| Sample search results for: a-subunit isoforms enzyme |
| 1 | Nucleolar Proteome Database (http://www.lamondlab.com/NoPDB) August 2004 Acc # Acc # IPI Protein | ||
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Summary: 59344 HPBRII-4 mRNA Splicing related factor Q12874 IPI00029764 59154 Splicing factor 3A subunit 3... 23637 RNA modifying enzymes and related proteins P26599-1 IPI00179964 57357 Splice isoform 1 of P26599... modifying enzymes and related proteins P48729 IPI00183400 39118 Casein kinase I, ... |
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Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee |
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Collection: Biology and Medicine |
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| 2 | Nucleolar Proteome Database (http://www.lamondlab.com/NoPDB) August 2004 Acc # Acc # IPI Protein | ||
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Summary: /scleroderma autoantigen 2 RNA modifying enzymes and related proteins Q07244-1 IPI00216049 51230 Splice isoform 1 of Q07244... transcription factor 1 RNA polymerase Q12874 IPI00029764 59154 Splicing factor 3A subunit 3 Splicing related... 4 homolog RNA modifying enzymes and related ... |
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Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee |
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Collection: Biology and Medicine |
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| 3 | Melittin induces both time-dependent aggregation and inhibition of Na,K-ATPase from duck salt glands however these two processes | ||
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Summary: ,K-ATPase a-subunit as a result of enzyme aggregation (A) and loss of Na,K-ATPase activity (B) after... courses of melittin-induced loss of Na,K-ATPase a-subunit as a result of enzyme aggregation (A) and loss... at sequence MI(603)DPPRAT that is highly conserved for all isoforms of ... |
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Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 4 | ORIGINAL ARTICLE doi:10.1111/j.1558-5646.2008.00483.x | ||
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Summary: ORIGINAL ARTICLE doi:10.1111/j.1558-5646.2008.00483.x ENZYME ISOFORMS MAY INCREASE PHENOTYPIC... , Florida 32306 Received January 21, 2008 Accepted July 2, 2008 Enzyme isoforms are found in many cellular... , or in their reaction rates. The evolutionary significance of enzyme ... |
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Source: Bertram, Richard - Institute of Molecular Biophysics & Department of Mathematics, Florida State University; Houle, David - Department of Biological Science, Florida State University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology ; Mathematics |
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| 5 | Eur. J. Biochem. 267, 20712078 (2000) q FEBS 2000 Effect of streptozotocin-induced diabetes on rat liver Na1 | ||
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Summary: .W., Koster, J., Xie, Z.J. & Mercer, R.W. (1994) The a-subunit of the Na,K-ATPase has catalytic activity... and K1 -activated phosphatase reside on different a-subunits. J. Biol. Chem. 273, 28813±28821. 47... in membrane fluidity as typically this enzyme will increase in response to an enhancement of membrane fluidity |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 6 | Isolation of Six Putative P-typeATPase p SubunitPCR Fragmentsfrom the | ||
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Summary: been made in the identification of isoforms of P-type ATPase subunits. Of the P-type ATPases... characterized, only the four cx subunit isoforms of Na,K-ATPaselor the two a subunit isoforms of the closely... related enzyme H,K-ATPase2are known to associate with p subunits. To date, studies investigating |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 7 | Role of Alternative Splicing in Generating Isoform Diversity Among Plasma Membrane Calcium Pumps | ||
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Summary: Role of Alternative Splicing in Generating Isoform Diversity Among Plasma Membrane Calcium Pumps... Membrane Calcium Pump Isoforms 25 IV. Four Genes and Alternative Ribonucleic Acid Splicing Generate... a Multitude of Plasma Membrane Calcium Pump Isoforms 26 V. Alternative Splicing Options of Mammalian Plasma |
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Source: Zacharias, David A. - Whitney Laboratory for Marine Bioscience, University of Florida |
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Collection: Biology and Medicine |
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| 8 | Differential trafficking of carboxyl isoforms of Ca2+ (Slo1) potassium channels | ||
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Summary: Slo1 a-subunit. Fig. 5D shows immunoblots of anti-myc precipitates probed with antibodies for PP2A... CK2a0 O54833 41.216 8 24 PP2A-A subunit AAH52678 65.267 18 30 Tubulin, a1 AAH83344 50.120 15 28 c... Differential trafficking of carboxyl isoforms of Ca2+ -gated (Slo1) potassium channels Donghui Maa |
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Source: Li, Min - Department of Neuroscience, Johns Hopkins University |
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Collection: Biology and Medicine |
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| 9 | 371Fish Physiology and Biochemistry 17: 371376, 1997. 1997 Kluwer Academic Publishers. Printed in the Netherlands. | ||
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Summary: in the Netherlands. Expression of Na+ ,K+ -ATPase subunit isoforms in the European eel (Anguilla anguilla) C... , University of St Andrews, St Andrews, Fife KY16 9TS, Scotland, UK Keywords: Anguilla anguilla, 2 isoform, 3... isoform, brain, cDNA, eel, mRNA, Na+ ,K+ -ATPase, nucleotide sequence, PCR Abstract Reverse transcriptase |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 10 | Role of homologous ASP334 and GLU319 in human non-gastric H,K-and Na,K-ATPases in cardiac glycoside binding | ||
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Summary: in this group are the four isoforms (a1, a2, a3, and a4) of the a-subunit of Na,K-ATPase, the a-subunit... -Hess, Functional differences between a-subunit isoforms of the rat Na,K-ATPase expressed in Xenopus oocytes, J... of gastric proton pump or H,K-ATPase (aHKg) and the ... |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 11 | pubs.acs.org/BiochemistryPublished on Web 02/16/2010r 2010 American Chemical Society Biochemistry 2010, 49, 25932603 2593 | ||
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Summary: Isoform of Snow Flea Antifreeze Protein, Yee-Foong Mok,§ Feng-Hsu Lin,§ Laurie A. Graham,§ Yeliz Celik... larger. This AFP is hyperactive and comprises two isoforms [Graham, L. A., and Davies, P. L. (2005... ) Science 310, 461]. The larger isoform (15.7 kDa) exhibits several-fold higher activity than the smaller |
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Source: Braslavsky, Ido - Department of Physics and Astronomy, Ohio University |
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Collection: Physics ; Materials Science |
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| 12 | Light-Driven Translocation of the Protein Phosphatase 2A Complex Regulates Light/Dark Dephosphorylation of Phosducin and Rhodopsin | ||
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Summary: , a significant increase in the immunoreactive protein level of the A, C, and B56epsilon PP2A subunits is observed... preparation of purified PP2A subunits for antibody production, the fractions from the HTP column containing... phosphorylated phosducin was pooled for analysis on preparative SDS-PAGE to ... |
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Source: Southern California, University of - Mary D. Allen Laboratories for Vision Research |
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Collection: Biology and Medicine |
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| 13 | ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS Vol. 332, No. 1, August 1, pp. 4757, 1996 | ||
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Summary: . In higher plants, it is a ubiquitous cytosolic enzyme. those of the larger Mr PEPC isoforms: (i) the anti... . Detection of Other Enzymes in Purified PEPC Fractions The HMM isoforms were not homogeneous prepara- tions... in the enzyme's oligomeric Metabolic Regulation of the Different ... |
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Source: Plaxton, William - Department of Biology, Queen's University (Kingston) |
