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Sample search results for: a431 tumor xenografts

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1 Epidermal Growth Factor Receptor Inhibition Modulates the Microenvironment by Vascular Normalization to
 

Summary:  in A431 xenografts using 18 F-FAZA PET scanning with the nitroimidazole FAZA. Another group showed... /Principal Findings: Erlotinib treatment of human tumor cells in vitro and mice bearing xenografts in vivo led... response to chemotherapy and radiation, we performed ...

  

Source: Yodh, Arjun G. - Departments of Radiology & Physics and Astronomy, University of Pennsylvania

 

Collection: Physics ; Biology and Medicine

 
2 J Nucl Med . Author manuscript Noninternalizing monoclonal antibodies are suitable candidates for I125
 

Summary:  with tumor cell xenografts. For this purpose, nude mice bearing125 intraperitoneal A-431-derived tumors were... curves. A) Swiss nude mice bearing 1 2 mm xenograft A-431 tumor nodules were followed... ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
3 Non-internalizing monoclonal antibodies are suitable candidates for 125 radioimmunotherapy of small-volume peritoneal carcinomatosis
 

Summary:  of mice with tumor cell xenografts. For this purpose, nude mice bearing intraperitoneal A-431-derived... calibration curves. A) Swiss nude mice bearing 1--2 mm xenograft A-431 tumor nodules were followed... ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
4 [CANCER RESEARCH 61, 18051809, March 1, 2001] Advances in Brief
 

Summary:  ). The tumor size of U87 and U251 flank xenografts was determined for 50 days after cell inoculation... of metastases of human tumor cells from the xenografts to major organs, xenografts were established in mice... . Fifty days after the administration of Ad-HSV-tk/GCV therapy with trypsin ...

  

Source: Israel, Mark A.- Department of Genetics, Dartmouth College

 

Collection: Biology and Medicine

 
5 EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast
 

Summary:  obtained; these contained 66 nmol PEI (1.64 mg), 350 nmol Mel, and 70 nmol EGF. A431 Xenograft Treatment... transfection. (C) (poly IC)MPPE complexes eliminate A431 and MDA-MB-468 xenografts in mice. A431 and MDA-MB-468... ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
6 Fig 1. A: Illustration of Tc-IL-1ra-Fc competitive targeting IL-1 receptors; B & C: SPECT images
 

Summary:  ) in the mouse HCT116 colon cancer xenograft . Inflammation and angiogenesis are linked in the progression... of malignancies. Inflammation can promote all stages of tumor development through multiple mechanisms, which... molecules in the tumor microenvironment provide mechanisms for tumor cell expansion. ...

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine

 
7 Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo
 

Summary:  (xenograft) analysis of tumor progres- sion and treatment. However, the extent to which cultured prep... or in xenograft tumors. Likewise, distinct groups of stromal (mouse) enzyme activities were found that either... infiltrated or were ex- cluded from xenograft ...

  

Source: Cravatt, Benjamin - Department of Cell Biology, Scripps Research Institute

 

Collection: Biology and Medicine

 
8 A Quantitative Model for the Dynamics of Serum Prostate-Specific Antigen as a Marker for Cancerous
 

Summary:  of PSA as low as 0.05 g/ml.11 Anatomy of Xenografts Being located subcutaneously as spherical tumor... increases exponentially in both patients and in tumor xenografts. Because we will compare the model results... to experimental data received from xenografts in mice, we assume that an ...

  

Source: Swanson, Kristin R.- Departments of Pathology & Applied Mathematics, University of Washington at Seattle

 

Collection: Biology and Medicine

 
9 ScientificWorldJournal . Author manuscript Therapeutic antibodies for the treatment of pancreatic cancer
 

Summary:  line A431) as large as 1.2 cm ( ). A phase II clinical trial comparing gemcitabine plus erlotinib... and obtained a marked tumor growth inhibition in xenografted mice. As expected, the treatment induced... at the tumor site using xenografted athymic nude mice. More ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
10 Identification of alterations in DNA copy number in host stromal cells during tumor progression
 

Summary:  copy num- ber analysis to murine stromal DNA isolated from human xenograft tumors that were formed... Cells in Human Xenograft Tumors. We reasoned that if genetically aberrant cancer cells coevolve... a complex xenograft tumor that contains stromal participants in a ...

  

Source: Botstein, David - Lewis-Sigler Institute for Integrative Genomics & Department of Molecular Biology, Princeton University

 

Collection: Biology and Medicine

 
11 SUPPLEMENTARY FIGURES Supplementary Figure 1. T2-weighted MRI cross-sections of low-Fe AMB-1 (grown with
 

Summary:  version of Figure 6, with arrows pointing to tumors. AMB- 1 produce positive contrast in tumor xenografts... ;2 Supplementary Figure 2. Correlation between AMB-1 cell number and T1-weighted positive contrast in mouse tumors... . A-C, T1-weighted axial-slice images of a tumor pre-injection ...

