulnier... ,4-dihydrocollidine (DDC) in a mouse model of chronic liver injury, was associated with the expression of LPA1, LPA2... of oval cells during liver injury. As a ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics


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41 Liver tissue repair in a mouse model of toxicant-induced liver injury is associated with increased hepatic energy metabolism: A multinuclear magnetic resonance study
 

Summary:  Liver tissue repair in a mouse model of toxicant-induced liver injury is associated with increased... widely used in experimental animal settings to investigate the mechanisms of toxin-induced liver injury... is thought to cause hepatocyte death and consequently liver ...

  

Source: Max-Planck-Institut für biologische Kybernetik

 

Collection: Biology and Medicine

 
42 M. van de Bovenkamp G.M.M. Groothuis
 

Summary:  of an injurious stimulus. Precision-cut liver slices could provide such a system since in the liver slice all... Gils D.K.F. Meijer S.L. Friedman P. Olinga Precision-cut liver slices as a new model to study toxicity... as in fibrosis development in the liver. Current in vitro models for ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
43 Editorial Manager(tm) for Surgical and Radiologic Anatomy Manuscript Draft
 

Summary:  -D-09-00367 Title: Anthropometric characterization of the child's liver Article Type: Original Article... Keywords: liver; child; modeling; CT; growth Corresponding Author: Mr. Baptiste Sandoz, MSc Corresponding... of this retrospective study on twenty-five CT-scanners of children liver from 2 to 13 years old was to investigate

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
44 GENERAL INTRODUCTION Liver fibrosis
 

Summary:  by the excessive deposition of extracellular matrix (ECM) in response to chronic liver injury of various etiologies... the liver. In man, cholestasis mainly leads to liver injury in acinar zone 1 and is characterized... hepatitis-induced liver ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
45 Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after
 

Summary:  45 Chapter 2 Phase I and phase II metabolic activities are retained in liver slices from mouse, rat... , the Netherlands Adapted from Toxicology in Vitro 18 (2004): 121-128 #12;Liver slices cryopreservation 46 Abstract... Precision-cut liver slices are described as valuable tool for in vitro metabolism studies of potential drug

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
46 Fig 1. In vivo SPECT images and ex vivo autoradiograph left ventricular (LV) Tc-DPA-amine-(CO)3 in a rat with myocardial ischemia-reperfusion
 

Summary:  -DPA-amine-(CO)3 in a rat with myocardial ischemia-reperfusion injury (left panel). Increased liver uptake of 99m... Tc-DPA-amine-(CO)3 was found in the mouse liver with anti-fas-induced apoptosis (middle and right... panel) compared to a control mouse. The liver apoptosis was determined by caspase-3 ...

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine

 
47 Introduction 1 Liver fibrosis
 

Summary:  is the progressive accumulation of connective tissue in the liver, which can be caused by chronic liver injury... on the type of liver injury and the time after injury. In addition, besides activation of hepatic stellate... cells and/or other fibrogenic cells, ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
48 Dynamics of Short-Term Gene Expression Profiling in Liver Following Thermal Injury
 

Summary:  Dynamics of Short-Term Gene Expression Profiling in Liver Following Thermal Injury Qian Yang, M... ; in- flammation; liver. INTRODUCTION Thermal injury, one of the most severe forms of trauma, triggers... and transcriptional profiling have been used to elucidate genome-wide changes in the ...

  

Source: Rutgers University, Rutgers Center for Operations Research

 

Collection: Engineering

 
49 Hepatocyte Growth Factor Induces Hepatocyte Proliferation In Vivo and Allows for Efficient Retroviral-Mediated
 

Summary:  with retroviral vectors in vivo without the prior induction of liver injury. The level of hepatic gene transfer... of HGF rise over 20-fold rapidly after partial hepatectomy and acute toxic liver injury and remain... during the first 36 hours postoperatively. Thus, liver ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
50 Diabetes Metab . Author manuscript Cannabinoid receptors as novel therapeutic targets for the management of
 

Summary:  -mortality. The cannabinoid system is increasingly emerging as a crucial mediator of acute and chronic liver injury. Recent... and the obesity epidemic ( ) and currently accounts for a rising cause of liver injury, with a 20 30 prevalence... and the liver are also incriminated in the ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
51 Morphogenesis of chicken liver: identification of localized growth zones and the role of h-catenin/Wnt in size regulation
 

Summary:  Morphogenesis of chicken liver: identification of localized growth zones and the role of h... to the liver parenchyma. Regulation of this process contributes to the final size and shape of the particular... organs, including the liver. We identified the distribution of liver growth zones using an embryonic

