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Sample search results for: abd-fused anti-her2 affibody

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1 DOI: 10.1002/cmdc.200800122 HER-2-Targeted NanoparticleAffibody Bioconjugates for Cancer Therapy
 

Summary:  -scale production. The anti-HER-2 affibody (Z-HER2: 342 affibody) has shown high binding affinity (KD ~22 pm... delivery. To develop HER-2-targeted drug-encapsulated NPs, we con- jugated the anti-HER-2 affibody... lyophilization, confirming the ...

  

Source: Zhang, Liangfang - Department of Nanoengineering, University of California at San Diego

 

Collection: Materials Science

 
2 [99mTc(CO)3]+-Labeled anti-epidermal growth factor receptor (HER2) affibody ZHER2:342 with a hexa-histidine tag (H6) on the N-
 

Summary:  . Comparative in vivo evaluation of technetium and iodine labels on an anti-HER2 affibody for single... benefit from anti-HER2 antibody (Ab) therapy (e.g., for breast cancer), to determine the efficacy... of Abs against the anti-HER2 Abs), ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
3 [99mTc(CO)3]+-Labeled anti-epidermal growth factor receptor (HER2) affibody ZHER2:342 with a tri-(histidine-glutamate) peptide tag
 

Summary:  . Comparative in vivo evaluation of technetium and iodine labels on an anti-HER2 affibody for single... to screen for patients who would benefit from anti-HER2 antibody (Ab) therapy (e.g., for breast cancer... of Abs against the anti-HER2 Abs), ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
4 [99mTc(CO)3]+-Labeled anti-epidermal growth factor receptor (HER2) affibody ZHER2:342 with a hexa-histidine tag (H6) on the C-
 

Summary:  on an anti-HER2 affibody for single-photon imaging of HER2 expression in tumors. J Nucl Med 2006... benefit from anti-HER2 antibody (Ab) therapy (e.g., for breast cancer), to determine the efficacy... of Abs against the anti-HER2 Abs), ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
5 10.1517/14712590802181330 2008 Informa UK Ltd ISSN 1471-2598 1063 All rights reserved: reproduction in whole or in part not permitted
 

Summary:  of a bivalent anti-HER-2 affibody with potential for radionuclide-based diagnostics. Cancer Biother Radiopharm... . formulated anti-HER2 mAb-liposome conjugates to study tumor targeting [62]. In this study, targeted liposomes... greater efficacy. Park et al. studied ...

  

Source: Zhang, Liangfang - Department of Nanoengineering, University of California at San Diego

 

Collection: Materials Science

 
6 Royal Institute of Technology AlbaNova University Center
 

Summary:  .biotech.kth.se KTH School of Biotechnology Department of Molecular Biotechnology Affibody binding proteins. The small... -Åke Nygren (perake@biotech.kth.se) Specific targeting. Based on selected affibody proteins, reagents... centered around a novel class of affinity proteins termed affibody binding proteins (1). These proteins

  

Source: Kjellström, Hedvig - School of Computer Science and Communication, Royal Institute of Technology (KTH)

 

Collection: Computer Technologies and Information Sciences

 
7 Molten globules move into action Lynne Regan*
 

Summary:  on the surface of phage. These proteins are optimistically named ``affibodies.'' After several rounds... of selection, the affibody ``ZSPA-1'' was isolated and char- acterized, both alone and as a complex... with the wild-type Z domain. Interest- ingly, the affibody ZSPA-1 alone dis- played several features reminiscent

  

Source: Mochrie, Simon - Department of Applied Physics, Yale University; Regan, Lynne - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine ; Biotechnology ; Materials Science ; Physics

 
8 Synthesizing a Novel Chelating Model Ben Kasten, Paul Benny, Tanushree Ganguly, Adam Moore;
 

Summary:  molecules (affibodies, peptides, small molecules, etc.). This summer's research has produced a novel ligand

  

Source: Collins, Gary S. - Department of Physics and Astronomy, Washington State University

 

Collection: Physics

 
9 This journal is c The Royal Society of Chemistry 2011 Integr. Biol., 2011, 3, 603631 603 Cite this: Integr. Biol., 2011, 3, 603631
 

Summary:  be useful in urological cancer. 124 I-PET 124 I-antibody fragments, e.g. anti-HER2 antibodies and 124 I... -annexin V Anti-HER2 labelled diabody used to image HER2 + ve xenograft57 Longer half-life (100.3 h

  

Source: Selvin, Paul R. - Department of Physics, University of Illinois at Urbana-Champaign

 

Collection: Physics ; Materials Science

 
10 Vaccination anti-HER2: L'avenir du ciblage immunologique de Anti-HER2 vaccines: The HER2 immuno-targeting future?
 

Summary:  Vaccination anti-HER2: L'avenir du ciblage immunologique de HER2? Anti-HER2 vaccines: The HER2... 'hui démontrée d'une immunothérapie anti-HER2 à base de trastuzumab dans ces cancers, ont permis d... immunologique. Dans cette revue, nous discuterons les diverses ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
11 FINDINGS IN BRIEF S W E D I S H U N I V E R S I T Y O F A G R I C U L T U R A L S C I E N C E S
 

Summary:  studying the way in which an ar- tificial protein (Affibody) can neutralise the substance giving rise... to the disease. However,before a drug can be developed, the properties of theAffibody protein will have

  

Source: Sveriges Lantbruksuniversitet (Swedish University of Agricultural Sciences)

 

Collection: Multidisciplinary Databases and Resources

 
12 Journal of Innovative Optical Health Sciences Vol. 2, No. 4 (2009) 387396
 

Summary:  MNPs and free anti-HER2 antibody revealed that the antibody molecules bind to the MNPs predominantly... with anti- HER2 antibody to target HER2 antigen in human breast carcinomas. The Fc-directed specificity... MNPs and free anti-HER2 antibod- ...

