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Sample search results for: a2b1 integrin transgenic

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1 Corneal integrins and their functions Mary Ann Stepp*
 

Summary:  - gens. a1b1 and a2b1 are often referred to as the canonical integrin collagen receptors. The corneal... , and a3b1. In their experiments they did not look at a2b1 or at other av-containing ...

  

Source: Moody, Sally A. - Department of Anatomy and Cell Biology, George Washington University

 

Collection: Biology and Medicine

 
2 Integrin avidity regulation: are changes in affinity and conformation underemphasized?
 

Summary:  , Liddington RC: Structural basis of collagen recognition by integrin a2b1. Cell 2000, 101:47-56. 18. Lee J... Integrin avidity regulation: are changes in affinity and conformation underemphasized? Opinion... Christopher V Carman and Timothy A Springer ...

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
3 Cardiac MyocyteSpecific Excision of the 1 Integrin Gene Results in Myocardial Fibrosis and Cardiac Failure
 

Summary:  ventricular myocytes and also that dominant-negative disruption of integrin func- tion in transgenic mice... Cardiac Myocyte­Specific Excision of the 1 Integrin Gene Results in Myocardial Fibrosis and Cardiac... , Joseph C. Loftus, Robert S. Ross Abstract--Integrins link the extracellular matrix to the ...

  

Source: Smith, Desmond J. - Department of Molecular and Medical Pharmacology, University of California at Los Angeles

 

Collection: Biology and Medicine

 
4 Brief Communications 6 4 Integrin and Dystroglycan Cooperate to Stabilize the
 

Summary:  Brief Communications 6 4 Integrin and Dystroglycan Cooperate to Stabilize the Myelin Sheath... integrate signals deriving from the axon and the basal lamina to myelinate peripheral nerves. Integrin 6 4... is a laminin receptor synthesized by Schwann cells and displayed apposed to the basal lamina. 6 4 integrin

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
5 PATTERNS & PHENOTYPES Regional Distribution of 9 1 Integrin Within the
 

Summary:  PATTERNS & PHENOTYPES Regional Distribution of 9 1 Integrin Within the Limbus of the Mouse Ocular... contain different numbers of 9 integrin­positive cells most of which are observed in the nasal region. We... confocal images obtained after tissues were dual stained with 9 integrin and propidium iodide (PI

  

Source: Moody, Sally A. - Department of Anatomy and Cell Biology, George Washington University

 

Collection: Biology and Medicine

 
6 David Lesniak Department of Oncology
 

Summary:  , Kurpios NA, Zuo D, et al. Targeted disrup- tion of 1-integrin in a transgenic mouse model of hu- man... to this use this knowledge as an active clinician scientist. #12;Clinical Research 1-Integrin Circumvents... biomarker for selecting patients for trastuzumab-based ther- apy. 1-Integrin, an adhesion ...

  

Source: MacMillan, Andrew - Department of Biochemistry, University of Alberta

 

Collection: Chemistry ; Biology and Medicine

 
7 Development/Plasticity/Repair Distinct Roles of the 1-Class Integrins at the Developing
 

Summary:  ), respectively. The cre transgenes were introduced into mice heterozygous for the 1 integrin null and conditional... Development/Plasticity/Repair Distinct Roles of the 1-Class Integrins at the Developing... Disease, La Jolla, California 92037 Integrins are a large family of cell adhesion receptors involved

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
8 Expression Patterns of Focal Adhesion Associated Proteins in the Developing Retina
 

Summary:  induced by transgenic integrin expression. J Neurosci 21:4782­4788. Condic ML, Letourneau PC. 1997. Ligand... ABSTRACT Adhesive interactions between integrin receptors and the extracellular matrix (ECM) are intimately... have investigated the re- lationships between 1 integrin receptors and fo- cal adhesion ...

  

Source: Sakaguchi, Donald S. - Department of Genetics, Development and Cell Biology, Iowa State University

 

Collection: Biology and Medicine

 
9 Integrin Dependence of Calu-1 Cell Motility on Endothelial Extracellular Matrix Proteins
 

Summary:  lines. These data support the hypothesis that integrins a2b1, a3b1, and a6b1 are responsible... of the Calu-1 cells on laminin requires at least one of the three integrins: a2b1, a3b1, ...

  

Source: Zhu, Cheng - Department of Biomedical Engineering, Georgia Institute of Technology and Emory University

 

Collection: Engineering ; Biology and Medicine

 
10 Integrin 1 Regulates Phagosome Maturation in Macrophages through Rac Expression1
 

Summary:  specifically in macrophages by crossing mice with floxed integrin 1 alleles (20) to transgenic mice expressing... ). To generate 1 integrin-deficient mac- rophages, CD29f/f mice were crossed with LysM-Cre transgenic mice (21... , we crossed CD29f/f mice with LysM-Cre transgenic mice to ...

  

Source: Rockey, Don - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
11 www.sciencemag.org SCIENCE VOL 319 11 JANUARY 2008 137 EDITORS'CHOICE
 

Summary:  proteins. Integrins are subunit receptors located in the plasma membrane and link the extracellular matrix... to the intracellular cytoskeleton. Belvindrah et al. have taken a closer look at how 1 integrin contributes... and migrating neurons were deficient in 1 integrin, and compared it with a mouse line they developed

  

Source: Kim, Ho-Young - School of Mechanical and Aerospace Engineering, Seoul National University

 

Collection: Engineering ; Materials Science

 
12 A Mouse Model for the Study of Recurrent Corneal Epithelial Erosions: 9 1 Integrin Implicated in
 

Summary:  A Mouse Model for the Study of Recurrent Corneal Epithelial Erosions: 9 1 Integrin Implicated... ) in mice and to characterize the changes in 9 integrin expression during wound healing. METHODS. Corneal... and stained with propidium iodide and an antibody against 9 integrin or for bromodeoxyuridine analyses of cell

  

Source: Moody, Sally A. - Department of Anatomy and Cell Biology, George Washington University

 

Collection: Biology and Medicine

 
13 Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells
 

Summary:  . Transgenic expression of a dominant-negative 1 integrin or ablation of the 1 integrin gene in mammary luminal... ;10. White DE Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer... Beta1 integrin deletion from the basal ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
14 Integrins 1, 6, and 3 contribute to mechanical strain-induced differentiation of fetal lung type II epithelial cells via distinct mechanisms
 

