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Sample search results for: a-type potassium channels

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1 Supplemental Figure 1 Spatial distribution and kinetic properties of outward current channels in somatic and
 

Summary:  and time-constants for activation and inactivation variables of proximal A-type potassium channel... dependences and time-constants for activation and inactivation variables of distal A-type potassium channel... of muscarinic potassium ...

  

Source: Jacob, Eshel Ben - School of Physics and Astronomy, Tel Aviv University

 

Collection: Physics

 
2 0 20 40 60 80 Relative Associative Recall (%)
 

Summary:  OF ALZHEIMER'S DEMENTIA: ROLE OF A-TYPE POTASSIUM CHANNELS. JL Wiebers, PH Goodman, H Markram. Division... that selective reduction of A-type K+ channels, but not of M-type or Ca2+ -AHP channels, resulted in a striking... suppression of A-type K+ ...

  

Source: Goodman, Philip H. - Departments of Internal Medicine & Biomedical Engineering, University of Nevada, Reno

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
3 Accurate Dynamical Model of Interneuronal GABAergic Channel
 

Summary:  ] and therefore were not included in our model. Our AHP channel was modeled after [7]. 2.3 A-type channel Since... of neocortical interneurons. The #12;SIC channel was modified from an A-type channel to activate after spiking... A-type ...

  

Source: Goodman, Philip H. - Departments of Internal Medicine & Biomedical Engineering, University of Nevada, Reno

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
4 Development of Potassium Conductances in Perinatal Rat Phrenic Motoneurons
 

Summary:  , muscarine-activated, and ATP-sensitive potassium channels. The delayed rectifier and A-type potassium... rectifier (IKV) and A-type potassium currents that regulated PMN action potential and repetitive firing... rectifier (IKV), transient A- ...

  

Source: Martín-Caraballo, Miguel - Department of Biology, University of Vermont

 

Collection: Biology and Medicine

 
5 202 nature neuroscience volume 3 no 3 march 2000 news and views
 

Summary:  Li and John P. Adelman Kv4 subunits form A-type potassium channels. To replicate native currents... the molecular identity of A- type potassium channels. They describe the isolation and characterization... ascribed to native ...

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
6 Accurate Dynamical Models of Interneuronal GABAergic Channel Physiologies
 

Summary:  behavio r. The ratio of an M-type channel, fast & slow calcium-dependent potassium channels and A- type... -inactivating), [8] for A-type (sub threshold inactivating), [9] for calcium-dependent potassium (SK), and proposed... [11] and ...

  

Source: Goodman, Philip H. - Departments of Internal Medicine & Biomedical Engineering, University of Nevada, Reno

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
7 103:469-478, 2010. First published Nov 18, 2009; doi:10.1152/jn.00154.2009J Neurophysiol and Riyi Shi
 

Summary:  ;Novel Potassium Channel Blocker, 4-AP-3-MeOH, Inhibits Fast Potassium Channels and Restores Axonal... November 2009 Sun W, Smith D, Fu Y, Cheng JX, Bryn S, Borgens R, Shi R. Novel potassium channel blocker, 4... of potassium ...

  

Source: Cheng, Ji-Xin - School of Biomedical Engineering & Department of Chemistry, Purdue University

 

Collection: Materials Science ; Biology and Medicine

 
8 Transistor Probes Local Potassium Conductances in the Adhesion Region of Cultured Rat Hippocampal Neurons
 

Summary:  : transistor; potassium; conductance; channel, lo- calization; A-type; K-type; adhesion Specific sorting... ; Fromherz, 1999). Because A-type and K-type potassium channels have dis- tinct effects on the shape... of 50 mV and used a prepulse of 110 mV to remove the ...

  

Source: Sandini, Giulio - Dipartimento di Informatica Sistemistica e Telematica, Università degli Studi di Genova

 

Collection: Engineering ; Computer Technologies and Information Sciences

 
9 Ion Channels, Membrane Potential Jim Huettner and Membrane Transport 10 / 14 / 03
 

Summary:  , and MacKinnon (1998) The structure of the potassium channel: molecular basis of K+ conduction... (1994) Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification... Mechanisms of Shaker Potassium Channel Inactivation. Science ...

  

Source: Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
10 Dendritic Calcium Spike Initiation and Repolarization Are Controlled by Distinct Potassium Channel Subtypes in CA1
 

Summary:  calcium spikes must overcome the repo- larizing influence of A-type potassium channels, whose density... biophysical characteristics. It has also been proposed that A-type potassium channels play a role... in suppressing calcium spike initiation (Hoffman et al., ...

  

Source: Spruston, Nelson - Department of Neurobiology and Physiology, Northwestern University

 

Collection: Biology and Medicine

 
11 Volker Kiessling Stefano Vassanelli Potassium channel gating in adhesion: from an oocytesilicon
 

Summary:  ARTICLE Volker Kiessling Æ Stefano Vassanelli Potassium channel gating in adhesion: from an oocyte... the ionic current due to the opening of voltage-dependent potassium channels has to flow along a narrow... this hypothesis, we considered a Xenopus oocyte expressing voltage-dependent ...

  

Source: Tamm, Lukas K. - Department of Molecular Physiology and Biological Physics, University of Virginia

 

Collection: Biology and Medicine

 
12 www.stke.org/cgi/content/full/sigtrans;2005/302/pe46 Page 1 Potassium channels constitute a family of proteins with diversi-
 

Summary:  www.stke.org/cgi/content/full/sigtrans;2005/302/pe46 Page 1 Potassium channels constitute a family... environment in which it resides, potassium channels can repolarize cells after a depolarization event... in potassium transport in epithelia (1, 2). Conse- quently, the activity of ...

  

Source: Selvin, Paul R. - Department of Physics, University of Illinois at Urbana-Champaign

 

Collection: Physics ; Materials Science

 
13 102 (The 102nd National Meeting of the Korean Chemical Society) : 2008 10 16~17(.) 2
 

Summary:  -2 Potassium Channel * ** * ** EB-NCRC Potassium (K+ ) channels are found in the plasma... of cell excitability, cell volume, cell growth and proliferation, and even cell death. K+ channels share... a common selectivity filter that determines the conduction characteristics of ...

