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Sample search results for: aaa-atpase homologues determines

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1 An atomic model AAA-ATPase/20S core particle sub-complex of the 26S Friedrich Frster a,b
 

Summary:  for the a-subunits and 39­68% for the b subunits). Quaternary structure of AAA-ATPase­CP. To determine... ) determined the configuration of the AAA-ATPase subunits in the hexamer that are most consistent... /2/6/4/5/3) model. Configuration of the CP­AAA-ATPase sub-complex To ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
2 Structure and function of the membrane deformation AAA ATPase Vps4 Christopher P. Hill a,1
 

Summary:  Review Structure and function of the membrane deformation AAA ATPase Vps4 Christopher P. Hill a,1... mechanistic models of this ATPase. This article is part of a Special Issue entitled:AAA ATPases: structure... and function. Published by Elsevier B.V. 1. Introduction Vps4 is a type-1 AAA ...

  

Source: Hill, Chris - Department of Biochemistry, University of Utah

 

Collection: Biology and Medicine

 
3 Vacuolar Protein Sorting: Two Different Functional States of the AAA-ATPase Vps4p
 

Summary:  Vacuolar Protein Sorting: Two Different Functional States of the AAA-ATPase Vps4p Claudia Hartmann1... protein sorting (Vps) pathway, in which Vps4 class I AAA- ATPases play a central role, regulates growth... in a head-to-head--not in a head-to-tail-- fashion as in class II AAA-ATPases. Our model suggests

  

Source: de Groot, Bert - Max-Planck-Institut für biophysikalische Chemie

 

Collection: Biology and Medicine ; Biotechnology

 
4 CDC48/p97 is a conserved essential homohexameric AAA-ATPase chaperone involved in membrane fusion, protein degradation, and other cellular processes. We have
 

Summary:  i Abstract CDC48/p97 is a conserved essential homohexameric AAA-ATPase chaperone involved... , and differentiation. Studies in this thesis support that AtCDC48 is an essential AAA-ATPase chaperone that functions... 52 Figure 3. PUX1 interacts specifically with the CDC48/p97 class of AAA-ATPases 54 Figure 4. PUX1

  

Source: Bednarek, Sebastian Y. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
5 Cell cycle progression requires the CDC-48UFD 1/NPL 4 complex for efficient DNA replication
 

Summary:  in mammals), a chaperone-like AAA ATPase (1). Its activity is modulated by alternative adaptor proteins... regulator: Ubiquitin takes command of an AAA ATPase. J Struct Biol 156:29­40. 4. Meyer HH, Shorter JG... , Seemann J, Pappin D, Warren G (2000) A complex of mammalian ufd1 and npl4 links the ...

  

Source: Gartner, Anton - Wellcome Trust Centre for Gene Expression and Regulation, University of Dundee

 

Collection: Biology and Medicine

 
6 *Institute of Human Genetics, University of Goettingen, Goettingen, Germany Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India
 

Summary:  of spastin with known 3-D structure. The AAA ATPase domain of spastin was modeled on the basis... of spastin AAA domain. The tertiary structures of p97/VCP (a), VPS4B (b), and modeled AAA ATPase domain... domain of VPS4B is marked in green (b). The N-terminal beta strand (b¢) unique to meiotic ...

  

Source: Srinivasan, N. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
7 Cell, Vol. 119, 918, October 1, 2004, Copyright 2004 by Cell Press ReviewSculpting the Proteome with AAA
 

Summary:  of sub- strates influences their rates of unfolding by AAA ATPases and can determine whether a protein... Hughes Medical Institute plished at the level of substrate selection. Different AAA ATPases have distinct... , native protein substrates are bound by the ATPase, which then catalyzes ...

  

Source: Burton, Briana - Department of Molecular and Cellular Biology, Harvard University

 

Collection: Biology and Medicine

 
8 Toward an Integrated Structural Model of the 26S Proteasome*
 

Summary:  the AAA-ATPase dimer Rpt3/Rpt6. INTEGRATIVE STRUCTURE DETERMINATION OF THE RP Integrative methods... map and determined the rotation of the AAA-ATPase hexamer around its symmetry axis based on protein... data. These data allowed us to compute an atomic model for the CP-AAA-ATPase ...

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
9 THEJOURNALOFCELLBIOLOGY JCB VOLUME 172 NUMBER 4 2006486
 

Summary:  is a AAA ATPase with a ring structure at each head. VALE/ELSEVIER 10.1083/jcb.1724mr... ). Dynein, which is an AAA ATPase, differs both evolutionarily and structurally from kinesin and myosin... 8-nm steps. As rings on some AAA ATPases arrange in stacks, ...

  

Source: Reck-Peterson, Samara - Department of Cell Biology, Harvard University

 

Collection: Biology and Medicine

 
10 Yeast 2006; 23: 10531064. Published online in Wiley InterScience
 

Summary:  that associates with the AAA-ATPase p97 and is implicated in late steps in ER-associated protein degradation (ERAD... defines a new motif for interaction with this widely-employed AAA-ATPase. Copyright © 2006 John Wiley... for substrate retro- translocation. Numerous studies have implicated the hexameric AAA-ATPases, mammalian ...