  

Source: Chuong, Cheng-Ming - Laboratory of Tissue Development and Engineering & Department of Pathology, University of Southern California

 

Collection: Biology and Medicine

 
52 HUMAN GENE THERAPY 13:653663 (March 20, 2002) Mary Ann Liebert, Inc.
 

Summary:  liver cell plates). Alanine aminotransferase assay As a marker for hepatic injury, serum alanine... livers showed relatively normal histol- ogy with no observable liver injury. Biodistribution... of liver injury. Because administration of TCPOBOP ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
53 Species and strain differences in drug metabolism in liver and intestine
 

Summary:  1 Species and strain differences in drug metabolism in liver and intestine Marcella Martignoni #12... ;2 RIJKSUNIVERSITEIT GRONINGEN Species and strain differences in drug metabolism in liver and intestine Proefschrift... - mediated metabolism Chapter 2 Phase I and phase II metabolic activities 49 are retained in liver slices

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
54 Local carboplatin delivery and tissue distribution in livers after radiofrequency ablation
 

Summary:  Local carboplatin delivery and tissue distribution in livers after radiofrequency ablation A... of the liver. We hypothesized that the tissue architecture damaged by the ablation process facilitates the drug... penetration in the liver and potentially enlarges the therapeutic margin in the local treatment of cancer

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine

 
55 Chapter5Accumulation in hepatic stellate cells and antifibrotic effect of losartan-M6PHSA in the CCL4
 

Summary:  caused by chronic liver injury due to various inciting stimuli including viral hepatitis (especially... ). During chronic liver injury, however, activated HSC express functional angiotensin receptors and generate... in the first stages (hours) during acute liver ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
56 Changes in Tissue Oxygenation of the Porcine Liver Measured by Near-Infrared
 

Summary:  damage caused by ischemia and reperfusion injury is a well-recognized complication of liver trauma,1... of the severity of warm ischemia-reperfusion injury8 and is of prognostic value for survival in liver transplan... to achieve intrahe- patic hemostasis in 75 patients with severe ...

  

Source: University College London - Department of Medical Physics and Bioengineering, Biomedical Optics Research Laboratory

 

Collection: Engineering ; Biology and Medicine

 
57 1854 IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, NO 10, VOL. 51, OCTOBER 2004 Communications______________________________________________________________________
 

Summary:  ______________________________________________________________________ Modeling of Elastic Modulus Evolution of Cirrhotic Human Liver H. M. Yin, L. Z. Sun*, G. Wang, and M. W... modulus evolution of cirrhotic human liver cor- related with different pathological stages... . Microstructurally, the cirrhotic liver is hypothesized to ...

  

Source: Virginia Tech - Wake Forest University School of Biomedical Engineering and Sciences, Biomedical Imaging Division

 

Collection: Engineering ; Biology and Medicine

 
58 ABDOMINAL CT CHEST CT CT EXAMINATION
 

Summary:  Abdominal mass / swelling Ascites Injury to abdomen Injury to pelvis Paralytic ileus Intestinal... obstruction Peptic ulcer Pancreatitis Liver disease Cholecystitis Diverticulitis Peritonitis... Complications of transplanted organ, liver Postoperative infection Hemorrhage / seroma complicating ...

  

Source: Jacob, Mathews - Departments of Biomedical Engineering & Electrical and Computer Engineering, University of Rochester

 

Collection: Biology and Medicine ; Engineering

 
59 Chapter7Summarizing discussion, conclusions and future perspectives
 

Summary:  model of liver fibrosis, the injury is induced by administration of CCl4 and phenobarbital... ,P., and Abboud,H.E. 1994. Expression of Platelet-Derived Growth Factor in a Model of Acute Liver Injury. Hepatol... segments in cholestatic liver injury. Lab Invest ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
60 Journal of Controlled Release 83 (2002) 415425 www.elsevier.com/locate/jconrel
 

Summary:  kinetics in livers before and following radiofrequency thermal ablation. Iohexol, a CT contrast agent... , was used as a drug-mimicking molecule. Release of iohexol in healthy and ablated rabbit livers over 48 h... . The results show that iohexol release in ablated livers is significantly slower than both release in normal

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine


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61 Distamycin A Inhibits HMGA1-Binding to the P-Selectin Promoter and Attenuates Lung and Liver Inflammation
 

Summary:  to electrophoresis. In separate experiments to test for presence of specific proteins within the TNF-a-inducible... ) was incubated with the radiolabeled probe prior to gel electrophoresis. Dist A decreased binding within the TNF-a-inducible... ) [38] would decrease TNF-a-induced P-selectin promoter activity (Fig. 6B). BAEC cells ...

