| Sample search results for: abbott prism hcv |
| 1 | Hepatitis C Virus (HCV) Genotype 1 Subtype Identification in New HCV Drug Development and Future | ||
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Summary: by Siemens Medical Solutions Diagnostics. The Abbott RealTime HCV Genotype II kits were kindly provided... -LiPA HCV 1.0 INNO-LiPA HCV 2.0 Abbott RealTime HCV Genotype II assay Manufacturer Siemens Medical Solutions... to identify the HCV subtype ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 2 | PERFORMANCE OF THE ABBOTT m2000SP/m2000RT REAL-TIME POLYMERASE CHAIN REACTION ASSAY FOR HEPATITIS C VIRUS | ||
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Summary: performance of m2000SP/m2000RT, the Abbott real-time PCR platform for HCV RNA quantification. The study shows... in clinical practice. In conclusion, our study shows that the Abbott m2000 real- time PCR system for HCV RNA... and clinical performances of the recently developed Abbott ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 3 | Influence of Alcohol Use, Race, and Viral Coinfections on Spontaneous HCV Clearance | ||
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Summary: was determined using second- and third-generation enzyme- linked immunosorbent assays (Abbott HCV EIA 2.0 and 3... Influence of Alcohol Use, Race, and Viral Coinfections on Spontaneous HCV Clearance in a US Veteran... . Porter,1 Robert M. Weinrieb,1,2 Donald D. Stieritz,2 and Kyong-Mi Chang1,2 Hepatitis C virus ... |
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Source: Bellamy, Scarlett - Department of Biostatistics and Epidemiology, University of Pennsylvania |
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Collection: Biology and Medicine |
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| 4 | Journal of Medical Virology 82:263270 (2010) Hepatitis C Infection Among Intravenous Drug | ||
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Summary: , the Netherlands The most high-risk population for HCV trans- mission worldwide today are intravenous drug users... . HCV genotypes in the general population in Cyprus demonstrate a polyphyletic infection and include... subtypes associated with intravenous drug users. The prevalence of HCV, HBV, and HIV infection, ... |
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Source: |
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Collection: Biology and Medicine |
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| 5 | Fang et al. Host cell responses induced by HCV Host Cell Responses Induced by Hepatitis C Virus Binding | ||
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Summary: LIA (Abbott). Liver biopsy histology of HCV-infected individuals revealed mild inflammatory activity (grade 1... Fang et al. Host cell responses induced by HCV 1 Host Cell Responses Induced by Hepatitis C Virus... : Host cell responses induced by HCV Keywords: virus-host interaction, receptor, signalling, ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 6 | Expression of hepatitis C virus proteins in epithelial intestinal cells in vivo Short title: HCV protein expression in intestine | ||
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Summary: Expression of hepatitis C virus proteins in epithelial intestinal cells in vivo Short title: HCV... " and by a "contrat de collaboration INSERM-bioMérieux". Abbreviations: HCV, hepatitis C virus; LVP, lipo... Virol 2004;85(Pt 9):2515-23 #12;2 Abstract Previous work on hepatitis C virus (HCV) led to the discovery |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 7 | Synonymous Mutations in the Core Gene Are Linked to Unusual Serological Profile in Hepatitis C Virus Infection | ||
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Summary: generation microparticle enzyme immunoassay (MEIA) (AxSYM HCV, version 3.0; Abbott, Wiesbaden, Germany). Anti-HCV... virus (HCV) genome remains elusive, as does the significance of the production of corresponding... antibodies in HCV infection. We investigated the prevalence of anti-core ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 8 | JOURNAL OF CLINICAL MICROBIOLOGY, Oct. 1996, p. 25522558 Vol. 34, No. 10 0095-1137/96/$04.00 0 | ||
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Summary: method with primers specific for the 3 noncoding region (NCR) of hepatitis C virus (HCV) has been... conserved sequence at the 3 terminus of the HCV genome. Direct sequencing of the PCR products confirmed... HCV genome equivalents). To evaluate specificity and sensitivity, a panel of 116 serum samples |
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Source: Cavalli-Sforza, Luigi - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 9 | Hepatitis C Virus Controls Interferon Production through PKR Activation | ||
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Summary: -induction pathway. Low IFN induction has been attributed to HCV NS3/4A protease-mediated cleavage... of the mitochondria-adapter MAVS. Here, we have investigated the early events of IFN induction upon HCV infection... , using the cell-cultured HCV JFH1 strain and the new HCV-permissive hepatoma-derived ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 10 | Revised MT-2006-115 Inhibition of hepatitis C virus infection in cell culture by small interfering RNAs | ||
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Summary: @pasteur.fr Short title: Silencing of hepatitis C virus infection * Manuscript #12;2 ABSTRACT Hepatitis C virus (HCV... process mediated by small interfering RNA (siRNA) duplexes, as an antiviral strategy for HCV. Synthetic si... RNAs were designed to target conserved sequences of the HCV 5' nontranslated region located in a ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 11 | Host Cell Responses Induced by Hepatitis C Virus Binding | ||
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Summary: Corpora- tion Diagnostic, Tarrytown, NY) and anti-HCV antibodies using Anti-HCV-IgG ChLIA (Abbott Labora... - tories, Abbott Park, IL). Liver biopsy histology of HCV- infected individuals revealed mild inflammatory... . Blum,1 and Thomas F. Baumert1,5 Initiation of hepatitis C virus ... |
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Source: Timmer, Jens - Freiburger Zentrum für Datenanalyse und Modellbildung & Physikalisches Institut, Albert-Ludwigs-Universität Freiburg |
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Collection: Physics |
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| 12 | Liver Cancer-Derived Hepatitis C Virus Core Proteins Shift TGF-Beta Responses from Tumor Suppression to | ||
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Summary: , Florence, Italia, 6 Inserm Unite´ 673, Paris, France Abstract Background: Chronic hepatitis C virus (HCV... - derived HCV core natural variants on cancer progression through their impact on TGF-b signaling. Principal... activation dictate the TGF-b responses in hepatic cells and that HCV core protein, by decreasing Smad3 |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 13 | P. Ferraris et al. HCV-associated host cell membranes page 1 Journal of General Virology 2010 Sep;91(Pt9): 2230-2237 | ||
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Summary: then analyzed for the presence of HCV RNA and proteins. Viral RNA was quantified with the Abbott m2000sp-m2000rt... gradient. (A): HCV RNA, represented here in millions of IU/ml (Abbott m2000sp-m2000rt real-time PCR assay... P. Ferraris et al. HCV-associated host cell membranes page 1 ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 14 | Best Pract Res Clin Gastroenterol . Author manuscript Diagnosis and management of chronic viral hepatitis: antigens, antibodies | ||
