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Sample search results for: a2 mediated tumor

Page:   2  3  4  5 
 
1 Three-Dimensional Diffuse-Interface Simulation of Multispecies Tumor GrowthII
 

Summary:  as the mass fraction of viable cells, say V. For this case the source terms have the form S1 = 1 T (A2 + NH... (nN - n)2 - L1) Q(T), (15) S2 = 1 T (n2 - A2 - NH(nN - n)2) Q(T). (16) The dead cell population includes... Three-Dimensional Diffuse-Interface Simulation of Multispecies Tumor ...

  

Source: Cristini, Vittorio - Departments of Biomedical Engineering & Mathematics, University of California, Irvine

 

Collection: Mathematics ; Engineering

 
2 ANTITUMOR IMMUNITY AND THE ROLE OF IMMUNUNE-MEDIATED ACTIVATION OF CYTOTOXIC T LYMPHOCYTES: A MATHEMATICAL MODEL
 

Summary:  Inactivation rate of macrophages, NK and helper T cells 1! Immune-mediated CTL activation rate 2! Tumor-mediated... .2! = , 2 0.3! = , 0.05! = , 1 0.02µ = , 1 0.07! = , 2 0.07! = , 2 0.1a = , 2 2b = , 2 ^ 0.01µ = , 3! = , 0... ! ) is an order of magnitude or more, larger than the rate which Figure 7. ...

  

Source: Kuang, Yang - Department of Mathematics and Statistics, Arizona State University

 

Collection: Mathematics

 
3 Modulation of in Vivo Tumor Radiation Response via Gold Nanoshell-Mediated
 

Summary:  dimensions in two orthogonal directions (long axis: a1; short axis: a2) twice weekly. Tumor volume... was calculated using the expression (/6)·(a1)·(a2)2 and plotted over time as represented in Figure 2a. The tumor... Modulation of in Vivo Tumor ...

  

Source: Tunnell, James W. - Department of Biomedical Engineering, University of Texas at Austin

 

Collection: Biology and Medicine ; Engineering

 
4 Journal of Theoretical Biology 245 (2007) 677704 Nonlinear simulation of the effect of microenvironment on
 

Summary:  of microenvironment on tumor growth Paul Macklin, John Lowengrubà Department of Mathematics, University of California... and investigate a model for solid tumor growth that incorporates features of the tumor microenvironment. Using... characteristics of the tumor and the tumor ...

  

Source: Lowengrub, John - Department of Mathematics, University of California, Irvine

 

Collection: Mathematics

 
5 The combined actions of NK and T lymphocytes are necessary to reject an EGFP1 mesenchymal tumor through mechanisms dependent on NKG2D and IFNc
 

Summary:  infiltrate that mediates tumor rejection along with some DC. The effects of IFNc, produced at the tumor site... eradication. NK recognition of tumor cells was mediated by the NKG2D-activating receptor and blocking its... cells in tumor control.2­5 In addition, ...

  

Source: Raulet, David - Department of Molecular and Cell Biology, University of California at Berkeley

 

Collection: Biology and Medicine

 
6 Cytotherapy. Author manuscript Whole lymphoma B cells allow efficient cross-presentation of antigens by
 

Summary:  , whereas lymphoma B cells were HLA-A2-, making tumor cells unable to directly present viral+ + antigens... iodide staining.% Peripheral blood was obtained from HLA-A2 healthy volunteers who gave informed consent... were 100 CD14 and CD64 .% + % + + In order to generate anti-viral CD8 ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
7 2011;71:976-987. Published OnlineFirst December 8, 2010.Cancer Res Dana M. Brantley-Sieders, Charlene M. Dunaway, Meghana Rao, et al.
 

Summary:  average Æ SD. EphA2 represses Slit2 to mediate angiocrine tumor growth and invasion www... angiocrine-mediated tumor growth and motility in the context of EphA2 Onthebasisofexpressiondata... SD. ...

  

Source: Wu, Jane Y. - Center for Genetic Medicine & Department of Neurology, Northwestern University

 

Collection: Biology and Medicine

 
8 A mathematical model to study the eects of drug resistance and vasculature on the response of solid tumors to
 

Summary:  # # ### # # e ## 1 # # # e ## 2 # and # # ### # # e ## 2 # # # e ## 1 # # # #A#2# The values for ## #, # 1... of solid tumors to chemotherapy Trachette L. Jackson a, * , Helen M. Byrne b a Department of Mathematics... that describes the reduction in volume of a vascular tumor in re- sponse to speci®c ...

  

Source: Jackson, Trachette L. - Department of Mathematics, University of Michigan

 

Collection: Biology and Medicine ; Mathematics

 
9 Identification of alterations in DNA copy number in host stromal cells during tumor progression
 

Summary:  with survival and invasive capacity of colorectal and ovarian cancers (19­21). Additionally, EphA2 and EphB2... (Kv4.2) Gain 2.40 6qA2 69.48 BOT0028 Breast MDA-MB-435s Mup1; Mup2 Major urinary protein 1; Major... angiogenesis has also been convincingly demonstrated by the tumor-derived ...

  

Source: Botstein, David - Lewis-Sigler Institute for Integrative Genomics & Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine

 
10 [CANCER RESEARCH 62, 62786288, November 1, 2002] Single Cell Behavior in Metastatic Primary Mammary Tumors Correlated with
 

Summary:  with this is the overexpression of several collagen genes involved in ECM assembly (Col3a1, Col5a2, and Col6a3) in MTC tumors... .15 Col5a2 AA034564 Collagen, type V, 2 0.05 0.19 Col6a3 W16221 Collagen, type VI, 3 0.22 0.11 Lamc2 W... , whereas this is not seen in MTC ...

  

Source: Condeelis, John S - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University; Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
11 Journal of Theoretical Biology 243 (2006) 517531 Modeling the effects of vasculature evolution on early
 

Summary:  at the same angle (Fig. 1a). 2. The vessel cannot cause the intersection of three vessels at one lattice site... , ð1Þ qa1 qt ¼ ba1eiðpi þ hi þ niÞðe0 À a2 1=Ka... À a2 2=KaÞ ...

  

Source: Torquato, Salvatore - Department of Chemical Engineering, Princeton University

 

Collection: Materials Science ; Chemistry

 
12 Modeling doxorubicin transport to improve intratumoral drug delivery to RF ablated tumors
 

Summary:  transport model, AC At ¼ D A2 C Ax2 þ A2 C Ay2 þ A2 C Az2 À gC ð6Þ Boundary and initial conditions were... in livers after radiofrequency ablation, J. Biomed. Mater. Res. 67A (2) (2003) 510­516. [13] B.D. Weinberg... ...