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
62 General discussion and perspectives Marcella Martignoni1, Ruben de Kanter2 and Geny Groothuis3
 

Summary:  human/rodent specific CYP3A inducers during the early phase of drug development [13]. However... will be discussed. § 2. The effect of the cryopreservation of liver slices of different species, including man... : comparison of metabolic activities Precision-cut liver slices are a valuable tool for in vitro ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
63 Analysis of liver development, regeneration, and carcinogenesis by genetic marking studies
 

Summary:  cell proliferation of small hepatocytes in liver injury induced by D-galactosamine. Am.). Pathol. 139... Analysis of liver development, regeneration, and carcinogenesis by genetic marking studies... , Washington University School of Medicine, St. Louis, Missouri 63110, USA Analysis of liver regeneration

  

Source: Ponder, Katherine P. - Departments of Medicine & Biochemistry and Molecular Biophysics, Washington University in St. Louis

 

Collection: Biology and Medicine

 
64 Chapter2General Introduction: Potential strategies to treat liver fibrosis
 

Summary:  to the production of inflammatory mediators and ultimately to liver injury. Moreover, during liver injury... of extracellular matrix (ECM) components in the process of wound healing (2;11). During chronic liver injury... which is dysbalanced during chronic ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
65 ForPeerReview Hepatologyinserm-00519450,version1-20Sep2010 Author manuscript, published in "Hepatology (Baltimore, Md.) 2010;52(3):1046-59"
 

Summary:  #12;ForPeerReview 1 BENEFICIAL PARACRINE EFFECTS OF CANNABINOID CB2 RECEPTORS ON LIVER INJURY... the impact of CB2 receptors on the regenerative process associated with liver injury. Following acute... and remained undetectable in hepatocytes. Administration of CCl4 to CB2-/- mice accelerated ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
66 University of the Joseph Fourier-Grenoble UFR of Biology
 

Summary:  . Hepatitis implies injury to the liver characterized by the presence of inflammatory cells in the liver... by chronic liver injury and regeneration in a context of inflammation, immune response and oxidative DNA... , induced by chronic liver ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
67 10.1101/gad.2029411Access the most recent version at doi: 2011 25: 1193-1203Genes Dev.
 

Summary:  injury livers, respectively. Gene expression analyses revealed that Sox9 was expressed exclusively... of novel cell surface markers developed for cells emerging during this type of liver injury has permitted... , activated in response to liver injury, marks progenitor ...

  

Source: Sander, Maike - Departments of Pediatrics and Cellular and Molecular Medicine, University of California at San Diego

 

Collection: Biology and Medicine

 
68 INTRODUCTION During hypoxic-ischemic incidents, oxygen supply to
 

Summary:  and 8-OHG expression are increased in the liver following ischemia-reperfusion injury.25 A novel finding... is maintained in the brain, but not the liver, following mild hypoxia Glenda M. Bishop1 *, Mark A. Smith1... to re-oxygenate prior to examination. Brain, liver and skeletal muscle were examined for ...

  

Source: Wisconsin at Madison, University of - Laboratory of Endocrinology, Aging and Disease

 

Collection: Biology and Medicine

 
69 Filename: c:\sarosdm\copydir\523-h.f3f, Date: 10-7-103 8:36:10 Sheet: 1, Copy: Front, Scale: 100%, Type: Manufacturing
 

Summary:  Abnormal bowel sounds Diarrhea Jaundice Abdominal mass / swelling Ascites Injury to abdomen Injury... to pelvis Paralytic ileus Intestinal obstruction Peptic ulcer Pancreatitis Liver disease Cholecystitis... Diverticulitis Peritonitis Complications of transplanted organ, liver Postoperative infection ...

