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Sample search results for: a-globin locus chromatin

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1 Histone modification analysis by chromatin immunoprecipitation from a low number of cells on a microfluidic platform
 

Summary:  the microfluidic ChIP while testing bA -globin gene as a negative control. Results and discussion In this work, we... genomic locations (FR and bA -globin genes) for enrichment of acetylated histone H3. Previous studies have... shown that in 6C2 cells the FR promoter is acetylated at histone H3 and the ...

  

Source: Lu, Chang - Department of Chemical Engineering, Virginia Tech

 

Collection: Engineering ; Biology and Medicine

 
2 Globin Genes: Evolution Ross C Hardison, Pennsylvania State University, University Park, Pennsylvania, USA
 

Summary:  al. (1990) A major positive regulatory region located far upstream of the human a-globin gene locus... composed of two a-globin and two b-globin polypeptides with their associated heme groups. This multisubunit... related to a-globin and two subunits from the family of proteins related to b globin (Figure ...

  

Source: Hardison, Ross C. - Department of Biochemistry and Molecular Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
3 A comparative genomics approach
 

Summary:  Avian -globin Mammalian -globin Mammalian A-globin Avian A-globin Amphibian A-globin D-globin B Fish... -globin Amphibian L-globin Mammalian -globin Avian -globin Mammalian -globin Mammalian A-globin Avian A-globin... Amphibian A-globin D-globin A Mammalian ...

  

Source: Ray, David - Department of Biochemistry and Molecular Biology, Mississippi State University

 

Collection: Environmental Sciences and Ecology

 
4 A R T I C L E S Variegated gene expression caused by cell-specific
 

Summary:  -globin LCR and a human A-globin­green fluorescent protein (GFP) reporter gene into the 8C3­C4 locus... LCR-AS 5 kb Rad23a P P P: Puromycin N: Neomycin G: GFP Rad23a 8C3­C4 A-globin­GFP-AS A-globin­GFP-S A-globin... .5 Embryonic blood 0 1.0 0.5 A-globin: AS ASAS S ...

  

Source: Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
5 The Molecular Basis of High-Altitude Adaptation in Deer Mice
 

Summary:  genetic analysis of a two-locus a-globin polymorphism that underlies physiological adaptation to high... for maintaining variation in protein function. Here we report a population genetic analysis of the two- locus a-globin... in the Coding Regions of the 59 and 39 a-Globin Paralogs ...

  

Source: Dean, Matthew D. - Department of Ecology and Evolutionary Biology, University of Arizona; Nachman, Michael - Department of Ecology and Evolutionary Biology, University of Arizona; Storz, Jay F. - School of Biological Sciences, University of Nebraska-Lincoln

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
6 JOURNAL OF CELLULAR PHYSIOLOGY 205:19 (2005) REVIEW ARTICLES
 

Summary:  -1 (HS1) and a-globin (HS-26) loci, an intronic enhancer of the ALAS-2 locus, and an intronic site... , revealed GATA-1 occupancy at b-globin, a-globin, ALAS-2, EKLF, GATA-2, Tac-2, FOG-1, and c-Myc loci... with chromatin is that GATA-1 and GATA- 2 often occupy the same chromosomal region of a ...

  

Source: Bresnick, Emery H. - Molecular and Cellular Pharmacology Training Program & Department of Pharmacology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
7 PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive
 

Summary:  modifications over the a-globin locus. (A, B) ChIP was performed on crosslinked chromatin from MEL cells... intervals over a 35 kb region at the a-globin locus. This locus contains two a-globin genes, a-1 (containing... ChIP with the GATA-1 ...

  

Source: Skoultchi, Arthur - Department of Cell Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
8 A Genomic Fossil Reveals Key Steps in Hemoglobin Loss by the Antarctic Icefishes
 

Summary:  species have lost the adult b-globin gene but retain a truncated a-globin pseudogene. Surprisingly... fixed in the clade: 1) the a- globin pseudogene of the majority of species and 2) the inactive ab... , retaining only a pseudogene that consists of a 3# fragment of the a-globin gene (Cocca et al. 1995; Zhao ...

  

Source: Near, Thomas J. - Department of Ecology and Evolutionary Biology, Yale University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
9 Cell, Vol. 111, 151154, October 18, 2002, Copyright 2002 by Cell Press MinireviewSetting the Boundaries
 

Summary:  the heterochromatic block present in the chicken -globin locus. Instead, severaldomains of silenced chromatin... locus suggests that, whereas the role of the insulator in chicken is to maintain an open chromatin... Setting the Boundaries of Chromatin Domains and Nuclear Organization ila ...

  

Source: Corces, Victor G. - Department of Biology, Emory University; Labrador, Mariano -Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee

 

Collection: Biology and Medicine

 
10 Rapid Rates of Lineage-Specific Gene Duplication and Deletion in the a-Globin Gene Family
 

Summary:  Rapid Rates of Lineage-Specific Gene Duplication and Deletion in the a-Globin Gene Family Federico... create the appearance of recent common ancestry. Here we report a comparative genomic analysis of the a-globin... ). According to this explanation, the ho- mogenization of sequence variation between paralogous a-globin genes

  

Source: Storz, Jay F. - School of Biological Sciences, University of Nebraska-Lincoln

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
11 Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific
 

Summary:  . We use the murine -globin locus to investigate how transcrip- tional control occurs within chromatin... of -globin RNA expression in the cell lines of A. -globin RNA levels were normalized to glyceraldehyde-3... in the locus, acetylated chromatin of the promoter ...

  

Source: Bresnick, Emery H. - Molecular and Cellular Pharmacology Training Program & Department of Pharmacology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
12 2006/07HIGHLIGHT HIGH-QUALITY RESEARCHER
 

Summary:  and compacted into chromosomes it is known as chromatin. Changes in the physical arrangement of chromatin appear... - mediated changes in chromatin structure govern gene expression. Often, these structural changes involve... the looping of chromatin, which can bring spatially distinct regions of DNA into ...