  

Source: Oldenburg, Amy - Biomedical Research Imaging Center & Department of Physics and Astronomy, University of North Carolina at Chapel Hill

 

Collection: Physics ; Biology and Medicine

 
13 Molekulare Prsentationstechniken Phage Display
 

Summary:  Bindemoleküle Current Opinion in Structural Biology 2007, 17:481 Fab Fn3 Ankyrin Z-Domäne ,,Affibody" Lipocalin

  

Source: Müller, Kristian - Institut für Biologie III, Albert-Ludwigs-Universität Freiburg

 

Collection: Biotechnology ; Biology and Medicine

 
14 LU TP 03-14 June 25, 2003
 

Summary:  -idiotypic protein domains selected from protein A-based affibody libraries. Proteins 2002; 48: 454­462. [4] Wahlberg... ¨ard T. An affibody in complex with a target protein: Structure and coupled folding. Proc. Natl. Acad... by an in vitro evolved affibody. Proc. Natl. Acad. Sci. USA 2003; 100: 3191­3196. [7] Bai Y, Karimi A, ...

  

Source: Lunds Universitet, - Computational Biology and Biological Physics Group

 

Collection: Physics ; Biology and Medicine

 
15 GeneTherapy Using Adenovirus-Mediated Full-length Anti-HER-2 Antibody for HER-2 Overexpression Cancers
 

Summary:  GeneTherapy Using Adenovirus-Mediated Full-length Anti-HER-2 Antibody for HER-2 Overexpression... , adenovirus was chosen as expression vector for its many advantages (25­28). Full-length anti-HER-2 antibody... encephalomyocarditis virus and under the control of mCMV promoter. Recombinant ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
16 Anti-HER2 vaccines: new prospects for breast cancer therapy Maha Zohra Ladjemi1
 

Summary:  1 Anti-HER2 vaccines: new prospects for breast cancer therapy Maha Zohra Ladjemi1 , William Jacot2... to the hypothesis that the generation of an anti-HER2 immune response should protect patients from HER2... -overexpressing tumor growth. Taken together with the clinical efficiency of trastuzumab-based ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
17 Cancer Immunol Immunother . Author manuscript Anti-HER2 vaccines: new prospects for breast cancer therapy
 

Summary:  Cancer Immunol Immunother . Author manuscript Page /1 18 Anti-HER2 vaccines: new prospects... so led to the hypothesis that the generation of an anti-HER2 immune response should protect patients... -based anti-HER2 passive immunotherapy these observations allowed to ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
18 In vivo therapeutic synergism of anti-EGFR and anti-HER2 monoclonal antibodies against pancreatic carcinomas
 

Summary:  1 In vivo therapeutic synergism of anti-EGFR and anti-HER2 monoclonal antibodies against pancreatic... -EGFR (matuzumab) and anti-HER2 (trastuzumab) mAbs either alone or in combination. The effect of the two m... with a decrease in EGFR and HER2 receptors phosphorylation Conclusions: ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
19 RESEARCH ARTICLE Open Access Vaccination with human anti-trastuzumab
 

Summary:  anti-HER2 Ab1' antibodies that can efficiently inhibit growth of SK-OV-3 cell tumors in nude mice... an anti-HER2 Ab1' immune response together with a scFv69-specific Th1 response with IL2 and IFN-g cytokine... , protects mice from developing HER2-positive mammary tumors by inducing both ...

  

Source: Ecole Polytechnique, Centre de mathématiques; Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Mathematics ; Physics

 
20 Original article Combined Cetuximab and Trastuzumab are superior to Gemcitabine in the
 

Summary:  a treatment-refractory cancer with a poor prognosis. Here, we compared anti-EGF receptor and anti-HER2... with either combined anti-EGFR (cetuximab) and anti-HER2 (trastuzumab), or gemcitabine and tumor growth were... in the malignant phenotype,8-11 we have recently demonstrated that the coinjection of ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics


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21 Combinaison d'anticorps anti-EGFR et anti-HER2 : un espoir dans le traitement du cancer du pancras
 

Summary:  1 Combinaison d'anticorps anti-EGFR et anti-HER2 : un espoir dans le traitement du cancer du... pancréas Combination of anti-EGFR and anti-HER2 antibodies : hope in pancreatic cancer treatment 1 Christel... anti-EGFR) et le trastuzumab (Ac anti- ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
22 Association d'anticorps anti-EGFR et anti-HER2 : Efficacit pr-clinique dans le traitement du cancer du pancras
 