Summary:  Integrins 1, 6, and 3 contribute to mechanical strain-induced differentiation of fetal lung type II... , Lewis P. Rubin, and Donald E. Ingber. Integrins 1, 6, and 3 contribute to mechanical strain... antibodies against integrin 1, 3, or 6. Additional studies were carried out with substrates coated directly

  

Source: Ingber, Donald E. - Vascular Biology Program, Harvard University

 

Collection: Biology and Medicine

 
15 Junichi Takagi Integrin activation and structural Timothy A. Springer
 

Summary:  Junichi Takagi Integrin activation and structural Timothy A. Springer rearrangement Authors... -2896 141 Summary: Among adhesion receptor families, integrins are particularly important in biological... integrins on leukocytes and b3 integrins on platelets enables deposition of these cells at sites

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
16 INTRODUCTION Molecular mechanisms mediating the initial establishment and
 

Summary:  and synaptic localization of FAS2. Synaptic structural defects in PS integrin mutants are rescued by transgenic... ), immunoglobin superfamily cell adhesion molecule Fasciclin 2 (FAS2) and the position specific (PS) integrin... development and that this role is regulated by activation of CaMKII. We show that PS ...

  

Source: Broadie, Kendal S. - Department of Biological Sciences, Vanderbilt University

 

Collection: Biology and Medicine

 
17 INTRODUCTION Integrins have long been known to participate in embryonic
 

Summary:  expression or transgenic PS constructs reveal that integrins impact morphological growth, synaptic... INTRODUCTION Integrins have long been known to participate in embryonic neurogenesis. Integrin... of synaptic arbors (Chiba and Keshishian, 1996; Martin et al., 1996). In recent years, ...

  

Source: Broadie, Kendal S. - Department of Biological Sciences, Vanderbilt University

 

Collection: Biology and Medicine

 
18 (Article publi dans FEBS Letters, (2005); 579: 1079-1084.) Alpha7 Beta1 Integrin changes in mdx mouse muscles after L-arginine
 

Summary:  (Article publié dans FEBS Letters, (2005); 579: 1079-1084.) Alpha7 Beta1 Integrin changes in mdx... mechanisms, i.e., dystrophin with its associated proteins and 71 integrin. In humans, gene-mutation defects... -arginine treatment of utrophin-associated proteins and the 71 integrin subunit in mdx mouse, a dystrophin

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
19 Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila
 

Summary:  Integrin-independent repression of cadherin transcription by talin during axis formation... integrins to the actin cytoskeleton, has the unexpected function of specifically inhibiting DE- Cadherin... of talin is independent of integrins. These results uncover a novel role for talin in regulating cadherin

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
20 Current Biology, Vol. 13, 922932, May 27, 2003, 2003 Elsevier Science Ltd. All rights reserved. DOI 10.1016/S0960-9822(03)00372-5 C. elegans PAT-6/Actopaxin Plays a Critical Role
 

Summary:  , we introduced the samefrom UNC-52, PAT-3/integrin, UNC-112, and PAT-4/ILK transgenic constructs... of Integrin Adhesion Complexes In Vivo functions, including the relatively recent discovery that signaling... of this important class of integrin-mediated at-Vancouver, British Columbia Canada V6T 1Z4 ...

  

Source: Moerman, Donald G. - Department of Zoology, University of British Columbia

 

Collection: Biology and Medicine


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21 1 Integrin Deletion from the Basal Compartment of the Mammary Epithelium Affects Stem Cells
 

Summary:  population has not been addressed yet. Transgenic expression of a dominant-negative 1 integrin or ablation... of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary... 1 1 Integrin Deletion from the Basal Compartment of the Mammary ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
22 Transgenic crop species have been adopted by a growing number of countries in the past decade,and the
 

Summary:  the frequencies of the four possible gamete types A1 B1 , A1 B2 , A2 B1 , and A2 B2 as x1 , x2 , x3 , and x4... Forum Transgenic crop species have been adopted by a growing number of countries in the past decade... ,and the acreage devoted to transgenic species has ...

  

Source: Schoen, Daniel - Department of Biology, McGill University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
23 Neuron, Vol. 31, 367379, August 16, 2001, Copyright 2001 by Cell Press 1-Class Integrins Regulate the
 

Summary:  Neuron, Vol. 31, 367­379, August 16, 2001, Copyright 2001 by Cell Press 1-Class Integrins Regulate... of a common 1 subunit with different subunits. 1-classMice that lack all 1-class integrins in neurons... and integrins interact with ECM molecules and cell surfaceglia die prematurely after birth with severe brain mal

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
24 Current Biology, Vol. 12, 787797, May 14, 2002, 2002 Elsevier Science Ltd. All rights reserved. PII S0960-9822(02)00810-2 C. elegans PAT-4/ILK Functions as an Adaptor
 

Summary:  . PAT-4/ILK Colocalizes with Integrin Transgenic minigenes encoding translational fusions between PAT-4... . PII S0960-9822(02)00810-2 C. elegans PAT-4/ILK Functions as an Adaptor Protein within Integrin... Vancouver, British Columbia V6T 1Z4 pat-4, which we show codes for the nematode homologCanada of integrin

  

Source: Moerman, Donald G. - Department of Zoology, University of British Columbia

 

Collection: Biology and Medicine

 
25 The initial steps of myofibril assembly: integrins pave the way
 

Summary:  opinion The initial steps of myofibril assembly: integrins pave the way John C. Sparrow and Frieder... that set sarcomere spacing and the initial assembly of sarcomere arrays. We propose a model of integrin... -to-end at intercalated discs in cardiac muscle. Heterodimeric integrins, which connect thin filaments to ECM ligands

  

Source: Schoeck, Frieder - Department of Biology, McGill University

 

Collection: Biology and Medicine

 
26 The Rockefeller University Press, 0021-9525/2000/07/253/12 $5.00 The Journal of Cell Biology, Volume 150, Number 1, July 10, 2000 253264
 

Summary:  elegans Encodes a Novel Component of Cell­Matrix Adhesion Structures Required for Integrin Localization... to assemble. The unc-52 (perlecan), pat-2 ( -integrin), and pat-3 ( -integrin) genes encode ECM... protein that colocalizes with integrin at cell­matrix ad- hesion complexes.The 720­amino acid ...

