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Sample search results for: a-subunit isoforms enzyme

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1 Nucleolar Proteome Database (http://www.lamondlab.com/NoPDB) August 2004 Acc # Acc # IPI Protein
 

Summary:  59344 HPBRII-4 mRNA Splicing related factor Q12874 IPI00029764 59154 Splicing factor 3A subunit 3... 23637 RNA modifying enzymes and related proteins P26599-1 IPI00179964 57357 Splice isoform 1 of P26599... modifying enzymes and related proteins P48729 IPI00183400 39118 Casein kinase I, ...

  

Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee

 

Collection: Biology and Medicine

 
2 Nucleolar Proteome Database (http://www.lamondlab.com/NoPDB) August 2004 Acc # Acc # IPI Protein
 

Summary:  /scleroderma autoantigen 2 RNA modifying enzymes and related proteins Q07244-1 IPI00216049 51230 Splice isoform 1 of Q07244... transcription factor 1 RNA polymerase Q12874 IPI00029764 59154 Splicing factor 3A subunit 3 Splicing related... 4 homolog RNA modifying enzymes and related ...

  

Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee

 

Collection: Biology and Medicine

 
3 Melittin induces both time-dependent aggregation and inhibition of Na,K-ATPase from duck salt glands however these two processes
 

Summary:  ,K-ATPase a-subunit as a result of enzyme aggregation (A) and loss of Na,K-ATPase activity (B) after... courses of melittin-induced loss of Na,K-ATPase a-subunit as a result of enzyme aggregation (A) and loss... at sequence MI(603)DPPRAT that is highly conserved for all isoforms of ...

  

Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
4 ORIGINAL ARTICLE doi:10.1111/j.1558-5646.2008.00483.x
 

Summary:  ORIGINAL ARTICLE doi:10.1111/j.1558-5646.2008.00483.x ENZYME ISOFORMS MAY INCREASE PHENOTYPIC... , Florida 32306 Received January 21, 2008 Accepted July 2, 2008 Enzyme isoforms are found in many cellular... , or in their reaction rates. The evolutionary significance of enzyme ...

  

Source: Bertram, Richard - Institute of Molecular Biophysics & Department of Mathematics, Florida State University; Houle, David - Department of Biological Science, Florida State University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology ; Mathematics

 
5 Eur. J. Biochem. 267, 20712078 (2000) q FEBS 2000 Effect of streptozotocin-induced diabetes on rat liver Na1
 

Summary:  .W., Koster, J., Xie, Z.J. & Mercer, R.W. (1994) The a-subunit of the Na,K-ATPase has catalytic activity... and K1 -activated phosphatase reside on different a-subunits. J. Biol. Chem. 273, 28813±28821. 47... in membrane fluidity as typically this enzyme will increase in response to an enhancement of membrane fluidity

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
6 Isolation of Six Putative P-typeATPase p SubunitPCR Fragmentsfrom the
 

Summary:  been made in the identification of isoforms of P-type ATPase subunits. Of the P-type ATPases... characterized, only the four cx subunit isoforms of Na,K-ATPaselor the two a subunit isoforms of the closely... related enzyme H,K-ATPase2are known to associate with p subunits. To date, studies investigating

  

Source: Cutler, Chris - Department of Biology, Georgia Southern University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
7 Role of Alternative Splicing in Generating Isoform Diversity Among Plasma Membrane Calcium Pumps
 

Summary:  Role of Alternative Splicing in Generating Isoform Diversity Among Plasma Membrane Calcium Pumps... Membrane Calcium Pump Isoforms 25 IV. Four Genes and Alternative Ribonucleic Acid Splicing Generate... a Multitude of Plasma Membrane Calcium Pump Isoforms 26 V. Alternative Splicing Options of Mammalian Plasma

  

Source: Zacharias, David A. - Whitney Laboratory for Marine Bioscience, University of Florida

 

Collection: Biology and Medicine

 
8 Differential trafficking of carboxyl isoforms of Ca2+ (Slo1) potassium channels
 

Summary:  Slo1 a-subunit. Fig. 5D shows immunoblots of anti-myc precipitates probed with antibodies for PP2A... CK2a0 O54833 41.216 8 24 PP2A-A subunit AAH52678 65.267 18 30 Tubulin, a1 AAH83344 50.120 15 28 c... Differential trafficking of carboxyl isoforms of Ca2+ -gated (Slo1) potassium channels Donghui Maa

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
9 371Fish Physiology and Biochemistry 17: 371376, 1997. 1997 Kluwer Academic Publishers. Printed in the Netherlands.
 

Summary:  in the Netherlands. Expression of Na+ ,K+ -ATPase subunit isoforms in the European eel (Anguilla anguilla) C... , University of St Andrews, St Andrews, Fife KY16 9TS, Scotland, UK Keywords: Anguilla anguilla, 2 isoform, 3... isoform, brain, cDNA, eel, mRNA, Na+ ,K+ -ATPase, nucleotide sequence, PCR Abstract Reverse transcriptase

  

Source: Cutler, Chris - Department of Biology, Georgia Southern University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
10 Role of homologous ASP334 and GLU319 in human non-gastric H,K-and Na,K-ATPases in cardiac glycoside binding
 

Summary:  in this group are the four isoforms (a1, a2, a3, and a4) of the a-subunit of Na,K-ATPase, the a-subunit... -Hess, Functional differences between a-subunit isoforms of the rat Na,K-ATPase expressed in Xenopus oocytes, J... of gastric proton pump or H,K-ATPase (aHKg) and the ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
11 pubs.acs.org/BiochemistryPublished on Web 02/16/2010r 2010 American Chemical Society Biochemistry 2010, 49, 25932603 2593
 

Summary:  Isoform of Snow Flea Antifreeze Protein, Yee-Foong Mok,§ Feng-Hsu Lin,§ Laurie A. Graham,§ Yeliz Celik... larger. This AFP is hyperactive and comprises two isoforms [Graham, L. A., and Davies, P. L. (2005... ) Science 310, 461]. The larger isoform (15.7 kDa) exhibits several-fold higher activity than the smaller

  

Source: Braslavsky, Ido - Department of Physics and Astronomy, Ohio University

 

Collection: Physics ; Materials Science

 
12 Light-Driven Translocation of the Protein Phosphatase 2A Complex Regulates Light/Dark Dephosphorylation of Phosducin and Rhodopsin
 

Summary:  , a significant increase in the immunoreactive protein level of the A, C, and B56epsilon PP2A subunits is observed... preparation of purified PP2A subunits for antibody production, the fractions from the HTP column containing... phosphorylated phosducin was pooled for analysis on preparative SDS-PAGE to ...