  

Source: Rambaut, Andrew - School of Biological Sciences, University of Edinburgh

 

Collection: Biology and Medicine

 
13 Recent results in living cells have now established the existence of levels of chromatin folding above the 30 nm fiber
 

Summary:  the locus open chromatin state. 37. Reik A, Telling A, Zitnik G, Cimbora D, Epner E, Groudine M... 307 Recent results in living cells have now established the existence of levels of chromatin... of this large-scale chromatin organization, including its possible role in regulating gene expression. Addresses

  

Source: Carpenter, Anne E. - Broad Institute Imaging Platform, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
14 Broadening of DNA replication origin usage during metazoan cell differentiation
 

Summary:  of the chicken beta-globin locus: early-firing origins at the 5' HS4 insulator and the rho- and betaA-globin... , respectively. The #12;14 horizontal double arrow over the A-globin gene indicates a 1.5 kb zone of initiation... , respectively. Figure 2: Nascent-strand maturation analysis around the - and ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
15 Copyright 0 1986 by the Genetics Society of America GENETIC ANALYSIS OF A MOUSE T COMPLEX LOCUS
 

Summary:  patterns (SDPs) of Rpl7, a-globin pseu- dogene 4 (Hbdps) and H-2 in the BXH RI strains (Table 3) suggested... of a genomic clone of a-globin pseudogene 4 (LEDERet al. 1981) to MspI-digested liver DNA revealed a number... alleles (Table 4). D'EUSTACHIOet al. (1984) also identified three TaqI alleles (a, b and c ) of the a-globin

  

Source: Silver, Lee - Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine ; Multidisciplinary Databases and Resources

 
16 DOI 10.1007/s00412-005-0015-7 MINI-REVIEW
 

Summary:  , Bickmore WA (2004) Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction... chromatin decondensation induced in a developmentally activated transgene locus. J Cell Sci 118... and deactivation related changes in the three-dimensional structure of chromatin ...

  

Source: Shaw, Peter - Cell and Developmental Biology Department, John Innes Centre

 

Collection: Biology and Medicine

 
17 Copyright 2008 by the Genetics Society of America DOI: 10.1534/genetics.107.080903
 

Summary:  Functional Divergence Among Triplicated a-Globin Genes in Rodents Jay F. Storz,*,1 Federico G. Hoffmann... of this study was to test whether amino acid differences among triplicated a-globin paralogs of the Norway rat... or modified physiological tasks. In each rodent species, the two paralogs at the 59-end of the a-globin gene

  

Source: Storz, Jay F. - School of Biological Sciences, University of Nebraska-Lincoln

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
18 Chromosomes and Chromatin Anne C Nye, University of Illinois, Urbana, Illinois, USA
 

Summary:  a repressive chromatin state surrounding the gene locus. Silencing of these genes is related to speci®c gene... Chromosomes and Chromatin Anne C Nye, University of Illinois, Urbana, Illinois, USA Ramji R... on their functional state? Chromatin Structure Local chromatin structure ± the ...

  

Source: Carpenter, Anne E. - Broad Institute Imaging Platform, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
19 Peter Meyer Lab home page Plant epigenetics and transgene silencing
 

Summary:  or inactive epigenetic state of a genetic locus is its packaging into an open and accessible or into a closed... and repressive chromatin structure. Epigenetic patterns can be passed on to the next generation but they can also... . Epigenetic changes alter chromatin conformation and affect a gene's potential to be transcribed. ...

  

Source: Meyer, Peter - Centre for Plant Sciences & Faculty of Biological Sciences, University of Leeds

 

Collection: Biology and Medicine

 
20 MOLECULAR AND CELLULAR BIOLOGY, Feb. 2005, p. 958968 Vol. 25, No. 3 0270-7306/05/$08.00 0 doi:10.1128/MCB.25.3.958968.2005
 

Summary:  -scale chromatin decondensation of an endogenous mammalian locus (7) and our previous work on the estrogen receptor... . Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes... Effects of Acidic Activators on Large-Scale Chromatin ...

  

Source: Carpenter, Anne E. - Broad Institute Imaging Platform, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine


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21 Vol. 11, No. 8MOLECULAR AND CELLULAR BIOLOGY, Aug. 1991, p. 4147-4156 0270-7306/91/084147-10$02.00/0
 

Summary:  -globin transgene expression (41), while two of these 5' super-HS sites could stimulate high levels of human a-globin... -level erythroid expression of human a-globin genes in transgenic mice. Proc. Natl. Acad. Sci. USA 86:37-41. 43... following cold exposure. To identify cis-regulatory elements, approximately 50 kb of chromatin ...

  

Source: Wagner, Diane - Institute of Arctic Biology, Department of Biology and Wildlife, University of Alaska Fairbanks

 

Collection: Environmental Sciences and Ecology

 
22 Four-dimensional imaging of chromatin dynamics during the assembly of the interphase nucleus
 

Summary:  large-scale chromatin folding and transcriptional activity. For instance, positioning of a locus near... Four-dimensional imaging of chromatin dynamics during the assembly of the interphase nucleus E. M... , chromatin, confocal microscopy, four-dimensional imaging, interphase nucleus, nuclear organization ...

  

Source: Liere, Robert van - Wiskunde en Informatica, Technische Universiteit Eindhoven

 

Collection: Computer Technologies and Information Sciences

 
23 Human centromeric chromatin is a dynamic chromosomal domain that can spread
 

Summary:  Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA... for review September 12, 2005) Human centromeres are specialized chromatin domains containing the centromeric... dimethy- lated at lysine 4, distinguishing centromeric chromatin (CEN chro- matin) from flanking

  

Source: Sullivan, Beth A. - Department of Genetics and Genomics, Boston University

 

Collection: Biology and Medicine

 
24 Discovery and Annotation of Functional Chromatin Signatures in the Human Genome
 

Summary:  Discovery and Annotation of Functional Chromatin Signatures in the Human Genome Gary Hon1,2 , Wei... elements encoded by the genome. Recent studies have shown that distinct chromatin signatures mark a variety... functions. To identify novel chromatin signatures in the human genome, we apply a de novo pattern

  

Source: Wang, Wei - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Chemistry ; Biology and Medicine

 
25 2006 Nature Publishing Group Chromatin organization and cell fate switch respond
 

Summary:  show that during this event the chromatin state around the GL2 locus is not inherited... Fig. 2a, b). This result shows that the chromatin state around the GL2 locus differs in the two types... -type-specific chromatin organization at the GL2 locus in meristematic ...

  

Source: Shaw, Peter - Cell and Developmental Biology Department, John Innes Centre

 

Collection: Biology and Medicine

 
26 http://genomebiology.com/2001/2/3/reviews/0002.1 Nuclear dynamics: where genes are and how they got there
 

Summary:  of a chromatin locus has strong consequences for its activity, and that prox- imity to heterochromatin directly... ? And how rapidly can a chromatin locus move, and what factors mediate the movement of loci? Chromatin... cognate transcription factor) provides a way of detecting a specific ...

