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Sample search results for: a-type nuclear lamins

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1 The truncated prelamin A in Hutchinson-Gilford progeria syndrome alters segregation of A-type and B-type lamin homopolymers
 

Summary:  proteins at the nuclear periphery (3). B-type lamins are constitutive whereas A- type lamins (lamins... progerin coassembles with lamin B1 and lamin A to form a mixed heteropolymer in which A-type and B... ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
2 Dynamic Properties of Nuclear Lamins: Lamin B Is Associated with Sites of DNA Replication
 

Summary:  there are two major A-type lamins (lamins A and C) produced by alternate splicing of the same gene. These lamins... Dynamic Properties of Nuclear Lamins: Lamin B Is Associated with Sites of DNA Replication Robert D... ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
3 Fate of the Nuclear Lamina during Caenorhabditis elegans Apoptosis Yonatan B. Tzur,* Bradley M. Hersh, H. Robert Horvitz, and Yosef Gruenbaum*,1
 

Summary:  ., Nagashima, K., Stewart, C. L., and Burke, B. (1999) Loss of A-type lamin expression compromises nuclear... . Vertebrates contain A-type lamins encoded by the LMNA gene, in addition to at least one B-type lamin (Stuurman... Ce-lamin is degraded ...

  

Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
4 Nuclear lamins: building blocks of nuclear architecture
 

Summary:  2), encoding seven alternatively spliced iso- forms. The A-type lamins A, A 10, C, and C2 are all... ;isotypes (three A-types and two B-types) and there ap- pears to be variability in the thickness of lamin B... and Hausen 1985). Further- more, the induction of A-type ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
5 The Rockefeller University Press, 0021-9525/2002/2/603/6 $5.00 The Journal of Cell Biology, Volume 156, Number 4, February 18, 2002 603608
 

Summary:  -type lamins. Micro- injection of NLA disrupted the organization of both B- and A-type lamins (C and D... Report Alteration of nuclear lamin organization inhibits RNA polymerase II­dependent transcription... in part by interactions with structural components of the nucleus. The ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
6 The Rockefeller University Press, 0021-9525/2000/12/1155/14 $5.00 The Journal of Cell Biology, Volume 151, Number 6, December 11, 2000 11551168
 

Summary:  of B- and A-type lamins with chromosomes was also compared with other compo- nents of the nuclear... , while A-type lamins are expressed only in differentiated cells (Benavente et al., 1985; Stewart... , the A-type lamins include ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
7 The Rockefeller University Press, 0021-9525/97/03/1201/12 $2.00 The Journal of Cell Biology, Volume 136, Number 6, March 24, 1997 12011212 1201
 

Summary:  are expressed in all cells, while the A-type lamins are expressed in differentiated cells (40). In Xeno- pus... , Volume 136, Number 6, March 24, 1997 1201­1212 1201 Disruption of Nuclear Lamin Organization Alters... comprising the lamina, the nuclear lamins, are ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
8 Viral Mimicry of Cdc2/Cyclin-Dependent Kinase 1 Mediates Disruption of Nuclear Lamina during Human
 

Summary:  -filament proteins known as lamins [3,4]. There are two major classes of lamins in mammalian cells: A-type lamins... not reported. We wished to determine whether UL97 can directly phosphor- ylate the largest of the A-type lamins... . Interestingly, CDK1 mediated ...

  

Source: Knipe, David M. - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
9 Introduction Control of gene expression is a complex process involving
 

Summary:  is developmentally regulated: analogies with vertebrate A-type lamins. J. Cell Sci. 108, 3189-3198. Roberts, D. B... JIL-1 regions as bait. Here we report that the Drosophila nuclear lamin Dm0 directly interacts... of the inner nuclear membrane (Goldman et al., 2002). In Drosophila there ...

  

Source: Johansen, Kristen M - Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University

 

Collection: Biology and Medicine

 
10 This is pre-copy editing, author-produced PDF of an article published in International Review of Cytology 2005 vol 246 , pp 231-279
 

Summary:  recent studies have also shown that cells expressing mutant A-type lamins have abnormalities in nuclear... in A-type nuclear lamins as a cause of an inherited disorder. Subsequently, Fatkin et al. (1999) showed... 3. Emerin C. A-type ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
11 Introduction Cells respond to mechanical cues from their environment in
 

Summary:  ., 1999). At least eight diseases have been linked to mutations in A-type lamins or lamin- binding... -84. Zastrow, M. S., Vlcek, S. and Wilson, K. L. (2004). Proteins that bind A- type lamins: integrating... proteins are anchored to lamins, which ...

  

Source: Discher, Dennis - Department of Bioengineering, University of Pennsylvania

 

Collection: Engineering ; Biology and Medicine

 
12 Granulocytic nuclear differentiation of lamin B receptordeficient mouse EPRO cells
 

Summary:  nuclear membrane proteins on A-type lamins. Biochemistry. 2006;45:1374­1382. 48. Agrelo R, Setien F... Granulocytic nuclear differentiation of lamin B receptor­deficient mouse EPRO cells Monika Zwergera... /ic) granulo- cytic forms of EPRO cells were analyzed for the expression of ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
13 Molecular Biology of the Cell Vol. 13, 892901, March 2002
 

Summary:  ., Nagashima, K., Stewart, C.L., and Burke, B. (1999). Loss of A-type lamin expression compromises nuclear... as monitored by GFP-tagged A-type lamins. J. Cell Sci. 112, 3463­3475. Cohen, M., Lee, K.K., Wilson, K... -84 protein colocalizes with Ce-lamin at the ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
14 Molecular Biology of the Cell Vol. 19, 237247, January 2008
 

Summary:  -type lamin is a splice variant missing the CaaX motif, whereas A-type lamins are farnesylated but the group... ., 2005). These morphological changes are dependent on A- and B-type nuclear lamins, type-V intermediate... (Prunuske and Ullman, 2006). Mutations in lamin A ...