Summary:  Association d'anticorps anti-EGFR et anti-HER2 : Efficacité pré-clinique dans le traitement du... -EGFR) ou le pertuzumab (anti-HER2). En oncologie, les associations thérapeutiques sont la règle car elles... étaient a priori exclus des thérapies anti-HER2. En ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
23 An overview of quantumquantum dotdot synthesis, applications
 

Summary:  ? Control AntiHER2 #12;Quantum dots ~2 - 6 nm #12;How are they made? #12;Synthesis Movie http

  

Source: Smalley, Richard E.- Departments of Chemistry & Physics, Rice University

 

Collection: Materials Science ; Chemistry

 
24 School of Life Sciences School of Engineering IBI Institute of Bioengineering / Institut de bioingnierie
 

Summary:  anti-Her2 antibodies as a model, that these engineered antibodies display novel pharmacological

  

Source: Guerraoui, Rachid - Faculté Informatique et Communications, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Computer Technologies and Information Sciences

 
25 Multiplexed Multicolor Raman Imaging of Live Cells with Isotopically Modified Single Walled Carbon Nanotubes
 

Summary:  12-SWNT, C13-SWNT, and C12/C13-SWNTs were conjugated to Herceptin (anti-Her2), Erbitux (anti-Her1... the isotope effect.16,17 We first incubated BT474 breast cancer cells (Her2+) with C12- SWNT-anti-Her2 for 2 h... , 13540­13541 #12;SWNT-anti-Her2, C13-SWNT-anti-Her1, ...

  

Source: Dai, Hongjie - Department of Chemistry, Stanford University

 

Collection: Chemistry

 
26 Negative Regulation of HER2 Signaling by the PEST-type Protein-tyrosine Phosphatase BDP1*
 

Summary:  of aberrant HER2 activity in breast cancer, the monoclonal anti-HER2 antibody Trastuzumab (Herceptin... protein was expressed in Escherichia coli, purified, and used to immunize rabbits. A monoclonal anti-HER2... antibody was used for immunoprecipitation and the poly- clonal ...

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine

 
27 Biotechnol. Appl. Biochem. (2002) 35, 91105 (Printed in Great Britain) 91 Genetic design for facilitated production and recovery of
 

Summary:  of host system depends on many Key words: affibody, affinity tag, fusion protein, in vitro refolding

  

Source: Lebendiker, Mario - Wolfson Centre for Applied Structural Biology, Hebrew University of Jerusalem

 

Collection: Biotechnology ; Biology and Medicine

 
28 Micelle-Like Architecture of the Monomer Ensemble of Alzheimer's Amyloid-Peptide in Aqueous Solution and
 

Summary:  ­40 bound to an affibody protein identified via phage display (PDB ID 2OTK).57 The protein is shown... determined "monomeric" structure of A1­40 bound to an "affibody" dimer (i.e., an artificial mutant protein... own, populates conformations compatible with those in the fibril model and bound to an affibody (Fig

  

Source: Caflisch, Amedeo - Department of Biochemistry, Universität Zürich

 

Collection: Biology and Medicine

 
29 BioMed Central Page 1 of 11
 

Summary:  Research article Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective... . Methods: The complex was constructed by covalently conjugating carboxylated SWNTs with anti-HER2 chicken... recently demonstrated the advantages of using ...

  

Source: Kirby, Brian J. - Sibley School of Mechanical and Aerospace Engineering, Cornell University

 

Collection: Chemistry ; Engineering

 
30 Mol Biosyst . Author manuscript Strong and oriented immobilization of single domain antibodies from
 

Summary:  ), scFv (single chain variable Fragment) but also aptamers and affibodies are arrayed on a support... . Renberg B , Nordin J , Merca A , Uhlen M . Affibody molecules in protein capture microarrays: evaluation

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
31 RESISTANCE TO TAMOXIFEN-INDUCED APOPTOSIS IS ASSOCIATED WITH DIRECT INTERACTION BETWEEN Her2/neu AND CELL MEMBRANE
 

Summary:  , MA), anti-RAR- (M-454, Santa Cruz), anti-Her2/neu (9G6, Santa Cruz) and anti-Bcl-2 (100, Santa Cruz... of antibodies of mouse anti-Her2/neu (9G6, Santa Cruz) and rabbit anti-ER- (H-184, Santa Cruz) were used... . The supernatant proteins (400 g) were incubated with anti- ...

  

Source: Lin, Chi-Hung - Institute of Immunology and Microbiology, National Yang-Ming University

 

Collection: Biology and Medicine

 
32 Strong and oriented immobilization of single domain antibodies from crude bacterial lysates for high-throughput compatible cost-effective
 

Summary:  such as Fab (Fragment Antigen Binding), scFv (single chain variable Fragment) but also aptamers and affibodies... ] Renberg, B., Nordin, J., Merca, A., Uhlen, M., et al., Affibody molecules in protein capture microarrays

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
33 1477-3627/03/$ see front matter 2003 Elsevier Science Ltd. All rights reserved. PII: S1477-3627(03)02383-3 World-wide genome projects have led to
 

Summary:  in [25]) and antibody mimetics, such as Protein A-based affibodies [26] or lipocalin-based anti- calins... -idiotypic protein domains selected from protein A-based affibody libraries. Proteins 48, 454­462 27 Skerra, A. (2001

  

Source: Konthur, Zoltán - Max-Planck-Institut für molekulare Genetik

 