  

Source: Moerman, Donald G. - Department of Zoology, University of British Columbia

 

Collection: Biology and Medicine

 
27 DEVELOPMENT 2383RESEARCH ARTICLE
 

Summary:  (Fig. Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches... that links integrins to the cytoskeleton. Terminal cells mutant for myospheroid, the major Drosophila... -integrin, or doubly mutant for multiple edematous wings and inflated -integrins, also show the ...

  

Source: Krasnow, Mark A. - Department of Biochemistry, Stanford University

 

Collection: Biology and Medicine

 
28 The Journal of Clinical Investigation http://www.jci.org Volume 117 Number 9 September 2007 Eun Jeong Park,1,2 J. Rodrigo Mora,1,3,4 Christopher V. Carman,5 JianFeng Chen,1,3
 

Summary:  Medical School, Boston, Massachusetts, USA. Integrin adhesion molecules mediate lymphocyte migration... and homing to normal and inflamed tissues. While the ligand-binding activity of integrins is known... to be modulated by conformational changes, little is known about how the appropriate balance of integrin

  

Source: von Andrian, Ulrich H. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
29 DEMYSTIFICATION OF INTEGRIN ACTIVATION MECHANISM Steven Sligar, Department of Chemistry, University of Illinois, UrbanaChampaign
 

Summary:  DEMYSTIFICATION OF INTEGRIN ACTIVATION MECHANISM Steven Sligar, Department of Chemistry... . Sligar, K. Taylor, and M. Ginsberg. J. Cell Biol., 2009, 188 (1), 157­173. Integrins are proteins... . Genetic studies have indicated that integrin is activated by the proteins talin and kindlin

  

Source: Shull, Kenneth R. - Department of Materials Science and Engineering, Northwestern University

 

Collection: Materials Science

 
30 2032 Research Article Introduction
 

Summary:  the cell. We also show that secreted epimorphin binds to v-integrin-containing receptors on target... : Epimorphin, Integrin, Morphogenesis, Membrane translocation, t-SNARE Summary Non-classical export... of epimorphin and its adhesion to v-integrin in regulation of epithelial morphogenesis Yohei Hirai1, *, Celeste

  

Source: Nelson, Celeste M. - Departments of Molecular Biology & Chemical Engineering, Princeton University

 

Collection: Biology and Medicine ; Biotechnology

 
31 Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Regulates Neuromuscular Junction Development
 

Summary:  a b1 Integrin-Mediated Mechanism Gentian Lluri,1 Garret D. Langlois,1 Brian McClellan,1 Paul D... reduced in TIMP-22//2 EDL. We propose that reduced b1 integrin in fast- twitch muscle may be associated... : costamere; integrin; knockout; mechano- transduction; myogenesis; proMMP-2 INTRODUCTION Muscle contraction

  

Source: Jaworski, Diane - Department of Anatomy and Neurobiology, University of Vermont

 

Collection: Biology and Medicine

 
32 Development. Author manuscript Defective osteoblast function in ICAP-1-deficient mice
 

Summary:  .bouvard@ujf-grenoble.fr> Abstract SUMMARY The integrin receptor family plays important roles in cell-to-cell and cell... -to-extracellular matrix (ECM) interactions through the recruitment of accessory molecules. One of them is the integrin... of integrin subunit and negatively regulates its function in vitro. To address the ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
33 Osteoblast mineralization requires 1 integrin/ICAP-1-dependent fibronectin deposition
 

Summary:  1 Osteoblast mineralization requires 1 integrin/ICAP-1-dependent fibronectin deposition Running... to 1 integrin to control dynamics of fibrillar adhesion sites, fibronectin deposition, and osteoblast... .albigesrizo@ujfgrenoble.fr # Both authors equally contributed to the work Characters counts: 40000 Key words : integrin, ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
34 Structure of an integrin with an aI domain, complement receptor type 4
 

Summary:  Structure of an integrin with an aI domain, complement receptor type 4 Can Xie1 , Jianghai Zhu1... of an integrin with an aI domain, aXb2, the complement receptor type 4. It was earlier expected that a fixed... . Although aXb2 is bent similarly to integrins that lack aI domains, the terminal domains of the a- and b

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
35 2851Research Article Introduction
 

Summary:  shown to interact with integrins at focal adhesions during wound healing (Alexopoulou et al., 2007... integrins in various cancer cell lines (Beauvais et al., 2004; Beauvais and Rapraeger, 2004; McQuade et al... with antibodies that block 6 or v integrin function, or with TGF 1. Antagonizing either 1 ...

  

Source: Moody, Sally A. - Department of Anatomy and Cell Biology, George Washington University

 

Collection: Biology and Medicine

 
36 Efficient dendritic cell priming of T lymphocytes depends on the extracellular matrix protein mindin
 

Summary:  Molecular Biology Organization4102 #12;transgenic mice (Kuhn et al, 1995) and induced b1 integrin deletion... al, 2000) and OTII TCR transgenic mice (Barnden et al, 1998). To generate b1 integrin- deficient DC... integrin had reduced adhesion to mindin matrix, decreased expression of ...

  

Source: Rockey, Don - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
37 Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial migration and integrin-dependent cell adhesion
 

Summary:  Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin... of 1 integrins. These results suggest that cellubrevin-dependent membrane trafficking participates... ), and R. Jahn (MPI, Gottingen, FRG) respectively. The mouse monoclonal antibody anti-1 integrin (Cl18

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
38 Semaphorin 7A promotes axon outgrowth through integrins
 

Summary:  Semaphorin 7A promotes axon outgrowth through integrins and MAPKs R. Jeroen Pasterkamp*, Jacques J... formation during embryonic development. Unexpectedly, Sema7A enhancement of axon outgrowth requires integrin... function for semaphorins, identify an unexpected role for integrins and integrin-dependent ...