  

Source: Unrau, Peter J.- Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
15 JOURNAL OF VIROLOGY, June 2004, p. 55915600 Vol. 78, No. 11 0022-538X/04/$08.00 0 DOI: 10.1128/JVI.78.11.55915600.2004
 

Summary:  intranuclear A-type lamins. J. Cell Sci. 113:3473­3484. 7. Dechat, T., S. Vlcek, and R. Foisner. 2000. Review... with these changes, the nuclear lamina components lamin A/C and lamin-associated protein 2 appear to be redistributed... nuclear egress by recruiting the ...

  

Source: Knipe, David M. - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
16 Journal of Biomechanics 40 (2007) 20532062 Mechanics and deformation of the nucleus in micropipette aspiration
 

Summary:  (Newport and Forbes, 1987). Mammalian cells produce two lamin protein types, referred to as A-type and B... -type. A-type lamins, which are further categorized as lamin A, AD10 and C are the product of a single gene... in the nuclear lamina, such as mutations in the ...

  

Source: Mofrad, Mohammad R. K. - Department of Bioengineering, University of California at Berkeley; Sniadecki, Nathan J. - Department of Mechanical Engineering, University of Washington at Seattle; Vaziri, Ashkan - Department of Mechanical and Industrial Engineering, Northeastern University

 

Collection: Biology and Medicine ; Engineering

 
17 Mechanical forces influence the growth and shape of virtually every tissue and organ in
 

Summary:  of nuclear organization and gene function53 . These lamins can be divided into two subgroups: A-type lamins... that are deficient for A-type lamins have decreased viability, reduced expression of mechanosensitive genes... simi- lar effects, which suggests that the ...

  

Source: Ingber, Donald E. - Vascular Biology Program, Harvard University; Sniadecki, Nathan J. - Department of Mechanical Engineering, University of Washington at Seattle

 

Collection: Biology and Medicine ; Engineering

 
18 Nuclear Envelope and Chromatin Compositional Differences Comparing Undifferentiated and Retinoic Acid-and
 

Summary:  nuclear envelope deformability due to lamins A/C and B1 deficiency; an increase in nuclear surface area... . Employing antibodies to lamin B2, LBR, and LAP2 , ELCS appeared as brightly stained regions on the nuclear... regions (presumptive ELCS) in the nuclear ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
19 The Rockefeller University Press, 0021-9525/2000/06/1179/13 $5.00 The Journal of Cell Biology, Volume 149, Number 6, June 12, 2000 11791191
 

Summary:  , Volume 149, Number 6, June 12, 2000 1179­1191 http://www.jcb.org 1179 Disruption of Nuclear Lamin... , Germany Abstract. The role of nuclear lamins in DNA replica- tion is unclear.To address this, nuclei were... · lamina · intermediate filaments · nuclear organization · ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
20 The granulocyte nucleus and lamin B receptor: avoiding Katrin Hoffmann & Karl Sperling & Ada L. Olins &
 

Summary:  nuclear membrane proteins on A-type lamins. Biochemistry 45:1374­1382 Park BH, Dolen J, Snyder B (1977... and sequencing studies identified lamin B receptor (LBR), an integral membrane protein of the nuclear envelope... nuclear envelope lamin ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine


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21 Progeroid syndromes are heritable human disorders with featuresthatsuggestprematureageing1
 

Summary:  that leads to aberrant splicing of LMNA, the gene that encodes the A-type nuclear lamins48­50 . In most... and elasticity to the nuclear lamina53 . Although the A-types lamins are highly enriched at the nuclear periphery... that progerin ...

  

Source: Monnat, Ray - Department of Genome Sciences, University of Washington at Seattle

 

Collection: Biology and Medicine

 
22 RESEARCH PAPER Composition of the plant nuclear envelope: theme and
 

Summary:  , Burke B. 1999. Loss of A-type lamin expression compromises nuclear envelope integrity leading... ] Zastrow MS, Vlcek S, Wilson KL. 2004. Proteins that bind A-type lamins: integrating isolated clues... , and the role and fate of the nuclear envelope during mitosis. Key ...

  

Source: Meier, Iris - Department of Plant Cellular and Molecular Biology, Ohio State University; Sayre, Richard - Department of Plant Cellular and Molecular Biology, Ohio State University

 

Collection: Biology and Medicine ; Renewable Energy

 
23 Author's personal copy Structure and stability of the lamin A tail domain and HGPS mutant
 

Summary:  mechanical interest since the loss of lamin A appears to influence nuclear mechanics more than other A-type... in mice aside from some nuclear weakening as long as other A-type lamins are present (such as lamin C... of intermediate fila- ments ...

  

Source: Buehler, Markus J. - Department of Civil and Environmental Engineering, Massachusetts Institute of Technology (MIT)

 

Collection: Engineering ; Materials Science

 
24 Construction and Building Materials 17 (2003) 405437 0950-0618/03/$ -see front matter 2003 Elsevier Ltd. All rights reserved.
 

Summary:  are made of one or more `qualified' laminates. The quali- fying procedure includes a number of mechanical... a set of tests that are completed on trial laminates or on lami- nates cut from production parts... are essentially equiv- alent to those of the qualified laminates. The testing regime for part acceptance

  

Source: Bank, Lawrence C. - Department of Civil Engineering, City College, City University of New York

 

Collection: Engineering

 
25 structural communications Acta Cryst. (2009). F65, 665670 doi:10.1107/S1744309109020302 665
 

Summary:  filamentous meshwork, the lamina, that underlies the inner nuclear membrane. A-type lamins have recently... 2009 PDB Reference: R482W mutant of lamin A/C, 3gef, r3gefsf. Proteins of the A-type lamin family... in the lamin A/C gene (LMNA), which ...

  

Source: Wlodawer, Alexander - Macromolecular Crystallography Laboratory, National Cancer Institute

 

Collection: Chemistry ; Biology and Medicine

 
26 doi:10.1093/brain/awl023 Brain (2006), 129, 9961013 Nuclear envelope dystrophies show a
 

Summary:  are classified into A and B types; B types (B1 and/or B2 genes) are ubiquitously expressed. The A-type lamins... of the lamina are the nuclear lamins. Nuclear lamins are type V intermediate fila- ments and have globular amino... and carboxyl termini, with four ...