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Collection: Biology and Medicine |
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| 14 | Biochem. J. (2000) 351, 6777 (Printed in Great Britain) 67 Human 3-hydroxysteroid dehydrogenase isoforms (AKR1C1AKR1C4) of | ||
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Summary: dehydrogenase (3- HSD) isoforms of the aldo-keto reductase (AKR) superfamily. The enzymes correspond to type 1 3... catalysed by homogeneous recombinant human 3-HSD isoforms Enzyme Km (µM) Vmax (nmol/min per mg) kcat (min-1... reduction and 20-hydroxy- steroid oxidation catalysed by homogeneous recombinant ... |
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Source: Jez, Joseph - Department of Biology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 15 | Interaction of a Kinesin-like Protein with Calmodulin Isoforms from Arabidopsis* | ||
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Summary: to KCBP, we examined the CaM-dependent enzyme activity of bovine brain PDE using AtCaM isoforms... Interaction of a Kinesin-like Protein with Calmodulin Isoforms from Arabidopsis* (Received... and other plants there are multiple calmodulin isoforms. However, the role of these iso- forms in regulating |
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Source: Reddy, A.S.N - Department of Biology, Colorado State University |
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Collection: Biology and Medicine ; Biotechnology |
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| 16 | Neuron, Vol. 19, 185196, July, 1997, Copyright 1997 by Cell Press cAMP-Dependent Regulation of Cardiac L-Type Ca2 | ||
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Summary: - nase and facilitate phosphorylation reactions by localiz- channel 1C and 2a subunits and labeled... was that both the 1C and the 2a subunits were basally phosphor-campus neurons (Rosenmund et al., 1994... , an in- crease in phosphorylation of the 2a subunit was de- ... |
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Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle |
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Collection: Biology and Medicine |
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| 17 | Comparative Biochemistry and Physiology Part B 151152 (2002) 185200 1096-4959/02/$ -see front matter 2002 Elsevier Science Inc. All rights reserved. | ||
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Summary: systems. Phosphorylation of specific serine and threonine residues on the a- subunit by both protein... ) which are known to co-localise with the a-subunit have been implicated as potential regulators... . Increases in enzyme activity were apparent 3 h after the feeding event and peaked at 9 h before returning |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 18 | Identification of the Amino Terminus of Neuronal Ca2 Channel 1 Subunits 1B and 1E as an Essential Determinant | ||
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Summary: - cessory 2- and 2a subunits in Xenopus oocytes and mam- malian (COS-7) cells. The 1Elong showed biophysical... (rbEII) was expressed with 2- but without 2a subunits in Xenopus oocytes (together with D2 dopamine receptors). Left... subunits. 1Elong was expressed with both 2- and 2a ... |
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Source: Dolphin, Annette C. - Department of Neuroscience, Physiology and Pharmacology, University College London |
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Collection: Biology and Medicine |
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| 19 | Structural determinants of calcium channel subunit Hongyan Liu, Kevin f? Campbell | ||
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Summary: by a,, subunits,[42]which have several isoforms (see table II) and appear to be expressed in several... of the cardiac calcium channel a, subunit gene generates developmentally regulated isoforms in the heart. Proc... . Molecular cloning of multiple subtypes of a ... |
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Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa |
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Collection: Biology and Medicine |
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| 20 | Functional diversity among a family of human skeletal muscle myosin motors | ||
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Summary: muscle fibers correlate with the predominantly expressed MyHC isoform, but a functional analysis... of homogenous skeletal muscle myosin isoforms has not been possible. This is due to the difficulties... of separating the multiple isoforms usually coexpressed in muscle fibers, as well as the lack of an expression |
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Source: Spudich, James A. - Department of Biochemistry, Stanford University |
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Collection: Biology and Medicine |
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| 21 | Developmentally Regulated Switching of Titin Size Alters Myofibrillar Stiffness in the Perinatal Heart | ||
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Summary: and mechanics of cardiac-titin isoforms during perinatal rat heart development. Gel electrophoresis... and immunoblotting revealed a single, 3.7-MDa, N2BA isoform present 6 days before birth and an additional, also... previously unknown, N2BA isoform of 3.5 to 3.6 MDa expressed in the near-term fetus. These large ... |
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Source: Leake, Mark C. - Department of Physics, University of Oxford |
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Collection: Physics ; Biology and Medicine |
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| 22 | MOLECULAR AND CELLULAR BIOLOGY, Sept. 2003, p. 61296138 Vol. 23, No. 17 0270-7306/03/$08.00 0 DOI: 10.1128/MCB.23.17.61296138.2003 | ||
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Summary: . Molecular basis of competition between HSF2 and catalytic subunit for binding to the PR65/A subunit of PP2A... and phorbol esters (7), as well as the association of the phosphorylated histone isoform with immediate... activity among all human and yeast isoforms of PP2A (18), the regu- latory subunit is by ... |
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Source: Corces, Victor G. - Department of Biology, Emory University |
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Collection: Biology and Medicine |
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| 23 | ABBREVIATIONS: AcCh, acetylcholine; a-BgTx, a-bungarotoxin; SOS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; MBTA, 4-(N-maleimido)benzyltnmethylammonium iodide; Endo F, endoglycosidase F; EDTA, ethylenediaminetetraacetic acid; BSA, bov | ||
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Summary: of the lower molecular weight polypeptides and, at the highest enzyme concentration examined (a-subunit/V8, 5... enzyme concentration (a-subunit/V8, 15:1, w/w). The digestion pattern was not apparently modified... . MOLECULAR PHARMAcoLoGY, 29:649-656 Location of a Polypeptide Sequence within the ... |
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Source: Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University |
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Collection: Biology and Medicine |
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| 24 | Second Messengers cAMP is Produced by the Enzyme _________________ | ||
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Summary: Second Messengers cAMP is Produced by the Enzyme _________________ Its Production and Subsequent... _____________, Phosphoinositides, Inositol triphosphate (IP3), Diacyl Glycerol and Nitric Oxide Enzymes that Generate Second... Isoforms have Different ______________________ and can Bind Different ________________ Different ... |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 25 | Characterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTIN1 | ||
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Summary: Characterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTI´N1 , JAUME BOSCH1 , JORDI... -like activity. This isoform can be easily obtained by solid phase synthesis methods. Our objective in this study... phase synthesis was employed for the synthesis of the 5 kDa GH isoform. Circular dichroism and limited |
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Source: Pompeu Fabra, Universitat - Departament de Ciències Experimentals i de la Salut, Proteomics and Protein Chemistry Unit |
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Collection: Biotechnology |