  

Source: Blackshaw, Seth - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
39 VIROLOGY 235, 293301 (1997) ARTICLE NO. VY978692
 

Summary:  with cDNAs of human VLA-2. After EV-1 infection, L cell transformants of human VLA-2 (a2b1 L cells... ) develop cytopathic effect (CPE) as expected, while 3T3 cell transformants of human VLA-2 (a2b1 3T3 cells... ...

  

Source: Racaniello, Vincent - Department of Microbiology, Columbia University

 

Collection: Biology and Medicine

 
40 How molecular imaging is speeding up antiangiogenic drug development
 

Summary:  - thelial growth factor receptor, integrin AvB3, matrix metalloproteinase, endoglin (CD105), and E... , integrins, and matrix metalloprotei- nases (MMP; ref. 8). Here, we will focus on three of the most... ) and VEGF receptors (VEGFR), integrin avh3, and MMPs (Fig. 2). During tumor angiogenesis, these molecules

  

Source: Rao, Jianghong - Department of Radiology, Stanford University

 

Collection: Biology and Medicine


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41 Focal adhesion regulation of cell behavior Michele A. Wozniak, Katarzyna Modzelewska, Lina Kwong, Patricia J. Keely*
 

Summary:  2004 Abstract Focal adhesions lie at the convergence of integrin adhesion, signaling and the actin... environment. We consider here how cells use focal adhesions to regulate signaling complexes and integrin... rights reserved. Keywords: Focal adhesion; Focal adhesion kinase; Integrin; Src; 3D matrix; Cell

  

Source: Keely, Patricia J. - Molecular and Cellular Pharmacology Training Program & Department of Pharmacology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
42 -Actinin-4 Is Required for Normal Podocyte Adhesion*S Received for publication,May 25, 2006, and in revised form, October 24, 2006 Published, JBC Papers in Press,November 2, 2006, DOI 10.1074/jbc.M605024200
 

Summary:  the strength of the integrin receptor-mediated linkagestothecytoskeletonbyapplyingforcetomicrobeadsbound... to an applied force than those bound to wild-type cells. Consistent with integrin-dependent -actinin-4-mediated... adhe- sion, phosphorylation of 1-integrins on -actinin-4-deficient podocytes is reduced. We rescued

  

Source: Ingber, Donald E. - Vascular Biology Program, Harvard University

 

Collection: Biology and Medicine

 
43 Lasp anchors the Drosophila male stem cell niche and mediates spermatid individualization
 

Summary:  individualization. Hub cell mislocalization can by phenocopied by expressing Lasp or bPS integrin RNAi transgenes... analyzed a mys (encoding bPS integrin) RNAi UAS transgene, which we ex- pressed in hub cells... : Received 25 June 2008 Accepted 30 June 2008 Available online 6 July 2008 Keywords: Lasp ...

  

Source: Schoeck, Frieder - Department of Biology, McGill University

 

Collection: Biology and Medicine

 
44 Lucas et al. Comparative transductions of breast cancer cells by three DNA viruses
 

Summary:  (CAR) or v integrin levels. In conclusion, our data suggest that human adenoviruses are excellent... on CAR or v integrin levels. Key words: breast, cancer, adenovirus, adeno-associated virus inserm... used vectors for cancer gene therapy (4). They lead to a transient, robust, transgene expression

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
45 Melanoma cell migration to type IV collagen requires activation of NF-jB Louis Hodgson1
 

Summary:  the endothelium, induced chemotaxis of a number of human melanoma cell lines in vitro by engaging a2b1 integrin... -mediated chemotaxis has been shown to involve a2b1 integrins (Hodgson ...

  

Source: Dong, Cheng - Department of Bioengineering, Pennsylvania State University

 

Collection: Engineering ; Biology and Medicine

 
46 Regulation of integrin affinity on cell surfaces Thomas Schu rpf and Timothy A Springer*
 

Summary:  Regulation of integrin affinity on cell surfaces Thomas Schu¨ rpf and Timothy A Springer... ; integrin aLb2) for intercellular adhesion molecules (ICAMs) on endothe- lia or antigen-presenting cells... . Our results lend support to the traction or translational motion dependence of integrin activation

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
47 RGD-based strategies for selective delivery of therapeutics and imaging
 

Summary:  for the visualization of v3- integrin, which demonstrates the feasibility of this approach. This review will summarize... in the integrin family. Integrins and RGD-based ligands for integrins are currently an intensely investigated... [7-10]. These pathogens gain entry into host cells by binding to specific ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
48 10.1101/gad1367806Access the most recent version at doi: 2006 20: 147-152Genes Dev.
 

Summary:  in transgenic mice expressing a dominant-negative form of WT1 in Sertoli cells, demonstrating the validity... and Cullen 2004). Using this approach, we generated transgenic mice with reduced WT1 levels in Sertoli cells... siRNA (Davies et al. 2004). The two exons in our siRNA-WT1 transgene lack ATG codons; therefore

  

Source: Wilkinson, Miles F. - Department of Reproductive Medicine, University of California at San Diego

 

Collection: Biology and Medicine

 
49 Effect of substrate mechanics on chondrocyte adhesion to modified alginate surfaces
 

Summary:  adhesion. High calcium ion concentrations have been shown (at 5.5 mM) to inhibit a2b1 adhesion [42... attachment to unmodified alginate and was significantly inhibited by antibodies to integrin subunits a3 and b... with actin stress fibers on stiffer substrates. The dependence of ...