  

Source: Southern California, University of - Mary D. Allen Laboratories for Vision Research

 

Collection: Biology and Medicine

 
13 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS Vol. 332, No. 1, August 1, pp. 4757, 1996
 

Summary:  . In higher plants, it is a ubiquitous cytosolic enzyme. those of the larger Mr PEPC isoforms: (i) the anti... . Detection of Other Enzymes in Purified PEPC Fractions The HMM isoforms were not homogeneous prepara- tions... in the enzyme's oligomeric Metabolic Regulation of the Different ...

  

Source: Plaxton, William - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
14 Biochem. J. (2000) 351, 6777 (Printed in Great Britain) 67 Human 3-hydroxysteroid dehydrogenase isoforms (AKR1C1AKR1C4) of
 

Summary:  dehydrogenase (3- HSD) isoforms of the aldo-keto reductase (AKR) superfamily. The enzymes correspond to type 1 3... catalysed by homogeneous recombinant human 3-HSD isoforms Enzyme Km (µM) Vmax (nmol/min per mg) kcat (min-1... reduction and 20-hydroxy- steroid oxidation catalysed by homogeneous recombinant ...

  

Source: Jez, Joseph - Department of Biology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
15 Interaction of a Kinesin-like Protein with Calmodulin Isoforms from Arabidopsis*
 

Summary:  to KCBP, we examined the CaM-dependent enzyme activity of bovine brain PDE using AtCaM isoforms... Interaction of a Kinesin-like Protein with Calmodulin Isoforms from Arabidopsis* (Received... and other plants there are multiple calmodulin isoforms. However, the role of these iso- forms in regulating

  

Source: Reddy, A.S.N - Department of Biology, Colorado State University

 

Collection: Biology and Medicine ; Biotechnology

 
16 Neuron, Vol. 19, 185196, July, 1997, Copyright 1997 by Cell Press cAMP-Dependent Regulation of Cardiac L-Type Ca2
 

Summary:  - nase and facilitate phosphorylation reactions by localiz- channel 1C and 2a subunits and labeled... was that both the 1C and the 2a subunits were basally phosphor-campus neurons (Rosenmund et al., 1994... , an in- crease in phosphorylation of the 2a subunit was de- ...

  

Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle

 

Collection: Biology and Medicine

 
17 Comparative Biochemistry and Physiology Part B 151152 (2002) 185200 1096-4959/02/$ -see front matter 2002 Elsevier Science Inc. All rights reserved.
 

Summary:  systems. Phosphorylation of specific serine and threonine residues on the a- subunit by both protein... ) which are known to co-localise with the a-subunit have been implicated as potential regulators... . Increases in enzyme activity were apparent 3 h after the feeding event and peaked at 9 h before returning

  

Source: Cutler, Chris - Department of Biology, Georgia Southern University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
18 Identification of the Amino Terminus of Neuronal Ca2 Channel 1 Subunits 1B and 1E as an Essential Determinant
 

Summary:  - cessory 2- and 2a subunits in Xenopus oocytes and mam- malian (COS-7) cells. The 1Elong showed biophysical... (rbEII) was expressed with 2- but without 2a subunits in Xenopus oocytes (together with D2 dopamine receptors). Left... subunits. 1Elong was expressed with both 2- and 2a ...

  

Source: Dolphin, Annette C. - Department of Neuroscience, Physiology and Pharmacology, University College London

 

Collection: Biology and Medicine

 
19 Structural determinants of calcium channel subunit Hongyan Liu, Kevin f? Campbell
 

Summary:  by a,, subunits,[42]which have several isoforms (see table II) and appear to be expressed in several... of the cardiac calcium channel a, subunit gene generates developmentally regulated isoforms in the heart. Proc... . Molecular cloning of multiple subtypes of a ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
20 Functional diversity among a family of human skeletal muscle myosin motors
 

Summary:  muscle fibers correlate with the predominantly expressed MyHC isoform, but a functional analysis... of homogenous skeletal muscle myosin isoforms has not been possible. This is due to the difficulties... of separating the multiple isoforms usually coexpressed in muscle fibers, as well as the lack of an expression

  

Source: Spudich, James A. - Department of Biochemistry, Stanford University

 

Collection: Biology and Medicine


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21 Developmentally Regulated Switching of Titin Size Alters Myofibrillar Stiffness in the Perinatal Heart
 

Summary:  and mechanics of cardiac-titin isoforms during perinatal rat heart development. Gel electrophoresis... and immunoblotting revealed a single, 3.7-MDa, N2BA isoform present 6 days before birth and an additional, also... previously unknown, N2BA isoform of 3.5 to 3.6 MDa expressed in the near-term fetus. These large ...

  

Source: Leake, Mark C. - Department of Physics, University of Oxford

 

Collection: Physics ; Biology and Medicine

 
22 MOLECULAR AND CELLULAR BIOLOGY, Sept. 2003, p. 61296138 Vol. 23, No. 17 0270-7306/03/$08.00 0 DOI: 10.1128/MCB.23.17.61296138.2003
 

Summary:  . Molecular basis of competition between HSF2 and catalytic subunit for binding to the PR65/A subunit of PP2A... and phorbol esters (7), as well as the association of the phosphorylated histone isoform with immediate... activity among all human and yeast isoforms of PP2A (18), the regu- latory subunit is by ...

  

Source: Corces, Victor G. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
23 ABBREVIATIONS: AcCh, acetylcholine; a-BgTx, a-bungarotoxin; SOS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; MBTA, 4-(N-maleimido)benzyltnmethylammonium iodide; Endo F, endoglycosidase F; EDTA, ethylenediaminetetraacetic acid; BSA, bov
 

Summary:  of the lower molecular weight polypeptides and, at the highest enzyme concentration examined (a-subunit/V8, 5... enzyme concentration (a-subunit/V8, 15:1, w/w). The digestion pattern was not apparently modified... . MOLECULAR PHARMAcoLoGY, 29:649-656 Location of a Polypeptide Sequence within the ...

  

Source: Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
24 Second Messengers cAMP is Produced by the Enzyme _________________
 

Summary:  Second Messengers cAMP is Produced by the Enzyme _________________ Its Production and Subsequent... _____________, Phosphoinositides, Inositol triphosphate (IP3), Diacyl Glycerol and Nitric Oxide Enzymes that Generate Second... Isoforms have Different ______________________ and can Bind Different ________________ Different ...