  

Source: Hampton, Randy - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
11 Volume 22 February 1, 2011 291 The AAA-ATPase p97 is essential for outer
 

Summary:  Volume 22 February 1, 2011 291 The AAA-ATPase p97 is essential for outer mitochondrial membrane... that an AAA-ATPase, p97, is required for the proteasomal degradation of Mcl1 and Mfn1, two unrelated OMM... by the proteasome in the cytosol. p97 is ubiquitous and a member of the highly conserved AAA (ATPases ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
12 Membrane budding and scission by the ESCRT machinery: it's all in the neck
 

Summary:  of the class E VPS proteins include the Vps4 AAA+ ATPase, which provides the only direct energy input... -III disassembly A defining feature of the ESCRT pathway is the requirement for the AAA+ ATPaseVps4 to disassemble... similarly to other unfolding AAA+ ATPases as ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
13 Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin
 

Summary:  spas- tic paraplegias1 , and katanin are related microtubule-severing AAA ATPases2­6 involved... -severing AAA ATPases surround the entrances to the pore on either side of the ring, and three highly conserved... , and a carboxy-terminal AAA ATPase domain (Fig. 1a). ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
14 The Rockefeller University Press, 0021-9525/2000/07/F13/7 $5.00 The Journal of Cell Biology, Volume 150, Number 1, July 10, 2000 F13F19
 

Summary:  Pharmacology, University of California, San Francisco, California 94143 AAA ATPases (those associated... settings. Introduction AAA ATPases are not yet household words in the scien- tific community, although... of this superfamily (AAA, ATPase as- sociated with ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
15 Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4
 

Summary:  LETTERS Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4 Takayuki... and proteolysis1 . The AAA ATPase Vps4, which is central to endosomal traffic to lysosomes2,3 , retroviral budding... of an archaeal AAA ATPase of unknown function shows ...

  

Source: Williams, Roger L. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
16 The Arabidopsis AAA ATPase SKD1 Is Involved in Multivesicular Endosome Function and Interacts with Its
 

Summary:  The Arabidopsis AAA ATPase SKD1 Is Involved in Multivesicular Endosome Function and Interacts... of Colorado, Boulder, Colorado 80309-0347 In yeast and mammals, the AAA ATPase Vps4p/SKD1 (for Vacuolar... raised peptide antibodies against At-SKD1. Since >170 proteins in Arabidopsis contain ...

  

Source: Odorizzi, Greg - Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder

 

Collection: Biology and Medicine

 
17 Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains
 

Summary:  ). The motor domain of the heavy chain contains six predicted AAA [ATPase associated with various cellular... domains 4 and 5 (6, 7). Other AAA ATPases oligomerize into hexameric rings (4); however, dynein is unusual... (5). AAA domains 5 and 6 are highly divergent from other AAA ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
18 Characterization of AtCDC48. Evidence for Multiple Membrane Fusion Mechanisms at the Plane of Cell
 

Summary:  protein -SNAP, the AAA ATPase, NSF/Sec18p, binds stably to SNAREs form- ing a 20S complex (So¨llner et al... fusion and does not reconcile the many biochemical differences between these two AAA ATPases including... (Morgan et al., 1994; Meyer et al., 1998). Like other AAA ...

  

Source: Bednarek, Sebastian Y. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
19 Crenarchaeal CdvA Forms Double-Helical Filaments Containing DNA and Interacts with ESCRT-III-Like CdvB
 

Summary:  -III by the AAA ATPase Vps4. Nature 449: 735­739. 13. Saksena S, Sun J, Chu T, Emr SD (2007) ESCRTing proteins... EJ, Emr SD (1998) The Vps4p AAA ATPase regulates membrane association of a Vps protein complex... ) Three-dimensional structure of AAA ATPase Vps4: ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
20 The ER-associated degradation (ERAD) pathway directs ubiquitin-mediated degradation of a variety of ER-associated
 

Summary:  HMGR ubiquiti- nation and membrane extraction has not been determined, there are mammalian homologues... p, and exists in a complex with AAA-ATPase Cdc48p and Ufd1p Figure 1 Two ER-associated ubiquitin... in a few months of each other, place a new component, the Cdc48 AAA ATPase and its ...

  

Source: Hampton, Randy - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine


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21 In Planta Analysis of the Cell Cycle-Dependent Localization of AtCDC48A and Its Critical Roles
 

Summary:  , cytokinesis, and cell fate determination. DISCUSSION AtCDC48A Has Multiple Roles during Development The AAA-ATPase... homohexameric AAA-ATPase chaperone required for a variety of cellular processes but whose role... ; Davies et al., 2005). The conservation and wide- spread use of the AAA domain suggests that ...

  

Source: Bednarek, Sebastian Y. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
22 Unraveling the early steps of prokaryotic replication Erin L Cunningham and James M Berger
 

Summary:  # 2005 Elsevier Ltd. All rights reserved. DOI 10.1016/j.sbi.2005.01.003 Abbreviations AAA+ ATPase... to the remodeling events required for origin unwinding and replisome assembly. AAA+ ATPase domains as molecular... superfamily of AAA+ (ATPase Associated with various ...

  

Source: Berger, James M. - Department of Molecular and Cell Biology, University of California at Berkeley

 

Collection: Biology and Medicine

 
23 MolecularandCellularBiology,December2001,p.8035-8044,Vol.21,No.23 Identification of Components of the Murine Histone
 

Summary:  ), as well as the homologue of yeast Cdc48p AAA ATPase (p97/VCP/Cdc48p) (11). The UFD pathway was discovered... proteins involved in Ub-dependent protein degradation. The first one, p97/VCP/Cdc48p, an AAA-ATPase... . A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
24 Many plasma-membrane proteins are in a constant flux throughout the internal trafficking pathways of
 

Summary:  are disassembled by the AAA+ ATPase Vps4. Budding away from the cytosol is depicted as being facilitated... ,76). Importantly, multiple ESCRT-III-related proteins bind to the MIT domain of the AAA+ ATPase Vps4 (REFS 79... % identical yeast Vps4 (REF. 102). These enzymes belong to a subset of ...

  

Source: Williams, Roger L. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine

 
25 Characterization of Two Subunits of Arabidopsis 19S Proteasome Regulatory Complex and its Possible
 

Summary:  complex (Ohana et al., 1993). The three distinctive struc- tural motifs of AtS6A (and other AAA ATPases... . (b) Structural features of the AAA-family of proteasomal ATPases. The AAA ATPase family of genes... complex subunit 9; HTH, helix-turn-helix; ORF, open reading frame; EST, expressed sequence tag; ...