  

Source: Bonassar, Larry - Sibley School of Mechanical and Aerospace Engineering, Cornell University

 

Collection: Engineering

 
50 II-Spectrin Is Critical for Cell Adhesion and Cell Cycle* Received for publication,February 19, 2008, and in revised form, October 2, 2008 Published, JBC Papers in Press,October 31, 2008, DOI 10.1074/jbc.M801324200
 

Summary:  , and modified expression of some integrins. Our results provide novel insights into spectrin functions... INSERMonJanuary26,2009www.jbc.orgDownloadedfrom tel-00377569,version1-22Apr2009 #12;protein (Rb), integrins ( 4, 5... against 3, 1, 3, and V 3 integrins were pur- chased from Chemicon International. Rabbit polyclonal anti

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
51 CD11c+ as an inflammatory biomarker and therapeutic target for atherogenesis
 

Summary:  (VLA-4, 41 integrin), intercellular adhesion molecule 1 (ICAM-1), and vascular cell adhesion molecule 1... ,95, X2, or complement receptor 4, is a member of the leukocyte CD11/CD18 (2) integrins, which also... are not clear. CD11/CD18 integrins have been shown to be involved in atherogenesis as evidenced by a significant

  

Source: Nguyen, Danh - Department of Public Health Sciences, University of California, Davis

 

Collection: Biology and Medicine ; Mathematics

 
52 Insulin Resistance in Striated Muscle-specific Integrin Receptor 1-deficient Mice*
 

Summary:  introduced flanking exon 2 of the entire mouse 1 integrin gene (40, 41) with transgenic mice carrying the MCK... Insulin Resistance in Striated Muscle-specific Integrin Receptor 1-deficient Mice* Received... of Medicine, The University of Iowa, Iowa City, Iowa 52242 Integrin receptor plays key roles in ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
53 Direct Cell Adhesion to the Angiopoietins Mediated by Integrins* Received for publication, January 11, 2001, and in revised form, April 26, 2001
 

Summary:  Direct Cell Adhesion to the Angiopoietins Mediated by Integrins* Received for publication, January... was independent of Tie2 and not limited to endothelial cells. Interestingly, when integrin-blocking agents were... hamster ovary-B2 cells lack- ing the 5 integrin subunit did not adhere to Ang-1, but they did adhere

  

Source: Mrksich, Milan - Department of Chemistry, University of Chicago

 

Collection: Chemistry

 
54 Human MutationREVIEW Mapping Structural Landmarks, Ligand Binding Sites, and
 

Summary:  . The collagen IV integrin receptors belong to the b1 subgroup, namely, a1b1 and a2b1 [Leitinger and Hohenester... inaccessible to cells in the native molecule [Herbst et al., 1988; Kim et al., 1994]. Integrins ...

  

Source: Jensen, Shane T. - Department of Statistics, University of Pennsylvania

 

Collection: Mathematics

 
55 Eur J Cell Biol. Author manuscript Podosome-type adhesions and focal adhesions, so alike yet so different
 

Summary:  the continuous, coordinated assembly and disassembly of integrin-mediated adhesions. An understanding of how... integrins regulate cell migration and invasiveness through the dynamic regulation of adhesions... (podosome type adhesions). These adhesion sites contain integrin clusters able to develop specialized

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
56 MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/01/$04.00 0 DOI: 10.1128/MCB.21.6.22032212.2001
 

Summary:  from experiments with transgenic mice bearing polyomavirus middle T antigen under the control... transgenic mice expressing a mutant middle T antigen decoupled from the phosphatidylinositol 3 -OH kinase... assess the role of Akt in mammary epithelial development and tumorigenesis, we generated transgenic mice

  

Source: Woodgett, Jim - Ontario Cancer Institute, University of Toronto

 

Collection: Biology and Medicine

 
57 2001 Macmillan Magazines Ltd Cell interactions with the extracellular matrix (ECM)
 

Summary:  of these adhesions, nevertheless, share two com- mon features -- they are mediated by INTEGRINS, and they interact... Pankov and Kenneth M. Yamada Integrin-mediated cell adhesions provide dynamic, bidirectional links... extracellular-matrix assembly, cell proliferation, differentiation, and death. This review describes integrin

  

Source: Geiger, Benjamin - Department of Molecular Cell Biology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
58 MINI REVIEW TUMOR REVERSION: CORRECTION OF MALIGNANT BEHAVIOR BY
 

Summary:  -Abl kinase activity.73 Data from transgenic mouse models provide evidence for the importance of the integrin... . Recent work in transgenic models and specialized cell culture systems has begun to define the spe- cific... by human mammary epithelial cells in 3D cultures. Antibody-medi- ated inhibition of ...

  

Source: Kenny, Paraic - Department of Developmental and Molecular Biology , Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
59 UNIVERSIT D'ORLANS COLE DOCTORALE ou SCIENCES ET TECHNOLOGIES
 

Summary:  .5 Transgenic mice YAC67 and YAC84............................................................. 1.6 Endothelial... .6.3.1 Cell Adhesion Molecules (CAMs).................................................... 1.6.3.2 Integrins... ................................................................................................................. 3.3 ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
60 MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/01/$04.00 0 DOI: 10.1128/MCB.21.15.51225131.2001
 

Summary:  on 1-Integrin To Promote Normal Liver Development MICHAEL WEINSTEIN,1,2 SATDARSHAN P. S. MONGA,3 YE... in the level of the 1-integrin and abnormal processing and localization of E-cadherin. Culture of mutant livers... at the 1-integrin, the level of which was increased by HGF in the cultured mutant livers. HGF treatment

  

Source: Weinstein, Michael - Department of Molecular Genetics, Ohio State University

 

Collection: Biology and Medicine


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61 JOURNAL OF VIROLOGY, 0022-538X/00/$04.00 0
 

Summary:  that internalization of heparan sulfate proteo- glycan-bound AAV-2 requires V 5 integrin and activation of the small... results indicate that V 5 integrin- mediated endocytosis of AAV-2 occurs through a Rac1 and PI3 kinase... integrins (55). Integrins are molecules involved in cell adhesion and motility (9, ...

  

Source: Engelhardt, John F. - Department of Anatomy and Cell Biology, University of Iowa

 

Collection: Biology and Medicine

 
62 Molecular Cell Short Article
 

Summary:  by cocrystal structures of I domains with physiological ligands, including the I domain of integrin a2b1... -Affinity aL Integrin I Domain Variant Bound to ICAM-5 Hongmin Zhang,1,2 Jose M. Casasnovas,5 Moonsoo Jin,6... @red.dfci.harvard.edu DOI ...

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
63 This Review is part of a thematic series on Integrins, which includes the following articles: Integrins and the Myocardium
 

Summary:  This Review is part of a thematic series on Integrins, which includes the following articles... : Integrins and the Myocardium Functional Consequences of Integrin Gene Mutations in Mice Integrins... in Vascular Development Integrin and Growth Factor Receptor Crosstalk Mechanical Signaling ...

