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Sample search results for: 2-adrenergic receptor stimulation

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1 Perspectives in Pharmacology In Vivo Gene Modification Elucidates Subtype-Specific
 

Summary:  of the three 2-adrenergic receptor subtypes because of the lack of sufficiently subtype... with these mice indicate that most of the classical functions mediated by the 2-adrenergic receptor... - type-specific functions in different mouse strains by altering the same ...

  

Source: Kable, Joe - Center for Cognitive Neuroscience & Department of Psychology, University of Pennsylvania

 

Collection: Biology and Medicine

 
2 Alpha2-adrenergic Receptors and Lysophosphatidic Acid Release from Fat Cells 1431 J. Clin. Invest.
 

Summary:  Alpha2-adrenergic Receptors and Lysophosphatidic Acid Release from Fat Cells 1431 J. Clin. Invest... 1998, 1431­1438 http://www.jci.org Alpha2-adrenergic Receptor­mediated Release of Lysophosphatidic Acid... ­dependent trophic activities of the conditioned media and ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
3 The Rockefeller University Press, 0021-9525/99/05/927/6 $2.00 The Journal of Cell Biology, Volume 145, Number 5, May 31, 1999 927932
 

Summary:  with agonist-activated 2-adrenergic receptors, as assessed by immunofluorescence and coimmunoprecip- itation... ­mediated association of Src with 2-adrenergic receptors is a key step in mitogenic signaling by these receptors, since... inhibi- ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
4 INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE Olfactory Receptor Interactions
 

Summary:  was achieved via coexpression with the Gs-coupled 2- adrenergic receptor, stimulation with the M71... improve M71 surface trafficking upon coex- pression: the 2-adrenergic receptor, P2Y1 and P2Y2 purinergic... for mock-transfected HEK-293 cells ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
5 Seminars in Cell & Developmental Biology 15 (2004) 281288 -Adrenergic receptors and their interacting proteins
 

Summary:  , Jones L, Livingston B, Ziman B, et al. Beta 2-adrenergic receptor-stimulated increase in cAMP in rat... sequestration of the beta(2)-adrenergic receptor: insulin stimulates pp60Src phosphorylation and activation. Mol... . ARs can also ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
6 LPA as a Paracrine Mediator of Adipocyte Growth and Function Cline Pagsa, Alexia Girarda, Olivier Jeannetona, Pierre Barbea, Claude Wolf b, Max
 

Summary:  . This production is modulated by catecholamines via 2-adrenergic receptors. Adipocyte-LPA present in conditionned... author manuscript Ann N Y Acad Sci 04/2000; 905 159-64 #12;2 adrenergic receptors in the control... of adipocyte express abundant functional ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
7 School of Life Sciences School of Engineering IBI Institute of Bioengineering / Institut de bioingnierie
 

Summary:  endocytosis) has received little attention. Here we show that two prototypical class I GPCRs, the 2 adrenergic... ibi@epfl.ch http://ibi.epfl.ch/ IBI SEMINAR ANNOUNCEMENT "G protein-coupled receptors trafficking... . Aleksandra Radenovic G-protein coupled receptors (GPCRs) belong to a superfamily of plasma ...

  

Source: Floreano, Dario - Laboratory of Intelligent Systems, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Computer Technologies and Information Sciences ; Engineering

 
8 G Protein-coupled Receptors II. MECHANISM OF AGONIST ACTIVATION*
 

Summary:  of dimer formation were observed for different receptors ( 2 adrenergic receptor (22), the -opioid receptor... of both the 1b adrenergic receptor (14, 26) and the 2 adrenergic receptor.2 Similarly, ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
9 Ca++-Independent Phospholipase A2 (iPLA2) is required for 2-adrenergic-induced preadipocyte spreading.
 

Summary:  of lipolysis through a Gi/Go-dependent coupling to adenylyl cyclase (2). Stimulation of 2- adrenergic receptors... stimulation. Nevertheless, another mechanism of regulation of iPLA2 by 2-adrenergic receptor cannot... ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
10 Nature Macmillan Publishers Ltd 1998 letters to nature
 

Summary:  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Stimulation of 2-adrenergic receptors on the cell surface by ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
11 213Commentary Introduction
 

Summary:  (Shenoy et al., 2001; Wang et al., 2003a). Agonist stimulation of 2-adrenergic receptors induces... ). Moreover, stimulation of 2-adrenergic receptors in HEK 293, HeLa and COS-7 cells significantly increases... with I B (Luan ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
12 cell biochemistry and function Cell Biochem Funct 2001; 19: 143152.
 

Summary:  frog, Rana sylvatica: the b2-adrenergic receptor and calcium transport systems in control, frozen... fractions, freezing effected an 88% decrease in b2-adrenergic receptor expression but was without effect... on the calcium pump; while thawing resulted in a recovery ...