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine

 
13 CANCER CELL : JANUARY 2004 VOL. 5 COPYRIGHT 2004 CELL PRESS 1 Ever since the discovery of caspases as
 

Summary:  in mammals, including Smac/DIABLO, HtrA2/Omi, and XAF1 (Liston et al., 2003). Because both Smac and HtrA2... caspases may be exploited to kill tumor cells. However, caspases are tightly regulated in many different... that are different between normal and tumor cells ...

  

Source: Wu, Hao - Department of Biochemistry, Cornell University

 

Collection: Biology and Medicine

 
14 A head holder for magnetic resonance imaging that allows the stereotaxic alignment of spontaneously occurring intracranial
 

Summary:  occurring intracranial mouse tumors Tsuyoshi Tada a,1 , Mike Wendland b , Nathan Watson a,2 , Nagato... holder (Fig. 1, panel A). 2.3. Stereotaxic injections A miniaturized stereotaxic instrument (Stoelting Co... ,d, * a Department of Neurological Surgery, Preuss Laboratory of Molecular ...

  

Source: Israel, Mark A.- Department of Genetics, Dartmouth College

 

Collection: Biology and Medicine

 
15 Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates
 

Summary:  A2, Cox1, Cox2, LpI, PPAR, and PPAR, affect the multiplicity of intestinal tumors in Min mice (4... stimulate Min tumorigenesis by mediating angiogenesis when tumors exceed a critical size of 1mm (5). However... . Pharmacogenetics and regulation of human cytochrome P450 1B1: implications ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
16 Nonlinear Modeling and Simulation of Tumor Vittorio Cristini1,
 

Summary:  , the flux J = 0 and (11) indicates that there exists a critical Gl = R-3 2l(l2 -1) 2-A[2+RIl+1(R... Nonlinear Modeling and Simulation of Tumor Growth Vittorio Cristini1, , Hermann B. Frieboes1... , Austin Introduction The effects of the interaction between cellular- and tumor-scale processes on cancer

  

Source: Lowengrub, John - Department of Mathematics, University of California, Irvine

 

Collection: Mathematics

 
17 Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse
 

Summary:  -MICA-Opsonized Melanoma, Ovarian, or Breast Cancer Cells. HLA-A2 and MICA tumor lines with previously known or newly... healthy HLA-A2 donors were cocultured with low-dose irradiated red fluorescent dye-labeled tumor cells... was scrutinized by using DCs and CD8 T ...

  

Source: Spies, Thomas - Basic Sciences Division, Fred Hutchinson Cancer Research Center

 

Collection: Biology and Medicine

 
18 IOP PUBLISHING PHYSICAL BIOLOGY Phys. Biol. 8 (2011) 015017 (22pp) doi:10.1088/1478-3975/8/1/015017
 

Summary:  Published 7 February 2011 Online at stacks.iop.org/PhysBio/8/015017 Abstract The holy grail of tumor... in tumor growth. Here we review the research work that we have done toward the development of an `Ising... . This is followed by a discussion of the extension of the model to study the effect on the tumor dynamics

  

Source: Torquato, Salvatore - Department of Chemical Engineering, Princeton University

 

Collection: Materials Science ; Chemistry

 
19 Anti-Cancer Drugs 1996, 7, pp. 785-791 Electrochemotherapy with bleomycin in SA-1
 

Summary:  electrochemotherapy treat- Granulocytes Monocytes ~r~~~iI.ill '~~iII1II (/) C')= C\Ja> ~<..l CI:a> _.2: 0:", ~~Q... Anti-Cancer Drugs 1996, 7, pp. 785-791 Electrochemotherapy with bleomycin in SA-1 tumor... Miklavcic2 and Antonija Kotnik3 Department of Tumor Biology, Institute of Oncology, Zaloska 2, ...

  

Source: Ljubljana, University of - Faculty of Electrical Engineering, Laboratory of Biocybernetics

 

Collection: Engineering ; Biology and Medicine

 
20 RESEARCH ARTICLE Nonlinear Optical Imaging to Evaluate the Impact of
 

Summary:  . Tumor cells of mammary tumor tissues imaged with coherent anti-Stokes Raman scattering (CARS) at (A) 2... and Tumor Stroma Thuc T. Le, Charles W. Rehrer, Terry B. Huff, Maxine B. Nichols, Ignacio G. Camarillo... to evaluate the impact of obesity on the composition of mammary gland and ...

  

Source: Cheng, Ji-Xin - School of Biomedical Engineering & Department of Chemistry, Purdue University

 

Collection: Materials Science ; Biology and Medicine


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21 Neurosurgery 1992-98 April 1998, Volume 42, Number 4
 

Summary:  , to promote anti-tumor cell-mediated immunity. Interleukin-12 (IL-12) is a suitable cytokine for these tasks... T cells toward the T helper type 1 (Th-1) phenotype (8) , which is crucial for anti-tumor cell-mediated... think that the 9L tumor regression and prevention observed in our ...

  

Source: Low, Walter C. - Department of Integrative Biology and Physiology, University of Minnesota

 

Collection: Biology and Medicine

 
22 Gene expression profiling identifies clinically relevant subtypes of prostate cancer
 

Summary:  A2, SPARC, ABCA5 and BGN were reported by Singh et al. (17) to correlate with tumor grade; however... expression features (Fig. 1 g­i) included genes related to extracellular matrix (e.g., COL1A1, COL1A2, CSPG2... this clinical heterogeneity, we profiled gene expression in 62 primary ...

  

Source: Botstein, David - Lewis-Sigler Institute for Integrative Genomics & Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine

 
23 DISCRETE AND CONTINUOUS Website: http://AIMsciences.org DYNAMICAL SYSTEMSSERIES B
 

Summary:  + f ~y2 . (58) Therefore ( × A) · n at x is approximated by: [ × A] · n a2 - b1, (59) where a2 and b1... -284. [31] R.A. Gatenby, E.T. Gawlinski, A.F. Gmitro, B. Kaylor, and R.J. Gillies, Acid-Mediated Tumor... 3, May 2007 pp. 581­604 NONLINEAR THREE-DIMENSIONAL ...