  

Source: Lee, Keun Woo - Department of Biochemistry, Gyeongsang National University

 

Collection: Biotechnology ; Biology and Medicine

 
14 www.landesbioscience.com Channels 1 Channels 4:3, 1-5; May/June 2010; 2010 Landes Bioscience
 

Summary:  by CaV 3-KV 4 channel signaling complexes. Nat Neurosci 2010; 13:333­7; PMID: 20154682. A-type potassium... from transiently activated A-type potassium channels of the KV 4 family and CaV 3 T-type calcium... and modulation of somatodendritic ...

  

Source: Turner, Ray - Departments of Cell Biology & Anatomy, Physiology and Biophysics, University of Calgary

 

Collection: Biology and Medicine

 
15 Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants
 

Summary:  activities of hERG, Kv2.1 delay rectifier voltage- gated potassium channel, Kv4.2 A-type potassium channel... Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic... mutants Qiaojie Xiong, Haiyan Sun ...

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
16 ERK Integrates PKA and PKC Signaling in Superficial Dorsal Horn Neurons. I. Modulation of A-Type K Currents
 

Summary:  of the rising phase of synaptic potentials (Yoshimura and Jessell 1989b). Finally, A-type potassium channels... ). These data indicate that PMA modulates A-type potassium channels, at least in part, by reducing both... PKA and PKC act through ERK, or do these kinases ...

  

Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
17 Neuron, Vol. 5, 527-544, October, 1990, Copyright 0 1990 by Cell Press Ion Channel Expression by White Matter Clia
 

Summary:  M), a blocker of some calcium-depen- dent potassium channels (Miller et al., 1985a). Sodium currents were found... course of expression of the inwardly rectifying potassium channel, which un- dergoes a marked transition... M), a blocker of some types of calcium-dependent potassium ...

  

Source: Corey, David P. - Department of Neurobiology, Harvard University

 

Collection: Biology and Medicine

 
18 http://nro.sagepub.com The Neuroscientist
 

Summary:  . The equilibrium potential of GABA(A)-type receptors, EGABA(A), shifts toward less negative values in elevated [K... uptake through inward-rectifying potassium (Kir) channels on astrocytes (Butt and Kalsi 2006... and Steinhauser 2006). Density and inward rectification of potassium current through glial Kir ...

  

Source: Bazhenov, Maxim - Computational Neurobiology Lab., Salk Institute for Biological Studies

 

Collection: Biology and Medicine

 
19 Voltage-Gated Potassium Channels Activated During Action Potentials in Layer V Neocortical Pyramidal Neurons
 

Summary:  (ChTX, 100 nM). Activities of A-type channels (KA) also were observed during AP repolarization. KA... to be responsible for A-type K channels in the CNS (Serodio et al. 1994), whereas Shab-related K channels (Kv2... Voltage-Gated Potassium ...

  

Source: Huguenard, John R. - Department of Neurology and Neurological Sciences, Stanford University

 

Collection: Biology and Medicine

 
20 A-type potassium channel clusters revealed using a new statistical analysis of loose patch data
 

Summary:  A-type potassium channel clusters revealed using a new statistical analysis of loose patch data... were calculated for data sets describing the distribution of A-type potassium channels on neurons... oforder for lower; x, aver- age value ofx; , expected value ...

  

Source: Wang, Samuel S.-H. - Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine


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21 J Physiol 581.1 (2007) pp 175187 175 Dendritic D-type potassium currents inhibit the spike
 

Summary:  ) demonstrated that 4-AP-sensitive, fast-inactivating dendritic A-type potassium current also provides... slowly than A-type potassium current (Storm, 1990; Grissmer et al. 1994), so D-type potassium current... , multiple potassium currents serve to restrict the size ...

  

Source: Spruston, Nelson - Department of Neurobiology and Physiology, Northwestern University

 

Collection: Biology and Medicine

 
22 The pore structure and gating mechanism of K2P Paula L Piechotta1,7
 

Summary:  ) potassium channels are important regulators of cellular electrical excitability. However, the structure... : membranes & transport Keywords: channel gating; K þ channel; K2P channel; potassium channel; TREK-1... Introduction Two-pore domain ...

  

Source: Tucker, Stephen J. - Department of Physics, University of Oxford

 

Collection: Physics ; Biology and Medicine

 
23 ION CHANNELS Voltage-gated ion channels in dendrites of hippocampal
 

Summary:  ­calmodulin- dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents. J... of a transient, A-type K+ channel increased with distance from the soma. A structurally similar channel, the h-channel... ...

  

Source: Johnston, Daniel - Center for Learning and Memory & Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collection: Biology and Medicine

 
24 The open pore conformation of potassium channels
 

Summary:  to further understand a form of Kþ channel gating known as inactivation. A-typechannels... years ago, the `ball and chain' inactivation gate of A-typechannels was shown to be formed... The open pore conformation of potassium channels ...

  

Source: Akabas, Myles - Department of Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University; Chait, Brian T. - Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, Rockefeller University; Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
25 The dendrites of hippocampal pyramidal neurons possess a wide variety of voltage-gated ion channels that are
 

Summary:  potentials (EPSPs) can inactivate these A-typechannels and thus lead to an increase in the amplitude... excitability. Also, because A-type channels rapidly inactivate with depolarization, their effectiveness... potentials also allows dendritic K¤ channels (primarily the transient ...

