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Sample search results for: amphetamine methamphetamine mda

 

1

Methamphetamine's Effect on the Brain and Behavior

  Biology and Medicine Websites

Summary: ;3 Reward Processing · Amphetamine administration activates: ­ Medial orbitofrontal cortex. ­ Anterior and the consequence Decision-making & Methamphetamine · Amphetamine abusers show ­ Suboptimal decisions (correlated

Squire, Larry R.

2

Mechanisms of neurotransmitter release by amphetamines: A review David Sulzer a,b,*, Mark S. Sonders b,c

  Biology and Medicine Websites

Summary: Mechanisms of neurotransmitter release by amphetamines: A review David Sulzer a,b,*, Mark S 37232, USA Received 22 December 2004; accepted 18 April 2005 Abstract Amphetamine and substituted amphetamines, including methamphetamine, methylphenidate (Ritalin), methylenedioxymethampheta- mine (ecstasy

Sulzer, David

3

IMPLICATIONS OF RESEARCH FOR TREATMENT: METHAMPHETAMINE

  CiteSeer

Summary: dextroamphetamine (Dexedrine or Adderall) or they can be methamphetamine powder that has been pressed into tablets and sold as amphetamines or ecstasy. There is also a damp, sticky powder of higher purity than Speed that is known as “Base, ” “Wax, ” or “Peanut Butter. ” “Ice, ” also known as “Shard, ” “Tina, ” or

C. Maxwell, Ph.D.

4

Sociodemographic and drug use characteristics, sex behaviors, and motivations for drug use among HIV- seronegative, heterosexual, methamphetamine users in San Diego, CA

  University of California eScholarship Repository

Summary: and behavioral effects of amphetamine, methamphetamine,methamphetamine (MA) use among men who have sex with men (MSM), few studies have examined behaviors and effectsmethamphetamine (MA) use among men who have sex with men (MSM), few studies have examined behaviors and effects

Cheng, Wei-Woon Susan
2009-01-01

5

ORIGINAL PAPER Methamphetamine and Viagra Use: Relationship to Sexual Risk Behaviors

  CiteSeer

Summary: use are associated with unprotected anal intercourse among men who have sex with men (MSM). In Long Beach, California, we have reported on an association between Viagra use and the use of amphetamines during sex. The current research investigated the use of both Viagra and amphetamine in men in Long Beach, California. Data on 1,839 men recruited into HIV prevention and testing programs were collected using the Risk Behavior Assessment. A generalized logit model was constructed comparing ever having used both amphetamine and Viagra together and separately, as compared to never having used either (referent). Men who used both methamphetamine and Viagra showed a significantly higher prevalence of hepatitis B, syphilis, and HIV compared to those who used only one or neither drug. Of the 1,794 complete cases, 11.1 % (199/1794) had used both amphetamine and Viagra. Of 20 potential risk and protective factors for use of amphetamine and Viagra, 12 were significant predictors: ever used gamma-hydroxybutyrate (GHB), ever used cocaine, ever used ecstasy, being infected with HIV, race = White compared to other, ever having hepatitis B, ever using crack, ever given money to have sex, living in a hotel, ever been in drug treatment, and ever using heroin. The protective factor was being heterosexual. Viagra use was associated with insertive, and methamphetamine was associated with receptive, anal intercourse. GHB use appears to play a more important role than previously thought.

Michael R. Ware; Æ Lucy; D. G. Fisher

6

Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428

  CiteSeer

Summary: Methamphetamine and methcathinone are psychostimulant drugs with high potential for abuse. In animals, methamphetamine and related drugs are known to damage brain dopamine (DA) neurons, and this damage has recently been shown to be detectable in living nonhuman primates by means of positron emission tomography (PET) with [ 11 C]WIN-35,428, a DA transporter (DAT) ligand. The present studies determined whether living humans with a history of methamphetamine or methcathinone abuse showed evidence of lasting decrements in brain DAT density. PET studies were performed in 10 control subjects, six abstinent methamphetamine users, four abstinent methcathinone users, and three patients with Parkinson’s disease (PD). On average, subjects had abstained from amphetamine use for ?3 years. Before PET studies, all subjects underwent urine and blood toxicology screens to rule out recent

Una D. Mccann; Dean F. Wong; Fuji Yokoi; Victor Villemagne; Robert F. Dannals; George A. Ricaurte
1998-01-01

7

Methamphetamine Induces Chronic Corticostriatal Depression

  Biology and Medicine Websites

Summary: Methamphetamine Induces Chronic Corticostriatal Depression: Too Much of a Bad Thing Jeremy J. Day1 to this effect. Drug addiction is a persistent, relapsing brain disorder characterized by a progres- sive-releasing psychostimu- lant methamphetamine alters neurotrans- mission at corticostriatal synapses. Imag- ing

Sulzer, David

8

Pinjia Meng1 David D.Y. Chen2

  Chemistry Websites

Summary: to analyze trace amount ampheta- mines in human hair. Keywords: Amphetamine / Cation-selective exhaustive-derivatives such as methylenedioxy-ampheta- mine (MDA), methylenedioxy-methamphetamine (MDMA) and methylenedioxyethyl

Chen, David D.Y.

9

Methylphenidate vs. amphetamine: Comparative review

  CiteSeer

Summary: This article compares the two most common medications for Attention-Deficit/Hyperactivity Disorder (ADHD), using data from controlled studies. Medline and Psychinfo searches were done for 1984-1996 with the key words methylphenidate (MPH) and amphetamine (AMP); these were supplemented with known prior and recent literature. Of 92 animal studies found, 15 showed clear differences between the two drugs. Ten reports of controlled crossover ADHD clinical trials (three in the same sample) and a dozen other articles comparing the two drugs in humans were found. MPH is a pure re-uptake inhibitor of catecholamines, especially dopamine; AMP also releases catecholamines. Lab animals showed differential interactions with other drugs and with behavioral paradigms. Human response profiles are noncongruent. An ADHD patient who fails on one stimulant should try the other. Of 174 patients in the 6 clearest crossover studies, 48 responded better to AMP, 27 to MPH, and at least 72 to both, which is an 87+ % overall response rate if both are tried. All crossovers, except the one with comorbid Tourette's, showed a nonsignificant tendency for AMP superiority in response rate. Summed data suggest suspected differences in side effects (AMP more sleep and appetite loss and exacerbation of tics in comorbid Tourette's, MPH possibly more depression/apathy and stomachaches) and effects on comorbid disorders (AMP better for conduct/oppositional symptoms, MPH for Tourette's and possibly learning disorder (LD). Most of the

unknown authors

10

Amphetamine-Induced Displacement of [18 F] Fallypride

  Biology and Medicine Websites

Summary: Amphetamine-Induced Displacement of [18 F] Fallypride in Striatum and Extrastriatal Regions This study examined D-amphetamine (D-AMPH)-induced displacements of [18 F] fallypride in striatal; amphetamine challenge; humans #12;#12; #12; #12; #12; #12; #12; #12; #12; #12; #12; #12; #12; #12; #12; #12

Park, Sohee

11

ORIGINAL INVESTIGATION Further evidence of association between amphetamine

  Biology and Medicine Websites

Summary: ). However, it is also one of the most abused substances in the world. Individuals are known to vary in acute response to D-amphetamine, which may influence progres- sion to amphetamine abuse. Identifying of psychostimulant abuse and may be valuable in the therapeutic use of stimulants. Keywords Amphetamine

Gilad, Yoav

12

Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis

  Biology and Medicine Websites

Summary: Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis Zsolt Tallo´czy1 that contribute to increased risk of infection and exacerbate AIDS pathology. Citation: Tallo´czy Z, Martinez J

Sulzer, David

13

The Methamphetamine Situation in Australia: A Review of Routine Data

  CiteSeer

Summary: 3 EXISTING INFORMATION SOURCES.................................................................6 3.1 Extent of methamphetamine use..................................................................6 3.1.1 General population...........................................................................................................6

R. Mcketin; J. Mclaren; Rebecca Mcketin; Jennifer Mclaren

14

Amphetamine Distorts Stimulation-Dependent Dopamine Overflow: Effects on D2 Autoreceptors, Transporters, and Synaptic

  Biology and Medicine Websites

Summary: Amphetamine Distorts Stimulation-Dependent Dopamine Overflow: Effects on D2 Autoreceptors York 10032, and 4Universite´ Victor Segalen, Bordeaux 33076, France Amphetamine (AMPH) is known sensitization. Key words: dopamine; amphetamine; uptake; amperometry; cyclic voltammetry; D2 receptor

Sulzer, David

15

SYSTEMIC AND INTRA-ACCUMBENS ADMINISTRATION OF AMPHETAMINE DIFFERENTIALLY AFFECTS CORTICAL ACETYLCHOLINE RELEASE

  Biology and Medicine Websites

Summary: SYSTEMIC AND INTRA-ACCUMBENS ADMINISTRATION OF AMPHETAMINE DIFFERENTIALLY AFFECTS CORTICAL experiments tested the hypothesis that the amphetamine-induced increase in dopamine release in the nucleus amphetamine to stimulate cortical acetylcholine release. The effects of systemic or intra

Bruno, John P.

16

Incentive Sensitization by Previous Amphetamine Exposure: Increased Cue-Triggered "Wanting" for Sucrose Reward

  Biology and Medicine Websites

Summary: Incentive Sensitization by Previous Amphetamine Exposure: Increased Cue-Triggered "Wanting Arbor, Michigan 48109 We reported previously that an amphetamine microinjection into the nucleus- mental pursuit. Here we show that sensitization caused by previous amphetamine administration also causes

Berridge, Kent

17

DETECTION & MAPPING OF ABNORMAL BRAIN STRUCTURE IN METHAMPHETAMINE USERS

  Biology and Medicine Websites

Summary: surface vertex, we fitted a general linear model to assess methamphetamine effects on gray matter density-induced brain injury. Figure 1. Methamphetamine Effects on Brain Structure. ...... #12;DETECTION & MAPPING OF ABNORMAL BRAIN STRUCTURE IN METHAMPHETAMINE USERS 1 P.M. Thompson, 1 K

Thompson, Paul

18

Applying mda approach for web service platform

  CiteSeer

Summary: In this paper, we present the development of an illustrative example of e-business based on two different applications of a Model-Driven Architecture (MDA) approach. In the first application, the Platform-Independent Model (PIM) is created using the Unified Modeling Language (UML). This PIM is transformed using Atlas Transformation Language (ATL) to generate the Platform-Specific Model (PSM) based on three target platforms: Java, Web Service and Java Web Service Developer Pack (JWSDP). In the second application, the PIM is created using Enterprise Distributed Object Computing (EDOC) and transformed into another PSM based on the same target platforms. For this purpose we will use the illustrative example of a travel agency to depict some issues of the approach. Then, we will discuss mappings between meta-models. 1.

Jean Bézivin; Slimane Hammoudi; Denivaldo Lopes; Frédéric Jouault
2004-01-01

19

White-matter abnormalities in brain during early abstinence from methamphetamine abuse

  University of California eScholarship Repository

Summary: implicated in effects of methamphetamine. Results TheAdditive effects of HIV and chronic methamphetamine use oneffects are already present during the first weeks of abstinence from methamphetamine and

Tobias, Marc C.; O’Neill, Joseph; Hudkins, Matthew; Bartzokis, George; Dean, Andrew C.; London, Edythe D.
2010-01-01

20

Individual differences in schizotypal personality traits correlate with amphetamine induced dopamine release in striatal and

  Biology and Medicine Websites

Summary: Individual differences in schizotypal personality traits correlate with amphetamine induced.43 mg/kg) d-amphetamine. Dopamine release, quantified by subtracting each subject's d-amphetamine scan and involves dopamine transmission in both striatal and extra-striatal brain regions. D-amphetamine induced

Park, Sohee

21

Gene expression differences in mice divergently selected for methamphetamine sensitivity

  Biology and Medicine Websites

Summary: (bQTL) for sensitivity to the locomotor stimulant effect of methamphetamine (MA) using two mouseGene expression differences in mice divergently selected for methamphetamine sensitivity Abraham A associated with sensitivity to the stimulant effects of cocaine. These results suggest that selection

Das, Soma

22

Behavioural Brain Research, 34 (1989) 111-116 11 1 Evidence that apomorphine and ( + )-amphetamine produce

  Biology and Medicine Websites

Summary: and ( + )-amphetamine produce different types of circling in rats A.R. Cools l, W. Scheenen l D. Eilam 2 and I. Golani 2:Apomorphine; ( + )-Amphetamine; Circling; Stepping; Rat Apomorphine and (+)-amphetamine are known to produce circling in naive with a subcutaneous injection of apomorphine (1.1 mg/kg; n = 8) or ( + )-amphetamine (0.5 and 1.0 mg/kg; n = 8 and n

Golani, Ilan
1989-01-01

23

Ventral pallidal neurons code incentive motivation: amplification by mesolimbic sensitization and amphetamine

  Biology and Medicine Websites

Summary: and amphetamine Amy J. Tindell,1 Kent C. Berridge,1 Jun Zhang,1 Susana Pecin~a1 and J. Wayne Aldridge1,2 1-0607, USA Keywords: addiction, amphetamine sensitization, incentive salience, neural coding, single by an unconditioned stimulus (UCS sucrose reward). Some rats were sensitized to amphetamine after training

Berridge, Kent

24

C. Spielewoy et al. 1 Hypolocomotor Effects of Acute and Daily D-amphetamine in Mice

  Engineering Websites

Summary: C. Spielewoy et al. 1 Hypolocomotor Effects of Acute and Daily D-amphetamine in Mice Lacking-mail: giros@im3.inserm.fr Running title: d-amphetamine-induced hypolocomotion in DAT-/- mice administration of amphetamine-like psychostimulants, an effect that has been previously related to the activation


25

Intra-Accumbens Amphetamine Increases the Conditioned Incentive Salience of Sucrose Reward: Enhancement of Reward "Wanting"

  Biology and Medicine Websites

Summary: Intra-Accumbens Amphetamine Increases the Conditioned Incentive Salience of Sucrose Reward. Berridge Department of Psychology, University of Michigan, Ann Arbor, Michigan 48109 Amphetamine bilateral micro- injection of intra-accumbens vehicle or amphetamine (0.0, 2.0, 10.0, or 20.0 g/0.5 l

Berridge, Kent

26

Association between the Casein Kinase 1 Epsilon Gene Region and Subjective Response to D-Amphetamine

  Biology and Medicine Websites

Summary: Association between the Casein Kinase 1 Epsilon Gene Region and Subjective Response to D-Amphetamine, or 20 mg of oral D-amphetamine. Repeated-measures ANOVA was used to analyze interactions between of D-amphetamine (p ¼ 0.001), which corresponded to a leftward shift in the dose­response curve

Gilad, Yoav

27

Digital MDA for enumeration of total nucleic acid contamination

  Biotechnology Websites

Summary: extraction, protein purification, digital PCR (dPCR) and dMDA were factory new or cleaned with detergent in hot water, rinsed in hot water, treated with a 0.6% hypochlor- ite solution and rinsed with sterile, UV-treated water. All solutions not containing nucleotides

Quake, Stephen R.

28

LAMP-TR-*** MDA 9049-6C-1250

  Computer Technologies and Information Sciences Websites

Summary: LAMP-TR-*** CAR-TR-*** CS-TR-**** MDA 9049-6C-1250 September 2000 Hidden Markov Models for Images Daniel DeMenthon, Marc Vuilleumier and David Doermann #12;Hidden Markov Models for Images Daniel De of images using a second-order hidden Markov mesh model. We show that the Viterbi algorithm approach used

DeMenthon, Daniel

29

Towards an MDA-based development methodology for distributed applications

  Computer Technologies and Information Sciences Websites

Summary: 71 Towards an MDA-based development methodology for distributed applications Anastasius Gavras1,alme}@ewi.utwente.nl Abstract This paper proposes a development methodology for distributed applications based on the principles with the Software Process Engineering Metamodel (SPEM). The development methodology presented in this paper is being

Pires, Luís Ferreira

30

Calling a Spade a Spade in the MDA Infrastructure

  Computer Technologies and Information Sciences Websites

Summary: to present a complete characterization of metamodeling for MDA. Form versus Content Whenever human beings wish to communicate (whether in written or spoken form) they make statements in some kind of language or to an iconic symbol found on playing cards. Hence, "tool type" and "card identification mark" are ontological

Kühne, Thomas

31

INDEPENDENT RESEARCH IN NARRATIVE STUDIES (MDA 490/494)

  Biology and Medicine Websites

Summary: study. You have seen a syllabus for every course you have taken at USC, and probably thought you could a syllabus that is tailored exclusively for you. Our required form for MDA 490/494 can be found syllabus at USC. You and your supervisor both must agree to its terms, and then submit it to the Director

Rohs, Remo

32

ORIGINAL INVESTIGATION The effects of yohimbine and amphetamine on fear

  Biology and Medicine Websites

Summary: ORIGINAL INVESTIGATION The effects of yohimbine and amphetamine on fear expression and extinction Rationale Psychostimulants, such as yohimbine and am- phetamine, can enhance learning and memory. Extinction. Previous work suggests that yohimbine facilitates extinction, using freezing as a fear measure. However

Quirk, Gregory J.

33

Methamphetamine Using Mothers: Perceptions of Prepregnancy Sexual Risks, Recognizing Unintended Pregnancy, and Engaging in the Pregnancy

  University of California eScholarship Repository

Summary: history were collected. DSM-IV Criteria Form 769 MethamphetamineHistory of Foster care Psychological Comorbidities Depression Other diagnosed mental illness Substance Abuse Cigarettes Alcohol Cocaine Heroin Methamphetamine

Stemmler, Margaret Susan
2012-01-01

34

ELSEVIER Physiology & Behavior 71 (2000) 95-106 Long T methamphetamine schedules produce circadian ensuing drug

  Biology and Medicine Websites

Summary: PHYSIOLOGY & BEHAVIOR ELSEVIER Physiology & Behavior 71 (2000) 95-106 Long T methamphetamine schedule. Following 2 months of free-running activity, all animals were administered methamphetamine (MA) i. Keywords: Methamphetamine; Circadian ensuing drug activity; Long T schedules; Type O resetting

Timberlake, William D.

35

Incorporating Agile with MDA Case Study: Online Polling System

  CERN Preprints

Summary: Nowadays agile software development is used in greater extend but for small organizations only, whereas MDA is suitable for large organizations but yet not standardized. In this paper the pros and cons of Model Driven Architecture (MDA) and Extreme programming have been discussed. As both of them have some limitations and cannot be used in both large scale and small scale organizations a new architecture has been proposed. In this model it is tried to opt the advantages and important values to overcome the limitations of both the software development procedures. In support to the proposed architecture the implementation of it on Online Polling System has been discussed and all the phases of software development have been explained.

Guha, Pritha; Shukla, Shiv Shankar Prasad; Singh, Shweta; 10.5121/ijsea.2011.2408
2011-01-01

36

D-amphetamine stimulates unconditioned exploration/approach behaviors in cray sh: Towards a conserved evolutionary function of ancestral drug reward

  Environmental Sciences and Ecology Websites

Summary: D-amphetamine stimulates unconditioned exploration/approach behaviors in cray sh: Towards 2 April 2011 Available online 12 April 2011 Keywords: Amphetamine Addiction Invertebrate Reward administration. The present work demonstrates that the administration of D-amphetamine stimulates active

Huber, Robert

37

Mechanism of MDA5 Recognition of Short RNA Ligands and Crystal Structure of PepQ

  Texas A&M University - TxSpace

Summary: differentiationassociated gene 5 (MDA5). Activation of both receptors occurs as a result of binding to RNA. MDA5 only recognizes double stranded forms of RNA, whereas RIG-I is capable of recognizing both single and double stranded RNA. In vivo, MDA5 is known...

Watts, Tylan Aubrey
2013-05-16

38

Location, location: using functional magnetic resonance imaging to pinpoint brain differences

  Biology and Medicine Websites

Summary: comparison studies between healthy volunteers and cocaine-, amphetamine- or methamphetamine of the disease. Cocaine and amphetamine-like stimulants affect the central nervous system at the synaptic level transport [3]. Methamphetamine, a compound structurally similar to amphetamine, possesses an additional

Squire, Larry R.

39

Amphetamine improves cognitive function in medicated individuals with schizophrenia and in healthy volunteers

  Biology and Medicine Websites

Summary: Amphetamine improves cognitive function in medicated individuals with schizophrenia and in healthy online 8 February 2005 Abstract Background: Recent research on schizophrenia indicates that cognitive administration of d-amphetamine can improve cognitive function in individuals with schizophrenia who are well


40

Behavioural Brain Research, 36 (1990) 161-170 161 Home base behavior in amphetamine-treated tame wild rats

  Biology and Medicine Websites

Summary: in amphetamine-treated tame wild rats (Rattus norvegicus) D. Eilam and I. Golani Department of Zoology, George S) (Revised version received 29 May 1989) (Accepted 9 June 1989) Key words: Exploration; ( + )-Amphetamine with amphetamine (0.5-5 mg/kg) locomotes in an unfamiliar environment, there are one or two places which it visits

Golani, Ilan
1990-01-01

41

The Journal of Neuroscience, May 1995, 15(5): 4102-4108 Amphetamine Redistributes Dopamine from Synaptic Vesicles to

  Biology and Medicine Websites

Summary: The Journal of Neuroscience, May 1995, 15(5): 4102-4108 Amphetamine Redistributes Dopamine from 16802 Whether amphetamine acts principally at the plasma mem- brane or at synaptic vesicles is controversial. We find that &amphetamine injection into the Planorbis giant dopamine neuron causes robust

Sulzer, David

42

Preprint Collection of Charles J. Wilson Amphetamine-induced release of dopamine from the substantia nigra in vitro

  Biology and Medicine Websites

Summary: Preprint Collection of Charles J. Wilson p. 1 Amphetamine-induced release of dopamine from of chopped tissue from the substantia nigra of the rat brain with d-amphetamine resulted in a significant of amphetamine produces a marked inhibition of neuronal activity in pars compacta of the substantia nigra (1

Wilson, Charles J.

43

MDA based-approach for UML Models Complete Comparison

  CERN Preprints

Summary: If a modeling task is distributed, it will frequently be necessary to integrate models developed by different team members. Problems occur in the models integration step and particularly, in the comparison phase of the integration. This issue had been discussed in several domains and various models. However, previous approaches have not correctly handled the semantic comparison. In the current paper, we provide a MDA-based approach for models comparison which aims at comparing UML models. We develop an hybrid approach which takes into account syntactic, semantic and structural comparison aspects. For this purpose, we use the domain ontology as well as other resources such as dictionaries. We propose a decision support system which permits the user to validate (or not) correspondences extracted in the comparison phase. For implementation, we propose an extension of the generic correspondence metamodel AMW in order to transform UML models to the correspondence model.

Chaouni, Samia Benabdellah; Mouline, Salma
2011-01-01

44

ARQUITECTURAS DE SISTEMAS DE INFORMAO E A INICIATIVA MDA MARCO COSTA*

  Computer Technologies and Information Sciences Websites

Summary: ARQUITECTURAS DE SISTEMAS DE INFORMAÇÃO E A INICIATIVA MDA MARCO COSTA* e ALBERTO RODRIGUES DA Management Group MDA approach and two concrete initiatives, Codagen and XIS. RESUMO A Arquitectura de comparação e discussão entre diversas abordagens existentes para a formalização de arquitecturas de sistemas

da Silva, Alberto Rodrigues

45

MDA-based Approach for Embedded Software Generation from a UML/MOF Repository

  Computer Technologies and Information Sciences Websites

Summary: , following the MDA approach, which is oriented to the design space exploration of embedded systems, based, Languages Keywords Embedded systems design, Design space exploration, UML, MDA. 1. INTRODUCTION Approaches algorithms; b) providing information for design space exploration algorithms about the characteristics

Wagner, Flávio Rech

46

Methamphetamine and Tribal Criminal Jurisdiction on the Wind River Reservation

  University of Kansas - KU ScholarWorks

Summary: their younger generations and future existence to this drug epidemic. Adult members of Tribal Nations using methamphetamine are committing violent crimes towards other members, sometimes resulting in death, harming children mentally and physically..., and violent.35 What is particularly striking about this drug is the degree of violence it creates in the user. The crimes users commit while high or to get high are of a more extreme variety than other drug-induced crimes in general.36 The addiction...

Cisneros, Mandy
2008-06-18

47

MDA - When a major software industry trend meets our toolset, implemented since 1994

  CiteSeer

Summary: olset in a highly efficient way, based on the UML profile technology extended through advanced features such as model transformation techniques and traceability management. Certain pragmatic issues regarding how to establish an MDA approach will also be addressed. All these leading to true, fully deployable and reusable "MDA components". Benefits of the MDA approach MDA necessitates the formalization of knowledge involved in software development. This leads to a thorough understanding of the techniques, architectures and methodologies applied, and thus provides better control of the organization's know-how. In particular, it guarantees that no knowledge is lost, and that a large organization is able to apply proven practices in a regular and systematic manner. This is the key to software quality and development productivity. Figure 1 -- Model of the UML profiles used in an organization's projects A well established MDA-based organization can provide a model of the development know-

Philippe Desfray
2001-01-01

48

Persistent Reversal of Enhanced Amphetamine Intake by Transient CaMKII Inhibition

  MIT - DSpace

Summary: Amphetamine exposure transiently increases Ca2+/calmodulin-dependent protein kinase II (CaMKII) ? expression in the nucleus accumbens (NAcc) shell and this persistently increases local GluA1 S831 phosphorylation and enhances ...

Loweth, Jessica A.

49

The urinary excretion of unchanged d-amphetamine by rats at ground level and at altitude

  Texas A&M University - TxSpace

Summary: THE URINARY EXCRETION OF UNCHANGED D- AMPHETAMINE BY RATS AT GROUND LEVEL AND AT ALTITUDE A Thesis by JAMES FRANKLIN HARWELL, JR. Submitted to the Graduate College of the Texas AgrM University in partial fulfillment of the requirements... for the degree of MASTER OF SCIENCE August 1968 Major Subject: Laboratory Animal Medicine THE URINARY EXCRETION OF UNCHANGED D- AMPHETAMINE BY RATS AT GROUND LEVEL AND AT ALTITUDE A Thesis by JAMES FRANKLIN HARWELL, JR. Approved as to style and content...

Harwell, James Franklin
1968-01-01

50

Structural Alterations of Skeletal Muscle Induced by Chronic Administration of D-Amphetamine and Food Restriction

  CiteSeer

Summary: Amphetamines are frequently used as anorexigenic drugs to facilitate fasting and weight loss, although some side effects are known. The objective of the study was to study the effects of fasting induced by amphetamine administration as compared to food restriction alone on skeletal muscle. Twelve male Wistar rats were assigned to three groups: One group (AMPH) received d-amphetamine sulphate during 14 days (20 mg/Kg/day, s.c.); group FRES was the pair-fed, food restricted control receiving each day the same quantity of food consumed by the AMPH group the day before; a control group (CONT) was fed ad libitum. Food intake and body weights were controlled daily. After 14 days the animals were sacrificed and the soleus muscles were removed for light and electron microscopical evaluation and muscle fiber morphometry. Towards the end of the experimental period, food intake returned to normal in the AMPH group due to amphetamine tolerance. The AMPH and FRES animals experienced a comparable weight loss of about 15%. The muscles fibers of the AMPH and FRES group showed a slightly (n.s.) higher incidence of central nuclei than the CONT group. Their muscle fibers atrophied by about 25%. Signs of degeneration and regeneration were observed at the ultrastructural level in both experimental groups. It is concluded that the deleterious effects on skeletal muscle are rather the common result of the alimentary restriction than the particular effect of amphetamine. Key words: amphetamine, food-restriction, skeletal muscle damage, muscle atrophy, rats.

José A. Duarte; Felix Carvalho; Konstantinos Natsis; O Remião; Maria L. Bastos; José M. C. Soares

51

Prototyping an Infrastructure for MDA Submitted in partial fulfillment of the requirements for the degree Master of

  Computer Technologies and Information Sciences Websites

Summary: particular development process in software development. Octopus, an OCL expression checking tool, can be applied as MDA transformation engine to build an Octopus based MDA infrastructure. This thesis explains how Octopus works as transformation engine in MDA infrastructure and also presents two prototypes

Moeller, Ralf

52

Sepsis: Something old, something new, and a systems view Rami Namas MDa

  Engineering Websites

Summary: ,e , Ioannis P. Androulakis PhDf , Gary F. Nieman PhDg , Steve Chang MSh , Timothy R. Billiar MDa , John A Sepsis is a clinical syndrome characterized by a multisystem response to a microbial pathogenic insult

Androulakis, Ioannis (Yannis)

53

AMPHETAMINE ACTS WITHIN THE MEDIAL BASAL FOREBRAIN TO INITIATE AND MAINTAIN ALERT WAKING

  CiteSeer

Summary: Abstract—Amphetamine-like stimulants exert well-known arousal-enhancing actions. Surprisingly, little is known concerning the neuroanatomical substrates through which these drugs enhance arousal. Previous work implicates a number of basal forebrain structures in the regulation of behavioral state. The current studies examined the effects of amphetamine infusions made directly within basal forebrain sites on behavioral, electroencephalographic, and electromyographic indices of arousal in anesthetized and unanesthetized rat. In the anesthetized rat, amphetamine elicited prolonged epochs of bilateral electroencephalographic activation when infused unilaterally (3.75 mg/150 nl) into an extended region of the medial basal forebrain, demarcated anteriorally by the anterior portion of the medial septal area (which includes posterior accumbens shell) and posteriorally by the posterior aspect of the preoptic area of the hypothalamus. In the unanesthetized (undisturbed, resting) rat, amphetamine infusions into this region elicited prolonged epochs of alert waking, which at the lowest dose (3.75 mg), qualitatively resembled normal waking. Infusions placed lateral (including within the substantia innominata), anterior (including within the core subregion of the nucleus accumbens), posterior, or dorsal to these structures, as well as directly within the lateral ventricles did not alter electroencephalographic or behavioral measures. These results indicate that a region of the medial basal forebrain, extending from the anterior medial septum/accumbens shell to the posterior preoptic area, is a site within which amphetamine-like stimulants act to enhance behavioral and electroencephalographic measures of arousal. ? 1999 IBRO. Published by Elsevier Science Ltd.

C. W. Berridge; K. Wifler

54

D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

  Biology and Medicine Websites

Summary: D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine Arrestin3 PET Dopamine released by amphetamine decreases the in vivo binding of PET radioligands to 2 h after amphetamine treatment, radioligand binding remains decreased for several hours

Shen, Jun

55

HIV, Sexually Transmitted Infections and Sexual Risk among Women who Use Methamphetamine

  University of California eScholarship Repository

Summary: experiences and history, current methamphetamine use andhistory, sexual experiences and preferences, and methamphetaminemethamphetamine use during sex was independently associated with unprotected anal and vaginal sex, sex work and self-reported history

Lorvick, Jennifer J.
2011-01-01

56

ORIGINAL INVESTIGATION Are attention lapses related to d-amphetamine liking?

  Biology and Medicine Websites

Summary: ORIGINAL INVESTIGATION Are attention lapses related to d-amphetamine liking? Michael McCloskey & Abraham A. Palmer & Harriet de Wit Received: 26 May 2009 /Accepted: 30 October 2009 /Published online: 21-mail: mikemccloskey@temple.edu M. McCloskey :A. A. Palmer :H. de Wit Department of Psychiatry and Behavioral

Gilad, Yoav

57

Neuroscience Letters 384 (2005) 198202 Cocaine-and amphetamine-regulated transcript (CART) peptide

  Biology and Medicine Websites

Summary: Neuroscience Letters 384 (2005) 198­202 Cocaine- and amphetamine-regulated transcript (CART signal-related kinase (ERK) in a pituitary-derived cell line. CART 55­102 treatment resulted in markedly attenuated by pertussis toxin pre-treatment, but not by genistein, suggesting a Gi/o-dependent mechanism

Hall, Randy A

58

An Efficient Method to Estimate Labelled Sample Size for Transductive LDA(QDA/MDA)

  Computer Technologies and Information Sciences Websites

Summary: An Efficient Method to Estimate Labelled Sample Size for Transductive LDA(QDA/MDA) Based on Bayes to Estimate Labelled Sample Size 275 kernel, and by maximizing the margin based on the unlabelled data labelled sample size becomes a necessity. Moreover, a detailed analysis of labelled sample size under


59

Evolution of MDA-5/RIG-I-dependent innate immunity: Independent evolution by domain grafting

  Biology and Medicine Websites

Summary: , Institute of Molecular Medicine, Massey Cancer Center, School of Medicine, Virginia Commonwealth University, New York, NY 10024 Edited by Morris Goodman, Wayne State University, School of Medicine, Detroit, MI interferons. However, recent recognition of melanoma differentiation associated gene-5 (MDA-5) and retinoic

DeSalle, Rob

60

Towards an MDA-based development methodology1 Anastasius Gavras1

  Computer Technologies and Information Sciences Websites

Summary: Towards an MDA-based development methodology1 Anastasius Gavras1 , Mariano Belaunde2 , Luís. This paper proposes a development methodology for distributed applications based on the principles with the Software Process Engineering Metamodel (SPEM). The development methodology presented in this paper is being

Pires, Luís Ferreira

61

REVIEW Implications of Chronic Methamphetamine Use: A Literature Review

  CiteSeer

Summary: Methamphetamine (MA) abuse is increasing to epidemic proportions, both nationally and globally. Chronic MA use has been linked to significant impairments in different arenas of neuropsychological function. To better understand this issue, a computerized literature search (PubMed, 1964–2004) was used to collect research studies examining the neurobiological and neuropsychiatric consequences of chronic MA use. Availability of MA has markedly increased in the United States due to recent technological improvements in both mass production and clandestine synthesis, leading to significant public health, legal, and environmental problems. MA intoxication has been associated with significant psychiatric and medical comorbidity. Research in animal models and human subjects reveals complicated mechanisms of neurotoxicity by which chronic MA use affects catecholamine neurotransmission. This pathology may underlie the characteristic cognitive deficits that plague chronic MA users, who experience impairments in memory and learning, psychomotor speed, and information processing. These impairments have the potential to compromise, in turn, the ability of MA abusers to engage in, and benefit from, psychosocially based chemical-dependency treatment. Development of pharmacological interventions to improve these cognitive impairments in this population may significantly improve the degree to which they may be able to participate in treatment. Atypical

Andrew J. Saxon
2005-01-01

62

MDA-based ATL transformation to generate MVC 2 web models

  CERN Preprints

Summary: Development and maintenance of Web application is still a complex and error-prone process. We need integrated techniques and tool support for automated generation of Web systems and a ready prescription for easy maintenance. The MDA approach proposes an architecture taking into account the development and maintenance of large and complex software. In this paper, we apply MDA approach for generating PSM from UML design to MVC 2Web implementation. That is why we have developed two meta-models handling UML class diagrams and MVC 2 Web applications, then we have to set up transformation rules. These last are expressed in ATL language. To specify the transformation rules (especially CRUD methods) we used a UML profiles. To clearly illustrate the result generated by this transformation, we converted the XMI file generated in an EMF (Eclipse Modeling Framework) model.

Rahmouni, M'hamed
2011-01-01

63

From Made in America to Hecho en Sinaloa: A Historical Geography of North American Methamphetamine Networks

  University of Kansas - KU ScholarWorks

Summary: ). The short-­?term effects of methamphetamine can be divided based on the neurotransmitters released. The release of norepinephrine can cause elevated blood pressure and heart.... iv ACKNOWLEDGEMENTS I have many people to thank for the completion of this dissertation. First, I would like to thank the members of my committee. I...

Gilbreath, Aaron Hastings
2012-08-31

64

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5

  Biology and Medicine Websites

Summary: online 14 June 2009 Keywords: Innate immunity Nucleic acid receptor MDA5 CTD Crystal structure a b s t r to the structures of RIG-I and LGP2 CTDs. NMR titration of MDA5 CTD with dsRNA demonstrated that a posi- tively immune re- sponses [3­5]. Viral nucleic acids, including double-stranded RNA and single-stranded RNA

Strong, Roland K.