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Summary: , are chronically infected with hepatitis B virus (HBV) or hepatitis C virus (HCV) , . Each year, over 1,5 million... people die from HBV- and/or HCV-related chronic liver diseases, such as1 2 end-stage cirrhosis... and hepatocellular carcinoma (HCC). HCC is one of the most common cancers worldwide and in 2002, HBV and HCV have |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 15 | Diagnosis and Management of Chronic Viral Hepatitis: Antigens, Antibodies and Viral | ||
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Summary: , are chronically infected with hepatitis B virus (HBV) or hepatitis C virus (HCV) 1, 2. Each year, over 1,5 million... people die from HBV- and/or HCV-related chronic liver diseases, such as end-stage cirrhosis... and hepatocellular carcinoma (HCC). HCC is one of the most common cancers worldwide and in 2002, HBV and HCV have |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 16 | Hepatitis C Virus Reveals a Novel Early Control in Acute Immune Response | ||
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Summary: virus (HCV) results in poor production of IFN despite recognition of the viral RNA by RIG-I but can lead... to induction of early ISGs. HCV was shown to inhibit IFN production by cleaving MAVS through its NS3/4A... RNA-binding domains (DRBD). Here, we have identified a third mode of control of IFN induction by HCV. Using HCVcc |
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Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique |
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Collection: Physics |
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| 17 | Title: Chronic hepatitis C virus infection: does it really impact health-related quality of life? A study in rural Egypt. | ||
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Summary: - Ghent, Belgium; and ABBOTT HCV EIA 3.0, 3rd generation test - Abbott Laboratories - Wiesbaden, Delknheim... Pasteur, Paris, France. Keywords: HCV, SF-12, Visual analogue scale, disease labelling effect, Developing... aminotransferase CHC: chronic hepatitis C HCV: Hepatitis C virus ... |
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Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique |
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Collection: Physics |
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| 18 | JOURNAL OF VIROLOGY, 0022-538X/00/$04.00 0 | ||
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Summary: /Accepted 18 August 2000 The hepatitis C virus (HCV) internal ribosome entry site (IRES) is a highly... antisense oligonucleotides directed to- wards stem loop IIId drastically reduced HCV IRES activity... comparison showed that apical loop nucleotides (UUGGGU) were absolutely conserved across HCV genotypes |
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Source: Doudna, Jennifer A. - Department of Molecular and Cell Biology, University of California at Berkeley |
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Collection: Biology and Medicine |
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| 19 | Revised manuscript JMVir/2003/5692 Genetic variability of hepatitis C virus in chronically infected patients with | ||
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Summary: de l'Hôpital, 69288 LYON cedex 02, France Running title: HCV breakthrough during antiviral therapy... (HCV) breakthrough during antiviral therapy, although it would help in understanding HCV resistance... responses against HCV epitopes were also analysed. The major sequences of IRES, PePHD and NS5B remained |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 20 | MA THELU -18/02/2010 J Medical Virology 1 IRES Complexity before IFN-alpha treatment and | ||
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Summary: of HCV replication. The viral load mainly reflects the degradation rate of the viruses. However... , differences in the behaviour of the viral population depend on changes which occurred in the HCV-IRES genome... the PBMCs of eighteen patients (5 women, 13 men) with chronic hepatitis C. The HCV IRES appeared |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 21 | Bio-Rad Laboratories I n f e c t I O u s D I s e a s e c O n t R O L s Assayed VIROTROL | ||
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Summary: HepatitisCVirus,andantibodiestoHepatitisBcoreAntigen . Analytes HBsAg Anti-HIV-1 Anti-HCV Anti-HBc Anti-HTLV-I* Anti-CMV* Assayed VIROTROL® I-E Most suitable... for use with Roche Elecsys® /MODULAR Systems Assayed VIROTROL® I-F Most suitable for use with Abbott Ax... -HAV ... |
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Source: Rodriguez, Carlos - Department of Mathematics and Statistics, State University of New York at Albany |
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Collection: Mathematics ; Physics |
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| 22 | The new engl and jour nal of medicine n engl j med 360;18 nejm.org april 30, 2009 1839 | ||
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Summary: article Telaprevir and Peginterferon with or without Ribavirin for Chronic HCV Infection Christophe Hézode... In patients with chronic infection with hepatitis C virus (HCV) genotype 1, treatment with peginterferon alfa... is a specific inhibitor of the HCV serine pro- tease and could be of value in HCV ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 23 | ForPeerReview Liver Stiffness Diminishes with Antiviral Response in | ||
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Summary: on HCV Therapy Corresponding author: Prof. Jean-Michel Pawlotsky, MD, PhD, Department of Virology... 2011 #12;ForPeerReview 4 Chronic infection with hepatitis C virus (HCV) is the leading cause of chronic... .1 Nowadays, HCV is becoming the first cause of primary liver cancer and is the main indication |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 24 | JOURNAL OF VIROLOGY, 0022-538X/01/$04.00 0 DOI: 10.1128/JVI.75.3.13481358.2001 | ||
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Summary: proteins that can bind the 3 untranslated region (UTR) of hepatitis C virus (HCV) we screened human c... from the 3 -terminal 98 nucleotides (3 X region) of an infectious clone of HCV (H77c) yielded clones... predicted secondary structure to the HCV 3 X, assemble into ribonucleoprotein particles that include L22 |
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Source: Fields, Stan - Department of Genome Sciences, University of Washington at Seattle |
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Collection: Biology and Medicine |
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| 25 | University of the Joseph Fourier-Grenoble UFR of Biology | ||
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Summary: & HCV 26 Hepatocarcinogenesis 26 Cirrhotic nodules as a pre-neoplastic lesion 27 Molecular pathways... in the normal and cHCV infected liver 65 Initial capture or adhesion 65 Triggering and arrest of lymphocytes... Clinicopathological study of the Intra-hepatic lymphocytes populations during HCV related Hepatocellular ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 26 | ForPeerReview Morphological Changes in Intracellular Lipid Droplets Induced by Different | ||
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Summary: -mail: jean-michel.pawlotsky@hmn.aphp.fr Abbreviations: HCV: hepatitis C virus; BMI: body mass index; HOMA... virus (HCV) infection. Steatosis is a cofactor for fibrosis and disease progression in chronic hepatitis... regardless of the HCV genotype, including the body mass index (BMI), hyperlipidemia, type 2 diabetes |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 27 | Center for Viral Hepatitis NIH Center for Molecular Studies in Digestive & Liver Diseases | ||