  

Source: Storey, Kenneth B. - Departments of Biology & Chemistry, Carleton University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
13 Constitutive Activity of a Chimeric D2/D1 Dopamine Receptor LAURA B. KOZELL and KIM A. NEVE
 

Summary:  -adrenergic receptors to the amino acid resi- due found in the homologous domain of the 2-adrenergic receptor... receptor mutant with 2-adrenergic receptor sequence re- stored function to the mutant ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
14 2C-Adrenergic Receptors Exhibit Enhanced Surface Expression and Signaling upon Association with
 

Summary:  - and 2- Adrenergic receptor constructs were kindly provided by Robert Lefkowitz (Duke University Medical... ). 2C- and 2-Adrenergic Receptor Association 975 #12;Assays of ERK Activation. Cells grown on 12-well... - and ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
15 -Adrenergic Receptor Subtype-Specific Signaling in Cardiac Myocytes from 1 and 2 Adrenoceptor Knockout Mice
 

Summary:  in the pathogenesis of cardio- myopathy. Both 1 and 2 adrenergic receptors are expressed in human and murine hearts... of the beta2 adrenergic receptor gene. J Biol Chem 274:16694­16700. Communal C, Colucci WS and Singh K (2000... :2210­2212. Daaka Y, Luttrell LM ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
16 Topology of Class A G Protein-Coupled Receptors: Insights Gained from Crystal Structures of Rhodopsins,
 

Summary:  2,Ala33-Gln39, Arg239-Arg243,Ala272- Met283,Pro360-Leu367 Cyanopindolol Human2-adrenergic receptor... chimeratoC-IIIloop Human2-adrenergic receptor 20083d4s2.80Å/P212121E122W,N187E... for the 2-adrenergic ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
17 This Review is part of a thematic series on Heterodimerization of Signaling Molecules, which includes the following Regulation of G ProteinCoupled Receptor Signaling by Scaffold Proteins
 

Summary:  -catenin,103 atrophin104 2-Adrenergic receptor NHERF-1/223 NHE3,29 ezrin,105 CFTR,24,106­108 PDGFR,109 Taz... 110 2-Adrenergic receptor AKAP79/25037­40 PKA, PKC, calcineurin36 Angiotensin AT1 receptor Jak251 STAT... receptor ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
18 PERSPECTIVE Novel Features of G Protein-Coupled Receptor Kinase 4
 

Summary:  as a clathrin adaptor in endocytosis of the 2-adrenergic receptor. Nature (Lond) 383:447­450. Novel Features... -coupled receptor kinase family that phosphorylate the 2-adrenergic receptor facilitate sequestra- tion... , Codina J, and Lefkowitz RJ ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
19 insight review articles 206 NATURE | VOL 415 | 10 JANUARY 2002 | www.nature.com
 

Summary:  for the clustering of 2-adrenergic receptor into clathrin-coated pits. J. Biol. Chem. 275, 23120­23126 (2000). 7. De... . et al. -arrestin-dependent formation of 2 adrenergic receptor­Src protein kinase complexes. Science... . Regulation of ...

  

Source: Akabas, Myles - Department of Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
20 Copyright C Blackwell Munksgaard 2002 Traffic 2002; 3: 866877
 

Summary:  with the beta-2 adrenergic receptor (14­16), the angiotensin II receptor (17), the N-for- myl peptide receptor... with that of a number of other receptors, including the beta-2 adrenergic (37) and opioid ...

  

Source: Bourne, Henry - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine


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21 ACCELERATED COMMUNICATION Activation of Type II Adenylate Cyclase by D2 and D4 but Not
 

Summary:  of ACII in HEK 293 cells (9). D2 dopaminergic and 2-adrenergic receptors are among the Gi... -adrenergic receptor stimulates ACII in the absence of constitutively active s-Q227L. It has been suggested... that the ability of the ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
22 PERSPECTIVE New Determinants of Receptor-Effector Coupling: Trafficking
 

Summary:  of caveolae-related GPCR translocation, including cardiac 2-adrenergic and A1 adenosine receptors that move... out of caveolin-rich membranes upon agonist ex- posure and, in the case of 2-adrenergic receptors... signaling pathway. For example, cardiac ...

  

Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center

 

Collection: Biology and Medicine

 
23 A Dominant-Negative Human Growth Hormone-Releasing Hormone (GHRH) Receptor Splice Variant
 

Summary:  ), and the 2-adrenergic receptor (60, 68). In other examples, ligand binding appears to decrease the formation... that stimulates the synthesis and secretion of GH from pituitary somatotroph cells. The GHRH receptor is a seven... gene, which in turn stimulates the ...

  

Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
24 Olfactory receptor trafficking to the plasma membrane C. F. Bush and R. A. Hall*
 

Summary:  . In these studies, the b2-adrenergic receptor and three types of purinergic receptor, the P2Y1, P2Y2, and adenosine... protein kinase pathway in a Gi/o-dependent manner, while M71 in complex with the b2-adrenergic receptor... of heterologous ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
25 PERSPECTIVE Double Feature at the Signalplex
 

Summary:  of the 2-adrenergic receptor by the insulin receptor, creating a potent feedback inhibitor of its tyrosine... -like growth factor 1 receptors, and RTK transactivation contrib- utes to AT1 receptor stimulation... receptor. Ang ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
26 The past two years have seen remarkable advances in the structural biology of G-protein-coupled receptors (GPCRs). Highlights have
 