65

Neuron, Vol. 5, 797-808, December, 1990, Copyright 0 1990 by Cell Press Amphetamine and Other Psychostimulants Reduce pH

  Plasma Physics and Fusion Websites

Summary: major drugs of abuse act by increasing extraneuronal dopamine in this projec- tion, as measuredNeuron, Vol. 5, 797-808, December, 1990, Copyright 0 1990 by Cell Press Amphetamine and Other binding (Kuczenski et al., 1990; Shalaby et al., 1983). Indeed, amphetamine reduces accumulation

Sulzer, David

66

Testing Drugs Versus Testing For Drug Use: Private Risk Management in the Shadow of the Criminal Law

  University of California eScholarship Repository

Summary: some illicit drugs (for example, cocaine and amphetamines)common drugs present were marijuana (40%) and cocaine (30%).cocaine and MDMA were less likely than amphetamines and methamphetamine to be adulterated with other drugs.

MacCoun, Robert J.
2007-01-01

67

Modern Realities of the 'Jurisdictional Maze' in Indian Country: Case Studies on Methamphetamines Use and the Pressures to Ensure Homeland Security

  University of Kansas - KU ScholarWorks

Summary: , amounting to a "jurisdictional maze." Problems that arise from modern developments, such as increased use of methamphetamine (meth) and the pressures of ensuring homeland security, become exacerbated when combined with the often perplexing realities...

Kronk, Elizabeth Ann; Thompson, Heather Dawn
2007-01-01

68

AMPHETAMINE-INDUCED ENHANCEMENT OF NEOSTRIATAL IN VIVO MICRODIALYSATE DOPAMINE CONTENT IN RATS, QUINPIROLE-PRIMED AS NEONATES

  CiteSeer

Summary: Amphetamine-induced enhancement of neostriatal in vivo microdialysate dopamine content in rats, quinpirole-primed as neonates. P. NOWAK, R. BRUS, R.M. KOSTRZEWA. Pol. J. Pharmacol., 2001, 53, 319–329. Amphetamine (AMPH)-induced sensitization of central dopamine (DA) receptors, produced by repeated AMPH treatments, is associated with increased AMPH-induced DA release in the rat forebrain. However, for DA receptor sensitization produced by repeated DA receptor agonist treatments, the effects on forebrain DA release are not known. The objective of our study was to determine this. DA receptor sensitization was produced by administering the DA D agonist quinpirole (50 ?g/kg/day) to rats, from the 1st to 11th days after birth – a process known as ‘priming’. When these rats were tested at 3 months, DA receptor sensization was manifested as increased quinpirole-induced yawning. We also found that AMPH (1.0 mg/kg, ip) acutely induced a 5-fold greater increase in DA content in the neostriatal in vivo microdialysate of these quinpirole-primed rats (vs. controls), accompanied by a reduction in dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) levels in the microdialysate. Conversely, an acute injection of quinpirole · HCl (100 ?g/kg, ip) reduced the microdialysate contents of DA, DOPAC and HVA to comparable levels in quinpirole-primed and control rats. Therefore, we can conclude that long-lived DA receptor sensitization, produced by repeated DA D agonist treatments in ontogeny, is associated with enhanced AMPH-induced DA release in the neostriatum in adulthood, but is not accompanied by evident alteration in quinpirole-induced DA release.

Pol J. Pharmacol; Ryszard Brus; Richard M. Kostrzewa

69

Supplementary Information (SI): Fig. S1: Two fixed MDA-MB-231 cells with nuclei counterstained with DAPI in the MUSIC device

  Engineering Websites

Summary: Supplementary Information (SI): Fig. S1: Two fixed MDA-MB-231 cells with nuclei counterstained of the cell nuclei in the larger channel and during invasion across the subnucleus barrier are demonstrated. The width of the larger channel is 15µm. Video S1: A sample experiment showing cell invasion in the MUSIC

Erickson, David

70

*Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA Department of Anatomy and Cell Biology, Columbia University, College of Physicians and Surgeons, New York, NY, USA

  Biology and Medicine Websites

Summary: Institute, New York, NY, USA Amphetamine (AMPH) and methamphetamine (METH) have been prescribed to over 19: ADHD, attention deficit hyperactivity disorder; AMPH, amphetamine; AO, acridine orange; CV, cyclic to amphetamines (AMPHs) collapses secre- tory vesicle pH gradients, which increases cytosolic catechol- amine

Sulzer, David

71

Research Article Day and Night GSH and MDA Levels in Healthy Adults and Effects of Different Doses of Melatonin on These Parameters

  CiteSeer

Summary: Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The pineal secretory product melatonin (chemically, N-acetyl-5-methoxytryptamine) acts as an effective antioxidant and freeradical scavenger and plays an important role in several physiological functions such as sleep induction, immunomodulation, cardiovascular protection, thermoregulation, neuroprotection, tumor-suppression and oncostasis. Membrane lipid-peroxidation in terms of malondialdehyde (MDA) and intracellular glutathione (GSH) is considered to be a reliable marker of oxidative stress. The present work was undertaken to study the modulating effect of melatonin on MDA and GSH in human erythrocytes during day and night. Our observation shows the modulation of these two biomarkers by melatonin, and this may have important therapeutic implications. In vitro dose-dependent effect of melatonin also showed variation during day and night. We explain our observations on the basis of melatonin’s antioxidative function and its effect on the fluidity of plasma membrane of red blood cells. Rhythmic modulation of MDA and GSH contents emphasized the role of melatonin as an antioxidant and its function against oxidative stress. 1.


2011-01-01

72

Invest Dermatol 1954;22:121-128. Harrison W.H. et al. Incorporation of d-amphetamine into pigmented guinea pig hair.

  CiteSeer

Summary: Baumgartner W.A. et al. Detection of phencyclidine in hair J Forensic Sci 1981;26:576-581. Smith F.P. et al. Detection of phenobarbital in bloodstains, semen, seminal stains, saliva, saliva stains, perspiration stains, and hair. J Forensic Sci. 1981;26:582-586. Suzuki S. et al. Detection of trace amounts of methamphetamine in biological materials by mass fragmentometry. Koenshu-Iyo Masu Kenkyukai 1981;6:123-132. Valente D. et al. Hair as the sample in assessing morphine and cocaine addiction. Clin

Compiled Arthur Mcbay, Ph.D.; Brj Dermatol; Urine Science; Histories J Nucl Med

73

© 1997 Cancer Research Campaign Effects of iron supplementation and ET-18-OCH3 on MDA-MB 231 breast carcinomas in nude mice

  CiteSeer

Summary: Summary Lipid peroxidation products can be cytotoxic. Our objectives were (1) to use two pro-oxidants (iron and a pro-oxidative drug) to selectively increase lipid peroxidation in the implanted human breast tumours of mice consuming fish oil and (2) to kill the cancer cells without harming normal host tissues. The theoretical basis for selective cytotoxicity is that normal cells are better able to handle oxidative stress than cancer cells. Male athymic nude mice, consuming an AIN-76 diet, were injected s.c. with MDA-MB 231 human breast carcinoma cells. Three weeks later, all mice had palpable tumours, 3-10 mm in diameter, and diets were changed to modified AIN-76 diets containing 19% menhaden fish oil and 1 % corn oil with or without supplemental 0.3 % ferric citrate. After 2 weeks, half of the mice on each diet (19 % fish oil with or without supplemental ferric citrate) were injected (three times per week for 2 weeks) with the ether-lipid drug edelfosine (ET-18-OCH3). The concentration of lipid peroxidation products in tumours (as measured by thiobarbituric acid-reactive substances, TBARS) was significantly increased by both ferric citrate and ET-18-OCH3. The TBARS in livers were not increased, nor was there evidence of other harmful side-effects to the host mice. The addition of iron enhanced tumour cell death whereas ET-1 8-OCH3 suppressed tumour cell mitosis. The use of iron supplementation combined with ET-18-OCH3 resulted in the slowest growth rate, lowest mitotic index, highest level of lipid peroxidation products and increased the cytotoxic index in tumours without detectable harm to the host. That iron supplementation increased

unknown authors
1996-01-01

74

Research Report Amphetamine alters behavior and mesocorticolimbic

  Biology and Medicine Websites

Summary: T I C L E I N F O A B S T R A C T Article history: Accepted 30 September 2010 Available online 8, nucleus accumbens; PBS, phosphate buffered saline; SSC, saline sodium citrate; PB, sodium phosphate buffer

Hull, Elaine

75

An MDA approach to tame component based software development

  Physics Websites

Summary: syntactic aspects: they should also involve functional, synchronization and Quality of Service (QoS) aspects to explicitly relate the QoS contracts attached to provided interfaces with the QoS contracts ob- tained from required interfaces. We thus introduce a QoS contract model (called QoSCL for QoS Constraint Language

Paris-Sud XI, Université de

76

Medical Hypotheses Mda~ ffwdhuu (1993) 41.118-n.2

  Biology and Medicine Websites

Summary: in the Human Body and Circular-Muscle Gymnastics S. YOM-TOV and I. GOLANI Department of Zoology, George S Wise on oscillators and on coordination between oscillators, in the human body too. Prime examples are the cardiacS IN THE HUMAN BODY AND CIRCL54RXUSCLE GYMNASTICS 119 has been described as a collection of oscillators, from

Golani, Ilan
1993-01-01

77

UMIACS-2002-83 MDA9049-6C-1250

  Computer Technologies and Information Sciences Websites

Summary: entities, or visual structures such as color patches. Segmenting objects automatically is one of the most. Such a segmentation has numerous applications, including compact video coding, automatic and semi-automatic content based description, film post-production, and scene interpretation. Transmission of videos requires

DeMenthon, Daniel

78

Early life tactile stimulation changes adult rat responsiveness to amphetamine

  Environmental Sciences and Ecology Websites

Summary: to a number of behavioral and neurophysiological changes, suggesting a change in the dopamine system their mothers produces a number of behavioral and neurophysiological changes that are dependent on several extensively in studies investigating the importance of early life social relationships on a number

Sokolowski, Marla

79

Development/Plasticity/Repair Differentiating Prenatal Exposure to Methamphetamine and

  Biology and Medicine Websites

Summary: and verbal memory (Chang et al., 2004). Diffusion tensor imaging (DTI) studies of children with prenatal MA volumes differed among 61 children (ages 5­15 years), 21 with prenatal MA exposure, 18 with concomitant in adult MA abusers, may be more vulnerable to prenatal MA exposure than alcohol exposure and that more

Thompson, Paul

80

Research paper Engineering of recombinant antibody fragments to methamphetamine

  Biotechnology Websites

Summary: Biology, University of Texas, Austin, TX, United States b Department of Chemistry and Biochemistry, University of Texas, Austin, TX, United States c Department of Chemical Engineering, University of Texas, Austin, TX, United States d Department of Biomedical Engineering, University of Texas, Austin, TX, United

Georgiou, George

81

Methamphetamine self-administration in rats developmentally exposed to lead

  Texas A&M University - TxSpace

Summary: and Mushak, 2001). Over the past 15 to 20 years, severe acute cases of lead poisoning have declined due to stringent governmental regulations (Pirkle et al, 1998). However, research suggests that chronic lead exposure at a level that is considered... or chronic iron deficiency is present in a higher percentage of 6 children from low- (29%) rather than high-income (5%) families (Mahaffey, 1995). Dietary deficiencies suffered during crucial developmental years disrupt normal synaptic...

Rocha, Angelica
2009-05-15

82

4. TITLE AND SUBTITLE: 360 ° PORT MDA – A Strategy to Improve Port Security

  CiteSeer

Summary: Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instruction, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to Washington

T. P. Leary; Frank Shoup; Wayne Collins; Author(s Leary; Timothy P
2006-01-01

83

Molecular Mechanisms of Paclitaxel Resistance and Resveratrol Sensitivity in MDA-MB-231 Breast Cancer Cells

  Biology and Medicine Websites

Summary: . To better study these cells, the paclitaxel-resistant cell line was cloned using a limiting dilution method to provide more homogeneous populations of resistant cells. The 29 clones obtained exhibited a paclitaxel IC line, the least paclitaxel-resistant clone and the most paclitaxel- resistant clone were similarly

Zhou, Yaoqi

84

A MDA approach for defining WS-Policy semantic non-functional properties

  CERN Preprints

Summary: A lot of works has been especially interested to the functional aspect of Web services. Nevertheless, it is necessary to describe their non-functional properties such as the security characteristics and the quality of service. The WS-Policy standard was recommended in 2007 to describe Web services policies including the non-functional properties. However, it doesn't provide any information of their meaning necessary for automatic processes. In this paper, we propose a Model Driven Architecture approach founded on W3C standards to generate WSDL language based files including semantic policies. We use a package of WSDL and WS-Policy profiles and transformations rules to generate Web services interfaces files including policies. We extend a XML schema profile according to SAWSDL standard to define semantic non-functional properties domains. This work contributes to minimize the development cost of Web services including semantic policies. Moreover, the generated services can be automatically processed in discove...

Belouadha, Fatima-Zahra; Roudies, Ounsa
2012-01-01

85

* Supported by the Advanced Research Projects Agency under contract MDA903--87--C--0641.

  Computer Technologies and Information Sciences Websites

Summary: a hardware independent method of assessing the amount of computation involved in processing temporal data. I of acute diabetic ketoacidosis. The TCS is specifically designed to allow information to arrive out

Russ, Thomas A.

86

Applying UML and MDA to Real Systems Design Nokia Research Center, Finland

  Physics Websites

Summary: and recomposed into so called components. While this technique is well established and well known it does suffer the objectification of functions. The result of this is that systems developed using use cases suffer from poor or non

Paris-Sud XI, Université de

87

The University of Alabama in Huntsville MDA MiDAESS Partners

  Computer Technologies and Information Sciences Websites

Summary: Strategic Planning & Financial Management Support Computer Sciences Corporation HQ0147-10-D-0019 Integration Synchronization Engineering Support (Capability Group 3) ERC, Inc. HQ0147-10-D-0006 System Engineering Integration Sensor Engineering General Test Support Computer Sciences Corporation HQ0147-10-D-0008 System Engineering

Alabama in Huntsville, University of

88

Tools for MDA Software Development: Evaluation Criteria and Set of Desirable Features

  Computer Technologies and Information Sciences Websites

Summary: to rapid changes in technology. Based on the development of a software application, a Glossary Management variety of existing technology platforms that, due to the rapidly changing technology, become obsolete over time. Every time a new technology arrives, software companies have to redesign their business

Dascalu, Sergiu

89

PEGylated Liposomal Doxorubicin Targeted to 51-Expressing MDA-MB-231 Breast Cancer Cells

  Biotechnology Websites

Summary: with polyethylene glycol, PEG) for combining the benefits associated with PEGylation, as well as imparting specific-3 Polyethylene glycol (PEG) modification often referred as PEGylation has emerged as a common strategy to ensure

Kokkoli, Efie

90

Mechanical Ventilation Jairo I. Santanilla, MDa,b,*, Brian Daniel, RRTc

  Biology and Medicine Websites

Summary: ? Is a volume-targeted strategy in place? Or is a pressure-targeted strategy being used? Is it a dual of spontaneous breathing, volume-targeted ven- tilation, pressure-targeted ventilation, or some combination. In volume- targeted (also known as volume-cycled or volume assist/control) ventilation, the ventilator


91

September 17, 2010 LSUHSC named first MDA/ALS Clinic in LA

  Biology and Medicine Websites

Summary: , and basketball ­ followed by an afternoon of bowling before heading home. About 150 fourth-graders from Benjamin Schools Science Partnership Program. During the school year, LSUHSC faculty and students teach science


92

Un estudio comparativo de dos herramientas MDA: OptimalJ y ArcStyler

  Computer Technologies and Information Sciences Websites

Summary: Campus de Espinardo 30071 Murcia jmolina@um.es Resumen. El desarrollo de software dirigido por modelos es papel han juga- do en las dos últimas décadas. Aunque está claro que el desarrollo de software dirigido Driven Architec- ture) [5,6] como un nuevo paradigma de creación de software en el que los modelos guían

Ortín, María José

93

Director's Report ATIONAL ADVISORY COUNCIL

  Biology and Medicine Websites

Summary: context regulates goal- directed behavior. Mirtazapine to Reduce Methamphetamine Use: a Randomized for methamphetamine dependence exist. Methamphetamine use is associated with high morbidity and is a major cofactor

Bandettini, Peter A.

94

Neuron, Vol. 43, 261269, July 22, 2004, Copyright 2004 by Cell Press Amphetamine Modulates Human

  Biology and Medicine Websites

Summary: dextroamphetamine (AMPH, 0.25 mg/kg) mine agonist dextroamphetamine (AMPH) was histori-treatment on brain activity played a game involving anticipa- tivity disorder (ADHD), AMPH is widely prescribed totion and receipt phasic activation, AMPH treat- motivation. Even in healthy adults with no psychiatricment "equalized

Knutson, Brian

95

amphetamines and ecstasy 2011 Global ats Assessment Global Smart ProgrammeAcknowledgements

  CiteSeer

Summary: UNODC reiterates its appreciation and gratitude to Member States for the reports and information that provided the basis of this report as well as to the International Narcotics Control Board (INCB). DISCLAIMER The publication has not been formally edited. The boundaries, names and designations used in all maps do not imply official endorsement or acceptance by the United Nations. Comments on this report are welcome and can be sent to:

Sales No. E. Xi; Middle East/south-west Asia

96

Amphetamine effects on startle gating in normal women and female rats

  University of California eScholarship Repository

Summary: pill administration. Heart rate and blood pressure wereheart rate (BPM beats per minute), and both diastolic and systolic blood pressure (heart rate (F=5.39, df 1, 16, p<0.035), diastolic and systolic blood pressure (

Talledo, Jo A.; Sutherland Owens, Ashley N.; Schortinghuis, Tijmen; Swerdlow, Neal R.
2009-01-01

97

Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative

  Computer Technologies and Information Sciences Websites

Summary: Genetics, University of Chicago, Chicago, Illinois, United States of America, 2 Department of Computer Science, University of Chicago, Chicago, Illinois, United States of America, 3 Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, United States of America, 4 Department

Singh, Jaswinder Pal

98

Regulation of genes involved in dopamine transporter modulation by acute cocaine in rat striatum

  Physics Websites

Summary: by acute cocaine treatment. Interestingly, acute amphetamine treatment did not increase either in the dopamine transporter (DAT) functions following cocaine or amphetamine administration. Some studies have, conversely substrates such as amphetamine decrease these parameters [9, 12]. Amphetamine

Paris-Sud XI, Université de

99

One-Pot Methamphetamine Cooks Pose New Danger Law enforcement in Southern Illinois are reporting that they are finding full blown methamphetamine cooks taking place in Coleman

  Engineering Websites

Summary: , water, and the reactive metal (ie. Lithium) into one container from the beginning of the process such as lithium to the air then creates further explosive danger. The growing use of the one-pot method increases

US Army Corps of Engineers

100

454 This work was supported in part by the National Security Agency under Grant MDA904--84--H--0004.

  Computer Technologies and Information Sciences Websites

Summary: the ``government'' to be divided into an arbitrary number of ``tellers''. With this extension, trust in any one privacy. The second extension allows a government to reveal (and convince voters of) the winner of holding a mutually verifiable secret­ballot election. The participants are the voters, a government

Bernstein, Phil

101

Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells

  Biology and Medicine Websites

Summary: breast cancer cells Merril C. Curry a , Amelia A. Peters a , Paraic A. Kenny b , Sarah J. Roberts online xxxx Keywords: Mitochondrial calcium uniporter Breast cancer Calcium Ionomycin Cell death ABT-263+ into the mitochondrial matrix. We assessed MCU expression in clinical breast cancer samples using microarray analysis

Kenny, Paraic

102

Rising prevalence of asthma is sex-specific in a US farming Caroline A. Motika, MD,a

  Computer Technologies and Information Sciences Websites

Summary: Rising prevalence of asthma is sex-specific in a US farming population Caroline A. Motika, MD, and Philadelphia, Pa Background: Asthma prevalence is increasing worldwide in most populations, likely due populations are protected from asthma, which has been attributed to their traditional lifestyles and farming

Abney, Mark

103

Associate editor: S. Pestka Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of

  Biology and Medicine Websites

Summary: sensors in apoptosis, development and differentiation, and diabetes. © 2009 Elsevier Inc. All rights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221 Pharmacology & Therapeutics 124 (2009) 219­234 Abbreviations: Atg5, autophagy related 5 homolog (S. Cerevisiae); Atg12, autophagy related 12 homolog (S. Cerevisiae); CARD, caspase activation and recruitment

DeSalle, Rob

104

Rear-Facing Car Safety Seats: Getting the Message Marilyn J. Bull, MDa, Dennis R. Durbin, MD, MSCEb

  Geosciences Websites

Summary: manufacturers, and many research facilities, and the support of child passenger safety advocates across to 23 months old, the odds were 5.32 times higher. This information is additionally supported by data to the highest weight that is allowed for use by the manufacturer of the seat.4 Health care providers and many


105

MDA-based Configuration of Distributed Real-time and Embedded Systems Brian Dougherty, Jules White, and Douglas C. Schmidt

  Computer Technologies and Information Sciences Websites

Summary: , and Douglas C. Schmidt Institute for Software Integrated Systems Vanderbilt University, Nashville, TN 37203, smart cars, and intelligent transportation systems) are subject to stringent requirements, rigorous quality of service (QoS) demands (such as dependability and security), may require a system

Schmidt, Douglas C.

106

Exhibit 2 • neurological findings. He wa _ di_h_,.gA] Near Fatal Reaction to Ingestion of the onth,,oo,th o p,...., y pc,<

  CiteSeer

Summary: • been using various drugs, and had ta;::_: sa:I amphetamine and _ecobarh{tal orally d_a- * ou--l. DrugMDA " ing the five-day period prior to h_p_'. The: Keith C. Richards, MD, and Harold H. Borg_tedt, bid talization. He had no prior experi _ sex'- with MDA. On. the night of admi_aio _ NF: 3,$-Methylenedicrxyamphetamine (MDA) is a halluci_wgenic drug far ingested one capsule of the drug..: • Upon arrival in the emergency dep_t.': _ i which, thus far, there have been no reported serious adverse effects. 4 _ ment about one hour after the ingesti_'_e Tkr_e cases reported here document a near fatal, a severe, and a mr_ld ' % the patient was diaphoretic and tremaloua_:/. _'_ adi,erse reaction to ingestion of a single 500 mg capsule of pure MDA. His pulse rate was 140 be_ats per mmme den and his resplrator._rate was 30 ver minute>.-'.: toxi Graded doses of pure MDA were administered to a series of mice, a cat, Blood pr_sure was 150180 mm Hg. I-L_j[./_; mat and a dog. Similar effects were observed, but the dosage was. pih were widely dilated and nonrea_v.bi_-: _ ten apyrazimately ten times greater.... ". There.,were constant lateral roving _:_¢ _ovements, ,-.... occaslonaYly-rotator_f __..i_._:,,_.:,,, con.....:: '. " ": '-........ movements, coarse tremors of the lip_d_' _ ' ma

unknown authors

107

Methamphetamine Using Mothers: Perceptions of Prepregnancy Sexual Risks, Recognizing Unintended Pregnancy, and Engaging in the Pregnancy

  University of California eScholarship Repository

Summary: had histories of childhood sexual and abuse trauma whichChildhood Trauma History of Sexual Assault History of Violent Trauma History of Foster care Psychological Comorbidities Depression Other diagnosed mental illness Substance Abuse

Stemmler, Margaret Susan
2012-01-01

108

Gray-Matter Volume in Methamphetamine Dependence: Sources of Variability and Behavioral Relevance

  University of California eScholarship Repository

Summary: remediation therapy for adolescents with anorexia nervosa.therapies improve treatment of schizophrenia (Bell et al, 2001), attention-deficit hyperactivity disorder (O'Connell et al, 2006), and anorexia

Morales, Angelica Marie
2014-01-01

109

Patterns of Methamphetamine Use During Pregnancy: Results from the Infant Development, Environment, and Lifestyle (IDEAL) Study

  University of California eScholarship Repository

Summary: cantly more prenatal care Matern Child Health J (2010) 14:users sought prenatal care Matern Child Health J (2010) 14:Health J (2010) 14:519–527 topics: (1) information about the course of her pregnancy and number of prenatal


2010-01-01

110

HIV, Sexually Transmitted Infections and Sexual Risk among Women who Use Methamphetamine

  University of California eScholarship Repository

Summary: of intimate partner violence include cocaine or crack use,Violence among individuals in substance abuse treatment: the role of alcohol and cocaineviolence and the substance use factors examined, including heavy alcohol and crack cocaine

Lorvick, Jennifer J.
2011-01-01

111

Suburban Poverty: Barriers to Services and Injury Prevention among Marginalized Women Who Use Methamphetamine

  University of California eScholarship Repository

Summary: to access emergency resources, such as shelter in theincluded emergency food services and homeless shelters. Oneemergency financial assistance, and inpatient substance abuse treatment. To our surprise, even domestic violence shelters

Boeri, Miriam W.; Tyndall, Benjamin D; Woodall, Denise R
2011-01-01

112

Effects of Methamphetamine on Lung Inflammation Sarah Hamblock1, Ray Hamilton, Mary Buford, Andrij Holian

  Mathematics Websites

Summary: silica particles, a positive control. A MTS assay was used to determine the toxicity of the chemicals on the cells, and IL-1 levels were measured using an ELISA kit. MA and TPP were not found to be signi cantly

Vonessen, Nikolaus

113

HIV, Sexually Transmitted Infections and Sexual Risk among Women who Use Methamphetamine

  University of California eScholarship Repository

Summary: computer-based personal interviewing system (Blaise®, Westat). Biological testing included HIV, syphilis, herpes simplex viruscomputer-based personal interviewing system (Blaise®,Westat). Biological testing included HIV, syphilis, herpes simplex virus

Lorvick, Jennifer J.
2011-01-01

114

Methamphetamine Using Mothers: Perceptions of Prepregnancy Sexual Risks, Recognizing Unintended Pregnancy, and Engaging in the Pregnancy

  University of California eScholarship Repository

Summary: Adolescent Drug Initiation: Theories to Ponder” Substance Abuseadolescents in southern california: Participant characteristics and treatment response. Journal of Substance Abuse,adolescents in Southern California: Participant characteristics and treatment response. Journal of Substance Abuse,

Stemmler, Margaret Susan
2012-01-01

115

Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of

  Biology and Medicine Websites

Summary: oxidize to produce quinones and additional reactive oxygen species, may account for this selective of vesicular sequestration. Electron microscopy and fluorescent labeling confirmed that METH promoted cellular pathway that is activated when DA cannot be effectively sequestered in synaptic vesicles, thereby

Sulzer, David

116

Methamphetamine Using Mothers: Perceptions of Prepregnancy Sexual Risks, Recognizing Unintended Pregnancy, and Engaging in the Pregnancy

  University of California eScholarship Repository

Summary: Passive recruitment for this study was conducted at five women-only residential substance abuse treatmentpassive recruitment was conducted. Flyers were posted for nine months at five women-only residential drug treatment

Stemmler, Margaret Susan
2012-01-01

117

A Spatial Analysis of Methamphetamine Lab Seizures for Jefferson County, Mo

  University of Kansas - KU ScholarWorks

Summary: age Percent poor Mothers Distance to Nearest PD Unemployment Rate Median HH income OLS Results Adjusted R 2 = .225 Akaike Info. Crit.: ?7.0014 Variables Coefficients Probability Population Density -0.11 0.04 Unemployment 023 0 0110....23 . Distance to PD 0.26 0.029 Local Moran’s I Of OLS Residuals Lag Model Coeffi ie t P obabilitc n r y Lag Variable 0.389 0.0009 Pop Density -0.08 0.1108 Unemployment 0.204 0.014 Distance to PD 0 002 0 105. . ...

Gilbreath, Aaron Hastings
2010-11-18

118

Repeated Exposure to Methamphetamine Causes Long-Lasting Presynaptic Corticostriatal Depression

  Biology and Medicine Websites

Summary: -term maintenance. INTRODUCTION Substance abuse is a chronic relapsing disorder in which drug reinstatement, even *Correspondence: bamford@u.washington.edu DOI 10.1016/j.neuron.2008.01.033 SUMMARY Addiction-associated behaviors. These mechanisms might provide a synaptic basis that underlies addiction and habit learning and their long

Sulzer, David

119

Methamphetamine Using Mothers: Perceptions of Prepregnancy Sexual Risks, Recognizing Unintended Pregnancy, and Engaging in the Pregnancy

  University of California eScholarship Repository

Summary: addiction, “abuse” refers to maladaptive drug use in which substanceaddiction severity among female meth users or diversity of experience in substance abusesubstance abuse history were obtained from the participants. The standardized DSM-IV Form 769 Severity of Meth Addiction

Stemmler, Margaret Susan
2012-01-01

120

Modulators of maladaptive decision-making in methamphetamine dependence: A multimodal neuroimaging approach

  University of California eScholarship Repository

Summary: participants were at rest. Resting-state fMRI was used tofMRI was used to measure temporal correlations between intrinsic brain activity in the mesocorticolimbic and corticostriatal networks at rest.fMRI). Oxygenated hemoglobin is diamagnetic and has the same magnetic properties as the rest

Kohno, Milky
2013-01-01

121

Gray-Matter Volume in Methamphetamine Dependence: Sources of Variability and Behavioral Relevance

  University of California eScholarship Repository

Summary: modulate brain activations in schizophrenia? An fMRI study.JA (2006). Brain volume in first- episode schizophrenia:brain injury or stroke, but an emerging literature suggests that these therapies improve treatment of schizophrenia (

Morales, Angelica Marie
2014-01-01

122

A sensitizing regimen of methamphetamine causes impairments in a novelty preference task of object recognition

  University of California eScholarship Repository

Summary: 0.036]. Animals in both groups showed significant memory foranimal spent investigating the novel object was the index of recognition memory.animal. The HC and pRh were chosen because of their known involvement in tasks of learning and memory,

Belcher, Annabelle M; O'Dell, Steven J; Marshall, John F
2006-01-01

123

Brain Hyperthermia During Physiological and Pathological Conditions: Causes, Mechanisms, and Functional Implications

  CiteSeer

Summary: Abstract: Although brain metabolism consumes high amounts of energy and is accompanied by intense heat production, brain temperature is usually considered a stable, tightly regulated homeostatic parameter. Current animal research, however, has shown that different forms of functional neural activation are accompanied by relatively large brain hyperthermia (2-3°C), which has an intra-brain origin; cerebral circulation plays a crucial role in dissipating this potentially dangerous metabolic heat from brain tissue. Brain hyperthermia, therefore, reflects enhanced brain metabolism and is a normal physiological phenomenon that can be enhanced by interaction with common elements of an organism’s environment. There are, however, instances when brain hyperthermia becomes pathological. Both exposure to extreme environmental heat and intense physical activity in a hot, humid environment restrict heat dissipation from the brain and may push brain temperatures to the limits of physiological functions, resulting in acute life-threatening complications and destructive effects on neural cells and functions of the brain as a whole. Brain hyperthermia may also result from metabolic activation induced by various addictive drugs, such as heroin, cocaine, and meth-amphetamine (METH). In contrast to heroin and cocaine, whose stimulatory effects on brain metabolism invert with increases in dose, METH increases brain metabolism dosedependently and diminishes heat dissipation because of peripheral vasoconstriction. The thermogenic effects of this drug, moreover, are enhanced during physiological activation, resulting in pathological brain hyperthermia. Since brain hyperthermia exacerbates drug-induced toxicity and is destructive to neural cells, uncontrollable use of amphetamine-like drugs under conditions restricting heat dissipation from the brain may result both in acute lifethreatening complications and clinically latent but dangerous morphological and functional brain destruction.

Eugene A. Kiyatkin

124

Affective Analgesia Following Muscarinic Activation of the Ventral Tegmental Area in Rats

  Biology and Medicine Websites

Summary: from observations that strong an- algesics (eg, morphine, amphetamine) have high abuse potential of morphine and amphetamine.2 Mesoaccumbal dopaminergic neurons in the VTA are activated via cholinergic

Borszcz, George S.

125

BEHAVIORAL AND BRAIN SCIENCES (1992) 15, 249-808 Printed in the United States of America

  Biology and Medicine Websites

Summary: ofthe nonselective dopaminergic drugs apomorphine and amphetamine and partly also the selective dopamine should prove useful to ethologists and neurobiologists. Keywords: amphetamine; apomorphine; drug

Golani, Ilan
1992-01-01

126

Profilin1 regulates PI(3,4)P-2 and lamellipodin accumulation at the leading edge thus influencing motility of MDA-MB-231 cells

  MIT - DSpace

Summary: Profilin1, a ubiquitously expressed actin-binding protein, plays a critical role in cell migration through actin cytoskeletal regulation. Given the traditional view of profilin1 as a promigratory molecule, it is difficult ...

Bae, Yong Ho

127

Progress Report on the LTS/UMIACS Contract RFP:MDA904-02-R-0151 SOW: R4-02-0001.1

  Environmental Sciences and Ecology Websites

Summary: , 2004 Joseph JaJa University of Maryland Institute for Advanced Computer Studies (UMIACS) and Department of Electrical and Computer Engineering This report represents work completed during the time period Oct 1, 2003 and the pages where related progress is described. Project Page 1. Active Network Management 2 1.1 Overlay

Gruner, Daniel S.

128

Progress Report on the LTS/UMIACS Contract RFP:MDA904-02-R-0151 SOW: R4-02-0001.1

  Environmental Sciences and Ecology Websites

Summary: (with respect to number of outgoing and incoming packets). The distributed architecture of our detection.e., outgoing traffic goes through one router and incoming traffic for that same connection comes via

Gruner, Daniel S.

129

Development of Performance Properties of Ternary Mixtures and Concrete Pavement Mixture Design and Analysis (MDA): Effect of Paste Quality on Fresh and Hardened Properties of Ternary Mixtures

  CiteSeer

Summary: The mission of the National Concrete Pavement Technology Center is to unite key transportation stakeholders around the central goal of advancing concrete pavement technology through research, tech transfer, and technology implementation. Disclaimer Notice The contents of this report reflect the views of the authors, who are responsible for the facts and the accuracy of the information presented herein. The opinions, findings and conclusions expressed in this publication are those of the authors and not necessarily those of the sponsors. The sponsors assume no liability for the contents or use of the information contained in this document. This report does not constitute a standard, specification, or regulation. The sponsors do not endorse products or manufacturers. Trademarks or manufacturers ’ names appear in this report only because they are considered essential to the objective of the document. Iowa State University Non-Discrimination Statement Iowa State University does not discriminate on the basis of race, color, age, religion, national origin, sexual orientation, gender identity, genetic information, sex, marital status, disability, or status as a U.S. veteran. Inquiries can be directed to the Director of Equal Opportunity and

unknown authors
2012-01-01

130

Progress Report on the LTS/UMIACS Contract RFP:MDA904-02-R-0151 SOW: R4-02-0001.1

  Environmental Sciences and Ecology Websites

Summary: the algorithms at the monitors to collect enhanced statistics. We use these statistics to score the malicious quality of the suspected flows and use the score to detect attacks. The scoring of flows enables unified better by decreasing the detection times for the attacks. We applied the new scoring algorithms (with

Gruner, Daniel S.