  

Source: Johnston, Daniel - Center for Learning and Memory & Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collection: Biology and Medicine

 
26 Computational Simulations of Interactions of Scorpion Toxins with the Voltage-Gated Potassium Ion Channel
 

Summary:  on a homology model of the Kv1.3 potassium channel, the recognitions of the six scorpion toxins, viz. agitoxin2... , charybdotoxin, kaliotoxin, margatoxin, noxiustoxin, and Pandinus toxin, to the human Kv1.3 potassium channel... , Asp-386, and Gly-380 in each subunit of the Kv1.3 potassium ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
27 *Corresponding author. E-mail: dilmore@bns.pitt.edu. Neurocomputing 26}27 (1999) 107}115
 

Summary:  that included leak, voltage-dependent sodium, delayed recti"er potassium, A-type potassium, a slow non... of Hodgkin and Huxley [5]. The parameters for A-type potassium conductances were taken from Ho... primarily by the A-type potassium ...

  

Source: Ermentrout, G. Bard - Center for the Neural Basis of Cognition & Department of Mathematics, University of Pittsburgh

 

Collection: Biology and Medicine ; Mathematics

 
28 Nature Macmillan Publishers Ltd 1997 NATURE |VOL 387 |26 JUNE 1997 869
 

Summary:  reveal two distinct A- type potassium channels in Drosophila. Science 236, 1094­1097 (1987). 23. Sheng, M... understood. Surprisingly, there turns out to be a very high density of transient A-type potassium ion... that the dendrites of CA1 pyramidal neurons have a ...

  

Source: Johnston, Daniel - Center for Learning and Memory & Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collection: Biology and Medicine

 
29 BioE332A Lab 3, 2008 1 Lab 3 January 26, 2008
 

Summary:  explored spiking due to sodium channels. In this lab, we explore adapta- tion and bursting due to potassium... and calcium channels. To realize adaptation the model uses a population of slow potassium channels (M current... ). During the spike, the neuron's depolarized potential activates ...

  

Source: Boahen, Kwabena - Department of Bioengineering, Stanford University

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
30 2006/07HISTORY CAPACITY DEVELOPMENT IN PRIORITY AREAS
 

Summary:  et al. Novel subcellular distribution pattern of A-type K+ channels on neuronal surface. J Neurosci... , such as potassium channels, distributed unevenly over their surface. Many different potassium channels are involved... in the glomerular layer of the rat olfactory ...

  

Source: Rambaut, Andrew - School of Biological Sciences, University of Edinburgh

 

Collection: Biology and Medicine

 
31 Ion Channels Potassium Channels: Symmetric, Selective, and Sensitive
 

Summary:  Ion Channels Potassium Channels: Symmetric, Selective, and Sensitive Dirk Trauner* Keywords: ion... channels · membranes · neurobiology · protein structures · structure elucidation Potassium channels occur... , such as excitability, proliferation, secre- tion, and ...

  

Source: Trauner, Dirk - Department Chemie, Ludwig Maximilians Universität München

 

Collection: Chemistry

 
32 The Effects of Potassium Currents on the Synchronization of Electrically Coupled
 

Summary:  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92 4.1.1. Potassium Channel Dynamics... ;dividual dynamics of numerous ionic channels. Potassium channels are among the most important... different potassium ...

  

Source: Lewis, Tim - Department of Mathematics, University of California, Davis

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
33 Delayed Rectifier and A-Type Potassium Channels Associated with Kv 2.1 and Kv 4.3 Expression in
 

Summary:  Delayed Rectifier and A-Type Potassium Channels Associated with Kv 2.1 and Kv 4.3 Expression... 4 A-type potassium channels by an auxiliary subunit domain. Proceedings of the National Academy... of delayed rectifier and A-type K+ currents and ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
34 Dynamical Mechanisms of Odor Processing in Olfactory Bulb Mitral Cells Daniel B. Rubin and Thomas A. Cleland
 

Summary:  and Sethupathy 2006), as may A-type (inactivating) potassium currents; data from granule cells show that IA... . These oscillations rely on a persistent sodium conductance, an inac- tivating potassium conductance, and a calcium... -dependent potassium conductance and are reset via inhibitory input such as that ...

  

Source: Keinan, Alon - Department of Biological Statistics and Computational Biology, Cornell University

 

Collection: Biology and Medicine

 
35 Biochemical characterization of the native Kv2.1 potassium channel
 

Summary:  Biochemical characterization of the native Kv2.1 potassium channel Jean-Ju Chung and Min Li... , Baltimore, MD, USA Potassium (K+ ) channel pore-forming (a) subunits are by far one of the most diverse... groups of channel pro- teins responsible for controlling membrane excitability, with ...

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
36 749 J. Gen. Physiol. The Rockefeller University Press 0022-1295/2000/06/749/10 $5.00 Volume 115 June 2000 749758
 

Summary:  potassium channels with HERG and is associated with cardiac arrhythmia. Cell. 97:175­187. Armstrong, C... of tetraethylammonium ion de- rivatives with the potassium channels of giant axons. J. Gen. Phys- iol. 58:413­437. Beam... . Long QT syndrome-associated mutations in the Per-Arnt- Sim (PAS) domain of ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
37 Neuron, Vol. 29, 669680, March, 2001, Copyright 2001 by Cell Press Coupling G -Dependent Activation to
 

Summary:  Activation to Channel Opening via Pore Elements in Inwardly Rectifying Potassium Channels In the present... gating that resembles the gating mechanism seen in a bacterial potassium channel, KcsA (Perozo... ., 1999), thus suggesting evolutionary conservation of the gating structure in ...

  

Source: Reuveny, Eitan - Department of Biological Chemistry, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
38 MECHANISMS OF DISEASE Volume 336 Number 22 1575
 

Summary:  the underlying defects in the KVLQT1 and HERG potassium channels and the SCN5A sodium chan- nels may benefit... , the transmembrane potential of the cell will become ENa ( 70 mV). If a single potassium channel opens, the cell... 's transmembrane potential will become EK ( 98 mV). Because cells have an ...

  

Source: Clapham, David E. - Department of Neurobiology, Harvard University

 

Collection: Biology and Medicine

 
39 Neuron, Vol. 4, 507-524, April, 1990, Copyright 0 1990 by Cell Press Ion Channel Expression by White Matter Glia
 

Summary:  , and an inactivating A-type potassium channel, of which at least 50% is calcium-dependent. Second, acutely isolated O-2... changes occur: sodium channels, the A-type potassium channel, and the CTX- sensitive potassium ...