  

Source: Deng, Xing-Wang - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine ; Biotechnology

 
26 Insights into the molecular architecture of the 26S proteasome
 

Summary:  spectrometry. ATPase cryo-electron microscopy mass spectrometry protein degradation AAA-ATPase Cellular protein... of the RP, namely the AAA-ATPase, within our reconstruction. Our procedure is based on the assumption... that the ATPase subunits Rpt1­6 form a hexameric complex like most other AAA-ATPases. In fact, slices through

  

Source: Sali, Andrej - Department of Biochemistry and Biophysics, University of California at San Francisco

 

Collection: Biology and Medicine ; Biotechnology

 
27 The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein
 

Summary:  , chromista and plants [9], possess homologues of the AAA+ ATPase, Hsp104. Hsp104 collaborates with Hsp70... 104, a AAA+ ATPase that collaborates with Hsp70 and Hsp40 to promote protein disaggregation... activity, which can be accelerated and stimulated by Hsp104. This activity did not ...

  

Source: Shorter, James - Department of Biochemistry and Biophysics, University of Pennsylvania

 

Collection: Biology and Medicine

 
28 Characterization of Aspergillus nidulans DidBDid2, a non-essential component of the multivesicular body pathway
 

Summary:  factors like Did2 recruits the AAA ATPase Vps4 that disassembles the complex and releases its components... binding to the MIT domain in the Vps4 AAA ATPase with micromolar affinity (Nickerson et al., 2006... , respectively, interact directly with Vps4, the AAA ATPase ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
29 Molecular Biology of the Cell Vol. 21, 10591071, March 15, 2010
 

Summary:  Molecular Biology of the Cell Vol. 21, 1059­1071, March 15, 2010 Assembly of the AAA ATPase Vps4... is an AAA (ATPase associated with various cellular activities)- type ATPase that releases ESCRT-III from... correspondence to: Markus Babst (babst@biology.utah.edu). Abbreviations used: ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
30 Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation*S
 

Summary:  . Dyneins are AAA ATPases, a superfamily of enzymes that have a diverse array of functions ranging from... , AAA ATPases all share a similar core architecture with conserved Walker-A (P loop) and Walker... camera every 2 s for 5­10 min. Velocities and run lengths were determined by kymo- ...

  

Source: Reck-Peterson, Samara - Department of Cell Biology, Harvard University

 

Collection: Biology and Medicine

 
31 Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation*S
 

Summary:  . Dyneins are AAA ATPases, a superfamily of enzymes that have a diverse array of functions ranging from... , AAA ATPases all share a similar core architecture with conserved Walker-A (P loop) and Walker... camera every 2 s for 5­10 min. Velocities and run lengths were determined by kymo- ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
32 Tunicates and not cephalochordates are the closest living relatives of vertebrates
 

Summary:  b 241 nsf1-E Vacuolar protein sorting factor, paraplegin-like protein 303 nsf1-G 26S proteasome AAA-ATPase... regulatory subunit 8 253 nsf1-H AAA-ATPase family protein CDC48-like protein 173 nsf1-I putative 26S... proteasome ATPase regulatory subunit 7 273 nsf1-J 26S proteasome AAA-ATPase regulatory subunit 6 352 nsf1-K

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
33 Plant UBX Domain-containing Protein 1, PUX1, Regulates the Oligomeric Structure and Activity of Arabidopsis CDC48*
 

Summary:  -Madison, Madison, Wisconsin 53706 p97/CDC48 is a highly abundant hexameric AAA- ATPase that functions... -262-3453; E-mail: bednarek@ biochem.wisc.edu. 1 The abbreviations used are: AAA, ATPase associated... member of the AAA ATPase, the N-ethylmaleimide-sensitive ...

  

Source: Bednarek, Sebastian Y. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
34 Published online 27 May 2009 Nucleic Acids Research, 2009, Vol. 37, No. 13 44414452 doi:10.1093/nar/gkp376
 

Summary:  other proteins in the AAA ATPase superfamily and likely participate in the unwind- ing reaction (17... /min/mol of enzyme in the absence of DNA (Figure 5). We note that ATP is hydrolyzed in AAA+ ATPases at subunit... are AAA+ ATPases and consequently their activity is ...

  

Source: Chait, Brian T. - Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University

 

Collection: Biology and Medicine

 
35 Automation for Cryo-TEM: From Specimen Grid to 3D
 

Summary:  AAA ATPase p97), spherical viruses (NWV) and helical filaments (tobacco mosaic virus). Data from... . These include identifying suitable areas of vitreous ice at low magnification, determining the presence

  

Source: Scripps Research Institute, Department of Cell Biology, Automated Molecular Imaging Group

 

Collection: Chemistry ; Biology and Medicine

 
36 Molecular Biology of the Cell Vol. 21, 33963408, October 1, 2010
 

Summary:  , enveloped virus budding, and membrane abscission during cytokinesis. The AAA-ATPase Vps4 is required... ., 2009; Hanson et al., 2009). Vps4 is a type 1 AAA- ATPase that contains an amino-terminal Microtubule... cofactor Vta1, by mutation of the Vps4 central pore, and by analogy to other AAA-ATPases (Scott et ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
37 Cdc48Ufd1Npl4: Stuck in the Middle with Ub
 

Summary:  . 147, 45­58. 24. Ye, Y., Meyer, H.H. and Rapoport, T.A. (2001). The AAA ATPase Cdc48/p97 and its... ., Frohlich, K.U., Diamant, N. and Bar-Nun, S. (2002). AAA-ATPase p97/Cdc48p, a cytosolic chaperone required... requires polyubiquitination and the AAA-ATPase Cdc48. Nat Cell Biol. 4, 134-139. 27. Hua, X., ...

  

Source: Hampton, Randy - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
38 The endosomal system is a major membrane-sorting apparatus. New evidence reveals that novel coat proteins assist specific
 

Summary:  ) [2,26­28,35] Vam3p Syntaxin-related Vacuolar t-SNARE [2,11,23,39] Vps4p Mm SKD1, Hs VPS4 AAA ATPase... . One class E regulatory protein, Vps4p, is a member of the AAA ATPase family. It cycles onto membranes... - phatidylinositol 3-phosphate (PtdIns(3)P), Vps45p, an endosomal Sec1p ...