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| 26 | 8 Photoreceptor Phosphodiesterase (PDE6) | ||
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Summary: G-protein, transducin. Following GDPGTP exchange on the a-subunit of transducin and [Ca2+] DK... exchange of GDP (gray circle) for GTP (red circle), and formation of the activated transducin a-subunit... on the a-subunit, which is not subject to regulation by calcium. Rather, the GTPase rate is modulated |
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Source: Cote, Rick H. - Department of Biochemistry and Molecular Biology, University of New Hampshire |
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Collection: Biology and Medicine |
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| 27 | The migrations of anadromous fish between freshwater and seawater represent remarkable transformations in the | ||
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Summary: , as exhibited by the samples collected at Whonnock, was characterised by a significant increase in 1a subunit m... in enzyme activity has been proposed as predictive of the entry date into seawater (Nielsen et al., 2004... isoforms in response to seawater transfer and speculated that ... |
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Source: Cooke, Steven J. - Department of Biology, Carleton University; Farrell, Anthony P. - Faculty of Land and Food Systems, University of British Columbia; Hinch, Scott G. - Forest Sciences Department, University of British Columbia |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 28 | Supplemental Data S1 mSin1 Is Necessary for Akt/PKB | ||
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Summary: Supplemental Data S1 mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three... with the same enzymes. The resulting plasmid was named pMSCV-TAP. pMSCV-TAP was then cut with Xho... and Expression of Human mSin1 Isoforms Human mSin1 isoforms were cloned by RT-PCR from mRNA iso- lated from ... |
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Source: Sabatini, David M. - Whitehead Institute for Biomedical Research & Department of Biology, Massachusetts Institute of Technology (MIT) |
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Collection: Biology and Medicine |
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| 29 | Structure/function analysis of Na -K -ATPase central isoform-specific region: involvement in PKC regulation | ||
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Summary: -type 1 is inhibited. Interestingly, the 2-isoform resembles the truncated enzyme in this respect. How... and others have established the influence of the NH2-terminal region on isoform-specific enzyme kinet- ics... Structure/function analysis of Na -K -ATPase central isoform-specific ... |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 30 | The Isoform-Specific Region of the Na,K-ATPase Catalytic Subunit: Role in Enzyme Kinetics and Regulation by Protein Kinase C | ||
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Summary: The Isoform-Specific Region of the Na,K-ATPase Catalytic Subunit: Role in Enzyme Kinetics... component of the enzyme, is a membrane-spanning protein expressed as four isoforms (R1, R2, R3, and R4... enzyme at the plasma membrane is limitated by the amount of isoforms ... |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 31 | Skeletal muscles exhibit considerable variability in their physiological properties, with muscle fiber type being coupled | ||
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Summary: al., 1972). More recently, specific myosin heavy chain (MHC) isoforms present in different muscles... , 2002). Although single fibers expressing multiple MHC isoforms have sometimes been interpreted as being... expressing more than one myosin heavy chain (MHC) isoform at the level of fiber proteins and/or m |
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Source: Medler, Scott - Department of Biological Sciences, State University of New York at Buffalo |
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Collection: Biology and Medicine |
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| 32 | A mathematical model for collagen fibre formation during foetal and adult dermal wound healing | ||
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Summary: isoforms of the regulatory chemical transforming growth factor /3.Numerical simulations of the model lead... in adult wound healing. We investigate the effect of topical application of TGFP isoforms during healing... inactive (latent forms of TGFP isoforms are secreted by many cells (Martin et al. 1992 ; Streuli et al |
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Source: Maini, Philip K. - Centre for Mathematical Biology & Mathematical Institute, University of Oxford; Sherratt, Jonathan A. - Department of Mathematics, Heriot-Watt University |
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Collection: Biology and Medicine ; Mathematics |
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| 33 | 2 0 0 3 B J U I N T E R N A T I O N A L | 9 2 , 7 9 3 8 0 2 | doi:10.1046/j.1464-410X.2003.04460.x 7 9 3 Original Article | ||
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Summary: and biogenesis of the enzyme complex [6]. The b1 isoform is ubiquitously expressed, whereas the b2 and b3... isoforms also have an effect on the biogenesis of the enzyme complex, and on the abundance and longevity... .04460.x 7 9 3 Original Article NA,K-ATPASE ISOFORMS IN RAT VENTRAL ... |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 34 | Dynamics of Na Cotransporter | ||
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Summary: for a cytosolic epitope, and reacts with all isoforms of the a- subunit of distant species. It was developed by D... M, Yu M, Hwang P. 1998. Isoform expression of the Naþ ,Kþ -ATPase a-subunit in gills of the teleost... . The abundance of NKA a-subunit protein also ... |
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Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 35 | doi:10.1152/ajprenal.00089.2007 294:859-866, 2008. First published Dec 19, 2007;Am J Physiol Renal Physiol | ||
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Summary: -K-ATPase -isoform diversity also plays a role in the ability of the enzyme to relay ouabain-induced signaling... Physiology onMay23,2008ajprenal.physiology.orgDownloadedfrom #12;Isoform specificity of Na... Pierre SV, Sottejeau Y, Gourbeau J-M, Sa´nchez G, Shidyak A, Blanco G. Isoform specificity of Na |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 36 | Evaluation of the role of AMP-activated protein kinase and its downstream targets in mammalian hibernation | ||
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Summary: cells (Salt et al., 1998). Also, the specificity of the a-subunit isoforms towards peptide substrates... in the activation loop of the a-subunits (Hawley et al., 1996) and phosphorylation at this site is both sufficient... polyclonal antibodies were from Santa Cruz. Anti-phospho Thr172 human AMPK a- ... |
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Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 37 | Plant biotin-containing carboxylasesq Basil J. Nikolau,a,* John B. Ohlrogge,b | ||
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Summary: of the fact that in most plants the plastidic isoform of ACCase is a heteromeric enzyme that is un- stable due... of the MCC-A and MCC-B subunits established that the MCC-A subunit contains BC and BCC functional domains... by the posttransla- tional biotinylation of the MCC-A ... |
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Source: Wurtele, Eve Syrkin - Department of Genetics, Development and Cell Biology, Iowa State University |
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Collection: Biotechnology ; Renewable Energy |
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| 38 | Anne BENZINGER et al www.cell-research.com | Cell Research, 15(4):219-227, Apr 2005 | ||
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Summary: The crystal structure of the non-liganded 14-3-3 protein: insights into determinants of isoform specific... -3-3 isoform, a transcriptional target of p53, exerts its inhibitory effect on the cell cycle in the presence... of other 14-3-3 isoforms, which are constitutively expressed at high levels. In order to identify |
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Source: Hermeking, Heiko - Max-Planck-Institut für Biochemie |
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Collection: Biology and Medicine |
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| 39 | F-type and V-type reversible ATPases are membrane-associated molecular machines | ||