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Summary: Center for AIDS Research Inaugural Symposium "HCV: Natural History, Pathogenesis and Therapy with... Cancer Ctr., University of N. Carolina at Chapel Hill "Virology of HCV" 9:20 David L. Thomas, MD, MPH... History/Epidemiology of HCV, HIV and Co-Infection" 10:00 John G. McHutchison, MD Senior Vice President |
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Source: Bushman, Frederic - Department of Microbiology, University of Pennsylvania |
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Collection: Biology and Medicine |
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| 28 | Silibinin mode of action(s) against HCV: A controversy yet to be resolved Harel Dahari1,2 | ||
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Summary: 1 Silibinin mode of action(s) against HCV: A controversy yet to be resolved Harel Dahari1... inhibit HCV NS5B RNA- dependent RNA polymerase (RdRp) activity. Here we note the HCV kinetics observed... in patients treated with SIL2-4 and the HCV-RdRp inhibitor RG7128 (5 and manuscript in preparation) have |
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Source: Ahlers, Guenter - Department of Physics, University of California at Santa Barbara |
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Collection: Physics |
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| 29 | Future Microbiol . Author manuscript HCV entry and neutralizing antibodies: lessons from viral variants | ||
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Summary: Future Microbiol . Author manuscript Page /1 5 HCV entry and neutralizing antibodies: lessons from... infection despite the presence of anti-HCV antibodies. A prerequisite of the understanding of the mechanisms... factors mediating the first steps of viral infection: binding and entry of HCV is believed to be a multi |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 30 | Hepatology. Author manuscript Host neutralizing responses and pathogenesis of hepatitis C virus | ||
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Summary: steps of hepatitis C virus (HCV) infection has rapidly advanced our knowledge of antibody-mediated virus... of host neutralizing responses during the course of HCV infection. It focuses on recent studies in HCV... The hepatitis C virus (HCV) is a small enveloped positive-strand RNA virus that belongs to the ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 31 | JOURNAL OF VIROLOGY, Dec. 1996, p. 87828791 Vol. 70, No. 12 0022-538X/96/$04.00 0 | ||
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Summary: /Accepted 9 August 1996 Hepatitis C virus (HCV), a positive-strand RNA virus, is the major infectious agent... responsible for causing chronic hepatitis. Currently, there is no vaccine for HCV infection, and the only... to the management of HCV infection, six hammerhead ribozymes directed against a conserved region of the plus ... |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 32 | Histochem Cell Biol 2008 DOI 10.1007/s00418-008-0447-2 PMID 18512067. | ||
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Summary: -mail: roingeard@med.univ-tours.fr Abstract The mechanisms underlying hepatitis C virus (HCV) morphogenesis remain... investigated the interaction between HCV-like particles and lipid droplets by three-dimensional reconstructions... of serial ultrathin electron microscopy sections of cells producing the HCV core protein. The ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 33 | Cellular cofactors affecting hepatitis C virus infection and replication | ||
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Summary: for review February 28, 2007) Recently identified hepatitis C virus (HCV) isolates that are infectious... in cell culture provide a genetic system to evaluate the significance of virushost interactions for HCV... encoding proteins that physically interact with HCV RNA or proteins or belong to cellular pathways thought |
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Source: Bergstrom, Carl T. - Department of Biology, University of Washington at Seattle |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 34 | J Innate Immun . Author manuscript Toll-like receptor 2 senses hepatitis C virus core protein but not infectious | ||
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Summary: to purified recombinant HCV structural proteins and enveloped virus-like particles. Incubation of TLR2 or TLR4... . In contrast, neither infectious virions nor enveloped HCV-like particles triggered TLR2 and TLR4 signaling... . These findings suggest that monomeric HCV core protein but not intact infectious particles are sensed by ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 35 | Characterization of the Specific CD4+ T Cell Response | ||
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Summary: virus (HCV) Alternate Reading Frame Protein (ARFP or F protein) presents a double-frame shift product... of the HCV core gene. We and others have previously reported that the specific antibodies against the F... protein could be raised in the sera of HCV chronically infected patients. However, the specific CD4 |
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Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique |
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Collection: Physics |
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| 36 | Castera et al. Hepatic steatosis in HIV-HCV coinfected patients in France: comparison with HCV | ||
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Summary: Castera et al. 1 Hepatic steatosis in HIV-HCV coinfected patients in France: comparison with HCV... monoinfected patients matched for body mass index and HCV genotype L. CASTÉRA (1, 2), M. A. LOKO (3), B. LE... .castera@chu-bordeaux.fr Short title: Hepatic steatosis in HIV-HCV and matched ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 37 | Potential impact of vaccination on the hepatitis C virus epidemic in injection Judith A. Hahn a, | ||
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Summary: vaccine Background: Hepatitis C virus (HCV) causes significant morbidity and mortality in injecting drug... users (IDU) worldwide. HCV vaccine candidates have shown promise for reducing the infectivity of acute... delivery strategies on the HCV epidemic in IDU has not been explored. Methods: We utilized extensive data |
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Source: Grether, Gregory - Department of Ecology and Evolutionary Biology, University of California at Los Angeles |
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Collection: Environmental Sciences and Ecology |
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| 38 | Expert Rev Vaccines . Author manuscript Development of hepatitis C virus vaccines: challenges and progress | ||
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Summary: of an effective vaccine against hepatitis C virus (HCV) has long been defined as a difficult challenge due... ; immunology ; Viral Vaccines ; immunology Author Keywords antibody ; HCV ; chimpanzee model ; therapeutic... with HCV and 3 to 4 million individuals are newly infected each year .[1 ] Region-specific estimates of ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 39 | Priority Paper Evaluation Hepatitis C virus entry and neutralizing antibodies: lessons from | ||
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Summary: infection despite the presence of anti-HCV antibodies. A prerequisite of the understanding of the mechanisms... factors mediating the first steps of viral infection: binding and entry of HCV is believed to be a multi... -step process involving HCV envelope glycoproteins E1 and E2 as well as several host cell surface molecules |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 40 | GUT/2006/108647-Revised Page 1 GUT 2007, 56, 1302-1308. | ||