  

Source: Traub, Linton M. - Department of Cell Biology and Physiology, University of Pittsburgh

 

Collection: Biology and Medicine

 
39 Current Biology, Vol. 15, 650655, April 12, 2005, 2005 Elsevier Ltd All rights reserved. DOI 10.1016/j.cub.2005.02.029 The Drosophila Homologue of the
 

Summary:  in the spastin gene, active for disassembling cytoplasmic microtubules (Fig- which encodes a AAA+ ATPase [1, 2... interacting and trafficking domain; and AAA, AAA+ ATPase domain. The positions of disease mutations (S462C, K... be expected on the basis of their other AAA+ ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
40 Molecular Biology of the Cell Vol. 20, 35143524, August 1, 2009
 

Summary:  . The AAA-ATPase Vps4 catalyzes disassembly of the ESCRT-III complex and may regulate membrane deformation... , the AAA ATPase Vps4 and associated regu- lators of these proteins (Williams and Urbe, 2007; Hurley, 2008... determined the crystal structure of the N-terminal domain of Ist1 (Ist1NTD) and examined ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine


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41 Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations
 

Summary:  for recruiting the AAA+ ATPase VPS4, required for disassembly and recy- cling of ESCRT-III subunits... -1 with itself, membranes, and the AAA+ ATPase SKD1. J. Biol. Chem., 280, 12799­12809. 24. Whitley, P., Reaves, B... .D. and Williams, R.L. (2007) Structural basis for selective recognition of ESCRT-III by ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
42 JOURNAL OF VIROLOGY, Dec. 2007, p. 1363113639 Vol. 81, No. 24 0022-538X/07/$08.00 0 doi:10.1128/JVI.01688-07
 

Summary:  AAA ATPase believed to be required late in the MVB pathway for the disassembly/release of the MVB... - uitin recognition. A late step in the MVB pathway involves the recruitment of VPS4, an AAA ATPase... . 2004. Distinct roles for the AAA ATPases NSF and p97 in the ...

  

Source: Kielian, Margaret - Department of Cell Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
43 Services provided by the Biophysics Resource contributed to at least 63 publications (40 from Yale)
 

Summary:  .(2004) "The AAA ATPase p97/VCP Interacts with Its Alternative Co-factors, Ufd1-Npl4 and p47, through... -Stogniew and K.R. Williams (1999) "Determination of molecular masses of protein: implementation of a size... 280; 23280-23286 21. Folta-Stogniew, E.(2006) "Oligomeric States of Proteins Determined by Size

  

Source: Engelman, Donald M.- Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
44 Molecular Biology of the Cell Vol. 17, 10751084, March 2006
 

Summary:  complex is biologically relevant. To determine whether the binding was direct or mediated by other factors... to determine whether WldS protein, or N70 can interfere with the effect of VCP in any

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
45 Endoplasmic reticulum architecture: structures in flux Nica Borgese1,2
 

Summary:  . cerevisiae Cdc48, an AAA ATPase with homology to the well-characterized fusion protein N- ethylmaleimide... -Cortes D, Warren G, Mattaj IW: Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear... . In this review, we will discuss recent work on the factors that determine the formation of ...

  

Source: Snapp, Erik Lee - Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
46 # 2007 The Authors doi: 10.1111/j.1600-0854.2007.00660.x
 

Summary:  data10 ) (Figure 2, step 8). Orthologues of ClpC, an AAA ATPase chaperone implicated as the motor... . The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 2001... of the primary plastid. No Toc homologues can be found, and no strong leads ...

  

Source: McFadden, Geoff - School of Botany, University of Melbourne

 

Collection: Environmental Sciences and Ecology

 
47 The elusive middle domain of Hsp104 and ClpB: Location and function Morgan E. DeSantis a,b
 

Summary:  Issue entitled: AAA ATPases: structure and function. © 2011 Elsevier B.V. All rights reserved. 1... of proteins [1­9]. This family, in turn, is a member of the AAA+ (ATPases Associated with various cellular... . Biochimica et Biophysica Acta xxx (2011) xxx­xxx This article is part of a Special Issue ...

  

Source: Shorter, James - Department of Biochemistry and Biophysics, University of Pennsylvania

 

Collection: Biology and Medicine

 
48 Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution
 

Summary:  B, dus and sun), protein turnover (clpS, and an AAA ATPase family gene), stress responses (umuD and pho... by the phage. Many of these host genes are located in genome islands and have homologues in cyanophage genomes... phage DNA) and length of the lytic cycle (extracellular phage DNA) was determined by ...

  

Source: Church, George M. - Wyss Institute for Biologically Inspired Engineering & Department of Genetics, Harvard University; Futschik, Matthias E. - FachInstitut Theoretische Biologie, Humboldt-Universität zu Berlin

 

Collection: Biology and Medicine ; Biotechnology

 
49 INTRODUCTION Proteins must mature to their native confor-
 

Summary:  the ubiquitination enzymes E2 and E3 (5). The AAA-ATPase p97 hexameric ring is believed to provide the energy... . In yeast and mammals, the hexameric AAA-ATPase p97/Cdc48, identified in mouse and yeast, respectively... , functions in a complex with Ufd1 and Npl4 (114,115). Both the mam- malian and yeast AAA-ATPase have been

  

Source: Hebert, Daniel N. - Department of Biochemistry and Molecular Biology, University of Massachusetts at Amherst

 

Collection: Biology and Medicine

 
50 The nuclear envelope: form and reformation Amy J Prunuske and Katharine S Ullman
 

Summary:  , but is likely to share many components with the ER lumen. Recent studies focused on the AAA+ ATPase torsin... 97, a hexameric AAA+ ATPase, was first implicated in ER and Golgi vesicle fusion [44]. In conjunction... , Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW: Distinct AAA-ATPase ...