Summary:  --the human 2 adrenergic receptor (2AR), the avian 1AR and the human A2A adenosine receptor--as well... .etal.Beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.J.Biol.Chem.281, 1261... . Rasmussen, S. ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
27 Heterodimerization of G Protein-Coupled Receptors: Specificity and Functional Significance
 

Summary:  ) Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy... receptor surface expression is driven by associ- ation with the beta2-adrenergic receptor. Proc Natl Acad... in the rate of ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
28 The past two years have seen remarkable advances in the structural biology of G-protein-coupled receptors (GPCRs). Highlights have
 

Summary:  --the human 2 adrenergic receptor (2AR), the avian 1AR and the human A2A adenosine receptor--as well... an inactive conformation of the beta 2-adrenergic receptor. Mol.Pharmacol. 45, 390­394 (1994). 4. Chidiac, P... by the ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
29 Annu. Rev. Physiol. 2006. 68:491505 doi: 10.1146/annurev.physiol.68.040104.131050
 

Summary:  the NHERF proteins and several G protein­coupled receptors such as the 2-adrenergic receptor, the -opioid... . TABLE 1 Hormone receptor targets of NHERF G protein­coupled receptors 2-adrenergic receptor ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
30 Special issue: Allosterism and Collateral Efficacy Conformational complexity of
 

Summary:  , primarily focusing on spectroscopic studies of purified human b2 adrenergic receptor. Introduction G... studies of the human b2 adrenergic receptor. Efficacy and conformational states Ligand efficacy... ) Chimeric ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
31 December 2004 Volume 4, Issue 6
 

Summary:  .P. Olfactory receptor surface expression is driven by association with the 2-adrenergic receptor. Proc. Natl... ., Marullo, S., and Bouvier, M. Homodimerization of the 2-adrenergic receptor as a prereq- uisite for cell... ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
32 Allosteric Modulation of 2-Adrenergic Receptor by Zn2 GAYATHRI SWAMINATH, JACQUELINE STEENHUIS, BRIAN KOBILKA, and TAE WEON LEE
 

Summary:  Allosteric Modulation of 2-Adrenergic Receptor by Zn2 GAYATHRI SWAMINATH, JACQUELINE STEENHUIS... the effect of Zn2 on the functional properties of the 2-adrenergic receptor ( 2AR). We found... function in vivo. The ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
33 Transductionofbiochemicalsignalsacross cellmembranes
 

Summary:  is the very same signaling outcome as from epinephrine stimulation of the b2-adrenergic receptor. The simplest... transmembrane (7TM) receptors. This 7TM pattern, first seen in sequences for rhodopsin and the b2-adrenergic... was first worked out ...

  

Source: Hendrickson, Wayne A. - Department of Biochemistry and Molecular Biophysics, Columbia University

 

Collection: Biology and Medicine

 
34 Copyright 2003 by Lipid Research, Inc. This article is available online at http://www.jlr.org Journal of Lipid Research Volume 44, 2003 655
 

Summary:  to be enriched in lipid rafts or caveolae. This includes 1- and 2-adrenergic receptors, adenosine A1 re- ceptors... - riched in lipid rafts, led to a greater enhancement of 1-adrenergic-stimulated activity than 2-adrenergic... of the ...

  

Source: Pike, Linda J. - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis

 

Collection: Biology and Medicine

 
35 ELSEVIER Neuroscience Letters 175 (1994) 166--170 NHROSClENCE
 

Summary:  to act at an a2-adrenergic receptor, only in the presence of an increased intracellular Ca2÷. Key words... a re- ceptor with characteristics of the ~2-adrenergic receptor. These observations are consistent... terminals. Since ...

  

Source: Guo, Ming - Brain Research Institute, University of California at Los Angeles

 

Collection: Biology and Medicine

 
36 1999 Macmillan Magazines Ltd 7. Carter, C. S. et al. Anterior cingulate cortex, error detection, and the on-line monitoring of
 

Summary:  ................................................................. Two functionally distinct a2-adrenergic receptors regulate sympathetic neurotransmission Lutz Hein... , blood vessels and kidney1 . a2-Adrenergic receptors are known to have a critical role in ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
37 JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION Vol. 24, No. 3, pp. 165205, 2004
 

Summary:  RECEPTORS AND G PROTEINS As receptors that stimulate adenylate cyclase, the D1-like receptors were assumed... , the ability of D1-like receptors to stimulate adenylate cyclase in virtually any cell line (2), together... functional and behavioral responses to D1 ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
38 Ligand Stabilization of the 2 Adrenergic Receptor: Effect of DTT on Receptor Conformation Monitored by Circular Dichroism and Fluorescence Spectroscopy
 

Summary:  Articles Ligand Stabilization of the 2 Adrenergic Receptor: Effect of DTT on Receptor Conformation... : Treatment of the 2 adrenergic receptor with the reducing agent dithiothreitol (DTT) is known to abolish... ) and intrinsic tryptophan ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
39 Brief Communication 409 Assembly of an A kinase-anchoring protein2-adrenergic receptor
 

Summary:  Brief Communication 409 Assembly of an A kinase-anchoring protein­2-adrenergic receptor complex... ­3]. Phosphorylation of the 2-adrenergic receptor (2-AR) by protein kinase A (PKA), in addition to uncoupling adenylate... of the ...