  

Source: Cutler, Chris - Department of Biology, Georgia Southern University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
25 Characterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTIN1
 

Summary:  Characterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTI´N1 , JAUME BOSCH1 , JORDI... -like activity. This isoform can be easily obtained by solid phase synthesis methods. Our objective in this study... phase synthesis was employed for the synthesis of the 5 kDa GH isoform. Circular dichroism and limited

  

Source: Pompeu Fabra, Universitat - Departament de Ciències Experimentals i de la Salut, Proteomics and Protein Chemistry Unit

 

Collection: Biotechnology

 
26 8 Photoreceptor Phosphodiesterase (PDE6)
 

Summary:  G-protein, transducin. Following GDP­GTP exchange on the a-subunit of transducin and [Ca2+] DK... exchange of GDP (gray circle) for GTP (red circle), and formation of the activated transducin a-subunit... on the a-subunit, which is not subject to regulation by calcium. Rather, the GTPase rate is modulated

  

Source: Cote, Rick H. - Department of Biochemistry and Molecular Biology, University of New Hampshire

 

Collection: Biology and Medicine

 
27 The migrations of anadromous fish between freshwater and seawater represent remarkable transformations in the
 

Summary:  , as exhibited by the samples collected at Whonnock, was characterised by a significant increase in 1a subunit m... in enzyme activity has been proposed as predictive of the entry date into seawater (Nielsen et al., 2004... isoforms in response to seawater transfer and speculated that ...

  

Source: Cooke, Steven J. - Department of Biology, Carleton University; Farrell, Anthony P. - Faculty of Land and Food Systems, University of British Columbia; Hinch, Scott G. - Forest Sciences Department, University of British Columbia

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
28 Supplemental Data S1 mSin1 Is Necessary for Akt/PKB
 

Summary:  Supplemental Data S1 mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three... with the same enzymes. The resulting plasmid was named pMSCV-TAP. pMSCV-TAP was then cut with Xho... and Expression of Human mSin1 Isoforms Human mSin1 isoforms were cloned by RT-PCR from mRNA iso- lated from ...

  

Source: Sabatini, David M. - Whitehead Institute for Biomedical Research & Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
29 Structure/function analysis of Na -K -ATPase central isoform-specific region: involvement in PKC regulation
 

Summary:  -type 1 is inhibited. Interestingly, the 2-isoform resembles the truncated enzyme in this respect. How... and others have established the influence of the NH2-terminal region on isoform-specific enzyme kinet- ics... Structure/function analysis of Na -K -ATPase central isoform-specific ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
30 The Isoform-Specific Region of the Na,K-ATPase Catalytic Subunit: Role in Enzyme Kinetics and Regulation by Protein Kinase C
 

Summary:  The Isoform-Specific Region of the Na,K-ATPase Catalytic Subunit: Role in Enzyme Kinetics... component of the enzyme, is a membrane-spanning protein expressed as four isoforms (R1, R2, R3, and R4... enzyme at the plasma membrane is limitated by the amount of isoforms ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
31 Skeletal muscles exhibit considerable variability in their physiological properties, with muscle fiber type being coupled
 

Summary:  al., 1972). More recently, specific myosin heavy chain (MHC) isoforms present in different muscles... , 2002). Although single fibers expressing multiple MHC isoforms have sometimes been interpreted as being... expressing more than one myosin heavy chain (MHC) isoform at the level of fiber proteins and/or m

  

Source: Medler, Scott - Department of Biological Sciences, State University of New York at Buffalo

 

Collection: Biology and Medicine

 
32 A mathematical model for collagen fibre formation during foetal and adult dermal wound healing
 

Summary:  isoforms of the regulatory chemical transforming growth factor /3.Numerical simulations of the model lead... in adult wound healing. We investigate the effect of topical application of TGFP isoforms during healing... inactive (latent forms of TGFP isoforms are secreted by many cells (Martin et al. 1992 ; Streuli et al

  

Source: Maini, Philip K. - Centre for Mathematical Biology & Mathematical Institute, University of Oxford; Sherratt, Jonathan A. - Department of Mathematics, Heriot-Watt University

 

Collection: Biology and Medicine ; Mathematics

 
33 2 0 0 3 B J U I N T E R N A T I O N A L | 9 2 , 7 9 3 8 0 2 | doi:10.1046/j.1464-410X.2003.04460.x 7 9 3 Original Article
 

Summary:  and biogenesis of the enzyme complex [6]. The b1 isoform is ubiquitously expressed, whereas the b2 and b3... isoforms also have an effect on the biogenesis of the enzyme complex, and on the abundance and longevity... .04460.x 7 9 3 Original Article NA,K-ATPASE ISOFORMS IN RAT VENTRAL ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
34 Dynamics of Na Cotransporter
 

Summary:  for a cytosolic epitope, and reacts with all isoforms of the a- subunit of distant species. It was developed by D... M, Yu M, Hwang P. 1998. Isoform expression of the Naþ ,Kþ -ATPase a-subunit in gills of the teleost... . The abundance of NKA a-subunit protein also ...

  

Source: Cutler, Chris - Department of Biology, Georgia Southern University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
35 doi:10.1152/ajprenal.00089.2007 294:859-866, 2008. First published Dec 19, 2007;Am J Physiol Renal Physiol
 

Summary:  -K-ATPase -isoform diversity also plays a role in the ability of the enzyme to relay ouabain-induced signaling... Physiology onMay23,2008ajprenal.physiology.orgDownloadedfrom #12;Isoform specificity of Na... Pierre SV, Sottejeau Y, Gourbeau J-M, Sa´nchez G, Shidyak A, Blanco G. Isoform specificity of Na

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
36 Evaluation of the role of AMP-activated protein kinase and its downstream targets in mammalian hibernation
 

Summary:  cells (Salt et al., 1998). Also, the specificity of the a-subunit isoforms towards peptide substrates... in the activation loop of the a-subunits (Hawley et al., 1996) and phosphorylation at this site is both sufficient... polyclonal antibodies were from Santa Cruz. Anti-phospho Thr172 human AMPK a- ...

  

Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
37 Plant biotin-containing carboxylasesq Basil J. Nikolau,a,* John B. Ohlrogge,b
 

Summary:  of the fact that in most plants the plastidic isoform of ACCase is a heteromeric enzyme that is un- stable due... of the MCC-A and MCC-B subunits established that the MCC-A subunit contains BC and BCC functional domains... by the posttransla- tional biotinylation of the MCC-A ...