  

Source: Ullman, Katie - Huntsman Cancer Institute, University of Utah

 

Collection: Biology and Medicine

 
51 Introduction The proteasome is crucial to many cellular processes. Most
 

Summary:  changes in the AAA-ATPase ring of the RP that facilitates lid binding and other aspects of RP function... the AAA ATPase p97/VCP and its adaptor protein p47. EMBO J. 23, 1030-1039. Elsasser, S., Gali, R. R... that suppressed Dsk2-mediated lethality were cloned by gap- repair and the mutations were determined ...

  

Source: Hochstrasser, Mark - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
52 Classification of ATP-dependent proteases Lon and comparison of the active sites of their proteolytic domains
 

Summary:  and structural variation of Lon subfamilies According to the evolutionary classification of the AAA+ ATPases [7... , E.V. & Aravind, L. (2004) Evolutionary history and higher order classification of AAA+ ATPases. J... confirmed by site-directed mutagenesis of the Escherichia coli Lon protease and by ...

  

Source: Wlodawer, Alexander - Macromolecular Crystallography Laboratory, National Cancer Institute

 

Collection: Chemistry ; Biology and Medicine

 
53 Introducing a third domain of life In the late fifties Francis Crick proposed to classify and organize the living organisms based on a
 

Summary:  in eukaryotes (Fig. 1). This method of determining the taxonomic position of organisms is valid until today (Fox... -binding protein, homologue of eTBP), and TFB (transcription factor B ­ homologue of eTFIIB). Archaeal promoters... homologue is responsible for recognition of a TATA-box, which is the ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
54 letters to nature NATURE |VOL 403 |17 FEBRUARY 2000 |www.nature.com 795
 

Summary:  ). To determine whether the mouse Sir2 homologue mSir2a would catalyse this deacetylation reaction, we incubated... -ethylmaleimide- sensitive fusion protein10,11 , the prototype of an AAA-ATPase. A third, mostly a-helical domain in Hsl... in proteasomal AAA-ATPases. We expressed and puri®ed histidine-tagged ...

  

Source: Guarente, Leonard P. - Department of Biology, Massachusetts Institute of Technology (MIT)

 

Collection: Biology and Medicine

 
55 The large size and complex organization of eukaryotic cells necessitates active, directional transport for the
 

Summary:  domain 1 2 3 4 5 6 RZZ C AAA+ ATPase (ATPase associated with various cellular activities). A large family... proteins and complexes. AAA+ ATPases contain one or two characteristic ATP-binding domains, with additional... is a member of the ATPase associated with various cellular activities ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
56 ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular
 

Summary:  recruits Vps2, which in turn recruits the Vps4 AAA­ATPase complex to disassemble ESCRT-III before MVB... the recruitment of the Vps4 AAA­ATPase, which then initiates the disassembly of ESCRT-III (Obita et al, 2007... -III determines how MVB vesicles are formed. The first indication came from over- expression of hSnf7/hVps32 ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
57 The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome
 

Summary:  homologues and an estimate of crossing- over frequency during genetic exchange. Genetic polymorphisms... and chromosome analysis The DNA sequence of chromosome I was determined by whole chromosome shotgun (WCS). Brie... ¯y, the faster migrating homologue (chrIa) was excised and eluted from pulsed ®eld gels (PFGs), sheared

  

Source: Schnaufer, Achim - Institute of Immunology and Infection Research, University of Edinburgh

 

Collection: Biology and Medicine

 
58 UNIVERSITE JOSEPH FOURIER GRENOBLE I UFR DE BIOLOGIE
 

Summary:  des activités de type chaperonne moléculaire. Elles appartiennent à la large famille des AAA+ (ATPase... 4). La famille des AAA+ (ATPase Assoicated with Various Cellular Activities) regroupe un grand... .1 VAT : homologue fonctionnel de PAN chez Thermoplasma acidophilum 42 V.3 Rôle et ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
59 ATPase Thorase Regulates AMPA Receptor-Dependent Synaptic
 

Summary:  The AAA+ ATPase Thorase Regulates AMPA Receptor-Dependent Synaptic Plasticity and Behavior Jianmin... in learning and memory are still being revealed. Here we describe and characterize the AAA+ ATPase Thorase... as deficits in learning and memory in Thorase null mice. This study identifies an ...

  

Source: Blackshaw, Seth - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
60 Structure and Disassembly of Filaments Formed by the ESCRT-III Subunit Vps24
 

Summary:  by the MIT-interacting motif from the Vps2 subunit of ESCRT-III, the AAA- ATPase Vps4 can both bundle... . The AAA-ATPase Vps4 catalyzes the dissociation of the ESCRT machinery from endosomal mem- branes... /E)xxLxxRLxxL(K/R) that is recognized by the N-terminal microtubule-interacting and transport (MIT) domain of Vps4, the ...

  

Source: Williams, Roger L. - Laboratory of Molecular Biology, MRC

 

Collection: Biology and Medicine


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61 Automated Image Acquisition for Single-Particle Reconstruction Using p97 as the Biological Sample
 

Summary:  , to collect data of single particles, specifically of the AAA ATPase p97. The images were acquired under low... ATPase is a member of the large AAA ATPase family (for ATPases Associated with differ- ent cellular... role of the AAA ATPases in many cellular pathways ...

  

Source: Scripps Research Institute, Department of Cell Biology, Automated Molecular Imaging Group

 

Collection: Chemistry ; Biology and Medicine

 
62 Systematic functional analysis of the Caenorhabditis elegans
 

Summary:  ............................................................................................................................................................................. Nonv and Gro G-protein b-subunit WD40 repeat AAA ATPase KH domain Zinc-finger, C-X8-C-X5-C-X3-H type... , because more than half of the genes in C. elegans have a human ...

  

Source: Ahringe, Julie - Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge; Hahn, Mark E. - Biology Department, Woods Hole Oceanographic Institution

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
63 Prediction of Interface Residues in ProteinProtein Complexes by a Consensus Neural Network Method: Test
 

Summary:  with the AAA ATPase protein p9740 and the HP1 chromo domain with histone H3,41,42 have recently been determined... identified the interaction surface of the C-terminal domain of the adaptor protein p47 with the AAA ATPase

  

Source: Weston, Ken - Department of Chemistry and Biochemistry, Florida State University

 

Collection: Chemistry

 
64 8th International Meeting on Yeast Apoptosis 1509 Mitochondrial quality control by the
 

Summary:  -stress-responsive 1 (Vms1). Abbreviations used: AAA, ATPase associated with various cellular activities; ERAD, ER... is conserved throughout eukarya. During ER stress, the AAA ATPase Cdc48 (cell division cycle 42)/p97... ) The AAA ATPase Cdc48/p97 and its partners ...