  

Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee

 

Collection: Biology and Medicine

 
27 Developmental and species-divergent globin switching are driven by BCL11A
 

Summary:  of ontogeny16,17 . First, weexamined the relative expression of human c- and b-globin (with murine a-globin... and an overall reduction in the percentage of cells with a PT-FISH signal (using the murine a-globin control... , probes were made to target murine a-globin (ma), human b-globin (hb) and human c-globin (hc

  

Source: Voss, S. Randal - Department of Biology, University of Kentucky

 

Collection: Biology and Medicine

 
28 Research Article Analysis of Mcm27 chromatin binding during anaphase
 

Summary:  Research Article Analysis of Mcm2­7 chromatin binding during anaphase and in the transition... . It is likely that Mcm2­7 proteins are loaded onto chromatin simultaneously as a pre-formed hexamer although... yeast, we have compared the levels and chromatin binding of Mcm2­7 proteins during the fission yeast

  

Source: Kearsey, Stephen - Department of Zoology, University of Oxford

 

Collection: Biology and Medicine

 
29 ATP-dependent Chromatin Remodeling by the Saccharomyces cerevisiae Homologous Recombination
 

Summary:  by the HO endonuclease at the MAT locus located on chromosome 3 (27, 32). ChIP was Chromatin Remodeling... ATP-dependent Chromatin Remodeling by the Saccharomyces cerevisiae Homologous Recombination Factor... with the Rad51 recombinase in the D-loop reaction. By chromatin immunoprecipitation (ChIP), we show ...

  

Source: Roth, David B. - Langone Medical Center, New York University

 

Collection: Biology and Medicine

 
30 930 Research Paper Interphase chromosomes undergo constrained diffusional
 

Summary:  -particle tracking, we directly measured the motion of interphase chromatin, at high resolution and in three... dimensions. We found that chromatin does indeed undergo significant diffusive motion within the nucleus... , but this motion is constrained such that a given chromatin segment is free to move within only a limited ...

  

Source: Agard, David - Department of Biochemistry and Biophysics, University of California at San Francisco; Murray, Andrew W. - Department of Molecular and Cellular Biology, Harvard University; Straight, Aaron - Department of Biochemistry, Stanford University

 

Collection: Biology and Medicine ; Biotechnology

 
31 A R T I C L E S 1076 VOLUME 11 NUMBER 11 NOVEMBER 2004 NATURE STRUCTURAL & MOLECULAR BIOLOGY
 

Summary:  modifications are indicators of active or repressed chromatin, and the proposed `histone code' hypothesis... for chromatin regulation2. For example, acetylation of his- tones H3 and H4, and H3 methylation at Lys4, have... -Me) is typically associated with transcriptionally active chromatin, whereas methylation at Lys9 (H3

  

Source: Sullivan, Beth A. - Department of Genetics and Genomics, Boston University

 

Collection: Biology and Medicine

 
32 Chromosoma ( . ) : 110 DOI 10.1007/s00412-005-0001-0
 

Summary:  . Beth A. Sullivan Control of gene expression and assembly of chromosomal subdomains by chromatin... April 2005 # Springer-Verlag 2005 Abstract Epigenetic regulation of higher-order chromatin structure... - somal proteins that establish and maintain distinctive types of chromatin, such as euchromatin

  

Source: Sullivan, Beth A. - Department of Genetics and Genomics, Boston University

 

Collection: Biology and Medicine

 
33 Lineage-Specific Patterns of Functional Diversification in the a-and b-Globin Gene Families of Tetrapod Vertebrates
 

Summary:  diversification of the a-globin gene cluster in the stem lineage of tetrapods, the physiological division of labor... in the form of an orphaned b-like globin gene (x-globin) that is located at the 3# end of the a-globin gene... and postnatal life (Hardison 2001; Alev et al. 2008, 2009). In the a-globin gene family, the ...

  

Source: Storz, Jay F. - School of Biological Sciences, University of Nebraska-Lincoln

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
34 ChromaSig: A Probabilistic Approach to Finding Common Chromatin Signatures in the Human Genome
 

Summary:  enriched locus where we search for a chromatin signature motif of size 4-kb. This choice of search region... of possible probes in the locus. Finding Distinct Chromatin Signatures The enriched loci above are not grouped... by ChromaSig. Each horizontal line in the heatmap represents ...

  

Source: Wang, Wei - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Chemistry ; Biology and Medicine

 
35 Copyright 2001 by the Genetics Society of America The Gypsy Insulator of Drosophila Affects Chromatin
 

Summary:  Chromatin Structure in a Directional Manner Siquan Chen and Victor G. Corces Department of Biology... for publication September 28, 2001 ABSTRACT Chromatin insulators are thought to regulate gene expression... by establishing higher-order domains of chromatin organization, although the specific mechanisms by which

  

Source: Corces, Victor G. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
36 699RESEARCH ARTICLE INTRODUCTION
 

Summary:  H3S10 phosphorylation by the JIL-1 kinase is important for maintaining chromatin structure and gene... demonstrated that a reduction in JIL-1 kinase activity leads to a global disruption of chromatin structure... euchromatic chromatin regions. To test this hypothesis we applied a LacI-tethering system that has previously

  

Source: Johansen, Kristen M - Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University

 

Collection: Biology and Medicine

 
37 Introduction The minichromosome maintenance proteins (Mcm 2-7) have
 

Summary:  ). In particular, the association of Mcm proteins with chromatin appears to be the final step in the formation... the binding of Mcm proteins. Hence, the binding of Mcm 2-7 to chromatin likely represents functional licensing... ) dihydrofolate reductase (DHFR) locus can be achieved in Xenopus egg extracts using intact, ...

  

Source: Blow, J. Julian - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee

 

Collection: Biology and Medicine

 
38 Seminars in Cell & Developmental Biology 19 (2008) 580585 Contents lists available at ScienceDirect
 

Summary:  or even different parts of an individual locus. Epigenetic marks of silent chromatin are histone... Direct Seminars in Cell & Developmental Biology journal homepage: www.elsevier.com/locate/semcdb Review Chromatin... 2008 Keywords: Cell differentiation Epidermal cell Chromatin state Histones a b s t r a c ...