  

Source: Wurtele, Eve Syrkin - Department of Genetics, Development and Cell Biology, Iowa State University

 

Collection: Biotechnology ; Renewable Energy

 
38 Anne BENZINGER et al www.cell-research.com | Cell Research, 15(4):219-227, Apr 2005
 

Summary:  The crystal structure of the non-liganded 14-3-3 protein: insights into determinants of isoform specific... -3-3 isoform, a transcriptional target of p53, exerts its inhibitory effect on the cell cycle in the presence... of other 14-3-3 isoforms, which are constitutively expressed at high levels. In order to identify

  

Source: Hermeking, Heiko - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine

 
39 F-type and V-type reversible ATPases are membrane-associated molecular machines
 

Summary:  ,21 . The ion- translocating, membrane-spanning F0 sector is a complex of the integral-membrane a-subunit, two b... -bound c-subunits5,22­25 .The c-ring (rotor) is thought to slide along its interface with the a-subunit... V-type ATPases have one or two peripheral stalks15 . In addition to the large a-subunit and the c

  

Source: Steinhoff, Heinz-Jürgen - Fachbereich Physik, Universität Osnabrück

 

Collection: Biology and Medicine ; Physics

 
40 Ligand Binding and Phagocytosis by CD16 (Fc Receptor III) Isoforms
 

Summary:  by the cytoplasmic domain of Fc Rs, the phagocytosis of EA by CHO cells stably trans- fected with CD16A and CD16A-subunit... . The phagocytosis mediated by the CD16A-subunit chimeras expressed on CHO cells described in this report provides... Ligand Binding and Phagocytosis by CD16 (Fc Receptor III) Isoforms PHAGOCYTIC SIGNALING

  

Source: Zhu, Cheng - Department of Biomedical Engineering, Georgia Institute of Technology and Emory University

 

Collection: Engineering ; Biology and Medicine


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41 10.1261/rna.1611309Access the most recent version at doi: published online July 27, 2009RNA
 

Summary:  Zhou, Benjamin Czech, Julius Brennecke, et al. Loquacious isoform endo-siRNAs depends on a specific... .cshlp.orgDownloaded from #12;Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform RUI ZHOU,1... isoform, Loqs-PD, which is distinct from the one, Loqs-PB, required for the production of micro

  

Source: Higgins, Darren - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
42 Localization of Na,K-ATPase / Isoforms in Rat Sciatic Nerves: Effect of Diabetes and Fish Oil Treatment
 

Summary:  Localization of Na,K-ATPase / Isoforms in Rat Sciatic Nerves: Effect of Diabetes and Fish Oil... ,K-ATPase isoforms. Some of these changes could be prevented by fish oil therapy. The aim of this study... ,K-ATPase-- Isoforms--Immunocytochemistry--Confocal laser scan- ning microscopy--Image analysis--Diabetes--Dietary fish

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
43 Different Anesthetic Sensitivities of Skeletal and Cardiac Isoforms of the Brad S. Karon, Joseph M. Autry, Yongli Shi, Christine E. Garnett,| Giuseppe Inesi,| Larry R. Jones,
 

Summary:  ) or (b) activate the SERCA 1 isoform. The finding that anesthetic interaction with enzyme isoforms... that halothane interacts directly with the SERCA 2a isoforms of the Ca- ATPase to inhibit the enzyme. Inhibition... Different Anesthetic Sensitivities of Skeletal and Cardiac ...

  

Source: Thomas, David D. - Departments of Biochemistry, Molecular Biology, & Biophysics, University of Minnesota

 

Collection: Biology and Medicine

 
44 Alternatively spliced isoforms of the human constitutive androstane receptor
 

Summary:  Alternatively spliced isoforms of the human constitutive androstane receptor Scott S. Auerbach... of genes encoding xenobiotic- and steroid- metabolizing enzymes. Regulatory processes that are mediated... protein isoform, exhibit compromised activities with respect to DNA binding, transcriptional activation

  

Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
45 Hypertrophy of colonic smooth muscle: contractile proteins, shortening velocity, and regulation
 

Summary:  in the contractile protein isoform composition. 1) There is a higher actin concentration in megacolon, primarily... caused by a larger proportion of y-isoforms. 2) There was no difference in myosin concentration or in SMl... isoforms and the lack of a simple relationship between myosin light chain phosphorylation and V, point

  

Source: Trinkle-Mulcahy, Laura - Department of Cellular and Molecular Medicine, University of Ottawa

 

Collection: Biology and Medicine

 
46 The cGMP Signaling Pathway in Retinal Photoreceptors and the Central Role of
 

Summary:  that are farnesylated (a-subunit) or geranylgeranylated (~-subunit). The enzyme-active site is denoted by the notch... diphosphate (GDP) for guanosine triphosphate (GTP), and formation of the activated transducin a-subunit... ]. This interaction catalyzes the exchange of bound GDP for GTP on the transducin ...

  

Source: Cote, Rick H. - Department of Biochemistry and Molecular Biology, University of New Hampshire

 

Collection: Biology and Medicine

 
47 THE JUNCTIONAL SARCOPLASMIC RETICULUM PROTEIN JP-45 AFFECTS THE FUNCTIONAL EXPRESSION OF THE VOLTAGE DEPENDENT CALCIUM CHANNEL
 

Summary:  defined (Catterall, 1995; Snutch and Reiner, 1992, Tsien et al., 1991). The ß1a subunit associates tightly... ) (Pragnell et al., 1994). The ß1a-subunit is important for plasma membrane expression of the 1.1 subunit... -terminal domains of 1.1 subunit as well as with the ß1a subunit. In ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
48 Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4 and 6 in distinct membrane microdomains
 

Summary:  Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4 and 6 in distinct... 115 Memphis, TN 38163 (901) 448-1181 rostrom@uthsc.edu Running title: Adenylyl cyclase isoforms... activity and increase airway diameter. We assessed expression of AC isoforms in human bronchial smooth

  

Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center

 

Collection: Biology and Medicine

 
49 The Phosphorylation State of Translation Initiation Factors Is Regulated Developmentally and following Heat Shock in Wheat*
 

Summary:  isoforms, whereas a lower level of the enzyme resulted in a partial conversion of the basic cluster... % the level of the basic form. The acidic and basic isoforms correspond well with the monophosphorylated (pI 5... to be modified by phosphorylation (31). The nonphosphorylated and phosphorylated isoforms ...