  

Source: Virginia Tech - Department of Electrical and Computer Engineering, Computational Bioinformatics and Bioimaging Laboratory

 

Collection: Engineering

 
27 Pathway of Incorporation of Microinjected Lamin A into the Nuclear Envelope
 

Summary:  Pathway of Incorporation of Microinjected Lamin A into the Nuclear Envelope Anne E. Goldman, Robert... and number as the biotinylated lamin A becomes associated with the en- dogenous nuclear lamina. Eventually... , the typical nu- clear rim staining pattern normally revealed by immu- nofluorescence with ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
28 Cell, Vol. 62, 69-106, July 13, 1990, Copyright 0 1990 by Cell Press Interphase Nuclear Envelope Lamins Form a
 

Summary:  Lamins Form a Discontinuous Network That Interacts with Only a Fraction of the Chromatin in the Nuclear... against nuclear envelope lamin proteins have been used in conjunction with three- dimensional light... large voids in the nuclear periphery containing little or no ...

  

Source: Agard, David - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biotechnology ; Biology and Medicine

 
29 Available online at www.sciencedirect.com Gene positioning and expression
 

Summary:  2008, 180:51-65. 25. Lee DC, Welton KL, Smith ED, Kennedy BK: A-type nuclear lamins act... . Metazoan cells possess a lamina structure at the nuclear periphery, a fibrous mesh made up of lamins... with the nuclear laminamay represent a default state for silenced loci. ...

  

Source: Brickner, Jason - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
30 Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for
 

Summary:  aging disease resulting from a mutation in the LMNA gene, which encodes nuclear lamins A and C. Lamin... transfection of GFP­lamin A-WT had no effect on nuclear morphology, given that the nuclei maintained... of abnormal nuclear morphology, the localization of ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
31 The Rockefeller University Press, 0021-9525/2001/07/61/10 $5.00 The Journal of Cell Biology, Volume 154, Number 1, July 9, 2001 6170
 

Summary:  A role for nuclear lamins in nuclear envelope assembly Reynold I. Lopez-Soler,1 Robert D. Moir,1 Timothy... -terminal domain of Xenopus lamin B3 (LB3T) prevents nuclear envelope assembly in Xe- nopus interphase extracts... reassembly in daughter cells. In particular, the role of ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
32 Vol. 265. No. 21, Issue of July 25, pp. X2636-12641,lSSO Printed in U.S.A.
 

Summary:  is unfolded in urea. During nuclear envelope breakdown the lamin is released as a mixture of oligomers... of Lamin Dimers in the Nuclear Envelope of Surf Clam Oocytes-Whole unactivated surf clam oocytes were lysed... CHEMKWRY 0 1990 by The American Society for Biochemistry and Molecular Biology, Inc. ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
33 INTRODUCTION Despite the enormous current interest in gene expression and
 

Summary:  , designated nuclear lamins (Gerace and Blobel, 1980), have undergone extensive molecular characterization... to and assembly into the nuclear lamina is now understood, as well as the mechanism by which lamins depolymerize... and biochemical evidence have long suggested that lamins ...

  

Source: Agard, David - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biotechnology ; Biology and Medicine

 
34 THEJOURNALOFCELLBIOLOGY JCB: ARTICLE
 

Summary:  and Physiology, Washington University School of Medicine, St. Louis, MO 63110 S un1 and 2 are A-type lamin... stress. Cells depleted of either A-type lamins or emerin, an INM protein, exhibit reduced cytoplasmic... , 2005, 2006). In humans, the loss or mutation of either A-type ...

  

Source: Panté, Nelly - Department of Zoology, University of British Columbia

 

Collection: Biology and Medicine

 
35 Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans
 

Summary:  ). Lamin A is a key protein within the nuclear lamina, an inter- mediate filament meshwork lining the inner... , the structural abnormality in lamin A is apparently sufficient to impair nuclear envelope integrity and cause... to be important for the targeting of prelamin A to the nuclear ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
36 Granzymes A and B Directly Cleave Lamins and Disrupt the Nuclear Lamina during Granule-Mediated Cytolysis
 

Summary:  Granzymes A and B Directly Cleave Lamins and Disrupt the Nuclear Lamina during Granule- Mediated... )proteases and perforin. The lamins, which maintain qu the structuralintegrity of the nuclear envelope, are cleaved by (2... the inner nuclear ca membrane (20). Lamins ...

  

Source: Lieberman, Judy - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
37 Abstract The association of lamin and lamin binding proteins with peripheral heterochromatin suggests the
 

Summary:  lamin to the inner nuclear membrane. We show that the LamAri3 allele strongly increased silencing of wm4... of these func- tions of the nuclear lamins is to serve as scaffold pro- teins that provide attachment sites... X box which localizes lamin to the inner nuclear ...

  

Source: Johansen, Kristen M - Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University

 

Collection: Biology and Medicine

 
38 Power-Law Rheology of Isolated Nuclei with Deformation Mapping of Nuclear Substructures
 

Summary:  ., S. Vlcek, and K. L. Wilson. 2004. Proteins that bind A-type lamins: integrating isolated clues. J... motivate a deeper understanding of nuclear mechanics. Chromatin and green fluorescent protein-lamin B... expression (9­11). Separating the roles of lamins and chromatin is vital to ...

  

Source: Discher, Dennis - Department of Bioengineering, University of Pennsylvania

 

Collection: Engineering ; Biology and Medicine

 
39 BioMed Central Page 1 of 7
 

Summary:  laminopathies which affect nuclear lamins. Mutations in two genes, LMNA and ZMPSTE24, have been found... - thies which affect nuclear lamins and include several phe- notypes (figure 1). Mutations in the gene... LMNA have been identified in the majority of cases of HGPS. The gene LMNA encodes ...