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Summary: ,21 . The ion- translocating, membrane-spanning F0 sector is a complex of the integral-membrane a-subunit, two b... -bound c-subunits5,2225 .The c-ring (rotor) is thought to slide along its interface with the a-subunit... V-type ATPases have one or two peripheral stalks15 . In addition to the large a-subunit and the c |
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Source: Steinhoff, Heinz-Jürgen - Fachbereich Physik, Universität Osnabrück |
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Collection: Biology and Medicine ; Physics |
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| 40 | Ligand Binding and Phagocytosis by CD16 (Fc Receptor III) Isoforms | ||
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Summary: by the cytoplasmic domain of Fc Rs, the phagocytosis of EA by CHO cells stably trans- fected with CD16A and CD16A-subunit... . The phagocytosis mediated by the CD16A-subunit chimeras expressed on CHO cells described in this report provides... Ligand Binding and Phagocytosis by CD16 (Fc Receptor III) Isoforms PHAGOCYTIC SIGNALING |
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Source: Zhu, Cheng - Department of Biomedical Engineering, Georgia Institute of Technology and Emory University |
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Collection: Engineering ; Biology and Medicine |
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| 41 | 10.1261/rna.1611309Access the most recent version at doi: published online July 27, 2009RNA | ||
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Summary: Zhou, Benjamin Czech, Julius Brennecke, et al. Loquacious isoform endo-siRNAs depends on a specific... .cshlp.orgDownloaded from #12;Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform RUI ZHOU,1... isoform, Loqs-PD, which is distinct from the one, Loqs-PB, required for the production of micro |
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Source: Higgins, Darren - Department of Microbiology and Molecular Genetics, Harvard University |
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Collection: Biology and Medicine |
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| 42 | Localization of Na,K-ATPase / Isoforms in Rat Sciatic Nerves: Effect of Diabetes and Fish Oil Treatment | ||
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Summary: Localization of Na,K-ATPase / Isoforms in Rat Sciatic Nerves: Effect of Diabetes and Fish Oil... ,K-ATPase isoforms. Some of these changes could be prevented by fish oil therapy. The aim of this study... ,K-ATPase-- Isoforms--Immunocytochemistry--Confocal laser scan- ning microscopy--Image analysis--Diabetes--Dietary fish |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 43 | Different Anesthetic Sensitivities of Skeletal and Cardiac Isoforms of the Brad S. Karon, Joseph M. Autry, Yongli Shi, Christine E. Garnett,| Giuseppe Inesi,| Larry R. Jones, | ||
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Summary: ) or (b) activate the SERCA 1 isoform. The finding that anesthetic interaction with enzyme isoforms... that halothane interacts directly with the SERCA 2a isoforms of the Ca- ATPase to inhibit the enzyme. Inhibition... Different Anesthetic Sensitivities of Skeletal and Cardiac ... |
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Source: Thomas, David D. - Departments of Biochemistry, Molecular Biology, & Biophysics, University of Minnesota |
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Collection: Biology and Medicine |
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| 44 | Alternatively spliced isoforms of the human constitutive androstane receptor | ||
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Summary: Alternatively spliced isoforms of the human constitutive androstane receptor Scott S. Auerbach... of genes encoding xenobiotic- and steroid- metabolizing enzymes. Regulatory processes that are mediated... protein isoform, exhibit compromised activities with respect to DNA binding, transcriptional activation |
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Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
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Collection: Biology and Medicine |
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| 45 | Hypertrophy of colonic smooth muscle: contractile proteins, shortening velocity, and regulation | ||
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Summary: in the contractile protein isoform composition. 1) There is a higher actin concentration in megacolon, primarily... caused by a larger proportion of y-isoforms. 2) There was no difference in myosin concentration or in SMl... isoforms and the lack of a simple relationship between myosin light chain phosphorylation and V, point |
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Source: Trinkle-Mulcahy, Laura - Department of Cellular and Molecular Medicine, University of Ottawa |
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Collection: Biology and Medicine |
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| 46 | The cGMP Signaling Pathway in Retinal Photoreceptors and the Central Role of | ||
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Summary: that are farnesylated (a-subunit) or geranylgeranylated (~-subunit). The enzyme-active site is denoted by the notch... diphosphate (GDP) for guanosine triphosphate (GTP), and formation of the activated transducin a-subunit... ]. This interaction catalyzes the exchange of bound GDP for GTP on the transducin ... |
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Source: Cote, Rick H. - Department of Biochemistry and Molecular Biology, University of New Hampshire |
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Collection: Biology and Medicine |
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| 47 | THE JUNCTIONAL SARCOPLASMIC RETICULUM PROTEIN JP-45 AFFECTS THE FUNCTIONAL EXPRESSION OF THE VOLTAGE DEPENDENT CALCIUM CHANNEL | ||
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Summary: defined (Catterall, 1995; Snutch and Reiner, 1992, Tsien et al., 1991). The ß1a subunit associates tightly... ) (Pragnell et al., 1994). The ß1a-subunit is important for plasma membrane expression of the 1.1 subunit... -terminal domains of 1.1 subunit as well as with the ß1a subunit. In ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 48 | Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4 and 6 in distinct membrane microdomains | ||
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Summary: Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4 and 6 in distinct... 115 Memphis, TN 38163 (901) 448-1181 rostrom@uthsc.edu Running title: Adenylyl cyclase isoforms... activity and increase airway diameter. We assessed expression of AC isoforms in human bronchial smooth |
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Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center |
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Collection: Biology and Medicine |
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| 49 | The Phosphorylation State of Translation Initiation Factors Is Regulated Developmentally and following Heat Shock in Wheat* | ||
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Summary: isoforms, whereas a lower level of the enzyme resulted in a partial conversion of the basic cluster... % the level of the basic form. The acidic and basic isoforms correspond well with the monophosphorylated (pI 5... to be modified by phosphorylation (31). The nonphosphorylated and phosphorylated isoforms ... |
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Source: Tullos, Desiree - Department of Biological and Ecological Engineering, Oregon State University |
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Collection: Environmental Sciences and Ecology |
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| 50 | Protein phosphorylation is recognized as a widespread and highly versatile regulatory mechanism that controls | ||
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Summary: from one gene3 . Note that the B class of PP2A subunits includes B, B, B and B (see main text... by binding the B55 and B56 subunits49 . In S. cerevisiae, PP2A subunits display dynamic localization patterns... that certain Ser/Thr- specific enzymes can dephosphorylate Tyr, and that many ... |
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Source: Trinkle-Mulcahy, Laura - Department of Cellular and Molecular Medicine, University of Ottawa |
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Collection: Biology and Medicine |