  

Source: Tullos, Desiree - Department of Biological and Ecological Engineering, Oregon State University

 

Collection: Environmental Sciences and Ecology

 
50 Protein phosphorylation is recognized as a widespread and highly versatile regulatory mechanism that controls
 

Summary:  from one gene3 . Note that the B class of PP2A subunits includes B, B, B and B (see main text... by binding the B55 and B56 subunits49 . In S. cerevisiae, PP2A subunits display dynamic localization patterns... that certain Ser/Thr- specific enzymes can dephosphorylate Tyr, and that many ...

  

Source: Trinkle-Mulcahy, Laura - Department of Cellular and Molecular Medicine, University of Ottawa

 

Collection: Biology and Medicine

 
51 Separate Na,K-ATPase genes are required for otolith formation and semicircular canal development in zebrafish
 

Summary:  and indicate that different isoforms play distinct functional roles in formation of inner ear structures. Our... RNA rescue Introduction Na,K-ATPase, also known as the sodium pump, is a key enzyme essential for maintaining... solutes and water across epithelia (Thomas, 1972). The active enzyme is a major consumer of ATP

  

Source: Dickman, J. David - Department of Anatomy and Neurobiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
52 Associate editor: Neve Sensitization of adenylate cyclase by Gai/o-coupled receptorsB
 

Summary:  as a locus for the expression of the sensitized adenylate cyclase response, and to isoform... abuse; Adenylate cyclase Abbreviations: AC1­9, adenylate cyclase isoforms 1 through 9; AGS, activator... .2. Multiple adenylate cyclase isoforms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 1

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
53 Molecular and Biochemical Parasitology 99 (1999) 167181 Characterization of protein Ser/Thr phosphatases of the malaria
 

Summary:  enzymes preferred to dephosphorylate the a-subunit of phosphorylase kinase to the b-subunit (Fig. 2... - rylase kinase by PfPP2A (, b-subunit; , a-subunit) and PfPP2B ( , b-subunit; , a-subunit) was carried... cytosolic extracts of the erythrocytic stage of the malaria parasite, Plasmodium falciparum. Both ...

  

Source: Fairlamb, Alan - Division of Biological Chemistry and Molecular Microbiology, University of Dundee

 

Collection: Biology and Medicine

 
54 J Cell Sci. Author manuscript The junctional SR protein JP-45 affects the functional expression of the
 

Summary:  defined ( ; , Catterall, 1995 Snutch and Reiner, 1992 Tsien et al., ). The 1a subunit associates tightly... (AID) ( ). The 1a-subunit is important for plasma membrane expression of the 1.1 subunit whereas a... directly with the I II loop, the COOH-terminal domains of 1.1 subunit­ as well as with the 1a ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
55 BIOCHEMICAL ADAPTATION KENNETH B. STOREY
 

Summary:  .5 of the enzyme to a value that closely matches in vivo F6P concentrations (0.16 mM) in working muscle. ISOFORM... enzyme/protein form, and in many cases, isozymes/isoforms have evolved that may differ in kinetic... isoforms, a wide variety of specialized needs and organ- specific ...

  

Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
56 BIOCHEMICAL ADAPTATION KENNETH B. STOREY
 

Summary:  on an enzyme or pro- tein cannot always be met by a single enzyme/protein form, and in many cases, isozymes/isoforms... proteins (e.g., enzymes, transporter proteins), and the integrated functioning of the biochemical reactions... and catalysis in enzymes. A decrease in temperature ...

  

Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
57 C-Terminal Cleavage of Np63 Is Associated with TSA-Induced Apoptosis in Immortalized Corneal
 

Summary:  Gene-specific primers for each isoform, including restriction enzyme sites, are listed in Table 1. A 50... desquamation, suggesting a potential role for Np63 isoforms in mediating surface cell apoptotic shedding... . In this study, the authors investigated a role for Np63 isoforms in caspase-mediated ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
58 Structure of the Rat Inhibin and Activin A-Subunit Gene and Regulation in an Ovarian Granulosa Cell Line*
 

Summary:  both the 5 and 3 ends of the rat A-subunit cDNA clone rINB-5 (8). A combination of restric- tion enzyme... Structure of the Rat Inhibin and Activin A-Subunit Gene and Regulation in an Ovarian Granulosa Cell... the rat inhibin and activin A-subunit gene, which is composed of three exons, and have characterized ...

  

Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
59 FRET evidence that an isoform of caspase-7 binds but does not cleave its substrate
 

Summary:  FRET evidence that an isoform of caspase-7 binds but does not cleave its substrate Isaac T.S. Li a... Fluorescent resonance energy transfer (FRET) Enzyme kinetics a b s t r a c t A caspase-7 biosensor (v... decrease of 61%. In contrast, an isoform with the 23 N- terminal residues truncated (24casp7) bound to v

  

Source: 

 

Collection: Biotechnology ; Engineering

 
60 Binding assays of inhibitors towards selected V-ATPase domains F. Fernandesa
 

Summary:  -subunits from enzymes of different origins. A possible explanation would be the participation of the a-subunit... (part of the enzyme membrane bound domain--V0) (Fig. 1A) in the inhibitory mechanism, since the isoform... to bind to these as strongly as to the entire V0 domain, apparently excluding a ...

  

Source: Hemminga, Marcus A. - Department of Molecular Physics, Wageningen Universiteit

 

Collection: Physics ; Biology and Medicine


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61 -Subunit of cardiac Na -K -ATPase dictates the concentration of the functional enzyme in caveolae
 

Summary:  in cardiac myocytes. J Biol Chem 271: 10372­ 10378, 1996. 31. Periyasamy SM, Huang WH, and Askari A. Subunit... -Subunit of cardiac Na -K -ATPase dictates the concentration of the functional enzyme in caveolae... of the functional enzyme in caveo- lae. Am J Physiol Cell Physiol 291: C569­C578, 2006. First ...

  

Source: Askari, Amir - Department of Biochemistry & Cancer Biology, University of Toledo; Askari, Amir - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
62 doi:10.1152/ajpcell.00158.2007 293:1489-1497, 2007. First published Aug 29, 2007;Am J Physiol Cell Physiol
 

Summary:  Physiol 287: H2173­ H2182, 2004. 30. Liu L, Askari A. -Subunit of cardiac Na -K -ATPase dictates... the plasma membranes of most mammalian cells, and this pumping function of the enzyme is specifically... and assayed for the 1-subunit of Na -K -ATPase, since this isoform is pre- dominant in cardiac myocytes

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
63 Functional Interactions between Heterologously Expressed Starch-Branching Enzymes of Maize and the Glycogen
 

Summary:  SBE isoforms of maize (Zea mays) away from the other plant enzymes involved in starch biosynthesis... typically requires a single isoform of the glucan synthase and branching enzyme activities. Starch... of these enzymes. In maize (Zea mays), there are at least five SS ...