  

Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle

 

Collection: Biology and Medicine

 
40 ASSOCIATE EDITOR: DIANNE M. PEREZ The Significance of G Protein-Coupled Receptor
 

Summary:  receptor) (Drake et al., 2006), asthma ( 2-adrenergic receptor) (Kawakami et al., 2004), and strokes... crystallization and structural determination by X-ray diffraction methods of GPCRs, including the 2- adrenergic... (follicle- stimulating ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine


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41 Heterodimerization with 2-Adrenergic Receptors Promotes Surface Expression and Functional Activity of 1D-Adrenergic
 

Summary:  Heterodimerization with 2-Adrenergic Receptors Promotes Surface Expression and Functional Activity... medium 1D- and 2-Adrenergic Receptor Heterodimerization 17 #12;(Vector Laboratories (Burlingame, CA... ; P2Y, purinergic receptor. 1D- and ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
42 Biochem. J. (2001) 354, 485491 (Printed in Great Britain) 485 Tyr199 in transmembrane domain 5 of the 2-adrenergic receptor interacts
 

Summary:  of the 2-adrenergic receptor interacts directly with the pharmacophore of a unique fluorenone... . The affinity and efficacy of either mutant receptor Abbreviations used: 2AR, 2-adrenergic receptor; [125 I... Q-biogene, Carlsbad, CA, U.S.A.). ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
43 2009 EuropEan MolEcular Biology organization EMBo reports Vol 10 | no 1 | 2009 41 literaturereportliterature report
 

Summary:  to promote agonist-stimulated ubiquitin- ation of the 2-adrenergic receptor (Shenoy etal, 2008). -arrestin 2... , so-called because they were discovered as 2-adrenergic-receptor- binding proteins. the arrestin... in the process of receptor ...

  

Source: McMahon, Harvey - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
44 Opiate-induced Adenylyl Cyclase Superactivation Is Isozyme-specific*
 

Summary:  activates the endogenous 2-adrenergic receptors, but not with 1 M ionomycin or TPA (Fig. 1). Similarly, COS... cells that had been chronically treated with agonists of opioid, muscarinic, 2-adrenergic... -muscarinic or TSH receptor displayed an elevated level of cAMP ...

  

Source: Vogel, Zvi - Department of Neurobiology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
45 The structure of active opsin as a basis for identification of GPCR agonists by dynamic homology modelling and virtual screening assays
 

Summary:  and inverse agonists in structure-based computational ligand screening. Using the b2- adrenergic receptor (B2... of opsin [15] and most recently structural models of active conformations of the b2-adrenergic receptor (B2... an activated state of the ...

  

Source: Gerwert, Klaus - Fakultät für Biologie, Ruhr-Universität Bochum

 

Collection: Biology and Medicine

 
46 Dendritic Spines: hippocampus Wednesday, November 10, 2010
 

Summary:  + + + + + Some receptors (e.g. 2) can stimulate AND inhibit AC 9 AC species Wednesday, November 10, 2010 #12... Mg2+, Mn2+ + + + + Some receptors (e.g. 2) can stimulate AND inhibit AC 9 AC species Wednesday... , 2010 #12;2AR Merge+ISO Gs-GFP Internalized Gs-GFP does not colocalize with endocytosed ...

  

Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

 

Collection: Biology and Medicine

 
47 Conserved waters mediate structural and functional activation of family A (rhodopsin-like)
 

Summary:  , engineered A2A-adenosine, 1- and 2-adrenergic receptors, permits comparative analysis of features common... (13) and mutant 2-adrenergic receptor with Fab (14), mutant turkey 1-adrenergic receptor... (omitting the T4 lysozyme amino acid sequence ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
48 Mark Boterman Steven R.J.G. Smits
 

Summary:  demonstrates that homologous desensitization of the 2-adrenergic receptor can be enhanced by PKC activation... , and Lefkowitz RJ, Desensitization of the isolated beta 2- adrenergic receptor by beta-adrenergic receptor kinase... kinase and G ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
49 Glycosylation of b1-adrenergic receptors regulates receptor surface expression and dimerizationq
 

Summary:  A (Con A) is known to inhibit b2-adrenergic receptor internalization [15], but Con A regulation of b1AR... ), consistent with findings for Con A treatment of b2-adrenergic receptors [15]. Strikingly, however... the ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
50 P E R S P E C T I V E www.SCIENCESIGNALING.org 11 January 2011 Vol 4 Issue 155 pe1 1
 

Summary:  , Olfactory receptor surface expression is driven by association with the beta2-adrenergic receptor. Proc... -olfactogram responses induced by specific odorants (13). Furthermore, the stimulation of adrenergic receptors enhanc- es... and muscarinic ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
51 D2/D3 Dopamine Receptor Heterodimers Exhibit Unique Functional Properties*
 

Summary:  of 2-adrenergic and m3-muscarinic receptors (15); more recently, using a pharmacological approach, we... was stimulated by the addition of 1 M FS in the presence or absence of the indicated dopamine receptor ligands... receptors, together with AC-V (A) or VI (B). AC ...