Collection: Biology and Medicine

 
34 Self-Assembled Lipid Polymer Hybrid Nanoparticles: A Robust Drug Delivery
 

Summary:  when generaliz- ing this idea to protein-based targeting systems us- ing antibodies or affibodies

  

Source: Zhang, Liangfang - Department of Nanoengineering, University of California at San Diego

 

Collection: Materials Science

 
35 Optimal modulation frequencies for small-tissue imaging based on the equation of radiative transfer
 

Summary:  of Nuclear Medicine 48, 295-303 (2007). 13. F.Y. Nilsson and V. Tolmachev, "Affibody (R) molecules: New

  

Source: Hielscher, Andreas - Department of Biomedical Engineering, Columbia University

 

Collection: Engineering ; Biology and Medicine

 
36 2 0 0 8 A m e r i c A n c h e m i c A l S o c i e t y Before a biosensor can detect a molecule, it must concen-
 

Summary:  ) the affibody or igG-binding protein (1ZXh), (e) the Fab domain 1ZA3, and (f) the fibronectin domain Fn3

  

Source: Penner, Reginald M. - Department of Chemistry, University of California, Irvine; Weiss, Gregory A. - Department of Chemistry, University of California, Irvine

 

Collection: Chemistry ; Materials Science

 
37 MicroArrays and proteomics Arne Elofsson
 

Summary:  Expression proteomics ­ 2-D-gels + mass spectroscopy ­ Affibody based analysis Cell map proteomics

  

Source: Elofsson, Arne - Stockholm Bioinformatics Center, Stockholms Universitet

 

Collection: Biotechnology ; Biology and Medicine

 
38 Molecular Immunocomputing with Application to Alphabetical Pattern Recognition Mimics the Characterization of ABO Blood Type
 

Summary:  , and affibody display, have been developed to expedite the production of antibodies and/or antibody mimics (Haab

  

Source: Seoul National University, School of Computer Science and Engineering, Biointelligence Lab; Zhang, Byoung-Tak - School of Computer Science and Engineering, Seoul National University

 

Collection: Biology and Medicine ; Computer Technologies and Information Sciences

 
39 650 volume 28 number 7 july 2010 nature biotechnology With the broadening availability of tools
 

Summary:  or nanobodies) Protein scaffold Fibronectin Ankyrin repeat Armadillo repeat Lipocalin (anticalin) Affibody

  

Source: Konthur, Zoltán - Max-Planck-Institut für molekulare Genetik

 

Collection: Biology and Medicine

 
40 Vol. 40, No. 4 (2006) BioTechniques 423 Protein Microarrays
 

Summary:  RNA) display, and affibody display have been developed to expedite the production of antibodies with high

  

Source: Chen, Chien-Sheng - Institute of Systems Biology and Bioinformatics, National Central University

 

Collection: Biology and Medicine


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41 NATURE METHODS | VOL.4 NO.1 | JANUARY 2007 | 13 ProteomeBinders: planning a European resource of
 

Summary:  ,10 (Affibodies11,Anticalins12,designedAnkyrin repeat proteins13 and others), nucleic acid aptamers14, peptides

  

Source: Konthur, Zoltán - Max-Planck-Institut für molekulare Genetik; Krobitsch, Sylvia - Max-Planck-Institut für molekulare Genetik

 

Collection: Biology and Medicine

 
42 This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Protein Engineering Design and Selection following peer review. The definitive publisher-
 

Summary:  -CEA or anti-HER2 scFv or to the H60 murine ligand of NKG2D, respectively. We demonstrated the capacity... antibody with our anti-HER2 bifunctional protein an E:T ratio of 30:1 was used. After incubation for 4 h... ;trastuzumab antibody and anti-HER2 bifunctional ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
43 Protein Eng Des Sel. Author manuscript Redirecting NK cells mediated tumor cell lysis by a new recombinant
 

Summary:  of human IgG1 Fc" " " " fragments fused to an anti-CEA or anti-HER2 scFv or to the H60 murine ligand of NKG... of trastuzumab antibody with our anti-HER2 bifunctional protein an E:T ratio of 30:1 was used. After incubation... mAb used at 20 g/ml. In the experiment comparing trastuzumab antibody and ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
44 Subscriber access provided by UNIV OF MARYLAND COLL PARK The Journal of Physical Chemistry B is published by the American Chemical
 

Summary:  , the high free energy fibril-like N* conformations in the A monomer can be stabilized by a affibody protein... with affibody has been determined by NMR50 adopts a hairpin-like conformation. A similar hairpin-like structure

  

Source: Thirumalai, Devarajan - Institute for Physical Science and Technology, University of Maryland at College Park

 

Collection: Chemistry ; Biotechnology

 
45 Display As Presentations Sessions nmlkji nmlkj
 

Summary:  of gene- reporter molecule OFPNPG gfedc Dar-Bin Shieh -- 217. Anti-Her-2 Monoclonal Antibody Conjugated

  

Source: Bülthoff, Isabelle - Max-Planck-Institut für biologische Kybernetik

 

Collection: Biology and Medicine

 
46 Anti-HER-3 MAbs Inhibit HER-3-Mediated Signaling in Breast Cancer Cell Lines Resistant to Anti-HER-2 Antibodies
 

Summary:  and methods). Cell lysates were subjected to IP using anti-HER2 (a-HER2) or anti- HER3 (a-HER3) MAbs... the internalization process. The active mechanism of the therapeutic anti-HER2 anti- body HC is, in our cell system... determinant of the proliferation and invasiveness of breast cancer cells. The ...