  

Source: Lycan, Deborah E. - Department of Biology, Lewis and Clark College

 

Collection: Biology and Medicine

 
40 CB26CH09-Starr ARI 19 May 2010 21:40 Interactions between Nuclei
 

Summary:  al. 2004). Klarsicht localization to the nuclear en- velope requires lamin and the SUN protein... by mutations in the nuclear envelope proteins emerin or lamin (Bione et al. 1994, Bonne et al. 1999). EDMD... and the Cytoskeleton are Mediated by SUN-KASH Nuclear-Envelope Bridges Daniel A. ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine


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41 Structure, Subnuclear Distribution, and Nuclear Matrix Association of the Mammalian Telomeric Complex
 

Summary:  and transferred to nitrocellulose. A-type lamins were detected by monoclonal antibody (mAb) 41CC4 (Burke et al... a peripheral substruc- ture of the nuclear matrix that is highly enriched for lamins proteins (Izaurralde et al... in preparations enriched for nuclear envelope ...

  

Source: de Lange, Titia - Laboratory for Cell Biology and Genetics, Rockefeller University

 

Collection: Biology and Medicine

 
42 Proc. Natl. Acad. Sci. USA Vol. 93, pp. 83958400, August 1996
 

Summary:  efficiencies. Mch2 also cleaved recombinant and nuclear lamin A at a conserved VEIDsNG sequence located... , cleavage of the nuclear lamins is a proteolytic event that appears to be required for completion of nuclear... . Zn2 also blocks the cleavage of endogenous ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
43 Biomechanics of single cells under compression
 

Summary:  to maintain nuclear integrity: A-type lamins. The load- bearing properties of the two cell types... hypotheses are currently exploited. The first hypothesis states that mutations in A-type lamins cause a loss... this assumption. The present studies revealed a direct correlation between ...

  

Source: Technische Universiteit Eindhoven, Materials Technology Institute

 

Collection: Biology and Medicine ; Materials Science

 
44 brief communications NATURE CELL BIOLOGY VOL 3 SEPTEMBER 2001 http://cellbio.nature.com848
 

Summary:  A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila Karen Guillemin... .W.) e-mail: krasnow@cmgm.stanford.edu Nuclear lamins are intermediate filaments that compose the nuclear... for nuclear assembly, organization and maintenance. ...

  

Source: Krasnow, Mark A. - Department of Biochemistry, Stanford University

 

Collection: Biology and Medicine

 
45 mTOR Complex 1 Regulates Lipin 1 Localization to Control
 

Summary:  of work suggests that A-type lamins colocal- ize with transcriptional regulators (Johnson et al., 2004... for nuclear eccentricity based on lamin A immunofluorescence by image analysis software (Carpenter et al... the structure of the lamin A-containing nuclear ...

  

Source: Sabatini, David M. - Whitehead Institute for Biomedical Research & Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
46 Topology of Yeast Ndc1p: Predictions for the Human NDC1/NET3
 

Summary:  BK. 2005. A-type nuclear lamins, progerias and other degenerative disorders. Mech Ageing Dev 126... of a nuclear lamina, a protein- aceous structure composed of intermediate filament-like proteins termed lamins... - lope, lamins and nuclear ...

  

Source: Forbes, Douglass - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
47 Proc. Nat!. Acad. Sci. USA Vol. 85, pp. 2994-2998, May 1988
 

Summary:  activity, which phosphorylates in vitro the nuclear lamins, a 52-kilodalton protein, and several unknown... that the lamins are members of the intermediate filament protein family (7-11). The nuclear lamins... AMP-independent protein kinase activity, which is capable of phosphorylating ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
48 2006 Nature Publishing Group Karyopherin-mediated import of integral
 

Summary:  inner nuclear membrane proteins on A-type lamins. Biochemistry 45, 1374­-1382 (2006). 24. Horton, P... of the INM contribute to the organiz- ation of lamins and chromatin at the nuclear envelope1 ; mutations... . Vaughan, A. et al. Both emerin and lamin C depend on ...

  

Source: King, Megan - Department of Cell Biology, Yale University

 

Collection: Biology and Medicine

 
49 Biochem. J. (2005) 387, 129138 (Printed in Great Britain) 129 Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24
 

Summary:  [9]. Indeed, this sequence is recognized to be unique among mammalian proteins to A-type lamins... School of Medicine, 725 N Wolfe St., Baltimore, MD 21205, U.S.A. The nuclear lamins form a karyoskeleton... or by a geranylgeranyl group when the amino acid X is a leucine. The farnesylated ...

  

Source: Hrycyna, Christine A. - Department of Chemistry, Purdue University

 

Collection: Biology and Medicine ; Chemistry

 
50 Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted
 

Summary:  to generate mature lamin A, which is a structural protein of the nuclear lamina. The mutant prelamin A in HGPS... with the inner nuclear membrane, where the protein is cleaved, releasing mature lamin A (9, 11). In the absence... - deficient fibroblasts, which accumulate wild-type farnesyl pre- ...

  

Source: Gelb, Michael - Departments of Chemistry & Biochemistry, University of Washington at Seattle

 

Collection: Chemistry ; Biology and Medicine

 
51 Dynamics of Chromatin Decondensation Reveals the Structural Integrity of a Mechanically Prestressed Nucleus
 

Summary:  rupture of the nuclear membrane and lamin network due to this entropic pressure were observed... cells is maintained by the nuclear membrane, lamin scaffold, and chromatin orga- nization (1... the nuclear periphery and are known to be anchored to the lamin network at ...

  

Source: Mahadevan, L. - School of Engineering and Applied Sciences, Harvard University

 

Collection: Engineering ; Materials Science

 
52 Progeria, a rare disorder in children that causes extremely rap-id aging and usually ends in death from cardiovascular disease
 

Summary:  principles of building materials at the macroscale. The brittle nuclear skeleton in the mutated lamin... the end of the lamin A protein. The lamin A protein tail helps provide structural support for the cell... 's nuclear membrane. Studies have shown that in these mutated proteins, the ...