  

Source: Vogel, Zvi - Department of Neurobiology, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
52 Activation of G ProteinCoupled Receptors
 

Summary:  . Lefkowitz's group went on to es- tablish an affinity purification scheme for the 2 adrenergic receptor... helix VI in the 2 adrenergic receptor (46). Upon closer examination, however, the data point to a more... . The kinetics of fluorescence quenching changes in the ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
53 ISSN: 1524-4571 Copyright 2005 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online
 

Summary:  , Balke CW, Lakatta EG, Cheng H. Enhanced G(i) signaling selectively negates beta2- adrenergic receptor... . A beta2 adrenergic receptor signaling complex assembled with the Ca2 channel Cav1.2. Science. 2001... , Ramussen R, Zera P, Menlove R, Shah P, Jamieson S, ...

  

Source: Kamp, Tim - Molecular and Cellular Pharmacology Training Program & Department of Physiology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
54 Proposed Master Thesis Projects SSV 2011/2011
 

Summary:  organization and dynamics of GPCRs and G proteins (e.g. 2 adrenergic receptor and Gs protein) we plan... is particularly interested in nanostructural organization of G protein-coupled receptors (GPCRs) and G proteins

  

Source: Radenovic, Aleksandra - Laboratory of Nanoscale Biology, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Physics

 
55 G protein-coupled receptors (GPCRs) are the largest family of transmembrane proteins in vertebrates and they
 

Summary:  as EBP50 and SLC9A3R1) and the 2 -adrenergic receptor (2 AR) promotes the rapid recycling of receptors... 's interaction with the receptor needs to be regulated by agonist stimulation, as agonist-induced Department... -mail: rhall@pharm.emory.edu doi:10.1038/nrm2803 ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
56 P2 receptor web: Complexity and fine-tuning Cinzia Volont a,, Susanna Amadio a
 

Summary:  form heterodimers (see later). Stimulation of the homomeric P2X7 receptor by ATP induces cell membrane... permeability, mainly to extracellular Ca2+ , stimulation of P2Y receptor subtypes has been associated primarily... stimulate Ca2+ uptake, whereas P2Y2 receptor ...

  

Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London

 

Collection: Biology and Medicine

 
57 Perspectives in Pharmacology Stoichiometry and Compartmentation in G Protein-Coupled
 

Summary:  adaptor in endocytosis of the beta2-adrenergic receptor. Nature (Lond) 383:447­450. Hildebrandt JD (1997... Chem 273: 18677­18680. Liggett SB (1999) Molecular and genetic basis of beta2-adrenergic receptor... overexpressing the beta ...

  

Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center

 

Collection: Biology and Medicine

 
58 N-Ethylmaleimide-Sensitive Factor Regulates 2 Adrenoceptor Trafficking and Signaling in Cardiomyocytes
 

Summary:  ://molpharm.aspetjournals.org. doi:10.1124/mol.107.037747. ABBREVIATIONS: 2AR, 2-adrenergic receptor; 1AR, 1-adrenergic receptor... 2- adrenergic receptor. Nature 401:286­290. Cong M, Perry SJ, Hu LA, Hanson PI, Claing A... , and Lefkowitz RJ ...

  

Source: Xiang, Kevin Y. - Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign

 

Collection: Biology and Medicine

 
59 General introduction Definition of Asthma
 

Summary:  -studied bronchodilators are 2-agonists, which can activate 2-adrenergic receptors on airway smooth muscle (see paragraph... these two classes of drugs have complementary and synergistic effects [88]. The expression of 2-adrenergic... of the parasympathetic nervous system, leads to airway ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
60 Regulation of Adenylyl Cyclase Isozymes on Acute and Chronic Activation of Inhibitory Receptors
 

Summary:  of these inhibitory receptors (e.g., -, -, and -opioid; 2-adrenergic; somatostatin) are chronically activated... :1075­1082. Jones SB and Bylund DB (1988) Characterization and possible mechanisms of 2-adrenergic receptor... (10 M) of the nonselective dopaminergic ...

  

Source: Vogel, Zvi - Department of Neurobiology, Weizmann Institute of Science

 

Collection: Biology and Medicine


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61 The Endocytosis-Linked Protein Dynamin Associates with Caveolin-1 and Is Tyrosine Phosphorylated in
 

Summary:  (12), and the Src-mediated tyrosine phosphorylation of dynamin is re- quired for 2-adrenergic receptor... of dynamin is required for 2-adrenergic receptor internalization and mitogen-activated protein kinase... shown that EGF stimulation of mu- ...

  

Source: Bertics, Paul J. - Molecular and Cellular Pharmacology Training Program & Department of Biomolecular Chemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
62 Proc. Natl. Acad. Sci. USA Vol. 95, pp. 84968501, July 1998
 

Summary:  in the 2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator... of the 2-adrenergic receptor and plays a role in adrenergic regulation of Na H exchange. NHERF contains two... includes a number of transmem- ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
63 PERSPECTIVE Agonist Binding: A Multistep Process
 

Summary:  characterized experimental system, the 2 adrenergic receptor ( 2AR). They provide ev- idence for the existence... ., ABBREVIATIONS: GPCR, G protein-coupled receptor; 2AR, 2-adrenergic receptor. 0026-895X/04... distinct conformations in the G ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
64 Phosphorylation of the -Opioid Receptor at Tyrosine 166 (Tyr3.51) in the DRY Motif Reduces Agonist EfficacyS
 

Summary:  of the aspartic acid (Asp3.49) of the 2-adrenergic receptor results in structural instability of the receptor... -stabilized conformational states of the 2-adrenergic receptor has shown that agonist-induced changes include conformational... , and ...