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine

 
47 www.afm-journal.de FEATUREARTICLE
 

Summary:  nanocages were internalized by the cells. On the other hand, 70­80% of the anti-HER2-coated nanocages were... and 55 nm.[22] These nano- cages were functionalized with PEG, antibody (anti-HER2), and poly... on surface chemistry, the uptake of Au nanocages decreased in the order of PAA >> ...

  

Source: Wang, Lihong - Department of Biomedical Engineering, Washington University in St. Louis

 

Collection: Engineering ; Biology and Medicine

 
48 Nano Res (2010) 3: 222233222 Multiplexed Five-Color Molecular Imaging of Cancer Cells and
 

Summary:  (anti-Her2) to target Her2/neu protein (Fig. 1(a)) [19, 24]. #12;Nano Res (2010) 3: 222­233224 2.2 Five... and Color5-anti- Her2 at 4 °C for 1 h and then washed by phosphate buffered saline (PBS). Spec- troscopic... -anti-EGFR/Her1 and ...

  

Source: Dai, Hongjie - Department of Chemistry, Stanford University

 

Collection: Chemistry

 
49 Anticorps bispcifiques : quel avenir ? Andr Plegrin et Bruno Robert
 

Summary:  (CEA) et HER2, un AcBs anti-CEA/anti-HER2 a montré une meilleure captation tumorale que les fragments F... (ab')2 des anticorps parentaux [15]. Un AcBs recombinant reliant un scFv anti-HER2 à un scFv anti-HER3

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
50 Chemistry & Biology 13, 139147, February 2006 2006 Elsevier Ltd All rights reserved DOI 10.1016/j.chembiol.2005.10.015 Directed Evolution of ATP Binding Proteins
 

Summary:  -idiotypic protein domains selected from protein A-based affibody libraries. Proteins 48, 454­462. 8. Skerra, A

  

Source: Szostak, Jack W. - Department of Genetics, Harvard University

 

Collection: Environmental Sciences and Ecology ; Biology and Medicine

 
51 A Novel Form of the Plasminogen Activator Inhibitor Created by Cysteine Mutations Extends Its Half-Life: Relevance to
 

Summary:  and characterization of affibody-Fc chimeras produced in Escherichia coli. J. Immunol. Methods, 261: 199­ 211, 2002. 32

  

Source: Jankun, Jerzy - Departments of Physiology and Molecular Medicine & Urology, Medical College of Ohio

 

Collection: Biology and Medicine

 
52 AcceptedArticle Switching the fiber knob of oncolytic adenoviruses to avoid
 

Summary:  a knobless, affibody-targeted adenovirus type 5 vector. Gene Ther 2007; 14: 376-381. DOI: 10.1038/sj

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
53 {Editorial} What do we learn from HER2-positive breast cancer genomic profiles?
 

Summary:  Francisco, CA, USA) of anti-HER2 monoclonal antibodies. But do HER2-positive breast cancers form

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
54 Naomi J. Halas Department of Electrical and Computer Engineering
 

Summary:  M) A Biotin- anti-HER2 0 mM 0.123 mM 0.200 mM0.0125 mM 0.048 mM0.025 mM 0.165 mM T2 weighted images

  

Source: Mellor-Crummey, John - Department of Computer Science, Rice University

 

Collection: Computer Technologies and Information Sciences

 
55 See online version for legend, abbreviations, and references.1018 Cell 131, November 30, 2007 2007 Elsevier Inc. DOI 10.1016/j.cell.2007.11.013 SnapShot:EGFRSignalingPathway
 

Summary:  as a dual EGFR and HER2 inhibitor. Also approved for clinical applications are a humanized monoclonal anti-HER... 2 antibody and two anti- EGFR antibodies. (4) Downstream signaling: Receptor homo- or heterodimers

  

Source: Shilo, Benny - Department of Molecular Genetics, Weizmann Institute of Science

 

Collection: Biology and Medicine

 
56 Wien Med Wochenschr (2010) DOI 10.1007/s10354-010-0838-6
 

Summary:  . Modified anti-HER2 antibodies To increase the potency of antibody-directed ther- apy, the specificity... , Codony-Servat J, Albanell J, et al. Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal... . Expression of p95HER2, a truncated form of the HER2 receptor, and response to ...

  

Source: Chin-Sang, Ian - Department of Biology, Queen's University (Kingston)

 

Collection: Biology and Medicine

 
57 RESEARCH Open Access Antitumour effects of single or combined
 

Summary:  of therapy in breast and ovarian carcinomas with anti-HER2 mAbs as well as in non-Hodkin B cell lymphomas... in the clinic, such as anti-CD20, anti-HER2 or anti-EGF receptor, the exact mechanism of anti-tumour activity... the accessibility to the different EGFR ligands, but for ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
58 836 Current Drug Metabolism, 2009, 10, 836-841 1389-2002/09 $55.00+.00 2009 Bentham Science Publishers Ltd.
 

