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Sample search results for: abc transporter mutation

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1 PROTEIN INTERACTIONS AND DISEASE PHENOTYPES IN THE ABC TRANSPORTER SUPERFAMILY
 

Summary:  residue level is not known. Point mutations at interfaces can affect the function of ABC transporters... (Figure 3, Discussion). 3.2. Disease associated mutations at ABC transporter interfaces We found a total... interfaces. This indicates that a majority of disease- ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
2 ABC transporters ABC transporter architecture and regulatory roles of
 

Summary:  experiments performed with the oligopeptide ABC transporter (Doeven et al., 2004). Mutational and suppressor... ABC transporters 9 Chapter 2 ABC transporter architecture and regulatory roles of accessory domains... of the architecture of ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
3 2000 Macmillan Magazines Ltd NATURE CELL BIOLOGY | VOL 2 | JULY 2000 | www.nature.com/ncb 399
 

Summary:  -binding-cassette transporter 1 (ABC1) has been implicated in processes related to membrane-lipid turnover. Here, using in vivo... -of-function experiments. Analysis of mice harbouring a null mutation in the ABC1 gene and of HeLa cells transfected... of the regulatory domain of the ...

  

Source: Institut de Biologie Physico-Chimique CNRS, Physico-Chimie Moléculaire des Membranes Biologiques

 

Collection: Chemistry ; Biology and Medicine

 
4 Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a
 

Summary:  (Fig. 1D). ABCE1 with mutations in NBD1 (E238Q and H269A) showed only 30­50% activity compared to wild... -type ABCE1 as a conse- quence of the inactivation of site I. Strikingly, mutations in NBD2 (E485Q and H518A... , Lewinson O (2009) ABC transporters: The power to ...

  

Source: Bedwell, David M. - Department of Microbiology, University of Alabama at Birmingham

 

Collection: Biology and Medicine

 
5 Genome Biology 2004, 5:R15 commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation
 

Summary:  commentreviewsreportsdepositedresearchrefereedresearchinteractionsinformation Open Access2004Shepset al.Volume 5, Issue 3, Article R15Research The ABC transporter gene family... purpose, provided this notice is preserved along with the article's original URL. The ABC transporter gene... severalgene families ...

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
6 Functional hot spots in human ATP-binding cassette transporter
 

Summary:  Transporters #12;Mutations in this motif are associated with disease in seven human ABC transporters: CFTR... communication network between the NBD and the transmembrane helices of human ABC transporters. Mutations... . Predictions of the ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
7 Gene 221 (1998) 117125 Isolation of an Arabidopsis thaliana cDNA by complementation of a yeast
 

Summary:  of the S. cerevisiae mutation abc1::LEU2 bySection 2.2). About 250 000 uracil prototroph trans- the A... -related genes appear not to be essential fordeficiency due to the abc1-null mutation in S. cerevisiae... Gene 221 (1998) 117­125 Isolation of an Arabidopsis thaliana cDNA by complementation of a yeast ...

  

Source: Hamel, Patrice - Department of Plant Cellular and Molecular Biology, Ohio State University; Meier, Iris - Department of Plant Cellular and Molecular Biology, Ohio State University

 

Collection: Biology and Medicine

 
8 Response to "PREDICTABLE DIFFICULTY OR DIFFICULTY TO PREDICT" by Tams Arnyi, Krisztina Fulop, Orsolya Symmons, Viola Pomozi, and Andrs Vradi
 

Summary:  automated bioinformatics tool, we recently classified 40 point mutations in ABC transporters as "neutral... simultaneously with a nonsense mutation (Y1069X) in the analyzed form of the transporter.9 Therefore, we do... mutations, with a different impact on a ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
9 Summary and concluding remarks Introduction
 

Summary:  (ABC) transporters MsbA, a lipid efflux system that was crystallized in three conformations... of a complete transporter is available yet, The abbreviations used are: ABC, ATP-binding cassette; ECD... by ABC transporters, in particular that of the oligopeptide ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
10 Mapping of Interdomain Interfaces Required for the Functional Architecture of Yor1p, a Eukaryotic ATP-binding
 

Summary:  fundamental physiological processes. Mutations in a single ABC transporter, the cystic fibrosis transmembrane... with specific alleles of aberrant ABC transporters. Further- more, the capacity of the suppressing mutations... ATP-binding Cassette ...

  

Source: Miller, Liz - Department of Biological Sciences, Columbia University

 

Collection: Biology and Medicine

 
11 Copyright 2007 by the Genetics Society of America DOI: 10.1534/genetics.106.066720
 

Summary:  Accepted for publication December 24, 2006 ABSTRACT ABC transporters constitute one of the largest gene... -binding cassette (ABC) transporter proteins con- stitute one of the largest protein families in both prokaryotes... acids into the cell. In eukaryotes, the majority of ABC ...

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
12 Expression Analysis of ABC Transporters Reveals Differential Functions of Tandemly Duplicated Genes in
 

Summary:  reticulum, peroxisomes, and mito- chondria.1,2 Mutation of ABC transporters can result in various diseases... Expression Analysis of ABC Transporters Reveals Differential Functions of Tandemly Duplicated Genes... , BC Canada V5Z 1L6 We have previously identified 60 predicted ...

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
13 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Sept. 2003, p. 27252731 Vol. 47, No. 9 0066-4804/03/$08.00 0 DOI: 10.1128/AAC.47.9.27252731.2003
 

Summary:  the cytochrome b mutations and a deletion of the ABC transporter genes, allowing the drug to bypass the weakened... transporters. The mitochondrial genome carrying the atovaquone resistance mutations was transferred into strain... . The resulting strains combined atovaquone ...