  

Source: Entekhabi, Dara - Kavli Institute for Astrophysics and Space Research & Department of Civil and Environmental Engineering, Massachusetts Institute of Technology (MIT)

 

Collection: Engineering ; Geosciences

 
53 410 nature genetics volume 31 august 2002 Mutations in the gene encoding the lamin B receptor
 

Summary:  to the inner nuclear membrane; it targets hete- rochromatin and lamins to the nuclear membrane7,8. Lym... that expression of the lamin B receptor affects neutrophil nuclear shape and chromatin distribution in a dose... nuclear morphology in mammalian cells ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
54 Volume 22 May 15, 2011 1739 Multiple mechanisms actively target the SUN
 

Summary:  nuclear membrane Erin C. Tapley, Nina Ly, and Daniel A. Starr Department of Molecular and Cellular Biology... correspondence to: Daniel Starr (dastarr@ucdavis.edu). Abbreviations used: cNLS, classical nuclear localization... re- ticulum; GTP, guanosine 5'-triphosphate; INM, inner nuclear membrane; IMN-SM, inner ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
55 Current Biology 16, 801807, April 18, 2006 2006 Elsevier Ltd All rights reserved DOI 10.1016/j.cub.2006.03.066 The Origin of Centrosomes
 

Summary:  of Drosophila lamin C is devel- opmentally regulated: Analogies with vertebrate A-type lamins. J. Cell Sci. 108... ;(n = 75), anti-lamin highlighted the nuclear envelope of the single maternal pronucleus... from accessory nuclei (AN), organelles derived from the oocyte ...

  

Source: Sullivan, William T. - Department of Molecular, Cell, and Developmental Biology, University of California at Santa Cruz

 

Collection: Biology and Medicine

 
56 Physical plasticity of the nucleus in stem cell differentiation
 

Summary:  such as lamins in ESCs (7, 17). The limiting ratio for Lnuc/Lcell (i.e., nuclear:cytoplasmic stiffness) of 0... after treatment with a histone deacetylase inhibitor (26). P = const Nucleolus (B23) Nuclear Lamins A... ). Network of Lamin A/C Modulates Nuclear ...

  

Source: Discher, Dennis - Department of Bioengineering, University of Pennsylvania; Sniadecki, Nathan J. - Department of Mechanical Engineering, University of Washington at Seattle

 

Collection: Biology and Medicine ; Engineering

 
57 Cell Stem Cell Wnts as Self-Renewal Factors
 

Summary:  , A-type lamins are absent from the inner- cell mass (ICM) of the early mouse embryo... ., 2009). The nuclear lamina of essentially all mammalian cell types contains B-type lamins. In contrast... -Hupkes et al. (2010) use DamID to map the interactions between chromatin and the nuclear ...

  

Source: Verheyen, Esther M. - Department of Molecular Biology and Biochemistry, Simon Fraser University

 

Collection: Biology and Medicine

 
58 mTOR complex 1 regulates lipin 1 localization to control the SREBP Timothy R. Peterson 1
 

Summary:  inhibition on the expression of nuclear SREBP proteins. A growing body of work suggests that A-type lamins... the nuclear matrix component, lamin A (Heessen and Fornerod, 2007), as well as DNA, dramatically changed... in lipin 1 localization strongly altered the structure of the ...

  

Source: Carpenter, Anne E. - Broad Institute Imaging Platform, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
59 BioMed Central Page 1 of 18
 

Summary:  that increase the flexibility of the nuclear envelope (reduced lamin content), augment connections... implicated two major factors in the nuclear lobulation process: 1) very low cellular levels of lamins A... to lamin B, chromatin and HP1 [10]. The mechanistic rela- tionships between ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
60 Retinoic Acid Induction of Nuclear Envelope-Limited Chromatin Sheets in HL-60
 

Summary:  revealed that both the DNA and the lamin B were in sheet-like structures (data not shown). Nuclear Envelope... , lamin, and nuclear envelope integrity [45­47]. Thus, we reasoned that the formation of ELCS in HL- 60/S4... were also not observed. In contrast, anti-lamin A/C antibodies ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine


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61 JOURNAL OF VIROLOGY, Oct. 2005, p. 1284012851 Vol. 79, No. 20 0022-538X/05/$08.00 0 doi:10.1128/JVI.79.20.1284012851.2005
 

Summary:  . Using a lamin A-green fluorescent protein fusion, we provide direct evidence that the nuclear lamina... have been shown to interact and colocalize at the nuclear mem- brane, and BFRF1 binds to lamin B... the redistribution of a GFP-lamin A fusion protein. Previous studies have shown ...

  

Source: Knipe, David M. - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
62 Characterization of a novel Dp71 dystrophin-associated protein complex (DAPC) present in the nucleus of HeLa cells: Members of the nuclear
 

Summary:  -immunoprecipitated with the nuclear matrix proteins lamin B1 and actin. The association of members of the nuclear DAPC... with the nuclear matrix proteins lamin B1 and actin. Our findings suggest the presence of a DAPC in the nuclei... vinculin and calnexin antibodies as cytoplasmic ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
63 HIV protease inhibitors and nuclear lamin processing: Getting the right bells and whistles
 

Summary:  HIV protease inhibitors and nuclear lamin processing: Getting the right bells and whistles Steven... A to lamin A, a key structural com- ponent of the nuclear lamina (Fig. 1). In recent years, genetic defects... targeting of lamin A to the nuclear lamina or func- ...

  

Source: Clarke, Steven - Department of Chemistry and Biochemistry, University of California at Los Angeles

 

Collection: Biology and Medicine

 
64 Clinical Features, Molecular Genetics, and Inheritance: Dilated cardiomyopathy (DCM) is a severe disease of heart muscle characterized by progressive
 

Summary:  in LMNA, encoding Lamin A/C Nuclear-Envelope Proteins, Cause Autosomal Recessive Axonal Neuropathy... . Boguslavsky, RL et al. "Nuclear lamin A inhibits adipocyte differentiation: implications for Dunnigan... and are a genetically heterogeneous group. Mutations of the Lamin A/C gene ...