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| 51 | Separate Na,K-ATPase genes are required for otolith formation and semicircular canal development in zebrafish | ||
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Summary: and indicate that different isoforms play distinct functional roles in formation of inner ear structures. Our... RNA rescue Introduction Na,K-ATPase, also known as the sodium pump, is a key enzyme essential for maintaining... solutes and water across epithelia (Thomas, 1972). The active enzyme is a major consumer of ATP |
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Source: Dickman, J. David - Department of Anatomy and Neurobiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 52 | Associate editor: Neve Sensitization of adenylate cyclase by Gai/o-coupled receptorsB | ||
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Summary: as a locus for the expression of the sensitized adenylate cyclase response, and to isoform... abuse; Adenylate cyclase Abbreviations: AC19, adenylate cyclase isoforms 1 through 9; AGS, activator... .2. Multiple adenylate cyclase isoforms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 1 |
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Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University |
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Collection: Biology and Medicine |
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| 53 | Molecular and Biochemical Parasitology 99 (1999) 167181 Characterization of protein Ser/Thr phosphatases of the malaria | ||
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Summary: enzymes preferred to dephosphorylate the a-subunit of phosphorylase kinase to the b-subunit (Fig. 2... - rylase kinase by PfPP2A (, b-subunit; , a-subunit) and PfPP2B ( , b-subunit; , a-subunit) was carried... cytosolic extracts of the erythrocytic stage of the malaria parasite, Plasmodium falciparum. Both ... |
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Source: Fairlamb, Alan - Division of Biological Chemistry and Molecular Microbiology, University of Dundee |
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Collection: Biology and Medicine |
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| 54 | J Cell Sci. Author manuscript The junctional SR protein JP-45 affects the functional expression of the | ||
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Summary: defined ( ; , Catterall, 1995 Snutch and Reiner, 1992 Tsien et al., ). The 1a subunit associates tightly... (AID) ( ). The 1a-subunit is important for plasma membrane expression of the 1.1 subunit whereas a... directly with the I II loop, the COOH-terminal domains of 1.1 subunit as well as with the 1a ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 55 | BIOCHEMICAL ADAPTATION KENNETH B. STOREY | ||
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Summary: .5 of the enzyme to a value that closely matches in vivo F6P concentrations (0.16 mM) in working muscle. ISOFORM... enzyme/protein form, and in many cases, isozymes/isoforms have evolved that may differ in kinetic... isoforms, a wide variety of specialized needs and organ- specific ... |
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Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 56 | BIOCHEMICAL ADAPTATION KENNETH B. STOREY | ||
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Summary: on an enzyme or pro- tein cannot always be met by a single enzyme/protein form, and in many cases, isozymes/isoforms... proteins (e.g., enzymes, transporter proteins), and the integrated functioning of the biochemical reactions... and catalysis in enzymes. A decrease in temperature ... |
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Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 57 | C-Terminal Cleavage of Np63 Is Associated with TSA-Induced Apoptosis in Immortalized Corneal | ||
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Summary: Gene-specific primers for each isoform, including restriction enzyme sites, are listed in Table 1. A 50... desquamation, suggesting a potential role for Np63 isoforms in mediating surface cell apoptotic shedding... . In this study, the authors investigated a role for Np63 isoforms in caspase-mediated ... |
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Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development |
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Collection: Biology and Medicine |
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| 58 | Structure of the Rat Inhibin and Activin A-Subunit Gene and Regulation in an Ovarian Granulosa Cell Line* | ||
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Summary: both the 5 and 3 ends of the rat A-subunit cDNA clone rINB-5 (8). A combination of restric- tion enzyme... Structure of the Rat Inhibin and Activin A-Subunit Gene and Regulation in an Ovarian Granulosa Cell... the rat inhibin and activin A-subunit gene, which is composed of three exons, and have characterized ... |
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Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University |
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Collection: Biology and Medicine |
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| 59 | FRET evidence that an isoform of caspase-7 binds but does not cleave its substrate | ||
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Summary: FRET evidence that an isoform of caspase-7 binds but does not cleave its substrate Isaac T.S. Li a... Fluorescent resonance energy transfer (FRET) Enzyme kinetics a b s t r a c t A caspase-7 biosensor (v... decrease of 61%. In contrast, an isoform with the 23 N- terminal residues truncated (24casp7) bound to v |
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Source: |
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Collection: Biotechnology ; Engineering |
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| 60 | Binding assays of inhibitors towards selected V-ATPase domains F. Fernandesa | ||
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Summary: -subunits from enzymes of different origins. A possible explanation would be the participation of the a-subunit... (part of the enzyme membrane bound domain--V0) (Fig. 1A) in the inhibitory mechanism, since the isoform... to bind to these as strongly as to the entire V0 domain, apparently excluding a ... |
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Source: Hemminga, Marcus A. - Department of Molecular Physics, Wageningen Universiteit |
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Collection: Physics ; Biology and Medicine |
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| 61 | -Subunit of cardiac Na -K -ATPase dictates the concentration of the functional enzyme in caveolae | ||
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Summary: in cardiac myocytes. J Biol Chem 271: 10372 10378, 1996. 31. Periyasamy SM, Huang WH, and Askari A. Subunit... -Subunit of cardiac Na -K -ATPase dictates the concentration of the functional enzyme in caveolae... of the functional enzyme in caveo- lae. Am J Physiol Cell Physiol 291: C569C578, 2006. First ... |
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|
Source: Askari, Amir - Department of Biochemistry & Cancer Biology, University of Toledo; Askari, Amir - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 62 | doi:10.1152/ajpcell.00158.2007 293:1489-1497, 2007. First published Aug 29, 2007;Am J Physiol Cell Physiol | ||
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Summary: Physiol 287: H2173 H2182, 2004. 30. Liu L, Askari A. -Subunit of cardiac Na -K -ATPase dictates... the plasma membranes of most mammalian cells, and this pumping function of the enzyme is specifically... and assayed for the 1-subunit of Na -K -ATPase, since this isoform is pre- dominant in cardiac myocytes |
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Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 63 | Functional Interactions between Heterologously Expressed Starch-Branching Enzymes of Maize and the Glycogen | ||
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Summary: SBE isoforms of maize (Zea mays) away from the other plant enzymes involved in starch biosynthesis... typically requires a single isoform of the glucan synthase and branching enzyme activities. Starch... of these enzymes. In maize (Zea mays), there are at least five SS ... |
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Source: Scott, Paul - Department of Agronomy, Iowa State University |
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Collection: Biotechnology |