  

Source: Matin, A.C. - Department of Microbiology and Immunology, Stanford University

 

Collection: Biology and Medicine ; Environmental Management and Restoration Technologies

 
12 Brief intraperitoneal radioimmunotherapy of small peritoneal carcinomatosis using high activities of non-internalizing 125
 

Summary:  analysis. Athymic nude mice bearing intraperitoneal A-431 tumor cell xenografts were treated by A) Bip-125... Mice were i.p. grafted with 0.7 × 106 A-431 cells suspended in 0.3 ml DMEM medium. Tumor growth... and control mice. Figure 3. Survival ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
13 J Nucl Med . Author manuscript Brief intraperitoneal radioimmunotherapy of small peritoneal
 

Summary:  bearing intraperitoneal A-431 tumor cell xenografts were treated by A) Bip- I-35A7-RIT. The125 percentage... were i.p. grafted with 0.7 10 A-431 cells suspended in 0.3 ml DMEM medium. Tumor growth was assessed 3... manuscript Page /9 11 Figure 3 ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
14 Proc. Natl. Acad. Sci. USA Vol. 94, pp. 81048109, July 1997
 

Summary:  within solid tumors and to define the consequences, we have studied tumor xenografts of a set of hepatoma... of the tumor. To address these questions we grew the Hepa-1 cells and selected derivatives as xenografts... , vascularity, and growth be- tween the tumor ...

  

Source: Bradfield, Christopher A. - McArdle Laboratory for Cancer , University of Wisconsin at Madison

 

Collection: Biology and Medicine

 
15 [CANCER RESEARCH 61, 63776381, September 1, 2001] Advances in Brief
 

Summary:  by injecting 5 106 A431 cell into both flanks of athymic mice (n five/group). When tumors were 5 mm ("day 0... into established A431 tumors (Fig. 4, B­C). The change-point test (20) revealed that the tumor growth pattern... of CRAdsCAR-EGF or ...

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
16 Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases
 

Summary:  , dissociating the inhibitory peptide and allowing the CPP to bind to and enter tumor cells. In mice, xenografts... normal and tumor tissue, we injected nude mice xenografted with the green fluorescent protein (GFP... the completeness of tumor surgery. Fig. 5 ...

  

Source: Tsien, Roger Y. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Chemistry

 
17 In vivo therapeutic synergism of anti-EGFR and anti-HER2 monoclonal antibodies against pancreatic carcinomas
 

Summary:  : The combined mAb treatment significantly inhibited tumor progression of the BxPC-3 xenografts, as compared... the different forms of mAb therapy on tumor xenografts of various sizes, two series of representative... of a synergic effect rather than an additive one. Results from larger ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
18 Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has anti-tumor effects in
 

Summary:  time an in vivo activity of a Grb2 SH3 inhibitor, in human HER2 tumor xenograft in mice. These results... and BK111 xenografts and BK130JAM xenograft were established by subcutaneous implantation of tumor... animals were killed when tumor volume reached 2000 mm3 . As ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
19 Int J Cancer. Author manuscript Grb2-SH3 ligand inhibits the growth of HER2+ cancer cells and has
 

Summary:  ) xenograft in nude mice and potentiated the anti-tumor effect of docetaxel in a+ HER2 hormone... & dosage ; pharmacology ; Time Factors ; Tumor Burden ; drug effects ; Xenograft Model Antitumor Assays... , xenografted animals were killed when tumor volume reached ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
20 Evaluation of radiolabeled ML04, a putative irreversible inhibitor of epidermal growth factor receptor, as a bioprobe for PET imaging of
 

Summary:  on the phosphorylation of EGFR were evaluated in A431 vulval carcinoma, MDA-MB-468 breast carcinoma, PC10 lung carcinoma... and NCI-H1975 NSCLC cells, as previously described [41]. Briefly, A431 (1Â105 cells/well), MDA-MB-468 (3Â... cells: 2.8. Specific binding studies of [18 F]ML04 in intact ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine


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21 A Novel Substrate Mimetic Inhibitor of PKB/Akt Inhibits Prostate Cancer Tumor Growth in Mice by Blocking the PKB Pathway
 

Summary:  .03 Windows (GraphPad Software, San Diego, CA). Cells and Cell Culture. PC3, LNCaP, A431, and MCF10F cell... of activated PKB/Akt, in comparison to a cancer cell line where PKB is not activated, A431, as well... activation of PKB such as A431 cells and the normal cell ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
22 School of Life Sciences School of Engineering IBI Institute of Bioengineering / Institut de bioingnierie
 

Summary:  knockdown antagonized formation of lymph node metastasis in xenografted tumors. Furthermore, expression... and their matching axillary lymph nodes, we show here that intrametastatic lymphatic vessels and bulk tumor cell... model of tumor bulk invasion, human mammary carcinoma cells caused circular defects in ...