  

Source: Corey, David P. - Department of Neurobiology, Harvard University

 

Collection: Biology and Medicine

 
40 BioE332A Lab 3, 2007 1 Lab 3 January 28, 2007
 

Summary:  explored spiking due to sodium channels. In this lab, we explore adapta- tion and bursting due to potassium... and calcium channels. To realize adaptation the model uses a population of slow potassium channels (M current... ). During the spike, the neuron's depolarized potential activates ...

  

Source: Boahen, Kwabena - Department of Bioengineering, Stanford University

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine


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41 Protein Surface Recognition by Rational Design: Nanomolar Ligands for Potassium Channels
 

Summary:  Protein Surface Recognition by Rational Design: Nanomolar Ligands for Potassium Channels Stefan N... May 14, 2003; E-mail: trauner@cchem.berkeley.edu Potassium channels are among the core features... regulation. Recently, the three-dimensional structures of the prokaryotic potassium ...

  

Source: Trauner, Dirk - Department Chemie, Ludwig Maximilians Universität München

 

Collection: Chemistry

 
42 GLIA 1:10-30 (1988) Ion Channel Expressionby White Matter Glia
 

Summary:  -clamping, Potassium regulation, Sodium channel, Chloride channel ABSTRACT White matter is a compact structure... rectifying potassium current that is mediated by 30- and 120-pS channels. Because these channels... of large-conductance calcium-dependent ...

  

Source: Corey, David P. - Department of Neurobiology, Harvard University

 

Collection: Biology and Medicine

 
43 Toxicon . Author manuscript Voltage-gated ion channels and gating modifier toxins
 

Summary:  : William Catterall Abstract Voltage-gated sodium, calcium, and potassium channels... surface expression of other membrane signaling proteins. Voltage-gated Potassium Channels Voltage... -gated potassium channels are activated by ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
44 Neuron, Vol. 47, 833843, September 15, 2005, Copyright 2005 by Elsevier Inc. DOI 10.1016/j.neuron.2005.08.022 The Pore Helix Dipole Has a Minor Role
 

Summary:  - dues in the potassium channel signature sequence at the pore helix C terminus. We show that these chan... in potassium channel permeation. Introduction Electrical signaling is fundamental to the biological pro- cesses... molecules that alter channel function, such as drugs that act as ...

  

Source: Reuveny, Eitan - Department of Biological Chemistry, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
45 Voltage-gated Ion Channels and Gating Modifier Toxins William A. Catterall,* Sandrine Cestle,
 

Summary:  ;2 Abstract Voltage-gated sodium, calcium, and potassium channels generate electrical signals required... membrane signaling proteins. Voltage-gated Potassium Channels Voltage-gated potassium channels... membrane potential. In this way, potassium ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
46 Development of Electrical Excitability: Mechanisms and Roles
 

Summary:  - achieve the tight regulation of emerging excitability bonne focuses on regulation of potassium channels... techniques in combination with cal- molecular species of potassium channels to func- cium and/or voltage... activity have been in potassium channel gene ...

  

Source: Betz, William J. - Department of Physiology and Biophysics, University of Colorado Health Sciences Center

 

Collection: Biology and Medicine

 
47 COLLISIONAL DEPOPULATION OF A HIGH-LYING P STATE OF POTASSIUM F. GOUNAND, J. CUVELLIER, P. R. FOURNIER and J. BERLANDE
 

Summary:  L-169 COLLISIONAL DEPOPULATION OF A HIGH-LYING P STATE OF POTASSIUM F. GOUNAND, J. CUVELLIER, P. R... sections efficaces de dépopulation collisionnelle totale du niveau 10 P du Potassium, à 470 K, induite par... collision avec des atomes de Potassium ou de gaz rare : Q (K) = 6 000 ± 3 000 Å2 ; Q (He) = 18 ± 6 Å2 ; Q

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
48 Biochem. J. (2004) 378, 745752 (Printed in Great Britain) 745 BmTx3, a scorpion toxin with two putative functional faces separately
 

Summary:  + currents). So far, it is still not entirely clear which type of potassium channel is responsible for A-type... .-F. (2001) A new class of scorpion toxin binding sites related to an A-type K + channel: pharmacological... putative functional faces separately active on ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
49 BioE332A Lab 3, 2009 1 Lab 3 January 21, 2009
 

Summary:  explored spiking due to sodium channels. In this lab, we explore adapta- tion and bursting due to potassium... and calcium channels. To realize adaptation the model uses a population of slow potassium channels (M current... ). During the spike, the neuron's depolarized potential activates ...

  

Source: Boahen, Kwabena - Department of Bioengineering, Stanford University

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
50 BioE332A Lab 3, 2010 1 Lab 3 January 5, 2010
 

Summary:  explored spiking due to sodium channels. In this lab, we explore adapta- tion and bursting due to potassium... and calcium channels. To realize adaptation the model uses a population of slow potassium channels (M current... ). During the spike, the neuron's depolarized potential activates ...

  

Source: Boahen, Kwabena - Department of Bioengineering, Stanford University

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
51 Amplitude Reduction and Loss of Selectivity in the Tail That Wags the HERG Channel
 

Summary:  of potassium channel genes related to eag in Drosophila and mammals. Proc Natl Acad Sci U S A. 1994;91: 3438... and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell. 1995;81:299­307. 5. Trudeau MC... . Molecular determinants for activation and inactivation of HERG, a human inward ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
52 Dichotomy of Action-Potential Backpropagation in CA1 Pyramidal Neuron Dendrites
 

Summary:  of 50,000 mS/cm2 and an A-type potassium channel density 20% that of the soma. R E S U L T S We... as well as delayed-rectifying and A-type potassium channels. Weak action-potential backpropa- gation... of sodium and delayed rectifying potassium ...