  

Source: Trumpower, Bernard L. - Department of Biochemistry, Dartmouth College

 

Collection: Biology and Medicine

 
14 JOURNAL OF BACTERIOLOGY, 0021-9193/99/$04.00 0
 

Summary:  transporter BtuCD. New mutations (btuF) are described that affect inner-membrane transport. The BtuF protein... and internal adenosylation (13, 24). If the btuF mutation impairs cobalamin transport, it should also impair... -membrane transport; this initial ...

  

Source: California at Davis, University of - Center for Genetics and Development, Roth Laboratory

 

Collection: Biology and Medicine ; Biotechnology

 
15 Intragenic Suppressing Mutations Correct the Folding and Intracellular Traffic of Misfolded Mutants of Yor1p, a
 

Summary:  of a loss-of-function disease related to ABC transporter func- tion: CF-causing mutations are associated... (s) induced by disease-related mutations on the quaternary structure of ABC transporters may provide insight... -domain interfaces can be generally applicable to ...

  

Source: Miller, Liz - Department of Biological Sciences, Columbia University

 

Collection: Biology and Medicine

 
16 Cell, Vol. 93, 951960, June 12, 1998, Copyright 1998 by Cell Press The C. elegans Cell Corpse
 

Summary:  Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters In the nematode Caenorhabditis elegans... protein has sequence similarity to and are readily distinguishable using Nomarski opticsABC transporters... . Like CED-7, the mammalian ABC transporter show ...

  

Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
17 [CANCER RESEARCH 61, 66356639, September 15, 2001] Advances in Brief
 

Summary:  ; this is one of the first examples of an ABC transporter exhibiting a gain of function mutation upon selection... in sitosterolemia caused by mutations in adjacent ABC transporters. Science (Wash. DC), 290: 1771­1775, 2000. 8. Lee... . Mutations ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
18 Function of prokaryotic and eukaryotic ABC proteins in lipid transport Antje Pohla,b
 

Summary:  of the ABC protein families A, B, C, D and G are mutated in a number of lipid transport and metabolism... Review Function of prokaryotic and eukaryotic ABC proteins in lipid transport Antje Pohla... and further transport to specific sites. Additionally, lipid ...

  

Source: Institut de Biologie Physico-Chimique CNRS, Physico-Chimie Moléculaire des Membranes Biologiques

 

Collection: Chemistry ; Biology and Medicine

 
19 General Introduction Chapter 1: General Introduction
 

Summary:  -dependent primary transporters 21 4.1: The ABC superfamily portrait 21 4.2: The substrate-binding domain 22 4... -dependent transporters 27 5.1: Substrate binding 28 5.2: Functional interactions in the binding protein-dependent 30 ABC... -hydrolysis (Fig. 1c). These proteins are members of the ATP-binding ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
20 Sugar Transport in (Hyper-)Thermophilic Archaea Sonja M. Koning, Sonja-Verena Albers, Wil N. Konings and Arnold J. M.
 

Summary:  at the expense of PEP; and iii) ATP binding cassette (ABC) transport, where the substrate is first bound... . Schematic overview of the different transport classes, namely secondary (A), PTS (B), and ABC (C). #12... ;Introduction 4 2.2. Binding protein dependent ABC- type ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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21 Homology Modeling of the Human Microsomal Glucose 6-Phosphate Transporter Explains the Mutations That Cause the Glycogen Storage Disease Type Ib
 

Summary:  by mutations in the glucose 6-phosphate transporter (G6PT) in the endoplasmic reticulum membrane in liver... to reduce or abolish the transporter's activity. However, the mechanisms by which these mutations impair... mutations (2, 3). Among them, the transport ...

  

Source: Wang, Da-Neng - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University

 

Collection: Biology and Medicine

 
22 10.1110/ps.051998406Access the most recent version at doi: 2006 15: 1597-1607Protein Sci.
 

Summary:  members of the ATP-binding cassette (ABC) transporter superfamily, including P-glycoprotein and the half-transporter... recognition and binding. Keywords: ABCG2; BCRP; ABC transporter; P-glycoprotein; [125 I... ]iodoarylazidoprazosin Mammalian ABC (ATP-binding ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
23 Chapter 1 An introduction to adenine nucleotidebinding proteins Adenosine triphosphate
 

Summary:  binding cassette (ABC) transport ATPases has been the focus of this thesis and these proteins... through ligandgated ion channels [16]. Transport ATPases The P, V and FATPases together with the ABC... of an electrochemical ion gradient [19]. The class of ABC ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
24 General introduction I. General features of cell volume control
 

Summary:  to an osmotic upshift are substrate-binding protein-dependent ABC transporters, which use ATP as source... of the system for another transport cycle. The osmoregulated ABC transporters belong to the OTCN family (26... biochemical evidence is not available, the osmoregulated ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
25 Stuctural stability and domain organization Structural Stability of GlcV, the Nucleotide Binding
 

Summary:  Domain of the Glucose ABC Transporter of Sulfolobus solfataricus Monika G. Pretz, Chris van der Does... binding domain of the ABC type glucose transporter of the hyperthermoacidophile Sulfolobus solfataricus... ATP-binding cassette (ABC) transporters drive the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
26 Summary and concluding remarks Thermophilic organisms thrive at relatively high temperatures in geothermally heated regions such
 

Summary:  drugs, vitamins, lipids and so forth. Mutations in genes encoding for ABC transporters can cause... of transport ATPases studied in this thesis is the ATP-binding cassette (ABC) Transporters. ABC transporters... or cystic ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
27 Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression
 

Summary:  transporters in the ATP Binding Cassette (ABC) and Solute Carrier (SLC) superfamilies in 272 DNA samples from... for the transport of drugs and other xenobiotics. ABC transporters are efflux pumps that rely on ATP hydrolysis... to actively move substrates across biological membranes ...