  

Source: Floreano, Dario - Laboratory of Intelligent Systems, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Computer Technologies and Information Sciences ; Engineering

 
23 Mabs against Pancreatic cancer Therapeutic antibodies for the treatment of pancreatic cancer
 

Summary:  vulvar epidermoid carcinoma cell line A431) as large as 1.2 cm3 (35). A phase II clinical trial comparing... , the fragment inhibits tumor growth in a murine xenograft model, through inhibition of angiogenesis... at the tumor site using xenografted athymic nude mice. ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
24 School of Life Sciences School of Engineering IBI Institute of Bioengineering / Institut de bioingnierie
 

Summary:  tumor xenografts using the chorioallantoic membrane model revealed tumor eradication and destruction... of tumor vasculature. Hence, intralysosomal sequestration of photosensitizer hydrophobic weak base drugs... can be efficiently harnessed to eradicate malignant tumors via lysosomal ...

  

Source: Floreano, Dario - Laboratory of Intelligent Systems, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Computer Technologies and Information Sciences ; Engineering

 
25 Cancer Sci | October 2009 | vol. 100 | no. 10 | 18701879 doi: 10.1111/j.1349-7006.2009.01269.x 2009 Japanese Cancer Association
 

Summary:  protein (HspBP) 1 from human brain tumors, their xenografts grown in immune-compromised mice... . This holds true for the xenograft and syngeneic murine tumor models. In biochemical affinity chromatography... directly to brain tumor cell surfaces, both in cell lines and disaggregated ...

  

Source: Limesand, Sean - Department of Animal Sciences, University of Arizona

 

Collection: Biology and Medicine

 
26 Journal of Neuro-Oncology 64: 101116, 2003. 2003 Kluwer Academic Publishers. Printed in the Netherlands.
 

Summary:  -specific doxorubicin immunoconjugate in a human brain tumor xenograft model. Neurosurgery 46(3): 704­709, 2000 39... in the Netherlands. Immunotoxin therapy for CNS tumor Edward Rustamzadeh1 , Walter C. Low1,2 , Daniel A. Vallera3... of practice in treating malignant brain tumors. Unfortunately, the ...

  

Source: Low, Walter C. - Department of Integrative Biology and Physiology, University of Minnesota

 

Collection: Biology and Medicine

 
27 Ovarian cancer is the most lethal cause of death among the gynecological cancers. Conventional therapies of surgery and chemotherapy failed to significantly improve the survival rates for this disease. Therefore
 

Summary:  delivery of genes to tumor tissues such as transductional targeting and transcriptional targeting are also... overexpression is correlated with increased tumor growth, ascites fluid accumulation, metastases, poor prognosis... angiogenesis by antagonizing VEGF is employed for ovarian cancer gene therapy to inhibit tumor ...

  

Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution,

 

Collection: Biology and Medicine ; Environmental Sciences and Ecology

 
28 Cooperative nanomaterial system to sensitize, target, and treat tumors
 

Summary:  -associated cells upon thermal treatment. Mice containing xenografted MDA-MB- 435 tumors that are treated... with a maximum optical absorption of 800 nm are found to accumulate passively in a MDA-MB-435 xenograft tumor... ;ligand based on a screen of several tumor targeting peptides in ...

  

Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biotechnology ; Biology and Medicine

 
29 Original article Combined Cetuximab and Trastuzumab are superior to Gemcitabine in the
 

Summary:  tumor xenografts, by IHC, the EGFR expression, the EGFR phosphorylation level, and the proliferative Ki... ;9:39- 44. 20. Perera RM, Narita Y, Furnari FB, et al: Treatment of human tumor xenografts with monoclonal... xenografts Tumor were resected 7 days after the ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
30 [CANCER RESEARCH 62, 37293735, July 1, 2002] Platelet-derived Growth Factor (PDGF) Autocrine Signaling Regulates Survival and
 

Summary:  phenotype. Oral administration of CT52923 to nude mice in a xenograft tumor model produces a significant... T3 fibroblasts, human glioblastoma- derived A172, T98G, U251, human carcinoma-derived A431, MDA468... the experiment, 0.5 ml of fresh complete medium (without CT52923) was added every 5 days. ...