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| 64 | BIOINFORMATICS Vol. 19 Suppl. 1 2003, pages i118i121 DOI: 10.1093/bioinformatics/btg1015 | ||
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Summary: recently shown that a third of reliably-inferred alternative mRNA isoforms are candidates for nonsense... a single genetic locus to generate multiple mRNA isoforms, and it affects over a third (Brett et al., 2000... of alternative isoforms. Using the human genome sequence, databases of expressed sequence tags (ESTs |
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|
Source: Brenner, Steven E. - Department of Plant and Microbial Biology, University of California at Berkeley |
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Collection: Biotechnology |
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| 65 | Exploring Uncoupling Proteins and Antioxidant Mechanisms under Acute Cold Exposure in Brains of Fish | ||
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Summary: activates the expression of antioxidant enzymes, including SOD and GPx [33]. To date, three PPAR isoforms... (GLUTs) Western blot analysis with antibodies against the fish HIF-1a subunit demonstrates... (Lepomis cyanellus) demonstrates elevated activities of glycolytic enzymes, such as ... |
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|
Source: Academia Sinica, Institute of Atomic and Molecular Sciences, High-Field Physics and Ultrafast Technology Laboratory |
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Collection: Physics |
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| 66 | Transport and Pharmacological Properties of Nine Different Human Na,K-ATPase Isozymes* | ||
|
Summary: significantly differed depending on the but not on the isoform present in the enzyme complex (Table I... and isoforms, were expressed in Xe- nopus oocytes and were analyzed for their transport and pharmacological... are functional but differ in their turn- over rates depending on the isoform. On the other ... |
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|
Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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Collection: Biology and Medicine |
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| 67 | Coefficients for Active Transport and Thermogenesis of Ca2 Signe Kjelstrup,* Daniel Barragan, and Dick Bedeaux | ||
|
Summary: manner different performances of the enzyme isoforms. Four enzyme isoforms are examined, namely from... for this enzyme, in addition to the role played by the uncoupling protein. The existing isoforms may not have... Coefficients for Active Transport and Thermogenesis ... |
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|
Source: Kjelstrup, Signe - Department of Chemistry, Norwegian University of Science and Technology |
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Collection: Chemistry |
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| 68 | 2007LANDESBIOSCIENCE.DONOTDISTRIBUTE. [Cancer Biology & Therapy 6:10, 1-5, EPUB Ahead of Print: http://www.landesbioscience.com/journals/cbt/article/4787; October 2007]; 2007 Landes Bioscience | ||
|
Summary: Research Paper Novel Splice Isoforms of STRAD Differentially Affect LKB1 Activity, Complex Assembly... to differentiate in vitro. We report herein the discovery of several novel splice isoforms of STRAD... associates with the chromatin remodeling enzyme Brg1 and mediates progres- sion of cells through the G1 phase |
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|
Source: Marignani, Paola - Department of Biochemistry and Molecular Biology, Dalhousie University |
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Collection: Biology and Medicine |
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| 69 | Isoform-specific 3'-untranslatedSequences Sort a-cardiac and/3-cytoplasmic ActinMessenger | ||
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Summary: Isoform-specific 3'-untranslatedSequences Sort a-cardiac and/3-cytoplasmic ActinMessenger RNAs... . We demonstrate that in differentiating myo- blasts, the mRNAs encoding two actin isoforms... specific for each isoform. To address the mechanism of isoform-specific mRNA localization, molecular |
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|
Source: Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University |
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Collection: Biology and Medicine |
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| 70 | Bradfield; Mechanisms of Liver Carcinogenesis 10 UNIT III: Metabolism and Modifiers of Chemical Carcinogenesis | ||
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Summary: group of Phase II enzymes has coevolved. Phase II enzymes are best described as conjugating... or "synthetic" enzymes. They are classified by the fact that they conjugate large molecules onto chemical... substrates. The reason they are called Phase II arises from the observation that these enzymes usually ... |
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|
Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 71 | Unique Profile of Chicken Adiponectin, a Predominantly Heavy Molecular Weight Multimer, | ||
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Summary: , circulates as heavy, medium, and light molecular weight isoforms in mammals. Plasma heavy molecular weight... (HMW) adiponectin isoform levels are inversely correlated with the incidence of type 2 diabetes... conditions, adiponectin in chicken plasma, and adipose tissue is predominantly a multimeric HMW isoform |
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|
Source: Ramachandran, Ramesh - Department of Veterinary and Biomedical Sciences, Pennsylvania State University |
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Collection: Biology and Medicine |
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| 72 | INTRODUCTION Hundreds of protein kinases and protein phosphatases are | ||
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Summary: cellular events, including division, signalling, differentiation and metabolism. These enzymes... for proteins that bring the enzyme in proximity to the substrate. These proteins have been termed `targeting... isoforms (, / and 1), each encoded by distinct genes, in the mammalian cell (Sasaki et al., 1990; Barker et |
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|
Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee |
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Collection: Biology and Medicine |
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| 73 | The l l0-kD Spindle Pole Body Component of SaccharomycescerevisiaeIs a Phosphoprotein That Is Modified in a Cell Cycle-dependent Manner | ||
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Summary: body (SPB). Asynchronous wild-type cultures con- tain two electrophoretically distinct isoforms... isoforms in- corporate 32pi in vivo, suggesting that Spcll0p is post- translationally modified... by phosphorylation. The slower-migrating 120-kD Spcll0p isoform is converted to the faster-migrating ll2-kD ... |
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|
Source: Davis, Trisha N. - Department of Biochemistry, University of Washington at Seattle |
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Collection: Biology and Medicine ; Environmental Management and Restoration Technologies |
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| 74 | BioMed Central Page 1 of 14 | ||
|
Summary: the relation- ships of the enzymes found in other eukaryotes, particu- larly to determine if isoforms found... by two invariant Cys pairs in all known APRs [6]. However, a novel isoform of the enzyme from the moss... of host origin. The many distinct isoforms of the three ... |
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|
Source: Durnford, Dion G. - Biology Department, University of New Brunswick |
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Collection: Biology and Medicine |
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| 75 | Identification of Three Subunits of the High Affinity -Conotoxin MVIIC-sensitive Ca2 | ||
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Summary: products (1, 12, 22, 23). Since the activity of 1A subunits expressed in Xenopus oocytes can be blocked... (45 pM) was used to specifically label the high affinity -CTX MVIIC receptor. Polyclonal 1A subunit... little homology with the 1a subunit of skeletal muscle ... |
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|
Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa |
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Collection: Biology and Medicine |