  

Source: 

 

Collection: Biology and Medicine ; Biotechnology

 
28 Introduction General introduction
 

Summary:  , mutations of ABC transporter genes can result in severe diseases, while the classical multidrug resistance... others including ATPases of the ABC transporter superfamily, the F-ATPase superfamily or the motor... characteristics. We are going to focus on the group of thermophilic ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
29 Introduction to multidrug transporters, cellular resistance and lantibiotic production in Lactococcus lactis
 

Summary:  , and of the ABC transporter NisT in the lantibiotics secretion. #12;8 Introduction In Gram-positive bacteria... the cytoplasmic membrane. Many MDR transporters are members of the large ATP-binding cassette (ABC) superfamily (2... major characteristic of ABC-type ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
30 Mutation Systems Dana Angluin James Aspnes Raonne Barbosa Vargas
 

Summary:  , James Aspnes, Raonne Barbosa Vargas Mutation Systems #12;Fitness Pairs for abc ac Dana Angluin, James... Mutation Systems Dana Angluin James Aspnes Raonne Barbosa Vargas Department of Computer Science... Yale University LATA 2011 Dana Angluin, James Aspnes, Raonne Barbosa Vargas Mutation Systems #12

  

Source: Aspnes, James - Department of Computer Science, Yale University

 

Collection: Computer Technologies and Information Sciences

 
31 LmrCD is a major MDR transporter in Lactococcus lactis
 

Summary:  ) transporters, of which only four, i.e. the ABC transporters LmrA, LmrC and LmrD, and the major facilitator Lmr... and that binds to the promoter region of lmrCD. These results demonstrate that the heterodimeric MDR ABC-transporter... -Nodulation-cell Division family (RND), all secondary ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
32 Regulation of Manganese Uptake in Synechocystis 6803 by RfrA, a Member of a Novel Family of Proteins Containing a Repeated Five-Residues Domain
 

Summary:  affinity manganese transport system different from the more thoroughly characterized manganese ABC... : the ATP-binding cassette (ABC) transporters and the natural resistance-associated macrophage proteins... . The ABC transporter system (MntABC) ...

  

Source: Pakrasi, Himadri - Department of Biology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
33 doi: 10.1046/j.1529-8817.2003.00072.x Quantifying the Intragenic Distribution of Human
 

Summary:  , L. M. & Pedersen, P. L. (1997) Modeling of nucleotide binding domains of ABC transporter proteins... Mutations M. P. Miller1,3 , J. D. Parker1 , S. W. Rissing1 and S. Kumar1,2, 1 School of Life Sciences and 2... vary in their roles regarding overall gene function, the ability for a mutation in a gene ...

  

Source: Kumar, Sudhir - Department of Biology, Arizona State University

 

Collection: Biology and Medicine

 
34 Functional Rescue of a Misfolded Eukaryotic ATP-binding Cassette Transporter by Domain Replacement*S
 

Summary:  , The Johns Hopkins School of Medicine, Baltimore, Maryland 21205 ATP-binding cassette (ABC) transporters... ) of the yeast ABC transporter, Yor1p, perturbs interdomain asso- ciations, reduces functionality, and hinders... trans- porters by physically replacing dysfunctional domains. ATP-binding cassette ...

  

Source: Miller, Liz - Department of Biological Sciences, Columbia University

 

Collection: Biology and Medicine

 
35 Copyright 2002 by Lipid Research, Inc. 1610 Journal of Lipid Research Volume 43, 2002 This article is available online at http://www.jlr.org
 

Summary:  mutation on the function of the ABCA1 transporter, we engineered a construct harbouring the E89K mutation... . The presence of the WHAM mutation impairs physiological intracellular trafficking since most of the transporter... appears to be re- tained in the endoplasmic reticulum. ...

  

Source: Attie, Alan D. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
36 Structure and Dynamics of Large Biological Molecules: ATP-Binding Cassette (ABC) Transporters
 

Summary:  Structure and Dynamics of Large Biological Molecules: ATP-Binding Cassette (ABC) Transporters Jung... . ABC transporters are membrane proteins that actively transport substrates through lipid bilayers4... helices. Selective uptake and efflux by ABC ...

  

Source: Jones, R. O.- Institut für Festkörperforschung, Forschungszentrum Jülich

 

Collection: Materials Science

 
37 ABC transporters: Lessons from a bacterial oligopeptide uptake system
 

Summary:  experiments performed with the oligopeptide ABC transporter (Doeven et al., 2004). Mutational and suppressor... ABC transporters: Lessons from a bacterial oligopeptide uptake system Mark K. Doeven #12;Cover... by PrintPartners Ipskamp, Enschede #12;RIJKSUNIVERSITEIT GRONINGEN ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
38 ABC transporters: Lessons from a bacterial oligopeptide uptake system
 

Summary:  ABC transporters: Lessons from a bacterial oligopeptide uptake system Mark K. Doeven #12;Cover... by PrintPartners Ipskamp, Enschede #12;RIJKSUNIVERSITEIT GRONINGEN ABC transporters: Lessons from... A determines the selectivity of the oligopeptide ABC transporter 35 ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
39 CCoonnttrriibbuuttiioonn ooff GGllnnRR RReegguulloonn ttoo VViirruulleennccee Site-Specific Contributions of Glutamine-Dependent
 

Summary:  P, and glnQ, these included genes encoding transcriptional regulators (e.g., SPD0096, SPD1524), ABC-transporters... 0144 CAAX amino terminal protease family protein 4.0 SPD0148 SP0145 ABC transporter, substrate... ABC transporter 2.1 SPD0335 SP0368 cell wall surface anchor family protein ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
40 Copyright 2004 by the Genetics Society of America DOI: 10.1534/genetics.104.033266
 

Summary:  in the genes PDR1 and PDR3, which regulate the ABC transporters implicated in resistance to fluconazole... mutation in populations of Saccharomyces cerevisiae. Under conditions of low drug concentration, mutations... for a resistance mutation sooner than haploid populations. Experiments ...