  

Source: Israel, Mark A.- Department of Genetics, Dartmouth College

 

Collection: Biology and Medicine

 
31 [Cell Cycle 4:2, e82-e84, EPUB Ahead of Print: http://www.landesbioscience.com/journals/cc/abstract.php?id=1492; February 2005]; 2005 Landes Bioscience e82 Cell Cycle 2005; Vol. 4 Issue 2
 

Summary:  xenograft tumors formed by the invasive breast cancer line MDA-MB-231 were found to exhibit profound... -3 Many human cancer lines also form tumors in immune deficient mice, thereby providing xenograft models... established orthotopic xenograft tumors of the invasive ...

  

Source: Cravatt, Benjamin - Department of Cell Biology, Scripps Research Institute

 

Collection: Biology and Medicine

 
32 89Zr-Labeled N-succinyldesferrioxamine-ranibizumab [ [89Zr]-Ranibizumab]
 

Summary:  in xenograft tumors on athymic nude mice and to predict tumor response to VEGF-dependent anti- angiogenic... ), or Colo205 (a human colorectal adenocarcinoma cell line) xenograft tumors (7). Other Sources... in nude mice bearing SKOV-3 cell xenograft ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
33 Priority Report Metformin Decreases the Dose of Chemotherapy for
 

Summary:  xenografts, the drugs were administered by i.p. injection near the tumors (3). However, clinical use... and relapse in breast xenografts. A, tumor volume (mean Æ SD) in mice injected (on day 0) with transformed ER... xenograft tumors with paclitaxel (Fig. 2A) or ...

  

Source: 

 

Collection: Biology and Medicine

 
34 [CANCER RESEARCH 63, 72327240, November 1, 2003] An Integrated Approach to Measuring Tumor Oxygen Status Using Human
 

Summary:  xenograft and its vector-only transfected control tumor as a model. Specifically, the work reports MVD... and is validated by direct measurements. We used a reproducible s.c. human tumor xenograft model for the purpose... [CANCER RESEARCH 63, 7232­7240, November 1, 2003] An Integrated Approach to Measuring ...

  

Source: Yodh, Arjun G. - Departments of Radiology & Physics and Astronomy, University of Pennsylvania

 

Collection: Physics ; Biology and Medicine

 
35 In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancerw
 

Summary:  . We now show that ACPPs can target many xenograft tumor models from different cancer sites, as well... and MMP-9 activity reduce selective ACPP uptake by tumor xenografts Immunodeficient mice harboring HT-1080... of the xenografts with large, fast growing tumors ...

  

Source: Tsien, Roger Y. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Chemistry

 
36 Imaging recognition of multidrug resistance in human breast tumors Tc-labeled monocationic agents and a high-resolution
 

Summary:  in vivo in small animals with size-limited tumor xenografts, a high- resolution SPECT camera is more... curves of 99m Tc-labeled monocat- ionic agents in MCF7/S and MCF7/D40 human breast- tumor xenografts... in the tumor-xenografted rats [10]. The greater wash- out of 99m Tc-furifosmin ...

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine

 
37 Potential 18 F-labeled biomarkers for epidermal growth factor receptor
 

Summary:  then radiolabeled with 18 F and cell binding experiments, biodistribution and PET studies in A431 tumor-bearing mice... with A431 cells (3 106 in 200 L sterile PBS). Tumor growth was checked every 2­3 days by calipers. One... in vitro for inhibition of EGFr ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
38 Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and
 

Summary:  or epithelial cells is associated with a loss of stem cell markers and tumorigenicity. In vivo xenograft tumor... -beige (C.B-Igh-1b/GbmsTac- Prkdcscid-Lystbg N7) mice. Nine primary cultures formed xenograft tumors after... patient biopsies were named ovc316-PC, ovc805-PC, etc; sections or ...

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
39 PRECLINICAL STUDY Adult human mesenchymal stem cells enhance breast
 

Summary:  -independent tumor growth of breast carcinoma Using the same xenograft model, we injected immuno- compromised SCID... and integrate into the tumor stroma. We demonstrate here the effect of hMSCs on primary breast tumor growth... and the progression of these tumors to hormone independence. ...

  

Source: McLachlan, John - Environmental Endocrinology Laboratory, Tulane University

 

Collection: Environmental Sciences and Ecology

 
40 Small-animal models and imaging studies in CGRI
 

Summary:  and Zhonglin Liu #12;Delayed images of 99mTc-glucarate in A549 lung cancer xenograft. Tumor 10 min 24 hrs4 hrs... ) in xenografted tumor model in SCID mice using dynamic SPECT 99mTc-sestamibi imaging Without MDR With MDR A series... +) Tumor (NIS-) 99mTcO4 - 3D Images in a mouse with ...