  

Source: Bruchas, Michael R. - Department of Anesthesiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
65 Direct and Differential Interaction of -Arrestins with the Intracellular Domains of Different Opioid Receptors
 

Summary:  dependence and receptor specificity of -arrestin and arrestin in the 2-adrenergic receptor and rhodopsin... stimulation of the membrane receptors known as - (DOR), - (MOR), and - (KOR) opioid receptors, as demonstrated... , the reduced ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
66 Oligomeric forms of G protein-coupled receptors (GPCRs)
 

Summary:  found in crystals of engineered human b2-adrenergic receptor [29] and an engineered human A2A adenosine... including the b2-adrenergic receptor [32] and rhodop- sin [33,34] (Fig. 2A). However, if such monomeric... -resolution crystal structure of an engineered human ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
67 Interaction of Serotonin 5-Hydroxytryptamine Type 2C Receptors with PDZ10 of the Multi-PDZ Domain Protein MUPP1*
 

Summary:  /discs large/ZO-1) domain-containing proteins. The best investigated example is the 2-adrenergic receptor... with the 2-adrenergic receptor is me- diated via binding of the first PDZ domain of NHERF to the extreme C... terminus of the ...

  

Source: Lübbert, Hermann - Fakultät für Biologie, Ruhr-Universität Bochum

 

Collection: Biology and Medicine

 
68 Erythrocyte G ProteinCoupled Receptor Signaling in
 

Summary:  the erythrocyte 2-adrenergic receptor and hetero- trimeric guanine nucleotide­binding protein (G s) regulated... . Thus, signaling via the erythrocyte 2-adrenergic receptor and G s may regulate malarial infection... assay (2). P. berghei and ...

  

Source: Lomasney, Jon - Departments of Pathology & Pharmacology, Northwestern University

 

Collection: Biology and Medicine

 
69 antiosteogenic (it reduces bone mass). The finding led to speculation that increased
 

Summary:  then stimulates 2-adrenergic receptors on osteoblasts (bone-forming cells... and high bone mass; drugs that stimulate -adrenergic receptors do not affect the body fat of these mice... pro- opiomelanocortin, the precursor of - ...

  

Source: Nauwelaerts, Sandra - Department of Biology, Universiteit Antwerpen

 

Collection: Biology and Medicine

 
70 Structure-based discovery of 2-adrenergic receptor ligands
 

Summary:  Structure-based discovery of 2-adrenergic receptor ligands Peter Kolba,1 , Daniel M. Rosenbaumb,1... of the 2-adrenergic receptor offers an opportunity to investigate the advantages and limitations inherent... million commercially available, ``lead-like'' mol- ecules ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
71 The EMBO Journal Vol.16 No.22 pp.67376747, 1997 Agonists induce conformational changes in
 

Summary:  2-adrenergic receptor: purification and characterization. Biochemistry, 23, 4510­4518. Bouvier,M. et... al. (1989) Two distinct pathways for cAMP-mediated down-regulation of the 2-adrenergic receptor. J... purified ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
72 REVIEW ARTICLE Chemokine receptors and other G protein-coupled receptors
 

Summary:  of invertebrate rhodopsin, b1-adrenergic and b2-adrenergic receptors and the A2A-adenosine receptor have been... -adrenergic and b2-adrenergic receptors, and most recently, the structure of the A2A adenosine receptor [26... ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
73 Contribution of Serine Residues to Constitutive and Agonist-Induced Signaling via the D2S Dopamine Receptor: Evidence
 

Summary:  to the binding of agonists. Data obtained using mutants of the 2-adrenergic receptor lacking individual TM5... AMP accumulation via the endogenous 2-adrenergic receptors was measured in intact cells. Cells were plated... ) Contribution of ligand structure to activation ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
74 Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR
 

Summary:  concen- trations of an agonist, b2-adrenergic receptors (b2-ARs) signal through Gas to activate... ). For the Gs-coupled b2-adrenergic receptors (b2-ARs), c-Src has been shown to act downstream of Gs to mediate... ­25265 Daaka Y, Luttrell LM, Lefkowitz RJ (1997) ...

  

Source: Xiang, Kevin Y. - Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign

 

Collection: Biology and Medicine

 
75 Nederlandse samenvatting Nederlandse samenvatting
 

Summary:  voor een verminderde werking van 2-agonisten is heterologe desensitisatie van de 2-adrenerge receptor... acetylcholine, betrokken zou kunnen zijn bij de verminderde 2-adrenerge receptor functie in luchtweg gladde... receptor te desensitiseren, ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
76 Rijksuniversiteit Groningen Heterologous amplification of homologous
 

Summary:  these two classes of drugs have complementary and synergistic effects [88]. The expression of 2-adrenergic... of the parasympathetic nervous system, leads to airway smooth muscle contraction upon muscarinic receptor stimulation... , and is mediated by agonist-induced IP3 production and subsequent ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
77 Identification of Binding Domains of the Growth Hormone-Releasing
 

Summary:  of the GHRH receptor (VNGC and SNGC) bound GHRH and stimulated cAMP accumu- lation after GHRH treatment... -binding ability of the full-length GHRH receptor when coexpressed with it. GHRH treatment did not stimulate c... of the GHRH receptor, bound GHRH and stimulated ...