  

Source: Ingber, Donald E. - Vascular Biology Program, Harvard University

 

Collection: Biology and Medicine

 
64 At 41 kJ/mol, the lowest incident kinetic energy investigated so far, we find that CD2H2
 

Summary:  of the Atnos1 mutant and complementation with a 35S-AtNOS1 transgene. (A) Wild-type (Col-0) and (B) Atnos1... -AtNOS1 transgene (rescued Atnos1) has green true leaves. (D) Atnos1 mutation inhibits shoot growth, as ob... 2003 Talin Binding to Integrin Tails: A Final Common Step in Integrin Activation Seiji ...

  

Source: Crawford, Nigel M. - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
65 MOLECULAR AND CELLULAR BIOLOGY, July 2010, p. 34803492 Vol. 30, No. 14 0270-7306/10/$12.00 doi:10.1128/MCB.00057-10
 

Summary:  /MAPK, and the upregulation of Sox9. Furthermore, disrupting fibronectin binding to integrin by the addition of RGD peptides... or by the knockdown of 5 integrin prevents the Pref-1 inhibition of adipocyte differentiation. Pref-1 activates... the integrin downstream signaling molecules, FAK and Rac, and ERK activation by Pref-1 ...

  

Source: Toledo, University of - Center for Diabetes and Endocrine Research (CeDER)

 

Collection: Biology and Medicine

 
66 1999 Macmillan Magazines Ltd NATURE CELL BIOLOGY | VOL 1 | SEPTEMBER 1999 | cellbio.nature.com E131
 

Summary:  (ECM) molecules, cell-surface growth-factor receptors, integrins, signal-transducing molecules... transformation5 , and studies of transgenic mice show that deregulated ECM remodelling can induce tumour... molecules and their cell-surface integrin receptors in anchorage-dependent growth control. Adhesion

  

Source: Ingber, Donald E. - Vascular Biology Program, Harvard University

 

Collection: Biology and Medicine

 
67 RESEARCH Open Access Adenoviruses with an avb integrin targeting
 

Summary:  RESEARCH Open Access Adenoviruses with an avb integrin targeting moiety in the fiber shaft... needs to be improved. Methods: Here, the utility of avb integrin targeting moiety Arg-Gly-Asp (RGD... the biodistribution of the virus [21]. Cell surface integrins are also impor- tant players in the adenovirus serotype

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
68 Dpt.de physiologie cellulaire et mtabolisme -Centre Mdical Universitaire -Genve Laboratoire d'optique biomdicale, EPFL
 

Summary:  .lasser@epfl.ch) Dynamic and high-resolution fluorescence imaging to dissect the integrin-dependent cytoskeleton... -matrix linkage in muscle fibers The goal of our research is to understand the mechanisms of integrin... the association of integrin receptors with its different adapter proteins, which are employed to regulate

  

Source: Radenovic, Aleksandra - Laboratory of Nanoscale Biology, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Physics

 
69 Characterization of Integrins and Associated Proteins Using MALDI Tandem Mass Spectrometry
 

Summary:  Characterization of Integrins and Associated Proteins Using MALDI Tandem Mass Spectrometry Igor... and Immunology, University of Manitoba, Winnipeg, Manitoba, Canada Integrins are heterodimeric adhesion molecules... arthritis, and tumor metastases. We are developing methods of studying integrins using MALDI MS and MS

  

Source: Ens, Werner - Department of Physics and Astronomy, University of Manitoba

 

Collection: Physics

 
70 Specificities of integrin signaling in the control of cell adhesion and adhesive strength Myriam Rgent1,2,3
 

Summary:  1 Specificities of integrin signaling in the control of cell adhesion and adhesive strength Myriam... .albiges-rizo@ujf-grenoble.fr Tel: 33 476 54 95 50 Fax: 33 476 54 94 25 Keywords: 51 integrin, integrin activation, adhesion... by integrin activation switch and their ability to modulate their clustering and ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
71 Structure 14, 16111616, November 2006 2006 Elsevier Ltd All rights reserved DOI 10.1016/j.str.2006.10.001 MinireviewComplement and the Multifaceted
 

Summary:  .C. (2000). Structural basis of collagen recognition by integrin a2b1. Cell 101, 47­56. Fredslund, F... .str.2006.10.001 MinireviewComplement and the Multifaceted Functions of VWA and Integrin I Domains Timothy A... for other VWA domains, including the I domains in ...

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
72 Mechanobiology and diseases of mechanotransduction
 

Summary:  ,transduction, including extracellular matrix molecules, transmembrane integrin receptors, cytoskeletal... structurestransmembrane integrin receptors, cytoskeletal structures and associated signal transduction components, may... : cytoskeleton; disease; extracellular matrix; integrin; mechanical forces; mechanotransduction; stress

  

Source: Ingber, Donald E. - Vascular Biology Program, Harvard University

 

Collection: Biology and Medicine

 
73 Introduction Fibronectin (FN), an extracellular glycoprotein, is secreted as
 

Summary:  of living cells, in a process that requires integrins and probably other cell surface receptors (Mosher... that integrins and associated molecules bridge the gap between the extracellular FN matrix and the intracellular... of a yeast GAL4 transgene) (Bloor and Kiehart, 2001). The FN-yfp and cfp-Moe expression vectors (10:1 ratio

  

Source: Erickson, Harold P. - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
74 Cell, Vol. 107, 195207, October 19, 2001, Copyright 2001 by Cell Press Regulating Axon Branch Stability
 

Summary:  integrins. Genetics 132, 519­528.transgenic insertion line, we did observe variations from experiment... ., 1990) and in vivo (Brouns et al., 2001). Upon growth factor stimulation or integrin activation, p190... transgenic dou- ity in maturing neurons. Rho family of small GTPases ble-stranded RNA ...