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine


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41 Preclinical Evaluation of 2-[4-(7-Chloro-2-quinoxalinyloxy)phenoxy]-propionic Acid as a Modulator of Etoposide in Human
 

Summary:  animals in each group. B, tumor growth delay curves of WSU-WM-bearing SCID xenografts treated with XK469... ), we proceeded to address the in vivo effect of XK469, as a sensitizer of WSU-WM xenograft tumors... was to create an indolent tumor scenario in SCID mice. As described earlier, ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
42 LABELED EGFR-TK IRREVERSIBLE INHIBITOR (ML03): IN VITRO AND IN VIVO PROPERTIES, POTENTIAL AS PET BIOMARKER FOR CANCER AND
 

Summary:  was obtained in cells. An A431 tumor-bearing rat model was developed and the validity of the model was tested... of the samples without A431 cells. In vivo studies with [11 C]ML03: biodistribution in tumor-bearing rats All... , or in the neck with ...

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
43 A quantitative theory of solid tumor growth, metabolic rate and vascularization
 

Summary:  , is that human to mouse tumor xenografts will grow at a rate similar to endogenous mouse tumors, as opposed... of human tumor xenografts. Cancer Res 49: 3759-3764. 20. Gullino PM, Grantham FH (1961) Studies... 1 A quantitative theory of solid tumor growth, metabolic ...

  

Source: Santa Fe Institute

 

Collection: Multidisciplinary Databases and Resources

 
44 10.1517/14728222.11.10.1287 2007 Informa UK Ltd ISSN 1472-8222 1287 1. Introduction
 

Summary:  of the amplified gene in A431 epidermoid carcinoma cells. Nature (1984) 309(5967):418-425. ·· The identification... of TACE-dependent EGFR ligand shedding attenuated tumor growth in xenograft models. 81. LIU X, FRIDMAN JS... activity in several tumor types. This review presents the ...

  

Source: Kenny, Paraic - Department of Developmental and Molecular Biology , Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
45 RESEARCH ARTICLE Open Access Pentastatin-1, a collagen IV derived 20-mer
 

Summary:  decreased the invasion of microvessels in angioreactors and the rate of tumor growth in the xenograft model... tumor xenograft model Animal protocols were approved by the Animal Care and Use Committee at the Johns... .05 beginning at concentrations of 30 g/mL. In the tumor ...

  

Source: Popel, Aleksander S. - Department of Biomedical Engineering, Johns Hopkins University

 

Collection: Engineering ; Biology and Medicine

 
46 The FASEB Journal express article 10.1096/fj.01-0421fje. Published online November 29, 2001. In vivo targeting of SF/HGF and c-met expression via
 

Summary:  subcutaneous glioma xenografts via liposome-DNA complexes significantly inhibited tumor growth as well as tumor... .c. xenografts with intravenous injections of liposome-DNA complexes every 10 days and monitored tumor size... grew 24- and 23- fold, respectively. In contrast, ...

  

Source: Blackshaw, Seth - Department of Neuroscience, Johns Hopkins University

 

Collection: Biology and Medicine

 
47 3-D Reconstruction of Tumor Vascular Networks Most solid tumors consist of optically dense tissue. Therefore
 

Summary:  3-D Reconstruction of Tumor Vascular Networks Most solid tumors consist of optically dense tissue... is difficult. We propose a method to reconstruct tumor vascular networks using confocal intravital microscopy... of tumor vascular networks in optically dense tissue with disorganized topology is possible ...

  

Source: Andrzejak, Artur - Konrad-Zuse-Zentrum für Informationstechnik Berlin; Prohaska, Steffen - Konrad-Zuse-Zentrum für Informationstechnik

 

Collection: Computer Technologies and Information Sciences

 
48 Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence
 

Summary:  and -9 in xenograft and transgenic tumor models (13­15). ACPPs are short polycations attached via... -receptor positive and negative ovarian tumor xenografts. Invest Radiol 37:199­204. 6. Towner RA, et al. (2008... would be of great value for clinical detection and staging of tumors. We ...

  

Source: Tsien, Roger Y. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Chemistry

 
49 2011;71:5923-5931. Published OnlineFirst August 16, 2011.Cancer Res Kasper Toustrup, Brita Singers Srensen, Marianne Nordsmark, et al.
 

Summary:  of xenograft tumors from human squamous cell carcinoma cell lines, we verified the in vivo relevance... -positive, obtained from the American Type Culture Collection). Xenograft tumors for in vivo validation were generated... tissue In autoradiographic studies of xenograft ...

  

Source: Wiuf, Carsten - Bioinformatics Research Center, University of Aarhus

 

Collection: Biotechnology

 
50 Imaging recognition of inhibition of multidrug resistance in human breast cancer xenografts using 99m
 

Summary:  determina- tion of radiotracer kinetics in mice with xenografted tumors has been reported in a previous... -resistant properties of the MCF7/ AdrR cells remain in the xenografted tumors, Western blot analysis was applied... in the xenografted MCF7/AdrR tumors. There ...