131

Anti-androgenic activities of environmental pesticides in the MDA-kb2 reporter cell line S. At-Assa *,1

  Physics Websites

Summary: , reproduction, as well as neuro-endocrine system functioning. A large diversity of environmentally occurring suspected to act as endocrine disruptive compounds (EDCs) through several mechanisms of action, however data cell line. The responsiveness of the system was checked by using a panel of reference ligands

Paris-Sud XI, Université de

132

Affective Correlates of Stimulant Use and Adherence to Anti-retroviral Therapy Among HIV-positive Methamphetamine Users

  University of California eScholarship Repository

Summary: positive emotions in positive psychology: The broaden-and-positive and negative affect: The PANAS scales. Journal of Personality and Social Psychology,positive and negative affect to adolescent substance use: Test of a bidimensional model in a longitudinal study. Psychology

Carrico, Adam W.; Johnson, Mallory O.; Colfax, Grant N.; Moskowitz, Judith Tedlie
2010-01-01

133

The Journal of Neuroscience, April 1994, 74(4): 2260-2271 Methamphetamine Neurotoxicity Involves Vacuolation of Endocytic

  Biology and Medicine Websites

Summary: selective degeneration of dopamine (DA) neuron terminals without cell body loss. While excitatory amino is excitotoxicity selective for DA fibers; rather, EAAs may mod- ulate MA-induced DA turnover, suggesting that DA midbrain DA neu- ron cultures maintained under continuous EAA blockade. As in viva, MA caused neurite

Sulzer, David

134

The Emerging Problem of Methamphetamine: A Threat Signaling the Need to Reform Criminal Jurisdiction in Indian Country

  University of Kansas - KU ScholarWorks

Summary: that federal laws are necessary to protect public safety, numerous statistical surveys suggest that the federal Indian country criminal justice regime has not achieved any such purpose.” Rather, the failure of the federal criminal justice system in Indian...

Kronk, Elizabeth Ann
2006-01-01

135

Neuron, Vol. 19, 12711283, December, 1997, Copyright 1997 by Cell Press Vesicular Transport Regulates Monoamine Storage

  Biology and Medicine Websites

Summary: Regulates Monoamine Storage and Release but Is Not Essential for Amphetamine Action activities use the Na to the original hypothesis that monoamine transmit- brain cultures from the mutant animals, amphetamine ters have. In The action of amphetamines further indicates the po- vivo, amphetamine increases movement, promotes tential

Sulzer, David

136

Transient Overexpression of {alpha}-Ca2+/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell Enhances Behavioral Responding to Amphetamine

  MIT - DSpace

Summary: Ca[superscript 2+]/calmodulin-dependent protein kinase II (CaMKII) is known to contribute to the expression of psychostimulant sensitization by regulating dopamine (DA) overflow from DA neuron terminals in the nucleus ...

Loweth, Jessica A.

137

Research Articles Altered Profiles of Spontaneous Novelty Seeking, Impulsive Behavior, and Response to D-Amphetamine in Rats Perinatally Exposed to Bisphenol A

  CiteSeer

Summary: Bisphenol A (BPA) is an environmental estrogen with potentially averse effects on public health. We studied the long-term effects of perinatal exposure to BPA on later behavior in adult rats of both sexes. BPA or vehicle was administered orally to mother rats from mating to pups ’ weaning, at a concentration (0.040 mg/kg) within the range of human exposure. The offspring of both sexes were tested at adolescence (postnatal days 35–45) for novelty preference (experiment 1). After a 3-day familiarization to one side of a two-chamber apparatus, on day 4 rats were allowed to freely explore the whole apparatus. BPA-exposed females spent significantly less time than did controls in exploration of the novel side (i.e., increased neophobia), whereas no effect was found in the male group. At adulthood, the same animals were food deprived and tested for profiles of impulsive behavior (experiment 2), in operant chambers provided with two nose-poking holes (delivering either five or one food pellet). After the establishment of a baseline preference for the large reinforcer, a delay was introduced before the delivery of the five food pellets, which was

Walter Adriani; Daniele Della Seta; Francesco Dessì-fulgheri; Francesca Farabollini; Giovanni Laviola

138

ORIGINAL INVESTIGATION Single-trials analyses demonstrate that increases in clock

  Biology and Medicine Websites

Summary: . Materials and methods The present report evaluates the effects of five doses of methamphetamine (MAP) (0 to the methamphetamine-induced horizontal shifts in peak-interval timing functions Matthew S. Matell & Melissa Bateson of the present experiment is to evaluate whether methamphetamine (MAP)-induced alterations in behavior

Matell, Matthew S.

139

Behavioral/Systems/Cognitive Striatal Dopamine D2/D3 Receptor Availability Is Reduced in

  Biology and Medicine Websites

Summary: in Methamphetamine Dependence and Is Linked to Impulsivity Buyean Lee,1* Edythe D. London,1,2,4* Russell A. Poldrack methamphetamine addiction has been associated with both impulsivity and striatal dopamine D2 /D3 receptor deficits, human studies have not directly linked the latter two entities. We therefore compared methamphetamine

Poldrack, Russ

140

Neurobiology of Disease Structural Abnormalities in the Brains of Human Subjects

  Biology and Medicine Websites

Summary: Methamphetamine Paul M. Thompson,1 Kiralee M. Hayashi,1 Sara L. Simon,2 Jennifer A. Geaga,1 Michael S. Hong,1, the profile of structural deficits in the human brain associated with chronic methamphetamine (MA) abuse-based maps suggest that chronic methamphetamine abuse causes a selective pattern of cerebral deterioration

Thompson, Paul

141

Available online at www.sciencedirect.com Drug and Alcohol Dependence 94 (2008) 258262

  Biology and Medicine Websites

Summary: communication Residual effects of intranasal methamphetamine on sleep, mood, and performance Audrey Y. Pereza residual effects on early next-day performance. Future studies should assess methamphetamine). These deleterious effects appear to be exacerbated following abrupt discontinu- ation of methamphetamine use (Peck

Silver, Rae

142

This article was downloaded by: [Tel Aviv University] On: 11 May 2013, At: 02:23

  Biology and Medicine Websites

Summary: -ses- sion with 5 m a g (+)-amphetamine [AMPH]), to very low (sec- ond half-session with 5 mgkg AMPH),or can for the modeling of motor coordination Key words:amphetamine, apomorphine, locomotion, quinpirole, stereotypies

Golani, Ilan

143

Texture of locomotor path: a replicable characterization of a complex behavioral phenotype

  Biology and Medicine Websites

Summary: in other scales, and self-similarity across scales was not displayed by all genotypes. Amphetamine for behavioral phenotyping and the study of drug effects in the mouse. Keywords: Amphetamine, cocaine, curvature

Golani, Ilan

144

doi:10.1136/jme.2005.013599 2006;32;110-113J. Med. Ethics

  Biology and Medicine Websites

Summary: that amphetamines promote neural plasticity and improve recovery in aphasic patients, I advise him to take a small dose of dextro-amphetamine half an hour before each of his classes. When he is ready to fly to Saudi

Chatterjee, Anjan

145

NeuroscienceResearch62 (2008)206-209 .,',rti i:,

  Biology and Medicine Websites

Summary: , and intrastriatal 6-OHDA 3 days after treatment onset, were tested for d-amphetamine-induced rotational behavior intraperitonealinjection of d-amphetamine(5 mgikg) 3 weeks after animals receivedthe 6- OHDA treatment (day 25

Wurtman, Richard
2008-01-01

146

Glutamate Receptors in Nucleus Accumbens Mediate Regionally Selective

  Biology and Medicine Websites

Summary: . Amphetamine (2.0 mg/kg, i.p), was systemically administered as a positive control in a fourth session, since-specific manner. Systemic amphetamine administra- tion significantly increased (100­200%) ACh in the PPC

Bruno, John P.

147

NEUROSYSTEMS Astrocyte-derived kynurenic acid modulates basal and

  Biology and Medicine Websites

Summary: Keywords: amphetamine, glia, microdialysis, prefrontal cortex, schizophrenia Abstract We tested release caused by d-amphetamine (2.0 mg / kg). This effect was duplicated by the systemic administration

Bruno, John P.

148

NEUROPSYCHOPHARMACOLOGY 2002VOL. 26, NO. 6 2002 American College of Neuropsychopharmacology

  Biology and Medicine Websites

Summary: 10010 PII S0893-133X(01)00402-X Memory Processes Governing Amphetamine-induced Psychomotor Sensitization-induced unilateral dopamine depletion received repeated injections of d-amphetamine (AMPH) or saline in group

Schallert, Tim

149

Presynaptic Regulation of Dopamine Transmission in Schizophrenia Gholson J. Lyon2,8

  Biology and Medicine Websites

Summary: of widespread psychosis in populations in which amphetamines were widely abused, such as post­World War II Japan and Sweden in the 1940s and 1950s.16,17 Amphetamines release massive amounts of DA from presynaptic terminals

Sulzer, David

150

Neurosclence&BtobehavtoralRevtews.Vol 15, pp 455-460 PergamonPressplc. 1991 Pnntedm the U S A 0149-7634/91$3 00 + 00 The Description of Rat Drug-Induced Behavior

  Biology and Medicine Websites

Summary: performed by the whole ammal one at a tune By analysmg this behavior under ( + )-amphetamine (5 mg/kg), we of locomotor patlerns observed under amphetamine can be reduced to as few as 3 descriptive component

Golani, Ilan

151

118 Current Medical Imaging Reviews, 2011, 7, 118-124 1573-4056/11 $58.00+.00 2011 Bentham Science Publishers Ltd.

  Biology and Medicine Websites

Summary: - nipulation of the dopamine system (e.g., amphetamine, cocaine, methylphenidate). More recently, there has provokes an increase in endogenous NT (e.g., a surge in dopamine after amphetamine administration

Morris, Evan D,

152

The Open Neuroendocrinology Journal, 2010, 3, 21-27 21 1876-5289/10 2010 Bentham Open

  Biology and Medicine Websites

Summary: : Neurons that express pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART that express pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART). When

Toledo, University of

153

Disruption of Mesolimbic Regulation of Prefrontal Cholinergic Transmission in an Animal Model of Schizophrenia and

  Biology and Medicine Websites

Summary: . Amphetamine-evoked ACh release was assessed in nVHLX animals to exclude potential limitations in release capacity. Amphetamine produced greater increases in ACh release than in shams, indicating that nVHLX does

Bruno, John P.

154

MARCH 2002 NOTICES OF THE AMS 333 Conversationsabout

  Mathematics Websites

Summary: at conferences taking amphetamines to keep themselves in high gear. Auburn--who has a great deadpan sense play--offered Erdos as an example of a math- ematician thought to have used amphetamines, but agreed

Russo, Bernard

155

Huddling and Independent Feeding of Neonatal Rats Can be

  Biology and Medicine Websites

Summary: pharmacological agent (e.g., amphetamine; Pedersen et al., 1982), and certain natural odors (e.g., maternal saliva) found that pups which are stimulated mechanically (by stroking) or pharmaco- logically (by amphetamine

Sullivan, Regina M.

156

RESEARCH LETTERS Phentermine and other

  Biology and Medicine Websites

Summary: the norepinephrine released from sympathetic neurons. In rats, phentermine, like d-amphetamine, releases dopamine: Amphetamines and Related Compounds (E Costa, S Garattini, cds) Raven Press, NY, 1970, pp 6~73. 38 5 Morita T

Wurtman, Richard

157

Risky Subjectivity : : The Effects of Cultural Discourses of Addiction on Methamphetamine Using HIV+ Men Who Have Sex with Men in San Diego

  University of California eScholarship Repository

Summary: article wrote that the situation “raises the possibility that a hard- to-treat variant of the virusarticles mentioned above) featured not only an interview with the (still living) man, the “New York Patient,” whose drug-resistant virus

Gideonse, Theodore Karwoski

158

Am J Psychiatry 163:9, September 2006 1639ajp.psychiatryonline.org Brief Report

  Biology and Medicine Websites

Summary: in Amphetamine-Induced Displacement of [18F]Fallypride in Striatal and Extrastriatal Regions: A PET Study- sion tomography (PET) with [18F]fallypride before and after an oral dose of d-amphetamine. Percent increases striatal dopamine synthesis, baseline dopamine release, d-amphetamine-induced dopamine release

Park, Sohee

159

Behavioural Brain Research 114 (2000) 2330 Research report

  Biology and Medicine Websites

Summary: no effect relative to a within-subject injection of saline vehicle but d-amphetamine (0.1 mg the relative importance of the D1 and D2 subfamilies of receptors in the amphetamine effect, separate groups of animals received amphetamine co-injected with either SCH23390 (0.01 and 0.005 mg/kg) or eticlopride (0

Timberlake, William D.
2000-01-01

160

Disruption of EphA/ephrin-A signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral

  Biology and Medicine Websites

Summary: and dissociates behavioral responses to amphetamine and cocaine Beth-Anne Sieber,a,1 Alexander Kuzmin,b Josep M transmission revealed an unexpected dissociation of the behavioral responses to amphetamine and cocaine. In particular, transgenic mice were relatively insensitive to amphetamine while retaining normal respon

Ibáñez, Carlos

161

Catechol-O-methyltransferase val158 met genotype modulates

  Biology and Medicine Websites

Summary: -free state and in response to amphetamine Ajna Hamidovica , Andrea Dlugosa , Abraham A. Palmera,b and Harriet of d-amphetamine. Methods Healthy Caucasian male and female participants (n = 161) participated in a double-blind, crossover design study where they received placebo or d-amphetamine (10 and 20 mg

Gilad, Yoav

162

97:3166-3180, 2007. First published Mar 14, 2007; doi:10.1152/jn.01168.2006J Neurophysiol Michelle M. Rank, Xiaole Li, David J. Bennett and Monica A. Gorassini

  Biology and Medicine Websites

Summary: . Bergquist and M. A. Gorassini From Paired Motor-Unit Activity Amphetamine Increases Persistent Inward measured after increasing presynaptic release of NE by administration of amphetamine. An increase in long doses (0.1­0.2 mg/kg) of amphetamine. These findings were repeated in a reduced S2 in vitro preparation

Gorassini, Monica

163

Brain Research 894 (2001) 7487 www.elsevier.com/locate/bres

  Biology and Medicine Websites

Summary: Brain Research 894 (2001) 74­87 www.elsevier.com/locate/bres Research report Amphetamine administration of amphetamine results in increases in the release of acetylcholine in the cortex. Basal forebrain for amphetamine-induced increase in cortical acetylcholine by examining whether intra-basalis perfusion

Bruno, John P.
2001-01-01

164

C. Betancur et al. 1 Neurotensin gene expression and behavioral responses following

  Engineering Websites

Summary: +/­ and D3­/­ mice. Similarly, acute cocaine and amphetamine induced NT mRNA expression in the nucleus, amphetamine, haloperidol, in situ hybridization, behavioral sensitization INTRODUCTION The administration of psychostimulants such as cocaine or amphetamine, and antipsychotics like haloperidol, promotes the expression


165

Evaluation of Genetic Variability in the Dopamine Receptor D2 in Relation to Behavioral Inhibition and Impulsivity/Sensation Seeking

  Biology and Medicine Websites

Summary: and Impulsivity/Sensation Seeking: An Exploratory Study With d-Amphetamine in Healthy Participants Ajna Hamidovic in the DRD2 gene (DRD2) in healthy volunteers (N 93). Participants received placebo or d-amphetamine measure of impulsivity. We secondarily evaluated the DRD2 SNPs in relation to response to d-amphetamine

Gilad, Yoav

166

Toward a Neuro-Cognitive Animal Model of the Cognitive Symptoms of Schizophrenia: Disruption of Cortical

  Biology and Medicine Websites

Summary: of Cortical Cholinergic Neurotransmission Following Repeated Amphetamine Exposure in Attentional Task of amphetamine (AMPH) and following challenges with AMPH. In non-performing rats, pretreatment with AMPH did advance online publication, 14 February 2007; doi:10.1038/sj.npp.1301352 Keywords: amphetamine; attention

Bruno, John P.

167

Small Effect of Dopamine Release and No Effect of Dopamine Depletion

  Biology and Medicine Websites

Summary: D2 radioligand; D-amphetamine; a-methyl-para-tyrosine; phasic; tonic; PET ABSTRACT Molecular imaging]fallypride and (2) both D-amphetamine-induced and a-methyl-p-tyrosine (AMPT)-induced changes in dopamin release studies at baseline and fol- lowing oral D-amphetamine administration (0.5 mg/kg) and oral AMPT

Shen, Jun

168

Physiology & Behavior, Vol. 66, No. 4, pp. 639643, 1999 1999 Elsevier Science Inc.

  Biology and Medicine Websites

Summary: associated with the administration of rewarding pharmacological compounds [i.e., amphetamine (AMPH of pharmacological reward. © 1999 Elsevier Science Inc. Reward Vocalization Rat Amphetamine Morphine CAREFUL of the dopaminergic ag- onist amphetamine (AMPH), which is thought to enhance positive affect in low doses, increases

Knutson, Brian

169

Brain Research, 490 (1989) 255-267 255 D2-agonist quinpirole induces perseveration of routes and

  Biology and Medicine Websites

Summary: , stereotyped in route, but free in movement. This profile resembles behavior under low doses of amphetamine but not the behavior under either apomorphine or high doses of amphetamine. Thus, contrary to the current view. Schiorring31 provided systematic evidence that one component of amphetamine-induced stereo- typed behavior

Golani, Ilan
1989-01-01

170

BEHAVIORAL NEUROSCIENCE Dopamine or opioid stimulation of nucleus accumbens

  Biology and Medicine Websites

Summary: , USA 2 Department of Psychology, University of Michigan, Ann Arbor, MI, USA Keywords: amphetamine amphetamine microinjection) vs. mu opioid stimulation [by d-Ala, nMe- Phe, Glyol-enkephalin (DAMGO of incentive salience. Cue-triggered `wanting' in PIT was enhanced by amphetamine or DAMGO microinjections

Berridge, Kent

171

ORIGINAL INVESTIGATION Memory and psychostimulants: modulation of Pavlovian

  Biology and Medicine Websites

Summary: by amphetamine in C57BL/6 mice Suzanne C. Wood & Stephan G. Anagnostaras Received: 15 April 2007 /Accepted: 22 study examined the effects a range of doses (0.005­8 mg/kg) of D-amphetamine sulfate on cued administered with a moderately high dose of amphetamine (8 mg/kg) pre-training, typical of what addicts might

Anagnostaras, Stephan

172

Brain Research 894 (2001) 354358 www.elsevier.com/locate/bres

  Biology and Medicine Websites

Summary: between the effects of intra-accumbens administration of amphetamine and exposure to a novel environment Previous research has demonstrated an interaction between the effects of amphetamine and exposure, the administration of intra-accumbens amphetamine was hypothesized to potentiate the increase in cortical

Bruno, John P.
2001-01-01

173

The Activity-Regulated Cytoskeletal-Associated Protein Arc Is Expressed in Different StriosomeMatrix Patterns Following

  Biology and Medicine Websites

Summary: ­Matrix Patterns Following Exposure to Amphetamine and Cocaine Andrew Tan, Rosario Moratalla, *Gregory L. Lyford to two psychomotor stimulants, cocaine and amphetamine. Cocaine induced arc in striatal neurons that were broadly distributed within both striosome and matrix compartments of the caudo- putamen. Amphetamine also

Graybiel, Ann M.

174

Behavioural Brain Research 153 (2004) 171180 Research report

  Environmental Sciences and Ecology Websites

Summary: . The first set of experiments demonstrated that intramuscular injections of cocaine and amphetamine have. Amphetamine and, to a lesser extent, cocaine were both found to serve as rewards when their intra; Addiction; Amphetamine; Cocaine; Decapoda; Crustacea; Arthropoda 1. Introduction Invertebrate model systems

Huber, Robert
2004-01-01

175

Preprint Collection of Charles J. Wilson Self-Inhibition by Dopaminergic Neurons

  Biology and Medicine Websites

Summary: , University of Colorado, Boulder, CO 80302 USA The mechanisms of action of amphetamine and the antipsychotic. Amphetamine appears to act, in large measure, by promoting the release of catecholamines from central prominent behavioral effect of amphetamine administration in experimental animals is an induction

Wilson, Charles J.

176

Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway

  Biology and Medicine Websites

Summary: of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine Isabella Anna Moroz,a,1 of amphetamine leads to enduring augmentation of its behavioral-activating effects, enhanced dopamine (DA to a 2-week escalating-dose regimen of amphetamine prevents behavioral asymmetries of forelimb use

Schallert, Tim

177

Preprint Collection of Charles J. Wilson Self-inhibition By Dopaminergic Neurones: Disruption By (+/-)-alpha-methyl-

  Biology and Medicine Websites

Summary: (+)-Amphetamine sulphate infused directly into the substantia nigra, pars compacta, at low rates and in low to block amphetamine-induced release of dopamine from dopaminergic terminals in the neostriatum (Spector intravenous amphetamine administration (Bunney et al., 1973). Further, diencephalic transections ante- rior

Wilson, Charles J.

178

Drug Monitoring and Toxicology Two-Dimensional Gas Chromatography/ Electron-Impact Mass Spectrometry with Cryofocusing for Simultaneous Quantification of MDMA, MDA, HMMA, HMA, and MDEA in Human Plasma

  CiteSeer

Summary: (MDMA, or Ecstasy) is a popular recreational drug. Analysis of MDMA and metabolites in human plasma, particularly in pharmacokinetic studies, requires low limits of quantification. Two-dimensional GC/MS with cryofocusing is a chromatographic technique recognized for its increased selectivity and resolution. METHODS: This method simultaneously quantifies 3,4methylenedioxyethylamphetamine (MDEA), MDMA, and its metabolites, 3,4-methylenedioxyamphetamine

Erin A. Kolbrich; Ross H. Lowe; Marilyn A. Huestis

179

Development of human brain connectivity in health and disease

  University of California eScholarship Repository

Summary: as potential higher order interaction e?ects between alcoholfor higher order cognitive functions. Fetal alcohol spectrumalcohol-exposed group, chil- dren with prenatal methamphetamine exposure showed higher

Colby, John Benjamin
2012-01-01

180

Minimal Non-Deterministic xor Automata Jean Vuillemin, Nicolas Gamma

  Computer Technologies and Information Sciences Websites

Summary: -deterministic transitions. Each automaton X and M = mda L is a strong normal form SNF: L = L mxa L = mxa L mda L = mda L A exp lin lin With such SNF [2], one maps different states of the MDA to different com- puter memory

Vuillemin, Jean

181

DIRECTORIO DE EXTENSIONES TELEFONICAS NUMERO CONMUTADOR: 942-94-00

  Mathematics Websites

Summary: . Director 9401 (999)9429401 decoss@mda.cinvestav.mx A MARTINEZ AGUILAR, Maria Antonieta Asistente del@mda.cinvestav.mx A BORGES DZIB, Jorge Gabriel 2582 gborges@mda.cinvestav.mx A MARTINEZ AGUILAR, Ma. Antonieta 2367 tony. Investigador 9408 (999)9249408 agarcia@mda.cinvestav.mx H DOMINGUEZ AGUILAR, Mauricio, Dr. 2215 mauricio


182

Recommended Progression Commencing 2007 onwards

  Computer Technologies and Information Sciences Websites

Summary: DISCONTINUED NA MDA20004 (HAM211) New Media: The Telecommunications Revolution MDA10001, MDA10004 or approved of the Electronic Age DISCONTINUED Choose one of: COS20013 (HIT3323) Web Programming COS10005 DIG10004 (HAD122 Sem 2 DIG30002 (HAD302) Digital Media Project 2 GAM30001 MDA30006 (HALM320) Literature/Media Project

Liley, David

183

Drug type Common names Forms Method of administration

  CiteSeer

Summary: n The number of clandestine laboratories detected in Australia has stabilised. This may be partially due to several initiatives designed to reduce diversion of pseudoephedrine from the licit market. n Restrictions on the sale of pseudoephedrine are likely to result in increased importation attempts as criminal groups attempt to source offshore supply. Alternatively, criminals may resort to other crimes to source pseudoephedrine domestically. n Amphetamine-type stimulant (ATS) arrests continued to increase and accounted for 15 percent of all drug arrests nationally. The number of ATS arrests was second only to cannabis arrests. Main Forms Amphetamine is a stimulant that is synthetically derived from betaphenethylamine, 1 to form a substance similar to the naturally occurring stimulant ephedrine and the hormone adrenalin. The term ‘amphetamines ’ is a generic name for a range of amphetamine-type stimulants (ATS), including amphetamine and methylamphetamine, 2 but generally excluding MDMA (3,4-methylenedioxymethylamphetamine, also known as ‘ecstasy’) and other amphetamine

Key Points

184

Facilitation of efficient search of an unbaited radial-arm maze in rats by D1, but not D2, dopamine receptors

  Biology and Medicine Websites

Summary: , increased the number of novel arms chosen in the first eight arms entered. Treatment with 0.1 mg/kg sc D-amphetamine following a test day with a 1.0 mg/kg dose. The 0.1-mg/kg amphetamine-induced facilitation was blocked preparatory behavior. D 2001 Elsevier Science Inc. All rights reserved. Keywords: SKF81297; Amphetamine; SCH

Timberlake, William D.

185

The College reserves the right to make changes in application deadlines and requirements for admission, curriculum, standards for advancement and graduation, tuition, fees, and rules and regulations. Please check back

  Geosciences Websites

Summary: for Amphetamines, Cocaine Metabolites, Marijuana Metabolites, Opiates, Phencyclidine, Barbiturates, Benzodiazepines these standards due to the functional limitations from disability, such as physical, sensory, medical, learning

Meyers, Steven D.

186

Journal Name Manuscript No. BDispatch: July 31, 2009 Journals: GBB

  Biology and Medicine Websites

Summary: to methamphetamine (MA). Mice were injected with saline (days 1 and 2) and MA (day 3; 2 mg/kg i.p.). We analyzed activity, methamphetamine, opioid, psychostimulant, QTL, stimulants Received 14 December 2008, revised 26 region critical for drug reward. Differences in the sensitivity to the locomotor activating effects

Gilad, Yoav

187

Available online at www.sciencedirect.com Cortico-striatal representation of time in animals and humans

  Biology and Medicine Websites

Summary: to the clock- speed enhancing effects of methamphetamine in hetero- zygous mice, indicating that excess levels of indirect dopamine (DA) agonists such as cocaine and methamphetamine produce pro- portional leftward shifts effect [4 ]. The D2 receptor is crucial to the mediation of these pharmacological effects [5

Cossart, Rosa

188

MethMorph: Simulating Facial Deformation Due to Methamphatamine Usage

  Mathematics Websites

Summary: are common side effects of meth usage. MethMorph fully automates the process of thin- ning the face Introduction Methamphetamine abuse contributed an economic burden of $23.4 billion to the United States in 2005 meth use among teenagers in Montana [2]. This marketing campaign uses many images of methamphetamine


189

Mining Higher-Order Association Rules from Distributed Named Entity Databases

  Computer Technologies and Information Sciences Websites

Summary: for effective distributed information extraction and mining techniques. Recently, as the need to mine patterns enforcement and homeland defense. For example, methamphetamine use is the number one drug problem in 60% of US Enforcement Administration (DEA) has conducted several operations to investigate the entire methamphetamine

Pottenger, William M.

190

Bio-Rad Laboratories u r I n e t O x I c O l O g y c O n t r O l s Urine Toxicology Controls

  Mathematics Websites

Summary: Level S2S+ Screening Cutoff Confirmatory Test Methods GC/MS, HPLC, LC/MS 0 -25% +25% Elevated Level C2 For Confirmatory Test Methods Such as GC/MS, HPLC and LC-MS/MS Amphetamines d-Amphetamine 100 375 625 375 625 1

Rodriguez, Carlos

191

BioMed Central Page 1 of 16

  Biology and Medicine Websites

Summary: microinjections of vehicle, CRF (250 or 500 ng/0.2 µl) or amphetamine (20 µg/0.2 µl). Lever pressing was assessed dose of CRF (500 ng) or amphetamine (20 µg) selectively enhanced the ability of Pavlovian reward cues

Berridge, Kent

192

Investigating the utility of combining Phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArrayTM genotyping

  University of Cambridge - Dspace

Summary: have investigated ?29 polymerase Multiple Displacement Amplification (MDA)-generated DNA product (MDA product), in combination with highly multiplexed BeadArray™ genotyping technology. As part of a large-scale BeadArray genotyping experiment...

Pask, Rebecca; Rance, Helen E; Barratt, Bryan J; Nutland, Sarah; Smyth, Deborah J; Sebastian, Meera; Twells, Rebecca C J; Smith, Anne; Lam, Alex C; Smink, Luc J; Walker, Neil M; Todd, John A
2004-07-27

193

unknown title

  CiteSeer

Summary: • There is an increasing trend in the use, including smoking, of crystal methylamphetamine (‘ice’) among young recreational drug users. • Australian amphetamine-type stimulant (ATS) supply is dominated by domestic clandestine production, primarily methylamphetamine manufacture; however, the increasing demand for high purity crystal methylamphetamine (‘ice’) may create an increase in attempted importations as well as in domestic clandestine production. • Clandestine laboratory production will continue to be associated with high levels of harm as a consequence of the production techniques and chemicals utilised. Key Points There is an increasing trend in the use, including smoking, of crystal methylamphetamine (‘ice’) among young recreational drug users. Australian amphetamine-type stimulant (ATS) supply is dominated by domestic clandestine production, primarily methylamphetamine manufacture; however, the increasing demand for high purity crystal methylamphetamine (‘ice’) may create an increase in attempted importations as well as in domestic clandestine production. Clandestine laboratory production will continue to be associated with high levels of harm as a consequence of the production techniques and chemicals utilised. Main Forms Amphetamine is a potent central nervous system stimulant. It is synthetically derived from betaphenethylamine to form a substance similar in structure and effect to the naturally occurring stimulant ephedrine and the hormone adrenalin. ‘Amphetamines ’ is a generic term referring to a range of ATS including amphetamine and methylamphetamine, 1 but generally excluding amphetamine analogues such as MDMA (ecstasy) (see Table 1). Table 1: Amphetamine-type stimulants commonly used in Australia

unknown authors

194

Neurotoxins: Free Radical Mechanisms and Melatonin Protection

  CiteSeer

Summary: actions of melatonin: aminolevulinic acid, cyanide, domoic acid, kainic acid, metals, methamphetamine, polychlorinated biphenyls, rotenone, toluene and 6-hydroxydopamine. Given the potent direct free radical scavenging activities of melatonin and its metabolites, their ability to indirectly stimulate

Russel J. Reiter; Lucien C. Manchester; Dun-xian Tan

195

InsideIllinoisJune 15, 2006 Vol. 25, No. 23

  Materials Science Websites

Summary: at experiences of children of methamphetamine abusers to help those children adjust to foster care and beyond of some friends, Siuts joined the UI Mas- ter Gardeners program. Siuts, an information technology

Lewis, Jennifer

196

A B C D E F G PSI # Date Time Location Incident Description Disposition

  Multidisciplinary Databases and Resources Websites

Summary: :30 Indian Fort Drug Offense 3 subjects arrested for intoxication and manufacturing methamphetamines Report Intoxicated Person Intoxicated non-student arrested for Publiuc Intoxication BPD Responded 4895 9/16/2012 21

Baltisberger, Jay H.

197

Gender-specific modulation of cocaine-induced place preference by 3,4-methylenedioxymethamphetamine

  Texas A&M University - TxSpace

Summary: In contemporary North-American culture, two frequently combined drugs possessing abuse liability are cocaine and "ecstasy" (+/- 3,4-methylenedioxy-methamphetamine [MDMA]). Each drug is a stimulant acting on brain dopamine sites, i.e., cocaine acts...

Diller, Anna Jean
2013-02-22

198

Neurotoxicity Research, Vol. 1, pp. 181-195 Reprints available directly from the publisher

  Biology and Medicine Websites

Summary: induce Lewy body formation, and mediate the synthesis of hydroxyl radical and oxyra- dical species's disease, Lewy bodies, Methamphetamine, Oxidative stress, VMAT, Substantia nigra, Tyrosinase Abbreviations: "'AD, Alzheimer's disease; BDNF, brainderived neurotrophic factor; CNS, central nervous system; DA

Sulzer, David

199

Clin Occup Environ MedChemical hazards in law enforcement

  CiteSeer

Summary: . Methamphetamine is an illegal stimulant that can be made with simple, over-the-counter ingredients. Other drugs manufactured in clandestine laboratories include sodium gamma hydroxybutyrate, lysergic acid diethylamide, methcathinone, methylenedioxymethamphetamine (ecstasy), and phencyclidine [1,2]. Most

Fabrice Czarnecki

200

This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research

  Chemistry Websites

Summary: contribute to the neurotoxic effects of the drug of abuse, methamphetamine, through oxidative and metabolic no effective treatment or cure. This defective enzyme, aspartoacylase (ASPA), plays a critical role in brain

Viola, Ronald

201

Copyright 2010 by the Genetics Society of America DOI: 10.1534/genetics.110.116863

  Biology and Medicine Websites

Summary: model that included polygenic effects to address this problem in our own analysis. Using a combination, subcentimorgan loci that were associated with methamphetamine sensitivity, (e.g., chromosome 18; LOD ¼ 10

Gilad, Yoav

202

Structural, Metabolic, and Functional Brain Abnormalities as a Result of Prenatal Exposure to Drugs of Abuse: Evidence from Neuroimaging

  University of California eScholarship Repository

Summary: Prenatal Exposure to Methamphetamine Mechanism of Action andmechanisms. Once inside the nerve terminals, methamphetaminemethamphetamine may be particularly toxic to the striatum, which makes sense in the context of its mechanism

Roussotte, Florence; Soderberg, Lindsay; Sowell, Elizabeth
2010-01-01

203

PSY 383 Psychoactive Drugs Summer Term 2014, University of Oregon

  Biology and Medicine Websites

Summary: , marijuana, and central nervous system depressants (e.g. alcohol) and stimulants (e.g. methamphetamine, and the societal, cultural, and legal contexts of drug use and use problems. This is a lot to cover in only four

Lockery, Shawn

204

Drug Use and Drug Policy in a Prohibition Regime

  University of California eScholarship Repository

Summary: half of cocaine clients have had one or more prior treatmenttreatment, 49 percent of methamphetamine, and 27 percent of smoked cocaine.cocaine consumption by 1 percent by investing $34 million in additional treatment

MacCoun, Robert; Martin, Karin D.
2008-01-01

205

Characterization of Membrane-Protein Interactions for the Leucine Transporter from Aquifex aeolicus by Molecular Dynamics Calculations

  Biology and Medicine Websites

Summary: is related with different disorders: epilepsy,18 depression, and Parkinson's disease.19 They are also targets of therapeutic agents such as anticonvulsants20 or addictive substances, for example, cocaine and amphetamines.21

Discher, Dennis

206

Psychopharmacology DOI 10.1007/s00213-008-1369-3 ORIGINAL INVESTIGATION When we enhance cognition with Adderall, do we sacrifice

  CiteSeer

Summary: Rationale Adderall (mixed amphetamine salts) is used by healthy normal individuals to enhance attention. Research with healthy normal participants and those with attention deficit hyperactivity disorder indicate a possible inverse relationship between attentional function and creativity. This

Martha J. Farah; Caroline Haimm; Geena Sankoorikal; Anjan Chatterjee
2008-01-01

207

Drug type Common names Forms Method of

  CiteSeer

Summary: • Methylamphetamine is the dominant form of amphetamine produced, imported and used in in the short term. detection risk. • High levels of harm associated with clandestine chemicals and production techniques involved.

Main Forms

208

Institute Policy Page 1 of 4 Substance Abuse June 28, 2013

  Engineering Websites

Summary: , but are not limited to, marijuana, heroin, cocaine, LSD, and amphetamines.) In addition, every employee is required substances or medication that may adversely affect the employee's ability to work in a safe, productive

Faraon, Andrei

209

Statistical analysis of GABAA receptor modulators' effects in rats with focus on memory improvement and reversing of

  Mathematics Websites

Summary: be effective in a putative animal model of schizophrenia; and, finally (iii) to develop a statistical model or amphetamine induced deficits which arguably reflect sensorimotor gating deficits seen in schizophrenia. Whilst......................................................................................................................................2 2.1. Schizophrenia and cognition


210

the road to Parkinson’s disease

  CiteSeer

Summary: Studies have implicated methamphetamine exposure as a contributor to the development of Parkinson’s disease. There is a significant degree of striatal dopamine depletion produced by methamphetamine, which makes the toxin useful in the creation of an animal model of Parkinson’s disease. Parkinson’s disease is a progressive neurodegenerative disorder associated with selective degeneration of nigrostriatal dopaminergic neurons. The immediate need is to understand the substances that increase the risk for this debilitating disorder as well as these substances’neurodegenerative mechanisms. Currently, various approaches are being taken to develop a novel and cost-effective anti-Parkinson’s drug with minimal adverse effects and the added benefit of a neuroprotective effect to facilitate and improve the care of patients with Parkinson’s disease. A methamphetamine-treated animal model for Parkinson’s disease can help to further the understanding of the neurodegenerative processes that target the nigrostriatal system. Studies on widely used drugs of abuse, which are also dopaminergic toxicants, may aid in understanding the etiology, pathophysiology and progression of the disease process and increase awareness of the risks involved in such drug abuse. In addition, this review evaluates the possible neuroprotective mechanisms of certain drugs against methamphetamine-induced toxicity. Key words: drug abuse, methamphetamine, neurotoxin, Parkinson disease, neuroprotection

Methamphetamine-induced Neurotoxicity; Bessy Thrash; Kariharan Thiruchelvan; Manuj Ahuja; Muralikrishnan Dhanasekaran

211

Micromachines 2013, 4, 321-332; doi:10.3390/mi4030321 micromachines

  Chemistry Websites

Summary: and longer fragment sizes than genome-wide amplification based on polymerase chain reaction (PCR). Although. Multiple displacement amplification (MDA) [4], based on 29 DNA polymerase and random primers, has been platforms have been developed for achieving single-cell isolation and a miniaturised MDA reaction

Zare, Richard N.