  

Source: Nie, Qing - Department of Mathematics, University of California, Irvine

 

Collection: Mathematics

 
24 Mathematical Model of Pulsed Immunotherapy for Superficial Bladder Cancer
 

Summary:  of Cell-Mediated Immune Response to Tumor Growth. Cancer Research, 65 (17), 7950-7958. 11. De Pillis, L... operational meaning. For these reasons we choose the scaling cells (A2)6 ui00 10TTEB 00 ==== (similar... tumor destruction occurs but undesirable side effects are maintained at low ...

  

Source: Stone, Lewi - Department of Zoology, Tel Aviv University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
25 UNIVERSIT PARIS-SUD 11 Facultde Mdecine Paris Sud
 

Summary:  opposing STAT1- and NF-B-mediated anti-tumor Th1 tel-00636891,version1-28Oct2011 #12;16 response (IL-12... cells are deposited in the tumor stromal and locally activate FcR-mediated signaling on resident... The crosstalk between dying tumor cells and immune effectors within ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
26 Genome Biology 2007, 8:R131 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation
 

Summary:  (Mif, Pik1), cell cycle progression and checkpoint control (Id2, Ptp4A2, Tp53). From the 1... relatively greater expression of the oncoprotein stathmin 1 in ApcMin/+ mice and tyrosine phosphatase 4a2... inhibitory factor; Stmn1, stathmin 1; Ptp4a2, phosphatase ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
27 . Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org The Author 201 0 NG2-expressing glial precursor cells are a new potential oligodendroglioma cell
 

Summary:  environment can also initiate and mediate tumor growth, as nestin- positive neonatal neural progenitors... , Erlangen University, Germany), Nkx2.2 (mouse, 1/100e , Developmental Studies Hybridoma Bank), A2B5 (mouse... reduced to 1 hour each. Antibodies for cell surface markers, such as ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
28 Copyright 0 1996 by the Genetics Society of America Moml is a Semi-Dominant Modifierof Intestinal Adenoma Size
 

Summary:  -dominant fashion. The average size of tumors from the largeintes- 40,iA 2 35- 0 5 30- % 25- 4-a L 2 20- a, z' 15... - .. 'OI5 .: : : .; ..3 ..b 5.0 4.5j h 3.5- E 3.0- a, .$ 2.5- 8 2.0- sI- 1.5- 1.0- 0.5- .......... .: ::A I... of age. The effect of Moml on tumor ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
29 Gene expression profiling of human adrenocortical tumors using cDNA microarrays identifies several candidate genes
 

Summary:  -hydroxylase), CYP21A2 (steroid 21-hydroxylase), CYP17 (steroid 17-hydroxylase). It also contains PPM1A (protein... .3 CYP21A2 Cytochrome P450 c21; steroid 21-hydroxylase 6p21.1 HSD3B1 3ß-hydroxysteroid dehydrogenase... 1 Gene expression profiling of human adrenocortical tumors using cDNA ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
30 The Great Escape: When Cancer Cells Hijack the
 

Summary:  Ier3 Immediate early response 3 4.9 Ubl1a2 Ubiquitin-like 1 (sentrin) activating enzyme subunit 2 4... and nonmetastatic tumor cells (Shestakova et al. 1999). Disruption of ZBP1- mediated -actin mRNA targeting... -based intravital imaging, the chemotaxis-mediated collection of invasive ...

  

Source: Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
31 Drug Delivery with Carbon Nanotubes for In vivo Cancer Treatment Zhuang Liu,
 

Summary:  -PTX(3 H) at 30 min (A), 2 h (B), and 24 h (C) after injection. SWNT biodistribution was measured... promise in tumor-targeted accumulation in mice and exhibit biocompatibility, excretion, and little... toxicity. Here, we show in vivo SWNT drug delivery for tumor suppression in mice. We conjugate paclitaxel

  

Source: Dai, Hongjie - Department of Chemistry, Stanford University

 

Collection: Chemistry

 
32 Introduction Enhanced delivery of chemotherapeutic
 

Summary:  in electrochemotherapy with bleomycin or cisplatin, potentially mediated by tumor blood flow reduction, and enhanced... Introduction Enhanced delivery of chemotherapeutic drugs into tumor cells by electroporation... of tumor nodules to electric pulses (electroporation), results in increased Radiol Oncol 2003; ...

  

Source: Ljubljana, University of - Faculty of Electrical Engineering, Laboratory of Biocybernetics

 

Collection: Engineering ; Biology and Medicine

 
33 doi:10.1016/j.ijrobp.2004.09.018 BIOLOGY CONTRIBUTION
 

Summary:  with a caliper, and tumor volumes were calculated using the formula: V a2 b/2, where a was the shortest tumor... mediated apoptosis. Exp Cell Res 2000; 25:144­155. 6. Li CJ, Li YZ, Pinto AV. Potent inhibition of tumor... and Materials: FSaII ...

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine

 
34 The B7 Family and Cancer Therapy: Costimulation and Coinhibition Xingxing Zang andJames P. Allison
 

Summary:  and sarcoma tumors. Induction of B7-1 expression on tumors by transfection was sufficient to induce CD8 T cell­mediated... , 19 patients were vaccinated with an adenocarcinoma line transfected with B7-1 and HLA-A1 or A2... immune responses to a level that could ...

  

Source: Zang, Xingxing - Department of Microbiology and Immunology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
35 Statistical approach for detection and localization of a fluorescing mouse tumor in Intralipid
 

Summary:  x , (A2) fi z 2(ai bi) ai z bi z , (A3) ai x (x xsi )ai(ra 2 kra 1 ), (A4) ai z (z zsi )ai(ra 2 kra... Statistical approach for detection and localization of a fluorescing mouse tumor in Intralipid Adam... a method for detecting and localizing a fluorescing tumor obscured underneath several millimeters

  

Source: Bouman, Charles A.- School of Electrical and Computer Engineering, Purdue University

 

Collection: Engineering

 
36 Clinical Studies Oncolytic Adenovirus Coding for Granulocyte Macrophage
 

Summary:  -stimulating factor (GMCSF) can mediate antitumor effects by recruiting natural killer cells and by induction of tumor... in HLA-A2­positive patients Engineering an Oncolytic Adenovirus Coding for GMCSF Cancer Res; 70(11) June... and the associated im- munosuppressive tumor environment ...

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
37 Boyault et al, HEP 06-0968 revised 1 Transcriptome classification of HCC is related to gene alterations and to
 

Summary:  factor EEF1A2 and the enterokinase PRSS7, specifically over-expressed in PIK3CA mutated tumors using QRT... -Wallis test are indicated. b. Validation of EEF1A2 and PRSS7 genes over-expressed in PIK3CA mutated tumors... classification Key Words: ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
38 A quantitative theory of solid tumor growth, metabolic rate and vascularization
 

Summary:  . Figs. 2a, 2b show data from various tumors, indicating that tumor vasculature does indeed exhibit... 1 A quantitative theory of solid tumor growth, metabolic rate and vascularization Alexander B... .herman@ucsf.edu Abstract The relationships between cellular, structural and dynamical ...