  

Source: Scott, Paul - Department of Agronomy, Iowa State University

 

Collection: Biotechnology

 
64 BIOINFORMATICS Vol. 19 Suppl. 1 2003, pages i118i121 DOI: 10.1093/bioinformatics/btg1015
 

Summary:  recently shown that a third of reliably-inferred alternative mRNA isoforms are candidates for nonsense... a single genetic locus to generate multiple mRNA isoforms, and it affects over a third (Brett et al., 2000... of alternative isoforms. Using the human genome sequence, databases of expressed sequence tags (ESTs

  

Source: Brenner, Steven E. - Department of Plant and Microbial Biology, University of California at Berkeley

 

Collection: Biotechnology

 
65 Exploring Uncoupling Proteins and Antioxidant Mechanisms under Acute Cold Exposure in Brains of Fish
 

Summary:  activates the expression of antioxidant enzymes, including SOD and GPx [33]. To date, three PPAR isoforms... (GLUTs) Western blot analysis with antibodies against the fish HIF-1a subunit demonstrates... (Lepomis cyanellus) demonstrates elevated activities of glycolytic enzymes, such as ...

  

Source: Academia Sinica, Institute of Atomic and Molecular Sciences, High-Field Physics and Ultrafast Technology Laboratory

 

Collection: Physics

 
66 Transport and Pharmacological Properties of Nine Different Human Na,K-ATPase Isozymes*
 

Summary:  significantly differed depending on the but not on the isoform present in the enzyme complex (Table I... and isoforms, were expressed in Xe- nopus oocytes and were analyzed for their transport and pharmacological... are functional but differ in their turn- over rates depending on the isoform. On the other ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
67 Coefficients for Active Transport and Thermogenesis of Ca2 Signe Kjelstrup,* Daniel Barragan, and Dick Bedeaux
 

Summary:  manner different performances of the enzyme isoforms. Four enzyme isoforms are examined, namely from... for this enzyme, in addition to the role played by the uncoupling protein. The existing isoforms may not have... Coefficients for Active Transport and Thermogenesis ...

  

Source: Kjelstrup, Signe - Department of Chemistry, Norwegian University of Science and Technology

 

Collection: Chemistry

 
68 2007LANDESBIOSCIENCE.DONOTDISTRIBUTE. [Cancer Biology & Therapy 6:10, 1-5, EPUB Ahead of Print: http://www.landesbioscience.com/journals/cbt/article/4787; October 2007]; 2007 Landes Bioscience
 

Summary:  Research Paper Novel Splice Isoforms of STRAD Differentially Affect LKB1 Activity, Complex Assembly... to differentiate in vitro. We report herein the discovery of several novel splice isoforms of STRAD... associates with the chromatin remodeling enzyme Brg1 and mediates progres- sion of cells through the G1 phase

  

Source: Marignani, Paola - Department of Biochemistry and Molecular Biology, Dalhousie University

 

Collection: Biology and Medicine

 
69 Isoform-specific 3'-untranslatedSequences Sort a-cardiac and/3-cytoplasmic ActinMessenger
 

Summary:  Isoform-specific 3'-untranslatedSequences Sort a-cardiac and/3-cytoplasmic ActinMessenger RNAs... . We demonstrate that in differentiating myo- blasts, the mRNAs encoding two actin isoforms... specific for each isoform. To address the mechanism of isoform-specific mRNA localization, molecular

  

Source: Singer, Robert H. - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
70 Bradfield; Mechanisms of Liver Carcinogenesis 10 UNIT III: Metabolism and Modifiers of Chemical Carcinogenesis
 

Summary:  group of Phase II enzymes has coevolved. Phase II enzymes are best described as conjugating... or "synthetic" enzymes. They are classified by the fact that they conjugate large molecules onto chemical... substrates. The reason they are called Phase II arises from the observation that these enzymes usually ...

  

Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
71 Unique Profile of Chicken Adiponectin, a Predominantly Heavy Molecular Weight Multimer,
 

Summary:  , circulates as heavy, medium, and light molecular weight isoforms in mammals. Plasma heavy molecular weight... (HMW) adiponectin isoform levels are inversely correlated with the incidence of type 2 diabetes... conditions, adiponectin in chicken plasma, and adipose tissue is predominantly a multimeric HMW isoform

  

Source: Ramachandran, Ramesh - Department of Veterinary and Biomedical Sciences, Pennsylvania State University

 

Collection: Biology and Medicine

 
72 INTRODUCTION Hundreds of protein kinases and protein phosphatases are
 

Summary:  cellular events, including division, signalling, differentiation and metabolism. These enzymes... for proteins that bring the enzyme in proximity to the substrate. These proteins have been termed `targeting... isoforms (, / and 1), each encoded by distinct genes, in the mammalian cell (Sasaki et al., 1990; Barker et

  

Source: Lamond, Angus I. - Wellcome Trust Centre for Gene Regulation and Expression, University of Dundee

 

Collection: Biology and Medicine

 
73 The l l0-kD Spindle Pole Body Component of SaccharomycescerevisiaeIs a Phosphoprotein That Is Modified in a Cell Cycle-dependent Manner
 

Summary:  body (SPB). Asynchronous wild-type cultures con- tain two electrophoretically distinct isoforms... isoforms in- corporate 32pi in vivo, suggesting that Spcll0p is post- translationally modified... by phosphorylation. The slower-migrating 120-kD Spcll0p isoform is converted to the faster-migrating ll2-kD ...

  

Source: Davis, Trisha N. - Department of Biochemistry, University of Washington at Seattle

 

Collection: Biology and Medicine ; Environmental Management and Restoration Technologies

 
74 BioMed Central Page 1 of 14
 

Summary:  the relation- ships of the enzymes found in other eukaryotes, particu- larly to determine if isoforms found... by two invariant Cys pairs in all known APRs [6]. However, a novel isoform of the enzyme from the moss... of host origin. The many distinct isoforms of the three ...

  

Source: Durnford, Dion G. - Biology Department, University of New Brunswick

 

Collection: Biology and Medicine

 
75 Identification of Three Subunits of the High Affinity -Conotoxin MVIIC-sensitive Ca2
 

Summary:  products (1, 12, 22, 23). Since the activity of 1A subunits expressed in Xenopus oocytes can be blocked... (45 pM) was used to specifically label the high affinity -CTX MVIIC receptor. Polyclonal 1A subunit... little homology with the 1a subunit of skeletal muscle ...