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| 76 | J Physiol 577.1 (2006) pp 339352 339 Fibre type-specific increase in passive muscle tension | ||
|
Summary: , elevated PT was found in cells expressing fast myosin heavy chain (MyHC) isoforms, especially My... -linking status and isoform composition, and the titin isoform expression pattern are believed to be the major... ; Prado et al. 2005). Titin isoform size and stiffness are highly variable among fast-twitch ... |
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|
Source: Linke, Wolfgang A. - Fachbereichs Biologie, Westfälische Wilhelms-Universität Münster |
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Collection: Biology and Medicine |
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| 77 | -ATPase as a signal transducer Zijian Xie and Amir Askari | ||
|
Summary: , 429437. 24. Huang, L., Kometiani, P. & Xie, Z. (1997) Differential regulation of Na/K-ATPase a-subunit... and expression of various genes, only in recent years the mechanisms through which this plasma membrane enzyme... to establish that this enzyme is indeed the molecular machine that uses the energy of hydrolysis of ATP |
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|
Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo |
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|
Collection: Biology and Medicine |
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| 78 | ORIGINAL PAPER Lifetime-and caste-specific changes in flight metabolic rate | ||
|
Summary: in troponin T isoforms and increases in flight muscle maximal activities (Vmax) of the enzymes citrate... in the in vitro Vmax of these flight muscle metabolic enzymes. Estimates of in vivo flux (v) compared to maximum... flux of each enzyme in vitro (fractional velocity, v/Vmax) suggest that most ... |
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|
Source: Dukas, Reuven - Department of Psychology, McMaster University |
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|
Collection: Environmental Sciences and Ecology |
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| 79 | r XXXX American Chemical Society A dx.doi.org/10.1021/jm101007q |J. Med. Chem. XXXX, XXX, 000000 pubs.acs.org/jmc | ||
|
Summary: enzyme that may exist in ve isoforms (hLDH1-5), mostly located in the cytosol. There are only two types... .19 An ampli ed expression of this gene, measured as LDH-A subunit increased production, was found... as a tractable anticancer strategy. The X-ray crystal structure of the LDH-A ... |
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|
Source: Hergenrother, Paul J. - Department of Chemistry, University of Illinois at Urbana-Champaign |
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|
Collection: Chemistry |
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| 80 | Skeletal muscles differ significantly in their contractile properties, largely because of differences in myofibrillar | ||
|
Summary: of differences in myofibrillar protein isoforms among various fibers (Schiaffino and Reggiani, 1996). Crustacean... isoforms present in a particular fiber (Mykles, 1985a,b, 1988, 1997). Through these methods, crustacean... activity (Oganowski and Lang, 1979; Silverman et al., 1987) and a number of distinct myofibrillar isoforms |
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|
Source: Medler, Scott - Department of Biological Sciences, State University of New York at Buffalo |
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Collection: Biology and Medicine |
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| 81 | THEJOURNALOF BIOLOGICAL CHEMISTRY 0 1988by The American Society for Biochemistry and MolecularBiology, Inc. | ||
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Summary: Regulation of Tropoelastin Isoforms* (Receivedfor publication, September 29, 1987) William C. Parks... The production of tropoelastin isoforms was exam- ined by cell-free translation of nuchal ligament RNA from cows... isoform patterns were detected at different devel- opmental periods. 1) The fetal period was character |
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|
Source: Mecham, Robert - Center for Cardiovascular Research & Department of Cell Biology and Physiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 82 | Molecular and Cellular Endocrinology 171 (2001) 137149 Structure-function aspects and inhibitor design of type 5 | ||
|
Summary: -HSD). This enzyme shares 69% sequence identity with AKR1C3 and serves as a good model for this human isoform. AKR1C9... ) superfamily; it is formally AKR1C3. In vitro the homogeneous recombinant enzyme expressed in Escherichia coli... -hydroxysteroid oxidase. The enzyme will reduce 5a-DHT, D4 ... |
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|
Source: Jez, Joseph - Department of Biology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 83 | Marcella Martignoni1, Ruben de Kanter2 and Geny Groothuis3 1 Preclinical Development, Nerviano Medical Sciences, Viale Pasteur 10, 20014 Nerviano (MI), | ||
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Summary: , it is important to realize that humans differ from animals in isoform composition, expression and catalytic... activities of enzymes involved in drug metabolism. In fact, even small changes in the amino acid sequences... of these enzymes can give rise to profound differences in substrate specificity and catalytic activity. ... |
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|
Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 84 | Research report The circadian clock-containing photoreceptor cells in Xenopus laevis | ||
|
Summary: several isoforms of casein kinase I Cara M. Constancea,c,1 , Jin-Yuan Fanb,1 , Fabian Preussb , Carla B... for the analysis of retinal circadian rhythms. In this paper, several isoforms of X. laevis casein kinase I (CKI... variants of CKIy (a full-length form and deletion isoform, which is missing an exon that encodes a putative |
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|
Source: Phillips, Kimberley A. - Department of Biology, Hiram College |
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Collection: Biology and Medicine |
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| 85 | J Comp Physiol B DOI 10.1007/s00360-011-0600-4 | ||
|
Summary: ) at the Uni- versity of British Columbia--Okanagan (Kelowna, BC, Canada). The 1a subunit sequence showed 100... % sequence similarity to the O. mykiss NKA 1a subunit (GenBank Accession No. NM_001124461.1). The 1b subunit... . Accompanying the move- ment from seawater to freshwater was a signiWcant increase in ... |
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|
Source: Farrell, Anthony P. - Faculty of Land and Food Systems, University of British Columbia; Hinch, Scott G. - Forest Sciences Department, University of British Columbia |
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|
Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 86 | Annu. Rev. Physiol. 2001. 63:87194 Copyright c 2001 by Annual Reviews. All rights reserved | ||
|
Summary: , mutations, resurgent current s Abstract A variety of isoforms of mammalian voltage-gated sodium channels... of those isoforms have been functionally expressed in exogenous sys- tems. The subunit is associated... . The subunit isoforms have distinct patterns of development and localization in the nervous system, skeletal |
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|
Source: Goldin, Alan L. - Department of Microbiology and Molecular Genetics, University of California, Irvine |
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Collection: Biology and Medicine |
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| 87 | Biochem. J. (1999) 343, 443452 (Printed in Great Britain) 443 Mechanism of A-kinase-anchoring protein 79 (AKAP79) and protein | ||
|
Summary: 79 also associates with conventional, novel and atypical isoforms of PKC in itro and in i o... . Recently, targeting of these signalling enzymes to precise subcellular locations has emerged as a mechanism... three signalling enzymes to postsynaptic sites and has been proposed to function as a signalling |
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|
Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle |
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Collection: Biology and Medicine |
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| 88 | Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A | ||
|
Summary: -cytoplasmic domain cDNAs into pMAL vector disrupts expression of b-galactosidase a-subunit located at the downstream... to the PP2A- Ar-a isoform from CAD-NET cells, but none from parental CAD cells. In order to verify... /f, and one of e iso- forms from CAD-NET cells. In contrast, we recovered only one peptide from g isoform ... |