  

Source: Mayo, Kelly E. - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
78 An aplysia dopamine1-like receptor: molecular and functional characterization
 

Summary:  al. 2003). D1-like receptors stimulate adenylyl cyclase and phosphatidylinositol metabolism, whereas... californica. The Apdop1 receptor is a D1-like dopamine receptor because it stimulates adenylyl cyclase after... of the Apdop1 receptor The rank order of potency of ...

  

Source: Byrne, John H. - Department of Neurobiology and Anatomy, University of Texas Medical School at Houston

 

Collection: Biology and Medicine

 
79 The Effect of pH on 2 Adrenoceptor Function EVIDENCE FOR PROTONATION-DEPENDENT ACTIVATION*
 

Summary:  activation for the 2 adrenergic receptor ( 2AR). The rate of agonist-induced change in the fluorescence... for GPCR activation, we have applied fluo- rescent spectroscopic techniques to the 2 adrenergic receptor... )ethylenediamine; G protein, GTP-binding protein; ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
80 Dynamic Complexes of 2-Adrenergic Receptors with Protein Kinases and Phosphatases and the Role of Gravin*
 

Summary:  Dynamic Complexes of 2-Adrenergic Receptors with Protein Kinases and Phosphatases and the Role... -pro- tein-linked receptor kinase family, like the -adrenergic recep- tor kinase. 2-Adrenergic receptors ( 2... ; 2AR, ...

  

Source: Scott, John D. - Department of Pharmacology, University of Washington at Seattle

 

Collection: Biology and Medicine


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81 ISSN: 1524-4571 Copyright 2006 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online
 

Summary:  ). This is consistent with the previous notion that IGF-1 receptor tyrosine kinase stimulation acti- vates Akt via PI3K... of the 2-adrenergic/cAMP/PKA regulation of cardiac contractile responses has previously been identified.11... for the regulation of LTCCs by ...

  

Source: Kamp, Tim - Molecular and Cellular Pharmacology Training Program & Department of Physiology, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
82 Identification of G Protein-Coupled Receptor Kinase 2 Phosphorylation Sites Responsible for Agonist-Stimulated
 

Summary:  , be- ta-2 adrenergic receptor, C5a anaphylatoxin receptor, and alpha-1B adrenergic receptor (Ohguro et... Identification of G Protein-Coupled Receptor Kinase 2 Phosphorylation Sites Responsible for Agonist-Stimulated... caused 80 to 100% loss of ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
83 Accelerated Communication Selective Enhancement of -Adrenergic Receptor Signaling by
 

Summary:  with stimulatory agents to determine the ability of musca- rinic cholinergic receptors to inhibit stimulated AC... ) Dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac... ) Increased expression of adenylyl cyclase type VI proportionately increases ...

  

Source: Ostrom, Rennolds - Department of Pharmacology, University of Tennessee Health Science Center

 

Collection: Biology and Medicine

 
84 Respiration Physiology 129 (2001) 2535 Respiratory plasticity: differential actions of continuous and
 

Summary:  -adrenergic receptors and leading to LTD. The location of the relevant a2-adrenergic recep- tors is not known... ). Thus, activation of a2-adrenergic receptors on or near brainstem neurons involved in respira- tory... , ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
85 -Arrestin Differentially Regulates the Chemokine Receptor CXCR4-mediated Signaling and Receptor Internalization, and This
 

Summary:  of CXCR4. The classical mechanism of signal transduction is based on the work of the 2-adrenergic receptor... important roles in the desensi- tization and internalization of the 2-adrenergic receptor and receptor... activation, as in the well ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
86 Current Topics Oligomerization of G Protein-Coupled Receptors: Past, Present, and Future
 

Summary:  (reviewed in ref 108). For example, mutants of the 2 adrenergic receptor (109), the D2 dopamine receptor... of oligomerization by mutating the putative dimerization motif of the 2 adrenergic receptor and the R-factor ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
87 Development/Plasticity/Repair Norepinephrine Directly Activates Adult Hippocampal
 

Summary:  receptor antagonist, had no effect ( p 0.05; Bonferroni post hoc test), whereas the 2-adrenergic receptor... population, whereas 1- and 2-adrenergic receptors were expressed predominantly in the Hes5-negative... population (Fig. 6C). A small ...