  

Source: Shaw, Peter - Cell and Developmental Biology Department, John Innes Centre

 

Collection: Biology and Medicine

 
39 Chromosome Segregation and Aneuploidy series Centromere formation: from
 

Summary:  for the mitotic kinetochore, the interaction site between the chromosome and the mitotic spindle. The chromatin... the formation and maintenance of centromeric chroma- tin and propose a chromatin self-assembly model... of the molecular features that distinguish centro- meres from other chromatin have been defined. Centro- meric ...

  

Source: Straight, Aaron - Department of Biochemistry, Stanford University

 

Collection: Biology and Medicine

 
40 INCYTES from MBCSeptember, Vol. 20, Nos. 17 and 18 Transportin Regulates Major Mitotic Assembly Events: From Spindle to Nuclear Pore
 

Summary:  the Seeding of Chromatin with Initiation Sites for Nuclear Pore Assembly Asaf Rotem, Rita Gruber, Hagai Shorer... regulate the earliest known step in NPC assembly, the seeding of chromatin with the critical proteins ELYS... , Gruber, Shorer et al. focus on the chromatin seeding step and its regulation by importin . Importin

  

Source: Forbes, Douglass - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine


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41 Epigenetic mechanisms are heritable traits that are mediated by changes in a genetic locus that do not involve a
 

Summary:  modifications to locus-specific patterns. The figure shows two hypothetical epigenetic states of open chromatin... 457 Epigenetic mechanisms are heritable traits that are mediated by changes in a genetic locus... that do not involve a modification at the nucleotide level. As eukaryotic DNA is organised in ...

  

Source: Meyer, Peter - Centre for Plant Sciences & Faculty of Biological Sciences, University of Leeds

 

Collection: Biology and Medicine

 
42 Characterization of a Widely Expressed Gene (LUC7-LIKE; LUC7L) Defining the Centromeric Boundary
 

Summary:  ., and Bernini, L. (1993). Homology of a 130-kb region enclosing the a-globin gene cluster, the a-locus control... gene containing the major human a-globin regulatory element. Genomics 29: 679­689, doi:10.1006/geno... that this gene marks the centromeric extent of the region of conserved synteny between the human -globin ...

  

Source: Hardison, Ross C. - Department of Biochemistry and Molecular Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
43 Boundary elements and nuclear organization Maya Capelson, Victor G. Corces *
 

Summary:  of eukaryotic genomes is thought to be necessary for the proper regulation of gene expression. Chromatin... , as they may be involved in creating independent chromatin domains. Recent advances in understanding... of chromatin and in organizing chromatin into structural compartments within the nucleus. ...

  

Source: Corces, Victor G. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
44 Introduction The higher order chromatin structure is an important regulatory
 

Summary:  Introduction The higher order chromatin structure is an important regulatory mechanism of gene... euchromatin and much denser chromatin regions referred to as heterochromatin (Heitz, 1928). Heterochromatin... is essential for the establishment of a transcriptionally competent state of chromatin (Kadonaga, 1998; Roh et

  

Source: Rippe, Karsten - BioQuant, Universität Heidelberg

 

Collection: Biology and Medicine

 
45 Histone H3K4 methylation keeps centromeres open for business
 

Summary:  of the genome. The centromere is an essential chromosomal locus required for chromosome segregation during cell... ). Chromatin containing CENP-A is periodically interrupted by nucleosomes containing H3K4me2, a modification... -methylated H3K9, H3K27 and H4K20. The functional significance of a chromatin landscape at centro- meres

  

Source: Sullivan, Beth A. - Department of Genetics and Genomics, Boston University

 

Collection: Biology and Medicine

 
46 Annu. Rev. Genet. 2001. 35:193208 Copyright c 2001 by Annual Reviews. All rights reserved
 

Summary:  -sensitive and acetylated chromatin of the -globin locus and the more condensed, DNase I-resistant and hypoacetylated... chromatin located outside of the locus (41). The insulator activity was originally mapped to a 250-bp DNA... element and condensed chromatin region separate the chicken ...

  

Source: Corces, Victor G. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
47 MINIREVIEW / MINISYNTHSE Molecular basis of transcriptional silencing in
 

Summary:  at the inactive HML locus (Terleth et al. 1989); these findings suggest that access to DNA in silenced chromatin... of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HML. Mol. Cell. Biol. 18: 5392... : telomeres (Gottschling et al. 1990), the rDNA locus ...

  

Source: Widom, Jon - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
48 Transcriptional Regulatory Elements in the Human
 

Summary:  of fetal hemoglobin 175 bp upstream of TSS (Oct-1, GATA-1) A-globin (62) Progressive myoclonus epilepsy... promoters, prox- imal promoters, distal enhancers, silencers, insulators/boundary el- ements, and locus... .annualreviews.org byStanfordUniversityRobertCrownLawLib.on04/03/07.Forpersonaluseonly. #12;LCR: locus control region

  

Source: Bejerano, Gill - Departments of Computer Science & Developmental Biology, Stanford University

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
49 Roles of Chromatin Remodeling Factors in the Formation and Maintenance of Heterochromatin Structure*S
 

Summary:  chromatin and heterochromatin, respec- tively. The HML locus including the E and I silencers is flanked... of sequences from the silent HML and HMR loci as well as active ACT1 locus in the immunoprecipitated chromatin... Roles of Chromatin Remodeling Factors in the Formation and ...

  

Source: Bi, Xin - Department of Biology, University of Rochester

 

Collection: Biology and Medicine

 
50 Nucelus 2:5, 410-424; September/October 2011; 2011 Landes Bioscience ReSeaRch papeR
 

Summary:  /20/11; Revised: 08/11/11; Accepted: 08/12/11 http://dx.doi.org/10.4161/nucl.2.5.17736 Introduction Chromatin... acts as the nuclear equivalent to the cytoskeleton to organize chromatin.6-8 In an alternative view... that are tightly interconnected with the gene expression state of a given locus.9 This dynamic genome scaffold

  

Source: Rippe, Karsten - BioQuant, Universität Heidelberg

 

Collection: Biology and Medicine

 
51 Chromatin regulation of plant development Doris Wagner
 

Summary:  of the superman locus. Plant Mol Biol 2001, 46:171-183. Chromatin regulation of plant development Wagner 27 www... Chromatin regulation of plant development Doris Wagner Chromatin remodeling factors are being... processes. Recent studies have begun to de®ne the many functions of ...