  

Source: Rutter, Jared - Department of Biochemistry, University of Utah

 

Collection: Biology and Medicine

 
65 Copyright C Blackwell Munksgaard 2002 Traffic 2002; 3: 621629
 

Summary:  are enzymatically disassembled by the AAA (ATPases associated with various cellular activities) (67) chaperone NSF... SNAREs for fusion (44). A second AAA ATPase, CDC48 (p97 in mammalian cells) has also been shown... in plant cells. For #12;Membrane Trafficking During Plant Cytokinesis example, it remains to ...

  

Source: Bednarek, Sebastian Y. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
66 Genome Biology 2009, 10:R70 Open Access2009Zivanovicet al.Volume 10, Issue 6, Article R70Research
 

Summary:  the genes with a functional assignment in T. kodaka- raensis KOD1, only those coding for a predicted AAA-ATPase... . Moreover, 8 out of the 14 genes found in tgv2 are predicted to encode proteins of known function: 3 AAA-ATPase... (b). (a) (b) attL intC (tg1617) attR intN (tgam13283) tRNAArg3 1.520.320 AAA ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
67 TheJournalofCellBiology The Rockefeller University Press, 0021-9525/2004/04/41/12 $8.00
 

Summary:  of the lesion is the most important determinant. Membrane pro- teins with lesions in their cytosolic domains... ). This suggests that the site of lesion with respect to the ER membrane could be a major determinant... folded and misfolded domains. The site of lesion determines the pathway used First, we analyzed

  

Source: Shorter, James - Department of Biochemistry and Biophysics, University of Pennsylvania

 

Collection: Biology and Medicine

 
68 Sequence-based and structure-based phylogeny 83 J. Biosci. 32(1), January 2007
 

Summary:  phylogeny but it is evident in the structure-based phylogeny. (vii) Extended AAA ATPase domain... is usually good if the sequence similarity among the homologues is about 30% or more. For protein families... structures if the sequence similarities (SSM) of the homologues are very low. [Balaji S and ...

  

Source: Srinivasan, N. - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
69 Protein Domain-Domain Interactions and Requirements for the Negative Regulation of Arabidopsis CDC48/p97 by the
 

Summary:  is an essential AAA-ATPase chaperone that functions in numerous diverse cellular activities through its... of the Arabidopsis CDC48/p97 ortholog, AtCDC48, as well as mammalian p97 but not the related AAA ATPase N... was determined by SDS- PAGE and Coomassie Blue staining.4 D. M. Rancour and S. Y. Bednarek, ...

  

Source: Bednarek, Sebastian Y. - Department of Biochemistry, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
70 Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
 

Summary:  is then ubiquitinated by PEX4 and retro-translocated out of the bilayer by the action of an AAA- ATPase complex... the above- mentioned AAA-ATPase complex (e.g., PEX1, PEX6, and/or PEX26). Interestingly, pexophagy... interactions with ubiquitin-binding proteins (24). To determine whether this patch is also ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
71 Molecular Cell Cdc48/p97 Mediates UV-Dependent
 

Summary:  protein complexes. INTRODUCTION Budding yeast Cdc48 is a member of the AAA (ATPases associ- ated... . (2009). A conserved unfoldase activity for the p97 AAA-ATPase in proteasomal degradation. J. Mol. Biol... 4, e5267. Cheng, Y.L., and Chen, R.H. (2010). The AAA-ATPase Cdc48 and cofactor Shp1 promote

  

Source: Deshaies, Raymond J. - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
72 The Rockefeller University Press $30.00 J. Cell Biol. Vol. 189 No. 6 945954
 

Summary:  ., 2005; Roll-Mecak and Vale, 2005), which belong to the family of AAA ATPases. One structural model of MT... , and F.J. McNally. 1998. Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets... . Statistical significance was determined by two-tailed Student's t test. ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
73 JOURNAL OF VIROLOGY, July 2010, p. 65906597 Vol. 84, No. 13 0022-538X/10/$12.00 doi:10.1128/JVI.00035-10
 

Summary:  components include ALIX, which interacts both with ESCRT-I and ESCRT-III, and the AAA ATPase Vps4, which... , membranes, and the AAA ATPase SKD1. J. Biol. Chem. 280:12799­12809. 37. Ma, Y. M., and V. M. Vogt. 2004... that the ESCRT pathway dependence of HIV-1 budding is determined, at ...

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
74 Recombinant Expression, Purification, and Comparative Characterization of TorsinA and Its Torsion Dystonia-Associated Variant E-TorsinA
 

Summary:  proteins are 25-30% identical to several members of the HSP/Clp subclass of AAA ATPases over a 140-amino... .4 mL, 2.5 mg of protein/mL) was loaded onto the gel filtration column 1 Abbreviations: AAA: ATPases... the C-terminus of torsinA (Glu302/303; E- torsinA). Human torsin proteins have clear ...

  

Source: Cravatt, Benjamin - Department of Cell Biology, Scripps Research Institute

 

Collection: Biology and Medicine

 
75 Molecular Cell Heterohexameric Ring Arrangement
 

Summary:  to determine the quaternary arrangement of the six paralogous proteasomal AAA+ ATPase subunits in yeast (Fig... or two regulatory particles (RPs). Each RP is believed to include six different AAA+ ATPases... et al., 2009; Finley, 2009). The base includes six paralogous ...