212

nature methods | VOL.7 NO.12 | DECEMBER 2010 | 943 correspondence

  Biology and Medicine Websites

Summary: unidirectional, skewing that would compromise quantitative comparisons (Supplementary Tables 2 and 4. MDA of picogram quantities of genomic DNA introduced pronounced skewing of most members of an eight identified in the unamplified controls were sig- nificantly skewed by MDA (Supplementary Table 2

Cai, Long

213

www.sciencetranslationalmedicine.org/cgi/content/full/6/229/229ra43/DC1 Supplementary Materials for

  Chemistry Websites

Summary: March 2014, Sci. Transl. Med. 6, 229ra43 (2014) DOI: 10.1126/scitranslmed.3007965 This PDF file includes MDA-MB-231 (blue) and Cal51 (red) cells peaks and then declines. n 1500 cells from 3 separate. (A) MDA-MB-231 cells expressing H2B-RFP (red) and GFP- tubulin (green) were filmed at 60× with 2

Raines, Ronald T.

214

Pablo ClementePablo Clemente--ColColn, Chief Scientistn, Chief Scientist STAR Science ForumSTAR Science Forum

  Geosciences Websites

Summary: RADARSATRADARSAT--1 SAR (CSA and MDA)1 SAR (CSA and MDA) ·· Present NASAPresent NASA--NOAANOAA--CSA agreement in force untilCSA agreement in force until NOV07 or RNOV07 or R--2 commissioning2 commissioning ·· NASA Representing NOAAby Craig Dobson, Eric Madsen Representing NOAA ·· CSA has funding for continued RCSA has

Kuligowski, Bob

215

S UPP LE ME NTARY INFORMATION WWW.NATURE.COM/NATURECELLBIOLOGY 1

  Biology and Medicine Websites

Summary: -miRNA in HeLa cells treated with DMSO (control) or BAF for 12 h. ATG5(1) and ATG5(2) represent results with two independent siRNA. (b) RT-qPCR analysis of MDA-231, T47D and MDA-435 cells treated with DMSO

Bedwell, David M.

216

ISSN 0103-9741 Monografias em Cincia da Computao

  Computer Technologies and Information Sciences Websites

Summary: - agent systems (MAS). MDA specifies a structured software development process divided in modeling stages libraries, virtual markets and information systems in general, such as [Braubach et al., 2004; He et al. In this paper, we propose a top-down MDA (Model Driven Architecture) [OMG, 2002] based approach for developing

Endler, Markus

217

Protein malnutrition associated with various oils (sunflower, soya, coconut

  Energy Storage, Conversion and Utilization Websites

Summary: Protein malnutrition associated with various oils (sunflower, soya, coconut and salmon) on platelet (MDA) which accelerate platelet aggregation. The aim of this study was to evaluate MDA production and platelet aggre- gation rate in young rats fed balanced (20% casein) or depleted (2% casein) protein diet as

Paris-Sud XI, Université de

218

The impact of luteal phase support on gene expression of extracellular matrix protein and adhesion molecules

  Biology and Medicine Websites

Summary: molecules in the human endometrium during the window of implantation following controlled ovarian stimulation with a GnRH antagonist protocol Yulian Zhao, Ph.D., M.D.,a Jairo Garcia, M.D.,a Lisa Kolp, M. Conclusion(s): Luteal phase support following controlled ovarian stimulation has a profound impact on the ECM

Terasaki, Mark

219

GESDOR A Generic Execution Model for Sharing of Computer-Interpretable Clinical Practice Guidelines

  Computer Technologies and Information Sciences Websites

Summary: ; Vimla L. Patel, PhD, DSca ; Edward H. Shortliffe, MD, PhDa a Department of Medical Informatics, Columbia Guidelines Dongwen Wang, PhDa ; Mor Peleg, PhDb ; Davis Bu, MDa ; Michael Cantor, MDa ; Giora Landesberg, MD, DScb ; Eitan Lunenfeld, MDb ; Samson W. Tu, MSb ; Gail E. Kaiser, PhDc ; George Hripcsak, MD, MSa

Peleg, Mor

220

WEIGHTED UNIFORM CONSISTENCY OF KERNEL DENSITY ESTIMATORS by Evarist Gine,1

  Mathematics Websites

Summary: -norm. 1. Research partially supported by NSF Grant No. DMS-0070382. 2. Research partially supported by NSA Grant No. MDA904-99-1-0031. 3. Research partially supported by NSA Grant No. MDA904-01-1-0027. 1 #12

Zinn, Joel

221

Regulus--free Spreads of PG(3; q) R. D. Baker*

  Mathematics Websites

Summary: algebra and the arithmetic of finite fields. * This work was partially supported by NSA grant MDA 904­95­H­1013 ** This work was partially supported by NSA grant MDA 904­94­H­2033. #12; Regulus--free Spreads 1

Ebert, Gary

222

Contemporary Mathematics Volume 00, 0000

  Multidisciplinary Databases and Resources Websites

Summary: . Support from the Institute for Advanced Study at Hebrew University, 1991­92. Supported by NSA grant MDA­93. · Supported by NSA grant MDA 904-89-H-2028. This paper is in final form and no version of it will be submitted

Fried, Michael

223

The locus of curves with prescribed automorphism group April 24, 2002

  Mathematics Websites

Summary: of the corresponding loci in M g , see Table 4. 1 Partially supported by NSA grant MDA904-01-1-0037 2 Partially supported by NSA grant MDA904-01-1-0023 3 Partially supported by NSF grant DMS-9970357 1 #12; The locus


224

Real Hilbertianity and the eld of totally real numbers Michael D. Fried y, Dan Haran z and Helmut Volklein

  Mathematics Websites

Summary: for Advanced Study at Hebrew University, 1991{92. y Supported by NSA grant MDA 14776 and BSF grant 87-00038. z Supported by Max-Planck-Institut fur Mathematik, Bonn, 1992{93. Supported by NSA grant MDA 904-89-H-2028. 1

Haran, Dan

225

Discrete Mathematics and Theoretical Computer Science DMTCS vol. 7, 2005, 313400 Enumeration of Binary Trees and

  Physics Websites

Summary: length The work was supported by NSF Grant DMS 05-03745 and NSA Grant MDA 904-03-1-0036. The work was supported by NSF Grants CCR-0208709 and DMS 05-03745, NIH Grant R01 GM068959-01, and NSA Grant MDA 904

Paris-Sud XI, Université de

226

A dominant nuclear mutation in Chlamydomonas identies a factor controlling chloroplast mRNA stability by acting on

  Renewable Energy Websites

Summary: A dominant nuclear mutation in Chlamydomonas identi®es a factor controlling chloroplast m 33 1 58 41 50 12; e-mail Wollman@ibbc.fr) Summary We have characterized a nuclear mutation, mda1-ncc1 mutations altering chloroplast gene expression described to date, mda1-ncc1 is a dominant mutation


227

On the Comparison of Multiple Signature LDA and Neural Network Based Broken Rotor Bar Detection Schemes in Induction Motors

  Engineering Websites

Summary: and different load conditions. Multiple Discriminant Analysis (MDA) and Artificial Neural Networks (ANN) provide (ANN) provide appropriate environments to develop such fault detection schemes because of their multi on a single MDA or a single ANN unit representing the complete motor operating load torque region. The second

Chow, Mo-Yuen

228

Safety signals as instrumental reinforcers during free-operant avoidance

  University of Cambridge - Dspace

Summary: by presenting footshocks in the absence of the lever, when the rats are under the influence of morphine, d-amphetamine or cen- tral infusions of the m-opioid agonist DAMGO (paired condi- tions). We therefore adopted an analogous procedure to revalue the safety... of affective facial expressions to pleasant tastes (Grill and Norgren 1978; Berridge 2000) are unaffected by systemic ad- ministration of either DA antagonists (Treit and Berridge 1990; Pecin˜a et al. 1997) or central infusions of d-amphetamine in the nucleus...

Fernando, A. B. P.; Urcelay, G. P.; Mar, A.C.; Dickinson, A.; Robbins, T.W.
2014-07-14

229

exchange program's effectiveness, but its fieldwork will yield data relevant to other research questions as well.

  Engineering Websites

Summary: accounts of how individuals manage their day- to-day existence. But Hoffer also incorporates ethnographic abuse (niDa) awarded Hoffer a five-year, $1.6 million grant in 2009 to study the methamphetamine market expertise in ethnographic methods and his innovative use of ethnographic data as the basis for the computer

Rollins, Andrew M.

230

Neurobiology of Learning and Memory 78, 610624 (2002) doi:10.1006/nlme.2002.4099

  Biology and Medicine Websites

Summary: S. Fowler, Gene-Jack Wang,* and Rita Z Goldstein* *Medical Department and Chemistry Department of National Drug Control Policy. Address correspondence and reprint requests to Nora D. Volkow, Medical in the human brain. We have investigated cocaine, heroin, marijuana, and methamphetamine (METH) abusers

Goldstein, Rita
2002-01-01

231

Alaska Justice Forum 18(3), Fall 2001 1 INSIDE THIS ISSUE

  Mathematics Websites

Summary: 2000 Matthew Giblin The Arrestee Drug Abuse Monitoring (ADAM) project is a national study Please see Aspects of drug use, page 6 Aspects of Drug Use: Arrestees in Anchorage, 2000 Male arrestees 0 0 0 0 50 100 Asian 4 4 25 50 25 50 0 0 0 0 25 0 1999 Opiates Methamphetamine Any of 10 drugs 2000

Pantaleone, Jim

232

Remember that a professional supervisory relationship does not mean an I want to improve my com-

  Materials Science Websites

Summary: be completely right. There are signs and symptoms common to all substances of abuse. Depending on the workplace of methamphetamine use other than absenteeism. This is true with other substances of abuse as well. You may never and hallucinations are also possible. The longer a person has been addicted, the more intolerable their withdrawal

Alpay, S. Pamir

233

Nathaniel Daw Associate Professor, Center for Neural Science and Department of Psychology,

  Biology and Medicine Websites

Summary: , Shohamy; 9/2009-9/2014) "Learning to avoid pain: Computational mechanisms and application to methamphetamine abuse" Human Frontiers Science Program Grant RGP0036/2009-C (PIs Nakamura, Daw, Cools; 12 in the human brain: Cognitive and computational mechanisms" McDonnell Foundation Scholar Award (Daw; 9

Daw, Nathaniel

234

ORIGINAL ARTICLE Disorders of compulsivity: a common bias towards

  Biology and Medicine Websites

Summary: OPEN ORIGINAL ARTICLE Disorders of compulsivity: a common bias towards learning habits V Voon1 of either mechanism, we show a bias towards model-free (habit) acquisition in disorders involving both natural (binge eating) and artificial (methamphetamine) rewards, and obsessive-compulsive disorder

Dayan, Peter

235

Neuroscience and Biobehavioral Reviews 35 (2011) 498515 Contents lists available at ScienceDirect

  Biology and Medicine Websites

Summary: of mesocorticolimbic dopamine in regulating interactions between drugs of abuse and social behavior Kimberly A. Young Received in revised form 8 June 2010 Accepted 11 June 2010 Keywords: Maternal behavior Social play Pair bonding Aggression Sexual behavior Drug addiction Psychostimulants Cocaine Amphetamine Opiates Morphine

Hull, Elaine

236

Neuroscience Letters 468 (2010) 1822 Contents lists available at ScienceDirect

  Biology and Medicine Websites

Summary: Letters journal homepage: www.elsevier.com/locate/neulet Amphetamine and extinction of cued fear Stephanie the acquisition of cued fear. The current experiment sought to expand these findings to the extinction of cued-traumatic stress disorder. If extinction reflects new learning, one might expect drugs that enhance the acquisition

Anagnostaras, Stephan
2010-01-01

237

103:1295-1303, 2010. First published Jan 6, 2010; doi:10.1152/jn.00734.2009J Neurophysiol Esther Udina, Jessica D'Amico, Austin J. Bergquist and Monica A. Gorassini

  Biology and Medicine Websites

Summary: as an estimate of the synaptic input to the higher-threshold (test) motor unit. Generally, PICs are initiated;Amphetamine Increases Persistent Inward Currents in Human Motoneurons Estimated From Paired Motor Engineering and 3 Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada Submitted 12

Gorassini, Monica

238

Crise audiogne chez la souris selon la souche et le sexe : influence de la ration magnsique et des neuromdiateurs

  Computer Technologies and Information Sciences Websites

Summary: , magnesium deficiency and brain biogenic amines on audiogenic seizures in mice. Mice of the DBA/2/M strain seizures can be obtained with experimental magnesium deficiency. When AKR/R, OF1 and C57BL/R mice were deprived of magnesium for 15 or 21 days, they manifested an audiogenic attack only when given amphetamine

Boyer, Edmond

239

CURRICULUM VITAE Arpi Minassian, Ph.D.

  Biology and Medicine Websites

Summary: Dougall, A., Minassian, A., Jenkins, M., & Braff, D. (1995). Amphetamine on Rorschach measures in normal.D. 5/01 Clinical Psychology San Diego, CA M.A. 7/95 Academic Appointments 7/10-present Associate in Biological Psychiatry and Neuroscience. Mentors: Eric Turner, M.D., Ph.D., & William Perry, Ph.D. 7

Squire, Larry R.

240

Quantitative Analysis of Pre-and Postsynaptic Sex Differences in the Nucleus Accumbens

  Plasma Physics and Fusion Websites

Summary: Institutes of Health; Grant numbers: F32 DA 025449 (to P.M.F.) and R01 DA 020492 (to C.S.W.). Current address substances differ between males and females (reviewed in Roth et al., 2004; Becker and Hu, 2008; Swendsen et such as cocaine or amphetamine. These studies show that both behavioral sensitization (Hu and Becker, 2003

Woolley, Catherine

241

This Week in The Journal F Cellular/Molecular

  Biology and Medicine Websites

Summary: , amphetamine reduces efflux through the mutant receptor. Although the mutation described is extremely rare-Matter Plasticity JaninaBoyke,JoennaDriemeyer, ChristianGaser,ChristianBu¨chel,and ArneMay (seepages7031 in hippocampus and nucleus accumbens compared to controls. As in young adults, these gray-matter changes were

Gaser, Christian

242

BRIEF REPORT Myocardial Infarction Associated with Adderall XR and Alcohol Use in a Young Man

  CiteSeer

Summary: Adderall, consisting of a mixture of amphetamine salts and dextroamphetamine salts, is a prescription drug for attention deficit/hyperactivity disorder (ADHD) and narcolepsy. Labeled or unlabeled use of Adderall is gaining popularity among young children and college students. Although it is rare

Daniel Miller; Melvyn Bleiberg

243

Abuse and Mental Health Ser vices

  CiteSeer

Summary: , mar-ket, and sell OxyContin through illegal means.2 The National Center on Addiction and Substance Abuse at Columbia University found that during the same year almost 3 % of college students abused stimulants, such as methylphenidate (Ritalin, Novar-tis) and amphetamine (Adderall, Shire).3 According

unknown authors
2007-01-01

244

East and Southeast Asia..........................................................................................................7

  CiteSeer

Summary: Disclaimer: This document has not been formally edited. The boundaries, names and designations used do not imply of ? cial endorsement or acceptance by the United Nations. Patterns and Trends of Amphetamine-Type Stimulants and Other Drugs: Asia and the Paci?c

Global Smart Programme; Dr. Justice Tettey; East Asia Team; Mr. Shawn Kelley; The Global; Smart Programme; South Asia
2010-01-01

245

header for SPIE use Machine Learning Methods for Quantitative Analysis of Raman

  Computer Technologies and Information Sciences Websites

Summary: by Raman spectroscopy in the laboratory include cocaine,4 heroin, 5 and amphetamines in both solid results are presented for the problem of estimating the concentration of cocaine in solid mixtures composition,8 metabolites in urine,9 and cocaine. 10, 11 In our previous work, we have employed traditional

Madden, Michael

246

Neuroscience Vol. 14, No. 3, pp. 783-798, 1985 Printed in Great Britain

  Biology and Medicine Websites

Summary: .00 Pergamon Press Ltd 0 1985IBRO THE MORPHOGENESIS OF STEREOTYPED BEHAVIOR INDUCED BY THE DOPAMINE RECEPTOR to activate the behavior but also to shut it down. Apomorphine- and amphetamine-induced behavior is usually using the Eshkol-Wachman Movement Notation'"s" to analyse apomorphine-induced be- havior in rats

Golani, Ilan

247

Neuron, Vol. 42, 653663, May 27, 2004, Copyright 2004 by Cell Press Heterosynaptic Dopamine Neurotransmission

  Biology and Medicine Websites

Summary: Neuron, Vol. 42, 653­663, May 27, 2004, Copyright 2004 by Cell Press Heterosynaptic Dopamine Center configuration suggests that dopamine release, which isSeattle, Washington 98105 elicited or by dopamine-3 Department of Psychiatry releasing drugs such as amphetamine, may not only4 Center

Sulzer, David

248

From HEALTH TOPICS on the UHS Web site www.rochester.edu/uhs

  Biology and Medicine Websites

Summary: effects of meth, children born to meth users and addicts are also at an increased risk of child abuse for abuse and dependence. A derivative of amphetamine, meth was first developed in the early 20th century potential for abuse. Despite its classification and illegal status, meth has continued to be both produced

Mahon, Bradford Z.

249

Psychopharmacology (1995) 117: 443-452 O R I G I N A L I N V E S T I G AT I O N

  Biology and Medicine Websites

Summary: tested in a novel environment than in animals tested at home. In addition, animals tested in a novel environment showed greater sensiti- zation than animals tested at home, so the difference between the two response to the first injection o f amphetamine, and greater sensitization, i n animals tested in a novel

Anagnostaras, Stephan
1995-01-01

250

Dopamine transport currents are promoted from curiosity to

  Biology and Medicine Websites

Summary: Dopamine transport currents are promoted from curiosity to physiology David Sulzer1 and Aurelio these neurons by activating an uncoupled Cl---- conductance that is mediated by the dopamine uptake transporter importantly to understanding amphetamine action. The dopamine uptake transporter (DAT) is the primary site

Sulzer, David

251

Alcohol, tobacco and recreational drug use and the risk of non-Hodgkin's lymphoma

  CiteSeer

Summary: (trend P = 0.03), with risk 50 % lower among those consuming five or more drinks per week than among non-drinkers. Cocaine, amphetamines, Quaaludes and lysergic acid diethylamide (LSD) were each associated with a significantly increased risk of NHL in men with risk greater among those with more frequent

Ra Nelsonl; Am Levine; G Marks; L Bernstein

252

Abstract Rationale: Previous studies on the attentional effects of repeated psychostimulant administration in rats

  Biology and Medicine Websites

Summary: administration in rats suggested the possibility that these effects are mediated via increases in the efficacy the excitability of basal forebrain corticopetal cholinergic projections, thereby supporting speculations about of amphetamine stimulated ACh and DA efflux and locomotor behavior in both groups. The pretreatment

Bruno, John P.

253

Life Sciences, Vol. 35, pp. 1297-1300 Printed in the U.S.A.

  Biology and Medicine Websites

Summary: ANOREXIC DRUGSTO SUPPRESSFOODCONSUMPTION DEPENDSON THE NUTRIENT COMPOSITIONOF THE TESr DIET Peter L. Moses, isocaloric, isonitrogenous diets differing in carbohydrate content. Three of the test agents, d- amphetamine reduced food consumption whether the test diet was rich (75% dextrin) or poor (25% dextrin

Wurtman, Richard

254

Sensitivity of liver metabolism from jerboa (Jaculus orientalis) to ciprofibrate, a peroxisome proliferator

  Physics Websites

Summary: of peroxisomal catalase activity and an increase in MDA (malondialdehyde) level (stress biomarker). Moreover containing enzymes involved in the oxidative metabolism (H2O2-producing oxidases, peroxidase/catalase, Mn

Paris-Sud XI, Université de

255

Flow Analysis for Verifying Speci cations of Concurrent and Distributed Software

  Computer Technologies and Information Sciences Websites

Summary: University of Massachusetts Manhattan, KS 66506 Amherst, MA 01003 dwyer@cis.ksu.edu clarke was supported by the Advanced Research Projects Agency under Grant MDA972-91-J-1009, the O ce of Naval Research

Massachusetts at Amherst, University of

256

Flow Analysis for Verifying Specifications of Concurrent and Distributed Software \\Lambda

  Computer Technologies and Information Sciences Websites

Summary: University University of Massachusetts Manhattan, KS 66506 Amherst, MA 01003 dwyer@cis.ksu.edu clarke This work was supported by the Advanced Research Projects Agency under Grant MDA972­91­J­1009, the Office

Massachusetts at Amherst, University of

257

AND HAMSAVEENA 4

  CiteSeer

Summary: Background Aging is associated with changes in physical characteristics and decline of many physiological functions. There are several conflicting and inconsistent data reported on the relationship between individual antioxidants and aging. Hence, the present study was designed to study the significance of malondialdehyde: total antioxidant capacity (MDA:TAC) ratio as novel indicator of oxidative stress in aging. Methods In this study, we determined the serum MDA and TAC on healthy non-obese males. Healthy subjects were classified into 3 groups, elderly (>50 yrs), middle-aged (35-49 yrs) and young group (20-34 yrs). Results MDA:TAC ratio increased with advancing age. Oxidative stress correlated with decrease in waist-to-hip ratio. Conclusion These results are suggestive of oxidative stress with advancing age. MDA:TAC ratio can be a useful indicator to monitor and optimize antioxidant therapy which may reduce morbidity and perhaps increase the healthy, useful life span of an individual.

Suresh D R; Sendil Kumaran; Annam V

258

IEEE PHOTONICS TECHNOLOGY LETTERS, VOL. 17, NO. 1, JANUARY 2005 187 Dispersion-Enhanced Photonic Crystal Fiber Array

  Engineering Websites

Summary: was supported by the Air Force Office of Scientific Research (AFOSR) and by the Missile Defense Agency (MDA will be decreased proportionally. Conventional single-mode fibers (SMFs), based on weakly guiding structures

Chen, Ray

259

Terahertz radiation by optical rectification in a hydrogen-bonded organic molecular ferroelectric crystal, 2-phenylmalondialdehyde

  CERN Preprints

Summary: Terahertz radiation by optical rectification has been observed at room temperature in a hydrogen-bonded organic molecular ferroelectric crystal, 2-phenyl malondialdehyde (PhMDA). The radiated electromagnetic wave consisted of a single-cycle terahertz pulse with a temporal width of $\\sim$ 0.5 ps. The terahertz radiation amplitude divided by the sample thickness in PhMDA was nearly equivalent to that in a typical terahertz wave emitter ZnTe. This is attributable to a long coherence length in the range of 130 $\\sim$ 800 $\\mu$m for the terahertz radiation from PhMDA. We also discussed the possibility of PhMDA as a terahertz wave emitter in terms of the phase-matching condition.

Guan, W; Sotome, M; Kinoshita, Y; Takeda, R; Inoue, A; Horiuchi, S; Okamoto, H
2014-01-01

260

MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progression

  Biology and Medicine Websites

Summary: activity of SWI SNF proteins. In fact, Brahma (BRM), a trx-G family gene, itself, encodes a SWI SNF ATPase domain. BRM recruits more than seven other SWI SNF proteins to form a 2-MDa complex that is found

Strominger, Jack L.

261

Realistic Modeling of Simple and Complex Cell Tuning in

  Biology and Medicine Websites

Summary: of the architecture at the top level to replicate shape tuning as well as shift and size invari- ance properties of Naval Research (DARPA) Contract No. MDA972-04-1-0037, Office of Naval Research (DARPA) Contract No. N

Riesenhuber, Maximilian

262

Structural studies of large architectural nucleoporins and coat proteins

  MIT - DSpace

Summary: The Nuclear Pore Complex (NPC) is a ~50 MDa protein complex that forms the sole conduit for macromolecular transport across the nuclear envelope. It assembles from ~30 proteins, termed nucleoporins or nups, symmetrically ...

Whittle, James Richardson Ross
2010-01-01

263

Genomic Sequencing of Single Microbial Cells from Environmental Samples

  University of California eScholarship Repository

Summary: rearrangements can occur during the DNA amplification reaction.reaction enzymology to reduce bias and chimeric rearrangements.rearrangement (largely inversion-deletion events) per 20 Kb by the MDA reaction [

Ishoey, Thomas
2010-01-01

264

IEEE TRANSACTIONS ON MAGNETICS, VOL. 38, NO. 5, SEPTEMBER 2002 2607 RF Dynamics in Nanoparticle Systems With

  Materials Science Websites

Summary: was supported in part by the Defense Advanced Research Project Agency (DARPA) under Grant MDA 972. Tung, V. Kolesnichenko, J. Fang, and C. J. O'Connor are with the Advanced Materials Research Institute

Spinu, Leonard

265

Expression of a Dominant Negative CELF Protein In Vivo Leads to Altered Muscle Organization, Fiber Size, and

  Biology and Medicine Websites

Summary: organization and muscle fiber properties affected in myotonic dystrophy. This lends further evidence was supported by grants to A.N.L. from the Muscular Dystrophy Association (Development Grant MDA3812


266

If a student does not have a co-major it is recommended they take: STA30001 (LSQ331) Applied Statistics project or BUS30008 (LZZ331) Work Integrated Learning Project.

  Computer Technologies and Information Sciences Websites

Summary: Cultures: Perspectives on Science and Technology (replaced LSM101 Cultural Perspectives on Science and Technology) Nil Affiliated Studies MDA10001 (HAM100) Introduction to Media Studies (replaced LSM103

Liley, David

267

Welcome to the Life Sciences Innovation Showcase In Collaboration with

  Power Transmission, Distribution and Plants Websites

Summary: to diagnose it and stop it from happening #12;Our Discovery · We have identified a single enzyme called mutating enzyme APOBEC3B Ovarian cancer cell lineBreast cancer cell line MDA-MB-453 #12;APOBEC3B

Amin, S. Massoud

268

DEPARTAMENTO DE ECOLOGA HUMANA

  Mathematics Websites

Summary: del Comportamiento, 1994) Universidad de Boston, EUA. Temas de investigación: Salud, nutrición y tradicional. Estado nutricional. Geografía de la salud. gbalam@mda.cinvestav.mx Eduardo Batllori Sampedro


269

MKV Carrier Vehicle Sensor Calibration

  MIT - DSpace

Summary: The Multiple Kill Vehicle (MKV) system, which is being developed by the US Missile Defense Agency (MDA), is a midcourse payload that includes a carrier vehicle and a number of small kill vehicles. During the mission, the ...

Plotnik, Aaron M.

270

"Pigments of Our Imagination: Anthropological Myths, Racial Archives and the Transnationalism of Apartheid"

  University of California eScholarship Repository

Summary: American and South African History, notes that, “Despite some superficial similarities…the differences between Jim Crow and “native segregation” or “separate development”development of the South African nation, Mda offers a critique of twenty-first century American

Sides, Kirk Bryan
2014-01-01

271

Cold Spring Harbor Laboratory Press NATURE METHODS | VOL.2 NO.7 | JULY 2005 | 557 CLASSIC PROTOCOL

  Chemistry Websites

Summary: ) DNA by electrophoresis through a nondenaturing polyacrylamide gel. The protein retards the mobility greater than 1 MDa in mass are difficult to resolve and migrate quite slowly in the native polyacrylamide

Cai, Long

272

Brett A. Buchholz Annelise E. Barron

  Materials Science Websites

Summary: years, ultrahigh weight-average molar mass (Mw) linear polyacrylamide (LPA) with Mw values of 10­20 MDa-491-3728 Abbreviations: LPA, linear polyacrylamide; GPC, gel permeation chromatography; LALLS, low-angle laser light

Barron, Annelise E.

273

Location and Timing KTN / Mobile Data Association: 6 March 2008

  Physics Websites

Summary: Davis Romtrac GPS solutions for Lone Workers Mike Hawkes M-Commerce and Security Director MDA Protecting of equipment, legislation, and security will be needed to roll out such a system? An area of concern to us all


274

Development of Microbial Genome-Probing Microarrays Using

  Biology and Medicine Websites

Summary: genomesfromkeymicrobesinvolvedindichloromethane(DCM)- dechlorinating enrichment as microarray probes to uncover the bacterial population dynamics bacteria with 80.3-99.4% similarity to 16S rRNA genes of cultivated bacteria. The digital MDA-GPMmethodsuccessfullymonitoredthedynamicsofDCM

Bae, Jin-Woo

275

Ultra-fast Object Recognition from Few Spikes

  Biology and Medicine Websites

Summary: was sponsored by a Whiteman Fellowship and the Government grant from the Office of Naval Research (DARPA) Contract No. MDA972-04-1-0037, Office of Naval Research (DARPA) Contract No. N00014-02-1-0915, National

Poggio, Tomaso

276

Fast Rates for Regularized Least-squares Algorithm

  Biology and Medicine Websites

Summary: (CSAIL). This research was sponsored by grants from: Office of Naval Research (DARPA) Contract No. MDA972-04-1-0037, Office of Naval Research (DARPA) Contract No. N00014-02-1-0915, National Science Foundation (ITR

Poggio, Tomaso

277

Combining Variable Selection with Dimensionality Reduction

  Biology and Medicine Websites

Summary: (CSAIL). This research was sponsored by grants from: Office of Naval Research (DARPA) Contract No. MDA972-04-1-0037, Office of Naval Research (DARPA) Contract No. N00014-02-1-0915, National Science Foundation (ITR

Poggio, Tomaso

278

An Advanced Teleoperation Testbed , John Bares1

  Physics Websites

Summary: . br@cs.cmu.edu 2. DARPA TTO Project Manager 3. RovnoTech Abstract: Due to the technology available Research Projects Agency TTO Program under DARPA CMO Agreement MDA972-01-9-0005. The views and conclusions

Paris-Sud XI, Université de

279

April 5, 2010 Department of Mathematics Telephone: 319/335-0717

  Biology and Medicine Websites

Summary: . · 3/2006-3/2008 NSA grant, PI, Bounds for automorphic L-functions, their zeros, func- toriality University. · 2/20032/2005 NSA Grant MDA904-03-1-0066, PI, Zeros and Subconvexity of L- Functions. · 12

Ye, Yangbo

280

A Survey of Service Oriented Development Methodologies

  Computer Technologies and Information Sciences Websites

Summary: of Sheffield Regent Court, 211 Portobello Street, Sheffield, S1 4DP, UK a.simons@dcs.shef.ac.uk Abstract-based MDA, wrap legacy, componentize legacy, data-driven, and message-driven. Papazoglou et al [3] provide

Simons, Anthony J. H.

281

Building Songs 11

  University of Cambridge - Dspace

Summary: County, Dkar mdzes Tibetan Autonomous Prefecture, Sichuan Province, China. Name(s), age, sex, place of birth of performer(s) Male villagers from Phu ma, Mda' ma and Hyo ba Townships, Sde dge County, Dkar mdzes Tibetan Autonomous Prefecture...

Zla ba sgrol ma
2009-11-06

282

Building Songs 10

  University of Cambridge - Dspace

Summary: County, Dkar mdzes Tibetan Autonomous Prefecture, Sichuan Province, China. Name(s), age, sex, place of birth of performer(s) Male villagers from Phu ma, Mda' ma and Hyo ba Townships, Sde dge County, Dkar mdzes Tibetan Autonomous Prefecture...

Zla ba sgrol ma
2009-11-06

283

Antioxidant enzyme gene transfer for ischemic diseases

  University of California eScholarship Repository

Summary: increase in liver SOD and catalase activity, and to a 50-The elevated SOD or catalase activity in the liver protectedliver MDA content. These findings coincided with a striking increase in SOD or catalase activity,

Wu, Jian
2009-01-01

284

A Hellytype theorem for hyperplane transversals to wellseparated convex sets

  Computer Technologies and Information Sciences Websites

Summary: York, NY 10031, U.S.A. (jegcc@cunyvm.cuny.edu). Supported in part by NSA Grant MDA904­98­I­0032 and PSC, U.S.A. (pollack@cims.nyu.edu). Supported in part by NSF Grants CCR­9711240 and CCR­9732101 and NSA@cis.ohio­state.edu). Supported in part by NSA Grant MDA904­97­I­0019. or hyperplane, that intersects every member of S . We

Aronov, Boris

285

© Jared C. Hardy, 2007BEHAVIORAL CORRELATES OF UNILATERAL DOPAMINE DEPLETION IN THE MPP+ RAT MODEL OF PARKINSON’S DISEASE

  CiteSeer

Summary: Conventional cylinder test measures have limited sensitivity in determining hemiparkinson rat forelimb use asymmetry and approximating substantia nigra (SN) dopaminergic neuron loss. This thesis investigates which cylinder test measures of hemiparkinson rat forelimb use asymmetry best predict methamphetamine-induced rotation and extent of dopaminergic neuron loss. Long-Evans rats were cylinder-tested after unilateral 1-methyl-4-phenylpyridinium (MPP+)-induced SN dopamine depletion. Time and count of numerous forepaw wall contact patterns were documented for MPP+ hemiparkinson rats and sham-operated controls using frame-by-frame video analysis, then regressed against methamphetamine-induced rotation and tyrosine hydroxylasepositive neuron depletion. Severely dopamine-asymmetric rats initiated movements slower and less often with the contralateral-to-lesion forepaw, indicating that the cylinder test may be used to assess Parkinson Disease motor impairments of bradykinesia and akinesia. Several new time and count asymmetry measures may improve cylinder test

Jared C. Hardy; Jared C. Hardy

286

Preventing Theft of Anhydrous Ammonia

  Texas A&M University - TxSpace

Summary: ammonia containers and release large amounts of the chemical into the air, exposing farmers, agricultural workers and rescue workers to the toxic gas. When thefts are aborted or when thieves are overcome by the fumes, small storage containers... reasonable attempt to protect against tampering and theft. Methamphetamine Labs Illegal drug manufacturers sometimes set up tempo- rary labs in remote, wooded areas on large farms. These labs are often small and mobile, allowing drug manufac- turers to go...

Smith, David
2004-09-16

287

ArTS & HUMANiTiES Bradley’s Benzedrine Studies on Children with Behavioral Disorders

  CiteSeer

Summary: in 1937, psychiatrist Charles Bradley administered Benzedrine sulfate, an amphetamine, to “problem ” children at the Emma Pendleton Bradley Home in Providence, rhode island, in an attempt to alleviate headaches; however, Bradley noticed an unexpected effect upon the behavior of the children: improved school performance, social interactions, and emotional responses. Drawing on Bradley’s published articles on his experiments, this paper explores the historical context of his experiments and the effect this background had on the emerging field of child psychiatry. Bradley’s studies went largely ignored in the field of child psychiatry for nearly 25 years. However, they proved to be an important precursor to studies of amphetamines like ritalin and their use in conditions such as attention deficit hyperactivity disorder. Bradley’s Benzedrine trials were thus highly influential in shaping modern objective understandings of children with behavior disorders.