  

Source: Luo, Liqun - Department of Biology, Stanford University

 

Collection: Biology and Medicine

 
75 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  's personal copy Focal adhesion kinase and 1 integrin regulation of Na+ , K+ , 2Cl- cotransporter... rich chloride cells Na+, K+, 2Cl- cotransporter 1 integrin Focal adhesion kinase (FAK), also known... as PYK2, is a tyrosine kinase that functions in integrin-mediated signaling in mechanosensitive cells

  

Source: Marshall, William S. - Department of Biology, St. Francis Xavier University

 

Collection: Environmental Sciences and Ecology

 
76 Genomic organization and sequence variation of the human integrin subunit a8 gene (ITGA8)
 

Summary:  Genomic organization and sequence variation of the human integrin subunit a8 gene (ITGA8) Catherine... in revised form 31 July 2004; accepted 9 August 2004 Abstract The integrin a8 is highly expressed during... B.V./International Society of Matrix Biology. All rights reserved. Keywords: Integrin alpha chain

  

Source: Samudrala, Ram - Department of Microbiology, University of Washington at Seattle

 

Collection: Biotechnology ; Biology and Medicine

 
77 324 NATURE MEDICINE VOLUME 7 NUMBER 3 MARCH 2001 Fibronectins (Fns) are dimeric glycoproteins that exist in blood
 

Summary:  that fibronectins modulate cell proliferation, mi- gration and survival3­5 . Integrins serve as fibronectin... was highly efficient in liver using the Mx-Cre trans- gene compared with the Alb-Cre transgene (data... not shown), most experiments were performed with mice expressing the Mx-Cre transgene. As the western

  

Source: Erickson, Harold P. - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
78 Sarcomere Formation Occurs by the Assembly of Multiple Latent Protein Complexes
 

Summary:  the sarcomere but not in its initial formation. Finally, integrins appear essential for the interdigitation... the role of integrin adhesion complex in sarcomere assembly as starting sites of actin/thin filaments... that integrin signaling pathway components are required for sarcomere assembly [11­15]. Although not necessarily

  

Source: Higgins, Darren - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
79 DOI: 10.1126/science.276.5317.1425 , 1425 (1997);276Science
 

Summary:  the transgene fragment as the probe. 8. R. Vassar, M. Rosenberg, S. Ross, A. Tyner, E. Fuchs, Proc. Natl. Acad... ). 25. For electron microscopy, tissue pieces from two transgenic skin biopsies were fixed... synthesis, small (3 mm by 3 mm) skin biopsies from four transgenic and four control mice were incubated

  

Source: Mrksich, Milan - Department of Chemistry, University of Chicago

 

Collection: Chemistry

 
80 ture in vivo. So far, there is no evidence that tumors can stimulate the growth of
 

Summary:  the transgene fragment as the probe. 8. R. Vassar, M. Rosenberg, S. Ross, A. Tyner, E. Fuchs, Proc. Natl. Acad... ). 25. For electron microscopy, tissue pieces from two transgenic skin biopsies were fixed... synthesis, small (3 mm by 3 mm) skin biopsies from four transgenic and four control mice were incubated

  

Source: Chen, Christopher S. - Department of Bioengineering, University of Pennsylvania; Ingber, Donald E. - Vascular Biology Program, Harvard University; Prentiss, Mara - Department of Physics, Harvard University

 

Collection: Biology and Medicine ; Physics


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81 pathway is currently being delineated through the use of gain-of-function and
 

Summary:  ). Analyses of mutants and transgenic tissues and plants support the impor- tance of this central signaling... in transgenic plants (8, 24). Thus, phosphorylation of ARR1 and ARR2 likely eliminates negative regulation (Fig... . 1). Ectopic expression in transgenic Arabi- dopsis of ARR2, one of the rate-limiting tran- scription

  

Source: Sheen, Jen - Department of Genetics, Harvard University

 

Collection: Biotechnology ; Biology and Medicine

 
82 COCEBI-387; NO OF PAGES 8 Integrin structures and conformational signaling
 

Summary:  COCEBI-387; NO OF PAGES 8 Integrin structures and conformational signaling Bing-Hao Luo and Timothy... A Springer Integrins are cell adhesion molecules that play critical roles in development, wound healing... for integrin regulation and signaling, especially on how global conformational changes between bent

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
83 Unraveling ICAP-1 function : toward a new direction ? Bouvard Daniel*, Millon-Fremillon Anglique, Dupe-Manet Sandra, Block Marc R., Albiges-
 

Summary:  and pathological situations. Integrins are a large family of cell adhesion receptors composed of two non... and signalling. The short cytoplasmic domain of integrin can interact with cytoplasmic proteins that are either... shared by several different integrins or specific for one type of integrin. ICAP-1 ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
84 Molecular Biology of the Cell Vol. 14, 25702582, June 2003
 

Summary:  of the L/ 2 Integrin in Rap1-induced Adhesion and MigrationV Yumi Tohyama,* Koko Katagiri,* Ruggero Pardi... defined the cytoplasmic region of the L and 2 integrin that are required for Rap1-stimulated adhesion... in the response to the inside-out signaling and the subsequent dead- hesion process. INTRODUCTION The integrin

  

Source: Springer, Timothy A. - Immune Disease Institute & Department of Pathology, Harvard University

 

Collection: Biology and Medicine

 
85 Research Article 3683 Introduction
 

Summary:  of receptors that include the 1 and 4 integrins, discoidin domain receptors, syndecans, sulfated glycolipids... within an epithelial cell lineage of adult transgenic mice. Importantly, these results reveal a selective... -loxP recombination, crossing the floxed-DG transgenic mouse line (Cohn et al., 2002; Moore et al., 2002) with ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
86 ORIGINAL ARTICLE Extracellular matrix molecules regulate endothelial cell
 

Summary:  that mediates adhesion through a2b1and a1b1 [18]. Degradation of collagens by collagenases and gelatinases... inhibited by the combination of obtustatin and VP12, a1b1 and a2b1 antagonists [40], respect- ively (data... not ...

  

Source: Mosher, Deane F. - Molecular and Cellular Pharmacology Training Program & Department of Biomolecular Chemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
87 Introduction Adhesion complexes play key roles in many events, including
 

Summary:  integrin attachment sites. Surprisingly, transgenically expressed kinase-dead PAT-4 can rescue pat-4-null... proteins that are important for cell adhesion in C. elegans, including integrins (Williams and Waterston... : epithelial apical junctions, which have traits of adherens and tight junctions; integrin- ...