  

Source: Pillow, Jonathan - Department of Psychology, University of Texas at Austin; Spruston, Nelson - Department of Neurobiology and Physiology, Northwestern University

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
53 Activation of Expressed KCNQ Potassium Currents and Native Neuronal M-Type Potassium Currents by the Anti-Convulsant
 

Summary:  : potassium channels; KCNQ channels; M chan- nels; sympathetic neurons; retigabine; anti-convulsant M... out in connection with Figure 8 above, retigabine (10 M) had no significant effect on the transient "A-type... , Jentsch T, Steinlein OK (1998) A potassium channel ...

  

Source: Brown, David - Department of Neuroscience, Physiology and Pharmacology, University College London

 

Collection: Biology and Medicine

 
54 Association of Aldosterone Concentration and Mineralocorticoid Receptor Genotype with Potassium
 

Summary:  Association of Aldosterone Concentration and Mineralocorticoid Receptor Genotype with Potassium... .D. Study Objective. To identify patient-specific factors associated with spironolactone-induced potassium... , and genotypes were compared between those whose potassium levels increased by more than 0.5 mEq/L (15 patients

  

Source: Dai, Yang - Department of Bioengineering, University of Illinois at Chicago

 

Collection: Engineering ; Biotechnology

 
55 Published online 13 March 2003 Active dendrites, potassium channels and synaptic
 

Summary:  of a transient, A-type potassium channel that is expressed at high density in the dendrites and correlates... . & Sweatt, J. D. 2000 The A- type potassium channel Kv4.2 is a substrate for the mitogen- activated protein... . 2002 PKA modulation ...

  

Source: Johnston, Daniel - Center for Learning and Memory & Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collection: Biology and Medicine

 
56 Cellular/Molecular A C-Terminal Domain Directs Kv3.3 Channels to Dendrites
 

Summary:  leptorhynchus express Kv3-type voltage-gated potassium channels that give rise to high-threshold currents... reveal that different functional roles for Kv3 potassium channels at the somatic and dendritic level... to the dendritic compartment. Key words: potassium ...

  

Source: Turner, Ray - Departments of Cell Biology & Anatomy, Physiology and Biophysics, University of Calgary

 

Collection: Biology and Medicine

 
57 doi:10.1152/ajpcell.00206.2005 290:165-171, 2006. First published Aug 31, 2005;Am J Physiol Cell Physiol
 

Summary:  JD. The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK. J... KI, Strassle BW, Trimmer JS, and Rhodes KJ. Modu- lation of A-type potassium channels by a family... -state inactivation transitions in human Kv4.2 ...

  

Source: Johnston, Daniel - Center for Learning and Memory & Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collection: Biology and Medicine

 
58 Annu. Rev. Physiol. 1999. 61:80934 Copyright c 1999 by Annual Reviews. All rights reserved
 

Summary:  @bme.jhu.edu KEY WORDS: alternative splicing, calcium, calcium-activated potassium channel, electrical tuning... ) potassium channels de- termine the resonant frequency of electrically tuned hair cells. Kinetic variation... to mechanoelectrical transduction (13). BK Calcium-Activated ...

  

Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
59 Molecular Cloning and Characterization of LKv1, a Novel Voltage-Gated Potassium Channel in Leech
 

Summary:  channels which are all transient A-type currents with rapid activation and inactivation kinetics (Papazian... of A-type K channel cloned from mammalian brain. Proc Natl Acad Sci USA 88: 4386­4390. Pak MD... Molecular Cloning and Characterization of LKv1, a Novel Voltage-Gated Potassium ...

  

Source: Johansen, Jorgen - Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University

 

Collection: Biology and Medicine

 
60 Ionic Currents Underlying Developmental Regulation of Repetitive Firing in Aplysia Bag Cell Neurons
 

Summary:  four potassium currents: A-type potassium current (IKA); noninactivating delayed-rectifier (IKV1... likely contributed to the higher input resistance of the juvenile neurons. A-type potassium current... , which decrease with development, we also found that a fourth ...

  

Source: Nick, Teresa - Center for Neurobehavioral Development & Department of Neuroscience, University of Minnesota

 

Collection: Biology and Medicine


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61 DueFebruary11,2011 Biology182ProblemSet#3 NAME:__________________________________________
 

Summary:  of the room. 1. At rest, the axon membrane is selectively permeable to a. potassium b. sodium c. chloride d... current pressure cGMP (intracellular second messenger) light 3. The ion channels that underlie the changes... be described as a _____________-gated ion channel. 5. The channel that underlies ...

  

Source: Devoto, Stephen H. - Biology Department, Wesleyan University

 

Collection: Environmental Sciences and Ecology

 
62 4-AMINOPYRIDINE DERIVATIVES ENHANCE IMPULSE CONDUCTION IN GUINEA-PIG SPINAL CORD FOLLOWING TRAUMATIC INJURY
 

Summary:  in myelinated fibers by blocking A-type potassium channels (Bostock et al., 1981). This has been demonstrated... , West Lafayette, IN 47907, USA Abstract--4-Aminopyridine (4-AP), a potassium channel blocker, is capable... side effects. As an initial step toward the goal of identifying ...

  

Source: Shi, Riyi - Weldon School of Biomedical Engineering, Purdue University

 

Collection: Biology and Medicine ; Engineering

 
63 Neuron, Vol. 2, 39-51, January, 1990, Copyright 0 1990 hy Cell Press Gating Mechanism of a Cloned Potassium Channel
 

Summary:  by Zagotta et al. (1989) and Zagotta and Al- drich (1989) for A-type K+ channels encoded by vari- ous... and Hille, 1987; Vandenberg and Horn, 1984; Yue et al., 1989) and the Shaker A-type K+ channel (Zagotta et... Potassium Channel Expressed in Frog Oocytes and ...