Madeleine P. Strohl

288

Authorship: Global SMART Programme Global team:

  CiteSeer

Summary: This document has not been formally edited. The designations employed and the presentation of the material in the document does not imply the expression of any opinion on the part of the United Nations concerning the legal staus of any country, territory, city or area under its authority or concerning the delimitations of its frontiers and boundaries. Patterns and Trends of Amphetamine-Type Stimulants and


2012-01-01

289

REVIEW Psychopharmacology of ADHD in pediatrics: current advances and issues

  CiteSeer

Summary: Abstract: Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder found in 3 % to 8 % of children and adolescents. An important part of ADHD management is psychopharmacology, which includes stimulants, norepinephrine reuptake inhibitors, alpha-2 agonists, and antidepressants. Medications with the best evidence-based support for ADHD management are the stimulants methylphenidate and amphetamine. A number of newer, long-acting stimulants are now available and a number of new medications are considered that are under current research.

Donald E Greydanus; Ahsan Nazeer; Dilip R Patel

290

Aspirin as a promoter of phenylpropanolamine-induced weight loss in lean and genetically obese (ob/ob) mice

  Texas A&M University - TxSpace

Summary: genetic conditions showed steady increases in body weight during the two ? week treatment period, with the obese mice showing greater daily consumption of food than the lean mice. Several explanations are discussed to account for these findings... in feeding behavior when amphetamine is administered acutely and chronically to lean and genetically obese mice. They found a dose-dependent decrease in the food intake of both lean and ob/ob mice. However, although ob/ob mice who were administered saline...

Lerma, Margaret Susan
1988-01-01

291

Can Massive Gravity Explain the Mass Discrepancy - Acceleration Relation of Disk Galaxies?

  CERN Preprints

Summary: The empirical mass discrepancy-acceleration (MDA) relation of disk galaxies provides a key test for models of galactic dynamics. In terms of modified laws of gravity and/or inertia, the MDA relation quantifies the transition from Newtonian to modified dynamics at low centripetal accelerations a_c < 10^-10 m/s^2. As yet, neither dynamical models based on dark matter nor proposed modifications of the laws of gravity/inertia have predicted the functional form of the MDA relation. In this work, I revisit the MDA data and compare them to four different theoretical scaling laws. Three of these scaling laws are entirely empirical, the fourth one - the "simple mu" function of Modified Newtonian Dynamics - derives from a toy model of gravity based on massive gravitons (the "graviton picture"). All theoretical MDA relations comprise one free parameter of the dimension of an acceleration, Milgrom's constant a_M. I find that the "simple mu" function provides a good fit to the data free of notable systematic residuals ...

Trippe, Sascha
2013-01-01

292

Self Organizing Mixture Network in Mixture Discriminant Analysis: An Experimental Study

  CiteSeer

Summary: Abstract—In the recent works related with mixture discriminant analysis (MDA), expectation and maximization (EM) algorithm is used to estimate parameters of Gaussian mixtures. But, initial values of EM algorithm affect the final parameters ’ estimates. Also, when EM algorithm is applied two times, for the same data set, it can be give different results for the estimate of parameters and this affect the classification accuracy of MDA. Forthcoming this problem, we use Self Organizing Mixture Network (SOMN) algorithm to estimate parameters of Gaussians mixtures in MDA that SOMN is more robust when random the initial values of the parameters are used [5]. We show effectiveness of this method on popular simulated waveform datasets and real glass data set.

Nazif Çal??; Murat Eri?o?lu; Hamza Erol; Tayfun Servi

293

VIROTHERAPY TARGETING BREAST CANCER STEMS CELLS BY USING ONCOLYTIC HERPS SIMPLEX VIRUS.

  CiteSeer

Summary: In the present study I isolated breast cancer stem cells from cell line MDA-MB231 by used CD44 MicroBeads separator. Cancer stem cells (CSCs) were identified by used PCR machine; here specific primers were designed for CD44 and CD24 genes, whereas CD44 positive for breast CSCs and CD24 negative CSCs. MDA-MB231 cells and breast CSCs treated with G47 ? vector. G47 ? showed highly effect on both kinds of cells by killing over 90 % of MDA-MB231 and over 80 % of the CSCs in vitro. Virus used as therapy demonstrated that pathogenic microorganisms can be modify genetically and use for targeting diseases and oHSV can be used for treatment breast CSCs that are still not understood. This study demonstrates that oHVS effective against breast cancer stem cells and could be a beneficial method for treating cancer stem cells expressed in breast cancer.

Maytham Abbas Abbodi

294

Web Data Mining Using An Intelligent Information System Design

  CiteSeer

Summary: Abstract — To use the large amounts of information efficiently on the Web to make the information processing intelligent, personalized and automatic is the most important applications of the current data mining technology. Model Driven Architecture (MDA) which is used for code generation has many benefits over traditional software development methods. An intelligent mining system of information is built with combining the data mining. In this paper, concept of Web data mining is introduced where the role of MDA is defined. MDA using J2EE (Java to Enterprise Edition) to describe behavior of agents are used in this proposed architecture. JADE (Java Agent Development Environment) Framework provides a standard for developing MAS (multi-agent systems). Also Agent’s Modeling Language (AUML) is being defined to effective implementation of defining agent roles.


295

Can Massive Gravity Explain the Mass Discrepancy - Acceleration Relation of Disk Galaxies?

  HEP - Phenomenology (arXiv)

Summary: The empirical mass discrepancy-acceleration (MDA) relation of disk galaxies provides a key test for models of galactic dynamics. In terms of modified laws of gravity and/or inertia, the MDA relation quantifies the transition from Newtonian to modified dynamics at low centripetal accelerations a_c < 10^-10 m/s^2. As yet, neither dynamical models based on dark matter nor proposed modifications of the laws of gravity/inertia have predicted the functional form of the MDA relation. In this work, I revisit the MDA data and compare them to four different theoretical scaling laws. Three of these scaling laws are entirely empirical, the fourth one - the "simple mu" function of Modified Newtonian Dynamics - derives from a toy model of gravity based on massive gravitons (the "graviton picture"). All theoretical MDA relations comprise one free parameter of the dimension of an acceleration, Milgrom's constant a_M. I find that the "simple mu" function provides a good fit to the data free of notable systematic residuals and provides the best fit among the four scaling laws tested. The best-fit value of Milgrom's constant is a_M = (1.06 +/- 0.05)*10^-10 m/s^2. Given the successful prediction of the functional form of the MDA relation, plus an overall agreement with the observed kinematics of stellar systems spanning eight orders of magnitude in size and 14 orders of magnitude in mass, I conclude that the "graviton picture" is sufficient (albeit probably not a necessary or unique approach) to describe galactic dynamics on all scales well beyond the scale of the solar system. This suggests that, at least on galactic scales, gravity behaves as if it was mediated by massive particles.

Sascha Trippe
2013-05-28

296

Excitation of Giant Monopole Resonance in $^{208}$Pb and $^{116}$Sn Using Inelastic Deuteron Scattering

  Nuclear Experiment (arXiv)

Summary: The excitation of the isoscalar giant monopole resonance (ISGMR) in $^{116}$Sn and $^{208}$Pb has been investigated using small-angle (including $0^\\circ$) inelastic scattering of 100 MeV/u deuteron and multipole-decomposition analysis (MDA). The extracted strength distributions agree well with those from inelastic scattering of 100 MeV/u $\\alpha$ particles. These measurements establish deuteron inelastic scattering at E$_d \\sim$ 100 MeV/u as a suitable probe for extraction of the ISGMR strength with MDA, making feasible the investigation of this resonance in radioactive isotopes in inverse kinematics.

D. Patel; U. Garg; M. Itoh; H. Akimune; G. P. A. Berg; M. Fujiwara; M. N. Harakeh; C. Iwamoto; T. Kawabata; K. Kawase; J. T. Matta; T. Murakami; A. Okamoto; T. Sako; K. W. Schlax; K. Takahashi; M. White; M. Yosoi
2014-06-26

297

Tool Support for Model Checking of Web Application Designs. http://www.elet.polimi.it/upload/mbrambil/webmlwave

  CiteSeer

Summary: Abstract: In this work we report our experience in applying model checking techniques to the analysis of static and dynamic properties of Web application models. We propose a mix of tools that facilitate model driven design of Web applications, automatic code generation, and automatic property verification. As recommended by current tendencies in the academic field, we bridge the gap between the tools by devising a set of MDA transformations between the different models. We show that such approach is feasible although we also highlight how current state-of-the-art industrial tools are still partially inadequate for providing seamless support to MDA approaches for industrial Web applications. 1.


2007-01-01

298

Sexual Compulsivity Among Men in a Decentralized MSM Community of the Midwestern United States

  University of Kansas - KU ScholarWorks

Summary: ), marijuana (pot), and crystal methamphetamine. Participants were asked to indicate whether or not they had used the drug in the past 90 days. Participants were also asked whether they had ever been told by a health care provider that they had a drug..., the most frequently reported substances in- cluded alcohol (57.7%, n #2; 291), marijuana (20.0%, n #2; 101), and inhalants such as poppers, snappers, or whippets (19%, n #2; 96). Men who scored higher on the SCS were more likely to use marijuana than men...

Satinsky, Sonya; Fisher, Christopher; Stupiansky, Nathan; Dodge, Brian; Alexander, Andreia; Herbenick, Debby; Reece, Michael
2008-01-01

299

Relating Kansas Offenses

  University of Kansas - KU ScholarWorks

Summary: on the ground that it was compelled by legal text. Even indulging the assumption that the term "compounding" has exactly the same meaning in the distribution and manufacture offenses, McAdam requires the additional premise that the punishment for identical... the culpability already inherent in the manufacture. Additional 59. 133 P.3d 48, 81 (Kan. 2006); cf State v. Patten, 122 P.3d 350, 355 (Kan. 2005) (holding that offenders may be convicted of both methamphetamine manufacture and possession of drug paraphernalia...

Stacy, Tom
2008-05-01

300

The Search for Medications to Treat Stimulant Dependence

  CiteSeer

Summary: Progress in understanding the neurobiology of stimulant dependence has enabled researchers to identify medications whose pharmacological effects suggest that they might help patients initiate abstinence or avoid relapse. Several of these medications and a vaccine have shown encouraging results in controlled clinical trials with cocaine-dependent patients. The search for a medical treatment for methamphetamine dependence started more recently, due to the later emergence of this epidemic, but at least one candidate medication has shown promise in early clinical testing. Treatment approaches that combine efficacious medications and empirically proven behavioral interventions, such as voucher-based reinforcement therapy, will almost certainly produce the best results.

Kyle M. Kampman

301

THESE DE DOCTORAT Trous Noirs Phant^omes

  Computer Technologies and Information Sciences Websites

Summary: with axial symmetry, for Einstein- anti-Maxwell-Dilaton (E ¯MD) and Einstein-anti-Maxwell-Dilaton-Axion (E-anti-Maxwell- Dilaton-`Axion (E ¯MDA). Analisamos as estruturas causais dessas novas solu¸c~oes. 3 tel-01023305,version1

Boyer, Edmond

302

ORIGINAL RESEARCH Open Access Syndecan-1 antigen, a promising new target for

  Physics Websites

Summary: ORIGINAL RESEARCH Open Access Syndecan-1 antigen, a promising new target for triple-negative breast cancer immuno-PET and radioimmunotherapy. A preclinical study on MDA-MB-468 xenograft tumors Caroline Research 2011, 1:20 http://www.ejnmmires.com/content/1/1/20 © 2011 Rousseau et al; licensee Springer

Paris-Sud XI, Université de

303

PHYSICAL REVIEW B 84, 014101 (2011) Polar distortions in hydrogen-bonded organic ferroelectrics

  Materials Science Websites

Summary: ferroelectric compounds containing hydrogen bonds were among the first to be discovered, organic ferroelectrics (CBDC) and 2-phenylmalondialdehyde (PhMDA). By using a distortion-mode analysis we shed light on the microscopic mechanisms contributing to the polarization, which we find to be as large as 14.3 and 7.0 C/cm2

Vanderbilt, David

304

Gray Code Enumeration of Families of Integer Partitions David Rasmussen \\Lambda

  Computer Technologies and Information Sciences Websites

Summary: Gray Code Enumeration of Families of Integer Partitions David Rasmussen \\Lambda Carla D. Savage y Research supported National Security Agency Grant No. MDA904­90­H­4011. 1 #12; Proposed Running Head: Gray change, or Gray code, order. In particular, we construct Gray code listings for the classes P ffi (n; k

Savage, Carla D.

305

Original article The protective effect of processed cheese

  Physics Websites

Summary: of fats on plasma lipid profile and lipid peroxidation using hypercholesterolemic rats as an experimental / lipid profile / conjugated linoleic acid ­ () ( 8 ) () 8 (Tg) (MDA matière grasse sur le profil lipidique du plasma et la peroxydation des lipides sur le rat

Paris-Sud XI, Université de

306

Expression of Wnt-signaling pathway proteins in intraductal papillary mucinous neoplasms of

  Biology and Medicine Websites

Summary: of the pancreas: a tissue microarray analysisB Runjan Chetty MB ChB, FRCPath, FRCPC, DPhila,*, Stefano Serra MDa. This pathway has not been explored in intraductal papillary mucinous neoplasms (IPMNs) of the pancreas). Keywords: Pancreas; Intraductal papillary mucinous neoplasm; Wnt signaling; b-catenin; APC; E

Woodgett, Jim

307

8th. World Congress on Computational Mechanics (WCCM8) 5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008)

  Mathematics Websites

Summary: EIGENSOLVERS FOR ANALYSIS OF MICROARRAY GENE EXPRESSION DATA * Andrew V. Knyazev1 1 Department of Mathematical://andrew.knyazev@cudenver.edu http://math.cudenver.edu/~aknyazev/ Key Words: Spectral Clustering, Eigenvalue Solvers, Microarray, Gene, Data Analysis. ABSTRACT Microarray data analysis (MDA) has become an important tool in molecular

Knyazev, Andrew

308

2014NatureAmerica,Inc.Allrightsreserved. brief communications

  Chemistry Websites

Summary: LysargiNase and trypsin digests of human breast cancer cells (line MDA-MB-231) using high and signaling6. Hence, new approaches are needed to overcome the problems in detecting C-terminal peptides detection of these epigenetic modifications. Proteomic identification of proteins and post

Cai, Long

309

10.1261/rna.1642809Access the most recent version at doi: 2009 15: 1338-1344 originally published online May 15, 2009RNA

  Biology and Medicine Websites

Summary: , University of Tuebingen, Tuebingen, Germany ABSTRACT The RNA ligase-containing or L-complex is the core complex involved in uridine insertion/deletion RNA editing in trypanosome mitochondria. Blue native gels-tagged editing protein, LC-8 (TbMP44/KREPB5), show a ;1 MDa L-complex band and, in addition, two minor higher

Simpson, Larry

310

EFFECT OF ULTRASOUND-ACTIVATED MICROBUBBLES ON THE CELL ELECTROPHYSIOLOGICAL PROPERTIES.

  Computer Technologies and Information Sciences Websites

Summary: and mammary breast cancer cell line MDA-MB-231 were used. Ultrasound was applied using single elementEFFECT OF ULTRASOUND-ACTIVATED MICROBUBBLES ON THE CELL ELECTROPHYSIOLOGICAL PROPERTIES. T.A. Tran1 title: Ultrasound, microbubble and cell interaction. Corresponding author: Ayache Bouakaz, PhD Inserm U

Boyer, Edmond

311

Simulating surface and subsurface initiation of macropore flow Markus Weilera,*, Felix Naefb,1

  Environmental Sciences and Ecology Websites

Summary: surface topography at four field sites with permanent grass vegetation with grid spacing of 10 cm into macropores based on different combinations of surveyed surface micro-topographies, spatial earthworm burrow topography and macropore density using a flow accumulation algorithm. The resulting MDA of each macropore

Weiler, Markus

312

Geophysical Fluid Dynamics Laboratory Review

  Environmental Sciences and Ecology Websites

Summary: air quality and climate via methane emission controls: A viable option? North America Ozone reduction where surface ozone (MDA8) > 70 ppbv CLIMATE AIR QUALITY 2) pp BASE 2005 BASE 2030 CH4 OZONE METHANE (W of Future Changes in Climate on Air Quality 20year AM3 simulations with annuallyinvariant emissions of ozone


313

RESEARCH ARTICLE Open Access Stimulation of angiogenesis resulting from

  Engineering Websites

Summary: macrophages and MDA- MB-231 breast cancer cells: proposed molecular mechanism and effect of tetrathiomolybdate , Claudine Soria1 Abstract Background: Infiltration by macrophages (M) indicates a poor prognosis in breast is due to the capacity of M to switch from M1 M towards M2, probably due to an increase in Macrophage


314

Invasive Species: Lightning Round!

  Energy Storage, Conversion and Utilization Websites

Summary: ://www.mda.state.mn.us/plants/pestmanagement/eab.aspx · Maryland Avenue Bridge Project · 694/Snelling Project #12;Treatment OpCons � Heat should be aware of designated infested waters in their area. hCp://files.dnr.state.mn.us/eco/invasives/infested_waters ­ DEAD or ALIVE ! #12;DNR permits are not valid for work in waters

Minnesota, University of

315

Metric Diophantine Approximation for Formal Laurent Series over Finite Fields

  Mathematics Websites

Summary: Metric Diophantine Approximation for Formal Laurent Series over Finite Fields Michael Fuchs Department of Applied Mathematics National Chiao Tung University Hsinchu, Taiwan Fq9, July 16th, 2009 Michael) probability measure. Michael Fuchs (NCTU) MDA in positive characteristic Fq9, July 16th, 2009 2 / 20 #12

Fuchs, Michael

316

RAMSEY THEORY AND BANDWIDTH OF GRAPHS Zoltan Furedi

  Mathematics Websites

Summary: Security Agency under grant MDA904-98-I-0022. Running head: BANDWIDTH SUM AMS codes: 05C35, 05C78, 05C80) is the smallest integer n such that every red/blue-coloring of the edges of Kn yields a copy of A in red or a copy of B in blue. When n

Furedi, Zoltan

317

SoSyM manuscript No. (will be inserted by the editor)

  Computer Technologies and Information Sciences Websites

Summary: UML to Alloy Kyriakos Anastasakis1 , Behzad Bordbar1 , Geri Georg2 , Indrakshi Ray2 1 School. Specifically, we show how UML models can be automatically transformed into Alloy which, in turn, can be automatically analysed by the Alloy Ana- lyzer. The proposed approach relies on MDA techniques to transform UML

Ray, Indrakshi

318

SoSyM manuscript No. (will be inserted by the editor)

  Computer Technologies and Information Sciences Websites

Summary: UML to Alloy Kyriakos Anastasakis1 , Behzad Bordbar1 , Geri Georg2 , Indrakshi Ray2 1 School be automatically transformed into Alloy which, in turn, can be automatically analysed by the Alloy Analyzer. The proposed approach relies on MDA techniques to transform UML models to Alloy. This paper reports

Bordbar, Behzad

319

NUMERICAL SOLUTION OF POSITIVE SUM EXPONENTIAL EQUATIONS

  Mathematics Websites

Summary: Grant MDA904­85­4009 and NASA Grant NAG2­82. c #2003 Texas Tech University 1 #12; 2 C. Martin, J. Miller , · · · , c n are positive. This assumption is standard in the literature and, for many of the applications) with initial condition x(0) = a; the solution is then continued from t = 0 to t = 1. In order for this method

Pearce, Kent

320

Abordagem XIS ao Desenvolvimento de Sistemas de Informao Alberto Rodrigues da Silva

  Computer Technologies and Information Sciences Websites

Summary: , designadamente: segue uma abordagem baseada na especificação de modelos; centrada em arquitecturas de software; e interactivos, MDA, modelos em UML e XML, geração automática, arquitecturas de software 1 Introdução responsáveis por providenciar arquitecturas elegantes, flexíveis e reutilizáveis. A ideia subjacente ao

da Silva, Alberto Rodrigues

321

DOBLE GRADO MATEMTICAS + INGENIERA DEL SOFTWARE Coordinador Titulacin: Paloma Cceres (paloma.caceres@urjc.es)

  Mathematics Websites

Summary: Informática GIS (III, 004) IP Introducción a la Programación GIS (III, 004) LOG Lógica GIS (III, 004) MDA Matemática Discreta y Álgebra MAT (III, 002) EA Estructuras Algebraicas MAT (III, 001) EST Estadística GIS) Claves y profesores Clave Asignatura Profesor CAL Cálculo MAT (III,002) ED Estructura de datos GIS (III

Rey Juan Carlos, Universidad

322

DOBLE GRADO INGENIERA INFORMTICA -INGENIERA DEL SOFTWARE Coordinador Titulacin: Paloma Cceres (paloma.caceres@urjc.es)

  Engineering Websites

Summary: Físicos de la Informática GIS (III, 004) IP Introducción a la Programación GIS (III, 004) LOG Lógica GIS (III, 004) MDA Matemática Discreta y Álgebra GIS (III, 004) EST Estadística GIS (III, 004) L M X J V 9 Claves y profesores Clave Asignatura Profesor CAL Cálculo GIS (III, 004) ED Estructura de datos GIS (III

Rey Juan Carlos, Universidad

323

Final Report on Research in Parallel Computing: Networkbased Multicomputers

  Computer Technologies and Information Sciences Websites

Summary: 1995 Carnegie Mellon University Computer Science Department Abstract No existing parallel architecture, and monitored by the Space and Naval Warfare Systems Command under contract MDA972­90­C­0035. Views architectures, such as SIMD machines, MIMD machines, vector processors, machines with a common (globally


324

Hardware Accelerated Algorithms for Semantic Processing of Document Streams

  Computer Technologies and Information Sciences Websites

Summary: by the Air Force Research Laboratory, Air Force Materiel Command, USAF, under Contract number MDA972 Research, Inc. 600 South Washington Suite 100 Naperville, IL 60540 eick@sss- research.com John W. Lockwood ................................................13 12. BIOGRAPHIES ...............................................13 1 This research was sponsored

Lockwood, John W.

325

AD : Airworthiness Directive ADC : Air Data Computer

  Multidisciplinary Databases and Resources Websites

Summary: : Standard Operating Procedure SPD : Speed SPD/MAC : Speed/Mach SRS : Speed Reference System SW : Switch TCC Digital Electronic Control FCC : Flight Control Computer FCOM : Flight Crew Operating Manual FCU : Flight Aerodynamic Chord MAN THR : Manual Thrust MDA : Minimum Decision Altitude MIC : Microphone MTP : Maintenance

Ladkin, Peter B.

326

PM till slutseminarium den 20 mars 2013 Institutionen fr arkeologi och antikens kultur, Stockholms universitet

  Environmental Sciences and Ecology Websites

Summary: om termen använts flitigt som metafor för ett delat Europa fanns det också en serie hårt militariserade gränser som löpte genom Europa. I min forskning har jag tagit Churchills berömda beskrivning av


327

Available Units of Study Commencement 2007 Onwards

  Physics Websites

Summary: of the Following): PHI10002 (HAH100) Introduction to Philosophy Nil Paul Healy 5405 PHI10003 (HAH103) Critical Thinking Nil Paul Healy 5405 POL10001 (HAP100) Australian Politics Nil Peter Love 8038 SOC10004 (HAS111 Communication Practice) Nil Mark Finn 5254 MDA10004 (HAM105) The Media in Australia Nil Anthony McCosker 4984

Liley, David

328

Detection of Covalent and Noncovalent Intermediates in the Polymerization Reaction Catalyzed by a C149S Class III Polyhydroxybutyrate Synthase

  MIT - DSpace

Summary: Polyhydroxybutyrate (PHB) synthases catalyze the conversion of 3-hydroxybutyryl coenzyme A (HBCoA) to PHB with a molecular mass of 1.5 MDa. The class III synthase from Allochromatium vinosum is a tetramer of PhaEPhaC (each ...

Li, Ping

329

Published: September 01, 2011 r 2011 American Chemical Society 2252 dx.doi.org/10.1021/mp200346y |Mol. Pharmaceutics 2011, 8, 22522261

  Materials Science Websites

Summary: That Inhibits the HOPÃ?Hsp90 Complex Formation and Has Unique Killing Effects in Breast Cancer Cell Lines Genaro- tive breast cancer (TNBC) cell line MDA-MB-231. We have also extended the investigation of the most range of different cancer types.7 The natural product geldanamycin and its derivatives such as 17-AAG

Mochrie, Simon

330

[CANCER RESEARCH 63, 71587166, November 1, 2003] The Gene Expression Response of Breast Cancer to Growth Regulators: Patterns

  Biotechnology Websites

Summary: [CANCER RESEARCH 63, 7158­7166, November 1, 2003] The Gene Expression Response of Breast Cancer transcriptional effects elicited in MCF7, T-47D, and MDA-MB-436 breast cancer cell lines by nine regulators at the gene expression level of diverse regulators of breast cancer growth and links the behavior of breast

Ringnér, Markus

331

Published in: International Journal of Cancer (2006), vol. 118, iss.1, pp. 35-42 Status: Postprint (Author's version)

  Physics Websites

Summary: (Author's version) Transactivation of MCP-1/CCL2 by -catenin/TCF-4 in human breast cancer cells Melanie. Indeed, MCP-1 was expressed by invasive breast cancer cells (MDA- MB-231, BT549 and Hs578T), which do not express E-cadherin but was not produced by noninvasive breast cancer cell lines (MCF7 and T47D) expressing

Paris-Sud XI, Université de

332

Fat Points, Inverse Systems, and Piecewise Polynomial Anthony V. Geramita

  Mathematics Websites

Summary: Fat Points, Inverse Systems, and Piecewise Polynomial Functions Anthony V. Geramita and Hal Schenck Abstract We explore the connection between ideals of fat points (which correspond to sub- schemes of Pn Partially supported by the National Security Agency through grant MDA 904-95-H-1035 1 #12;Fat Points

Schenck, Hal

333

Carleton University, TR SCE-06-08 March 2006 A Metamodeling Approach to Pattern Specification

  Computer Technologies and Information Sciences Websites

Summary: specification process. It also contains features to manage the complexity of specifying patterns and simplify-of-the-art technolo- gies that are heavily used by major modeling tool vendors, thus facilitating its adoption on technology investment, the adoption of MDA has not picked up to its full potential yet. One reason

Briand, Lionel C.

334

(IJCSIS) International Journal of Computer Science and Information Security, Vol. 11, No. 6, June 2013

  Physics Websites

Summary: --The sustainability of any Data Warehouse System (DWS) is closely correlated with user satisfaction. Therefore. Then we present our approach inspired from the MDA (Model Driven Architecture) approach to model their interaction. Keywords-component; Data Warehouse System; Model Driven Architecture ; Dependability

Paris-Sud XI, Université de

335

GALOIS MODULE STRUCTURE OF MILNOR K-THEORY IN CHARACTERISTIC p

  Mathematics Websites

Summary: GALOIS MODULE STRUCTURE OF MILNOR K-THEORY IN CHARACTERISTIC p GANESH BHANDARI, NICOLE LEMIRE , J supported in part by NSA grant MDA904-02-1-0061. 1 #12;2 BHANDARI, LEMIRE, MIN´AC, AND SWALLOW The precise


336

GALOIS MODULE STRUCTURE OF MILNOR KTHEORY IN CHARACTERISTIC p

  Mathematics Websites

Summary: GALOIS MODULE STRUCTURE OF MILNOR K­THEORY IN CHARACTERISTIC p GANESH BHANDARI, NICOLE LEMIRE # , J supported in part by NSA grant MDA904­02­1­0061. 1 #12; 2 BHANDARI, LEMIRE, MIN â?? A Ÿ C, AND SWALLOW


337

Trip report to Stockholm, Sweden, 1-3 September 2008 Background. Sweden has a rich tradition of military and technological (for instance, one

  Biotechnology Websites

Summary: Trip report to Stockholm, Sweden, 1-3 September 2008 Background. Sweden has a rich tradition and execution of peacekeeping and other non classified operations (indeed, Sweden has troops in Afghanistan and The Congo today; they lead the Baltic MDA effort). Sweden's relatively small size makes them forward leaning


338

Mehmet Aksit Ekkart Kindler

  Engineering Websites

Summary: Proceedings Series WP09-04 ISSN 0929-0672 #12;#12;Organisation Organizing Committee Mehmet Aksit. TU Twente generation of behavioral code ­ too ambitious or even unwanted? G. Engels University of Paderborn, Germany of Latvia 3. Composition Semantics for Executable and Evolvable Behavioral Modeling in MDA

Al Hanbali, Ahmad

339

Asthma,rhinitis,other respiratorydiseases

  Biology and Medicine Websites

Summary: Asthma,rhinitis,other respiratorydiseases 415 Rhinitis therapy and the prevention of hospital care for asthma: A case-control study Jonathan Corren, MD,a Beatrice E. Manning, PhD,b Stephen F. Thompson, MS therapy improves subjective and objective measures of asthma, it is uncertain whether treatment

Hennessy, Sean

340

Induction of Oxidative Stress by Sunflower Phytotoxins in Germinating Mustard Seeds

  Biology and Medicine Websites

Summary: Induction of Oxidative Stress by Sunflower Phytotoxins in Germinating Mustard Seeds Krystyna Oracz the phytotoxic effect of sunflower on physiological and biochemical processes during germination of mustard seeds germination, but only phytotoxins caused an increase in the cell membrane permeability, MDA level, H2O2

Leubner, Gerhard

341

If a student does not have a co-major it is recommended they take: STA30001 (LSQ331) Applied Statistics project or BUS30008 (LZZ331) Work Integrated Learning Project.

  Physics Websites

Summary: Statistics project or BUS30008 (LZZ331) Work Integrated Learning Project. MEDIA STUDIES PROFESSIONAL MAJOR NB) Nil STA10003 (LCR102) Foundations of Statistics Nil SOC10007 (HAS120) Understanding the Modern World Media Crime & Policy (replaced LSM305 Australian Media Policy) Nil MDA30001 (LSM308) Media, Advertising

Liley, David

342

1 Swinburne University of Technology | CRICOS Provider 00111D | swinburne.edu.au Media Studies Co-major

  Physics Websites

Summary: Media Crime and Policy (replaces LSM305 Australian Media Policy) MDA30001 Media, Advertising, Sport for the correct 2014 unit code. Minors Applied Statistics Advanced Minor (for Psychology Students only) Students) STA20004 Sport Statistics (formerly HMA281) ** STA20009 Introduction to Epidemiology (formerly HMS240

Liley, David

343

NJIT RESEARCHERS ARE PUTTING A 2 1ST CENTURY SPIN ON A 1 9TH CENTURY technology to make the nation's ports and coastal waters safer. Airships --known today

  Computer Technologies and Information Sciences Websites

Summary: 's ports and coastal waters safer. Airships -- known today mainly for advertising flyovers at football Agency (MDA) of the U.S. Department of Defense. But the new models will bear little resemblance that allows us to respond quickly to an emerging need such as homeland security." While the airship technology

Bieber, Michael

344

Asymptotic Analysis of Multivariate Coherent Risks lih@math.wsu.edu

  Mathematics Websites

Summary: Asymptotic Analysis of Multivariate Coherent Risks Haijun Li lih@math.wsu.edu Washington State Asymptotic Analysis of Multivariate Coherent Risks 7th MDA, 08/10/2010 1 / 22 #12;Outline 1 Coherent Risks Asymptotic Analysis of Tail Conditional Expectations Multivariate Regular Variation Tail Risk of Multivariate

Li, Haijun

345

A Document Model Management Framework based on Core Components

  Computer Technologies and Information Sciences Websites

Summary: of electronic documents is one of the most important aims in today's busi- nesses. At the same time the need for a consistent framework for the management of electronic business documents, together with tool support rises IT systems. Also, such MDA related tools are currently rare in the domain of business document engineering


346

Model-Driven Service Level Management Anacleto Correia1,2

  Computer Technologies and Information Sciences Websites

Summary: : IT Service Management, ITIL; Service Level Management; Service Level Agreements, Metamodels, MDA; Domain an IT Service Management (ITSM) framework. Several ITSM frameworks have been proposed, such as the ITIL [1]. In ITIL, one of the most relevant processes is service level management [2]. In order to support

Boyer, Edmond

347

Evaluating ecological tradeoffs in fisheries management: a study case for the yellowfin tuna fishery in the Eastern Pacific Ocean

  Environmental Sciences and Ecology Websites

Summary: in the selection of alternative policy options. An important class of techniques within MDA is vector optimization perspective, vector optimization models are particularly suited for situations when the decision rule requires, a Convention for the establishment of the Inter-American Tropical Tuna Commission (IATTC) was signed

Enríquez Andrade, Roberto Ramón

348

www.agbioresearch.anr.msu.edu Northern Michigan FruitNet 2013

  Renewable Energy Websites

Summary: , growers must also sign the MDA training affidavit athttp://www.michigan.gov/mdard/0,4610,7-125-1568_2390_45088-275564-- ,00.html. This process is straight forward, and the signed affidavit must be kept with the special that were planted this spring, there are a few open blooms on these trees and they may need to be protected


349

Transcranial direct current stimulation: State of the art 2008

  Biology and Medicine Websites

Summary: Transcranial direct current stimulation: State of the art 2008 Michael A. Nitsche, MDa , Leonardo G. Beyond this, transcranial direct current stimulation (tDCS) of different cortical areas has been shown direct currents is a promising tool in human neuroscience and neurobehavioral research. To facilitate

Miall, Chris

350

L034 Bachelor of Professional Communication Program Planner

  Computer Technologies and Information Sciences Websites

Summary: by Digital Communities 1 Nil Professional Major LSM308 MDA30001 Media, Advertising, Sport and Society 2 Nil100 or LPR100 Professional Major LCA100 ADV10001 Principles of Advertising 1 or 2 Nil Professional20001 Advertising Issues: Regulations, Ethics & Cultural Considerations 2 LCA100 Professional Major LCA

Liley, David

351

Commencing 2007 onwards Bachelor of Health Science (Public Environmental Health) -Course H069

  Computer Technologies and Information Sciences Websites

Summary: Commencing 2007 onwards Bachelor of Health Science (Public Environmental Health) - Course H069 Dean Lusher 8687 CHE10004 (HES1490) Introduction to Chemistry Nil Daniel Eldgridge 5681 BIO10001 (HES and Environmental Health Nil Louise Dunn 8770 Sem 2 LAW10001 (HBSL100) Introductory Law Nil Silvana Wilson 5288 MDA

Liley, David

352

Meet the ALS Clinic Team Dr. Amy Gutierrez, MD FAAN Neurologist completed her residency and fellowship at LSU

  Biology and Medicine Websites

Summary: ) or email anna@accessrespiratory.com. Maria Kay, Physical Therapist, graduated from the LSU Medical Center. Maria can be reached by email at mkaypt@aol.com. Melanie Lepine, Social Worker has over fifteen years Dystrophy Association, has worked with MDA since 2011. She has a Bachelor's of Science in Family and Child


353

Dehydroepiandrosterone Improves Hepatic Antioxidant Systems after Renal Ischemia-Reperfusion Injury in Rabbits

  CiteSeer

Summary: Abstract. This study evaluated the effects of dehydroepiandrosterone (DHEA) on the oxidant [malondialdehyde (MDA)] and antioxidant [superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), and glutathione (GSH)] systems in liver after renal ischemia-reperfusion (IR) injury in rabbits. Thirty rabbits were randomly assigned to 3 groups of 10: group I (sham operation), group II (renal IR group), and group III (DHEA, 25 mg/kg, sc, 15 min pre-ischemia). Renal IR injury in group II caused a decrease of SOD (25 %), GPx (36 %), and CAT (26 %) activities and GSH levels (32 %), and increases of MDA (30 %) in liver and of ALT and AST activities in serum, compared to group I. DHEA administration decreased the hepatic MDA level (19 %) and serum ALT activity (30 %) (p <0.01 and p <0.05, respectively), and considerably increased hepatic GSH levels and GPx activities (p <0.01 for both) in group III, compared to group II. These results suggest that DHEA treatment has beneficial effects on antioxidant defenses against hepatic injury after renal IR in rabbits, possibly by augmenting GSH levels and lowering MDA

Abdulkadir Yildirim; Metehan Gumus; Sebahattin Dalga; Y. Nuri Sahin; Fatih Akcay
2003-01-01

354

Mitigation of Network Tampering Using Dynamic Dispatch of Mobile Agents

  Computer Technologies and Information Sciences Websites

Summary: or hooks installed by the attacker to facilitate subsequent access. Over the past 20 years, numerous revenge by a distraught system administrator who malevolently alters enterprise-critical executables. Supported in-part by National Security Agency MDA904-99-C-2642 subcontract and a Lucent Florida Universities

DeMara, Ronald F.