  

Source: Hochstrasser, Mark - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine

 
76 General introduction Introduction
 

Summary:  -essential Pdi1p homologues have been found, Eug1p, Mpd1p, Mpd2p and Eps1p. All these PDI homologues... homologue that could restore cell viability in a strain completely depleted of other Pdi1p like proteins... that the specificity of vesicle targeting is not exclusively determined by the SNARE complexes ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
77 Move it on over: getting proteins across biological membranes
 

Summary:  . Ye Y, Meyer HH, Rapoport TA. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER... a translocation pathway of a size determined by the size of the transiting cargo. Following translocation... , this pathway, relying on a translocon based on the TatA-E subunits (or their thylakoid ...

  

Source: Eichler, Jerry - Department of Life Sciences, Ben-Gurion University

 

Collection: Biology and Medicine

 
78 INTRODUCTION Dystonia is a movement disorder characterized by involuntary
 

Summary:  AAA+ (ATPases associated with cellular activity) family of ATPase proteins. Several AAA+ proteins... was performed in worms expressing Q82 + WT torsinA to determine whether they could enhance WT torsinA activity... hurdles prior to the onset of human trials. It also needs to be determined whether, in cells ...

  

Source: Caldwell, Guy - Department of Biological Sciences, University of Alabama in Tuscaloosa

 

Collection: Biology and Medicine

 
79 Research Paper Selective chemical inactivation of AAA proteins reveals distinct
 

Summary:  that di¡erent AAA ATPases in the 19S complex have di¡erent activities it is necessary to ablate... by a comparison be- tween two AAA ATPases which are functional orthologs. NSF is a AAA protein involved... ]. In addition there are six di¡erent, yet highly similar, AAA ...

  

Source: Joshua-Tor, Leemor - W. M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory

 

Collection: Biology and Medicine

 
80 The Saccharomyces cerevisiae genome sequence, augmented by new data on gene expression and function, continues to
 

Summary:  .7 Ubiquitin-conjugating proteins 24 8.3 Proteasome subunits 34 2.9 Serine-rich proteins 10 0.0 AAA ATPase... expression was a significant factor determining which genes were retained as duplicates and which were... ­J represent genes, with different fonts used to distinguish between homologues. For ...

  

Source: Wolfe, Kenneth H. - Genetics Department, Trinity College, University of Dublin

 

Collection: Biotechnology ; Environmental Sciences and Ecology


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81 Molecular Cell CDC-48/p97 Coordinates CDT-1 Degradation
 

Summary:  for the ubiquitin ligase CRL4Cdt2. Mol. Cell 35, 93­104. Heubes, S., and Stemmann, O. (2007). The AAA-ATPase p97-Ufd... from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat. Cell Biol. 4, 134­139. Jia, L... ­1767. Rabinovich, E., Kerem, A., Fro¨ hlich, K.U., Diamant, N., and Bar-Nun, S. (2002). AAA-ATPase ...

  

Source: Gartner, Anton - Wellcome Trust Centre for Gene Expression and Regulation, University of Dundee

 

Collection: Biology and Medicine

 
82 THEJOURNALOFCELLBIOLOGY JCB: COMMENT
 

Summary:  , belonging to the AAA ATPase family and a regu- latory subunit, p80) was named katanin, after the Japanese... homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules. Curr

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
83 In Press: Current Opinion in Genetics and Development (2009) Improving the chances of finding the right partner
 

Summary:  sites exist, which determine homologue recognition and from which synapsis is initiated... , that adequately explains the mechanism of this process in a quantitative way. The fact that homologue pairing... eukaryotic species carry two copies (homologues) of each chromosome ­ one derived from each parent. A ...

  

Source: Shaw, Peter - Cell and Developmental Biology Department, John Innes Centre

 

Collection: Biology and Medicine

 
84 Identification of the Protein Targets of the Reactive Metabolite of Teucrin A in Vivo in the Rat
 

Summary:  .0, at 4 °C. Protein concentrations were determined by BCA assay (Pierce). Western Analysis Using 2I2 Sc... that false discovery rates could be determined, and the reversed version of each protein sequence... considered for the analysis. Fischer's exact test was used to calculate a p value determining the probability

  

Source: Marnett, Lawrence J. - Department of Chemistry, Vanderbilt University

 

Collection: Biology and Medicine ; Chemistry

 
85 The many faces of the helix-turn-helix domain: Transcription regulation and beyond q
 

Summary:  found fused to the HTH in the LevR-subfamily with the NtrC-type AAA+ ATPases PTSIIA a + b ­ A conserved... K­HerA superfamily ATPase domain [73] in bacterial chromosome pumping protein FtsK [74], or the AAA+ ATPase domain... , and this motif was shown to be a critical determinant of ...

  

Source: Babu, M. Madan - Laboratory of Molecular Biology, MRC

 

Collection: Biotechnology

 
86 DOI: 10.1126/science.1200037 , 1154 (2011);331Science
 

Summary:  family of ATPases (2). The AAA ATPases (ATPases associated with diverse cellular activities), which... , 5). Dynein is one of two AAA ATPases that has six distinct AAA do- mains concatenated within... to other AAA ATPases (7­9). 1 Department of Cellular and Molecular ...

  

Source: Juelicher, Frank - Max-Planck-Institut für Physik komplexer Systeme

 

Collection: Biology and Medicine ; Physics

 
87 The Affinity of the Dynein Microtubule-binding Domain Is Modulated by the Conformation of Its Coiled-coil Stalk*S
 

Summary:  -binding domain (MTBD) of dynein is separated from the AAA (ATPase with any other activ- ity) core of the motor... are: AAA, ATPase with any other activity; CC1 and CC2, coiled-coil strands on the N-terminal and C... , comprises a ring of six AAA ATPase domains, ...