  

Source: Liman, Emily - Department of Biological Sciences, University of Southern California

 

Collection: Biology and Medicine

 
64 Long-Term Effects of Prior Heat Shock on Neuronal Potassium Currents Recorded in a Novel Insect Ganglion Slice Preparation
 

Summary:  dominated by an A-type current. Heat-shock induced alteration in the response to temperature changes... -rectifier current and instead evoke an inactivating K conductance with A-type characteristics. The inactivation... properties of this A-type cur- rent were altered at higher temperatures because at a holding potential of 70

  

Source: Robertson, Meldrum - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
65 Potassium Currents in Developing Neurons ANGELES B. RIBERAa
 

Summary:  suggested that the diverse population of neurons expressed a common potassium channel. Thus, recent efforts... have been directed towards cloning the relevant potassium channel gene. However, these molecular... . These efforts have taken advantage of the advances in molecular cloning of ...

  

Source: Betz, William J. - Department of Physiology and Biophysics, University of Colorado Health Sciences Center

 

Collection: Biology and Medicine

 
66 Specific T-type calcium channel isoforms are associated with distinct burst phenotypes
 

Summary:  .3 channels with an A-type potassium current creates a novel voltage-first spike latency relationship instead... . It has been shown that the contribution of T-type channels to LVA calcium spikes can be regulated by A-type... by coexpression of potassium ...

  

Source: Turner, Ray - Departments of Cell Biology & Anatomy, Physiology and Biophysics, University of Calgary

 

Collection: Biology and Medicine

 
67 Neuron, Vol. 16, 441453, February, 1996, Copyright 1996 by Cell Press NAB Domain Is Essential for the Subunit
 

Summary:  for the Subunit Assembly of both ­ and ­ Complexes of Shaker-like Potassium Channels Weifeng Yu,* Jia Xu,* and Min... of associating with Kv 1 inbetween Kv 1 and NShB. #12;Subunit Assembly of Potassium Channels 445 Figure 4... #12;Subunit Assembly of Potassium ...

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
68 Inward Rectifier Potassiwn Channels Cloning, Expression and Structure~FunctionStudies
 

Summary:  -transmembrane domain inward rectifier potassium channel family from rat brain, heart, and skelet.a..l muscle. When... reaction (PCR) Two-transmembrane do- main potassium channel family Inward rectifier potassium channel (Kir... structural similarities, mammalian ...

  

Source: Tucker, Stephen J. - Department of Physics, University of Oxford

 

Collection: Physics ; Biology and Medicine

 
69 EXAM NUMBER: MODULE 0230725: CELLULAR AND MOLECULAR NEUROSCIENCE
 

Summary:  that allows the expression of an inwardly rectifying potassium channel in a small number of the neuronal cells... . The potassium channel acts to eliminate action potentials and `silences' the cells in which it is expressed. You... suspect that over time, the synaptic connections between the ...

  

Source: Elliott, Chris - Department of Biology, University of York (UK)

 

Collection: Environmental Sciences and Ecology

 
70 1106 nature neuroscience volume 2 no 12 december 1999 The relay of information at most synapses in the central nervous
 

Summary:  of transient A-type potassium channels, IA, rescued the efficacy of AMPA receptors in supporting synaptically... bulb by an A-type potassium current N. E. Schoppa and G. L. Westbrook Vollum Institute, Oregon Health... . A transient A-type ...

  

Source: Betz, William J. - Department of Physiology and Biophysics, University of Colorado Health Sciences Center

 

Collection: Biology and Medicine

 
71 Technologies for Licensing Centre for Cellular and Molecular Platforms (C-CAMP)
 

Summary:  .ccamp.res.in A novel potassium channel modulator peptide Invention ID: CMP-006 Abstract: A novel 13-residue peptide Mo... that the peptide targets non-inactivating voltage dependent potassium channels. Applications: Potassium channels... or alleviation of disorders ...

  

Source: Bhalla, Upinder S. - National Centre for Biological Sciences, Tata Institute of Fundamental Research

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
72 Letter to Neuroscience EVOLUTION TUNES THE EXCITABILITY OF INDIVIDUAL NEURONS
 

Summary:  , 660 South Euclid, St Louis, MO 63110, USA Key words: potassium channels, genes, TWIK, task, C. elegans... that a class of nonconserved potassium channels highly expanded in C. elegans may play a special role... potassium channels having four transmembrane domains ...

  

Source: Nonet, Michael L. - Department of Anatomy and Neurobiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
73 Activation of Kv7 (KCNQ) voltage-gated potassium channels
 

Summary:  Activation of Kv7 (KCNQ) voltage-gated potassium channels by synthetic compounds Qiaojie Xiong1... activation) will inhibit initiation of the action potential. Potassium channels can be classified according... -activated potassium channels. Trends Neurosci. 10, ...

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
74 The voltage-gated potassium channels and their relatives
 

Summary:  The voltage-gated potassium channels and their relatives Gary Yellen Department of Neurobiology... ........................................................................................................................................................................................................................... The voltage-gated ...

  

Source: Yellen, Gary - Department of Neurobiology, Harvard University

 

Collection: Biology and Medicine

 
75 J. exp. Biol. (1977), 7*i 171-186 With 9 figures
 

Summary:  J. exp. Biol. (1977), 7*i 171-186 With 9 figures Printed in Great Britain DIEL CHANGES IN POTASSIUM... the subsidiary, broad peak in locomotor activity at dawn. 4. Diel fluctuations in whole-blood potassium... and activity changes allows some speculations about the diel movements of potassium within the blood. 5. Diel

  

Source: Foster, William A. - University Museum of Zoology, University of Cambridge

 

Collection: Environmental Sciences and Ecology

 
76 The EMBO Journal Vol.18 No.5 pp.12451256, 1999 Fast inactivation of a brain K channel composed of
 

Summary:  .1 channel can be converted to A-type upon association with Kv1.1 subunits; the conversion is only partial... the channel's expression in the plasma membrane, increases the extent of conversion to A-type. Conversely... , resulting in an increased extent of A-type conversion. Keywords: ...

  

Source: Reuveny, Eitan - Department of Biological Chemistry, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
77 This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
 

Summary:  isoprenaline. Inward rectifying potassium channels appear to be essential for the bistabil- ity. Relations... of the potassium channels is open which helps stabilize the electric potential. Too much potassium (hyperkalemia... simple model, involving only sodium ...