  

Source: Das, Soma - Department of Human Genetics, University of Chicago

 

Collection: Biology and Medicine

 
65 Clinical Features, Molecular Genetics, and Inheritance: Dilated cardiomyopathy (DCM) is a severe disease of heart muscle characterized by progressive
 

Summary:  in LMNA, encoding Lamin A/C Nuclear-Envelope Proteins, Cause Autosomal Recessive Axonal Neuropathy... . Boguslavsky, RL et al. "Nuclear lamin A inhibits adipocyte differentiation: implications for Dunnigan... and are a genetically heterogeneous group. Mutations of the Lamin A/C gene ...

  

Source: Gilad, Yoav - Department of Human Genetics, University of Chicago

 

Collection: Biology and Medicine

 
66 RESEARCH ARTICLE Open Access Identification of new autoantibody specificities
 

Summary:  total and enriched nuclear protein extracts, IgG reactivity for lamin A/C was high in several sera pools... lamin A/C in enriched nuclear protein extract in the sera pool from patients with lcSSc, DU... /7 134 72 54 lcSSc/DU 2317 Histone H2A type 1-J (T) [SwissProt: ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
67 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  envelope; Lamin B receptor; Lamins; Nuclear shape; Heterochromatin Introduction The major human blood... -induced granulocytic differentiation of HL- 60 cells, the integral nuclear envelope protein lamin B receptor (LBR... ), we have employed goat anti-lamin B (C-20, ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
68 Nuclear envelope-limited chromatin sheets (ELCS) and heterochromatin higher order structure
 

Summary:  by a paucity of lamins A/C, a common feature of white blood cells. (5) The expanding nuclear membranes can fuse... , Sodmergen ZZ, Zhang C (2007) Lamin B receptor plays a role in stimulating nuclear envelope production... REVIEW Nuclear envelope-limited chromatin sheets (ELCS) and ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
69 Introduction When envisioning a typical eukaryotic cell, one usually
 

Summary:  retain other proteins at the outer nuclear envelope. This mechanism could be similar to the way lamin... as an inner nuclear membrane component. Syne-1 interacts directly with lamin A and nesprin, both components... of such a bridge hypothesis, Syne- 1 co-immunoprecipitates with the major ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
70 Communication Parvoviral nuclear import: bypassing the host
 

Summary:  shape and morphology, alterations of nuclear lamin immunostaining and breaks in the NE of infected cells... ). In addition, we also observed alterations in the nuclear lamin-A/C immunostaining. These included... of infected cells, mock-infected cells displayed normal continuous ...

  

Source: Panté, Nelly - Department of Zoology, University of British Columbia

 

Collection: Biology and Medicine

 
71 Topology of the Lyubich-Minsky Laminations
 

Summary:  Topology of the Lyubich-Minsky Laminations for Quadratic Maps: Deformation and Rigidity (1st... Laminations? 1 Dynamical Systems Geometric Objects Deformation of Dyn. Deformation of Obj. interpretation - 1... - Orbifolds - Laminations Cf. Fractal sets, like Julia sets, Limit sets Some dynamical systems have geometric

  

Source: Favre, Charles - Institut de Mathématiques de Jussieu, Université Paris 7 - Denis Diderot

 

Collection: Mathematics

 
72 Molecular Biology of the Cell Vol. 12, 503510, February 2001
 

Summary:  filament protein lamin, underlies the nu- clear envelope. The nuclear envelope is disassembled during... , the lamins and peripheral proteins of the nuclear envelope are soluble in the cytoplasm (Gerace and Blobel... ; Terasaki, 2000) and that the integral membrane proteins of the nuclear ...

  

Source: Terasaki, Mark - Department of Cell Biology, University of Connecticut Health Center

 

Collection: Biology and Medicine

 
73 A genetic approach to study the role of nuclear envelope components in
 

Summary:  transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C. J Cell Sci115... 2004 The functions of Klarsicht and nuclear lamin in developmentally regulated nuclear migrations... is on the inner nuclear membrane as opposed to the outer. NE ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
74 Molecular Cell, Vol. 20, 105116, October 7, 2005, Copyright 2005 by Elsevier Inc. DOI 10.1016/j.molcel.2005.08.031 The Ubiquitin Ligase dTopors Directs the Nuclear
 

Summary:  , and mutations in lamin disrupt dTopors localization as well as nuclear organization and activity of the gypsy... . Therefore, we compared the nuclear localization of dTopors and lamin and found that dTopors colocalizes... of partially intact polytenized nuclei (Figure 3E). The anti-lamin ...

  

Source: Corces, Victor G. - Department of Biology, Emory University

 

Collection: Biology and Medicine

 
75 Materials Research, Vol. 9, No. 1, 83-89, 2006 2006 *e-mail: janepaiva@uol.com.br, mirabel@iae.cta.br
 

Summary:  ) arrangement types. The F155TM is an epoxy resin DGEBA (diglycidil-ether of bisphenol-A) type and F584TM... . For this work, it was manufactured four different laminate families (F155/PW, F155/HS, F584/PW and F584/HS... code is a modified epoxy resin type. The laminates were obtained by handing lay-up process ...

  

Source: Laughlin, Robert B. - Department of Physics, Stanford University

 

Collection: Physics

 
76 Current Biology Vol 21 No 11 at-bat, including which fielders were
 

Summary:  of lamins, inner nuclear membrane proteins, and chromosomes. It is separated from the cytoskeleton... with lamins. The presence of multiple SUN proteins in a single organism (at least five in humans... are KASH proteins targeted to the outer nuclear membrane? The nuclear envelope is a ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
77 Centrosome attachment to the C. elegans male pronucleus is dependent on the surface area of the nuclear envelope
 

Summary:  : Nuclear envelope Centrosome Male pronucleus Pronuclear migration Lamin LEM BAF Microtubule aster Outer... manner to build the nuclear lamina (Gruenbaum et al., 2005). In humans, B-type lamins are ubiquitously... of the nuclear envelope Marina Meyerzon a , Zhizhen Gao b , Jin Liu a , ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
78 Eucaryotic cells have a nucleus, which is the epicenter for gene expression. Prokaryotic cells like bacteria do not have a nucleuscells like bacteria do not have a nucleus
 

Summary:  is that the lamins connect to chromatin structure. It has been suggest that mechanical distortion of the nuclear... will be cut out by the aptly named splicosome and reformed into a single strand that exits out of the nuclear... membrane through nuclear pores. In the cytoplasm, it will be transported to ...