  

Source: Jacob, Mathews - Departments of Biomedical Engineering & Electrical and Computer Engineering, University of Rochester

 

Collection: Biology and Medicine ; Engineering

 
70 APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development
 

Summary:  APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development... 2008 Keywords: wnt Endoderm Liver Regeneration APC Zebrafish -catenin Developmental signaling pathways... hepatoblastoma, an embryonal form of liver cancer, suggesting that Wnt affects hepatic progenitor cells

  

Source: Harvard University, North and Goessling Labs

 

Collection: Biology and Medicine

 
71 Experimental study of liver dysfunction evaluated by direct indocyanine green clearance using near infrared spectroscopy
 

Summary:  Experimental study of liver dysfunction evaluated by direct indocyanine green clearance using near... Department of Surgery and Liver Transplant Unit, Royal Free and University College Medical School... : Professor B. R. Davidson, University Department of Surgery and Liver Transplant Unit, Royal Free

  

Source: University College London - Department of Medical Physics and Bioengineering, Biomedical Optics Research Laboratory

 

Collection: Engineering ; Biology and Medicine

 
72 Acta Physiol (Oxf) . Author manuscript AMP-activated protein kinase in the regulation of hepatic energy
 

Summary:  ( ) , possibly by a protein kinase A-induced phosphorylation and activation of LKB1 (Sim and Hardie, 1988... in the fibrotic response during the progression of NASH ( , ). Stimuli such as liver injury activate... should be adressed to: Benoit Viollet Abstract Because the ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
73 Introduction Asthemajorsiteofxenobioticmetabolism,theliverplaysacentral
 

Summary:  intermediates mediate toxic responses, the liver is potentially susceptible to injury1 during the act... ,inhalation,dermalabsorption,or injection), the liver often shows the earliest signs of injury due... to better understand the causes of drug-induced liver ...

  

Source: Androulakis, Ioannis (Yannis) - Biomedical Engineering Department & Department of Chemical and Biochemical Engineering, Rutgers University

 

Collection: Engineering ; Biology and Medicine

 
74 Introduction Asthemajorsiteofxenobioticmetabolism,theliverplaysacentral
 

Summary:  intermediates mediate toxic responses, the liver is potentially susceptible to injury1 during the act... of drug-induced liver injury;similar efforts are underway at the Environmental Protection Agency (EPA... on the prediction of clinical outcomes of liver injury ...

  

Source: Rutgers University, Rutgers Center for Operations Research

 

Collection: Engineering

 
75 Blockade of self-reactive IgM significantly reduces injury in a murine model of acute
 

Summary:  ;28:1067­1080. 34. el-Lati SG, Dahinden CA, Church MK. Complement peptides C3a- and C5a-induced mediator release... of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction Michael... resulting in ischaemia/reperfusion (I/R) injury is a major cause of mortality in the western world

  

Source: Carroll, Michael C. - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
76 In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers
 

Summary:  In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable... treatment of liver cancers. In this study, the in vivo transport properties of doxorubicin in thermo... - ablated and nonablated rabbit livers were characterized and compared. Doxorubicin was released from

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine

 
77 Summary, general discussion and future perspectives
 

Summary:  , which is a response to chronic liver injury. This cell starts to proliferate and accumulate within... of liver fibrosis was found after terminating the injury 4 . The resolution was accompanied by the loss... is that the hepatic injury that leads to liver fibrosis, ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
78 B. anthracis Trapping in Liver JID 2009:200 (1 November) 1381 M A J O R A R T I C L E
 

Summary:  B. anthracis Trapping in Liver · JID 2009:200 (1 November) · 1381 M A J O R A R T I C L E... Encapsulated Bacillus anthracis Interacts Closely with Liver Endothelium Alejandro Piris-Gimenez,1,2,a Jean... % of the bacteria being trapped in the liver. Competition experiments with purified capsule polyglutamate inhibited

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
79 Metabolic Response of Perfused Livers to Various Oxygenation Conditions
 

Summary:  that the rat liver oxygen demand could be up to 400 mmol/h/g liver after experimental burn injury. Since more... fluxes in hypermetabolic livers induced through burn injury and cecal ligation and puncture in rats... the liver metabolic response to experimental burn ...

  

Source: Ierapetritou, Marianthi G.- Department of Chemical and Biochemical Engineering, Rutgers University

 

Collection: Engineering

 
80 IL-6 Deficiency Attenuates Murine Diet-Induced Non-Alcoholic Steatohepatitis
 

Summary:  , liver cell injury and varying degrees of fibrosis. NASH belongs to the spectrum of non- alcoholic fatty... resulted in a 5.5-fold increased level of ALT. This biochemical liver injury induced by MCD diet... , as revealed both histologically and by analysing gene expression, liver ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics


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81 SUMMARY, GENERAL DISCUSSION AND CONCLUSIONS
 

Summary:  is the response to a variety of chronic injurious events to the liver, induced by chronic viral hepatitis, iron... of macrophages and perisinusoidal cells to cholestatic liver injury. Am J Pathol 1993; 142: 511-8. 8. de Borst MH... 8 SUMMARY, GENERAL DISCUSSION AND CONCLUSIONS #12;Chapter 8 144 SUMMARY ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
82 Biol Trace Elem Res . Author manuscript Burn-induced oxidative stress is altered by a low zinc status: kinetic study
 