  

Source: Anderson, James B. - Department of Ecology and Evolutionary Biology, University of Toronto

 

Collection: Environmental Sciences and Ecology


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41 Nederlandse samenvatting Nederlandse samenvatting voor genteresseerden buiten
 

Summary:  vakgebied Samenvatting ABC transporters zijn eiwitten die betrokken zijn bij de opname van voedingsstoffen... en uitscheiding van schadelijke stoffen in de biologische cel. Defecten in ABC transporters kunnen... bij de mens ernstige ziektes tot gevolg hebben. Te grote activiteit van ABC ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
42 Translocation of a thioether-bridged azurin peptide fragment via the Sec pathway in Lactococcus lactis
 

Summary:  residues stereo- and regioselectively to cysteines and NisT, the ABC transporter, translocates the modified... that are inefficiently transported via NisT. Appl Environ Microbiol. 2009 ;75:3800-2. #12;Chapter 6 78 Azurin... of the propeptides (226). When transport via NisT is impaired or is less efficient, ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
43 JOURNAL OF BACTERIOLOGY, Jan. 2006, p. 464468 Vol. 188, No. 2 0021-9193/06/$08.00 0 doi:10.1128/JB.188.2.464468.2006
 

Summary:  -nitrogenase activity when added to V-starved cells was about 3 10 9 M. The genes for an ABC-type vanadate transport... transport system that functioned in the vupB mutant. The vupABC genes belong to a family of putative metal... , and tungstate uptake is mediated by a specific ABC ...

  

Source: Thiel, Teresa - Department of Biology, University of Missouri-St. Louis

 

Collection: Biotechnology ; Biology and Medicine

 
44 Catalytic cycle of the oligopeptide ABC transporter Probing the catalytic cycle of the oligopeptide ABC
 

Summary:  Catalytic cycle of the oligopeptide ABC transporter 101 Chapter 7 Probing the catalytic cycle... of the oligopeptide ABC transporter by fluorescence correlation spectroscopy Mark K. Doeven, Geert van den Bogaart... for another catalytic cycle. Implications in terms of a general transport ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
45 Oligomerization of the Human ABC Transporter ABCG2: Evaluation of the Native Protein and Chimeric Dimers
 

Summary:  Oligomerization of the Human ABC Transporter ABCG2: Evaluation of the Native Protein and Chimeric... of the ATP binding cassette (ABC) transporter superfamily, is overexpressed in numerous multidrug... . Human ABCG2, also known as MXR/BCRP/ABCP, is a member of the ATP binding cassette ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
46 Bindosome assembly system Identification of a system required for the functional assembly of
 

Summary:  EF and basABC strains on arabinose and glucose is due to a reduced substrate transport activity, D-[14 C... of arabinose transporter. Finally, western blot analysis demonstrated that GlcV, the ATPase of the ABC glucose... levels of the different transporters. Figure5. Expression levels of ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
47 Summary and concluding remarks Summary and concluding remarks
 

Summary:  of cholesterol homeostasis in macrophages by different ABC-transporters, and the consequences for atherosclerotic... their transformation into foam cells. Several ABC- transporters facilitate the efflux of cholesterol from macrophages... to outside of the membrane. Several members - 120 - #12;Chapter 7 of the ...

  

Source: van den Brink, Jeroen - Leiden Institute of Physics, Universiteit Leiden

 

Collection: Physics

 
48 ABC and Model Selection Christoph Leuenberger
 

Summary:  (Watterson) FIGURE: Population mutation parameter = 4Nµ Christoph Leuenberger ABC and Model Selection #12... ABC and Model Selection Christoph Leuenberger Université de Fribourg, Switzerland Paris, June 26... , 2009 Christoph Leuenberger ABC and Model Selection #12;The Curse of Dimensionality Almost two ...

  

Source: Robert, Christian P. - Centre De Recherche en Mathématiques de la Décision, Université Paris-Dauphine

 

Collection: Mathematics

 
49 2009-taebc ABC-Clio ebooks collection 1203titles ISBN URL
 

Summary:  2009-taebc ABC-Clio ebooks collection 1203titles ISBN URL 1 Arts & Humanities Acquisitions... Bastian, Jeannette Allis Libraries Unlimited Ebooks 2003 http://ebooks.abc- clio.com/?isbn=9780313052378 2... Libraries Unlimited Ebooks 2007 http://ebooks.abc- clio.com/?isbn=9780313094521 3 Arts & Humanities

  

Source: Wu, Yih-Min - Department of Geosciences, National Taiwan University

 

Collection: Geosciences

 
50 Arch Microbiol (2008) 189:597604 DOI 10.1007/s00203-008-0356-8
 

Summary:  -arginine signal peptide · ABC transporter · Periplasmic binding protein · Outer membrane Introduction The Tat... across the cell membrane is driven by ABC transporters, usually comprising a periplasmic solute binding... show that for another ABC transporter, the ...

  

Source: Palmer, Tracy - Division of Molecular Microbiology, University of Dundee

 

Collection: Biology and Medicine

 
51 Quantifying the energetic interplay of RNA tertiary and secondary structure interactions
 

Summary:  of tertiary and secondary interactions in tP5abc. Point mutations predicted to destabilize the secondary... . In contrast to these data on tP5abc, the same point mutations in the context of the P4­P6 domain (of which P5... of P4­P6+ Mutations in the P5c stem affect ...

  

Source: Silverman, Scott K. - Department of Chemistry, University of Illinois at Urbana-Champaign

 

Collection: Chemistry ; Biology and Medicine

 
52 EFFLUX TRANSPORTERS: Newly Appreciated
 

Summary:  transporter proteins belonging to the adenosine triphosphate (ATP)-bindingcassette(ABC... EntAl SCiEnCE & tEChnology / JunE 1, 2008 #12;(hence, ABC transporters), and are present in all or- ganisms... . However, all of these chemicals can act on other types of ABC ...