  

Source: Hardin, Jeff - Department of Zoology, University of Wisconsin at Madison

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
88 4047Research Article Introduction
 

Summary:  are the cooperative relationships among these receptors. Thus far, the integrins have been implicated (Muschler et al... ://jcs.biologists.org/cgi/content/full/119/19/4047/DC1 Key words: Dystroglycan, Laminin, Polarity, Mammary, Epithelial, Integrin Summary... and laminin-211 polymerized while interacting with DG and integrins on ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
89 product was rst quantied on an initial gel. The proportion of maternal or paternal alleles in each lane was then determined from a second gel after cutting the PCR product. These
 

Summary:  . C. Crystal structure of the I domain from Integrin a2b1. J. Biol. Chem. 272, 28512±28517 (1997). 31... kappa transgenes: Association of mutability with demethylation. Immunol. Cell. Biol. 79, 18±22 (2001... ±336 (1991). 29. Spanopoulou, E. et al. Functional ...

  

Source: Sejnowski, Terrence J. - Computational Neurobiology Lab, Salk Institute for Biological Studies

 

Collection: Biology and Medicine

 
90 Cortical deficiency of laminin 1 impairs the AKT/GSK-3 signaling pathway and leads to defects in neurite outgrowth and neuronal migration
 

Summary:  , indicating defects in integrin signaling pathways. Moreover, both phosphorylation and protein levels of GSK-3... that laminin regulates neurite growth and neuronal migration via integrin signaling through the AKT/GSK-3... 1 perturbs neuronal migration and impairs integrin and AKT/GSK-3 signaling, but cell proliferation

  

Source: Strickland, Sidney - Laboratory of Neurobiology and Genetics, Rockefeller University

 

Collection: Biology and Medicine

 
91 Involvement of Transmembrane Domain Interactions in Signal Transduction by / Integrins*
 

Summary:  Involvement of Transmembrane Domain Interactions in Signal Transduction by / Integrins* Received... of / heterodimeric integrins function together to bind ligands in the extracellular region and transduce signals... across cellular mem- branes. A possible function for the transmembrane re- gions in integrin signaling

  

Source: Engelman, Donald M.- Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
92 [CANCER RESEARCH 63, 847853, February 15, 2003] Modulation of Coxsackie-Adenovirus Receptor Expression for Increased Adenoviral
 

Summary:  Expression for Increased Adenoviral Transgene Expression1 Akseli Hemminki,2 Anna Kanerva, Bin Liu, Minghui... , prostate, and breast cancer. In this study we investigated the feasibility of increasing transgene ex... - pression by incubating ovarian cancer cells with various agents and then performing transgene expression

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
93 of CMG2 (PDB ID code 1SHT)11 was manually placed in the electron density. Model
 

Summary:  recognition by integrin a2b1. Cell 101, 47­56 (2000). 6. Petosa, C., Collier, R. J., Klimpel, K. R., Leppla, S... in vivo is likely to be Mg2þ , we have previously shown for integrin I domains that the stereochemistry... are 2.1 ^ 0.2 A° , identical to those ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
94 The development of peptide-based interfacial biomaterials for generating biological functionality on the surface of bioinert materials
 

Summary:  ­cell interactions, but still adheres cells through interactions with integrins from the b1 family (e.g., a2b1) [65... attachment with insufficient integrin interactions, which in some cases can adversely impact down- stream... to the ...

  

Source: Boston University, Center for Nanoscience and Nanobiotechnology

 

Collection: Materials Science

 
95 BioMed Central Page 1 of 11
 

Summary:  and Signaling Open AccessResearch Regulation of trophoblast beta1-integrin expression by contact... increased expression of 1 integrin. Since trophoblast migration within the uterine vasculature involves... -cell contact and/or factors released by endothelial cells could regulate trophoblast integrin expression

  

Source: Barakat, Abdul - Department of Mechanical and Aeronautical Engineering, University of California, Davis

 

Collection: Biology and Medicine

 
96 Title: Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy
 

Summary:  Title: Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy... function was examined in vitro in arteries from transgenic mice that express a mutant Notch3 in vSMC. Tail... artery segments from transgenic and normal wild-type male mice were mounted on small-vessel arteriographs

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
97 Nature Macmillan Publishers Ltd 1998 letters to nature
 

Summary:  mutantphenotypeofpersistingcellcorpsesingermlinetransformation Table 1 Expression of DOCK180 rescues the DTC-migration defect in ced-5 mutants hsp transgene* ced... ; -, no rescue. Numbers in parentheses indicate the number of rescued lines and the total number of transgenic... protein CRK6 , which consists mainly of SH2 and SH3 domains16 and has ...

  

Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
98 The Differential Effect of Endothelial Cell Factors on In Vitro Motility of Malignant and Non-malignant Cells
 

Summary:  indicates that the ligands for the a2b1 integrin are collagen and laminin, the ligands for FIGURE 6. Effect... molecules used by the Calu-1 cells to upregulate motility in response to HUVEC factors. Of these, the ...

  

Source: Zhu, Cheng - Department of Biomedical Engineering, Georgia Institute of Technology and Emory University

 

Collection: Engineering ; Biology and Medicine

 
99 THE OCULAR SURFACE / JANUARY 2005, VOL. 3, NO. 1 / www.theocularsurface.com 15 Accepted for publication November 2004
 

Summary:  , niche, transient amplifying cell, 9 integrin, -enolase, microenvironment I. INTRODUCTION: WHAT IS A STEM... components--cyclins D and E,37 and p10738; and 5) others--9 integrin,39 melanin,40 p63,41 and ATP-bind- ing... of -enolase and 9-integrin in the adult rat limbus. The distribution of these two proteins is partially

  

Source: Moody, Sally A. - Department of Anatomy and Cell Biology, George Washington University

 

Collection: Biology and Medicine

 
100 Integrins in Slow-Cycling Corneal Epithelial Cells at the Limbus in the Mouse
 

Summary:  Integrins in Slow-Cycling Corneal Epithelial Cells at the Limbus in the Mouse AHDEAH PAJOOHESH... Medical Center, Washington, DC, USA Key Words. Adhesion receptors · Integrins · Mouse ABSTRACT Adult... in the central cornea, 1-, 4-, 3-, and 6-integrins are more highly expressed overall in central corneal basal

  

Source: Moody, Sally A. - Department of Anatomy and Cell Biology, George Washington University

 

Collection: Biology and Medicine


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