Summary:  GPX activity after burn injury. In this study, Zn deficiency leads to a lower liver GPx activity (D5... Figure 5 Evolution of RBC, liver and kidney glutathione peroxidase levels after burn injury in control (C... after injury. Kinetic evolutions of zinc status, plasma oxidative stress ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
83 Expansion of Donor Hepatocytes After Recombinant Adenovirus-Induced Liver Regeneration in Mice
 

Summary:  PA results in asynchronous liver injury beginning within various animal models. Functionally active... of producing irreversible liver injury with 19. Lieber A, Vrancken Peeters MTFD, Gown A, Perkins J, Kay MA... induces liver regenera- titer the amount of liver ...

  

Source: Kay, Mark A. - Department of Genetics, Stanford University

 

Collection: Biology and Medicine

 
84 Activin A-Induced HepG2 Liver Cell Apoptosis: Involvement of Activin Receptors and Smad Proteins*
 

Summary:  Activin A-Induced HepG2 Liver Cell Apoptosis: Involvement of Activin Receptors and Smad Proteins... A-induced cell death process in liver cells. (Endocrinology 141: 1263­ 1272, 2000) APOPTOSIS... the roles of activin receptors and downstream signaling proteins in activin A-induced ...

  

Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
85 Changes in specific metabolic pathways are essential steps in the early apoptotic process in the liver S. Gottschalk1,2
 

Summary:  mode of cell death in most liver injuries.1 Mitochondria are not only the key regulatory centers... with liver injury (>50- fold elevation in serum ALT and caspase-3 activities), and histological evidence... of massive apoptosis, 2) very early (< 1.5 h), when no liver ...

  

Source: Max-Planck-Institut für biologische Kybernetik

 

Collection: Biology and Medicine

 
86 Pathway analysis of liver metabolism under stressed condition Mehmet A. Orman a
 

Summary:  November 2010 Available online 14 December 2010 Keywords: Pathway analysis Liver metabolism Burn injury a b... the perfused livers of fasted rats receiving burn injury. Utilizing unique decomposition techniques... in the hepatic metabolic network to gain a better understanding of the effects of burn ...

  

Source: Rutgers University, Rutgers Center for Operations Research

 

Collection: Engineering

 
87 STEATOHEPATITIS/METABOLIC LIVER DISEASE Genetic Variation in the PNPLA3 Gene Is Associated with
 

Summary:  with Alcoholic Liver Injury in Caucasians Felix Stickel,1 * Stephan Buch,2 * Katharina Lau,3 Henriette Meyer zu... ,043 alcoholic patients with or without alcoholic liver injury and in 376 at-risk drinkers from a population... comprises various degrees of liver injury ...

  

Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health,

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
88 Rullier A et al. PAR-1 knock-out protects against liver fibrosis1 Protease-activated receptor 1 (PAR-1) knock-out reduces experimentally-induced liver
 

Summary:  in hepatic stellate cells, and is induced by in vivo liver injury in the rat. Hepatology 30: 951-958, 1999... . Expression of the thrombin receptor in human liver: up-regulation during acute and chronic injury. Hepatology... /fibrin during short-term and long-term rat liver ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
89 Liver Deformation in Ahr-Null Mice: Evidence for Aberrant Hepatic Perfusion In Early Development
 

Summary:  Liver Deformation in Ahr-Null Mice: Evidence for Aberrant Hepatic Perfusion In Early Development... venosus and smaller livers throughout life. We tested the hypothesis that these hepatic aberrations... of Ahr / fetal livers as early as embryonic day 15.5, with an increasing incidence up to postnatal day 1

  

Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
90 AMPK in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.
 

Summary:  by a protein kinase A- induced phosphorylation and activation of LKB1 (Kimball et al., 2004). In addition... (Bataller and Brenner, 2005, Friedman, 2004). Stimuli such as liver injury activate and transdifferentiate... : AMPK in the liver Key words: AMPK, energy metabolism, ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
91 Alice A. Chen: Notable Inventions Winner of the 2011 $30,000 Lemelson-MIT Student Prize
 

Summary:  liver injuries, which enable human cell repopulation of the mouse liver but are costly, time... . Humanized Mice with Tissue-Engineered Livers Drug development is risky, expensive and time consuming... are safe for human clinical trials. However, because of stark differences between animal and human ...