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine

 
51 Radiol Onco11997; 31: 291-7. Interstitial fluid pressure as an obstacle in treatment of solid
 

Summary:  and oxygenation in a human tumor xenograft. Cancer Res 1996; 56: 964-8. 17. Boucher y, Lee I, Jain RK. Lack... tumors Jani Pusenjak and Damijan Miklavcic University of Ljubljana, Faculty of Electrical Engineering... these drugs failed in solid tumor treatment in in vivo conditions because of inadequate ...

  

Source: Ljubljana, University of - Faculty of Electrical Engineering, Laboratory of Biocybernetics

 

Collection: Engineering ; Biology and Medicine

 
52 Evaluation of Radiolabeled Type IV Collagen Fragments as Potential Tumor Imaging Agents
 

Summary:  localize within tumor xenografts in a receptor specific manner in vivo. EXPERIMENTAL SECTION Reagents. All... , 1 mg/mL BSA, and stored in aliquots at -80 °C. Membranes from xenografted tumor were prepared... from Xenografted SKOV3 tumor. The specific binding of ...

  

Source: Anderson, Carolyn J. - Department of Molecular Biology and Pharmacology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
53 Theranostics 2011, 1 http://www.thno.org
 

Summary:  in subcutaneous human tumor xenograft models in mice. TR-MRI analyses of the v3-targeted and non-targeted SPPMs... xenograft models, consistent with the targeting of mouse angiogenic endothelium despite tumor inoculation... superparamagnetic nanoprobes in dif- ferent tumor ...

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine

 
54 SPECT Imaging of Cell Death Using 99m Tc-labeled C2A Domain of Synaptotagmin I
 

Summary:  of 99m Tc-C2A tumor targeting, xenografted breast tumors were grown by implanting 5 × 106 human MCF7... infarction and anti-tumor chemotherapy. Fluorescently and radiolabeled C2A as targeted molecular probes have... . Second, we are investigating the in vivo targeting properties of 99m Tc-C2A in evaluating ...

  

Source: Arizona, University of - Center for Gamma-Ray Imaging

 

Collection: Engineering ; Biology and Medicine

 
55 Modeling of interstitial uid pressure in solid Jani Pusenjak, Damijan Miklavcic *
 

Summary:  pressure in a human tumor xenograft: Network analysis and mechanistic interpretation, Microvascular... Modeling of interstitial ¯uid pressure in solid tumor Jani Pusenjak, Damijan Miklavcic * Faculty... obstacles for macromolecular agents up- take and distribution in solid tumors. It has been demonstrated

  

Source: Ljubljana, University of - Faculty of Electrical Engineering, Laboratory of Biocybernetics

 

Collection: Engineering ; Biology and Medicine

 
56 Optimal Design for First In Human Studies to Investigate the Pharmacokinetic/Pharmacodynamic Behaviour
 

Summary:  kinase inhibitor. Data from tumor growth kinetics Xenograft model in mice and from in vivo target... ) and tumor growth data, which were our pharmacodynamic measures. An indirect response model was used to de... - scribe plasma concentrations and observed pSMAD data. The model integrated factors within the ...

  

Source: Bogacka, Barbara - School of Mathematical Sciences, Queen Mary, University of London

 

Collection: Mathematics

 
57 Peptides Derived from Type IV Collagen, CXC Chemokines,
 

Summary:  -Containing Proteins Inhibit Neovascularization and Suppress Tumor Growth in MDA-MB-231 Breast Cancer Xenografts1... xenografts. In vivo tumor xenograft models. Animal protocols were approved by the Institutional Care and Use... performed on tumor ...

  

Source: Popel, Aleksander S. - Department of Biomedical Engineering, Johns Hopkins University

 

Collection: Engineering ; Biology and Medicine

 
58 2-[18F]Fluoropropionyl-osteosarcomaspecific peptide-1 (ASGALSPSRLDT)
 

Summary:  Med] Osteosarcoma typically affects adolescents and represents the most common primary bone tumor in childhood (1... , angiogenesis, blood coagulation, and tumor metastasis. HSPGs are overexpressed on a variety of tumor cells... ]fluoropropionyl-OSP-1 ([18F]FP- OSP-1), which was then evaluated for positron emission tomography (PET) ...