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Summary: , France. Running title: HCV genotype 3-specific steatosis Keywords: HCV, genotype, steatosis, lipid... droplet Abbreviations: HCV, hepatitis C virus; ER, endoplasmic reticulum; SPP, signal peptide peptidase... hepatitis C virus (HCV) than in patients infected with other genotypes. HCV ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 41 | RNA Interference and Single Particle Tracking Analysis of Hepatitis C Virus Endocytosis | ||
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Summary: (HCV) enters hepatocytes following a complex set of receptor interactions, culminating... the cellular molecular requirements for infectious HCV entry. Therefore, we analyzed a siRNA library... that targets 140 cellular membrane trafficking genes to identify host genes required for infectious HCV |
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Source: Bergstrom, Carl T. - Department of Biology, University of Washington at Seattle; Chicago, University of - Department of Microbiology |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 42 | HCV core, lipid droplets and steatosis -Page 1 Journal of Viral Hepatitis 2008, 15, 157-164 | ||
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Summary: HCV core, lipid droplets and steatosis - Page 1 Journal of Viral Hepatitis 2008, 15, 157-164 REVIEW... , Université François Rabelais & CHRU de Tours, 10 boulevard Tonnellé 37032 Tours, France. Running head: HCV... in "Journal of Viral Hepatitis 2008;15:157-164" DOI : 10.1111/j.1365-2893.2007.00953.x #12;HCV core, lipid |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 43 | Hoffmann and Zeisel et al. HCV Structural Proteins and TLR2 Toll-like Receptor 2 Senses Hepatitis C Virus Core Protein But Not1 | ||
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Summary: Hoffmann and Zeisel et al. HCV Structural Proteins and TLR2 1 Toll-like Receptor 2 Senses Hepatitis... to this work15 16 Running title: HCV structural proteins and TLR217 18 Corresponding author: Thomas F. Baumert... ;Hoffmann and Zeisel et al. HCV Structural Proteins and TLR2 2 ABSTRACT1 Toll-like receptors (TLRs |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 44 | Dean's Corner Nancy B. Schwartz, PhD | ||
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Summary: persistent viral infection. Specifically, his research is focused on the role of hepatitis C virus (HCV... )-host interactions in viral replication and pathogenesis. An examination of the roles of host genes in HCV... -Champaign. After an internship at Abbott Laboratories, he pursued graduate studies at the University of Chicago |
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Source: Chicago, University of - Department of Microbiology |
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Collection: Biology and Medicine |
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| 45 | [Communicative & Integrative Biology 2:6, 1-3; November/December 2009]; 2009 Landes Bioscience 1 Communicative & Integrative Biology 2009; Vol. 2 Issue 6 | ||
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Summary: infected with hepatitis C virus (HCV). New antiviral treatment strate- gies are needed due to limitations... genes in HCV infection and replication and identified several cellular co-factors for viral replication... . Phosphatidylinositol 4-kinase III alpha (PI4K-III) was found to be essential for HCV replication. PI4K-III co |
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Source: Chicago, University of - Department of Microbiology |
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Collection: Biology and Medicine |
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| 46 | Cancer Res . Author manuscript Downregulation of Gadd45beta expression by hepatitis C virus leads to | ||
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Summary: in several human cancers including hepatocellular carcinomas. Chronic infection by hepatitis C virus (HCV... and HCV infection. Inhibited Gadd45 expression was observed in both non-tumoral and tumoral tissues from... infected individuals, and in cell lines harboring an HCV replicon and the infectious HCV ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 47 | Host Neutralizing Responses in Hepatitis C Virus Infection Mirjam B. Zeisel1, 2 | ||
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Summary: ;Abstract Hepatitis C virus (HCV) is a major cause of hepatitis world-wide. The majority of infected... systems for HCV entry and infection has finally allowed to study antibody-mediated neutralization... has enabled to study neutralizing responses in the course of HCV infection and characterize the impact |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 48 | Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha | ||
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Summary: ) Hepatitis C virus (HCV) reorganizes cellular membranes to establish sites of replication. The required host... -trafficking genes to identify genes required for both HCV subgenomic replication and infectious virus production. We... are required for HCV replication. We found extensive co-localization of the ... |
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Source: Bergstrom, Carl T. - Department of Biology, University of Washington at Seattle |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 49 | Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha | ||
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Summary: ) Hepatitis C virus (HCV) reorganizes cellular membranes to establish sites of replication. The required host... -trafficking genes to identify genes required for both HCV subgenomic replication and infectious virus production. We... are required for HCV replication. We found extensive co-localization of the ... |
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Source: Chicago, University of - Department of Microbiology |
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Collection: Biology and Medicine |
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| 50 | Intensity of Schistosoma Mansoni, Hepatitis B, Age, and Sex Predict Levels of Hepatic Periportal Thickening/Fibrosis (PPT/F): A Large-Scale Community-Based Study | ||
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Summary: ), and reactive samples were cross-checked using Architect Anti-HCV test kits (Abbott Laboratories, Chicago, IL... HBsAg positive, and 1.3% were anti-hepatitis C virus (HCV) positive. Prevalence of PPT/F increased... with lower odds for PPT/F. HCV was not associated with S. mansoni infection or with ... |
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Source: Arnold, Jonathan - Nanoscale Science and Engineering Center & Department of Genetics, University of Georgia |
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Collection: Biotechnology |
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| 51 | Hepatology . Author manuscript Seroconversion to hepatitis C virus alternate reading frame protein during | ||
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Summary: . Several mechanisms of production have been postulated and the function(s) of these proteins in the HCV... . Three of these patients were infected by one of the two HCV strains, whereas the strain infecting... seroconversion in some but+ not all of the patients infected by one of the HCV strains, and no such difference |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 52 | HEPATITIS C VIRUS (HCV) PROTEINS INDUCE LIPOGENESIS AND DEFECTIVE TRIGLYCERIDE SECRETION IN TRANSGENIC MICE EXPRESSING THE HCV FULL- | ||