  

Source: Santa Fe Institute

 

Collection: Multidisciplinary Databases and Resources

 
39 A Multiscale Approach for Computational Modeling of Biobarriers to Cancer
 

Summary:  diffu- sion coefficient into Deff = a2 w2 m/ 48Dm + Dm, thus incor- porating the contribution... are introduced [56]: = lDm a2w0 8Lp = p0 - i p1 - i (3) where l is the length of the capillary, w0 is the mean... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.1. ...

  

Source: Cristini, Vittorio - Departments of Biomedical Engineering & Mathematics, University of California, Irvine

 

Collection: Mathematics ; Engineering

 
40 Aim of the thesis Aim of the thesis
 

Summary:  strategies include correction or replacement of tumor suppressor genes, ablation or down regulation... of oncogenes, and or stimulation of immune system to eradicate tumor growth. Most of these strategies are based... on direct inhibition of tumor cells. Although these strategies showed therapeutic effect in pre

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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41 How molecular imaging is speeding up antiangiogenic drug development
 

Summary:  angiogenesis, such as a1h1, a2h1, a4h1, a5h1, a6h4, aIIbh3, and avh5 (32). Among all 24 integrins discovered... , predominant renal excretion, significant receptor-mediated tumor uptake, and good contrast in xenograft... in tumor angiogenesis imaging, and the targets include vascular ...

  

Source: Rao, Jianghong - Department of Radiology, Stanford University

 

Collection: Biology and Medicine

 
42 School of Life Sciences School of Engineering IBI Institute of Bioengineering / Institut de bioingnierie
 

Summary:  . These results provide evidence that lipoxygenase serves as a mediator of tumor cell invasion into lymphatic... and their matching axillary lymph nodes, we show here that intrametastatic lymphatic vessels and bulk tumor cell... model of tumor bulk invasion, human mammary carcinoma cells caused circular ...

  

Source: Floreano, Dario - Laboratory of Intelligent Systems, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Computer Technologies and Information Sciences ; Engineering

 
43 IOP PUBLISHING PHYSICS IN MEDICINE AND BIOLOGY Phys. Med. Biol. 54 (2009) 745755 doi:10.1088/0031-9155/54/3/018
 

Summary:  t ) + xb(t b ))/2. The true midpoint of a tumor's motion is given by xm = x0 + A/2. The shift in midpoint... displacement is xc = A/2. In the situation described above, no length distortion is present. However, since xt... positions of the tumor and organs. This ...

  

Source: Bewley, Thomas - Department of Mechanical and Aerospace Engineering, University of California at San Diego

 

Collection: Engineering

 
44 Revised for Cancer Research 4/20/2009 Published in final edited form as
 

Summary:  of the Mom1 locus, which encodes the secretory phopholipase A2 (19). Here too, the majority of tumors in (SWR... mutations or epigenetic alterations necessary for tumor progression. To overcome this limitation, we... developed few intestinal tumors and often lived longer than 1 year. ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
45 ORIGINAL RESEARCH Open Access Syndecan-1 antigen, a promising new target for
 

Summary:  ]. This mAb recognizes the CMH-peptide complex formed by peptide MAGE3 271-279 and HLA-A2. This epitope... by direct measurement of HLA-A2/Mage3 complex density using a high-affinity TCR like monoclonal antibody... cancer immuno-PET and radioimmunotherapy. A preclinical study on MDA-MB-468 xenograft ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
46 PRECLINICAL STUDY Prediction of lymph node involvement in breast cancer
 

Summary:  , ZNF385A, ZNF750, ZNF768 C21orf57, ERI2/EXOD1, MAN2A2, MYRIP, NR5A2, PDE5A, PEX12, RNF43, RPAIN, SORBS2... PRECLINICAL STUDY Prediction of lymph node involvement in breast cancer from primary tumor tissue... tumor. For this purpose, we selected a very homogeneous ...

  

Source: Leuven, Katholieke Universiteit, Department of Electrical Engineering, SCD Division

 

Collection: Engineering

 
47 Ovarian cancer gene therapy strategies Parameshwar J. Mahasreshti, Manjula Kataram, Ronald D.
 

Summary:  especially when the tumor burden was low (12). In another study, adenoviral-mediated in vivo p53 gene... , targeted eradication of human tumor cells. In this regard, adenovirus-mediated delivery of anti-erbB-2 s... to induce tumors in nu/nu mice (150). Liposome ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
48 An Oncolytic Adenoviral Vector of Smac Increases Antitumor Activity of TRAIL Against HCC
 

Summary:  for regulating apoptosis. Nat Cell Biol 2003;5:467­473. 17. Yang Q, Robin CH, Ren J, Newton ML, Du C. Omi/HtrA2... Cheng Qian,2 and Xinyuan Liu1 Hepatocellular carcinoma (HCC) displays a high resistance to tumor... necrosis factor­related apopto- sis­inducing ligand (TRAIL)­mediated cell death. To ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
49 Vol. 7, 1361-1368, October 1996 Cell Growth & Differentiation 1361 Action of Mm and Momi on Neoplasia in Ectopic Intestinal
 

Summary:  phospholipases, PIa2g2c and P1a2g5, have re- cently been shown to be tightly linked to PIa2g2a on distal mouse... . These conclusions would also apply to the two linked phospholipase genes, PIa2g2c and P1a2g5, if they are... ingested material, any effect of Pla2g2a on tumor multiplicity ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
50 Intestinal Adenomagenesis Involves Core Molecular Signatures of the Epithelial-Mesenchymal Transition
 

Summary:  (Figure 1A, 2C­F)? Truncated EMT may be important in tissue remodeling. Rapid proliferation leads... -cadherin decreased. Canonical E-cadherin suppressors, such as Snail, were not elevated in the same tumor. Elevated... . 2001), treatments are very ineffective against invasive and metastatic colonic tumors. ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
51 ORIGINAL ARTICLE Expression profile of skin papillomas with high cancer risk displays a
 

Summary:  - sis for microarrays; SCC, squamous cell carcinomas; TPA, 1B-50A 2-53D benign/papHigh benign... , University Park, PA, USA Chemical induction of squamous tumors in the mouse skin induces multiple benign... with SCC, while 1/10 clustered with low-risk papillomas, and this correlated with keratin markers of ...