  

Source: 

 

Collection: Environmental Sciences and Ecology

 
53 Applied Mathematics Letters 24 (2011) 12511256 Contents lists available at ScienceDirect
 

Summary:  to trigger the induction of ATP-Binding Cassette (ABC) transporters, responsible for the efflux of the drug... of CPT11-induced overexpression of ABC transporters. We then theoretically optimized exposure to CPT11... given as a single agent or combined either with ABC ...

  

Source: Clairambault, Jean - Biologie, Analyse Numérique, Géophysique Team, INRIA Paris-Rocquencourt

 

Collection: Biology and Medicine

 
54 Proton motive force-dependent Hoechst 33342-transport by the ABC transporter LmrA of Lactococcus lactis
 

Summary:  35 Chapter 3 Proton motive force-dependent Hoechst 33342-transport by the ABC transporter Lmr... constructed mutants of the adenosine triphosphate (ATP) binding cassette (ABC)-type MDR transporter Lmr... in the ABC signature motif with an LmrA-mediated Hoechst ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
55 Phenylalanine-508 mediates a cytoplasmicmembrane domain contact in the CFTR 3D structure crucial
 

Summary:  -binding cassette (ABC) transporter family, disrupts both its folding and function and causes most cystic fibrosis... biochemical studies of other features of this unique ABC ion channel. ABC transporter cystic fibrosis domain... -binding cassette (ABC) ...

  

Source: Dokholyan, Nikolay V. - Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill

 

Collection: Physics ; Biology and Medicine

 
56 BioMed Central Page 1 of 11
 

Summary:  author Abstract Background: ABC proteins constitute one of the largest families of transporters found... in all living organisms. In Arabidopsis thaliana, 120 genes encoding ABC transporters have been... are ABC transporters [6,7]. The ATP-binding cassette ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
57 INFECTION AND IMMUNITY, 0019-9567/99/$04.00 0
 

Summary:  polypeptides with extensive homology to the yfe ABC iron transport system of Yersinia pestis, as well as other... ABC transporters. The sitA gene encodes a putative periplasmic binding pro- tein, sitB encodes an ATP... typhimurium. This system belongs to the ABC family of ...

  

Source: Galan, Jorge E - Boyer Center for Molecular Medicine & Department of Cell Biology, Yale University

 

Collection: Biology and Medicine

 
58 General Discussion Chapter 6: General Discussion
 

Summary:  in uptake of organic anions, when the TeaABC system of Halomonas elongata was shown to transport... -dependent secondary transport... Although the binding protein-dependent secondary transporters were described in 1996... , to this day only a few these transporters have been functionally ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
59 Non-linear regression models for Approximate Bayesian Computation
 

Summary:  Non-linear regression models for Approximate Bayesian Computation (ABC) Michael Blum Olivier... François TIMC-IMAG, Faculty of Medicine U. Grenoble #12;Accept/Reject ABC methods suffer from the curse... of dimensionality ABC is wasteful. A typical usage may involve millions of simulations, and it retains only a few

  

Source: Robert, Christian P. - Centre De Recherche en Mathématiques de la Décision, Université Paris-Dauphine

 

Collection: Mathematics

 
60 Supplementary Methods, Results, Tables and Figures Systems metabolic engineering of Escherichia coli for L-
 

Summary:  C anaerobically inducible L-threonine transporter 1.70 a Transcriptome profiles of TH07 (pBRThrABC) were compared... @kaist.ac.kr 20 #12;- 2 - Supplementary Methods Strains and plasmids For the construction of pKKThrABC plasmid... fragment of pKK223-3 vector. The resulting plasmid, pKKThrABC, contains the ...

  

Source: Korea Advanced Institute of Science and Technology, Department of Chemical and Biomolecular Engineering, Metabolic & Biomolecular Engineering National Research Laboratory

 

Collection: Engineering ; Biotechnology


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61 JOURNAL OF BACTERIOLOGY, Apr. 2009, p. 24232430 Vol. 191, No. 8 0021-9193/09/$08.00 0 doi:10.1128/JB.01464-08
 

Summary:  - sors depend on this cooperative interaction to bind efficiently to DNA. A mutation of the lutABC operon... uncharacterized yvfV- yvfW-yvbY (herein renamed lutABC) operon, which is inferred to encode three iron... -lactate. Operons with high similarity to lutABC are present in the genomes of a variety of ...

  

Source: Losick, Richard M. - Department of Molecular and Cellular Biology, Harvard University

 

Collection: Biotechnology ; Biology and Medicine

 
62 JOURNAL OF BACTERIOLOGY, Apr. 2009, p. 24232430 Vol. 191, No. 8 0021-9193/09/$08.00 0 doi:10.1128/JB.01464-08
 

Summary:  - sors depend on this cooperative interaction to bind efficiently to DNA. A mutation of the lutABC operon... uncharacterized yvfV- yvfW-yvbY (herein renamed lutABC) operon, which is inferred to encode three iron... -lactate. Operons with high similarity to lutABC are present in the genomes of a variety of ...

  

Source: Losick, Richard M. - Department of Molecular and Cellular Biology, Harvard University

 

Collection: Biotechnology ; Biology and Medicine

 
63 ATP-binding cassette protein E is involved in gene transcription and translation in Caenorhabditis elegans
 

Summary:  and nucleus, and possibly as a nucleocytoplasmic transporter. In addition, RNAi data suggest that ABCE and NHR... Elsevier Inc. All rights reserved. Keywords: ABC transporter; ABCE; RNase L inhibitor; Caenorhabditis... of the largest protein families in both prokaryotes and eukaryotes. ...