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Summary: 1 HEPATITIS C VIRUS (HCV) PROTEINS INDUCE LIPOGENESIS AND DEFECTIVE TRIGLYCERIDE SECRETION... IN TRANSGENIC MICE EXPRESSING THE HCV FULL- LENGTH OPEN READING FRAME. Hervé Lerat1 , Hélène L. Kammoun2... , Université Paris 12, Créteil, France4 Running head: Lipogenesis and triglyceride secretion in HCV mice |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 53 | Journal of General Virology 2006 Core Protein Cleavage by Signal Peptide Peptidase is Required for | ||
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Summary: Médecine & CHU, 10 boulevard Tonnelle, 37032 Tours, France. Running title: HCV core protein cleavage by SPP... equally to this work. SUMMARY Hepatitis C virus (HCV) core protein, expressed with a Semliki forest virus... (SFV) replicon, self-assembles into HCV-like particles (HCV-LP) at the endoplasmic ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 54 | J Biol Chem . Author manuscript Hepatitis C virus proteins induce lipogenesis and defective triglyceride | ||
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Summary: hepatitis C virus (HCV) infection is associated with altered lipid metabolism and hepatocellular steatosis... . Virusinduced steatosis is a cytopathic effect of HCV replication. The goal of this study was to examine... the mechanisms underlying HCV-induced lipid metabolic defects in a transgenic mouse model expressing the full ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 55 | Characterization of a canine homolog of hepatitis C virus | ||
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Summary: % of the world's population is chronically infected with hepatitis C virus (HCV). Although HCV was discovered... has been identified; furthermore, efforts to understand HCV pathogenesis have been hampered... ) confirmed it to be the most geneti- cally similar animal virus homolog of HCV. Bayesian Markov chains ... |
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Source: Columbia University - Jerome L. and Dawn Greene Infectious Disease Laboratory |
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Collection: Biology and Medicine |
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| 56 | HEPATITIS C VIRUS ENTRY: MOLECULAR MECHANISMS AND TARGETS FOR ANTIVIRAL THERAPY Mirjam B. Zeisel1,2,3 | ||
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Summary: OF CONTENTS 1. Abstract 2. Introduction 3. Molecular mechanisms of HCV entry into target cells 3.1. Viral... .2.2.1. Tetraspanins: CD81 and claudin-1 3.2.2.2. Scavenger receptor SR-BI 3.2.2.3. LDL receptor 3.3. Mechanisms of HCV... infected individuals, hepatitis C virus (HCV) has a major impact on public health. The liver is the ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 57 | This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research | ||
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Summary: Available online 10 September 2009 Keywords: HCV Lovastatin PPARalpha Viral replication CARS imaging Here we... of hepatitis C virus (HCV) RNA using two-photon fluorescence (TPF) and coherent anti-Stokes Raman scattering... the dispersion of HCV RNA from replication sites and simultaneously induce lipid storage and increases in ... |
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Source: Xie, Xiaoliang Sunney - Department of Chemistry and Chemical Biology, Harvard University |
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Collection: Chemistry ; Biotechnology |
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| 58 | Front Biosci . Author manuscript Hepatitis C virus entry: molecular mechanisms and targets for antiviral | ||
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Summary: .baumert@unistra.fr > Abstract With an estimated 170 million infected individuals, hepatitis C virus (HCV) has a major impact... on public health. The liver is the primary target organ of HCV, and the hepatocyte is its primary target... into the cell and initiation of infection. Using recombinant HCV envelope glycoproteins and ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 59 | Scavenger Receptor BI Is a Key Host Factor for Hepatitis C Virus Infection Required for an Entry Step Closely Linked to CD81 | ||
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Summary: integrin; HCV: hepatitis C virus; HCVcc: cell culture-derived HCV; HCVpp: HCV pseudotype particles; HDL... Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. Scavenger receptor class B type I... (SR-BI) has been shown to bind HCV envelope glycoprotein E2, ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 60 | 1998 7: 605-610Protein Sci. S. KOROLEV, N. YAO, T. M. LOHMAN, P. C. WEBER and G. WAKSMAN | ||
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Summary: of HCV and Rep helicases References http://www.proteinscience.org/cgi/content/abstract/7... . Printed in the USA. Copyright 0 1998 The Protein Society Comparisons between the structures of HCV and Rep... similar. In contrast, the HCV helicase belongs to a different super-family of helicases, SF2, and shows |
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Source: Cistola, David P. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis; Lohman, Timothy M. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 61 | High-Dose Pegylated Interferon Alfa and Ribavirin in Non-responder Hepatitis C Patients and Relationship with IL28B Genotype (SYREN Trial) | ||
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Summary: -IFN and Ribavirin and IL28B in HCV nonresponders *These two authors equally contributed to the work Corresponding... is investigator-initiated. It has been funded by Roche France, which provided the study drugs. Abbreviations: HCV... treatment failure and HCV resistance when combined with direct acting antivirals. The influence ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 62 | TheJournalofExperimentalMedicine J. Exp. Med. The Rockefeller University Press 0022-1007/2003/03/633/10 $8.00 | ||
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Summary: of hepatitis C virus (HCV), a major cause of chronic liver disease, has been ham- pered by the lack of a cell... -particles that were assembled by displaying unmodified and func- tional HCV glycoproteins onto retroviral... and lentiviral core particles. The presence of a green fluorescent protein marker gene packaged within these ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 63 | Molina et al., LDLR and HCV infection of normal hepatocyte 1 The Low Density Lipoprotein Receptor plays a role in the | ||
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Summary: Molina et al., LDLR and HCV infection of normal hepatocyte 1 The Low Density Lipoprotein Receptor... title : LDLR and HCV infection of normal hepatocyte Corresponding author: Patrick Maurel, Inserm U632... .09.024 #12;Molina et al., LDLR and HCV infection of normal hepatocyte 2 Abstract Background/Aims: The direct |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 64 | JOURNAL OF VIROLOGY, Nov. 2006, p. 1057910590 Vol. 80, No. 21 0022-538X/06/$08.00 0 doi:10.1128/JVI.00941-06 | ||
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Summary: of hepatitis C virus (HCV) are the first steps of viral infection and represent a major target for antiviral... a key role in the binding of HCV envelope glycoprotein E2 to target cells (Barth et al., J. Biol. Chem... . 278:4100341012, 2003). In this study, we characterized the HCV-HS interaction and analyzed its |
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Source: Linhardt, Robert J. - Center for Biotechnology and Interdisciplinary Studies & Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute |
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Collection: Biotechnology ; Chemistry |
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| 65 | Peptide-protein microarrays and surface plasmon resonance detection: biosensors for versatile biomolecular interaction analysis | ||
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Summary: , France) and Merck (Paris, France) respectively. A97, a polypeptide from hepatitis C virus (HCV) Alternate... ) derived from Ovalbumin (Ova), HCV and hepatitis D virus (HDV) were synthesized with a pyrrole-modified NH2... ) was provided by J.-P. Lavergne. Human serums from healthy donors (n=2), HCV- infected patients (n=4) and HDV |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 66 | DOI: 10.1002/cbic.200600330 Intracellular Imaging of HCV RNA | ||
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Summary: DOI: 10.1002/cbic.200600330 Intracellular Imaging of HCV RNA and Cellular Lipids by Using... ,[a] Angela M. Tonary,[b] Albert Stolow,[b] X. Sunney Xie,[a] and John Paul Pezacki*[b] The propagation of HCV... ,2] Genotypes 1a and 1b of HCV induce changes in lipid metabo- lism[34] and cause the formation of endoplasmic |
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Source: Xie, Xiaoliang Sunney - Department of Chemistry and Chemical Biology, Harvard University |
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Collection: Chemistry ; Biotechnology |
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| 67 | SILIBININ AND RELATED COMPOUNDS ARE DIRECT INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE | ||
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Summary: Henri Mondor, Université Paris 12, Créteil, France. Short Title: Silibinin is a direct inhibitor of HCV... | Madaus. R.-T. Pohl is an employee of Rottapharm | Madaus. Abbreviations: HCV: hepatitis C virus; IFN... ,version1-22Mar2010 #12;3 concentration 50%; HCVcc: infectious HCV particles; CC50: cytostatic |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 68 | Depla et al. -HCV-induced lipid droplet clustering Page 1 Cellular and Molecular Life Sciences -(2010) 67:31513161 | ||
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Summary: Depla et al. - HCV-induced lipid droplet clustering Page 1 Cellular and Molecular Life Sciences... in "Cell Mol Life Sci 67, 18 (2010) 3151-61" DOI : 10.1007/s00018-010-0373-z #12;Depla et al. - HCV... -induced lipid droplet clustering Page 2 Abstract Hepatitis C virus (HCV) release is linked to the formation |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 69 | Potential impact of vaccination on the hepatitis C virus epidemic in injection Judith A. Hahn a, | ||
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Summary: modeling Hepatitis C virus vaccine Background: Hepatitis C virus (HCV) causes significant morbidity... and mortality in injecting drug users (IDU) worldwide. HCV vaccine candidates have shown promise for reducing... efficacy and vaccine delivery strategies on the HCV epidemic in IDU has not been explored. Methods: We |
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Source: Getz, Wayne M. - Department of Environmental Science Policy and Management, University of California at Berkeley |
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Collection: Environmental Sciences and Ecology |
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| 70 | N d'ordre : ................ UNIVERSITE PARIS XII VAL DE MARNE | ||
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Summary: . .............................................................................................. 79 Figure 34. Localization of variant amino acids between HCV-3a-S and -NS infected patients... . ..................................................... 80 Figure 35. Phylogenetic analyses of the full-length HCV ORF from patients infected with ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 71 | Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate* | ||
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Summary: of the hepatitis C virus (HCV) envelope gly- coprotein E2 suggests an interaction of the viral enve- lope with cell... an important role in mediating HCV envelope-target cell interaction. Heparin and liver-derived highly sulfated... of HCV envelope requires E2-HSPG interaction. Docking of E2 to cellular HSPG may be the initial ... |
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Source: Linhardt, Robert J. - Center for Biotechnology and Interdisciplinary Studies & Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute |
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Collection: Biotechnology ; Chemistry |
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| 72 | Gondeau C 1 To the best of their knowledge, authors have no real or perceived conflicts of interests. | ||
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Summary: : patrick.maurel@inserm.fr Abstract Investigations on the biology of hepatitis C virus (HCV) have been... and robust cellular models of human origin able to support HCV replication and production in a reproducible... of antiviral molecules on different steps of HCV biology including virus entry, replication, particles |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 73 | This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. | ||
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Summary: polymorphisms in hepatocellular carcinoma: a differential impact according to seropositivity of HBV or HCV... in hepatocellular carcinoma: a differential impact according to seropositivity of HBV or HCV markers? I. Stücker1... ]. Hepatitis C virus (HCV) also appears to have contributed to the increasing incidence of HCC in North ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 74 | A Potent and Specific Morpholino Antisense Inhibitor of Hepatitis C Translation in Mice | ||
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Summary: Caffrey,1 Leonard Meuse,1 Mobin Karimi,1 Christopher H. Contag,2 and Mark A. Kay1 Hepatitis C virus (HCV... ) is an RNA virus infecting one in every 40 people worldwide. Current treatments are ineffective and HCV... control of HCV is a prime therapeutic target. We assessed the inhibitory potential of morpholino |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 75 | MOLECULAR THERAPY Vol. 5, No. 6, June 2002 Copyright The American Society of Gene Therapy | ||
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Summary: ) 498-6540. E-mail: Markay@stanford.edu. Hepatitis C virus (HCV) is an RNA virus infecting 1 in every 40... people worldwide. Development of new therapeutics for treating HCV has been hampered by the lack of small... to the cytoplasm of mouse liver cells in vivo. Transfected HCV genomic RNA failed to replicate in mouse liver |
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Source: Kay, Mark A. - Department of Genetics, Stanford University |
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Collection: Biology and Medicine |
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| 76 | The Global Spread of Hepatitis C Virus 1a and 1b: A Phylodynamic and Phylogeographic Analysis | ||
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Summary: virus (HCV) is estimated to affect 130180 million people worldwide. Although its origin is unknown... , patterns of viral diversity suggest that HCV genotype 1 probably originated from West Africa. Previous... suggested that epidemic HCV transmission began in 1900 and grew steadily until the late 1980s. However |
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Source: Shapiro, Beth - Department of Biology, Pennsylvania State University |
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Collection: Biology and Medicine |