  

Source: Campbell, Kevin P. - Department of Physiology and Biophysics, University of Iowa

 

Collection: Biology and Medicine

 
76 J Physiol 577.1 (2006) pp 339352 339 Fibre type-specific increase in passive muscle tension
 

Summary:  , elevated PT was found in cells expressing fast myosin heavy chain (MyHC) isoforms, especially My... -linking status and isoform composition, and the titin isoform expression pattern are believed to be the major... ; Prado et al. 2005). Titin isoform size and stiffness are highly variable among fast-twitch ...

  

Source: Linke, Wolfgang A. - Fachbereichs Biologie, Westfälische Wilhelms-Universität Münster

 

Collection: Biology and Medicine

 
77 -ATPase as a signal transducer Zijian Xie and Amir Askari
 

Summary:  , 429­437. 24. Huang, L., Kometiani, P. & Xie, Z. (1997) Differential regulation of Na/K-ATPase a-subunit... and expression of various genes, only in recent years the mechanisms through which this plasma membrane enzyme... to establish that this enzyme is indeed the molecular machine that uses the energy of hydrolysis of ATP

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
78 ORIGINAL PAPER Lifetime-and caste-specific changes in flight metabolic rate
 

Summary:  in troponin T isoforms and increases in flight muscle maximal activities (Vmax) of the enzymes citrate... in the in vitro Vmax of these flight muscle metabolic enzymes. Estimates of in vivo flux (v) compared to maximum... flux of each enzyme in vitro (fractional velocity, v/Vmax) suggest that most ...

  

Source: Dukas, Reuven - Department of Psychology, McMaster University

 

Collection: Environmental Sciences and Ecology

 
79 r XXXX American Chemical Society A dx.doi.org/10.1021/jm101007q |J. Med. Chem. XXXX, XXX, 000000 pubs.acs.org/jmc
 

Summary:  enzyme that may exist in ve isoforms (hLDH1-5), mostly located in the cytosol. There are only two types... .19 An ampli ed expression of this gene, measured as LDH-A subunit increased production, was found... as a tractable anticancer strategy. The X-ray crystal structure of the LDH-A ...

  

Source: Hergenrother, Paul J. - Department of Chemistry, University of Illinois at Urbana-Champaign

 

Collection: Chemistry

 
80 Skeletal muscles differ significantly in their contractile properties, largely because of differences in myofibrillar
 

Summary:  of differences in myofibrillar protein isoforms among various fibers (Schiaffino and Reggiani, 1996). Crustacean... isoforms present in a particular fiber (Mykles, 1985a,b, 1988, 1997). Through these methods, crustacean... activity (Oganowski and Lang, 1979; Silverman et al., 1987) and a number of distinct myofibrillar isoforms

  

Source: Medler, Scott - Department of Biological Sciences, State University of New York at Buffalo

 

Collection: Biology and Medicine


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81 THEJOURNALOF BIOLOGICAL CHEMISTRY 0 1988by The American Society for Biochemistry and MolecularBiology, Inc.
 

Summary:  Regulation of Tropoelastin Isoforms* (Receivedfor publication, September 29, 1987) William C. Parks... The production of tropoelastin isoforms was exam- ined by cell-free translation of nuchal ligament RNA from cows... isoform patterns were detected at different devel- opmental periods. 1) The fetal period was character

  

Source: Mecham, Robert - Center for Cardiovascular Research & Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
82 Molecular and Cellular Endocrinology 171 (2001) 137149 Structure-function aspects and inhibitor design of type 5
 

Summary:  -HSD). This enzyme shares 69% sequence identity with AKR1C3 and serves as a good model for this human isoform. AKR1C9... ) superfamily; it is formally AKR1C3. In vitro the homogeneous recombinant enzyme expressed in Escherichia coli... -hydroxysteroid oxidase. The enzyme will reduce 5a-DHT, D4 ...

  

Source: Jez, Joseph - Department of Biology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
83 Marcella Martignoni1, Ruben de Kanter2 and Geny Groothuis3 1 Preclinical Development, Nerviano Medical Sciences, Viale Pasteur 10, 20014 Nerviano (MI),
 

Summary:  , it is important to realize that humans differ from animals in isoform composition, expression and catalytic... activities of enzymes involved in drug metabolism. In fact, even small changes in the amino acid sequences... of these enzymes can give rise to profound differences in substrate specificity and catalytic activity. ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
84 Research report The circadian clock-containing photoreceptor cells in Xenopus laevis
 

Summary:  several isoforms of casein kinase I Cara M. Constancea,c,1 , Jin-Yuan Fanb,1 , Fabian Preussb , Carla B... for the analysis of retinal circadian rhythms. In this paper, several isoforms of X. laevis casein kinase I (CKI... variants of CKIy (a full-length form and deletion isoform, which is missing an exon that encodes a putative

  

Source: Phillips, Kimberley A. - Department of Biology, Hiram College

 

Collection: Biology and Medicine

 
85 J Comp Physiol B DOI 10.1007/s00360-011-0600-4
 

Summary:  ) at the Uni- versity of British Columbia--Okanagan (Kelowna, BC, Canada). The 1a subunit sequence showed 100... % sequence similarity to the O. mykiss NKA 1a subunit (GenBank Accession No. NM_001124461.1). The 1b subunit... . Accompanying the move- ment from seawater to freshwater was a signiWcant increase in ...

  

Source: Farrell, Anthony P. - Faculty of Land and Food Systems, University of British Columbia; Hinch, Scott G. - Forest Sciences Department, University of British Columbia

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
86 Annu. Rev. Physiol. 2001. 63:87194 Copyright c 2001 by Annual Reviews. All rights reserved
 

Summary:  , mutations, resurgent current s Abstract A variety of isoforms of mammalian voltage-gated sodium channels... of those isoforms have been functionally expressed in exogenous sys- tems. The subunit is associated... . The subunit isoforms have distinct patterns of development and localization in the nervous system, skeletal

  

Source: Goldin, Alan L. - Department of Microbiology and Molecular Genetics, University of California, Irvine

 

Collection: Biology and Medicine

 
87 Biochem. J. (1999) 343, 443452 (Printed in Great Britain) 443 Mechanism of A-kinase-anchoring protein 79 (AKAP79) and protein
 

Summary:  79 also associates with conventional, novel and atypical isoforms of PKC in itro and in i o... . Recently, targeting of these signalling enzymes to precise subcellular locations has emerged as a mechanism... three signalling enzymes to postsynaptic sites and has been proposed to function as a signalling

  

Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle

 

Collection: Biology and Medicine

 
88 Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A
 

Summary:  -cytoplasmic domain cDNAs into pMAL vector disrupts expression of b-galactosidase a-subunit located at the downstream... to the PP2A- Ar-a isoform from CAD-NET cells, but none from parental CAD cells. In order to verify... /f, and one of e iso- forms from CAD-NET cells. In contrast, we recovered only one peptide from g isoform ...