  

Source: Sniadecki, Nathan J. - Department of Mechanical Engineering, University of Washington at Seattle

 

Collection: Biology and Medicine ; Engineering

 
79 Deformation of the cell nucleus under indentation: Mechanics and mechanisms
 

Summary:  : the double lipid bilayer, the corti- cal layer composed largely of lamin (nuclear lamina... - van, R.D. Kamm, C.L. Stewart, and R.T. Lee: Lamin A/C defi- ciency causes defective nuclear mechanics... of the nuclear lamina in mouse anterior pituitary cells and immuno- cytochemical ...

  

Source: Mofrad, Mohammad R. K. - Department of Bioengineering, University of California at Berkeley; Vaziri, Ashkan - Department of Mechanical and Industrial Engineering, Northeastern University

 

Collection: Biology and Medicine ; Engineering

 
80 QIN AND BUEHLER VOL. 5 ' NO. 4 ' 30343042 ' 2011 www.acsnano.org
 

Summary:  of imper- fections is generated by the clustering of lamin-associated nuclear pore complexes... of nuclear laminas, including hydrogen bonds, coiled-coil composed of alpha-helices, a lamin A dimer composed... American Chemical Society Flaw Tolerance of Nuclear Intermediate Filament ...

  

Source: Buehler, Markus J. - Department of Civil and Environmental Engineering, Massachusetts Institute of Technology (MIT)

 

Collection: Engineering ; Materials Science


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81 Annual Logging Symposium, June 3-6, 2007 QUANTITATIVE STUDIES OF RELATIVE DIP ANGLE AND BED -
 

Summary:  to the commercial adnVISION675® LWD nuclear tool designed to operate with an 8.25-in stabilizer in an 8... properties on nuclear measurements. Passey et al. (2005) summarized the technical challenges associated... , and relative dip on nuclear measurements acquired in HA/HZ wells. They found that the response of short

  

Source: Torres-Verdín, Carlos - Department of Petroleum and Geosystems Engineering, University of Texas at Austin

 

Collection: Fossil Fuels ; Geosciences

 
82 Inverse first-order reliability method for probabilistic fatigue life prediction of composite laminates under multiaxial loading
 

Summary:  laminates under multiaxial loading Yibing Xiang and Yongming Liu* Department of Civil and Environmental... , such as composite laminates, are under general multiaxial stress state even if the applied loading is uniaxial... . A general methodology for multiaxial fatigue reliability analysis of composite laminates is proposed

  

Source: Liu, Yongming - Department of Civil & Environmental Engineering, Clarkson University

 

Collection: Engineering

 
83 Clinical Features, Molecular Genetics, and Inheritance: Dilated cardiomyopathy (DCM) is a severe disease of heart muscle characterized by progressive
 

Summary:  Lamin A/C Nuclear-Envelope Proteins, Cause Autosomal Recessive Axonal Neuropathy in Human (Charcot... -Marie-Tooth Disorder Type 2) and Mouse". (2002) Am. J. Hum. Genet. 70:726-736. 8. Boguslavsky, RL et al. "Nuclear lamin... and are a genetically heterogeneous group. Mutations of the ...

  

Source: Ober, Carole - Committee on Genetics & Department of Human Genetics, University of Chicago

 

Collection: Biology and Medicine

 
84 JOURNAL OF VIROLOGY, June 1994, p. 3512-3526 Vol. 68, No. 6 0022-538X/94/$04.00+0
 

Summary:  series comparing the distributions of nuclear lamin and ICP8 in the nuclei of cells infected... , and a cellular nuclear lamin protein. ICP8 has previously been shown to localize to large replication compart... a nuclear lamin protein. Data sets consisting of serial ...

  

Source: Knipe, David M. - Department of Microbiology and Molecular Genetics, Harvard University

 

Collection: Biology and Medicine

 
85 European Journal of Cell Biology 84 (2005) 181188 The mechanism of granulocyte nuclear shape determination
 

Summary:  : Neutrophil; Nuclear envelope; Lamins; Lamin B receptor; Heterochromatin; Centrosome; Microtubules... -limited chromatin sheets; LBR, lamin B receptor; MT, microtubules; NE, nuclear envelope; RA, retinoic acid... , due to a paucity of lamins A/C and B1; (2) the ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
86 Deformation-Based Nuclear Morphometry: Capturing Nuclear Shape Variation in HeLa Cells
 

Summary:  . In addition to identi- fying the modes of variation in normal HeLa nuclei, the effects of lamin A/C on nuclear... between cell populations. Here, we use this concept to examine the effects of lamin knockdown on nuclear... information about the interdependency of nuclear morphology and ...

  

Source: Murphy, Robert F. - Department of Biological Sciences & School of Computer Science, Carnegie Mellon University

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
87 Analysis of out-of-plane displacement and stress eld in a piezocomposite plate with functionally graded microstructure
 

Summary:  FGM, Fig. 4(a) type A Electric ®eld (V/mm) 1000 1000 Applied voltage (V) 208 208 Laminate thickness... ) Bimorph FGM, Fig. 4(a) type A Bimorph FGM, Fig. 4(b) type B Electric ®eld (V/mm) 1000 1000 1000 1000... , USA Received 4 October 1999; in revised form 24 March 2000 Abstract A ...

  

Source: Taya, Minoru - Department of Mechanical Engineering, University of Washington at Seattle

 

Collection: Materials Science ; Engineering

 
88 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  is lobulated and exhibits a paucity of nuclear lamins, increasing its capability for deformation. The present... with anti-lamin B2, -LBR, -LAP2b and -SUN2 (see, Figs. 1 and 3) suggested the presence of nuclear lobulation... . Its absence in lamin A/C mutant fibroblasts affects ...