  

Source: Plotkin, Joshua B. - Department of Biology, University of Pennsylvania

 

Collection: Biology and Medicine

 
52 Molecular Biology of the Cell Vol. 14, 38763887, September 2003
 

Summary:  Functions after Pre- replicative Complex Formation To Promote Cdc45 Chromatin Binding Juraj Gregan,* Karola... : Douglas Koshland Using a cytological assay to monitor the successive chromatin association of replication... has no effect on Mcm2 chromatin association, and thus pre-replicative complex (pre-RC) formation

  

Source: Kearsey, Stephen - Department of Zoology, University of Oxford

 

Collection: Biology and Medicine

 
53 MOLECULAR AND CELLULAR BIOLOGY, June 2009, p. 29602981 Vol. 29, No. 11 0270-7306/09/$08.00 0 doi:10.1128/MCB.01054-08
 

Summary:  of the PHO84 ORF for chromosomal and plasmid locus, respectively). For secondary cleavage after chromatin... as described above for the chromosome locus. RESULTS The chromatin structure at the PHO84 promoter undergoes... change of the histone H3 occupancy at a telomere control locus. ...

  

Source: Yuan, Guo-Cheng "GC" - Dana-Farber Cancer Institute, Harvard University

 

Collection: Biology and Medicine

 
54 A positive but complex association between meiotic double-strand break hotspots and open chromatin
 

Summary:  evidence for a chromatin role comes from S. pombe. At the S. pombe ade6-M26 locus, MNase sensitivity... recombination are generally associated with open chromatin Evidence from locus-specific studies strongly... - dependent, nonredundant information about the chromatin profile at each ...

  

Source: Copenhaver, Gregory P. - Department of Biology, University of North Carolina at Chapel Hill

 

Collection: Biology and Medicine

 
55 Strategies to Insulate Lentiviral Vector-Expressed Ali Ramezani and Robert G. Hawley
 

Summary:  of a lentiviral vector, such as locus control regions (LCRs) and ubiquitously acting chromatin opening elements... of neighboring chromatin on single-copy transgene expression. The modifications include utilization of strong... the transcriptional unit with chromatin domain insulators. Protocols are provided ...

  

Source: Moody, Sally A. - Department of Anatomy and Cell Biology, George Washington University

 

Collection: Biology and Medicine

 
56 ISWI Regulates Higher-Order Chromatin Structure and Histone H1 Assembly In Vivo
 

Summary:  ISWI Regulates Higher-Order Chromatin Structure and Histone H1 Assembly In Vivo Davide F. V. Corona... -dependent chromatin-remodeling factors play key roles in transcription and other processes by altering the structure... -order chromatin structure, but its role in this process remains poorly understood. To clarify the role of ...

  

Source: Scott, Matthew - Departments of Developmental Biology, Genetics, & Bioengineering, Stanford University

 

Collection: Biotechnology ; Biology and Medicine

 
57 Acf1 confers unique activities to ACF/CHRAC and promotes the
 

Summary:  of chromatin in vivo Dmitry V. Fyodorov,1,3,6 Michael D. Blower,2,4,6 Gary H. Karpen,2,5 and James T. Kadonaga1... , California 92037, USA Chromatin assembly is required for the duplication of chromosomes. ACF (ATP... -utilizing chromatin assembly and remodeling factor) catalyzes the ATP-dependent assembly of periodic nucleosome ...

  

Source: Karpen, Gary - Department of Genome Biology, Lawrence Berkeley National Laboratory

 

Collection: Biotechnology ; Biology and Medicine

 
58 ligation of an as-yet-undescribed ligand,as well as the persistence of specific antigen, help to
 

Summary:  Ifng expressionIfng Charalampos G Spilianakis & Richard A Flavell Intensive characterization of the locus encoding... is an important mechanism that controls transcriptional activation or repression of the Ifng locus (encoding... interferon-Ifng locus (encoding interferon-Ifng (IFN- (IFN- )). In)). In this issue of Nature ...

  

Source: Spilianakis, Charalampos G. "Babis" - Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology, Hellas

 

Collection: Biology and Medicine

 
59 RESEARCH Open Access Modulated contact frequencies at gene-rich loci
 

Summary:  that the chromatin may undergo at that scale. Constraints resulting from locus-specific interactions are easily... reflect a preferential statistical shape that the chromatin tends to adopt when no strong locus... of strong locus-specific interactions, some gene-rich domains of the ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
60 COPLBI-471; NO OF PAGES 8 Histone modifications and dynamic regulation of genome
 

Summary:  -mediated locus accessibility and altered cell fate. 33. Caro E, Castellano MM, Gutierrez C: A chromatin link... in plants Jennifer Pfluger and Doris Wagner In all eukaryotes chromatin physically restricts... to exogenous cues. Among the multiple epigenetic mechanisms that alter chromatin to regulate gene ...

  

Source: Plotkin, Joshua B. - Department of Biology, University of Pennsylvania

 

Collection: Biology and Medicine


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61 Unwinding chromatin for development and growth: a few genes at a time
 

Summary:  Unwinding chromatin for development and growth: a few genes at a time Chang Seob Kwon1,2 and Doris... Sciences, KAIST, Daejeon 305-701, Korea SWI/SNF chromatin remodeling ATPases control accessibility... in mammals, flies and plants, have implicated chromatin remodeling ATPases in the regulation of many

  

Source: Plotkin, Joshua B. - Department of Biology, University of Pennsylvania

 

Collection: Biology and Medicine

 
62 THSE DE DOCTORAT En vue de l'obtention du grade de Docteur de l'Universit Paris-Sud XI
 

Summary:  -Pierre NORA Le 7 septembre 2011 Architecture chromosomique du locus Xic : implications pour la régulation de l... ARCHITECTURE CHROMOSOMIQUE DU LOCUS XIC : IMPLICATIONS POUR LA RÉGULATION DE L'INACTIVATION DU CHROMOSOME X Le... 'interaction s'intègre avec d'autres propriétés structurales du génome, tels la composition de la ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
63 Sabine M. Go risch Peter Lichter Karsten Rippe Mobility of multi-subunit complexes in the nucleus: accessibility
 

Summary:  coefficients of particles in the nucleus and chromatin loci Particle/locus rc (nm)a D (lm2 sÀ1 ) Reference Mx1... a The size of the region in which a given particle or the chromatin locus can translocate its centre of mass... , the chromatin locus mobility occurs ...