Summary:  sites. For instance, anti-HER2 immunoliposomes yielded 700-fold higher drug uptake compared to non... . After intravenous injection, the anti-HER2 liposomes were found mostly in the cytoplasm of cancer cells... .; Papahadjopoulos, D.; Benz, C. C. Tumor targeting using ...

  

Source: Zhang, Liangfang - Department of Nanoengineering, University of California at San Diego

 

Collection: Materials Science

 
59 Klinische Studien Gynkologische Onkologie
 

Summary:  )adjuvanter Anti-HER2-Therapie Xeloda (NIS): metastasiertes Mammakarzinom, First- oder Further-line ACT

  

Source: Manstein, Dietmar J. - Department of Biophysical Chemistry, Medizinische Hochschule Hannover

 

Collection: Biology and Medicine

 
60 Protein tyrosine kinase Syk modulates EGFR signalling in human mammary epithelial cells
 

Summary:  monoclonal a- Tubulin antibody (Sigma), mouse monoclonal anti-HER3 (UBI), mouse monoclonal anti-HER2 antibody... (13D1B1) and rabbit polyclonal anti-HER2-CT antibody [24]. Phos- phorylation state-specific antibodies... min with EGF (20 ng mlÀ 1 ) or Hergulin-h1 (Hrg-h1) (20 ng mlÀ 1 ). Anti-EGFR, ...

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine


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61 ISSN 1743-588910.2217/NNM.11.19 2011 Future Medicine Ltd Nanomedicine (2011) 6(4), 715728 715 Nanoparticle PEGylation for imaging and therapy
 

Summary:  monoclonal a- Tubulin antibody (Sigma), mouse monoclonal anti-HER3 (UBI), mouse monoclonal anti-HER2 antibody... (13D1B1) and rabbit polyclonal anti-HER2-CT antibody [24]. Phos- phorylation state-specific antibodies... min with EGF (20 ng mlÀ 1 ) or Hergulin-h1 (Hrg-h1) (20 ng mlÀ 1 ). Anti-EGFR, ...

  

Source: Zare, Richard N. - Department of Chemistry, Stanford University

 

Collection: Chemistry

 
62 A Tumor Vasculature Targeted Liposome Delivery System for Combretastatin A4: Design, Characterization, and In Vitro Evaluation
 

Summary:  by the cells also increased. Similar results were reported by Kirpotin et al31 with anti-HER2 immunoliposomes... 3261. 3. Park JW, Hong K, Kirpotin DB, Meyer O, Papahadjopoulos D, Benz CC. Anti-HER2 immunoliposomes... . 31. Kirpotin D, Park JW, Hong K, et al. Sterically stabilized ...

  

Source: 

 

Collection: Engineering ; Biology and Medicine

 
63 Quality and Renewal 2011 Kvalitet och Frnyelse 2011 (KoF11)
 

Summary:  by the cells also increased. Similar results were reported by Kirpotin et al31 with anti-HER2 immunoliposomes... 3261. 3. Park JW, Hong K, Kirpotin DB, Meyer O, Papahadjopoulos D, Benz CC. Anti-HER2 immunoliposomes... . 31. Kirpotin D, Park JW, Hong K, et al. Sterically stabilized ...

  

Source: Uppsala Universitet - Department of Population Biology

 

Collection: Environmental Sciences and Ecology

 
64 Lake, Douglas F. CURRICULUM VITAE
 

Summary:  DF. Reactivity of anti-Her-2/neu CTL to Her-2/neu modified peptides. Cancer Immunol. Immunother. 72

  

Source: Hall, Sharon J. - School of Life Sciences, Arizona State University

 

Collection: Environmental Sciences and Ecology

 
65 Klinische Studien Gynkologische Onkologie
 

Summary:  . Mammakarzinom, HER2 positiv, Rezidiv nach (neo)adjuvanter Anti-HER2-Therapie Xeloda (niS): Metastasiertes

  

Source: Manstein, Dietmar J. - Department of Biophysical Chemistry, Medizinische Hochschule Hannover

 

Collection: Biology and Medicine

 
66 PERSPECTIVES NATURE REVIEWS | CANCER VOLUME 4 | MAY 2004 | 361
 

Summary:  a human oncoprotein in a major cancer indication could be successful. Another anti-HER2 antibody, 2C4... gener- ation of anti-HER2 monoclonal antibodies that interfere with the mechanism of onco- genic signal... , Herceptin HER2 Approved for metastatic Humanized ...

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine

 
67 Int J Cancer. Author manuscript Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has
 

Summary:  for breast cancer treatment. Trastuzumab is a humanized anti-HER2 antibody that has been approved... protein/protein interactions as a target in the design of anti-HER2 agents. Ackowledgements: This work has

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
68 Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has anti-tumor effects in
 

Summary:  for breast cancer treatment. Trastuzumab is a humanized anti-HER2 antibody that has been approved... the inhibition of Grb2 protein/protein interactions as a target in the design of anti-HER2 agents. inserm

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
69 2007 by Taylor & Francis Group, LLC 5 Multifunctional Nanoparticles
 

Summary:  stabilized Anti-HER2 immunoliposomes: Design and targeting to human breast cancer cells in vitro... ­411, 2001. 81. Park, J. W. et al., Tumor targeting using anti-her2 immunoliposomes, Journal of Controlled