  

Source: Vaidya, Vidita - Department of Biological Sciences, Tata Institute of Fundamental Research

 

Collection: Biology and Medicine

 
88 Supporting Information Angel et al. 10.1073/pnas.0903545106
 

Summary:  ), mutant 2-adrenergic receptor (2), squid rhodopsin (3), bovine rhodopsin (4), and mutant A2A... structures of squid rhodopsin (A) and mutant 2-adrenergic receptor (B). Waters are positioned... of G-coupled protein receptors (GPCRs). Amino acid ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
89 Identification of Novel G Protein-Coupled Receptor-Interacting Proteins. Richard T. Premont
 

Summary:  ), the interaction of the Na+H+ exchanger regulatory factor with the 2-adrenergic receptor (15), the interaction... - adrenergic receptor (17), and the interaction of 14-3-3 proteins with the 2-adrenergic receptors (18). Here... . For the human 1- ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
90 Mass Spectrometric Analysis of Agonist Effects on Posttranslational Modifications of the -2 Adrenoceptor in Mammalian Cells
 

Summary:  , University of California. | Stanford University. 1 Abbreviations: B2AR, -2 adrenergic receptor; GPCR, G... -coupled receptor kinase phospho- rylation sites in the human beta2-adrenergic receptor, J. Biol. Chem. 271, 13796... ., Friedman, J., ...

  

Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University

 

Collection: Biology and Medicine

 
91 C-terminal domains within human MT1 and MT2 melatonin receptors are involved in internalization processes
 

Summary:  , Bouvier M. Palmitoylation of the human b2-adrenergic receptor. Mutation of Cys 341 in the carboxy tail... C-terminal domains within human MT1 and MT2 melatonin receptors are involved in internalization... effects via G-protein-coupled melatonin receptors, MT1 and MT2 [2, 3]; however, it ...

  

Source: Pollock, John Archie - Department of Biological Sciences, Duquesne University

 

Collection: Biology and Medicine

 
92 b-Arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-jB
 

Summary:  that the b-arrestin2 phosphory- lation is critical. Moreover, stimulation of b2-adrenergic receptors... 2-Adrenergic receptor antagonist accelerates skin b-arrestinier recovery and reduces epidermal... of b-arrestin2 regulates its function in ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
93 In vitro and in vivo impairment of 2-2-2-2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue.
 

Summary:  In vitro and in vivo impairment of 2-2-2-2-adrenergic receptor-dependent antilipolysis by fatty... as described previously [7]. The 2-adrenergic receptors were identified with the selective antagonist... results, showed that BrPal-treatment had no influence on ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
94 2011NatureAmerica,Inc.Allrightsreserved. nature CHeMICaL BIOLOGY | AdvAnce online publicAtion | www.nature.com/naturechemicalbiology 1
 

Summary:  . The template for the homology model was the 2-adrenergic receptor, and one might predict that the screened... a large number of decoys as a criterion of model accuracy26,30,31 . The 1- and 2-adrenergic receptor... activity against ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
95 Preferential Interaction between the Dopamine D2 Receptor and Arrestin2 in Neostriatal Neurons
 

Summary:  desensitization, best characterized for the 2-adrenergic receptor, has been developed in which the agonist... loop of 2-adrenergic receptors determines subtype specificity of arrestin interaction. J Biol Chem 277... -fluorescent pro- tein-tagged D2 ...

  

Source: Neve, Kim A. - Department of Behavioral Neuroscience, Oregon Health and Science University

 

Collection: Biology and Medicine

 
96 Imaging G proteincoupled receptor islands Paul S-H Park & Krzysztof Palczewski
 

Summary:  optical microscopy has been used to study the organization of 1- and 2-adrenergic receptors in cardiac... stimulation of fluores- cently labeled receptor clusters produced no change in fluorescence intensity... Imaging G protein­coupled receptor islands Paul S-H Park ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
97 MOLECULAR AND CELLULAR BIOLOGY, 0270-7306/00/$04.00 0
 

Summary:  by stimulation of the 2-adrenergic receptor, a known cellular binding partner for NHERF. These findings reveal... described an interaction between the CT of the 2-adrenergic receptor ( 2AR) and an intracellular protein... and ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
98 1-Adrenergic Receptor Association with PSD-95 INHIBITION OF RECEPTOR INTERNALIZATION AND FACILITATION OF 1-ADRENERGIC RECEPTOR
 

Summary:  AR, 2-adrenergic receptor; 3AR, 3-adrenergic receptor; FITC, fluorescein isothiocyanate; HRP... are known to be regulated by 1AR stimulation. -Adrenergic receptors ( 1AR, 2AR, and 3AR)1 are hepta- helical... stimulation promotes LTP induction is ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
99 Heterodimerization of 2A-and 1-Adrenergic Receptors* Received for publication, August 5, 2002, and in revised form, December 23, 2002
 

Summary:  , Atlanta, Georgia 30322 - and 2­adrenergic receptors are known to exhibit substantial cross-talk and mutual... receptors they express. Because - and 2-adrenergic receptors couple to G proteins with opposing actions... - internalize from the cell ...

  

Source: Hall, Randy A - Department of Pharmacology, Emory University

 

Collection: Biology and Medicine

 
100 Introduction Chapter 1 1 Introduction
 

Summary:  the affinity for the 2-adrenergic receptor. For this compound, the considerable affinity can be argued... low affinity for spiperone. In contrast, spiperone sensitive stimulation of 5-HT2 receptors... -94 : it stimulated only those receptors ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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