  

Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biotechnology ; Biology and Medicine

 
92 UNIVERSITY OF FLORIDA PREPLACEMENT EXAM: MEDICAL HISTORY NAME _________________________________________ SSN ___________________________
 

Summary:  Disease__________________________ O O Ulcers________________________________ O O Liver Disease... ______________________________ O O Neck Injury___________________________ O O Shoulder Injury________________________ O O Wrist... Problem ________________________ O O Finger Injury__________________________ O O ...

  

Source: Jawitz, James W. - Soil and Water Science Department, University of Florida

 

Collection: Environmental Sciences and Ecology

 
93 Mehmet Ali Orman ALL RIGHTS RESERVED
 

Summary:  profiles of liver- in rat models receiving 20% total body surface area (TBSA) scald burn injury or cecal... DYNAMICS OF SHORT TERM GENE EXPRESSION PROFILING IN LIVER FOLLOWING THERMAL INJURY AND SEPSIS... ...

  

Source: Rutgers University, Rutgers Center for Operations Research

 

Collection: Engineering

 
94 A GUIDE TO GIVING: SAMPLE AREAS OF SUPPORT Annual Fund for Excellence (unrestricted)
 

Summary:  gastrointestinal diseases such as acid reflux, swallowing disorders, liver transplants, cancer surveillance... , and treatment of the esophagus, stomach, colon, and liver. Eye Institute For over 30 years, the Eye Institute... vision problems. Injury Research Center The mission of the Injury Research Center at ...

  

Source: Medical College of Wisconsin, Biotechnology and Bioengineering Center, Computational Bioengineering Group

 

Collection: Biology and Medicine

 
95 Arming drug carriers to disable the Hepatic Stellate Cell: The targeted delivery of apoptosis-inducing drugs to the fibrotic liver
 

Summary:  toxic injuries, viral hepatitis, hepatocellular carcinoma, metabolic liver disorders, biliary... . Chronic liver injury eventually leads to impaired regeneration and hepatocytes are increasingly replaced... the largest quantity of vitamin A in the body 8 . Upon liver ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
96 TISSUE ENGINEERING Volume 8, Number 5, 2002
 

Summary:  TISSUE ENGINEERING Volume 8, Number 5, 2002 © Mary Ann Liebert, Inc. Review Engineering Liver... of liver disease has been greatly improved by the advent and evolution of liver trans- plantation. However... , as demand for donor organs continues to increase beyond their availability, the need for alternative ...

  

Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biotechnology ; Biology and Medicine

 
97 VALIDATION AND COMPARISON OF SIMPLE NON INVASIVE INDEXES FOR PREDICTING LIVER FIBROSIS IN HIV-HCV COINFECTED PATIENTS: ANRS CO3
 

Summary:  M. Liver injury during highly active antiretroviral therapy: the effect of hepatitis C coinfection... VALIDATION AND COMPARISON OF SIMPLE NON INVASIVE INDEXES FOR PREDICTING LIVER FIBROSIS IN HIV... -HCV coinfected patients from the ANRS-CO3 Aquitaine cohort who underwent liver biopsy were studied. Fibrosis

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
98 Species differences between mouse, rat, dog, monkey and human cytochrome P450-mediated drug metabolism
 

Summary:  and physiological properties with body weight, such as, for example, liver weight as a percentage of body weight... can be found in virtually all organs notably the liver, intestine, skin, nasal epithelia, lung... and kidney, but also in testis, brain etc. However, the liver (300 pmol of total CYPs/mg microsomal protein

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
99 Molecular Biology of the Cell Vol. 14, 23272341, June 2003
 

Summary:  3 - untranslated region (UTR) mRNA binding proteins in stellate cells after liver injury... Da ECE-1 3 UTR mRNA binding proteins. These data indicate that liver injury and the hepatic wound healing... but also molecular mechanisms by which TGF- controls ET-1 production. MATERIALS AND METHODS ...

  

Source: Rockey, Don - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
100 Basic Studies Analysis of the functional integrity of
 

Summary:  , retained hepatic function and proliferated in response to liver injury. Transplanted hepatocytes were... Basic Studies Analysis of the functional integrity of cryopreserved human liver cells including... , Robert Susick2 and Sanjeev Gupta1 1 Departments of Medicine and Pathology, Marion Bessin Liver Research

  

Source: Giri, Ranjit K. - National Brain Research Centre (India)

 

Collection: Biology and Medicine


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