355

J5.2 A Neural Network for Detecting and Diagnosing Tornadic Circulations using the Mesocyclone Detection and Near Storm

  Geosciences Websites

Summary: J5.2 A Neural Network for Detecting and Diagnosing Tornadic Circulations using the Mesocyclone, these circulations are precursors to tornadoes. Marzban and Stumpf (1996) developed a neural network based on the MDA further extend the work to use 83 storm days and introduce some variations that improve neural network

Lakshmanan, Valliappa

356

Histochem Cell Biol (2005) 123:89104 DOI 10.1007/s00418-004-0722-9

  Environmental Sciences and Ecology Websites

Summary: neuron clusters (MNv-1), gastrodermal cells (MDa-1) and spermatids (MSp-1). Confocal microscopy · Differentiation · Stem cells · Neoblasts · Turbellaria Introduction During embryogenesis cells become determined nervous system, an blind-ending gut and a remark- able stem cell system. Within the animal kingdom

Schärer, Lukas

357

CONSTRUCTIVE RECOGNITION OF SL 3 (q) UBECK, K. MAGAARD, AND E.A. O'BRIEN

  Mathematics Websites

Summary: CONSTRUCTIVE RECOGNITION OF SL 3 (q) F. L  UBECK, K. MAGAARD, AND E.A. O'BRIEN Abstract. We- ested reader to O'Brien [20] for background related to this work, and to Carter [7] for concepts related grant MDA-9049810020. O'Brien was partially supported by the Marsden Fund of New Zealand via grant UOA

Lübeck, Frank

358

CONSTRUCTIVE RECOGNITION OF SL3(q) F. LUBECK, K. MAGAARD, AND E.A. O'BRIEN

  Mathematics Websites

Summary: CONSTRUCTIVE RECOGNITION OF SL3(q) F. L¨UBECK, K. MAGAARD, AND E.A. O'BRIEN Abstract. We present of subgroups of GLd(Fq) where Fq is a finite field of size q = pe . We refer the inter- ested reader to O'Brien recognition. Magaard was partially supported by NSA grant MDA-9049810020. O'Brien was partially supported

Lübeck, Frank

359

CONSTRUCTIVE RECOGNITION OF SL 3(q) F. L"UBECK, K. MAGAARD, AND E.A. O'BRIEN

  Mathematics Websites

Summary: CONSTRUCTIVE RECOGNITION OF SL 3(q) F. L"UBECK, K. MAGAARD, AND E.A. O'BRIEN = pe. We refer the inter- ested reader to O'Brien [20] for background related to this work. Magaard was partially supported by NSA grant MDA-9049810020. O'Brien was partially supported

Lübeck, Frank

360

Yale Pediatrics A PRACTICE OF THE YALE MEDICAL GROUP PEDIATRIC SPECIALTY NEW PATIENT FORM Date

  Materials Science Websites

Summary: -737-7635 Nephrology 203-737-7635 Type 1 Diabetes 203-764-6748 Endocrinology 203-737-7635 Neurology 203-737-7635 Type 2/Behavioral Pediatrics Rheumatology Endocrinology Spina Bifida GI Thyroid Center MDA/Neuromuscular Type 2 Diabetes (203-785-4081 #1), we will fax form to you for confirmation. 1 PHONE OPTION/APPOINTMENT CONFIRMATION


361

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, VOL. 53, NO. 5, MAY 2006 941 A Control Algorithm for Autonomous Optimization

  Biology and Medicine Websites

Summary: by the National Science Foundation (NSF) under Grant 9402726 and in part by the Defense Advanced Research Projects Agency (DARPA) under Grant MDA972-00-1-0029. Asterisk indicates corresponding author. *Z. Nenadic are introduced in neural tissue for a period of several hours. During these experiments, op- erators advance high

Nenadic, Zoran

362

Bankruptcy Prediction Using Feature Projection Based Classification

  Computer Technologies and Information Sciences Websites

Summary: Ankara 06533, Turkey And Erdal Erel Management Department, Bilkent University Ankara 06533, Turkey assets, cash / total sales, net in­ come / total assets, and (total assets ­ inven­ tories) / total liabilities. In MDA a discrim­ inant function of such financial ratios is con­ structed. If the value

Güvenir, H. Altay

363

Tellus (2007), 59A, 444454 C 2007 The Authors Journal compilation C 2007 Blackwell Munksgaard

  Geosciences Websites

Summary: storm and hurricane) frequency from year to year. Large-scale environmental conditions during the peak hurricane season (July, August and September) are contrasted for two extreme years; 1992 is the most active changes over the major development area (MDA) for the two extreme years. For instance, the 1992 hurricane

Hawai'i at Manoa, University of

364

What makes a good microtubule nucleator? ?-Tubulin is only half the story.

  CiteSeer

Summary: ?-Tubulin nucleates microtubules (MTs) in all eukaryotes and acts in complex with an array of related accessory proteins. It exists in at least two types of complexes inside cells: a ~300kDa ?-Tubulin Small Complex (?TuSC), which can assemble to form a ~2.2MDa ?-Tubulin Ring Complex (?TuRC). In

Microtubule Cytoskeleton; M. Moritz; J. Kollman; D. A. Agard Biochemistry; San Francisco

365

RAMANUJAN AND CRANKS BRUCE C. BERNDT 1 , HENG HUAT CHAN, SONG HENG CHAN, AND WEN--CHIN LIAW

  Mathematics Websites

Summary: RAMANUJAN AND CRANKS BRUCE C. BERNDT 1 , HENG HUAT CHAN, SONG HENG CHAN, AND WEN--CHIN LIAW by grant MDA904­00­1­0015 from the National Security Agency. 1 #12; 2 B. C. BERNDT, H. H. CHAN, S. H. CHAN

Berndt, Bruce C.

366

Correspondence homomorphisms for singular varieties Eric M. Friedlander #,+ and Barry Mazur #

  Mathematics Websites

Summary: filtrations on the homology of projective varietes. We show that a natural refinement #f a refinement � # f : H # (Y ) # # Partially supported by the N.S.F. and + NSA Grant # MDA904­90­H­4006 1 #12; H as follows. In section 1, we construct the correspondence homo­ morphism # f and its refinement #f


367

NW Michigan Regional Fruit Grower Newsletter November 2005

  Renewable Energy Websites

Summary: Certification Review & Test NWMHRS 12/12 Pesticide Certification Review & Test Banks Township Hall, Ellsworth 12 & TEST SESSIONS Nikki Rothwell, District Fruit IPM Educator Duke Elsner, Agricultural Agent, Grand on your own 1:00 to 3:00 p.m. Certification Tests offered by MDA There is no cost for either review


368

The Journal of Neuroscience, August 1995, 75(8): 5448-5465 An Emergent Model of Orientation Selectivity in Cat Visual Cortical

  Biology and Medicine Websites

Summary: Performance Computing time from the Project Scout at MIT-LCS, spon- sored under ARPA Contract MDA 972-92-JDonnell-Pew Center for Cognitive Neuro- science at MIT, NIH Grants MH-10671, EY-06363, EY-07023; and a grant of High

Somers, David

369

SEPARABILITY, MULTI-VALUED OPERATORS, AND ZEROES OF L-FUNCTIONS

  Mathematics Websites

Summary: SEPARABILITY, MULTI-VALUED OPERATORS, AND ZEROES OF L-FUNCTIONS DAVID GOSS Abstract. Let k was supported by NSA grant MDA 904-97-1-0048. 1 #12;2 DAVID GOSS operators. In the paper we will denote the copy


370

Strata: A Multi-Layer Communications Library Version 2.0 Beta

  Computer Technologies and Information Sciences Websites

Summary: Laboratory for Computer Science February 15, 1994 Strata is a multi-layer communications library under is supported by Project SCOUT (ARPA Contract MDA972-92-J-1032); by the National Science Foundation, grant CCR Time Primitive Time CMMD_sync_with_nodes 170 cycles Barrier 140 cycles CMMD_scan_int 380 cycles Combine

Leiserson, Charles E.

371

Market Wire: Western Reports First Quarter 2008, Results Reflect Forest Products Market Downturn FindArticles > Market Wire > May, 2008 > Article > Print friendly

  Renewable Energy Websites

Summary: reports and comments on the financial condition and results of operations of Western Forest Products Inc underlying our financial results. This discussion and analysis should be read in conjunction with our audited annual consolidated financial statements and management's discussion and analysis ("MD&A") for the year


372

Administrivia Objectives Outline Engineering 9874

  Computer Technologies and Information Sciences Websites

Summary: . Object-Oriented Software Engineering: Using UML, Patterns, and Java. Pearson Prentice Hall, second edition, 2004. [2] Robert C. Martin. Agile Software Development: Principles, Patterns, and Practices Ready for MDA. Addison-Wesley, second edition, 2003. #12;Administrivia Objectives Outline Other

Peters, Dennis

373

2010NatureAmerica,Inc.Allrightsreserved. Nature GeNetics ADVANCE ONLINE PUBLICATION

  Environmental Sciences and Ecology Websites

Summary: s Complex I of the mitochondrial respiratory chain is a large ~1-MDa macromolecular machine composed of 45 entry point to the respiratory chain and catalyzes the transfer of electrons from NADH to ubiquinone are the most common type of human respiratory chain disease, which collectively has an incidence of 1 in 5


374

Matematik Dnyas>, 2005 K>fl ahit Arf'> tan>ma mutluluuna erdim. ok

  Mathematics Websites

Summary: ¤in tan>m> akl>mda kal- m>fl. Önemli bir fley söyleyece¤inin ayr>m>nda olan insanlar>n tavr>yla bana do>dvan Naf>z Bey, bu idealist tavr> için Cahit'i kutlamakla birlikte, bu konuda isabetli düflünmedi¤i- ne onu

Sertöz, Ali Sinan

375

10092 DOI: 10.1021/la901109e Langmuir 2009, 25(17), 1009210099Published on Web 07/07/2009 pubs.acs.org/Langmuir

  Materials Science Websites

Summary: .acs.org/Langmuir © 2009 American Chemical Society Cadherin and Integrin Regulation of Epithelial Cell Migration Jonathan on the integrin- mediated motility of epithelial cells. Micropatterned proteins were used to quantitatively on the migration velocities of MDA- MB-231 breast tumor epithelial cells. Fibronectin, E-cadherin, and mixtures

Kenis, Paul J. A.

376

GENERATION OF UML USE CASES FROM MEASUR ONTOLOGY CHARTS

  Computer Technologies and Information Sciences Websites

Summary: GENERATION OF UML USE CASES FROM MEASUR ONTOLOGY CHARTS AN MDA APPROACH D R . G E O R G E T S A R interaction with the system from an ontology chart? Significance: Simplified, easy to understand view > [Condition] #12;WHAT IS A MEASUR'S ONTOLOGY CHART #12;TYPES OF AFFORDANCES #12;ONTOLOGY CHART

Lano, Kevin Charles

377

Carthusian snail Monacha cartusiana Michigan State University's invasive species factsheets

  Renewable Energy Websites

Summary: as a prohibited mollusk species by Michigan's plant protection regulations (MDA 2009). Plant hosts A wide variety shell up to 15 mm in diameter; 5.5 to 6 whorls; shell white to pale brown in color, somewhat solid without regard to race, color, national origin, gender, gender identity, religion, age, height, weight


378

Whole genome amplification of the rust Puccinia striiformis f. sp. tritici from single spores

  Renewable Energy Websites

Summary: 2009 Keywords: -tubulin gene Multiple displacement amplification rDNA-ITS Single-spore Whole genome for DNA extractions. Multiple displacement amplification (MDA) was demonstrated in this study for whole genome amplification from single spores of the rust fungus, Puccinia striiformis. The genomic DNA

Hsiang, Tom

379

FROM SEQUENCE DIAGRAMS UML 2.x TO FD-DEVS BY MODEL TRANSFORMATION

  Physics Websites

Summary: FROM SEQUENCE DIAGRAMS UML 2.x TO FD-DEVS BY MODEL TRANSFORMATION Roberto Pasqua1,2 Damien Foures1,dfoures,valbert,alex}@laas.fr KEYWORDS MDA, meta-modeling, Sequence Diagrams, Finite and Deterministic DEVS, discrete event simulation ABSTRACT This work transforms sequence diagrams to Finite and Deterministic DEVS (FD-DEVS) in Model

Paris-Sud XI, Université de

380

Designed especially for college-bound high school students, the Summer Scholar Program at UC Irvine provides outstanding high school students

  Biology and Medicine Websites

Summary: and unique demands of a college career, and explore the unlimited potential that you possess. In addition: Performance Now (Tu /Th 1:00PM ­ 3:50PM) FLM&MDA 85A: Introduction to Film Analysis (TimeTBD) MUSIC 14C

Rose, Michael R.

381

Updated 6-13 Senior Director for Security

  Materials Science Websites

Summary: ) in Suitland, Maryland. Her last position while at ONI was as the Assistant Director of Global Maritime Awareness (MDA) information system, which was designed to provide real-time, operationally-focused maritime until September 2007, Mr. Kay served in a variety of positions at the Office of Naval Intelligence (ONI


382

Arrangement of electron transport chain components in bovine mitochondrial

  Chemistry Websites

Summary: the proton gradient for ATP synthesis, and assemble into a supercomplex. A 19-A° 3D map of the 1.7-MDa¨gger and Pfeiffer, 2000). A first 3D ma Abteilung Strukturbiologie, Max-Planck-Institut fu¨r Biophysik, Frankfurt, Germany and 2 Institut de


383

A comparative study of nano-scale coatings on gold electrodes for bioimpedance studies of breast cancer cells

  Materials Science Websites

Summary: - sitivity to MDA-MB-231 metastatic breast cancer cells. There was also a significant shift in the peak roughness . Bioimpedance . ECIS . Breast cancer 1 Introduction Bioimpedance is the complex electricalA comparative study of nano-scale coatings on gold electrodes for bioimpedance studies of breast

Heflin, Randy

384

Page 1 of 8 POULTRY HEALTH REQUIREMENTS FOR ADMISSION TO

  Biology and Medicine Websites

Summary: @mda.state.md.us 1. What are the regulations on Avian Influenza testing? · Poultry must come from flocks if less than 30, must test negative for H5/H7 low pathogenic AI. These flocks may register as a U.S. NPIP untested poultry to the flock negates NPIP AI clean status. · Otherwise, all poultry shown must test

Hamza, Iqbal

385

A N U A R I O C I N V E S T A V780 DEPARTAMENTO DE ECOLOGA HUMANA

  Mathematics Websites

Summary: características del crecimiento y desarrollo humanos, y el comportamiento y las condiciones de salud, fisiológicas (Neu- rociencias del Comportamiento, 1994) Universidad de Boston, EUA. Temas de investigación: Salud información geográfica en salud. lola@mda.cinvestav.mx HERIBERTO EMILIO CUANALO DE LA CERDA Investigador


386

Structural Basis of Viral RNA Recognition by RIG-I-Like Receptors

  Texas A&M University - TxSpace

Summary: RIG-I-like receptors (RLRs), RIG-I, MDA5, and LGP2, are a family of innate immune receptors that recognize viral RNA in the cytoplasm and initiate antiviral responses including the induction of type I interferons and other pro-inflammatory cytokines...

Lu, Cheng
2012-10-19

387

CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

  University of Cambridge - Dspace

Summary: and tissue microarrays. By flow cytometry, we characterized CD146 expression on different breast cancer cell lines. Using siRNA or shRNA technology, we studied functional consequences of CD146 downmodulation of MDA-MB-231 cells in migration assays. Wild...

Zabouo, Gwladys; Imbert, Anne-Marie; Jacquemier, Jocelyne; Finetti, Pascal; Moreau, Thomas; Esterni, Benjamin; Birnbaum, Daniel; Bertucci, Francois; Chabannon, Christian
2009-01-05

388

PERCOLATION, FIRST-PASSAGE PERCOLATION, AND COVERING TIMES FOR RICHARDSON'S MODEL ON

  Mathematics Websites

Summary: by the National Security Agency under Grant Number MDA904-89-H-2051. 2 Research supported by a National Science by percolation theory. "Suppose we immerse a large porous stone in water. What is the probability that the centre elements may be connected by a channel broad enough to allow the flow of water, or they may not be. Model

Pemantle, Robin

389

Genes and Immunity (2000) 1, 358361 2000 Macmillan Publishers Ltd All rights reserved 1466-4879/00 $15.00

  Biology and Medicine Websites

Summary: Manni1 , LG Kostrikis2 and AU Neumann4 1 Hadassah Hospital, Jerusalem 91000, Israel; 2 The Aaron Diamond AIDS Research Center, New York, NY 10016, USA; 3 MDA ­ Israel National Blood Services, Ramat-Gan, Israel; 4 Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel Recent studies have


2000-01-01

390

Applied and Computational Harmonic Analysis 12, 332373 (2002) doi:10.1006/acha.2002.0380

  Mathematics Websites

Summary: Research supported in part by DARPA Grants F49620-98-1-0491 and F30602-98-1-0154 and University of Virginia subcontract MDA972-00-1-0016. 2 Research supported in part by DARPA Grant F30602-98-1-0154. 332 1063

Beylkin, Gregory
2002-01-01

391

486 IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, VOL. 9, NO. 2, MARCH/APRIL 2003 Wavelength Division Multiplexed Optical

  Engineering Websites

Summary: Advanced Research Projects Agency (DARPA) under Ultra-Photonics Program Grant F49620-97-1-0517, by DARPA Grant MDA972-98-1-0002, by MARCO/DARPA Grant GIT-B-12-D00-S57, and a subaward from the University of New

Miller, David A. B.

392

2058 JOURNAL OF LIGHTWAVE TECHNOLOGY, VOL. 18, NO. 12, DECEMBER 2000 All-Optical Label Swapping Networks and

  Engineering Websites

Summary: review results of the DARPA Next Generation Internet program in all-optical label swapping at Uni, capacity, performance, and packet Manuscript received August 18, 2000. This work was supported by DARPA NGI (MDA972-99-1-0006), CISCO Systems, the DARPA Center on Multidisci- plinary Optical Switching Technology

Bowers, John

393

Computer Science and Artificial Intelligence Laboratory Technical Report

  Biology and Medicine Websites

Summary: was sponsored by grants from: Office of Naval Research (DARPA) Con- tract No. MDA972-04-1-0037, Office of Naval Research (DARPA) Contract No. N00014- 02-1-0915, National Science Foundation (ITR/SYS) Contract No. IIS

Poggio, Tomaso

394

Asymptotics of Gaussian Regularized Least-Squares

  Biology and Medicine Websites

Summary: (CSAIL). This research was sponsored by grants from Office of Naval Research (DARPA) Contract No. MDA972-04-1-0037, Office of Naval Research (DARPA) Contract No. N00014-02-1-0915, Na- tional Science Foundation-NIH (CRCNS

Poggio, Tomaso

395

brief communications 332 | VOL.10 NO.4 | APRIL2013 | nature methods

  Chemistry Websites

Summary: ). At a resolving power of 480,000, avail- able with current Fourier transform systems, >85% of identified peptides the fact that nuclear binding energy, the energy required to break down a nucleus into its component can be quantified (resolved) when spaced 18 mDa apart. With 960,000 resolving power, achievable

Cai, Long

396

Reflective Model Driven Engineering Jean Bezivin1

  Physics Websites

Summary: transformations al- lowing the engineers to more or less automatically go from platform- independent models (PIM that these transformations are not prisoners of a given CASE tool. Considering in this paper that a CASE tool can be seen as a platform for processing a model transformation, we propose to reflectively apply the MDA to itself. We

Paris-Sud XI, Université de

397

A Metamodeling Approach to Model Refactoring Sheena R. Judson1

  Computer Technologies and Information Sciences Websites

Summary: A Metamodeling Approach to Model Refactoring Sheena R. Judson1 , Doris L. Carver1 , and Robert USA france@cs.colostate.edu Abstract. The Model Driven Architecture (MDA) initiative formulated by the Object Management Group (OMG) provides a framework for a set of standards supporting a model

France, Robert B.

398

Rhizomatous plant Preparation

  Biology and Medicine Websites

Summary: Antioxidant Reducing agent Prevent oxidative DNA adducts Enol form of Curcumin #12;Will oral administration of curcumin 95 act as an anti-tumorogenic agent against MDA-MB- 231 breast cancer cells on nude mice (nu was able to be obtained regarding the anti-tumorigenic effects of curcumin through this study

Trask, Barbara Crippes

399

IEEE TRANSACTIONS ON EVOLUTIONARY COMPUTATION, VOL. 8, NO. 2, APRIL 2004 137 Systematic Integration of Parameterized Local Search

  Computer Technologies and Information Sciences Websites

Summary: Agency (DARPA) under Contract MDA972-00-1-0023 through Brown University. N. K. Bambha is with the Department of Electrical and Computer Engi- neering, University of Maryland, College Park, MD 20742 USA@eng.umd.edu). S. S. Bhattacharyya is with the Department of Electrical and Computer Engineering and the Institute

Bhattacharyya, Shuvra S.

400

Slicing of UML Models K. Lano, S. Kolahdouz-Rahimi

  Computer Technologies and Information Sciences Websites

Summary: -engineering and re-factoring of soft- ware. With the advent of UML and model-based development approaches such as Model-Driven Development (MDD) and Model-Driven Architecture (MDA), models such as UML class diagrams and state machines have become impor- tant artifacts within the development process, so that slicing

Lano, Kevin Charles

401

Joo Paulo Andrade Almeida Lus Ferreira Pires

  Engineering Websites

Summary: -Driven Architecture (3M4MDA), Bilbao, Spain, July 11, 2006 Proceedings Enschede, the Netherlands, 2006 CTIT Workshop in Bilbao, Spain, in conjunction with the European Conference on Model Driven Architecture - Foundations Instituut, the Netherlands Antonio Vallecillo University of Málaga, Spain Supporting Organisations Centre

Al Hanbali, Ahmad

402

Homomorphisms from sparse graphs with large girth

  Mathematics Websites

Summary: -0099608 and by INTAS grant 97-1001. Partially supported by NSA grant MDA904-03-1-0037. The U.S. grants of the NSF or NSA. 1 #12;uv E(G); a graph having such a coloring is (k, d)-colorable. Note that a (k, 1

West, Douglas B.

403

Graphic and Protographic Lists of Integers Dmitry Fon-Der-Flaass

  Mathematics Websites

Summary: upon work supported by NSA under Award No. MDA904-03-1-0037, which requires the disclaimer that any of the author(s) and do not necessarily reflect the views of the NSA. 1 #12;merger X Y is not graphic, where

West, Douglas B.

404

The Annals of Statistics 2007, Vol. 35, No. 3, 11051145

  Mathematics Websites

Summary: real functions g(X1,...,Xm) of m > 1 Received March 2005; revised May 2006. 1Supported in part by NSA Grant H98230-04-1-0075. 2Supported in part by NSA Grant MDA904-02-1-0034 and NSF Grant DMS-02-03865. AMS

Giné-Masdéu, Evarist

405

Graphic and Protographic Lists of Integers Dmitry Fon-Der-Flaass , Douglas B. West y

  Mathematics Websites

Summary: @math.uiuc.edu. This material is based upon work supported by NSA under Award No. MDA904-03-1-0037, which requires are those of the author(s) and do not necessarily re ect the views of the NSA. 1 #12; merger X [ Y

West, Douglas B.

406

http://www.elsevier.com/locate/jctb Journal of Combinatorial Theory, Series B 90 (2004) 147159

  Mathematics Websites

Summary: supported by NSF Grant DMS-0099608 and by INTAS grant 97-1001. 3 Partially supported by NSA Grant MDA904 reflect the views of the NSF or NSA. 0095-8956/$ - see front matter r 2003 Elsevier Inc. All rights

Kostochka, Alexandr V.
2004-01-01

407

DOI: 10.1007/s00208-005-0734-3 2 0 8 0 7 3 4

  Mathematics Websites

Summary: 92830-04-1-0027 from the National Security Agency. #12;2 B.C. Berndt, A. Zaharescu where, as customary-764, Bucharest RO-70700, Romania. (e-mail: zaharesc@math.uiuc.edu) Research partially supported by grant MDA H

Berndt, Bruce C.

408

2005 Nature Publishing Group *Department of

  Biology and Medicine Websites

Summary: .1038/nrm1701 PROTEASOME A large ~2.5-MDa multisubunit protein complex that binds to and subsequently degrades polyubiquitylated proteins. POLYUBIQUITIN CHAIN A string of ubiquitin molecules that are attached). Two proteins that need to bind to each other tempo- rarily can be linked by interactions between

Hill, Chris

409

Kerkrade, July 5-7, 2006 Pierre Laforcade 1 Next Step for Educational ModelingNext Step for Educational Modeling

  Computer Technologies and Information Sciences Websites

Summary: (Technology Enhanced Learning) driven by the usage analysis Strong interest about the design / analysis / re and results from the Model Driven Engineering (MDE) and Model Driven Architecture (MDA) domains for Educational Modeling Languages: The Model DrivenLanguages: The Model Driven Engineering

Laforcade, Pierre

410

Thse de doctorat Pour obtenir le grade de Docteur de l'Universit de

  Physics Websites

Summary: ) approach, independent of the domain application, allowing the design and the semi-automatic generation la personnalisation du contenu. Cette th`ese propose une approche de type MDA (Model Driven Architecture), ind´ependante du domaine d'application, permettant la conception et la g´en´eration semi

Paris-Sud XI, Université de

411

The relationship between follicle development and progesterone

  Biology and Medicine Websites

Summary: expression in women undergoing in vitro fertilization Alyaa Elassar, M.D.,a Xiufang Liu,b Victoria Scranton ovarian hyperstimulation (COH). Setting: Fertility center/basic science laboratory. Patient(s): Eighty of follicles develop to allow for ET and subsequent pregnancy. (Fertil SterilÒ 2012;97:572­8. Ó2012 by American

Terasaki, Mark

412

Building Songs 7

  University of Cambridge - Dspace

Summary: Date of recording October 28th 2009. Place of recording DzaM mda' Village, Phu ma Township, Sde dge County, Dkar mdzes Tibetan Autonomous Prefecture, Sichuan Province, China. Name(s), age, sex, place of birth of performer(s) Skar ma chos mdzin...

Zla ba sgrol ma
2009-10-28

413

Building Songs 5

  University of Cambridge - Dspace

Summary: Date of recording October 28th 2009. Place of recording DzaM mda' Village, Phu ma Township, Sde dge County, Dkar mdzes Tibetan Autonomous Prefecture, Sichuan Province, China. Name(s), age, sex, place of birth of performer(s) Skar ma chos mzdin...

Zla ba sgrol ma
2009-10-28

414

Building Songs 8

  University of Cambridge - Dspace

Summary: Date of recording October 28th 2009. Place of recording DzaM mda' Village, Phu ma Township, Sde dge County, Dkar mdzes Tibetan Autonomous Prefecture, Sichuan Province, China. Name(s), age, sex, place of birth of performer(s) Skar ma chos mzdin...

Zla ba sgrol ma
2009-10-28

415

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized

  Chemistry Websites

Summary: and convert it into the amino acid sequences of proteins. Ribosomes account for as much as 30% of total cell ribonucleoprotein complexes composed of two subunits with a total molecular mass ranging between B2.4 MDa (bacteria the distances between nascent chains emerging from neighboring ribosomes, thereby preventing unfavorable

Cai, Long

416

Measurement Limits to $^{134}$Cs Concentration in Soil

  CERN Preprints

Summary: We investigate the caesium concentrations in soils in mountain areas near Gori nuclear power plant in Korea, focusing on the measurement limits to the $^{134}\\mathrm{Cs}$. In order to lower the minimum detectable amount (MDA) of activity for the $134}\\mathrm{Cs}$, we have used the ammonium molybdophosphase (AMP) precipitation method to get rid of the $^{40}$K existing in natural radioactivity, which reduces the MDA of activity about ten times smaller than those without the AMP precipitation method. The MDA results for the $^{134}\\mathrm{Cs}$ were found to be in the range between 0.015 and 0.044 Bq/kg-dry weight. In order to diminish the background, we also have measured a part of the soil samples in Yangyang, a small town in the east coast of Korea. However, it turns out that in order to detect the $^{134}\\mathrm{Cs}$ in the samples the MDA should be reduced to the level of mBq/kg-dry weight.

Ahn, J K; Lee, H M; Kim, T H; Park, J N; Kang, Y S; Lee, H S; Kim, S J; Park, J Y; Ryu, S Y; Kim, H Ch; Kang, W G; Kim, S K
2009-01-01

417

Full length background papers can be found at globalhealthsciences.ucsf.edu/news-events/malaria-elimination-background-paper-series Review of mass drug administration and

  Biology and Medicine Websites

Summary: APRIL 2014 Full length background papers can be found at globalhealthsciences.ucsf.edu/news-events/malaria) was a component of many malaria elimination programs during the eradi- cation era, but since then the malaria century with · Mass drug administration (MDA) for malaria is not new--it has a long history of use

Mullins, Dyche

418

Cascaded GMW Sequences Andrew Klapper y A. H. Chan z Mark Goresky x

  Mathematics Websites

Summary: under Grant Number MDA904-91-H-0012. The United States Government is authorized to reproduce in many applications of modern communication systems. A new family of pseudorandom binary sequences function values are sought in many applications of modern communication systems. The class of binary

Klapper, Andy

419

On the Distribution for the Duration of a Randomized Leader Election Algorithm

  Computer Technologies and Information Sciences Websites

Summary: . \\Lambda This author's research has been supported by NSF grant DMS--9311367. y This author's research has been supported by NSA grant MDA904--92--H3086. z This author's research has been supported by NSF), and Pit­ tel (1985, 1986)]. Our approach here is mainly analytic and provides a mechanical way

Szpankowski, Wojciech

420

ORIGINAL ARTICLE Csk-binding protein (Cbp) negatively regulates epidermal growth

  Biology and Medicine Websites

Summary: -induced cell transformation by controlling Src activation LQ Jiang1,3 , X Feng1,3 , W Zhou1,3 , PG Knyazev4 EGFR-mediated cell signaling and promoting cell transformation and tumorigenesis in pathological enzymes, and NIH3T3 cell transformation, as well as colony formation of a breast cancer cell line (MDA- MB

Tian, Weidong

421

Structural characterization by cross-linking reveals the detailed architecture of a coatomer-related heptameric module from the nuclear pore complex

  Biotechnology Websites

Summary: -(3-dimethylaminopropyl) carbodiimide NPC: nuclear pore complex EM: electron microscopy Nup: nucleoporin VCC: vesicle assembly (~600 kDa), sixteen copies of which form the outer rings of the 50 MDa nuclear pore complex (NPC an evolutionary relationship between vesicle coating complexes and the NPC, and indicates a conserved mechanism

Sali, Andrej

422

Post-circuit blues: Motivations and consequences of crystal meth use among gay men

  CiteSeer

Summary: Miami, Florida was at the vanguard of the rise of circuit parties and attendant club drug use— especially ecstasy, GHB, and ketamine—in the 1990s. Crystal methamphetamine, a drug of abuse among gay men for some years on the West coast, gradually moved east toward the end of the decade and recently became prevalent in Miami. This paper reports the results of focus group research into the motivations and consequences of crystal use among gay men in this new setting. Loneliness, fears about physical attractiveness due to aging and illness, and desires to lose sexual inhibitions were common motivations for using the drug. Continued use of crystal was often described as the cause of lost friendships, employment and long-term relationships, as well as sexual behaviors that put men at risk for HIV and other sexually transmitted infections. Implications for drug and sexual risk prevention interventions are discussed. KEY WORDS: methamphetamine; drug use; gay men; HIV risk behavior. I told him before he moved to Miami Beach what was going to happen. Because I’ve seen this Beach spit so many, you know, chew them up and spit them

Steven P. Kurtz
2005-01-01

423

The pharmacology and toxicology of “ecstasy” (MDMA) and related drugs. CMAJ

  CiteSeer

Summary: "ECSTASY " (MDMA) AND RELATED DRUGS ARE AMPHETAMINE DERIVATIVES that also have some of the pharmacological properties of mescaline. They have become popular with participants in "raves, " because they enhance energy, endurance, sociability and sexual arousal. This vogue among teenagers and young adults, together with the widespread belief that "ecstasy " is a safe drug, has led to a thriving illicit traffic in it. But these drugs also have serious toxic effects, both acute and chronic, that resemble those previously seen with other amphetamines and are caused by an excess of the same sympathomimetic actions for which the drugs are valued by the users. Neurotoxicity to the serotonergic system in the brain can also cause permanent physical and psychiatric problems. A detailed review of the literature has revealed over 87 "ecstasy"-related fatalities, caused by hyperpyrexia, rhabdomyolysis, intravascular coagulopathy, hepatic necrosis, cardiac arrhythmias, cerebrovascular accidents, and drug-related accidents or suicide. The toxic or even fatal dose range overlaps the range of recreational dosage. The available evidence does not yet permit an accurate assessment of the size of the problem presented by the use of these drugs. Dr. Kalant is Professor

Harold Kalant
2001-01-01

424

Phenethylamines

  CiteSeer

Summary: n The majority of the world’s MDMA (‘ecstasy’) continues to be produced in Western Europe, with increases noted in Eastern Europe, South East Asia and Canada. n The majority of MDMA border detections (by number) occurred in the postal stream, whereas the largest proportion (by weight) was detected in sea cargo. n What appears to be a large reduction in the weight of border detections of MDMA is attributable to the high weight of seizures in the previous reporting year. Main Forms Phenethylamines are a group of synthetic drugs which exhibit chemical similarity to amphetamines. As defined in the Australian Bureau of Statistics (ABS) Australian Standard Classification of Drugs of Concern, phenethylamines include 3,4-methylenedioxymethylamphetamine (MDMA) or ‘ecstasy ’ and its derivatives (ABS, 2000). MDMA is a central nervous system stimulant and has both hallucinogenic and ephedrine-like effects (Johnson, Maxwell and Leitnerschmidt, 1997). Although chemically related to amphetamine, MDMA is not a derivative and is produced by a different chemical process. In its base form, MDMA is an oil which can be converted into powder for inclusion into tablets or capsules. MDMA tablets usually feature a symbol or logo from popular culture, such as logos from clothing labels, car manufacturers or other desirable items. Table 6 details common types of phenethylamines used in Australia.

Key Points; Snacks Hug Beans

425

Phenethylamines Description

  CiteSeer

Summary: • Although little evidence of MDMA (‘ecstasy’) production in Australia was found during 2001–02, the production of ‘fake ecstasy’ continued. • The number of methylamphetamine pills being misrepresented as MDMA decreased during 2001–02. • While MDMA production remains focused in Western and Eastern Europe, there was a significant increase in detections of phenethylamines transhipped via Asian countries. • The total weight of seized phenethylamine importations increased from 338.4 kilograms in 2000–01 to 445 kilograms in 2001–02. • The popularity of MDMA among users continued to increase in 2001–02. Availability of MDMA also increased during the period, specifically sourced from friends, acquaintances and lower level dealers. ‘Ecstasy ’ or MDMA (3,4-methylenedioxy methylamphetamine) belongs to the family of drugs known as phenethylamines and shares a chemical similarity to the stimulant amphetamine and the hallucinogen mescaline (Koesters, Rogers & Rajasingham 2002). MDMA, a synthetic drug, is a central nervous system stimulant and has both hallucinogenic and ephedrine-like effects (TCADA 2002). Although chemically related to amphetamine, MDMA is not a derivative and is produced by a different chemical

Key Points

426

A new approach of designing Multi-Agent Systems

  CERN Preprints

Summary: Agent technology is a software paradigm that permits to implement large and complex distributed applications. In order to assist analyzing, conception and development or implementation phases of multi-agent systems, we've tried to present a practical application of a generic and scalable method of a MAS with a component-oriented architecture and agent-based approach that allows MDA to generate source code from a given model. We've designed on AUML the class diagrams as a class meta-model of different agents of a MAS. Then we generated the source code of the models developed using an open source tool called AndroMDA. This agent-based and evolutive approach enhances the modularity and genericity developments and promotes their reusability in future developments. This property distinguishes our design methodology of existing methodologies in that it is constrained by any particular agent-based model while providing a library of generic models

Maalal, Sara
2012-01-01

427

The asymptotic number of set partitions with unequal block A. Knopfmacher

  Mathematics Websites

Summary: @gauss.cam.wits.ac.za A. M. Odlyzko AT&T Labs ­ Research Florham Park, New Jersey 07932, USA e­mail: amo, and under NSA Grant MDA 904­96­1­0053. 2 Current address: BRIMS, Hewlett­Packard Labs, Filton Road, Stoke:529477 : : : : The next smallest singularities are the first order poles at \\Sigma p 2. Therefore [z n ]G

Odlyzko, Andrew M.