  

Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University

 

Collection: Biology and Medicine

 
89 *Corresponding Author: Steven E. Brenner--Department of Molecular and Cell Biology, University of California, Berkeley. Email: brenner@compbio.berkeley.edu
 

Summary:  + isoform occurs when polyamine levels are low--a condition where the enzyme is not needed. Upon depletion... in humans result in mRNA isoforms thatharboraprematureterminationcodon... (PTC).Thesetranscriptsarepredictedtobedegraded by the nonsensemediated mRNA decay (NMD) pathway. One explanation for the abundance of PTCcontaining ...

  

Source: Brenner, Steven E. - Department of Plant and Microbial Biology, University of California at Berkeley

 

Collection: Biotechnology

 
90 Expression of a duplicate Na,K-ATPase 1-isoform in the European eel (Anguilla anguilla)
 

Summary:  - and -isoform combinations have been shown to produce active enzymes with the ion specific- ity determined... suggest that the 233-isoform is an integral component of the Na,K-ATPase enzyme that is expressed... Expression of a duplicate Na,K-ATPase 1-isoform in the European eel (Anguilla ...

  

Source: Cutler, Chris - Department of Biology, Georgia Southern University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
91 Vacuolar and Plasma Membrane Proton-Adenosinetriphosphatases
 

Summary:  and Function of Vacuolar Proton-Adenosinetriphosphatases 363 A. Subunits definition and mechanism of action 363... evolution. II. SUBUNIT STRUCTURE AND FUNCTION OF VACUOLAR PROTON- ADENOSINETRIPHOSPHATASES A. Subunits... but are not part of the final complex. 2. Catalytic subunits A) ...

  

Source: Nelson, Nathan - Department of Biochemistry, Technion, Israel Institute of Technology

 

Collection: Biology and Medicine

 
92 Gene Flow in the Face of Countervailing Selection: Adaptation to High-Altitude Hypoxia in the bA Hemoglobin Subunit of Yellow-Billed Pintails in the Andes
 

Summary:  elevated FST. Migration rates for the bA subunit alleles were approximately 17­24 times smaller than... ) and the mitochondrial DNA control region. The bA subunit alleles of yellow-billed pintails were half as likely... protein of adult birds consists of two aA ...

  

Source: Johnson, Kevin P. - Illinois Natural History Survey

 

Collection: Environmental Sciences and Ecology

 
93 Kinetic Evaluation of Cell Membrane Hydrolysis during Apoptosis by Human Isoforms of Secretory
 

Summary:  substrate access to adsorbed enzyme for the snake venom and group X isoforms corresponding to weakened lipid... the isoform and was always less than that observed with the AppD49 enzyme (AppD49 hGX hGV hGIIa 0). As shown... appear critical for different isoforms, it is also likely that ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
94 The auxiliary subunit forms part of the functional multimeric neuronal voltage-dependent Ca channel (VDCC)
 

Summary:  with the â2a subunit and, to a lesser extent, with â1b. For â2a, the major effects of this deletion were... -expressed with auxiliary á2_ä andÏor â2a subunits Initially, we examined the biophysical properties of á1B subunits... . Biophysical properties of á1B and auxiliary á2_ä and ...

  

Source: Dolphin, Annette C. - Department of Neuroscience, Physiology and Pharmacology, University College London

 

Collection: Biology and Medicine

 
95 Plant Molecular Biology 30: 1223-1232, 1996. 1996 Kluwer Academic Publishers. Printed in Belgium. 1223
 

Summary:  of starch components by the lack of an isoform of starch branching enzyme in rice seeds. J Biol Chem 268... . Cell 35: 225- 233 (1983). 34. Smith AM: Major differences in isoforms of starch- branching enzyme... . 1223 Evolutionary conservation and expression patterns of maize starch branching ...

  

Source: Guiltinan, Mark - Department of Horticulture, Pennsylvania State University

 

Collection: Biotechnology

 
96 The nuclear hormone receptor BgE75 links molting and developmental progression in the direct-developing insect Blattella germanica
 

Summary:  ) as model, we have cloned and characterized five isoforms of B. germanica E75, a member of the nuclear... receptor family participating in the 20E-triggered genetic hierarchy. The five isoforms present... tissue have shown that the five isoforms display specific 20E responsiveness. RNAi experiments in vivo

  

Source: Belles, Xavier - Institut de Biologia Evolutiva, Universitat Pompeu Fabra

 

Collection: Biology and Medicine

 
97 Molecular Immunology 43 (2006) 18461854 The usage of alternative splice sites in mus musculus synaptotagmin-like 2
 

Summary:  in the up-regulation of the synaptotagmin-like 2 gene. However, of the four known isoforms, only m... RNAs encoding the a and b isoforms accumulate. Two previously undected isoforms, each characterized... the Slp2-a and Slp2-b isoforms accumulate in large quantities in T-cells activated in presence of CSA

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
98 Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger mediated
 

Summary:  is yotiao, an anchoring protein that directly interacts with the NR1A subunit of the NMDA receptor ion... ) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs). In the past... transmembrane receptors, G protein subunits, signal-generating enzymes, protein kinases ...

  

Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle

 

Collection: Biology and Medicine

 
99 nature structural & molecular biology VOLUME 18 NUMBER 6 JUNE 2011 673 a rt i c l e s
 

Summary:  majority of genes use alternative splicing to produce several protein isoforms. In eukaryotes, alternative... or degradation of an mRNA3, in most cases it will produce multiple and functionally diverse protein isoforms4... with the acquisition of metastatic potential7. Furthermore, a splicing switch in pyruvate kinase, a glycolytic ...

  

Source: Perreault, Jean-Pierre - Département de biochimie, Université de Sherbrooke

 

Collection: Biology and Medicine

 
100 Dynamics of the Phosphoinositide 3-Kinase p110d Interaction with p85a and Membranes Reveals
 

Summary:  ;mutations identified are located at two separate interfaces between the p110 catalytic and p85a subunits... . INTRODUCTION Phosphoinositide 3-kinases (PI3Ks) are a family of enzymes that catalyze the phosphorylation... mutations upregulate the enzyme activity by different mechanisms (Huang et al., 2008; ...

  

Source: Williams, Roger L. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine


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