  

Source: Olins, Ada L. - Biology Department, Bowdoin College

 

Collection: Biology and Medicine

 
89 http://cronos.rutgers.edu/~pelegri DEFLECTION MEASUREMENTS OF LAMINATED THIN PLATES USING
 

Summary:  http://cronos.rutgers.edu/~pelegri DEFLECTION MEASUREMENTS OF LAMINATED THIN PLATES USING... Interferometry (ESPI) system has been developed to measure out-of-plane deformations of laminates subjected... fringe for the Al surface, and 11 mm per fringe for the composite laminate. From the results, it can

  

Source: Pelegri, Assimina - Department of Mechanical and Aerospace Engineering, Rutgers University

 

Collection: Materials Science ; Engineering

 
90 Cell, Vol. 108, 301304, February 8, 2002, Copyright 2002 by Cell Press MinireviewA Tense Time
 

Summary:  monitoring lamin-GFP labeled nuclear envelopes in live cells undergoing NEBD (Beaudouin et al., 2002). A grid... . On the other hand, markercence imaging showed that these invaginations contain lamins, inner nuclear membrane... for the Nuclear Envelope somes during metaphase, and ...

  

Source: Rout, Michael P. - Laboratory of Cellular and Structural Biology, Rockefeller University

 

Collection: Biology and Medicine

 
91 10.1101/gad.2021411Access the most recent version at doi: 2011 25: 569-580 originally published online February 28, 2011Genes Dev.
 

Summary:  periphery by an antibody against nuclear Lamin B shows that the MyoD gene is preferentially localized... . (A,B) DNA FISH of MyoD gene (red) in myoblasts. (A) The nuclear periphery is highlighted by anti-Lamin... contour of nuclear lamin from representative images (n ...

  

Source: Eddy, Sean - Janelia Farm Research Campus, Howard Hughes Medical Institute

 

Collection: Biology and Medicine

 
92 Topology of the Lyubich-Minsky Laminations
 

Summary:  Topology of the Lyubich-Minsky Laminations for Quadratic Maps: Deformation and Rigidity (3rd... gr. action Poincare Extension Quotient by the Action hyp. 3-orbifold lamination Extension... cyclic group action -Lamination -Lamination Quotient Lamination Kleinian Group 1 #12;Abstruct of ...

  

Source: Favre, Charles - Institut de Mathématiques de Jussieu, Université Paris 7 - Denis Diderot

 

Collection: Mathematics

 
93 Communication between the cytoskeleton and the nuclear envelope to position the
 

Summary:  nuclear membrane with actin filaments.58 Lamin, a type V intermediate filament, is the major structural... proteins require lamins to localize to the inner nuclear membrane.22,61 Since SUN proteins recruit KASH... proteins to the outer nuclear membrane, lamins ...

  

Source: Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
94 Special Issue 3-D Cell Biology Compartmentalization of the nucleus
 

Summary:  ,36]. Lamin mutants or depletion of lamins reveal that the lamina is not only important for nuclear structure... to precipitate and is therefore hard to interpret [46]. Lamin and matrix proteins are stable nuclear proteins... of chromosomes. The positioning of chromosomes with respect to ...

  

Source: Brickner, Jason - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University

 

Collection: Biology and Medicine

 
95 The life cycle of the metazoan nuclear envelope Daniel J Anderson and Martin W Hetzer
 

Summary:  four classes: components of the nuclear pore, INM- and ONM-proteins and lamins. The first group... . Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science 2006;312:1059­ 1063. [Pub... , Georgatos SD. The lamin B receptor (LBR) provides essential chromatin ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
96 Annu.Rev. Genet. 1992.30:209-37 CopyrightI~ AnnualReviewsInc. All rights reserved
 

Summary:  membraneand mediate nuclear breakdown and reformationduring mitosis. Laminproteins fall into three types, A-type... ...................................... 210 Lipopeptide Pheromones .................................... 213 Nuclear Lamins... -bindingproteins, lipopeptide pheromones, ...

  

Source: Schafer, William R. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
97 A Complex Containing p34 and Cyclin B Phosphorylates the Nuclear Lamin and Disassembles Nuclei of Clam Oocytes in Vitro
 

Summary:  A Complex Containing p34 and Cyclin B Phosphorylates the Nuclear Lamin and Disassembles Nuclei... with MPF) phosphorylates the lamin and is in- volved in the meiotic breakdown of the nuclear enve- lope... (NLD) by phosphorylating the nuclear lamins (Miake-Lye and ...

  

Source: Goldman, Robert D. - Department of Cell and Molecular Biology, Northwestern University

 

Collection: Biology and Medicine

 
98 between the nucleus and cytoplasm occurs through large macromolecular structures, the nuclear pores. Quantitative
 

Summary:  of the inner nuclear membrane protein LBR (a potential lamin B receptor) demonstrated that the inner and outer... a number of recently discovered inner nuclear membrane proteins, such as emerin, LAPs (lamin... 363 between the nucleus and cytoplasm occurs through large macromolecular structures, the ...

  

Source: Forbes, Douglass - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
99 INTRODUCTION Many cells have mechanisms to control the position of the
 

Summary:  -localized to the nuclear envelope with lamin and UNC-84. Unlike UNC- 84, UNC-83 localized to only specific nuclei, many... in nuclear migration (Gruenbaum et al., 2000). We examined lamin localization by immunofluorescence during... hyp7 nuclear migration in wild-type and unc-83(e1408) ...

  

Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT); Starr, Daniel A. - Section of Molecular and Cellular Biology, University of California, Davis

 

Collection: Biology and Medicine

 
100 GABAI'S ONE-SIDED LAMINATION It is well known that a properly embedded line in the plane separates the plane into two regions.
 

Summary:  GABAI'S ONE-SIDED LAMINATION It is well known that a properly embedded line in the plane separates... the plane into two regions. A measured lamination is an object which was introduced by Thurston which looks... locally like a Cantor set ×I. Gabai found a measured lamination in the plane whose complement is connected

  

Source: Agol, Ian - Department of Mathematics, Statistics, and Computer Science, University of Illinois at Chicago

 

Collection: Mathematics


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