428

Local History

  University of Cambridge - Dspace

Summary: last updated by World Oral Literature Project staff on Wednesday, Tuesday, June 8, 2010 Accession Form for Individual Recordings: Collection / Collector Name Oral literature of the Sman shad Valley/ Zla ba sgrol ma. Tape No. / Track / Item No... , 1948 provides details on local history. Genre or type (i.e. epic, song, ritual) Interview Name of recorder (if different from collector) Zla ba sgrol ma Date of recording November 17th 2009. Place of recording Dzong sar Monastery, Mda' ma...

Zla ba sgrol ma
2009-11-17

429

FLIP CRUISE SUMMARY 1985-2012 Year U/W Dates P. I./Org. Contract Program/Evolution

  Geosciences Websites

Summary: ) MDA972-93-0003 ATOC experiment 2 point moor/SOCAL Navajo 5 1994 total 83 18 Jan-14 Feb Gaines (MPL'Spain (MPL) MPL WH 66 SWellEx engineering test/FOPAR radar/moored 3 SOCAL/commercial tug Recovery One 9 18 Jul-4 Aug Hodgkiss MPL/NRaD) MPL WH 11 SWellEX3/moored 3 SOCAL/Navajo 18 29 Aug-7 Sep Friehe (UCI

Smith, Jerome A.

430

Motile Properties of Cytoplasmic Dynein Samara L. Reck-Peterson,a Ronald D.Vale,b and Arne Gennerichc

  Biology and Medicine Websites

Summary: cofactors, the dynactin complex, LIS1, and NudE. 8.1 IntroDuCtIon Cytoplasmic dynein (referred to as dynein complex, LIS1, and NudE. One of the challenges for studying the motile properties of dynein has been its complex, LIS1, and NudE brings the total complex size to ~2.5 MDa. The HC itself is quite complicated


431

September 15, 2009 Volume 3, Issue 20

  Biology and Medicine Websites

Summary: turnout for this meeting on 9/24, please email Paul Jenkins at jenki132@msu.edu if you plan to attend (and/24, please email Paul Jenkins at jenki132@msu.edu if you plan to attend (and indicate how many people). Agenda Facilitator: Paul Jenkins, MSU 9:00-9:05 Welcome John Wise, MSU 9:05-9:20 MDA-MSU response

Isaacs, Rufus

432

VERTEX DEGREES IN PLANAR GRAPHS Douglas B. West #

  Mathematics Websites

Summary: whether f(n, k) # 2n for su#ciently large fixed k; the answer is no. For k # 12 we prove: f(n, k answers for all n when k # 12 and special congruence classes of n when 6 # k # 11. For k in part by NSA/MSP Grant MDA904­90­H­4011. + Supported by Title IX Accelerated Doctoral Fellowship

West, Douglas B.

433

CART and MARS For an example, take the STAT 100 students' data (N = 136), and try to predict BMI

  Mathematics Websites

Summary: CART and MARS For an example, take the STAT 100 students' data (N = 136), and try to predict BMI.0657 Or looking at the actual function and its estimate: 3 #12;z0 Y Z True function 4 #12;zztree Y Z Tree MARS The MARS function is in the package mda. It uses the (x,y) form for the arguments, rather than the (y x

Zeng, Donglin

434

Invitro Effect of Papaverine on Lipid Peroxidation in Sickle Cell Anaemia ABSTRACT

  CiteSeer

Summary: Disruption in erythrocyte membrane Ca 2+ ATPase activity in sickle cell anaemia is linked to increase in lipid peroxidation product, malondialdehyde (MDA). Some drugs are known to inhibit the Ca 2+ ATPases therefore, the study was undertaken to evaluate the effect of Papaverine a known Ca 2+ channel inhibitor on the level of MDA and plasma calcium in sickle cell anaemia. The MDA concentrations of the sickle cell homozygous group before and after incubation (17.00±0.30nmol/l and 11.20±0.39nmol/l respectively) were significantly higher (p<0.05) when compared to groups AA (13.30±0.32nmol/l and 6.66±0.42nmol/l) and SS (11.20±0.39nmol/l and 6.80±0.44nmol/l). MDA concentration decreased significantly in all the groups after incubation with Papaverine. The SS group showed the least inhibition (35.29±0.36%) with Papaverine which is significant (p<0.05) when compared to groups AA (49.92±0.38%) and AS (39.29±0.40%). Plasma calcium concentrations before and after incubation with Papaverine were significantly higher (p<0.05) in SS group (12.8±0.42mg/dl and 9.00±0.14mg/dl respectively) when compared to groups AA (11.45±0.49mg/dl and7.14±0.21mg/dl) and AS (8.25±0.35mg/dl and 6.15±0.07mg/dl).

unknown authors

435

Journal of Combinatorial Theory, Series B 96 (2006) 374387 www.elsevier.com/locate/jctb

  Mathematics Websites

Summary: Technologies and at Institute for Advanced Study, supported in part by NMIMT/ICASA grant MDA904-01-C-0327. 0095. The tournament T realized by the orders P1, . . . , P2k-1 is the tournament on V in which an ordered pair uv that for every edge uv, u lies above v in at least k + (k/ n) of the orders. This paper is concerned

Kostochka, Alexandr V.
2006-01-01

436

L2B-processor status Jos de Kloe, KNMI,

  Geosciences Websites

Summary: ADM-Aeolus L2B-processor status Jos de Kloe, KNMI, Gert-Jan Marseille, KNMI, Paul Poli, MF, David Tan, ECMWF, 22-May-2007 #12;L2B-PM9, J. de Kloe, G.J. Marseille, P. Poli, D. Tan, 22 May 2007 2 L2BP status (summary) Main changes from release 1.2 to 1.3 L1B file reader tested to be compatible with MDA L1

Stoffelen, Ad

437

Idathu padam Thooki aadum Ragam: Khamas {28th Melakartha (Kharaharapriya) Janyam}

  Computer Technologies and Information Sciences Websites

Summary: ; | ; ; ; ; || I Da du pa dam tU- - kki A- - Dum - - - - #12;Oh mind ("nenje"), bow ("panivaye") before the feet | pm N D ; | ; ; P D || iDa du pa dam tU- - kki A- - Dum - - naTa sn rs , n D P ­ M P nd | pmmg MDa du pa dam tU- - kki A- - Dum - - naTa sn rs , n D P ­ M P nd | pmmg M ; ; | ; ns nd ­ dp || r

Kalyanaraman, Shivkumar

438

SUPPLEMENTAL FIGURES Fig. S1. The ER inhibitor ICI 182,780, decreases PR-mediated gene expression in T47D

  Chemistry Websites

Summary: in ER negative MDA-MB-231 cells. Cell maintenance, growth and plating were as described in the Fig. 4 but not OHT inhibits E2-ER-dependent growth of MCF7ERHA cells. MCF7ERHA cells were maintained for 4 days in 6x on the levels of AR and GR. The cell lines used and cell growth conditions were those employed in the dose

Hergenrother, Paul J.

439

A SoC Design Methodology Involving a UML 2.0 Profile for SystemC E. Riccobene1

  Physics Websites

Summary: A SoC Design Methodology Involving a UML 2.0 Profile for SystemC E. Riccobene1 , P. Scandurra1 , A.rosti,sara.bocchio}@st.com Abstract In this paper, we present a SoC design methodology joining the capabilities of UML and SystemC to operate at system- level. We present a UML 2.0 profile of the SystemC language exploiting the MDA

Paris-Sud XI, Université de

440

Optimal Routing and SINR Target Selection for Power-Controlled CDMA Wireless Networks

  Computer Technologies and Information Sciences Websites

Summary: in code-division multiple access (CDMA) wireless data networks. In CDMA systems, the capacity of a link-01-1-0365, by DARPA contracts F33615-99-C-3014 and MDA972-02-1-0004 and by MARCO con- tract 2001-CT-888. 2.1 Network across the network, whose entry Gi j is the power gain from the transmitter of link j to the re- ceiver

Boyer, Edmond

441

The Asymmetric Drift of the Thick Disk Population

  Astrophysics (arXiv)

Summary: We investigate the kinematics of the intermediate population using the photometric and astrometric sample surveys towards two opposite directions (galactic centre and anticentre) at intermediate latitude. A multivariate discriminant analysis (MDA) is used to distinguish the `Thick Disk' from other populations with the help of the Besan\\c con model of population synthesis. The data constrain the asymmetric drift of the intermediate population, which is found to be 40$\\pm$10 km sec$^{-1}$ and does not depend on the galactic radius.

Devendra Ojha; Annie C. Robin; Olivier Bienayme
1994-08-21

442

The International Journal of Biochemistry & Cell Biology 39 (2007) 93108 Regulation of acetylcholinesterase expression by calcium

  Biology and Medicine Websites

Summary: -induced apoptosis Hui Zhua, Wei Gaoa, Hua Jianga, Qi-Huang Jina, Yu-Fang Shib, Karl W.K. Tsimc, Xue-Jun Zhanga for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 320 YueYang by the mobilization of intracellular Ca2+ . During apoptosis, treatment of HeLa and MDA-MB-435s cells with the calcium

Tian, Weidong
2007-01-01

443

Research Article Phosphocreatine Preconditioning Attenuates Apoptosis in Ischemia-Reperfusion Injury of Rat Brain

  CiteSeer

Summary: Copyright © 2011 Ling-Hua Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Phosphocreatine (PCr) is an endogenous compound containing high-energy phosphate bonds. It has been confirmed that PCr is effective in preventing and treating cardiac and renal ischemia-reperfusion injury. In this study, rat cerebral ischemia-reperfusion injury models were constructed. Apoptotic cells in the cortex region were measured by TUNEL method. Malondialdehyde (MDA) content was detected by chromatometry, and calmodulin (CaM) activity was detected by ELISA. Compared with sham-operated group (sham group), TUNEL-positive cells, MDA, and level of CaM activity increased in ischemia-reperfusion group (I/R group) and PCr preconditioning group (PCr group); compared with I/R group, TUNEL-positive cells, MDA content, and level of CaM activity decreased in PCr group. This study indicated that PCr can decrease the morphological damage and the neuron apoptosis of the ischemia-reperfusion injury brain through attenuating abnormalities of calcium balance and production of oxygen free radicals. 1.

Ling-hua Tang; Zhong-yuan Xia; Bo Zhao; Xiao-dong Wei; Tao Luo; Qing-tao Meng
2010-01-01

444

Attenuation study for Tibet Water Cherenkov Muon Detector Array-A

  HEP - Experiment (arXiv)

Summary: This work aims at online calibrating the signal attenuation of the long cable used in Tibet Water Cherenkov Muon detector array-A (Tibet MD-A) under the 37 000 m2 Tibet air shower array. Based on the waterproof connection of the PMT (R3600_06) with the signal cable, and the characters of the high voltage divider, terminal reflection method is explored and used for measuring the signal attenuation with a practical way to eliminate the contribution of the pulse baseline (pedestal). Comparison measurement between it and QDC (Charge-to-Digital Conversion) data taking method are carried out by using open-ended cables, confirming that terminal reflection method is a fast and convenient method, and suitable to online calibrate the signal attenuation for Tibet MD-A. At 26\\degree C, the measured attenuation coefficient with the 250-m cable, permanently connected to the PMT, is ~13.9%. Also, the cable frequency response is measured by using the sinusoidal signals, which could be used to study the time dispersion of the real signal produced with Tibet MD-A detector via Fourier analysis.

Quanbu Gou; Yiqing Guo; Cheng Liu; Xiangli Qian; Zhengtao Hou
2011-08-14

445

Stimulant ADHD Medications:

  CiteSeer

Summary: Stimulant medications (e.g., methylphenidate and amphetamines) are often prescribed to treat individuals diagnosed with attention-deficit hyperactivity disorder (ADHD). ADHD is characterized by a persistent pattern of inattention and/or hyperactivity-impulsivity that is more frequently displayed and more severe than is typically observed in individuals at a comparable level of development. This pattern of behavior usually becomes evident in the preschool or early elementary years, and the median age of onset of ADHD symptoms is 7 years. For many individuals, ADHD symptoms improve during adolescence or as age increases, but the disorder can persist into adulthood. In the United States, ADHD is diagnosed in an estimated 8 percent of children ages 4–17 and in 2.9–4.4 percent of adults. 1,2,3

unknown authors

446

Orignal Research Characteristics of Methylphenidate Misuse in a University Student Sample

  CiteSeer

Summary: Methylphenidate is a stimulant medication widely usedfor treating ADHD. Despite its wide margin of safety, MPH is thought to have high abuse potential (1). Cases of oral (2,3), intranasal (4,5), and intravenous (6,7) MPH abuse have been documented. However, consistent information is lacking regarding the prevalence of MPH abuse through the various routes of administration or regarding its use in a polysubstance context. Although rates of MPH abuse are thought to be lower than rates for other stimulants, it has been suggested that MPH misuse may be underreported (1). In a college student sample, rates of reported recreational MPH use among traditional-age students were comparable to rates of cocaine and amphetamine use, but any overlap in the rates of MPH and other stimulant use was not specified (8). A study Can J Psychiatry, Vol 50, No 8, July 2005 457 Objective: Methylphenidate (MPH) is a prescription stimulant drug with known abuse potential; however, little is

Sean P Barrett; Phd C; Christine Darredeau; Phd C; Lana E Bordy; Robert O Pihl

447

How Do Prescription

  CiteSeer

Summary: Stimulant medications (e.g., methylphenidate and amphetamines) are often prescribed to treat individuals diagnosed with attention-deficit hyperactivity disorder (ADHD). ADHD is characterized by a persistent pattern of inattention and/or hyperactivity-impulsivity that is more frequently displayed and more severe than is typically observed in individuals at a comparable level of development. This pattern of behavior usually becomes evident in the preschool or early elementary years, and the median age of onset of ADHD symptoms is 7 years. For many individuals, ADHD symptoms improve during adolescence or as age increases, but the disorder can persist into adulthood. In this country, ADHD is diagnosed in an estimated 8 percent of children ages 4–17 and 2.9–4.4 percent of adults. 1,2,3

unknown authors

448

Other drugs Other drugs Principal findings

  CiteSeer

Summary: ? There were 968 performance-enhancing drug detections at the Australian Customs border in 1998–99, a 73.4 per cent increase on the 558 in 1997–98. ? The incidence of polydrug use is increasing in Australia including pharmaceuticals being used in conjunction with illicit substances such as heroin and amphetamine type substances. ? Australian health authorities, researchers and law enforcement agencies report an increasing trend in the injection of broken down prescription pills, tablets and capsules among injecting drug users. ? Australian health authorities, researchers and law enforcement agencies have found that the use of hallucinogens (including LSD), and the abuse of morphine-base tablets and capsules increased in 1998–99.

unknown authors

449

Polish Academy of Sciences Review Role of serotonin (5-HT)1B receptors in psychostimulant addiction

  CiteSeer

Summary: Psychostimulant (cocaine, amphetamine and its derivatives) addiction is an important health problem with implications in social and economic life. Although mesocorticolimbic dopamine system plays a crucial role in the mechanism responsible for the rewarding effects of these drugs, recent data also show involvement of the brain serotonin (5-HT) system. In the present review we discuss the role of 5-HT1B receptors in the psychostimulant addiction on the base of the effects of 5-HT1B receptor ligands on the behavioral effects of the psychostimulants in experimental models (sensitization, intracranial self-stimulation, conditioned place preference, self-administration and extinction/reinstatement model) used to assess their addictive properties. Moreover, the effect of long-term treatment with psychostimulants on 5-HT1B receptors is also discussed. Key words: 5-HT * receptors, psychostimulants, behavioral models of drug addiction

Joanna Miszkiel; Edmund Przegaliñski

450

ABUSE OF MONOAMINE OXIDASE INHIBITORS

  CiteSeer

Summary: Abuse of monoamine oxidase inhibitors is not common but there are a few cases of addiction in the literature. Most of these patients had an additional diagnosis, either history of past drug abuse or personality disorder and MAOI withdrawal symptoms have been reported. We encountered three patients who received MAOI under psychiatric care. They were all self medicated by increasing tlie doses on their own, experienced euphoria and visited various physicians to obtain MAOI prescriptions and manifested toxic states. One of our patients had a normal, another a schizoid and the third, an addictive personality. Two were addicted in the past to amplietamine. Therefore, it is important not to prescribe MAOI's to patients who have a history of amphetamine and other addictions. Key words: Monoamine oxidase inhibitors, MAOI, Monoamine oxidase inhibitor addiction

Jambur Ananth; J. Randolph Swartz; Rangaswamy Gadasally; Karl Burgoyne

451

Polish Academy of Sciences Effects of melatonin in a place preference

  CiteSeer

Summary: A conditioned place preference paradigm was used to assess potential rewarding properties of melatonin. The conditioning with melatonin was carried out at two periods of the 12-h light/dark cycle: in the morning (08.30–10.00) and in the evening (18.30–20.00). Morning administration of melatonin (2.5, 5 and 10 mg/kg) did not support conditioned place preference. In contrast, evening conditioning with melatonin caused a clear shift towards the drug-paired side. This effect was dose-dependent; higher doses of 2.5, 5, 10 and 50 mg/kg induced conditioned preference while lower doses of 0.5 and 1 mg/kg were ineffective. The increase in the side preference induced by the two most effective doses of melatonin (10 and 50 mg/kg) were comparable to that induced by 1 mg/kg of amphetamine, and was significantly attenuated by the melatonin antagonist, S 22153 (20 mg/kg). In chronic experiment, melatonin (10 mg/kg) caused similar increase of the time spent on conditioned side both in animals administered vehicle for 7 days and in rats receiving 10 mg/kg of melatonin for the same period of time. Potent activity in the conditioned preference model suggests that melatonin may have rewarding properties, which moreover, is not tolerated following repeated pre-exposure to the drug. These findings may indicate potential abuse liability of melatonin, and therefore, its use by humans should require a careful monitoring for abuse and/or dependency. Key words: conditioned preference, reward, melatonin, S 22153, amphetamine, acute and repeated administration, circadian, rats


2010-01-01

452

A Folk Tale of the Trickster Mching nges

  University of Cambridge - Dspace

Summary: last updated by World Oral Literature Project staff on Wednesday, Tuesday, June 8, 2010 Accession Form for Individual Recordings: Collection / Collector Name Oral literature of the Sman shad Valley/ Zla ba sgrol ma. Tape No. / Track / Item No... ) This folktale describes the exploits of the trickster Mchig nges. Genre or type (i.e. epic, song, ritual) Folk tale Name of recorder (if different from collector) Zla ba sgrol ma Date of recording November 17th 2009. Place of recording Ra'i kha , Mda...

Zla ba sgrol ma
2009-11-17

453

Local Home Remedies

  University of Cambridge - Dspace

Summary: last updated by World Oral Literature Project staff on Wednesday, Tuesday, June 8, 2010 Accession Form for Individual Recordings: Collection / Collector Name Oral literature of the Sman shad Valley/ Zla ba sgrol ma. Tape No. / Track / Item No... Dben zen discusses a number of local home remedies. Genre or type (i.e. epic, song, ritual) Interview Name of recorder (if different from collector) Zla ba sgrol ma Date of recording November 17th 2009. Place of recording Ra'i kha , Mda' ma...

Zla ba sgrol ma
2009-11-17

454

Efficacy and Toxicity of Peritumoral Delivery of Nanoconjugated Cisplatin in an In Vivo Murine Model of Head and Neck Squamous Cell Carcinoma

  University of Kansas - KU ScholarWorks

Summary: University of Kansas HQ User on 04/22/2013 umn distinctly visible; 2, themouse is underconditioned with a segment of vertebral column visible; 3, the mouse is well conditioned; 4, themouse is overconditioned; and 5, the mouse is obese. In this examination... and treatment arms were initiated once tumor vol- umes reached 30 mm3. Intervention: Injection with MDA-1986 HNSCC cells followed by 3 weeks of treatment with cisplatin, HA- cisplatin, phosphate-buffered saline, or HA only. Main Outcomes andMeasures: Animal...

Forrest, Marcus Laird
2013-04-01

455

Com pone nts J a v a .ne t

  Computer Technologies and Information Sciences Websites

Summary: M ode ls X M L IR M L Com pone nts E x e J a v a .ne t IR S ys te m X Te m pla te s G e ne ra l IR Te m pla te s Aplic a tionTe m pla te s Conc e ptua l IR S ys te m b a se d b a se d l i n ke r co d-based approach (MDA) for the design and creation of Information Retrieval (IR) systems. This is based

da Silva, Alberto Rodrigues

456

Research Article Biological Sciences IN VIVO RADIO PROTECTIVE PROPERTIES OF FUNGAL POLYSACCHARIDES

  CiteSeer

Summary: In vivo radio protective properties of polysaccharides isolated from Ganoderma lucidum, a macro fungi was examined. Swiss albino mice were exposed to 4 Gy gamma irradiation. Serum lipid peroxidation and tissue GSH were taken end points on 1 st, 3rd, 5th, 7th and 9 th day after irradiation. Polysaccharides were administered just after irradiation at 10 and 20 mg/kg body wt. Administration of polysaccharides reduced the Serum MDA levels compared to the irradiated group. Tissue GSH was maintained at normal levels after administration of polysaccharides. The polysaccharides possess radio protective property.

Thulasi G. Pillai A; K. K. Janardhanan B

457

Kinematical Properties of the Thick Disk of the Galaxy

  Astrophysics (arXiv)

Summary: We try here to find new constraints on thick disk population using samples at intermediate latitude and North Galactic Pole, which include photometry and proper motions. The algorithm SEM (Stochastic-Estimation-Maximization; Celeux \\& Deibolt 1986) was used to deconvolve the stellar components up to large distances above the plane, allowing to study of their statistical properties independently. The multivariate discriminant analysis (MDA) is used to qualify the thick disk using observations in multidimensional space (V,B-V,U-B, $\\mu_{l}$ \\& $\\mu_{b}$).

Devendra Ojha
1994-10-20

458

Un cadre de conception pour r\\'eunir les mod\\`eles d'interaction et l'ing\\'enierie des interfaces

  CERN Preprints

Summary: We present HIC (Human-system Interaction Container), a general framework for the integration of advanced interaction in the software development process. We show how this framework allows to reconcile the software development methods (such MDA, MDE) with the architectural models of software design such as MVC or PAC. We illustrate our approach thanks to two different types of implementation for this concept in two different business areas: one software design pattern, MVIC (Model View Interaction Control) and one architectural model, IM (Interaction Middleware).

Lard, Jérôme; Grisvard, Olivier; Faure, David
2008-01-01

459

Names and Titles in Early Tibetan Records

  University of Cambridge - Dspace

Summary: with its special insignia consisting of ornaments and diplomas of different precious substances. In general the highest was turquoise. followed by gold, 'phra men, silver, brass, and copper t LINV 1071); but in THA p.60 there is mention of ke ke ru... as the insignia of an award of special merit, apparently higher even than turquoise. Ke ke ru is described in Jaeschke's Dictionary as "a precious white stone"; perhaps it was jade or some hard stone. During recent road-making work near Rgya Mda' an ancient...

Richardson, Hugh Edward
1967-02-10

460

Meta-Model and Model Co-evolution within the 3D Software Space

  CiteSeer

Summary: Software evolution-in-the-large is a challenging issue. While most research work concentrates on the evolution of "programs", large scale software evolution should be driven by much higher levels of abstraction. Software architecture is an example of such abstraction. The notion of co-evolution between architecture and implementation has been identified and studied recently. This paper claims that other abstraction dimensions should also be taken into account, leading to what we call the 3D software space. This conceptual framework is used to reason about evolution-in-the-large phenomena occurring in industry. The meta dimension, which constitutes the core of the MDA approach, is considered as fundamental. This paper makes the distinction between appliware and metaware and put the lights on meta-model and model co-evolution. Conversely to the MDA approach which makes the implicit assumption that meta-models are neat, stable and standardized, in this paper meta-models are considered as complex evolving software artefacts that are most often recovered from existing metaware tools rather than engineered from scratch. In fact, we identified the notion of meta-model and model co-evolution in the context of the evolution of a multimillion LOC component-based software developed by one of the largest software companies in Europe.

Jean-Marie Favre
2003-01-01

461

First experiments with the ATL model transformation language: Transforming XSLT into XQuery

  CiteSeer

Summary: ATL (Atlas Transformation Language) has been defined to perform general transformations within the MDA framework (Model Driven Architecture) recently proposed by the OMG. We are currently learning from the first applications developed with this language. The example used here is a transformation from XSLT to XQuery. Since these are two standard notations that don’t pertain to the MDA space, we first need to provide some justification about this work. The global organization of technological spaces presented at the beginning of the paper is intended to answer this first question. Furthermore we propose the original characterization of a technological space as a framework based on a given unique meta-model. After having briefly presented the ATL framework, we describe the XSLT2XQuery transformation. We may then draw several conclusions from this experiment, suggesting possible improvements to general model transformation frameworks. ATL is still evolving since it is supposed to match the forthcoming QVT/RFP recommendation when it is ready. As a consequence, the concrete expression of the transformation presented in this paper may change, but the general ideas should remain stable.

Jean Bézivin; Grégoire Dupé; Frédéric Jouault; Gilles Pitette; Jamal Eddine Rougui
2003-01-01

462

Attenuation study for Tibet Water Cherenkov Muon Detector Array-A

  CERN Preprints

Summary: The attenuation study of the long cable used in Tibet Water Cherenkov Muon Detector Array-A, called Tibet MD-A (one of 12 Tibet MD detectors), under the 37000 m2 Tibet air shower array, is reported. The cable frequency response is measured by using the sinusoidal signals, with which the influence of the cable on the pulse rise time is obtained. For the reason that the commercial 20 inch PMT (R3600_06) has a waterproof connection with the signal cable, one end of the signal cable is permanently connected to the PMT. Terminal reflection method is tested and used for measuring the signal attenuation. During the measurement, a practical way to eliminate the uncertainty caused by the baseline of the signal is achieved. To check the terminal reflection method, comparison measurement between it and QDC data taking method are carried out by using open-ended cables. The confirmed terminal reflection method is a fast and convenient method being suitable to online measure the signal attenuation for Tibet MD-A. The measu...

Gou, Quanbu; Liu, Cheng; Feng, Zhaoyang; Qian, Xiangli; Hou, Zhengtao
2011-01-01

463

Manufacture of Sb-Based Type II Strained Layer Superlattice Focal Plane Arrays

  CiteSeer

Summary: Infrared sensors are very important to military sensing systems for target acquisition, tracking, discrimination and aim point selection. Most current infrared military systems use mercury-cadmium-telluride (HgCdTe), a II-VI semiconductor material, for long-wavelength (LW) (8-12 µm) focal plane arrays (FPAs). HgCdTe has difficulty in achieving large format FPAs at long wavelengths due to its low yield, aggravated by the limitation of the small cadmium-zinc-telluride (CdZnTe) substrates. Antinomide (Sb)-based type II strained layer superlattice (SLS) has the potential to perform better than HgCdTe, and at a lower cost by leveraging the commercial III-V foundries for manufacturing. The Missile Defense Agency Advanced Technology Directorate (MDA/DV) has been developing SLS material for the past few years and has made significant progress. The success in SLS LW has warranted a new SLS program at MDA to address SLS manufacturing issues. This program promotes horizontal integration of IR sensors instead of the current IR FPA fabrication approach, which is vertically integrated within one company. This paper will give the most recent progress made in SLS and describe the new approach of the SLS manufacturing program.

Meimei Z. Tidrow; Lucy Zheng; Hank Barcikowski; James Wells; Leslie Aitcheson; Layer Superlattice Qwips

464

Neurotoxins: Free Radical Mechanisms and Melatonin Protection

  CiteSeer

Summary: Abstract: Toxins that pass through the blood-brain barrier put neurons and glia in peril. The damage inflicted is usually a consequence of the ability of these toxic agents to induce free radical generation within cells but especially at the level of the mitochondria. The elevated production of oxygen and nitrogen-based radicals and related non-radical products leads to the oxidation of essential macromolecules including lipids, proteins and DNA. The resultant damage is referred to as oxidative and nitrosative stress and, when the molecular destruction is sufficiently severe, it causes apoptosis or necrosis of neurons and glia. Loss of brain cells compromises the functions of the central nervous system expressed as motor, sensory and cognitive deficits and psychological alterations. In this survey we summarize the publications related to the following neurotoxins and the protective actions of melatonin: aminolevulinic acid, cyanide, domoic acid, kainic acid, metals, methamphetamine, polychlorinated biphenyls, rotenone, toluene and 6-hydroxydopamine. Given the potent direct free radical scavenging activities of melatonin and its metabolites, their ability to indirectly stimulate antioxidative enzymes and their efficacy in reducing electron leakage from mitochondria, it would be expected that these molecules would protect the brain from oxidative and nitrosative molecular mutilation. The studies summarized in this review indicate that this is indeed the case, an action that is obviously assisted by the fact that melatonin readily crosses the blood brain barrier.


465

RESEARCH ARTICLE Open Access Cocaine use during pregnancy assessed by hair analysis in a Canary Islands cohort

  CiteSeer

Summary: Background: Drug use during pregnancy is difficult to ascertain, and maternal reports are likely to be inaccurate. The aim of this study was to estimate the prevalence of illicit drug use among pregnant women by using maternal hair analysis. Methods: A toxicological analysis of hair was used to detect chronic recreational drug use during pregnancy. In 2007, 347 mother-infant dyads were included from the Hospital La Candelaria, Santa Cruz de Tenerife, Canary Islands (Spain). Data on socioeconomic characteristics and on substance misuse during pregnancy were collected using a structured questionnaire. Drugs of abuse: opiates, cocaine, cannabinoids and amphetamines were detected in maternal hair by immunoassay followed by gas chromatography-mass spectrometry for confirmation and quantitation. Results: Hair analysis revealed 2.6 % positivity for cocaine and its metabolites. Use of cocaine during pregnancy was associated with unusual behaviour with potentially harmful effects on the baby. Conclusions: The results of the study demonstrate significant cocaine use by pregnant women in Canary Islands. The data should be used for the purpose of preventive health and policy strategies aimed to detect and possibly to avoid in the future prenatal exposure to drugs of abuse. Background

Xavier Joya; Mario Gomez-culebras; Alicia Callejón; Bibiana Friguls; Carme Puig; Ra Ortigosa; Luca Morini; Oscar Garcia-algar; Oriol Vall

466

ORIGINAL ARTICLE Eating and Hypothalamus Changes in

  CiteSeer

Summary: Objective: Behavioral-variant frontotemporal dementia (bvFTD) is a progressive neurodegenerative brain disorder, clinically characterized by changes in cognition, personality, and behavior. Marked disturbances in eating behavior, such as overeating and preference for sweet foods, are also commonly reported. The hypothalamus plays a critical role in feeding regulation, yet the relation between pathology in this region and eating behavior in FTD is unknown. This study aimed to address this issue using 2 complementary approaches. Methods: First, 18 early stage bvFTD patients and 16 healthy controls underwent high-resolution structural magnetic resonance imaging and assessment of eating behavior. Hypothalamic volumes were traced manually on coronal images. Second, postmortem analyses of 12 bvFTD cases and 6 matched controls were performed. Fixed hypothalamic tissue sections were stained for a cell marker and for peptides regulating feeding behaviors using immunohistochemistry. Stereological estimates of the hypothalamic volume and the number of neurons and glia were performed. Results: Significant atrophy of the hypothalamus in bvFTD was present in both analyses. Patients with high feeding disturbance exhibited significant atrophy of the posterior hypothalamus. Neuronal loss, which was observed only in bvFTD cases with Tar DNA protein-43 deposition, was also predominant posteriorly. In contrast, orexin (hypocretin), neuropeptide Y, cocaine- and amphetamine-regulating transcript, and vasopressin-containing neurons that regulate

Behavioral-variant Frontotemporal; Glenda M. Halliday

467

The Gemini NICI Planet-Finding Campaign: The Frequency of Giant Planets Around Debris Disk Stars

  CERN Preprints

Summary: We have completed a high-contrast direct imaging survey for giant planets around 57 debris disk stars as part of the Gemini NICI Planet-Finding Campaign. We achieved median H-band contrasts of 12.4 mag at 0.5" and 14.1 mag at 1" separation. Follow-up observations of the 66 candidates with projected separation 5MJup planet beyond 80 AU, and 3MJup planet outside of 40 AU, based on hot-start evolutionary models. We model the population of directly-imaged planets as d^2N/dMda ~ m^alpha a^beta, where m is planet mass and a is orbital semi-major axis (with a maximum value of amax). We find that beta 1.7. Likewise, we find that beta 3MJup planet beyond 10 AU, and beta 40 AU and planet masses > 3 MJup do not carve the central holes in these disks.

Wahhaj, Zahed; Nielsen, Eric L; Biller, Beth A; Hayward, Thomas L; Close, Laird M; Males, Jared R; Skemer, Andrew; Ftaclas, Christ; Chun, Mark; Thatte, Niranjan; Tecza, Matthias; Shkolnik, Evgenya L; Kuchner, Marc; Reid, I Neill; Pino, Elisabete M de Gouveia Dal; Alencar, Silvia H P; Gregorio-Hetem, Jane; Boss, Alan; Toomey, Douglas N C Lin Douglas W
2013-01-01

468

Optimistic Active Messages: Structuring Systems for High-Performance Communication

  CiteSeer

Summary: Recent networks and network interfaces promise remarkable communication performance with very little overhead, but current software structures impose substantial overhead that prevents applications from achieving the benefits of these new architectures. We propose a new software structure that eliminates much of the overhead while preserving the ease of programming of current systems. Our architecture relies on the compiler to bridge the gap between high-level application programs and low-level communication primitives. The compiler incorporates application code into message handlers using a new runtime mechanism called optimistic active messages. This work was supported in part by the Advanced Research Projects Agency under contracts N00014-91J -1698 and DABT63-93-C-008, by the National Science Foundation under contract MIP-9012773, by an NSF Presidential Young Investigator Award, by IBM, AT&T, and Digital Equipment Corp., by Project Scout under ARPA contract MDA972-92-J-1032, by a...

Frans Kaashoek; William E. Weihl; Deborah A. Wallach; Wilson C. Hsieh; Kirk L. Johnson
1994-01-01

469

Spin-dipole strengths and tensor correlation effects for ${}^{208}{\\rm Pb}(p,n)$ at 295 MeV

  Nuclear Experiment (arXiv)

Summary: We performed the multipole decomposition analysis (MDA) for the ${}^{208}{\\rm Pb}(p,n)$ data in order to obtain the spin-dipole (SD) strengths separated into each $\\Delta J^{\\pi}$ contribution $dB({\\rm SD}_{\\Delta J^{\\pi}};\\omega)/d\\omega$. The random phase approximation (RPA calculations reproduce the total SD strength reasonably well, whereas some discrepancies are found for separated SD strength. The centroids of the resonances are slightly lower and higher than the theoretical predictions for $1^-$ and $2^-$, respectively. These softening and hardening effects observed in $1^-$ and $2^-$ distributions would be due to the tensor correlation effects not included in the present RPA calculations.