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| 77 | AIDS . Author manuscript Ten-year incidence and risk factors of bone fractures in a cohort of treated | ||
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Summary: alcohol consumption and 3.6-fold (95 CI: 1.6 8.1) higher in those with Hepatitis C virus (HCV)% co... -infection. Specific monitoring of HCV/HIV-coinfected patients and active promotion of alcohol cessation should... glasses per day versus 19.5 ), were more frequently co-infected with HCV (48 versus 24.5 )% % % % and had |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 78 | NK cells in chronic hepatitis C and hepatitis B Fine Characterization of Intra-hepatic NK cells Expressing | ||
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Summary: Abstract Background/Aims. The fate of intrahepatic NK cell subsets in the course of HCV and HBV infections... ,h or CD158b,j receptors) from HCV or HBV patients were quantified by flow cytometry and localized... imbalance between CD56bright and CD56dim subsets were observed in chronic HCV patients as compared to HBV |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 79 | J Hepatol. Author manuscript Emerging role of hepatocellular carcinoma among liver-related causes of | ||
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Summary: : Dominique Salmon |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 80 | Investigating a New Generation of Ribozymes in Order to Michel V. Levesque, Dominique Levesque, Francis P. Brie`re, Jean-Pierre Perreault* | ||
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Summary: Investigating a New Generation of Ribozymes in Order to Target HCV Michel V. Le´vesque, Dominique... Virus (HCV) have been considered to possess high potential. Towards this end, ribozymes (i.e. RNA... of in order to develop an efficient and durable ribozyme-based technology with which to target HCV (+) RNA |
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Source: Perreault, Jean-Pierre - Département de biochimie, Université de Sherbrooke |
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Collection: Biology and Medicine |
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| 81 | JOURNAL OF VIROLOGY, June 2010, p. 62186228 Vol. 84, No. 12 0022-538X/10/$12.00 doi:10.1128/JVI.02271-09 | ||
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Summary: , United Kingdom4 Received 27 October 2009/Accepted 26 March 2010 Hepatitis C virus (HCV) replication... -resistant and immune escape variants. Here, we analyzed HCV populations during trans- mission and diversification... reads. To sample diversity, four locations in the HCV genome were analyzed, ranging from high diversity |
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Source: Bushman, Frederic - Department of Microbiology, University of Pennsylvania |
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Collection: Biology and Medicine |
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| 82 | Chemistry & Biology 13, 18, January 2006 2006 Elsevier Ltd All rights reserved DOI 10.1016/j.chembiol.2005.10.006 Peroxisome Proliferator-Activated Receptor a | ||
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Summary: 12 Oxford Street Cambridge, Massachusetts 02138 Summary Hepatitis C virus (HCV) is a global health... problem and a leading cause of liver disease. Here, we demonstrate that the replication of HCV replicon... no effect on HCV replica- tion in Huh-7 cells, whereas PPARa downregulation in- hibited HCV ... |
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Source: Xie, Xiaoliang Sunney - Department of Chemistry and Chemical Biology, Harvard University |
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Collection: Chemistry ; Biotechnology |
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| 83 | Lambotin M. et al. JVI00517-10 V2 Distinct Intracellular Trafficking of Hepatitis C Virus in Myeloid and5 | ||
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Summary: mechanisms of hepatitis C virus (HCV)3 antigen uptake and processing by blood DCs are poorly defined. Here we... show that human4 blood DC subsets acquire HCV independent of the classical HCV entry factors. Following... 5 HCV uptake, human plasmacytoid and myeloid DC subsets deliver HCV ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 84 | HIV-infected adults with CD4 cell count above 500/mm3 on long term combination | ||
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Summary: ), Action Coordonnée n°7 (AC7) ; Sidaction Ensemble contre le Sida and Laboratories: Abbott, Boehringer... group (injecting drug use versus others) and hepatitis C virus (HCV) co-infection as defined... by the presence of HCV antibody or plasma HCV-RNA at baseline, since similar types of analyses reported ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 85 | VALIDATION AND COMPARISON OF SIMPLE NON INVASIVE INDEXES FOR PREDICTING LIVER FIBROSIS IN HIV-HCV COINFECTED PATIENTS: ANRS CO3 | ||
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Summary: VALIDATION AND COMPARISON OF SIMPLE NON INVASIVE INDEXES FOR PREDICTING LIVER FIBROSIS IN HIV-HCV... fibrosis indexes in HIV-HCV coinfected patients *Composition of the GECSA (Aquitaine Cohort): Scientific... : Although an increasing number of non-invasive fibrosis markers is available in HCV monoinfected patients |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 86 | Hepatitis C Virus Internal Ribosome Entry Site-mediated Translation Is Stimulated by Specific Interaction of Independent | ||
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Summary: site (IRES) of hepatitis C virus (HCV) in vitro. Using a yeast three-hybrid sys- tem, we demonstrated... with HCV IRES in vivo. The exogenous addition of purified full-length and truncated La proteins in rabbit... reticulocyte lysate showed dose-dependent stimulation of HCV IRES-mediated translation. However, an addi- tive |
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Source: Srinivasan, N. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore |
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Collection: Biology and Medicine |
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| 87 | 1782 THE LANCET Vol 354 November 20, 1999 Background In chronic HIV-1 infection, dynamic equilibrium | ||
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Summary: in plasma HIV-1 RNA. To define HIV-1 and hepatitis C virus (HCV) dynamics, we used plasma apheresis... of whom were also co-infected with HCV. Rates of virion clearance were derived by non-linear least... ·0069/min (9·9/day; half-life 100182 min) for HCV. These values provided estimates of daily particle |
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|
Source: Bonhoeffer, Sebastian - Institut für Integrative Biologie, Eidgenössische Technische Hochschule Zürich (ETHZ) |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 88 | EXTRACTING RULE SCHEMAS FROM RULES, FOR AN INTELLIGENT LEARNING DATABASE SYSTEM | ||
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Summary: is based on three existing tools : KEShell12, dBASE3, and HCV10. These components are described in Section... for their efficient use. HCV is a low-order polynomial induction algorithm that generates rules suitable for use... in KEShell. However, the rules produced by HCV are not grouped according to schemas. This paper ... |
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|
Source: Sutcliffe, Geoff - Department of Computer Science, University of Miami |
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Collection: Computer Technologies and Information Sciences |
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| 89 | J Hepatol . Author manuscript The low-density lipoprotein receptor plays a role in the infection of primary | ||