  

Source: Bier, Martin - Department of Physics, East Carolina University

 

Collection: Biology and Medicine ; Physics

 
78 Presynaptic Ca influx through voltage-gated Ca channels plays an important role in the release of neurotransmitters.
 

Summary:  . 1997). Thus, high concentrations of 4-AP were applied to test whether A-type-like channels are involved... ¥]pre,t, suggesting that A-typechannels were not involved. High concentrations of 4-AP reduced the amplitude... ., Lorra, C. & Pongs, O. (1997). Frequency-dependent inactivation of mammalian ...

  

Source: Saggau, Peter - Division of Neuroscience, Baylor College of Medicine

 

Collection: Biology and Medicine

 
79 Diversity of Mammalian Voltage-Gated Sodium Channels
 

Summary:  . This convention is similar to that used for potassium channels,3 and it has previously been used to designate some... in the central nervous system (CNS), Nav1.1 (Scn1A, type I), Nav1.2 (Scn2A, type II and a splice variant termed... Nav1.2A or type IIA), Nav1.3 ...

  

Source: Goldin, Alan L. - Department of Microbiology and Molecular Genetics, University of California, Irvine

 

Collection: Biology and Medicine

 
80 The Voltage Sensor in Voltage-Dependent Ion Channels FRANCISCO BEZANILLA
 

Summary:  ). Potassium channels are made of four subunits, each con- taining six transmembrane segments plus a pore loop... The Voltage Sensor in Voltage-Dependent Ion Channels FRANCISCO BEZANILLA Departments of Physiology... . Gating charge of one channel 561 III. Operation of the Sensor 562 A. Gating currents reveal ...

  

Source: Bezanilla, Francisco - Department of Biochemistry and Molecular Biology, University of Chicago

 

Collection: Biology and Medicine


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81 JOURNAL DE PHYSIQUE Colloque C7, supplement au no 11, Tome 47, Novembre 1986
 

Summary:  was determined for a constant potassium dose coadsorbed with various nickel doses. The CC coefficient... : In the first CC measurements which concerned the noise of potassium submonolayers on the W(110) plane... - quent CC investigations of potassium submonolayers and of potassium- -nickel coadsorption layers ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
82 193 J. Gen. Physiol. The Rockefeller University Press 0022-1295/2000/02/193/15 $5.00 Volume 115 February 2000 193207
 

Summary:  February 2000 193­207 Released online 31 January 2000 http://www.jgp.org Modulation of the Shaker K Channel... of California, Los Angeles, School of Medicine, Los Angeles, California 90095 abstract In Shaker K channels... ) K channel activation, we constructed S3­S4 linker deletion mutants. Using macro- patches of Xenopus

  

Source: Bezanilla, Francisco - Department of Biochemistry and Molecular Biology, University of Chicago

 

Collection: Biology and Medicine

 
83 Cellular/Molecular D2 Autoreceptors Chronically Enhance Dopamine Neuron
 

Summary:  that a change in the number of functional A-type K channels alters firing rate and susceptibility... an increase in channel noise (White et al., 2000), but upregulating A-type K channels would reduce the noise... in the macroscopic A-type cur- rent. Hence, many ...

  

Source: Horn, John P. - Department of Neurobiology, University of Pittsburgh

 

Collection: Biology and Medicine

 
84 The Contribution of Dendritic Kv3 K Channels to Burst Threshold in a Sensory Neuron
 

Summary:  that exhibit a fivefold increase in the density of A-type K channels from the soma to distal apical dendrites... an established role in feature ex- traction of sensory input. Key words: potassium channel; Kv3; dendritic spike... The Contribution of Dendritic Kv3 K Channels to Burst ...

  

Source: Turner, Ray - Departments of Cell Biology & Anatomy, Physiology and Biophysics, University of Calgary

 

Collection: Biology and Medicine

 
85 Ammonium Toxicity and Potassium Limitation David C. Hess1,2*
 

Summary:  by leakage of ammonium through potassium channels, is recapitulated under high-potassium conditions by over... , under ``limiting potassium,'' toxic amounts of ammonium might enter yeast via potassium channels as has... been observed for potassium ...

  

Source: Rabinowitz, Joshua D. - Lewis-Sigler Institute for Integrative Genomics & Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine ; Biotechnology

 
86 Ammonium Toxicity and Potassium Limitation David C. Hess1,2*
 

Summary:  by leakage of ammonium through potassium channels, is recapitulated under high-potassium conditions by over... , under ``limiting potassium,'' toxic amounts of ammonium might enter yeast via potassium channels as has... been observed for potassium ...

  

Source: Botstein, David - Lewis-Sigler Institute for Integrative Genomics & Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine

 
87 International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of
 

Summary:  Rectifying Potassium Channels YOSHIHIRO KUBO, JOHN P. ADELMAN, DAVID E. CLAPHAM, LILY Y. JAN, ANDREAS... in the human KCNJ10 potassium ion channel gene and seizure susceptibility. Epilepsy Res 58:175­183. Connors NC... , Adams ME, Froehner SC, and Kofuji P (2004) The potassium ...

  

Source: Clapham, David E. - Department of Neurobiology, Harvard University

 

Collection: Biology and Medicine

 
88 The h Current Is a Candidate Mechanism for Regulating the Sliding Modification Threshold in a BCM-Like Synaptic Learning Rule
 

Summary:  excitability shift the modification threshold to the right (also see dependence on A-type potassium channels... -gated ion channels Because changes in the A-type potassium current can also accompany various forms... curve of the A-type ...

  

Source: Narayanan, Rishikesh - Molecular Biophysics Unit, Indian Institute of Science, Bangalore

 

Collection: Biology and Medicine

 
89 104:1020-1033, 2010. First published Jun 16, 2010; doi:10.1152/jn.01129.2009J Neurophysiol Rishikesh Narayanan and Daniel Johnston
 

Summary:  (also see dependence on A-type potassium channels, below). If excitability were reduced by an increase... , that study reported a localized shift in the inactivation curve of the A-type potassium channel (from ­63... curve of the A-type ...