  

Source: Baillie, David - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
64 Introduction General introduction
 

Summary:  . Furthermore, it includes genes encoding a dedicated ABC-transporter and an accessory protein (except... -binding cassette (ABC) transporters and their accessory proteins, or by the general sec-dependent secretory pathway... a specific transport system (Håvarstein et al., 1995; Franke et al., 1996). The ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
65 Mutation Detection with Next-Generation Resequencing through a Mediator Genome
 

Summary:  (figure 3). 752169 DNA polymerase I Bd0802 ATC ATt I I 807701 alkylphosphonate ABC transporter Bd0859 GGG... Mutation Detection with Next-Generation Resequencing through a Mediator Genome Omri Wurtzel1... the field of mutation analysis in bacteria. The genetic basis for phenotype alteration can be identified

  

Source: Sorek, Rotem - Department of Molecular Genetics, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
66 A Salt-Inducible Expression System for Production of Pediocin PA-1 Mutants.
 

Summary:  peptides have been exchanged or heterologous ABC-transport and processing systems have been directly used... CD and pABC2, we chose to make mutations in pedA in plasmid pABC2. Pediocin PA-1 mutants. To validate... with mutations in pedCD was reduced. A number of position-randomized ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
67 The ABC of ABC-transport in the hyperthermophilic
 

Summary:  The ABC of ABC-transport in the hyperthermophilic archaeon Pyrococcus furiosus #12;This work... ;RIJKSUNIVERSITEIT GRONINGEN The ABC of ABC-transport in the hyperthermophilic archaeon Pyrococcus furiosus... by an inducible, high-affinity ABC-transporter 25 Chapter 3 Biochemical evidence ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
68 doi:10.1006/scdb.2001.0250, available online at http://www.idealibrary.com on seminars in CELL & DEVELOPMENTAL BIOLOGY, Vol. 0, 2001: pp. 110
 

Summary:  cassette (ABC) superfamily of membrane transporters. This review focuses on the use of structure... -gp's that affect substrate specificity f aaa Mutation Regionb Sourcec Reference aa 78­97 EC 1 human MDR1 78 (ABC20... defined, may serve as the paradigm for many ABC ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
69 Copyright 2007 by the Genetics Society of America DOI: 10.1534/genetics.107.080689
 

Summary:  -binding cassette (ABC) transporter homologous to mammalian multidrug resistance proteins, functions... , another ABC transporter that acts in parallel to MRP-4 for the formation of birefringent material... in the gut granule. ATP-binding cassette (ABC) transporters ...

  

Source: Hermann, Greg J. - Department of Biology, Lewis and Clark College

 

Collection: Biology and Medicine

 
70 James P. Barnett, Robyn T. Eijlander, Sharon Mendel, Andrew McCarthy, Ren van der Ploeg, Anja Nenninger, Rense Rozeboom, Jan Maarten van Dijl,
 

Summary:  systems of Bacillus subtilis The Tat system transports folded proteins across the bacterial plasma... membrane. In Gram-negative bacteria, membrane-bound TatABC subunits are all essential for activity, whereas... -arginine translocation (Tat) pathway is involved in the transport of proteins across the chloroplast thylakoid ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
71 ANNOUNCEMENT Project Atmospheric Brown Cloud (ABC) 2006 TRAINING SCHOOL
 

Summary:  ANNOUNCEMENT Project Atmospheric Brown Cloud (ABC) 2006 TRAINING SCHOOL Project ABC Science... in a special training school conducted by Project ABC during 4-14 December 2006 in Asia. · Lecturures... Course Director" at: For US students: <ABC_Training-School@fiji.ucsd.edu> For Asian students: ...

  

Source: Goldstein, Allen - Department of Environmental Science Policy and Management, University of California at Berkeley

 

Collection: Environmental Sciences and Ecology

 
72 Plant Cuticular Lipid Export Requires an ABC Transporter
 

Summary:  Plant Cuticular Lipid Export Requires an ABC Transporter Jamie A. Pighin,1 * Huanquan Zheng,1... caused by a defective peroxisomal aden- osine triphosphate binding cassette (ABC) transporter. We found... that the CER5 gene encodes an ABC transporter localized in the ...

  

Source: Kunst, Ljerka - Department of Botany, University of British Columbia; Western, Tamara L. - Department of Biology, McGill University

 

Collection: Biology and Medicine

 
73 nAture methods | VOL.8 NO.2 | FEBRUARY2011 | 159 Phenotypes that might otherwise reveal a gene's function
 

Summary:  with mutations in nine genes, including seven ABC transporter genes5. This strain is hypersensitive to many... cells. Somatic or germline mutations in at least ten human ABC transporter genes affect drug sensitivity... - ceuticals. For example, ATP-binding cassette ...

  

Source: Harvard University, Center for Cancer Systems Biology; Roth, Frederick - Department of Biological Chemistry and Molecular Pharmacology, Harvard University

 

Collection: Biology and Medicine ; Biotechnology

 
74 1. Ajouz, B., C. Berrier, A. Garrigues, M. Besnard, and A. Ghazi. 1998. Release of thioredoxin via the mechanosensitive channel MscL during osmotic downshock of Escherichia coli cells. J.Biol.Chem. 273:26670-
 

Summary:  subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis. EMBO J. 19... . 1998. The ABC maltose transporter. Mol.Microbiol. 29:685-694. 37. Ellis, R. J. 2001. Macromolecular... . and D. C. Wiley. 2001. Structure of the ABC ATPase domain of human TAP1, the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
75 Candida Drug Resistance Protein 1, a Major Multidrug ATP Binding Cassette Transporter of Candida albicans, Translocates Fluorescent Phospholipids in a
 

Summary:  . Overexpression of the multidrug transporter Cdr1p (Can- dida drug resistance protein 1), a member of the ABC1... , thus facilitating cell survival (4-6). Cdr1p, like other ABC transporters, uses ATP hydrolysis to power... the transport of substrates across membranes. Also, like most ...