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Summary: receptor (LDLR) in hepatitis C virus (HCV) infection of human hepatocyte has not been demonstrated. Normal... primary human hepatocytes infected by serum HCV were used to document this point. Methods Expression... or 25-hydroxycholesterol. Intracellular amounts of replicative and genomic HCV RNA strands used as end |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 90 | VIRAL HEPATITIS Expression of Paramyxovirus V Proteins Promotes | ||
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Summary: with laboratory strains of hepatitis C virus (HCV), although levels of virus replication vary significantly... clearance. To investigate possible contribu- tions of the interferon (IFN) system to control HCV infection... for visualization of HCV-infected cells. V protein-transduced HFLC supported enhanced (10 to 100-fold) levels ... |
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|
Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT) |
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Collection: Biotechnology ; Biology and Medicine |
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| 91 | JOURNAL OF VIROLOGY, July 2003, p. 78437855 Vol. 77, No. 14 0022-538X/03/$08.00 0 DOI: 10.1128/JVI.77.14.78437855.2003 | ||
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Summary: The nonstructural proteins of hepatitis C virus (HCV) have been shown previously to localize to the endoplasmic... reticulum (ER) when expressed singly or in the context of other HCV proteins. To determine whether... the expression of HCV nonstructural proteins alters ER function, we tested the effect of expression of NS2/3/4A |
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|
Source: Kirkegaard, Karla - Department of Microbiology and Immunology, Stanford University |
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Collection: Biology and Medicine |
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| 92 | Initiation of protein synthesis in eukaryotes requires the ordered assembly of ribosomal pre-initiation complexes, | ||
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Summary: IRES elements. Structural and biochemical studies of the IRES found in hepatitis C virus (HCV) have... discuss recent advances in understanding HCV IRES structure, function and interactions with translation... . Architecture of the HCV IRES The positive-strand RNA genome of the flavivirus HCV has been ... |
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Source: Doudna, Jennifer A. - Department of Molecular and Cell Biology, University of California at Berkeley |
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Collection: Biology and Medicine |
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| 93 | Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures | ||
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Summary: , 2009) Hepatitis C virus (HCV) remains a major public health problem, affecting approximately 130... million people worldwide. HCV infection can lead to cirrhosis, hepatocellular carcinoma, and end... and therapeutic options are severely limited; there is no HCV vaccine available, and nonspecific, IFN |
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|
Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT) |
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Collection: Biotechnology ; Biology and Medicine |
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| 94 | DOI: 10.1126/science.277.5325.574 , 574 (1997);277Science | ||
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Summary: . The Abbott HCV EIA 2.0 assay (Abbott Laboratories, Abbot Park, IL) con- tains three recombinant HCV antigens... Interagency Animal Model Committee. 17. Antibodies to HCV were measured by commercial enzyme immunoassays... : HC34, polyprotein amino acid residues 1 to 150 ... |
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|
Source: Murray, Andrew W. - Department of Molecular and Cellular Biology, Harvard University |
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Collection: Biology and Medicine |
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| 95 | DOI: 10.1126/science.277.5325.574 , 574 (1997);277Science | ||
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Summary: . The Abbott HCV EIA 2.0 assay (Abbott Laboratories, Abbot Park, IL) con- tains three recombinant HCV antigens... Interagency Animal Model Committee. 17. Antibodies to HCV were measured by commercial enzyme immunoassays... : HC34, polyprotein amino acid residues 1 to 150 ... |
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|
Source: Straight, Aaron - Department of Biochemistry, Stanford University |
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Collection: Biology and Medicine |
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| 96 | Downregulation of Gadd45 Beta Expression by Hepatitis C1 Virus Leads to Defective Cell Cycle Arrest2 | ||
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Summary: Running title: Downregulation of Gadd45 beta by HCV29 30 Key words: hepatocellular carcinoma, HCV, Gadd... including37 hepatocellular carcinomas. Chronic infection by hepatitis C virus (HCV) is a major38 risk factor... . Here, we demonstrate a novel link between40 diminished Gadd45 expression and HCV ... |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 97 | Universit Joseph Fourier-Grenoble 1 UFR de Biologie | ||
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Summary: Characterisation of Intrahepatic NK Cells Expressing Natural Killer Receptors in Chronic HCV and HBV Infections... Cell HBV/VHB: Hepatitis B virus HCV/VHC: Hepatitis C virus HLA-1/-2: Human Leukocyte Antigen type ½ IL... 'entre eux, le virus de l'hépatite C (HCV). tel-00610581,version1-22Jul2011 #12;8 Le virus de l'hépatite C |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 98 | Genetic variation in IL28B and spontaneous clearance of hepatitis C virus | ||
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Summary: . Goldstein3 & Mary Carrington2,13 Hepatitis C virus (HCV) infection is the most common blood- borne infection... in the United States, with estimates of 4 million HCV-infected individuals in the United States and 170 million... worldwide1 . Most (7080%) HCV infections persist and about 30% of individuals with persistent ... |
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|
Source: Kidd, Kenneth - Department of Genetics, Yale University |
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Collection: Biology and Medicine |
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| 99 | Methods Mol Biol . Author manuscript Polypyrrole-peptide microarray for biomolecular interaction analysis by | ||
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Summary: prism covered with a thin gold layer and an application example is given, dealing with the screening... of serums from patients infected with hepatitis C Virus (HCV) for their content in anti-HCV antibodies... % ° - C for a conservation longer than 2 weeks).° The chips consist in glass prisms coated with a ... |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 100 | The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule | ||
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Summary: Technologie de Saclay, Gif-sur-Yvette, France Abstract Hepatitis C virus (HCV), a major cause of chronic liver... .5 cells by infectious HCV particles (HCVcc) in a dose-dependent manner, suggesting that it adopts a native... bonds, which are strictly conserved across HCV genotypes. Furthermore, circular dichroism combined |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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