  

Source: Rippe, Karsten - BioQuant, Universität Heidelberg

 

Collection: Biology and Medicine

 
64 Cell, Vol. 44, 469-476, February 14, 1966, Copyright 0 1986 by Cell Press Genetic Analysis of the Proximal Portion of the
 

Summary:  to be described below place T66D distal to RP17.) Finally, the a-globin pseudogene- locus has been separated... of chromosome 17 and includes the T locus (defined by mutations that express both a recessive lethal pheno- type... that are closely linked to the T locus provides starting points for the eventual ...

  

Source: Silver, Lee - Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine ; Multidisciplinary Databases and Resources

 
65 Deletion and duplication of DNA sequences is associated with the
 

Summary:  by recombination in any of the BXD strains, they have been separated from the a-globin pseudogene 4 (Hba-4ps) locus... ; Sarvetnick et al. 1986), and the other is in the distal portion, spanning the interval be- tween the tf locus... obtained with probe p54M provided ev- idence that the D17Leh54 locus ...

  

Source: Silver, Lee - Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine ; Multidisciplinary Databases and Resources

 
66 Please cite this article in press as: Sang Y, et al. The stem cell--Chromatin connection. Semin Cell Dev Biol (2009), doi:10.1016/j.semcdb.2009.09.006
 

Summary:  Please cite this article in press as: Sang Y, et al. The stem cell--Chromatin connection. Semin... .elsevier.com/locate/semcdb Review1 The stem cell--Chromatin connection2 Yi Sang1 , Miin-Feng Wu1 , Doris Wagner 3 Department... Article history:8 Available online xxx 9 Keywords:10 Chromatin remodeling11 Histone modification12 Stem

  

Source: Plotkin, Joshua B. - Department of Biology, University of Pennsylvania

 

Collection: Biology and Medicine

 
67 dna repair 6 ( 2 0 0 7 ) 14961506 available at www.sciencedirect.com
 

Summary:  in chromatin remodeling YoungHo Kwona , Peter Chia , Dong Hyun Rohb , Hannah Kleinc , Patrick Sunga... 2007 Keywords: Rad51 Rad54 Chromatin remodeling D-loop Homologous recombination a b s t r a c t Rad54... , including the induction of topological changes in DNA and the remodeling of chromatin structure

  

Source: Roth, David B. - Langone Medical Center, New York University

 

Collection: Biology and Medicine

 
68 Metaphase chromosome condensation is a dynamic process that must utilize cis elements to form and maintain the final
 

Summary:  and maintain the final structure. Likewise, cis elements must regulate the accessibility of chromatin domains... sort of nuclear scaffold. This organization must permit dynamic movements of chromatin during... nuclear order and chromatin dynamics are achieved remain enigmatic. These biological processes

  

Source: Hart, Craig M. - Department of Biological Sciences, Louisiana State University

 

Collection: Biology and Medicine

 
69 Molecular Plant Volume 2 Number 4 Pages 600609 July 2009 REVIEW ARTICLE Chromatin Remodeling in Stem Cell
 

Summary:  gene encodes a hetero- chromatin protein 1 homolog and represses both FLOWERING LOCUS T to regulate... chromatin marks' at the silent AGAMOUS locus. Nucleic Acids Res. 35, 6290­6296. Saleh, A., et al. (2008... Molecular Plant · Volume 2 · Number 4 · Pages 600­609 · July 2009 REVIEW ARTICLE ...

  

Source: Krizek, Beth - Department of Biological Sciences, University of South Carolina

 

Collection: Biology and Medicine

 
70 Jennifer A.Armstrong, Ophelia Papoulas, Gary Daubresse1
 

Summary:  -g-induced chromatin remodeling at the CIITA locus is BRG1 dependent. EMBO J., 21, 1978±1986. Papoulas,O., Beek... the ATPase subunit of a 2 MDa complex that is related to yeast SWI/SNF and other chromatin... with nearly all transcriptionally active chromatin in a pattern that is generally non

  

Source: Scott, Matthew - Departments of Developmental Biology, Genetics, & Bioengineering, Stanford University

 

Collection: Biotechnology ; Biology and Medicine

 
71 N E W S A N D V I E W S Whether in animals, plants or fungi, the dis-
 

Summary:  - matin level. Silent chromatin is almost always associated with a methylated form of histone H3 (H3-Lys9... type locus (mat) could no longer be silenced5. A search for pro- teins mediating the interaction... - rochromatic domains: the pericentromeres, the telomeres and the mat locus. Pericentromeres and mat share

  

Source: 

 

Collection: Biology and Medicine

 
72 Dynamic Regulation of Histone H3 Methylated at Lysine 79 within a Tissue-specific Chromatin Domain*
 

Summary:  of the murine -globin locus. B, cross-linked chromatin was isolated from Me2SO-induced MEL cells. The relative... Dynamic Regulation of Histone H3 Methylated at Lysine 79 within a Tissue-specific Chromatin Domain... in mamma- lian chromatin are not known. We found that H3-meK79 has a variable distribution ...

  

Source: Bresnick, Emery H. - Molecular and Cellular Pharmacology Training Program & Department of Pharmacology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
73 Modulation of CTCF Insulator Function by Transcription of a Noncoding RNA
 

Summary:  of ncRNAs is required for chromatin remodeling at the fbp1+ locus in Schizosaccharomyces pombe during... to stabilize long-range chromatin contacts and organize chromosomes into higher- order complexes through... by concomitant alterations in chromatin structure within the upstream cis elements (Lefevre et ...

  

Source: Corces, Victor G. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
74 ROLES OF CHROMATIN REMODELING FACTORS IN THE FORMATION AND MAINTENANCE OF HETEROCHROMATIN STRUCTURE
 

Summary:  , as well as active ACT1 locus in the immunoprecipitated chromatin fragments was measured by PCR. Three... 1 on the primary chromatin structure of HML. (A) The HML locus. The HML-E and -I silencers and the 1... 1 ROLES OF CHROMATIN REMODELING FACTORS IN THE FORMATION AND MAINTENANCE OF ...

  

Source: Bi, Xin - Department of Biology, University of Rochester

 

Collection: Biology and Medicine

 
75 NATURE CELL BIOLOGY VOL 4 JULY 2002 http://cellbio.nature.com 502 Cajal Body dynamics and association
 

Summary:  and association with chromatin are ATP-dependent Melpomeni Platani*, Ilya Goldberg, Angus I. Lamond* and Jason R... association with chromatin and diffusion within the interchromatin space. CB mobility increases after ATP... depletion and inhibition of transcription, suggesting that the association of CB and chromatin requires ...