  

Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biotechnology ; Biology and Medicine

 
70 Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer
 

Summary:  delivery of liposome-encapsulated CK18 expression vectors by conjugation to anti-HER2/neu antibodies seems... , Shalaby R, Baselga J, Shao Y, Nielsen UB, Marks JD, Moore D, Papahadjopoulos D, Benz CC. Anti-HER2

  

Source: Gerstein, Mark - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine ; Biotechnology

 
71 Introduction Patients with breast carcinomas can display a different
 

Summary:  , Cal- ifornia, USA) at 1:100 dilution, and anti-Her-2 (AO485; DAKO Corp.) at 1:200 dilution. Scoring... , while a specific therapy with anti-Her-2 Ab's (Herceptin) is currently used in ER-negative breast cancer

  

Source: Roth, David B. - Langone Medical Center, New York University

 

Collection: Biology and Medicine

 
72 Studies of Global Biological and their Contribution to Complex Phenotype or From Integrative Genomics towards Functional
 

Summary:  - arrays are spotted with protein specific antibodies, aptamers or affibodies. Targeted protein abundances

  

Source: Goldschmidt, Christina - Department of Statistics, University of Warwick

 

Collection: Mathematics

 
73 www.landesbioscience.com Self/Nonself 1 Self/Nonself 1:4, 1-6; October/November/December 2010 2010 Landes Bioscience
 

Summary:  Pharmacol 2010; 79:330-8. 28. Gao J, Kou G, Wang H, Chen H, Li B, Lu Y, et al. PE38KDEL-loaded anti-HER2

  

Source: Fahmy, Tarek - Departments of Biomedical Engineering & Chemical and Environmental Engineering, Yale University

 

Collection: Materials Science ; Biology and Medicine

 
74 Vascular targeted single-walled carbon nanotubes for near-infrared light therapy of cancer This article has been downloaded from IOPscience. Please scroll down to see the full text article.
 

Summary:  al 2009 Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection

  

Source: Resasco, Daniel - School of Chemical Engineering and Materials Science, University of Oklahoma

 

Collection: Materials Science

 
75 Temporal Knowledge Representation for Scheduling Tasks in Clinical Trial Protocols
 

Summary:  -les-Pins, France, 2000. [9] M.A. Bookman, M.D. (study chair). GOG #160: A phase II evaluation of Anti-her2 antibody

  

Source: Washington at Seattle, University of - Structural Informatics Group (SIG)

 

Collection: Computer Technologies and Information Sciences ; Biology and Medicine

 
76 Elsevier Editorial System(tm) for BBA -Biomembranes Manuscript Draft
 

Summary:  visualization of two fluorophores using either a transfected cell line and an anti-HER2 antibody coupled... cells. Urano et al. made a pH-activatable probe coupled to the anti-HER-2 monoclonal antibody

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
77 10.1517/14712598.7.9.1 2007 Informa UK Ltd ISSN 1471-2598 1 1. Introduction
 

Summary:  Ab) [67], a full-length anti-HER-2 antibody was cloned into an adenovirus vector [68]. In a model

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
78 Atg5-Independent Sequestration of Ubiquitinated Mycobacteria
 

Summary:  polyubiquitin (left panel), K48-linked polyubiquitin (middle panel), or anti-her2 as an isotype control (IC

  

Source: Lippincott-Schwartz, Jennifer - Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development

 

Collection: Biology and Medicine

 
79 Integrative Genomics and Functional Explanation , Thorunn Rafner2
 

Summary:  . · Protein Arrays - arrays are spotted with protein specific antibodies, aptamers or affibodies. Targeted

  

Source: Goldschmidt, Christina - Department of Statistics, University of Warwick

 

Collection: Mathematics

 
80 From Global Studies of Biological Variation towards Functional Explanations of Phenotype
 

Summary:  . · Protein Arrays - arrays are spotted with protein specific antibodies, aptamers or affibodies. Targeted

  

Source: Goldschmidt, Christina - Department of Statistics, University of Warwick

 

Collection: Mathematics


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81 A N N U A L R E P O R T
 

Summary:  "Espressione intracellulare di uno spe- cifico Affibody per inibire la funzionalità di HER-1, mediante

  

Source: Milano-Bicocca, Università - Dipartimento di Informatica, Sistemistica e Comunicazione, Laboratory of Test and Analysis

 

Collection: Engineering ; Computer Technologies and Information Sciences

 
82 NON-INVASIVE MEASUREMENT OF DEEP TISSUE TEMPERATURE CHANGES
 

Summary:  . Cobleigh et al., \Multinational study of the e±cacy and safety of humanized anti-HER2 monoclonal antibody

  

Source: Yodh, Arjun G. - Departments of Radiology & Physics and Astronomy, University of Pennsylvania

 

Collection: Physics ; Biology and Medicine

 
83 Introduction Tumour cells generally grow in a hypoxic environment.
 

Summary:  for breast cancer (anti-HER2, anti- angiogenesis), it seems promising to study the regulation of a factor

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
84 BioMed Central Page 1 of 11
 

Summary:  , Keyomarsi K, Lee MH, Zhao J, Bast RG: Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone

  

Source: Hinow, Peter - Department of Mathematical Sciences, University of Wisconsin-Milwaukee