  

Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
52 LIOBLASTOMAS multiforme (GBMs) are aggressive malignant tumors with the capacity to evade and
 

Summary:  experiments is mediated by the GM-CSF­enhanced abili- ty of antigen-presenting cells to present tumor... LIOBLASTOMAS multiforme (GBMs) are aggressive malignant tumors with the capacity to evade... and ultimately inhibit the body's mechanism for tumor defense.2,31,36 Epidemiologically, the peak incidence

  

Source: Low, Walter C. - Department of Integrative Biology and Physiology, University of Minnesota

 

Collection: Biology and Medicine

 
53 DISCRETE AND CONTINUOUS Website: http://AIMsciences.org DYNAMICAL SYSTEMSSERIES B
 

Summary:  . There are several parameters which mediate the tumor-host interactions described by equations (1-4). Where possible... . This paper describes mechanisms by which the cytokines IL-2 and TGF- mediate the immune response to tumor... . Paillard. Immunosuppression mediated by ...

  

Source: Kirschner, Denise - Department of Microbiology and Immunology, University of Michigan

 

Collection: Biology and Medicine

 
54 Three-dimensional multispecies nonlinear tumor growth--I Model and numerical method
 

Summary:  Three-dimensional multispecies nonlinear tumor growth--I Model and numerical method S.M. Wise a... continuum model of multispecies tumor growth and tumor-induced angiogenesis in two and three dimensions... . Three-dimensional simulations of nonlinear tumor growth and neovascularization using this diffuse

  

Source: Lowengrub, John - Department of Mathematics, University of California, Irvine

 

Collection: Mathematics

 
55 Z .Biochimica et Biophysica Acta 1332 1997 F25F48 Studies of neoplasia in the Min mouse 1
 

Summary:  tumor number but not tumor size in the w xlarge intestine 150 . Z .The secretory phospholipase A2 gene... . Shoemaker a,b , Karen A. Gould a,2,b , Cindy Luongo a,3,b , Amy R. Moser b,4 , William F. Dove a... 2g2a, phospholipase ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
56 Introduction Patients with breast carcinomas can display a different
 

Summary:  to physically interact with Skp2: cyclin A2, cyclin E1, Cdk2, and Cks1. In addition, markers of S... for estrogen receptor­positive (ER-pos- itive) and Her-2­overexpressing breast tumors, respec- tively. ER... different subtypes. These include Her- 2­positive as well as Her-2­negative tumors with a basal

  

Source: Roth, David B. - Langone Medical Center, New York University

 

Collection: Biology and Medicine

 
57 Mol Cancer Ther. Author manuscript Therapeutic efficacy of soluble receptor activator of nuclear factor-kappa
 

Summary:  therapeutic efficacy in restricting tumor-mediated osteolysis as well as in animal models of both bone... antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions. Cytokine... Osteosarcoma is the most frequent primary bone tumor that develops mainly during youth, the ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
58 PRECLINICAL STUDY Adult human mesenchymal stem cells enhance breast
 

Summary:  regulating increased turnover and proliferation of stromal cells in the tumor microenviron- ment may mediate... overall tumor volume. This increase in cell number indi- cates hMSC-mediated, enhanced proliferation... of the hormone-independent effect in the MCF-7/MSC tumors led us to ...

  

Source: McLachlan, John - Environmental Endocrinology Laboratory, Tulane University

 

Collection: Environmental Sciences and Ecology

 
59 Molecular Mechanisms of Liver Carcinogenesis in the Mdr2-Knockout Mice
 

Summary:  (encoding com- plement components), and cytochrome P450 genes Cyp1a2, Cyp2e1, Cyp4v3, Cyp8b1 (8, 25... of genome positions of differentially expressed genes in liver tumors revealed a prolonged region of down... -regulated genes on murine chromosome 8 in three of the six analyzed tumor samples. This region is ...

  

Source: Domany, Eytan - Physics of Complex Systems, Weizmann Institute of Science

 

Collection: Biology and Medicine ; Physics

 
60 DOI: 10.1126/science.1185837 , 749 (2010);328Science
 

Summary:  . In contrast, CCL21-deficient tumors induced antigen-specific immunity. CCL21-mediated immune tolerance... with CCR7- blocking antibodies (Fig. 1, C to H). Therefore, tumor-mediated, CCL21-dependent modulation... by Tumors That Express the Chemokine Induction of Lymphoidlike Stroma and Immune This copy is ...

  

Source: Floreano, Dario - Laboratory of Intelligent Systems, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Computer Technologies and Information Sciences ; Engineering


Page:   1  2  3  4  5 
Page:   1  2  3  4  5 
 
61 Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of
 

Summary:  protein 2 2.20E-06 3.92 ANGIO COL5A2 Collagen type V a 2 3.71E-05 3.72 ANGIO COL5A2 Collagen type V a 2 1... .94 LOWER SLCO1A2 Solute carrier organic anion transporter family member 1A2 4.46E-03 -2.06 LOWER PEA15... matrix ...

  

Source: Poirazi, Yiota - Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology, Hellas

 

Collection: Biology and Medicine

 
62 Ovarian Cancer Gene Therapy Parameshwar Janardhan Mahasreshti
 

Summary:  especially when the tumor burden was low (12). In another study, adenoviral-mediated in vivo p53 gene... , targeted eradication of human tumor cells. In this regard, adenovirus-mediated delivery of anti-erbB-2 s... to induce tumors in nu/nu mice (150). Liposome ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
63 BioMed Central Page 1 of 12
 

Summary:  pos 1.00 yes pos no 10b 2 pos pos 1.00 yes Unilateral tumor pairs that cluster 5a 2 3 neg neg 1.45 yes... pos 1.63 yes pos yes 9b" 3 pos pos 1.73 yes Bilateral tumor pairs that do not cluster 10a - 2 pos pos... .08 yes pos no 3b 1 pos pos 1.00 yes 4a§ ...