  

Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee

 

Collection: Biology and Medicine

 
76 Nucleus 1:3, 284-297; May/June 2010 2010 Landes Bioscience RESEARCH PAPER
 

Summary:  in animal and plant species (reviewed in refs. 1­5). Recently, the question of chromatin dynamics in nuclei... whether global chromosome order or at least the order of specific chromatin assemblies in trans can... /or chromatin loops is generated during interphase. Several groups have studied this problem in living cells

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
77 Immunity 24, 369379, April 2006 2006 Elsevier Inc. DOI 10.1016/j.immuni.2006.03.007 ReviewT Helper Cell Differentiation
 

Summary:  - fications is thought to demarcate ``active chromatin do- mains'' within a gene locus and is often associated... . Two Levels of a Poised Chromatin Configuration in the Th2 Cytokine Gene Locus (A) Schematic... locus, ex- erting its action on an already preformed, prepoised, ...

  

Source: Spilianakis, Charalampos G. "Babis" - Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology, Hellas

 

Collection: Biology and Medicine

 
78 The Journal of Experimental Medicine Volume 191, Number 6, March 20, 2000 10451050 Released online 20 March 2000
 

Summary:  and rearrangement from the TCR- locus (28). Transcription is thought to be an indicator of "open" chromatin, which... - locus in the chromatin of IL-7R / or Rag-2 / thymocytes before addition of the Rag proteins. However... chromatin accessibility at the TCR- locus. ...

  

Source: Schlissel, Mark S. - Department of Molecular and Cell Biology, University of California at Berkeley

 

Collection: Biology and Medicine

 
79 Histone Deacetylase-Dependent Establishment and Maintenance of Broad Low-Level Histone Acetylation within a Tissue-Specific Chromatin Domain
 

Summary:  major and minor and the upstream locus control region reside in hyperacetylated chromatin. Histone... locus, were not required for induction of H4 hyperacetylation. Analysis of chromatin structure within... acetylation functions at the level of chromatin domains in vivo. The -globin ...

  

Source: Bresnick, Emery H. - Molecular and Cellular Pharmacology Training Program & Department of Pharmacology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
80 Targeting chromatin remodelers: Signals and search mechanisms Fabian Erdel a
 

Summary:  maps iteratively for a certain genomic locus until a new steady state was reached [81]. Chromatin... is the targeting of a chromatin remodeler to a certain genomic locus like a promoter of a specific gene... Review Targeting chromatin remodelers: Signals and search mechanisms Fabian Erdel ...

  

Source: Rippe, Karsten - BioQuant, Universität Heidelberg

 

Collection: Biology and Medicine


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81 THEJOURNALOFCELLBIOLOGY The Rockefeller University Press $8.00
 

Summary:  Proteomic and genomic characterization of chromatin complexes at a boundary Alan J. Tackett,1 David J... cerevisiae genome that help define and preserve the boundaries that separate silent and active chromatin... . These assemblies contain characteristic stretches of DNA that flank particular regions of silent chromatin, as well

  

Source: Rout, Michael P. - Laboratory of Cellular and Structural Biology, Rockefeller University

 

Collection: Biology and Medicine

 
82 THEJOURNALOFCELLBIOLOGY The Rockefeller University Press $8.00
 

Summary:  Proteomic and genomic characterization of chromatin complexes at a boundary Alan J. Tackett,1 David J... cerevisiae genome that help define and preserve the boundaries that separate silent and active chromatin... . These assemblies contain characteristic stretches of DNA that flank particular regions of silent chromatin, as well

  

Source: Chait, Brian T. - Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University

 

Collection: Biology and Medicine

 
83 Leading Edge 1194 Cell 137, June 26, 2009 2009 Elsevier Inc.
 

Summary:  imprints, and (4) organization of locus-wide chromatin modifications. These data are consistent... : Active Chromatin Hub for Developmentally Regulated Activation The murine -globin locus has been... -bound regulatory sequences throughout the -globin locus come into spatial proximity to ...

  

Source: Corces, Victor G. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
84 Cell, Vol. 27, 239-240. December 1981 (Part l), Copyright 0 1981 by MIT Genetic Organization
 

Summary:  distal to the Tcpl locus. This result clearly indicates that t chromatin is not inherently defective... t complex (also known as the T locus or T/t complex) is a large region of chromosome 17 that has intrigued... systems is suppression of recombination over the localized region of chromatin encompassing

  

Source: Silver, Lee - Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine ; Multidisciplinary Databases and Resources

 
85 Chromatin profiling in model organisms Tony D. Southall and Andrea H. Brand
 

Summary:  Chromatin profiling in model organisms Tony D. Southall and Andrea H. Brand Abstract The correct... prevailing techniques for mapping protein^ chromatin interactions, ChIP (chromatin immunoprecipitation... chromatin structure and gene regulatory networks. In vivo chromatin profiling ...

  

Source: Brand, Andrea - Department of Genetics, University of Cambridge

 

Collection: Biology and Medicine

 
86 Copyright 2008 by the Genetics Society of America DOI: 10.1534/genetics.108.088732
 

Summary:  surveyincluded two closely linked a-globin genes, HBA-T1 and HBA-T2, that underlie adaptation to different... elevational zones. The primary goals were to assess whether the a-globin genes exhibit the hallmarks... a-globin gene and each of the three copies segregates functionally distinct alleles that exhibit

  

Source: Storz, Jay F. - School of Biological Sciences, University of Nebraska-Lincoln

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
87 ORIGINAL PAPER R. van Blokland M. ten Lohuis P. Meyer
 

Summary:  ORIGINAL PAPER R. van Blokland á M. ten Lohuis á P. Meyer Condensation of chromatin... silencing Received: 16 June 1997 / Accepted: 27 August 1997 Abstract The chromatin structures of two... chromatin to endonuc- leases. The two epialleles represented the active, hy- pomethylated state

  

Source: Meyer, Peter - Centre for Plant Sciences & Faculty of Biological Sciences, University of Leeds

 

Collection: Biology and Medicine

 
88 Many heme-binding proteins with diverse functions are known, including electron-transferring cytochromes,
 

Summary:  of both gene clusters requires tissue-specific activation of a chromatin domain regulated by a locus... no CpG islands, and the locus is in a DNAase-accessible, `open' chromatin conformation only in erythroid... , and the locus is in a constitutively `open' chromatin ...