  

Source: Menon, Anant K. - Menon Lab, Weill Medical College, Cornell University

 

Collection: Biology and Medicine

 
76 On the osmotic signal and osmosensing mechanism of an
 

Summary:  On the osmotic signal and osmosensing mechanism of an ABC transport system #12;2 Voor mijn ouders... Cover: On the osmotic signal and osmosensing mechanism of an ABC transport system Cover design: Tiemen... signal and osmosensing mechanism of an ABC transport system ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
77 Peptide transport in microorganisms Specificity and selectivity determinants of peptide
 

Summary:  (ABC) transporters, the latter utilizing single or multiple peptide-binding proteins with overlapping... of their cognate ABC transporters. Besides reviewing the current data on binding specificity and transport... ATP- binding cassette (ABC) ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
78 A survey of integral a-helical membrane proteins Libusha Kelly Ursula Pieper Narayanan Eswar
 

Summary:  domains of the human ABC transporter superfamily, (2) to identify the multidrug resistance-associated mem... Membrane proteins Á Superfamily analysis Á Multidrug resistance Á ABC transporters Á Target selection... of the clinically important human ABC transporter ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
79 Mol. Biol. Evol. 18(9):17711788. 2001 2001 by the Society for Molecular Biology and Evolution. ISSN: 0737-4038
 

Summary:  relative to Y16 in HisP) is conserved in other ABC transporter NBDs (summarized in Berger and Welsh 2000... a se- quence alignment with other ABC transporter NBDs; for example, HisP ends exactly at residue G646... of the ABC transporter #12;1778 Chen et al. FIG. 2 ...

  

Source: Cutler, Chris - Department of Biology, Georgia Southern University

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
80 The ABC of ABC-transport in the hyperthermophilic
 

Summary:  The ABC of ABC-transport in the hyperthermophilic archaeon Pyrococcus furiosus #12;This work... ;RIJKSUNIVERSITEIT GRONINGEN The ABC of ABC-transport in the hyperthermophilic archaeon Pyrococcus furiosus... by an inducible, high-affinity ABC-transporter 25 Chapter 3 Biochemical evidence ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology


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81 Galapagos whales hold pollutant mystery > News in Science (ABC Science) http://www.abc.net.au/science/articles/2010/12/06/3085949.htm[12/6/2010 3:21:02 PM]
 

Summary:  Galapagos whales hold pollutant mystery > News in Science (ABC Science) http://www.abc... pollutant mystery Katherine Nightingale ABC Whales living near the Galapagos Islands appear to have been... , industry, agricultural practices - all of those contaminants end Browse the archiveSearch ABC Science Share

  

Source: Rock, Chris - Department of Biological Sciences, Texas Tech University

 

Collection: Biology and Medicine

 
82 Multiple Membrane-Cytoplasmic Domain Contacts in the Cystic Fibrosis Transmembrane Conductance Regulator
 

Summary:  -binding cassette (ABC) pro- teins but functions as an ion channel rather than an active transporter. The chloride... , the crystal structures of several bacterial ABC transporter proteins have been recently solved (14... -linking T123C (CL1) with S428C (NBD) of the multidrug ABC ...

  

Source: Dokholyan, Nikolay V. - Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill

 

Collection: Physics ; Biology and Medicine

 
83 Deleterious mutation prediction in the secondary structure of RNAs
 

Summary:  of the natural P5abc subdomain, with the 4 bp included in the P5b stem, as in Cate et al. (22). (D) Mutated... Deleterious mutation prediction in the secondary structure of RNAs Danny Barash* Genome Diversity... predicting deleterious mutations have recently been investigated for proteins, mainly by ...

  

Source: Barash, Danny - Department of Computer Science, Ben Gurion University

 

Collection: Chemistry

 
84 Supplemental Information. Supplemental Text
 

Summary:  acids starting from residue 2158 is highly conserved in ABC transporters and may carry a regulatory... to ABC1 and related ABCA transporters: identification of N-linked glycosylation sites. J. Biol. Chem... transporters (see Methods). Residues with disease-causing missense ...

  

Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University

 

Collection: Biology and Medicine

 
85 The P5abc Peripheral Element Facilitates Preorganization of the Tetrahymena Group I Ribozyme for Catalysis
 

Summary:  , the hinge region (J5/5a) of the ribozyme is highly tolerant to mutation (50). Further, addition of P5abc... of the Ribozyme Are Affected by P5abc? Structural, phylogenetic, and mutational data show that P5abc contacts... The P5abc Peripheral Element Facilitates ...

  

Source: Doudna, Jennifer A. - Department of Molecular and Cell Biology, University of California at Berkeley; Herschlag, Dan - Department of Biochemistry, Stanford University

 

Collection: Biology and Medicine

 
86 List of publications Jacobs, M. H., T. v.d. Heide, A. J. Driessen, and W. N. Konings. 1996. Glutamate transport in
 

Summary:  .Bacteriol. 182:203-206. Heide, T. v. d. and B. Poolman. 2000. Osmoregulated ABC transport system of Lactococcus... of an ABC transport system for glycine betaine. EMBO J. 20:7022-7032. Wood, J. M., E. Bremer, L. N. Csonka... and function of osmoregulated ABC ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
87 TheJournalofGeneralPhysiology 17 J. Gen. Physiol. The Rockefeller University Press 0022-1295/2003/01/17/20 $8.00
 

Summary:  of CFTR's NBDs. key words: ABC transporters · single-channels kinetics · ATP binding and hydrolysis... of ABC transport proteins and, like other members, shows intrinsic ATP binding and hydrolytic activity... or NBD2 hint at this functional asymmetry. In several other ABC pro- teins, ...