  

Source: Ringnér, Markus - Department of Theoretical Physics, Lunds Universitet

 

Collection: Physics ; Biotechnology

 
64 The role of ephrins and Eph receptors in cancer Hanna Surawska, Patrick C. Ma, Ravi Salgia*
 

Summary:  the receptor's role in p53-mediated tumor suppression, Dohn et al. produced exogenous EphA2-expressing cell... in tumor- igenesis and the Eph/ephrin axis. Dohn et al. [28] identified EphA2 and its ligand ephrin-A1... and surgically removed human ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
65 WEIGHTED NEIGHBORHOOD CLASSIFIER FOR THE CLASSIFICATION OF IMBALANCED TUMOR DATASET
 

Summary:  function, f : S Â ðG [ DÞ ! V , where V ¼ [a2G[DVa. Weighted Neighborhood Classi¯er for the Classi... : red //reduction of gene set 1: 8a 2 A, compute neighborhood relation Na; 2: red ¼ ; //red is the pool... WEIGHTED NEIGHBORHOOD CLASSIFIER FOR THE CLASSIFICATION OF IMBALANCED TUMOR ...

  

Source: Hefei Institute of Intelligent Machines - Intelligent Computing Lab

 

Collection: Computer Technologies and Information Sciences

 
66 Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas
 

Summary:  with the immune system, expressing tumor-asso- ciated antigens and becoming targets for T cell- mediated adaptive... that ovarian tumor development and progression may be associated with downregulation of T cell-mediated... a dual effect of enhanced T cell-mediated antitumor immunity ...

  

Source: Zang, Xingxing - Department of Microbiology and Immunology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
67 Cancer Therapy: Preclinical Targeted Radiotherapy for Prostate Cancer with an Oncolytic
 

Summary:  , the virus-mediated radioiodide uptake into prostate cancer cells in vitro and into tumors in vivo... NIS can mediate radioactive iodide uptake into prostate cancer tumors. Subcutaneous PC-3MM2 tumors were... /mouse). Iodide uptake was imaged (A) 2 ...

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
68 Current Biology 17, 431437, March 6, 2007 2007 Elsevier Ltd All rights reserved DOI 10.1016/j.cub.2007.01.049 A Virus Causes Cancer by Inducing
 

Summary:  (Figure 1A.2, ``DV'') by first infecting another aliquot of D551 cells with MPMVE , a primate retrovirus... in proteins, such as the tumor suppressor p53 [3­5], that police genome integrity, but the primary cause... onco- genes, adenoviral E1A, which deregulates the cell cycle by inactivating the tumor ...

  

Source: Russell, Gareth - Department of Biological Sciences, New Jersey Institute of Technology

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
69 Cancer Letters, 69 (1993) 81-84 81 Elsevier Scientific Publishers Ireland Ltd.
 

Summary:  of the association of radiolabeled bleomycin A2 with HeLa cells. Cancer. Res., 44, 1541-1546. 17 Sersa, G... Cicb "Department of Tumor Biology and Biotherapy, Institute of Oncology, ZaloSka 2, 61000 Ljubljana and b... ability to increase the responsiveness of murine tumors to bleomycin treatment. Mice bearing ...

  

Source: Ljubljana, University of - Faculty of Electrical Engineering, Laboratory of Biocybernetics

 

Collection: Engineering ; Biology and Medicine

 
70 The FASEB Journal Research Communication Identification of a myeloid-derived suppressor cell
 

Summary:  tumor invasion and metastasis. To iden- tify the mediator responsible for the prometastatic property... -like protein, NGP, in MDSCs negatively correlated to tumor metastasis To identify the molecular mediators... (20). Thus, the identification of molec- ular mediators in MDSCs relevant ...

  

Source: Bogyo, Matthew - Department of Microbiology and Immunology, Stanford University

 

Collection: Biology and Medicine

 
71 Abstract. Advancements in the diagnosis and prognosis of brain tumor patients, and thus in their survival and quality of
 

Summary:  symbol SLC22A2; CTL3, gene symbol SLC22A13; and CTL4, gene symbol SLC22A14) are either unchanged, or down... kinase · CHKA 1.26 NM_178034 Phospholipase A2, group IVD (cytosolic) PLA2G4D 1.23 NM_005017 Phosphate... _003058 Solute carrier family 22 (organic cation transporter), member 2 ...

  

Source: Galatsanos, Nikolas P. - Department of Computer Science, University of Ioannina

 

Collection: Computer Technologies and Information Sciences

 
72 Neu-Induced Retroviral Rat Mammary Carcinogenesis: A Novel Chemoprevention Model for Both Hormonally Responsive
 

Summary:  % (P < 0.0001) in experiments 1a, 2a, and 3a (Table 1), respectively. This reduction was amplified... -induced mammary carcinomas. Dietary LG100268 at 100 mg/kg diet decreased tumor multiplicity by 32% (P = 0... was associated with reductions in tumor multiplicity of 84% (P < 0.0001) and 86% (P < ...

  

Source: Gould, Michael N. - Molecular and Cellular Pharmacology Training Program & Department of Oncology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
73 BioMed Central Page 1 of 10
 

Summary:  .17 Angiotensinogen APOA2 5343.06 Apolipoprotein A-II Metastasis MGC16121 2032.63 - PLA2R1 1405.16 Phospholipase A2... /S2 Page 9 of 10 (page number not for citation purposes) (phospholipase A2 receptor 1, 1405... , Lambeau G, Marone G, Triggiani M: Activation of Cytokine Production by Secreted Phospholipase ...

  

Source: Lee, Doheon - Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology

 

Collection: Computer Technologies and Information Sciences ; Biotechnology

 
74 ORIGINAL ARTICLE Potent antitumor efficacy of XAF1 delivered by conditionally
 

Summary:  described to be able to execute cell death, including calpains, cathepsins B, D, L, Omi/HtrA2 and granzymes... model. In summary, the CRAd vector ZD55-mediated transfer of tumor-suppressor gene XAF1 displayed... of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China XAF1 is a newly ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
75 Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma
 

Summary:  areas (``N'' in B), multinucleated giant cells (C), and perivascular satellitosis (D). Scale bars: (A) 2... Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma Chong Liu,1 Jonathan C... cells within terminal stage tumors, whose identity could be concealed by the acquired plas- ticity. ...

  

Source: Luo, Liqun - Department of Biology, Stanford University

 

Collection: Biology and Medicine

 
76 DISCRETE AND CONTINUOUS Website: http://AIMsciences.org DYNAMICAL SYSTEMSSERIES B
 

Summary:  that (A2): For model (4.1), Pe fnkh < 1 and L > 1 at E . Clearly (A2) implies that Pe fmkh < 1... dt = -x(A1(x - x ) + A2(y - y ) + A3(z - z )), dy dt = -y(B1(x - x ) + B2(y - y ) + B3(z - z )), dz... > c/c2, 2): B2/c2 > B3 + B1/c1, 3): A1/c1 > A1 + ...