 

Collection: Mathematics

 
85 by Tarek M. Fahmy, Peter M. Fong, Amit Goyal, and W. Mark Saltzman,* Department of Biomedical Engineering,
 

Summary:  treatment with free drug90,103. Another group that showed similar indiscriminate results with anti-HER2

  

Source: Fahmy, Tarek - Departments of Biomedical Engineering & Chemical and Environmental Engineering, Yale University

 

Collection: Materials Science ; Biology and Medicine

 
86 Nanoparticles in Medicine: Therapeutic Applications and Developments
 

Summary:  44 Metallic nanoparticles Anti-HER2 antibody-targeted gold/silicon nanoparticles Nanoshell

  

Source: Zhang, Liangfang - Department of Nanoengineering, University of California at San Diego

 

Collection: Materials Science

 
87 In Vivo Photoacoustic Tomography of Chemicals: High-Resolution Functional and Molecular Optical Imaging at New Depths
 

Summary:  44 Metallic nanoparticles Anti-HER2 antibody-targeted gold/silicon nanoparticles Nanoshell

  

Source: Wang, Lihong - Department of Biomedical Engineering, Washington University in St. Louis

 

Collection: Engineering ; Biology and Medicine

 
88 Designed TPR Modules as Novel Anticancer Aitziber L. Cortajarena
 

Summary:  :2000 (anti-HER2,sc-284, Santa Cruz Biotechnology), 1:200 (antiphosphor-HER2, clone PN2A, Neomark- ers), and 1

  

Source: Mochrie, Simon - Department of Applied Physics, Yale University; Regan, Lynne - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine ; Biotechnology ; Materials Science ; Physics

 
89 Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: Novel heregulin/HER3-stimulated signaling pathway in glioma
 

Summary:  to immunoprecipitation (IP) using either polyclonal anti-PYK2 ( - PYK2), or polyclonal anti-HER2 ( -HER2) or monoclonal

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine

 
90 Therapeutic and diagnostic applications of dendrimers for cancer treatment Jesse B. Wolinsky, Mark W. Grinstaff
 

Summary:  the unconjugated dendrimer was not significantly taken up by cells. A similar study was performed using anti-HER2-G

  

Source: Boston University, Center for Nanoscience and Nanobiotechnology

 

Collection: Materials Science

 
91 N d'ordre 331 Au Laboratoire d'Etude de l'Intgration des Composants et Systmes Electroniques
 

Summary:  the unconjugated dendrimer was not significantly taken up by cells. A similar study was performed using anti-HER2-G

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
92 To subscribe, please call BIOWORLD Customer Service at (800) 688-2421; outside the U.S. and Canada, call (404) 262-5476.
 

Summary:  with anti-HER2 antibodies. ImmunoGen stands to gain up to $44 million in milestones in addition to royalties

  

Source: Utah, University of - Energy and Geoscience Institute, Geothermal Research Group

 

Collection: Renewable Energy ; Geosciences

 
93 ORIGINAL RESEARCH Open Access Syndecan-1 antigen, a promising new target for
 

Summary:  for the treatment of metastatic triple-negative breast cancer that cannot benefit from hormone therapy or anti-Her2

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
94 RESEARCH ARTICLE Open Access Genomic expression and single-nucleotide
 

Summary:  monoclonal anti-HER2 antibody (Neomarker RM 9103-S clone SP3, 1:200, membranous staining), a phospho-AKT (Ser

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
95 MAbs . Author manuscript Bispecific antibodies for cancer therapy: the light at the end of the tunnel?
 

Summary:  clinical trial of the bispecific antibody MDX-H210 (anti-FcgammaRI × anti-HER-2/neu) in combination

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
96 Bispecific antibodies for cancer therapy: the light at the end of the Patrick Chames1
 

Summary:  antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
97 323ISSN 2041-599010.4155/TDE.10.13 2010 Future Science Ltd Therapeutic Delivery (2010) 1(2), 323334 Special FocuS: oncology
 

Summary:  antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment

  

Source: Zhang, Liangfang - Department of Nanoengineering, University of California at San Diego

 

Collection: Materials Science

 
98 A Targeted Liposome Delivery System for Combretastatin A4: Formulation Optimization through Drug Loading and In
 

Summary:  .; Nielsen, U. B.; Marks, J. D.; Moore, D.; Papahadjopoulos, D.; Benz, C. C. Anti-HER2 immunoliposomes

  

Source: 

 

Collection: Engineering ; Biology and Medicine

 
99 A Novel Class of Small Molecule Inhibitors of and Lynne Regan,,
 

Summary:  in a humidified atmosphere of 5% CO2 at 37 °C. Western Blot antibody for rabbit polyclonal anti- HER2 (sc-284

  

Source: Mochrie, Simon - Department of Applied Physics, Yale University; Regan, Lynne - Department of Molecular Biophysics and Biochemistry, Yale University

 

Collection: Biology and Medicine ; Biotechnology ; Materials Science ; Physics

 
100 Distinct ADAM Metalloproteinases Regulate G Protein-coupled Receptor-induced Cell Proliferation and Survival*
 

Summary:  - tems. Mouse monoclonal ICR-3R antibody (28) and rabbit polyclonal anti-HER2/neu antibody have been

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine


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