  

Source: Gadsby, David - Laboratory of Cardiac/Membrane Physiology, Rockefeller University

 

Collection: Biology and Medicine

 
88 AjMutator: A Tool For The Mutation Analysis Of AspectJ Pointcut Descriptors
 

Summary:  AjMutator: A Tool For The Mutation Analysis Of AspectJ Pointcut Descriptors Romain Delamare, Benoit... of joinpoints where the advices are woven. In this paper we present a tool, AjMutator, for the mutation analysis... of PCDs. AjMu- tator implements several mutation operators that intro- ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
89 ABC transporters: 1, 2 or 4 substrate-binding Tiemen van der Heide and Bert Poolman
 

Summary:  Chapter 6 65 ABC transporters: 1, 2 or 4 substrate-binding domains? Tiemen van der Heide and Bert... Poolman Summary Two families of ATP-binding Cassette (ABC) transporters have been detected, in which one... transporter complex. The translocator of ABC ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
90 What do the proton motive force-driven multidrug resistance transporters have in common?
 

Summary:  genomes it is now clear that also the ABC-type MDR transporters are common in prokaryotes. Examples... expressing an ABC-type MDR transporter LmrA of L. lactis also gained resistance to this class of antibiotics... -glycoprotein [103] delivered data that were consistent with this hypothesis for ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
91 Summary and concluding remarks Summary and concluding remarks
 

Summary:  -binding cassette (ABC) transporters LmrA (3) and LmrCD (2) use the free energy derived from ATP hydrolysis... for the intrinsic multidrug resistance in L. lactis. These are ABC half-transporter that heterodimerize to form... R operator sequences and consequently in a derepression of lmrCD. The newly ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
92 This Provisional PDF corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon.
 

Summary:  for all trees). These 48 proteins are diverse in nature, including several ABC transporters, nucleotide... , trigalactosyldiacylglycerol 1, lipid transporter, 234 aa], At5g64940 [ABC transporter protein, 487 aa]; "Chlamydia-like" ­ At1... , lipid transporter, and (b) ...

  

Source: Bhattacharya, Debashish - Department of Ecology, Evolution, and Natural Resources, Rutgers University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
93 The Entire N-Terminal Half of TatC is Involved in Twin-Arginine Precursor Eva Holzapfel,,,|| Gottfried Eisner,,|, Meriem Alami,,X Claire M. L. Barrett,O Grant Buchanan,#,3 Iris Luke,,[
 

Summary:  deletion strain transformed with derivatives of pQE-TatABC, in which the indicated mutations in tatC had... mutation leads to a disintegration of the TatABC complex (39), and this would explain the complete block... ., and Berks, B. C. (2005) Characterisation of Tat protein transport ...

  

Source: Palmer, Tracy - Division of Molecular Microbiology, University of Dundee

 

Collection: Biology and Medicine

 
94 Macaulay 2 Worksheet Macaulay 2 is a software system devoted to supporting research in algebraic geometry and com-
 

Summary:  geometry and com- mutative algebra, developed by Daniel R. Grayson and Michael E. Stillman with funding... (2, S) Every polynomial ring in Macaulay2 is equipped with a monomial order. S = ZZ/101[a,b,c] (a+b+c... . The next ring uses MonomialOrder to specify graded lexicographic ordering. S = ZZ/101[a,b,c, ...

  

Source: Smith, Gregory G. - Department of Mathematics and Statistics, Queen's University (Kingston)

 

Collection: Mathematics

 
95 AjMutator: A Tool For The Mutation Analysis Of AspectJ Pointcut Descriptors
 

Summary:  the mutants. As a single modification of an aspect can affect var- AjMutator Mutant Compiler abc Compiler... AjMutator: A Tool For The Mutation Analysis Of AspectJ Pointcut Descriptors Romain Delamare, Benoit... of joinpoints where the advices are woven. In this paper we present a tool, ...

  

Source: Jézéquel, Jean-Marc - Triskell Project & IRISA, Université de Rennes

 

Collection: Computer Technologies and Information Sciences

 
96 Heterologously expressed bacterial and human multidrug resistance proteins confer cadmium resistance
 

Summary:  binding cassette (ABC) superfamily of transporters... ,whosefunctionsincludetheATP-dependentextrusionofamphiphilic compounds out of the cell (70). In addition to MDR1, other ABC transporters have been implicated in MDR... metals pose a serious threat to the environment. Several ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
97 JOURNAL OF BACTERIOLOGY, Oct. 1992, p. 6634-6643 0021-9193/92/206634-10$02.00/0
 

Summary:  with a location within the first portion of the operon, upstream of the eutABC genes. The single mutation... , mutation eut-262 increases eutR gene expression but does not provide expression of all of the eutABC genes... somewhere within the eutABC gene cluster (Fig. 1). The effect of ...

  

Source: California at Davis, University of - Center for Genetics and Development, Roth Laboratory

 

Collection: Biology and Medicine ; Biotechnology

 
98 Introduction Transport proteins
 

Summary:  commonly found in two classes, primary transporters more particularly the ATP Binding Cassette (ABC... ) superfamily, and secondary transporters. ABC transporters derive the energy required for transport from... . coli and Bacillus subtilis, secondary ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
99 Psychosis and autism as diametrical disorders of the social brain
 

Summary:  that cause it (paternal UPD15, imprinting center alteration, and UBE3A mutation), as well as in some mouse

  

Source: Haig, David - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology

 
100 PROTEIN INTERACTIONS AND DISEASE MARICEL KANN
 

Summary:  of protein-protein inter- actions. Kelly et al. study ABC transporter proteins which are involved in sub... - strate transport through the membrane. By investigating intra-transporter do- main interfaces... . Disease-related mutations were mapped into these interfaces. Pulim et al. ...

  

Source: Radivojac, Predrag - School of Informatics, Indiana University

 

Collection: Computer Technologies and Information Sciences


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