  

Source: Arizona State University - Integrated Research Challenges in Environmental Biology, Biological Stoichiometry Program; Kuang, Yang - Department of Mathematics and Statistics, Arizona State University

 

Collection: Environmental Sciences and Ecology ; Mathematics

 
77 Digital Object Identifier (DOI): 10.1007/s00285-003-0262-2
 

Summary:  Biology Nikos V. Mantzaris · Steve Webb · Hans G. Othmer Mathematical modeling of tumor... .1. Signaling From Tumor to Vessel at the Onset of Angiogenesis . . . . . . . . 3.1.1. Transforming Growth... or phrases: Review ­ Angiogenesis ­ Physiology ­ Mathematical modeling ­ Tumors #12;N. V. Mantzaris et al. 8

  

Source: Othmer, Hans - School of Mathematics, University of Minnesota

 

Collection: Mathematics

 
78 This is the author preprint version of an article accepted for publication by Carcinogenesis Carcinogenesis Advance Access published online on February 28, 2008
 

Summary:  ) Associations between polymorphisms in the steroid 5-alpha reductase type II (SRD5A2) gene and benign prostatic... and tumorigenesis in ApcMin mice Keywords: Hyperplasia, regionality, zinc, intestine, tumor, Apc #12;2 ABSTRACT... induced hyperplasia is sufficient to increase intestinal tumor multiplicity or ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
79 A Novel Cancer Vaccine Strategy Based on HLA-A*0201 Matched Allogeneic Plasmacytoid Dendritic Cells
 

Summary:  | Issue 5 | e10458 #12;Supporting Information Figure S1 HLA-A2 and tumor antigen expression by melanoma... tumor cell lines. (A) Analysis by flow cytometry of surface HLA-A2 (top panels) and intracellular Mel... . Anti-HLA-A2 ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
80 MOLECULAR AND CELLULAR BIOLOGY, Feb. 2003, p. 12691277 Vol. 23, No. 4 0270-7306/03/$08.00 0 DOI: 10.1128/MCB.23.4.12691277.2003
 

Summary:  d (40). Several observations suggest that p18INK4c may play a major role in mediating the tumor... null mice spontaneously developed pituitary inter- mediate lobe tumors ( 75%) (5, 6, 18) or, at a lower... with familial and sporadic melanoma in humans and result in a wide spectrum of ...

  

Source: Xiong, Yue - Lineberger Comprehensive Cancer Center & Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill

 

Collection: Biology and Medicine


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81 IOP PUBLISHING PHYSICAL BIOLOGY Phys. Biol. 5 (2008) 036010 (10pp) doi:10.1088/1478-3975/5/3/036010
 

Summary:  A validated mathematical model of cell-mediated immune response to tumor growth Cancer Res. 65 7950­8 [7... .1088/1478-3975/5/3/036010 Simulating tumor growth in confined heterogeneous environments Jana L Gevertz1, George T Gillies2... The holy grail of computational tumor modeling is to develop a simulation ...

  

Source: Torquato, Salvatore - Department of Chemical Engineering, Princeton University

 

Collection: Materials Science ; Chemistry

 
82 DNA tumor viruses and human cancer Blossom Damania
 

Summary:  mediated by latency- associated nuclear antigen. Science 284, 641­644 53 Cotter, M.A., 2nd and Robertson, E... DNA tumor viruses and human cancer Blossom Damania Lineberger Comprehensive Cancer Center, CB #7295... and there are indications that cofactors could be required for viral oncogenicity in some ...

  

Source: Damania, Blossom - Department of Microbiology and Immunology, University of North Carolina at Chapel Hill

 

Collection: Biology and Medicine

 
83 Genome-Wide Expression Profiling Reveals EBV-Associated Inhibition of MHC Class I Expression in
 

Summary:  for their ability to sustain higher levels of EBV to take maximum advantage of EBV oncogene- mediated tumor... the HLA-A2 subtype, prevalent among Chinese (5), but the mechanism of increased susceptibility is unknown... class I­mediated antigen presentation. Materials and Methods NPC ...

  

Source: Newton, Michael - Departments of Statistics & Biostatistics and Medical Informatics, University of Wisconsin at Madison

 

Collection: Biology and Medicine ; Mathematics

 
84 IL-12 Treatment of Endogenously Arising Murine Brain Edward J. Roy,2
 

Summary:  by IL-12 could contribute to the T cell-mediated anti-tumor effect (6). Finally, the anti-tumor activity... T cell-mediated responses against CNS tumors to which the immune system is tolerant or ignorant (14, 15... in IL-12- mediated rejection of ...

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
85 Ovarian cancer is the most lethal cause of death among the gynecological cancers. Conventional therapies of surgery and chemotherapy failed to significantly improve the survival rates for this disease. Therefore
 

Summary:  delivery of genes to tumor tissues such as transductional targeting and transcriptional targeting are also... overexpression is correlated with increased tumor growth, ascites fluid accumulation, metastases, poor prognosis... angiogenesis by antagonizing VEGF is employed for ovarian cancer gene therapy to inhibit tumor ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
86 Cooperative nanomaterial system to sensitize, target, and treat tumors
 

Summary:  - MB-435 tumors, less significant changes in the level of heat- mediated p32 expression were observed... ). Similarly, the increased temperature in the tumor produced by NR-mediated photothermal heating slows tumor... of DOX in tumors as a function of ...

  

Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biotechnology ; Biology and Medicine

 
87 The major themes of our research projects are the roles of growth factors and proteolytic enzymes in tissue remodeling, in particular tumor invasion and blood vessel formation (angiogenesis).
 

Summary:  in tissue remodeling, in particular tumor invasion and blood vessel formation (angiogenesis). Growth Factor... , is required for the growth and metastasis of solid tumors. A number of cytokines and growth factors induce... angiogenesis. Among them vascular endothelial growth factor (VEGF) has been implicated as the major tumor

  

Source: Wang, Da-Neng - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University

 

Collection: Biology and Medicine

 
88 Inducing a mode of NK-resistance to suppression by stress and surgery: A potential approach based on low dose of poly IC
 

Summary:  , the coefficient of variation for this method was 6% for identical samples (Ben-Eliyahu et al., 1999a). 2... or to undergo surgery 10 h after the third poly I­C injection (a 2 · 2 design). All rats housed in a cage were... resistance to tumor progression. Here, we sought to develop a ...