  

Source: Hardison, Ross C. - Department of Biochemistry and Molecular Biology, Pennsylvania State University

 

Collection: Biology and Medicine

 
89 Histone Modifications within the Human X Centromere Brankica Mravinac1.
 

Summary:  repetitive regions have limited detailed studies of centromeric chromatin organization. However, a genomic... of a complex locus. We used ChIP to examine the distribution of modified histones within centromere regions... multiple chromatin characteristics. Partial truncation of the X centromere resulted in reduction

  

Source: Sullivan, Beth A. - Department of Genetics and Genomics, Boston University

 

Collection: Biology and Medicine

 
90 Chromatin Structure Regulates Gene W. Jason Cummings1
 

Summary:  sequences from an Figure 1. Chromatin Modification at the DT40 Igk Locus (A) Schematic diagram... upstream. The nonuniform chromatin structure of the locus suggests the presence of cis... the chromatin effects of LacI-HP1 were, we examined AcH3 and AcH4 levels throughout the Igk ...

  

Source: Maizels, Nancy - Department of Biochemistry, University of Washington at Seattle

 

Collection: Biology and Medicine

 
91 Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE
 

Summary:  repressor FLOWERING LOCUS C (FLC)1. Vernalization promotes flowering via epigenetic repression of FLC2... . Repression is accompanied by a series of histone modifications of FLC chromatin that include dimethylation... conditions typical of spring. LHP1 is enriched at FLC chromatin after prolonged exposure to cold, and LHP1

  

Source: Amasino, Richard M. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
92 10.1101/gad.6.12a.2288Access the most recent version at doi: 1992 6: 2288-2298Genes & Dev.
 

Summary:  .J N Hirschhorn, S A Brown, C D Clark, by altering chromatin structure. Evidence that SNF2/SWI2 and SNF... that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure Joel N. Hirschhorn... , Boston, Massachusetts 02115 USA Changes in chromatin structure have frequently been correlated

  

Source: Winston, Fred - Department of Genetics, Harvard University

 

Collection: Biology and Medicine

 
93 Saccharomyces cerevisiae Linker Histone Hho1p Functionally Interacts with Core Histone H4 and Negatively Regulates the
 

Summary:  chromatin (43­45). The abundance of sequences a­f as well as a control sequence at the ACT1 locus... and Negatively Regulates the Establishment of Transcriptionally Silent Chromatin* Received for publication... by the deletion of SIR1 that is involved in the establishment of silent chromatin at HML. We ...

  

Source: Bi, Xin - Department of Biology, University of Rochester

 

Collection: Biology and Medicine

 
94 www.landesbioscience.com Fly 1 Fly 4:3, 1-3; July/August/September 2010; 2010 Landes Bioscience
 

Summary:  (hb) transcription start site, and compared it to the chromatin structure of adam, a non-target locus... .landesbioscience.com/journals/fly/article/12200 Introduction In eukaryotes, DNA is packaged into chromatin, which imposes a natural barrier... of transcription, regulatory factors recruit chromatin ...

  

Source: Arnosti, David N. - Department of Biochemistry and Molecular Biology, Michigan State University

 

Collection: Biology and Medicine

 
95 24. K. D. Irvine, C. Rauskolb, Annu. Rev. Cell Dev. Biol. 17, 189 (2001).
 

Summary:  lineage has not been previously assessed. HbF is a tetramer of two adult a-globin poly- peptides and two... within the BCL11A locus with HbF levels in disparate populations (5­7, 10), we explore here... the hypothesis that the product of the BCL11A locus, a multi­zinc finger transcription factor, encodes a stage

  

Source: Lycan, Deborah E. - Department of Biology, Lewis and Clark College

 

Collection: Biology and Medicine

 
96 Allele-specific and heritable chromatin signatures Ewan Birney1,
 

Summary:  Allele-specific and heritable chromatin signatures in humans Ewan Birney1, , Jason D. Lieb2... the analysis of individual-to-individual and allele-specific variation of chromatin status and transcription... cell lines. Around 10% of chromatin sites show either individual-level differences or allele

  

Source: Iyer, Vishy - Institute for Cellular and Molecular Biology, University of Texas at Austin

 

Collection: Biotechnology ; Biology and Medicine

 
97 Plant Molecular Biology 43: 221234, 2000. M.A. Matzke and A.J.M. Matzke (Eds.), Plant Gene Silencing.
 

Summary:  silencing and chromatin components Peter Meyer Centre for Plant Science, Leeds Institute for Plant... -mail: P.Meyer@Leeds.ac.uk) Key words: chromatin remodelling, DNA methylation, epigenetics, heterochromatin... is embedded in a highly complex chromatin structure that controls the location and accessibil- ity

  

Source: Meyer, Peter - Centre for Plant Sciences & Faculty of Biological Sciences, University of Leeds

 

Collection: Biology and Medicine

 
98 Cell, Vol. 116, 683698, March 5, 2004, Copyright 2004 by Cell Press From Silencing to Gene Expression
 

Summary:  without any The Kinetics of Chromatin Decondensation particular enrichment at the locus (Figure 2B... of a region of chromatin within the array that Though the locus is still compact 5 min postinduction, forms... in chromatin structure (Supplemental Data,at the condensed ...

  

Source: Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
99 Regulation of chromatin structure by histone H3S10 phosphorylation Kristen M. Johansen* & Jrgen Johansen
 

Summary:  Regulation of chromatin structure by histone H3S10 phosphorylation Kristen M. Johansen* & Jørgen... -mail: kristen@iastate.edu *Correspondence Key words: chromatin, Drosophila, histone code, histone H3S10... association with two apparently opposed chromatin states. It is found at elevated levels on the highly

  

Source: Johansen, Kristen M - Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University

 

Collection: Biology and Medicine

 
100 Joanna M. Bridger and Emanuela V. Volpi (eds.), Fluorescence in situ Hybridization (FISH): Protocols and Applications, Methods in Molecular Biology, vol. 659,
 

Summary:  .1007/978-1-60761-789-1_7, © Springer Science+Business Media, LLC 2010 Chapter 7 Optical Mapping of Protein­DNA Complexes on Chromatin... nuclei. Using these techniques, the locations of whole chromosome territories, chromatin subdomains... of the spatial relationships of proteins and DNA can be achieved using combined IF-FISH on extended ...

  

Source: Sullivan, Beth A. - Department of Genetics and Genomics, Boston University

 

Collection: Biology and Medicine


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