  

Source: Levin, Judith G. - Laboratory of Molecular Genetics, National Institutes of Health

 

Collection: Biology and Medicine

 
59 The FASEB Journal Research Communication Rapid xenograft tumor progression in beta-arrestin1
 

Summary:  The FASEB Journal · Research Communication Rapid xenograft tumor progression in beta-arrestin1... inoculating tumor cells in them. We found that the xenograft tumor initiated earlier and grew more rapidly... ., Gang Pei. Rapid xenograft tumor ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
60 Biomimetic amplification of nanoparticle homing to tumors Derfus, Meng Yang, Robert M. Hoffman, Sangeeta Bhatia, Michael J. Sailor, and Erkki Ruoslahti
 

Summary:  kg) into BALB/c nude mice bearing MDA-MB-435 human breast cancer xenograft tumors measuring 1­1.5 cm... -SPIO nanoparticles in tumor vessels. Mice bearing MDA-MB-435 xenografts were injected with Ni-liposomes and CREKA... clotting on nanoparticle accumulation in tumors. Mice bearing ...

  

Source: Bhatia, Sangeeta - Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (MIT)

 

Collection: Biotechnology ; Biology and Medicine


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61 Three-Dimensional Diffuse-Interface Simulation of Multispecies Tumor GrowthII
 

Summary:  Three-Dimensional Diffuse-Interface Simulation of Multispecies Tumor Growth­II: Investigation... of Tumor Invasion H.B. Frieboes a , S.M. Wise b , J.S. Lowengrub b , V. Cristini a,b,1 a... in Part I, we investigate non-symmetric tumor growth and invasion in two and three dimensions using

  

Source: Cristini, Vittorio - Departments of Biomedical Engineering & Mathematics, University of California, Irvine

 

Collection: Mathematics ; Engineering

 
62 Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells
 

Summary:  ), and it generates tumors at high frequency in mouse xenografts (Fig. 1B). In contrast, the remaining 90... to form mammospheres and are 100-fold less efficient at causing tumors in mouse xenografts. As observed... by sorted CSCs (CD44high /CD24low ) and NSCCs (CD44low /CD24high ). (B) ...

  

Source: 

 

Collection: Biology and Medicine

 
63 Radiocurability by targeting tumor necrosis factor-alpha using a bispecific antibody in carcinoembryonic antigen transgenic mice
 

Summary:  in tumor xenograft models ( , ). These results supported the view that the interactions between TNF and RT... Tumor Necrosis Factor-alpha augments radiation effects against human colon tumor xenografts. Anticancer... Radiocurability by targeting tumor necrosis ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics

 
64 The Wayne State University Waldenstrom's Macroglobulinemia Preclinical Model for Waldenstrom's Macroglobulinemia
 

Summary:  or morphologic transformation. WSU-WM-SCID Mouse Xenograft Model This is a subcutaneous tumor model developed... tumor cell lines growing in vitro. However, tissue sections of WSU-WM xenografts growing in SCID mice... University Waldenstrom's Macro- globulinemia xenograft model in mice ...

  

Source: Brand, Paul H. - Department of Physiology and Pharmacology, University of Toledo

 

Collection: Biology and Medicine

 
65 Supporting Information Olson et al. 10.1073/pnas.0910283107
 

Summary:  rates R1 = 1/T1 in HT1080 tumor xenografts, before and 24 or 48 h after injection of 250 nmol... Supporting Information Olson et al. 10.1073/pnas.0910283107 Importance of MMPs in Tumor Biology... and Pathology MMP-2 and -9 are proteases whose activity is intimately involved in the process of tumor invasion

  

Source: Tsien, Roger Y. - Department of Chemistry and Biochemistry, University of California at San Diego

 

Collection: Chemistry

 
66 ORIGINAL RESEARCH Open Access Syndecan-1 antigen, a promising new target for
 

Summary:  cancer immuno-PET and radioimmunotherapy. A preclinical study on MDA-MB-468 xenograft tumors Caroline... . Immunohistochemistry Syndecan-1 expression was further investigated by immu- nohistochemistry on xenograft tumors... cells, intense membrane immunostaining of carcinoma cells from ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
67 ORIGINAL ARTICLE Paraic A. Kenny
 

Summary:  siRNAs significantly attenuated the growth of these tumor cells in xenografts. The role of TACE... as single agents and in combination with estab- lished chemotherapies in pre-clinical tumor xenograft models... expression of the amplified gene in A431 epidermoid ...

  

Source: Kenny, Paraic - Department of Developmental and Molecular Biology , Albert Einstein College of Medicine, Yeshiva University

 

Collection: Biology and Medicine

 
68 EARLY ONLINE RELEASE This is a provisional PDF of the author-produced electronic
 

Summary:  prevalent among real tumors and xenografts than among cell lines, LOH at the p53 locus is more prevalent... among xenografts than among real tumors or cell lines, and LOH at the Rb locus is equally prevalent... , and xenografts. 100K data was obtained from prostate ...