  

Source: Shakhar, Guy - Department of Immunology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
89 *Corresponding author J. Math. Biol. (1998) 37: 235--252
 

Summary:  of the tumor ­ immune interaction Denise Kirschner, John Carl Panetta* Department of Microbiology... tumors. CD4> T cells, the cells that orchestrate the immune response, use these cytokines as signaling... . Because tumor cells begin as `self', the immune system may not respond in an effective way to eradicate

  

Source: Kirschner, Denise - Department of Microbiology and Immunology, University of Michigan

 

Collection: Biology and Medicine

 
90 Proc. Natl. Acad. Sci. USA Vol. 95, pp. 1082610831, September 1998
 

Summary:  back- ground. Somatic treatment with a strong mutagen increases tumor number in AKR Min mice in an age... that Apc ex- pression is suppressed in all intestinal tumors from both untreated and treated AKR Min mice... mice. Although loss of heterozygosity is observed in some tumors, a significant percentage of ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
91 EVIDENCE THAT STRESS AND SURGICAL INTERVENTIONS PROMOTE TUMOR DEVELOPMENT BY SUPPRESSING NATURAL KILLER CELL ACTIVITY
 

Summary:  tumor development. Under certain stressful conditions, suppression of NKA is the pri- mary mediator... the relative importance of stress-induced suppression of NKA in mediating the effects of stress on tumor... was to assess the specific role of NK cells in mediating the effects of ...

  

Source: Shakhar, Guy - Department of Immunology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
92 Modeling the Effect of Chemotaxis on Glioblastoma Tumor Progression
 

Summary:  Modeling the Effect of Chemotaxis on Glioblastoma Tumor Progression Francisco G. Vital... .1002/aic.12296 Published online June 22, 2010 in Wiley Online Library (wileyonlinelibrary.com). Tumor... -dimensional) progression of a brain tumor type (i.e., glioblastoma multiforme) as the collective behavior of individual

  

Source: Maranas, Costas - Department of Chemical Engineering, Pennsylvania State University

 

Collection: Engineering ; Biotechnology

 
93 B Academy of Molecular Imaging and Society for Molecular Imaging, 2010 Published Online: 23 December 2010 DOI: 10.1007/s11307-010-0457-z
 

Summary:  RJ (2006) Acid- mediated tumor invasion: a multidisciplinary study. Cancer Res 66:5216­5223 5... Measuring Tumor Aggressiveness and Targeting Metastatic Lesions with Fluorescent pHLIP Yana K. Reshetnyak,1... after transmembrane insertion. Results: We demonstrate that pHLIP targets: (a) tumors of different

  

Source: Rhode Island, University of - Department of Physics, Division of Biological and Medical Physics

 

Collection: Biology and Medicine

 
94 B Academy of Molecular Imaging and Society for Molecular Imaging, 2010 DOI: 10.1007/s11307-010-0457-z
 

Summary:  RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ (2006) Acid- mediated tumor invasion... -010-0457-z Mol Imaging Biol (2010) RESEARCH ARTICLE Measuring Tumor Aggressiveness and Targeting Metastatic... that pHLIP targets: (a) tumors of different origins established by subcutaneous injection of cancer cells

  

Source: Engelman, Donald M.- Department of Molecular Biophysics and Biochemistry, Yale University; Rhode Island, University of - Department of Physics, Division of Biological and Medical Physics

 

Collection: Biology and Medicine

 
95 Fas ligandmediated paracrine T cell regulation by the receptor NKG2D in tumor immunity
 

Summary:  , the ovarian tumor­derived CD4+ T cell clones 23 and 55 and the HLA-A2-restricted and MART-1-specific CD8... and the OT140 ovarian tumor line were grown as described7,24. C1R­MICA*001, C1R­MICA*004, C1R­HLA-A2 and C1R­HLA-A... Fas ...

  

Source: Spies, Thomas - Basic Sciences Division, Fred Hutchinson Cancer Research Center

 

Collection: Biology and Medicine

 
96 ELECfRO-AND MAGNETOBIOLOGY, 17(2),273-282 (1998) BLOOD PERFUSION IN A MURINE
 

Summary:  AFTER ELECTROTHERAPY 7 6 5 4 g ~ Q ~ 3 0c. f- a:: 2 ··· ·1 · ·0 ·ET\ -I 0 (A) 7 6 5 0 ~ 4 · ~~ ·:!!.0 3... ~ · 0c. f- a:: 2 ·· 0 ~." ETI -I 0 (B) 0 · e0 0 · I · ·· 2 3 4 24 Time after ET (hours) · · · ~ I ~ · 2... ELECfRO- AND MAGNETOBIOLOGY, 17(2),273-282 (1998) BLOOD PERFUSION IN A ...

  

Source: Ljubljana, University of - Faculty of Electrical Engineering, Laboratory of Biocybernetics

 

Collection: Engineering ; Biology and Medicine

 
97 Mnard. Reptin silencing blocks liver cancer progression 1 In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in
 

Summary:  -33076 Bordeaux, France; 4 Université de Bordeaux, Animalerie A2, F-33076 Bordeaux, France Note : * LM... arrest and apoptosis. We asked whether in vivo targeting of Reptin in established tumors had... subcutaneously into immunodeficient mice and Dox was given when tumors reached a volume of 250 mm3 . ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
98 Longitudinal Assessment of Colonic Tumor Fate in Mice by Computed Tomography and Optical Colonoscopy
 

Summary:  -zero treatment effect = (b,2 ­ a,2) - (b,1­ a,1). A balanced longitudinal design in which a total of L animals... 1 Longitudinal Assessment of Colonic Tumor Fate in Mice by Computed Tomography and Optical... studies of colonic tumors in mice. Materials and Methods: Colonic tumors in ...

  

Source: Dove, William - McArdle Laboratory for Cancer & Department of Medical Genetics, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
99 Journal of the Korean Physical Society, Vol. 49, No. 4, October 2006, pp. 16521666 A Stochastic Model of Cancer Growth with Immune Response
 

Summary:  a system of kinetic equations for cell growth and cell-mediated cytolysis in tumors composed of a two- step... reaction for the kinetics of cell-mediated cytolysis in tumors. This reaction led only to the tumor... equations for the growth and cell- mediated cytolysis ...

  

Source: Wong-Ekkabut, Jirasak - Department of Physics, Kasetsart University

 

Collection: Materials Science ; Biology and Medicine

 
100 The Transcription Factor REST Is Lost in Aggressive Breast Cancer
 

Summary:  of the tumor suppressor RE1 silencing transcription factor (REST) is lost in colon and small cell lung cancers... is currently known about the role of this tumor suppressor in breast cancer. Here, we test the hypothesis... that loss of REST function plays a role in breast cancer. To assay breast tumors for REST function, we

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine


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