  

Source: Johnston, Daniel - Center for Learning and Memory & Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collection: Biology and Medicine

 
90 Annu. Rev. Neurosci. 1990. 13:441-74 Copyright1990by" AnnualReviewsInc. All rights reserved
 

Summary:  exhibit sodium currents and potassium currents (Chiu 1987). Neurotransmitter-activated channels have... that this potassium channel mediated the pro- posed spatial buffering process, although their conditions mayhave pre... rectifying potassium channels occur along ...

  

Source: Corey, David P. - Department of Neurobiology, Harvard University

 

Collection: Biology and Medicine

 
91 Downregulation of Transient K Channels in Dendrites of Hippocampal CA1 Pyramidal Neurons by Activation of
 

Summary:  , Pfaffinger PJ, Sweatt JD (1997) Kv4.2, a fast transient A-type potassium channel is a sub- strate for PKA... of Medicine, Houston, Texas 77030 We have reported recently a high density of transient A-type K channels... demonstrations of A-channel modulation. ...

  

Source: Johnston, Daniel - Center for Learning and Memory & Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collection: Biology and Medicine

 
92 Post-synaptic density perturbs insulin-induced Kv1.3 channel modulation via a clustering mechanism involving the SH3 domain
 

Summary:  -gated Shaker potassium channel and tyrosine phos- phorylation substrate of IR kinase, contains several proline... @bio.fsu.edu Abbreviations used: IR, insulin receptor; SH3, Src homology 3; Kv1.3, voltage-gated Shaker potassium channel... -gated potassium channels in ...

  

Source: Fadool, Debra Ann - Program in Neuroscience & Department of Biological Science, Florida State University

 

Collection: Biology and Medicine

 
93 KCNQ2 and KCNQ3 subunits form heteromeric potassium channels that underlie slow, subthreshold M-type
 

Summary:  KCNQ2 and KCNQ3 subunits form heteromeric potassium channels that underlie slow, subthreshold M... of single M-type KCNQ2/KCNQ3 potassium channels expressed in mammalian cells A. A. Selyanko, J. K. Hadley... /KCNQ3 channels underlying neuronal voltage- dependent M-type ...

  

Source: Brown, David - Department of Neuroscience, Physiology and Pharmacology, University College London

 

Collection: Biology and Medicine

 
94 JournalofPhysiology KCNQ2andKCNQ3subunitsformheteromericpotassium
 

Summary:  DNA plasmids, in pCR3.1 vector Rapid Report Effect of the KCNQ potassium channel opener retigabine on single... , University College London, Gower Street, London WC1E 6BT, UK KCNQ2/3 potassium channel subunits were co... KCNQ2/3 potassium channels have been reported to ...

  

Source: Brown, David - Department of Neuroscience, Physiology and Pharmacology, University College London

 

Collection: Biology and Medicine

 
95 CellBio3.doc 1 last revised 10 / 7 / 03 October 16, 2003 Voltage-Gated Channels and The Action Potential Jim Huettner
 

Summary:  of single channel recordings from voltage-gated sodium and potassium channels. Notice that the sodium... channels inactive during a continuous pulse to -40 mV, whereas the potassium channels do not. #12;CellBio3... of sodium-, calcium- and ...

  

Source: Huettner, James E. - Department of Cell Biology and Physiology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
96 The Rockefeller University Press, 0021-9525/97/03/1037/9 $2.00 The Journal of Cell Biology, Volume 136, Number 5, March 10, 1997 10371045 1037
 

Summary:  , Volume 136, Number 5, March 10, 1997 1037­1045 1037 Topology of the Shaker Potassium Channel Probed... -gated potassium channel. V oltage-gated cation channels, consisting of po- tassium, sodium, and calcium channels... derived from the amino acid sequence of the ...

  

Source: Goldin, Alan L. - Department of Microbiology and Molecular Genetics, University of California, Irvine

 

Collection: Biology and Medicine

 
97 Cellular/Molecular Robustness of Neural Coding in Drosophila Photoreceptors
 

Summary:  voltage-gated K currents: an A-type (Shaker), a slow delayed rectifier, and, in some cells, a fast delayed... rectifier (Hardie, 1991a). The A-type and slow delayed rectifier currents are clearly visible in in vitro... but leave the slowly inactivating current intact (Fig. 1b), establishing that the Shaker gene encodes the ...

  

Source: Foster, William A. - University Museum of Zoology, University of Cambridge; Juusola, Mikko - Department of Biomedical Science, University of Sheffield

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
98 Dominant-Negative Subunits Reveal Potassium Channel Families That Contribute to M-Like Potassium Currents
 

Summary:  Dominant-Negative Subunits Reveal Potassium Channel Families That Contribute to M-Like Potassium... . Neurosci., 2002, Vol. 22 Selyanko et al. · Dominant Negatives for M-Like Potassium Channels #12;GATCAG... effect on the amplitude of the transient A-type K current ...

  

Source: Brown, David - Department of Neuroscience, Physiology and Pharmacology, University College London

 

Collection: Biology and Medicine

 
99 Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers
 

Summary:  Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers Qiaojie... membrane excitability. Activation of voltage-gated potassium channels by a chemical opener is uncommon... . channel opener epilepsy genetic mutants M-currents are noninactivating, ...

  

Source: Li, Min - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
100 Nature Macmillan Publishers Ltd 1997 polyclonal antisera29
 

Summary:  ; accepted 12 May 1997. 1. Blumenthal, E. M. & Kaczmarek, L. K. The minK potassium channel exists... , 3097­3105 (1994). 2. Wang, K.-W. & Goldstein, S. A. N. Subunit composition of minK potassium channels... . Neuron 14, 1303­1309 (1995). 3. Tai, K. K., Wang, K. W. & Goldstein, S. A. N. MinK ...

  

Source: Reece, Sarah - Institute of Immunology and Infection Research & School of Biological Sciences, University of Edinburgh

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine


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