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|
Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 89 | *Corresponding Author: Steven E. Brenner--Department of Molecular and Cell Biology, University of California, Berkeley. Email: brenner@compbio.berkeley.edu | ||
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Summary: + isoform occurs when polyamine levels are low--a condition where the enzyme is not needed. Upon depletion... in humans result in mRNA isoforms thatharboraprematureterminationcodon... (PTC).Thesetranscriptsarepredictedtobedegraded by the nonsensemediated mRNA decay (NMD) pathway. One explanation for the abundance of PTCcontaining ... |
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|
Source: Brenner, Steven E. - Department of Plant and Microbial Biology, University of California at Berkeley |
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|
Collection: Biotechnology |
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| 90 | Expression of a duplicate Na,K-ATPase 1-isoform in the European eel (Anguilla anguilla) | ||
|
Summary: - and -isoform combinations have been shown to produce active enzymes with the ion specific- ity determined... suggest that the 233-isoform is an integral component of the Na,K-ATPase enzyme that is expressed... Expression of a duplicate Na,K-ATPase 1-isoform in the European eel (Anguilla ... |
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|
Source: Cutler, Chris - Department of Biology, Georgia Southern University |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 91 | Vacuolar and Plasma Membrane Proton-Adenosinetriphosphatases | ||
|
Summary: and Function of Vacuolar Proton-Adenosinetriphosphatases 363 A. Subunits definition and mechanism of action 363... evolution. II. SUBUNIT STRUCTURE AND FUNCTION OF VACUOLAR PROTON- ADENOSINETRIPHOSPHATASES A. Subunits... but are not part of the final complex. 2. Catalytic subunits A) ... |
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|
Source: Nelson, Nathan - Department of Biochemistry, Technion, Israel Institute of Technology |
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Collection: Biology and Medicine |
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| 92 | Gene Flow in the Face of Countervailing Selection: Adaptation to High-Altitude Hypoxia in the bA Hemoglobin Subunit of Yellow-Billed Pintails in the Andes | ||
|
Summary: elevated FST. Migration rates for the bA subunit alleles were approximately 1724 times smaller than... ) and the mitochondrial DNA control region. The bA subunit alleles of yellow-billed pintails were half as likely... protein of adult birds consists of two aA ... |
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|
Source: Johnson, Kevin P. - Illinois Natural History Survey |
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Collection: Environmental Sciences and Ecology |
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| 93 | Kinetic Evaluation of Cell Membrane Hydrolysis during Apoptosis by Human Isoforms of Secretory | ||
|
Summary: substrate access to adsorbed enzyme for the snake venom and group X isoforms corresponding to weakened lipid... the isoform and was always less than that observed with the AppD49 enzyme (AppD49 hGX hGV hGIIa 0). As shown... appear critical for different isoforms, it is also likely that ... |
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|
Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle |
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Collection: Chemistry ; Biology and Medicine |
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| 94 | The auxiliary subunit forms part of the functional multimeric neuronal voltage-dependent Ca channel (VDCC) | ||
|
Summary: with the â2a subunit and, to a lesser extent, with â1b. For â2a, the major effects of this deletion were... -expressed with auxiliary á2_ä andÏor â2a subunits Initially, we examined the biophysical properties of á1B subunits... . Biophysical properties of á1B and auxiliary á2_ä and ... |
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|
Source: Dolphin, Annette C. - Department of Neuroscience, Physiology and Pharmacology, University College London |
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|
Collection: Biology and Medicine |
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| 95 | Plant Molecular Biology 30: 1223-1232, 1996. 1996 Kluwer Academic Publishers. Printed in Belgium. 1223 | ||
|
Summary: of starch components by the lack of an isoform of starch branching enzyme in rice seeds. J Biol Chem 268... . Cell 35: 225- 233 (1983). 34. Smith AM: Major differences in isoforms of starch- branching enzyme... . 1223 Evolutionary conservation and expression patterns of maize starch branching ... |
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|
Source: Guiltinan, Mark - Department of Horticulture, Pennsylvania State University |
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|
Collection: Biotechnology |
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| 96 | The nuclear hormone receptor BgE75 links molting and developmental progression in the direct-developing insect Blattella germanica | ||
|
Summary: ) as model, we have cloned and characterized five isoforms of B. germanica E75, a member of the nuclear... receptor family participating in the 20E-triggered genetic hierarchy. The five isoforms present... tissue have shown that the five isoforms display specific 20E responsiveness. RNAi experiments in vivo |
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|
Source: Belles, Xavier - Institut de Biologia Evolutiva, Universitat Pompeu Fabra |
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Collection: Biology and Medicine |
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| 97 | Molecular Immunology 43 (2006) 18461854 The usage of alternative splice sites in mus musculus synaptotagmin-like 2 | ||
|
Summary: in the up-regulation of the synaptotagmin-like 2 gene. However, of the four known isoforms, only m... RNAs encoding the a and b isoforms accumulate. Two previously undected isoforms, each characterized... the Slp2-a and Slp2-b isoforms accumulate in large quantities in T-cells activated in presence of CSA |
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|
Source: Ecole Polytechnique, Centre de mathématiques |
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|
Collection: Mathematics |
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| 98 | Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger mediated | ||
|
Summary: is yotiao, an anchoring protein that directly interacts with the NR1A subunit of the NMDA receptor ion... ) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs). In the past... transmembrane receptors, G protein subunits, signal-generating enzymes, protein kinases ... |
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|
Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle |
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|
Collection: Biology and Medicine |
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| 99 | nature structural & molecular biology VOLUME 18 NUMBER 6 JUNE 2011 673 a rt i c l e s | ||
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Summary: majority of genes use alternative splicing to produce several protein isoforms. In eukaryotes, alternative... or degradation of an mRNA3, in most cases it will produce multiple and functionally diverse protein isoforms4... with the acquisition of metastatic potential7. Furthermore, a splicing switch in pyruvate kinase, a glycolytic ... |
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|
Source: Perreault, Jean-Pierre - Département de biochimie, Université de Sherbrooke |
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Collection: Biology and Medicine |
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| 100 | Dynamics of the Phosphoinositide 3-Kinase p110d Interaction with p85a and Membranes Reveals | ||
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Summary: ;mutations identified are located at two separate interfaces between the p110 catalytic and p85a subunits... . INTRODUCTION Phosphoinositide 3-kinases (PI3Ks) are a family of enzymes that catalyze the phosphorylation... mutations upregulate the enzyme activity by different mechanisms (Huang et al., 2008; ... |
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Source: Williams, Roger L. - Laboratory of Molecular Biology, MRC |
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Collection: Biology and Medicine |
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