  

Source: Reck-Peterson, Samara - Department of Cell Biology, Harvard University

 

Collection: Biology and Medicine

 
88 The Affinity of the Dynein Microtubule-binding Domain Is Modulated by the Conformation of Its Coiled-coil Stalk*S
 

Summary:  -binding domain (MTBD) of dynein is separated from the AAA (ATPase with any other activ- ity) core of the motor... are: AAA, ATPase with any other activity; CC1 and CC2, coiled-coil strands on the N-terminal and C... , comprises a ring of six AAA ATPase domains, ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine

 
89 YEAST VOL. 14: 409417 (1998) Identification and Analysis of Homologues of
 

Summary:  strands. Cloning an S. pombe SPT3 homologue Based on the homology determined by align- ment of the K... functional domains. Functional analysis of SPT3 homologues To determine if these SPT3 homologues were also... . To determine if complementation by each of the ...

  

Source: Winston, Fred - Department of Genetics, Harvard University

 

Collection: Biology and Medicine

 
90 Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex
 

Summary:  of the initiator clade of AAA+ ATPases30 and is absent in other AAA+ assemblies, such as the eukaryotic clamp... classification of AAA+ ATPases. J. Struct. Biol. 146, 11­31 (2004). 31. Bowman, G.D., O'Donnell, M. & Kuriyan, J... of the regulatory and AAA+ ATPase ...

  

Source: Leschziner, Andres - Department of Molecular and Cellular Biology, Harvard University

 

Collection: Biology and Medicine

 
91 S1Supplementary material A gain-of-function screen for genes controlling motor axon
 

Summary:  two hemisegments per larva showed errors in To determine the relationships between the predicted genes... . Tatei K, Cai H, Ip YT, Levine M: Race: a Drosophila homologue S21. Simon MA, Dodson GS, Rubin GM: An SH3... : Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 andS36. Inoue YH, Avides MD

  

Source: Zinn, Kai - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
92 Journal of Molecular Graphics and Modelling 29 (2010) 573580 Contents lists available at ScienceDirect
 

Summary:  of Hfq with three known examples of AAA+ ATPases (a) HslUV, (b) p97, (c) T antigen and (d) Hfq. known AAA... to that of the known AAA+ ATPases (Fig. 1). Using a combination of biochemical and genetic techniques, a plausible ATP... -binding protein. They determined a ...

  

Source: Lee, Keun Woo - Department of Biochemistry, Gyeongsang National University

 

Collection: Biotechnology ; Biology and Medicine

 
93 Drosophila Spastin Regulates Synaptic Microtubule Networks
 

Summary:  (spastin) gene, which encodes an AAA ATPase closely related in sequence to the microtubule-severing protein... by mutations in the SPG4 gene, which encodes an AAA ATPase called Spastin (Hazan et al. 1999). AAA ATPases... vesicle trafficking, protein degradation, and ...

  

Source: Zinn, Kai - Division of Biology, California Institute of Technology

 

Collection: Biology and Medicine

 
94 260 trends in CELL BIOLOGY (Vol. 8) July 1998 A model for
 

Summary:  . et al. (1998) Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets... with syntaxin homologues on intracellular organelles. In some cases, evidence suggests that more than one v... of SNAP-25 homologues and the pres- ence of more than one v-SNARE in intracellular SNARE complexes

  

Source: Weimbs, Thomas - Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara

 

Collection: Biology and Medicine

 
95 The Dynamic Cell 1007 Regulation of microtubule dynamic instability
 

Summary:  mechanism depends on severing proteins such as spastin and katanin, the AAA (ATPase associated with various... knowledge about factors modulating MT dynamic instability (see Figure 1). MT dynamics is determined largely... -binding) 1, EB3 and the fission yeast homologue Mal3 allow persistent MT growth in ...

  

Source: Marie Curie Research Institute, Molecular Motors Group

 

Collection: Biology and Medicine

 
96 Chapter 1 An introduction to adenine nucleotidebinding proteins Adenosine triphosphate
 

Summary:  is related to the AAA ATPases. The domains present in addition to the NTPase units usually... ,L. (2004) Evolutionary history and higher order classification of AAA+ ATPases. J Struct Biol, 146... (ATPases associated with a variety of cellular activities). Several other members of ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
97 q 2001 International Society for Neurochemistry, Journal of Neurochemistry, 77, 14071417 1407 Journal of Neurochemistry, 2001, 77, 14071417
 

Summary:  homologous to domains in a large group of proteins of diverse function, collectively classi®ed as AAA ATPases... @sickkids.on.ca Abbreviations used: AAA, ATPases associated with diverse activ- ities; ECL, enhanced chemiluminescence; NSF, N... cerevisiae AAA ATPase ...

  

Source: Stewart, Bryan - Department of Biology, University of Toronto at Mississauga

 

Collection: Environmental Sciences and Ecology

 
98 AR REVIEWS IN ADVANCE10.1146/annurev.cellbio.18.032002.131219 (Some corrections may occur before final publication online and in print)
 

Summary:  remains unclear. So far, the subcellular location of S2P has not been unambiguously determined (M. Brown... agent. The identity of the non-sterol signal remains to be determined, but clearly FPP is important... ), and the extent of this process is determined by the degree to which ApoB escapes degradation by successful

  

Source: Hampton, Randy - Division of Biological Sciences, University of California at San Diego

 

Collection: Biology and Medicine

 
99 Original Article Exploration of the extracellular space by a large-scale
 

Summary:  /ER/Golgi Cathepsin D Asp protease 2 vG, dG DN828613 TER-ATPase AAA ATPase Vesicle formation 7 vG DN828614 prenylated... (TER ATPase), a member of the AAA (ATPases associ- ated with a variety of cellular activities) protein... Serpin Chaperone 1 dG Mouse DN828629 Torsin B AAA ...

  

Source: De Robertis, Eddy M. - Department of Biological Chemistry, University of California at Los Angeles

 

Collection: Biology and Medicine

 
100 DOI: 10.1126/science.1202393 , 1159 (2011);331Science
 

Summary:  family of ATPases (2). The AAA ATPases (ATPases associated with diverse cellular activities), which... , 5). Dynein is one of two AAA ATPases that has six distinct AAA do- mains concatenated within... to other AAA ATPases (7­9). 1 Department of Cellular and Molecular ...

  

Source: Vale, Ron - Department of Cellular and Molecular Pharmacology, University of California at San Francisco

 

Collection: Biology and Medicine


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