T. Wakasa for the RCNP-E57; E59 collaborations
2010-04-29

470

Transforming Growth Factor ß\\Induces Cachexia and Systemic Fibrosis without an Antitumor Effect in Nude Mice

  CiteSeer

Summary: up by liver, spleen, lungs, kidneys, and tumor tissue but not by the brain. At doses exceeding 2 jig/day, TGF-,01 induced a generalized interstitial fibrosis and a cachexia, which was not mediated by elevated serum levels of tumor necrosis factor a as determined by Western blot analysis and enzyme-linked immunosorbent assay. A total of 200,000 cells of the estrogen receptor-negative human breast cancer line MDA-MB-231, which had been shown to be maximally growth inhibited in vitro by 40 pM TGF-/31 and to have high-affinity receptors (9, 11, 12), were injected into the mammary fat pad of each nude mouse. The duration of treatment was 16 days with ten animals in the control group and five animals in the treated groups. The dose ranged from 1 to 4 ^g per animal daily. The treatment was started 24 h after the injection of the tumor cells. Tumor

Gerhard Zugmaier; Soonmyoung Paik; George Wilding; Et Al; Contact The Aacr Publications; Gerhard Zugmaier; Soonmyoung Paik; George Wilding; Cornelius Knabbe; Ruth Lupu; Bernd Deschauer; Susan Simpson; Robert B. Dickson

471

Streptozotocin-Induced Diabetic Wistar-Kyoto Rats and Spontaneously Hypertensive Rats: Effects of Antioxidant (Honey) Treatment

  CiteSeer

Summary: Abstract: Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). Diabetic WKY and SHR were randomized into four groups and received distilled water (0.5 mL) and honey (1.0 g/kg) orally once daily for three weeks. Control SHR had reduced malondialdehyde (MDA) and increased systolic blood pressure (SBP), catalase (CAT) activity, and total antioxidant status (TAS). SBP, activities of glutathione peroxidase (GPx) and glutathione reductase (GR) were elevated while TAS was reduced in diabetic WKY. In contrast, SBP, TAS, activities ofInt. J. Mol. Sci. 2011, 12 1889

Omotayo O. Erejuwa; Siti A. Sulaiman; Mohd Suhaimi; Ab Wahab; Kuttulebbai N. S. Sirajudeen; Md Salzihan; Md Salleh; Sunil Gurtu
2011-01-01

472

Improving Web Design Methods with Architecture Modeling

  CiteSeer

Summary: Abstract. Many approaches have been developed for modeling the functional aspects of Web applications, but there is a lack of a modeling language for their architectural concerns. This paper proposes such a modeling language defined as a UML 2.0 profile, which allows the specification of domain-specific models for the architectural view of Web applications. The profile is part of the Web Software Architecture (WebSA) approach, which follows the Model Driven Architecture (MDA) principles. The modeling elements proposed for each WebSA model (subsystem, configuration and integration models) are both represented graphically and formalized by means of the profile and the metamodel, respectively. In this article we will focus on the Configuration model and how it is used to model the well-known Petstore example. 1


2005-01-01

473

pathways to improve cancer therapy

  CiteSeer

Summary: Signaling pathways play critical roles in cancer initiating cell (CIC) growth, differentiation, drug resistance and sensitivity to various therapeutic approaches. This presentation will discuss the key roles that the PI3K/ PTEN/Akt/mTOR/Gsk-3b pathway plays in therapeutic sensitivity of breast cancer. We isolated CIC from three different breast cancer cell lines (MCF-7, T47D and MDA-MB-231) by culture in doxorubicin followed by selection of non-adherent cells and FACS sorting with anti-CD44 and CD24 Abs. Breast CICs displayed increased drug resistance, mammosphere formation capacity and activated Akt expression than parental cells. The effects of the PI3K/PTEN/Akt/mTOR/Gsk-3b pathway on the CIC formation, and drug/hormonal resistance were further examined by the introduction of activated

James A. Mccubrey; Melissa L. Sokolosky; Kristin M. Stadelman; Michele Lehair; Alberto M. Martelli; Richard A. Franklin; Linda S. Steelman

474

Lipid Peroxidation Is another Potential Mechanism besides Pore-Formation Underlying Hemolysis of Tentacle Extract from the Jellyfish Cyanea capillata

  CiteSeer

Summary: Abstract: This study was performed to explore other potential mechanisms underlying hemolysis in addition to pore-formation of tentacle extract (TE) from the jellyfish Cyanea capillata. A dose-dependent increase of hemolysis was observed in rat erythrocyte suspensions and the hemolytic activity of TE was enhanced in the presence of Ca 2+, which was attenuated by Ca 2+ channel blockers (Diltiazem, Verapamil and Nifedipine). Direct intracellular Ca 2+ increase was observed after TE treatment by confocal laser scanning microscopy, and the Ca 2+ increase could be depressed by Diltiazem. The osmotic protectant polyethylenglycol (PEG) significantly blocked hemolysis with a molecular mass exceeding 4000 Da. These results support a pore-forming mechanism of TE in the erythrocyte membrane, which is consistent with previous studies by us and other groups. The concentration of malondialdehyde (MDA), an important marker of lipid peroxidation, increased dose-dependently in rat erythrocytes after TE treatment, while in vitro hemolysisMar. Drugs 2013, 11 68

Tao Wang; Xiao-juan Wen; Xiao-bin Mei; Qian-qian Wang; Qian He; Jie-min Zheng; Jie Zhao; Liang Xiao; Li-ming Zhang
2013-01-01

475

Avoiding another Green Elephant - A Proposal for the Next Generation HLA based on the Model Driven Architecture

  CERN Preprints

Summary: When looking through the proceedings of the recent Simulation Interoperability Workshops, a lot of papers - some of them even awarded by the committee - are dealing with alternative concepts outside or beyond the High Level Architecture (HLA): Web Services, the extensible Markup Language (XML), Java Beans, Simple Object Access Protocol (SOAP), etc. Similarly, requirements driven by interoperability issues have resulted in the need to use meta modeling, adaptive models, and common repositories. The use of the Unified Modeling Language (UML) as a model description language is also rapidly becoming a standard. All these concepts have relations to the HLA, but they are not part of it. There seems to be the danger that HLA is overrun by respective developments of the free market and will become irrelevant finally. ... This paper introduces the MDA concept and shows, how the HLA can be integrated to become a standard stub for simulation applications of legacy systems, systems under development, and systems of the f...

Tolk, Andreas
2010-01-01

476

A model-driven approach for composing SAWSDL semantic Web services

  CERN Preprints

Summary: Composing Web services is a convenient means of dealing with complex requests. However, the number of Web services on the Internet is increasing. This explains the growing interest in composing Web services automatically. Nevertheless, the Web services' semantics is necessary for any dynamic composition process. In this article, we present an MDA approach to develop and compose SAWSDL semantic Web services. To model Web services, we use a UML profile which is independent of the description standards. The SAWSDL interface files are generated by using transformation rules. To model the behavior of a composite Web service and generate its executable BPEL file, we use the BPMN notation in a platform of modeling and implementing business process. The main contribution of this work is the easy and extensible solution to a model-driven development of the semantic atomic and composite Web services.

Belouadha, Fatima-Zahra; Roudies, Ounsa
2010-01-01

477

Printed In U S.A Parental Recreational Drug Use and Risk for Neural Tube Defects

  CiteSeer

Summary: The authors investigated whether maternal or paternal periconceptional use of recreational drugs increased the nsk of having neural tube defect (NTD)-affected pregnancies using a population-based case-control study of fetuses and liveborn infants with NTDs among 1989-1991 California births. Face-to-face interviews were conducted with mothers of 538 (88 % of eligible) NTD cases and 539 (88%) nonmatformed controls, usually within 5 months of delivery. Periconceptional maternal use of cocaine (odds ratio (OR) = 0.74, 95 % confidence interval (Cl) 0.40-1.4), amphetamines/speed (OR = 0.68, 95 % Cl 0.39-1.2), or marijuana (OR = 0.64, 95 % Cl 0.43-0.95) or preconceptional use of alcohol as <1 drink/day (OR = 0.80, 95 % Cl 0.62-1.0) or ^ 1 dnnk/day (OR = 0.69, 95 % Cl 0.42-1.2) or of cigarettes as <1 pack/day (OR = 0.90, 95 % Cl 0.65-1.2) or &1 pack/day (OR = 0.59, 95 % Cl 0.36-0.96) did not increase the risk for delivering NTD-affected offspring. Risks were not substantially altered after adjustment for maternal age, race/ethnicity, vitamin use, education, and household income. Increased NTD risk was also not generally associated with patema) drug use. The authors could not discern whether the decreased risks observed for these maternal exposures reflected a true association or were due to reporting bias, a disproportionate number of drug-exposed NTD cases among spontaneous abortuses that could not be ascertained, or some other bias. Am J Epidemiol 1996;144:1155-60. abnormalities; anencephaly; etiology; pregnancy; spina bifida cystica; teratogens

Gary M. Shaw; Ellen M. Velie; Kimberly B. Morl

478

ssue 1 ADVISORY Breaking News for the Treatment Field Substance Abuse Treatment

  CiteSeer

Summary: What are inhalants? Inhalants are breathable chemical vapors or gases that produce psychoactive (mind-altering) effects when abused or misused. These include volatile organic solvents, fuel gases, nitrites, and anesthetic gases. They do not include inhaled medicinal drugs that are taken as prescribed. Once commonly referred to as “glue sniffing, ” inhalant abuse now includes a broad range of volatile solvents and gas products (e.g., model airplane glue, paint thinner, gasoline, and nail polish remover), aerosols (e.g., nonstick cooking spray and hair spray), anesthetics (e.g., nitrous oxide or “laughing gas ” and ether), and nitrites (e.g., amyl, butyl, and isobutyl nitrites, often marketed as “poppers ” or room odorizers). (Other powdered drugs, such as heroin, cocaine, and methamphetamine, can be inhaled but are not considered inhalants.) Although the chemicals involved and their effects vary, the route of administration is the common factor. What are the most common modes of administration? Inhalants are abused either by “sniffing ” through the nose or inhaling fumes through the open mouth (“huffing”) much like a smoker inhales cigarette smoke. Usually the open tube of glue, nail polish, or marker is placed close to the nose and the fumes are inhaled. People who abuse inhalants may also spray the substance into a plastic or paper bag and huff that way (“bagging”) or even place the bag over the entire head. Often a product will be poured or sprayed on a piece of cloth, a rag, a towel, or a shirt sleeve or into a soda can and inhaled in that manner. Another method is to paint the fingernails with a product such as correction fluid and inhale the substance from the nails. Sometimes an aerosol substance is sprayed directly into the mouth. Substances also can be placed into alternative containers (e.g., balloon filled with nitrous oxide) or heated and then inhaled (Synergies 2002). Who is likely to abuse inhalants? Contrary to popular perception, people who abuse inhalants are found throughout the population and no one group can be categorized as “inhalant abusers. ” In 2001, more than 18.2 million Americans reported ever having used an inhalant, and 141,000 were estimated to need treatment because they were dependent on or abused inhalants. According to the 2001 National

unknown authors
2003-01-01

479

Metformin, and Their Combinations in the Kidneys of Streptozotocin-Induced Diabetic Rats

  CiteSeer

Summary: Abstract: Hyperglycemia-induced increase in oxidative stress is implicated in diabetic complications. This study investigated the effect of metformin and/or glibenclamide in combination with honey on antioxidant enzymes and oxidative stress markers in the kidneys of streptozotocin (60 mg/kg; intraperitoneal)-induced diabetic rats. Diabetic rats were randomized into eight groups of five to seven rats and received distilled water (0.5 mL); honey (1.0 g/kg); metformin (100 mg/kg); metformin (100 mg/kg) and honey (1.0 g/kg); glibenclamide (0.6 mg/kg); glibenclamide (0.6 mg/kg) and honey (1.0 g/kg); metformin (100 mg/kg) and glibenclamide (0.6 mg/kg); or metformin (100 mg/kg), glibenclamide (0.6 mg/kg) and honey (1.0 g/kg) orally once daily for four weeks. Malondialdehyde (MDA) levels, glutathione peroxidase (GPx) and superoxide dismutase


2011-01-01

480

1 Results from Prior NSF Support

  CiteSeer

Summary: most recent of which was MDA904-00-1-0060. During the funded period (from 1995 to the present), the PI wrote or co-wrote seventeen published articles on the funded topics. Much of the PI’s work (funded through the Statistics and Probability subdivision within the Division of Mathematical Sciences) was probabilistic in nature, originating from the PI’s desire to understand the behavior of random tilings. The articles “Exact sampling with coupled Markov chains and applications to statistical mechanics ” (with David Wilson, 1996), “Generating random elements of a finite distributive lattice ” (1997), “How to get a perfectly random sample from a generic Markov chain and generate a random spanning tree of a directed graph ” (with David Wilson, 1998), and “Coupling from the past: a user’s guide ” (with David Wilson, 1998) developed and promulgated a general approach to the random generation of combinatorial objects such as tilings, which initiated a (still ongoing) flurry of activity by many researchers in the field of Markov Chain Monte Carlo (the new fashion of “exact sampling ” or “perfect sampling”, spearheaded by David Wilson; see

unknown authors

481

White Dwarf Mass Distribution in the SDSS

  Astrophysics (arXiv)

Summary: We determined masses for the 7167 DA and 507 DB white dwarf stars classified as single and non-magnetic in data release four of the Sloan Digital Sky Survey (SDSS). We obtained revised Teff and log g determinations for the most massive stars by fitting the SDSS optical spectra with a synthetic spectra grid derived from model atmospheres extending to log g=10.0. We also calculate radii from evolutionary models and create volume-corrected mass distributions for our DA and DB samples. The mean mass for the DA stars brighter than g=19 and hotter than Teff=12000K is M(DA)= 0.593+/-0.016M(Sun). For the 150 DBs brighter than g=19 and hotter than Teff=16000K, we find M(DB)=0.711+/-0.009 M(Sun). It appears the mean mass for DB white dwarf stars may be significantly larger than that for DAs. We also report the highest mass white dwarf stars ever found, up to 1.33 M(Sun).

S. O. Kepler; S. J. Kleinman; A. Nitta; D. Koester; B. G. Castanheira; O. Giovannini; A. F. M. Costa; L. Althaus
2007-01-17

482

A Report on Multilinear PCA Plus Multilinear LDA to Deal with Tensorial Data: Visual Classification as An Example

  CERN Preprints

Summary: In practical applications, we often have to deal with high order data, such as a grayscale image and a video sequence are intrinsically 2nd-order tensor and 3rd-order tensor, respectively. For doing clustering or classification of these high order data, it is a conventional way to vectorize these data before hand, as PCA or FDA does, which often induce the curse of dimensionality problem. For this reason, experts have developed many methods to deal with the tensorial data, such as multilinear PCA, multilinear LDA, and so on. In this paper, we still address the problem of high order data representation and recognition, and propose to study the result of merging multilinear PCA and multilinear LDA into one scenario, we name it \\textbf{GDA} for the abbreviation of Generalized Discriminant Analysis. To evaluate GDA, we perform a series of experiments, and the experimental results demonstrate our GDA outperforms a selection of competing methods such (2D)$^2$PCA, (2D)$^2$LDA, and MDA.

Kong, Shu
2012-01-01

483

Biological Sciences MUSHROOM POLYSACCHARIDE PROTECTS RADIATION INDUCED INTESTINAL DAMAGE IN MICE

  CiteSeer

Summary: The in vivo radioprotective effect of a polysaccharide (PS) isolated from the mushroom Ganoderma lucidum, against radiation (RT) induced intestinal damage was investigated. Young adult swiss albino mice were whole body exposed to gamma radiation. PS was administered orally (10 mg/kg body wt and 20 mg/kg body wt) 5 min after 4 Gy exposure. The radioprotective effect of PS was compared with that of clinically used radioprotective drug amifostine (WR- 2721), at 300 mg/kg body wt administered intraperitoneally, 30 min before irradiation. PS is not toxic at the radioprotective dose. Damage to the jejunum was observed in histopathological studies after radiation exposure. Administration of PS and amifostine offered protection against the intestinal damage. The level of GSH (reduced glutathione) in the jejunal mucosa was decreased after irradiation exposure. The depleted level of GSH in jejuna mucosa was restored significantly by polysaccharide and amifostine administration. Similarly serum MDA level was maintained normal by PS and Amifostine administration compared to radiation alone treated group. PS seems to have potential for use in protection against planned and unplanned radiation exposures. PS can be developed to an effective natural radioprotector without any side effects, after further studies.

Thulasig. Pillai

484

Whole body counter surveys of Miharu-town school children for four consecutive years after the Fukushima NPP accident

  CERN Preprints

Summary: Comprehensive whole-body counter surveys of Miharu town school children have been conducted for four consecutive years, in 2011-2014. This represents the only long-term sampling-bias-free study of its type conducted after the Fukushima Dai-ichi accident. For the first time in 2014, a new device called the Babyscan, which has a low $^{134/137}$Cs MDA of $< 50$ Bq/body, was used to screen the children shorter than 130 cm. No child in this group was found to have detectable level of radiocesium. Using the MDAs, upper limits of daily intake of radiocesium were estimated for each child. For those screened with the Babyscan, the upper intake limits were found to be <1 Bq/day for $^{137}$Cs. Analysis of a questionnaire filled out by the children's parents regarding their food and water consumption shows that the majority of Miharu children regularly consume local and/or home-grown rice and vegetables. This however does not increase the body burden.

Hayano, Ryugo S; Miyazaki, Makoto; Satou, Hideo; Sato, Katsumi; Masaki, Shin; Sakuma, Yu
2015-01-01

485

Original Investigation Melatonin in fibromyalgia doi: 10.5455/medscience.2012.01.8042 Adjuvant Use of Melatonin with Fluoxetine for Management of

  CiteSeer

Summary: Conflict of Interests: The authors declare that there is no conflict of interests. Fibromyalgia (FMS) is a chronic musculoskeletal disorder characterized by generalized muscular pain and tenderness at specific anatomical sites. Although melatonin was effective in treating the pain associated with this syndrome, no defined clinical evidence supports this claim. The present study was designed to evaluate the clinical significance of using melatonin, alone or in combination with fluoxetine in FMS. A double-blind clinical study was conducted on 45 patients with FMS randomized into 4 groups; group A, treated with fluoxetine 20mg/day alone; group B, treated with melatonin 5mg alone; group C, treated with combination of fluoxetine 20 mg+3 mg melatonin; group D treated with combination of fluoxetine 20 mg+5 mg melatonin. Both fluoxetine and melatonin were given once daily in the morning and night time respectively for 8 weeks. Each patient clinically evaluated using Fibromyalgia Impact Questionnaire (FIQ). Serum levels of serotonin, malondialehyde and nitric oxide were also evaluated. Using melatonin (3 and 5mg/day) in combination with 20mg/day fluoxetine significantly decreased total FIQ score values; the combination therapy significantly decreased serum serotonin level associated with reduction in the oxidative stress parameters (MDA and NO). In conclusion, adjuvant use of melatonin with fluoxetine improves the biochemical and clinical parameters of FMS patients.


486

RESEARCH Open Access Insecticide resistance in Culex quinquefasciatus from Zanzibar: implications for vector control programmes

  CiteSeer

Summary: Background: Zanzibar has a long history of lymphatic filariasis (LF) caused by the filarial parasite Wuchereria bancrofti, and transmitted by the mosquito Culex quinquefasciatus Say. The LF Programme in Zanzibar has successfully implemented mass drug administration (MDA) to interrupt transmission, and is now in the elimination phase. Monitoring infections in mosquitoes, and assessing the potential role of interventions such as vector control, is important in case the disease re-emerges as a public health problem. Here, we examine Culex mosquito species from the two main islands to detect W. bancrofti infection and to determine levels of susceptibility to the insecticides used for vector control. Methods: Culex mosquitoes collected during routine catches in Vitongoji, Pemba Island, and Makadara, Unguja Island were tested for W. bancrofti infection using PCR. Insecticide bioassays on Culex mosquitoes were performed to determine susceptibility to permethrin, deltamethrin, lambda-cyhalothrin, DDT and bendiocarb. Additional synergism assays with piperonyl butoxide (PBO) were used for lambda-cyhalothrin. Pyrosequencing was used to determine the kdr genotype and sequencing of the mitochondrial cytochrome oxidase I (mtCOI) subunit performed to identify ambiguous Culex species. Results: None of the wild-caught Culex mosquitoes analysed were found to be positive for W. bancrofti. High

Christopher M Jones; Camille Machin; Khalfan Mohammed; Silas Majambere; Abdullah S Ali; Bakari O Khatib; Juma Mcha; Hilary Ranson; Louise A Kelly-hope

487

A Comparative Study of Photo-oxidation on mesoporous vanadium–titanium

  CiteSeer

Summary: oxide catalysts with the application of ethanol Ar p a na S wa r a j M. S c Indu s t r ia l C h e m i s t r y J a mia Ha mda r d Univer s it y, D ehli Photo-oxidation with the application of ethanol was investigated over mesoporous, amorphous V + TiO2 and V + TiO2(anatase) catalysts. Mesoporous V + TiO2 generally exhibited faster photo-oxidation rates than V + TiO2(anatase) catalysts did Under the UV + visible light,. V IV doping directed preferable formation of acetic acid rather than predominant acetaldehyde formation. Under the visible light only, mesoporous V IV –TiO2 catalyst exhibited best reactivity among all V + TiO2 catalysts. Ethanol dehydration reaction was preferred. Initial quicker water evolution may suggest greater oxidation capability compared to V + TiO2(anatase) catalysts.A comparative studies of the reaction done in the past is revived and comparative consequences are discussed in this work.

unknown authors

488

Efficient Implementation of Capon and APES for Spectral Estimation

  CiteSeer

Summary: Both the Capon and APES estimators can be shown to belong to the class of matched-filterbank spectral estimators and can be used to obtain complex spectral estimates that have more narrow spectral peaks and lower sidelobe levels than the FFT methods. It can also be shown that APES has better statistical performance than Capon. In this paper, we address the issue of how to efficiently implement Capon and APES for spectral estimation. IEEE Transactions on Aerospace and Electronic Systems 1 Submitted August 1997 Revised December 1997 This work was supported in part by the Office of Naval Research Grant N00014-96-0817, the National Science Foundation Grant MIP-9457388, and the Advanced Research Project Agency Grant MDA-972-93-1-0015. y The authors are with the Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA. 1 Please address all correspondence to: Dr. Jian Li, Department of Electrical and Computer Engineering, P. O. Box 116130, U...

Zheng-She Liu Hongbin; Zheng-she Liu; Hongbin Li; Jian Li
1998-01-01

489

Matched-Filter Bank Interpretation of Some Spectral Estimators

  CiteSeer

Summary: We make use of a matched-filter bank (MAFI) approach to derive spectral estimators for stationary signals with mixed spectra. We show that the Capon spectral estimator as well as the more recently introduced APES (amplitude and phase estimation) method are members of the MAFI class. A seemingly new MAFI-based spectral estimator is shown to reduce to APES as well. The MAFI interpretation of Capon and APES, along with some additional analysis, provides further insights into the properties of and the relationship between these two spectral estimation methods. This work was supported in part by the Senior Individual Grant Programme of the Swedish Foundation for Strategic Research, the Swedish National Board for Technical Development (NUTEK), the NSF Grant MIP-9457388 and the ARPA Grant MDA-972-93-1-0015. y Petre Stoica and Andreas Jakobsson are with the Systems and Control Group, Department of Technology, Uppsala University, P.O. Box 27, S-751 03 Uppsala, Sweden. z Jian Li is with th...

Petre Stoica; Andreas Jakobsson; Jian Li

490

DRAFT WISCONSIN MERCURY SOURCEBOOK: DENTISTS 249 MERCURY USE: DENTISTS

  CiteSeer

Summary: Dental amalgam is an alloy that results from the trituration of powdered silver, tin and copper which hardens quickly to a solid phase. Dental amalgams have been used as the main restorative in teeth for more than 150 years; it is a popular restorative material because it can be easily manipulated and is relatively inexpensive. Amalgam wastes are generated from amalgam abrasion, from the placement or replacement of fillings, and from cremation. The Western Lake Superior Sanitary District has estimated that dentists emit 0.1 grams of mercury per day per dentist. The approximate 1,650 dental offices in the metropolitan Seattle, Washington area contribute an estimated 14 percent of the mercury in that system. San Francisco has estimated that 12 percent of the mercury contributed to that city’s system comes from dental offices. (directly from the concern over mercury and wastewater, journal of MDA) It has been estimated that approximately 4 percent of the mercury entering the Lake Superior

unknown authors

491

Bioremediation of Polluted Diets with Industrial Wastewater Using Marine and Earth Fungi: Molecular Genetic, Biochemical and Histopathological Studies in Mice

  CiteSeer

Summary: Abstract: Samples of wastewater or effluent discharge were collected from sugarcane begass cellulose wood-mill. Phenol compounds were the main pollutants of the wastewater. The discharge samples were used for the preparation of biological diets. Five experimental groups, of 10 mice each were used. The first group was fed a normal diet (N diet) and used as a control. The second group was fed the same normal diet mixed with manufactory discharge (ND diet). The third, fourth and fifth groups were fed ND diet treated with marine (Asperigllus oryzae) fungus (NDA diet), earth (Trichoderma reesei) fungus (NDT diet) and mixture of marine and earth fungi (NDAT diet), respectively. The animals of the five groups were fed the corresponding mentioned diets for three weeks. After that, mice were inspected for gene expression of mdr1b and CYP1A2 genes, comet assay of DNA, biochemical parameters and histopathological examination. The administration of ND diet alone induced over expression levels of mdr1b and CYP1A2 genes, significantly (P<0.05) higher DNA damage, elevation of ALT, AST, uric acid, creatinine and MDA levels and significant (P<0.05) augmentation of haematological parameters (TEC, TLC and Hb(g/d1)) as well as severe damage in liver and kidney tissues. However, the use of NDA or NDT or NDAT bioremediation diets diminished most of the deleterious effects of ND diet alone and significantly (P<0.05) ameliorated all above measurements of molecular genetics, biochemistry and histopathology. Moreover, the ability to induce the improvements of such measurements

Mariam G. Eshak; M. M. Hassanane; Ibrahim M. Farag; M. Fadel

492

Business Service Modeling for the Service-Oriented

  CiteSeer

Summary: Service-oriented architectures are the upcoming business standard for realizing enterprise information systems, thus creating a need for analysis and design methods that are truly service-oriented. Most research on this topic so far takes a strict software engineering perspective. For a proper alignment between the business and the IT, a service perspective at the business level is needed as well. Although few researchers realized the importance of business thinking at service design, notation for service design is still lacking. Using an MDA approach, [1] introduces a new business service and resource modeling language- BSRM based on the Resource-Event-Agent (REA) business ontology. The constructs of the BSRM language and their relationships are grounded in a meta-model which provides comprehensive specification using UML notation. Following the REA, we defined the service as a specialization of economic resource in the meta-model. As the resources are first class citizen of REA, BSRM gives a better insight to the value co-creation which is the main focus of services. Further, we distinguish two service specializations: exchange service and conversion service, corresponding to the two basic REA dualities. Each of them corresponds to a group of decrement and increment economic events in REA. The service classification model developed in [2], categorizes services into several categories. Among these service categories enhancing services and the sub-services which have part of relationship to the core services are special types of services that play a major role in service modeling at business level. These service categories correspond to different roles of the service type in our model. The concept of enhancing services which adds value to the any other service, is introduced as another service category in our model. Considering the situation where core-service realization involves multiple value activities and it makes sense to view these value activities as independent services that are shared by different contexts, we

Jeewanie Jayasinghe Arachchige; Hans Weig; Manfred Jeusfeld

493

Summary on m_{c,b}(m_{c,b}) and precise f_{D_(s),B_(s)} from heavy-light QCD spectral sum rules

  HEP - Lattice (arXiv)

Summary: We summarize recent results obtained in [1] on the running m_{c,b}(m_{c,b}) in the MS scheme and f_{D_(s), B_(s)} using QCD spectral sum rules (QSSR) known to N2LO PT series, including all dimension-six NP condensate contributions in the full QCD theory, an estimate of the N3LO terms based on the geomteric growth of the PT series and using the most recent values of the QCD input parameters given in Table [1]. The study of the effects of the subtraction scale \\mu on "different QSSR data" and the use (for the first time) of the Renormalization Group Invariant (RGI) scale independent quark masses in the analysis are emphasized. The estimates [rigourous model-independent upper bounds] reported in Table 2: f_D/f_\\pi=1.56(5)[< 1.68(1)], f_B/f_\\pi=1.58(5)[< 1.80(3)] and f_{D_s}/f_K= 1.58(4) [< 1.63(1)], f_{B_s}/f_K=1.50(3)[< 1.61(3.5)], improve previous QSSR estimates. The remarkable agreements with some of the experimental data on f_{D,D_s} and with lattice simulations within dynamical quarks confirm both the success of the QSSR semi-approximate approach based on the OPE in terms of the quark and gluon condensates and of the Minimal Duality Ansatz (MDA) for parametrizing the hadronic spectral function which we have tested from the complete data of the J/\\psi and \\Upsilon systems. The running quark masses m_c({m_c})=1286(66) MeV and m_b({m_b})= 4236(69) MeV from M_{D,B} are in good agreement though less accurate than the ones from recent J/\\psi and \\Upsilon sum rules.

Stephan Narison
2012-09-13

494

Novel Ganglioside Antigen Identified by B Cells in Human Medullary Breast Carcinomas: The Proof of Principle Concerning the Tumor-Infiltrating

  CiteSeer

Summary: The potential tumor-recognizing capacity of B cells infiltrating human breast carcinoma is an important aspect of breast cancer biology. As an experimental system, we used human medullary breast carcinoma because of its heavy B lymphocytic infiltration paralleled to a relatively better prognosis. Ig-rearranged V region V H-J H,V?-J?, and V?-J ? genes, amplified by RT-PCR of the infiltrating B cells, were cloned, sequenced, and subjected to a comparative DNA analysis. A combinatorial single-chain variable fragment Ab minilibrary was constructed out of randomly selected V H and V ? clones and tested for binding activity. Our data analysis revealed that some of the V H-J H,V?-J?, and V?-J ? region sequences were being assigned to clusters with oligoclonal predominance, while other characteristics of the Ab repertoire were defined also. A tumor-restricted binder clone could be selected out of the single-chain variable fragment ? minilibrary tested against membrane fractions of primary breast tumor cells and tumor cell lines, the V H of which proved to be the overexpressed V H3-1 cluster. The specific binding was confirmed by FACS analysis with primary breast carcinoma cells and MDA-MB 231 cell line. ELISA and thin layer chromatography dot-blot experiments showed this target Ag to be a ganglioside D3 (GD3). Our results are a proof of principle about the capacity of B cells infiltrating breast carcinomas to reveal key cancer-related Ags, such as the GD3. GD3-specific Abs may influence tumor cell progression and could be used for further development of diagnostic and/or therapeutic purposes. The Journal of Immunology, 2005, 175: 2278–2285. Recombinant Abs and their fragments represent now a

B Lymphocytes; Beatrix Kotlan; Peter Simsa; Jean-luc Teillaud; Wolf Herman Fridman; Jozsef Toth; Michael Mcknight; Mark C. Glassy

495

Deriving Dg Categories

  CiteSeer

Summary: We investigate the (unbounded) derived category of a differential Z-graded category (=DG category). As a first application, we deduce a 'triangulated analogue` (4.3) of a theorem of Freyd's [5, Ex. 5.3 H] and Gabriel's [6, Ch. V] characterizing module categories among abelian categories. After adapting some homological algebra we go on to prove a 'Morita theorem` (8.2) generalizing results of [19] and [20]. Finally, we develop a formalism for Koszul duality [1] in the context of DG augmented categories. Summary We give an account of the contents of this paper for the special case of DG algebras. Let k be a commutative ring and A a DG (k-)algebra, i.e. a Z-graded k-algebra A = a p2Z A p endowed with a differential d of degree 1 such that d(ab) = (da)b + (\\Gamma1) p a(db) for all a 2 A p , b 2 A. A DG (right) A-module is a Z-graded A-module M = ` p2Z M p endowed with a differential d of degree 1 such that d(ma) = (dm)a + (\\Gamma1) p m(da) for all m 2 M p , a 2 A. A morphism of DG A-modules is a homogeneous morphism of degree 0 of the underlying graded A-modules commuting with the differentials. The DG A-modules form an abelian category CA. A morphism f : M ! N of CA is null-homotopic if f = dr + rd for some homogeneous morphism r : M ! N of degree-1 of the underlying graded A-modules.

Bernhard Keller
1993-01-01

496

A fresh look into m_{c,b} and precise f_{D_(s),B_(s)} from heavy-light QCD spectral sum rules

  HEP - Experiment (arXiv)

Summary: Using recent values of the QCD (non-) perturbative parameters given in Table 1 and an estimate of the N3LO QCD perturbative contributions based on the geometric growth of the PT series, we re-use QCD spectral sum rules (QSSR) known to N2LO PT series and including all dimension-six NP condensate contributions in the full QCD theory, for improving the existing estimates of {m}_{c,b} and f_{D_(s)}, f_{B_(s)} from the open charm and beauty systems. We especially study the effects of the subtraction point on "different QSSR data" and use (for the first time) the Renormalization Group Invariant (RGI) scale independent quark masses in the analysis. The estimates [rigourous model-independent upper bounds within the SVZ framework] reported in Table 8: f_D/f_\\pi=1.56(5)[< 1.68(1)], f_B/f_\\pi=1.58(5)[< 1.80(3)] and f_{D_s}/f_K= 1.58(4) [< 1.63(1)], f_{B_s}/f_K=1.50(3)[< 1.61(3.5)], which improve previous QSSR estimates, are in perfect agreement (in values and precisions) with some of the experimental data on f_{D,D_s} and on recent lattice simulations within dynamical quarks. These remarkable agreements confirm both the success of the QSSR semi-approximate approach based on the OPE in terms of the quark and gluon condensates and of the Minimal Duality Ansatz (MDA) for parametrizing the hadronic spectral function which we have tested from the complete data of the J/\\psi and \\Upsilon systems. The values of the running quark masses m_c(m_c)=1286(66) MeV and m_b(m_b)= 4236(69) MeV from M_{D,B} are in good agreement though less accurate than the ones from recent J/\\psi and \\Upsilon sum rules.

Stephan Narison
2012-12-08

497

PG1115+166 - a long period DA+DB binary

  Astrophysics (arXiv)

Summary: We present spectra of the DAB white dwarf PG1115+166. Radial velocity measurements of the Balmer lines and the HeI6678 line show that this is a binary white dwarf with a period of 30.09d in which the Balmer lines move in anti-phase to the HeI line, i.e., PG1115+166 is a DA+DB binary. The minimum masses of the stars are M_DA=0.43+-0.15 solar masses and M_DB=0.52+-0.12 solar masses. The separation of the stars is about 45 solar radii which is much smaller than a typical AGB progenitor of a white dwarf, implying that there has been at least one common envelope phase in this binary. Indeed, it is possible that this binary may have suffered up to three mass transfer episodes - two associated with the red giant phase prior to the formation of each white dwarf and a third associated with the ``born-again'' red giant phase of the DB white dwarf. PG1115+166 has the longest orbital period of any post common envelope white dwarf - white dwarf binary found to date. Published models for the formation of white dwarf - white dwarf binaries do not predict any white dwarfs with the combination of long orbital period and high mass found in PG1115+166. We conclude that PG1115+166 is a key object for testing models of binary star evolution and it may also be a key object for our understanding of the formation of DB white dwarfs. We outline the observational tests which can be applied to scenarios for the formation of PG1115+166 and apply them to the simplest case of a single common envelope phase. This suggests that some part of the internal energy stored in the envelope of the AGB star, e.g., as ionized hydrogen, may have contributed to the ejection of the common envelope, but there are several unanswered questions concerning this simple scenario.

P. F. L. Maxted; M. R. Burleigh; T. R. Marsh; N. P. Bannister
2002-03-29

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