  

Source: Wong, Wing Hung - Department of Statistics, Stanford University

 

Collection: Mathematics ; Biology and Medicine

 
69 School of Life Sciences School of Engineering IBI Institute of Bioengineering / Institut de bioingnierie
 

Summary:  for the growth of tumor cells but not of normal tissue has been pursued for many years. However this therapeutic... have engineered and validated in xenograft models: (i) human arginase for L-Arg depletion therapy... for the treatment of hepatocellular carcinomas, metastatic melanomas and other L-Arg auxotrophic tumors; this ...

  

Source: Guerraoui, Rachid - Faculté Informatique et Communications, Ecole Polytechnique Fédérale de Lausanne

 

Collection: Computer Technologies and Information Sciences

 
70 Three-dimensional imaging of xenograft tumors using optical computed and emission tomography
 

Summary:  Three-dimensional imaging of xenograft tumors using optical computed and emission tomography Mark... 116 xenograft tumors, about 1 cc in dimension, which were transfected with constitutive red... for relating tissue structure and function as demonstrated here in relation to xenograft ...

  

Source: Rockey, Don - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
71 Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003,
 

Summary:  Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice... and the tumor suppressor p53. Thus, a group of specific chemical compounds called `signal therapeutics... -soluble derivative of AG 879, on human pancreatic cancer (Capan-1) xenograft in mice. Among these PAK1-blocking

  

Source: Levitzki, Alexander - Department of Biological Chemistry, Hebrew University of Jerusalem

 

Collection: Biology and Medicine

 
72 ORIGINAL ARTICLE Suppression of colorectal tumor growth by regulated
 

Summary:  . The potential of this system in cancer therapy was evaluated in experimental animals. Tumor xenograft models... tumor cell growth in vitro and inhibited tumor xenograft growth in vivo. Materials and methods Cells... experi- ments were performed according to the Animal Research Committee ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
73 Provisional Program January 27, 2012 08:30 -08:50 Coffee
 

Summary:  of biomarkers using xenograft models: Identification of exosomes as biomarker treasure chest 10:00 - 10... :45 Simon Hayward, Vanderbilt-Ingram Cancer Center, Tennessee, US Stromal evolution and prostate tumor

  

Source: Løw, Erik - Matematisk institutt, Universitetet i Oslo

 

Collection: Mathematics

 
74 Antitumor efficacy of a novel polymerpeptidedrug conjugate in human tumor xenograft models
 

Summary:  Antitumor efficacy of a novel polymer­peptide­drug conjugate in human tumor xenograft models Ying... -9. 1521ANTITUMOR EFFICACY OF A NOVEL POLYMER­PEPTIDE­DRUG CONJUGATE IN HUMAN TUMOR XENOGRAFT MODELS... OF A NOVEL POLYMER­PEPTIDE­DRUG CONJUGATE IN HUMAN TUMOR ...

  

Source: Chau, Ying - Department of Chemical Engineering, Hong Kong University of Science and Technology

 

Collection: Biology and Medicine

 
75 Intratumoral Delivery of B-Lapachone via Polymer Implants for Prostate Cancer Therapy
 

Summary:  -Lapachone release kinetics from millirods was determined in vitro and in vivo. PC-3 prostate tumor xenografts... (D,L-lactide-co-glycolide) millirods were directly implanted inside PC-3 tumor xenografts followed by examination of drug release... significant antitumor efficacy of h-lapachone in PC-3 ...

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine

 
76 Optical Tomographic Imaging of Tumor Response to Anti-Angiogenic Drugs in Small Animals
 

Summary:  ] J. Huang, et al, "TNP 470 promotes initial vascular sprouting in xenograft tumors," Molecular Cancer... of the vascular endothelial growth factor signaling inhibitor AZD2171 in Calu 6 human lung tumor xenografts... Optical Tomographic Imaging of Tumor Response to Anti-Angiogenic Drugs in ...

  

Source: Hielscher, Andreas - Department of Biomedical Engineering, Columbia University

 

Collection: Engineering ; Biology and Medicine

 
77 ORIGINAL ARTICLE A heparan sulfate-targeted conditionally replicative
 

Summary:  -LM3 cells and xenograft tumors, we performed flow cyto- metric analysis. CAR expression... Immunohistochemical staining of M4A4-LM3 xenograft tumors showed that HSPG staining was pronounced in blood vessel... was significantly upregulated in the M4A4-LM3 xenograft ...

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
78 Leading Edge 810 Cell 136, March 6, 2009 2009 Elsevier Inc.
 

Summary:  parameters under physiolog- ical conditions. They then used xenografts to produce wild-type tumors... Leading Edge Previews 810 Cell 136, March 6, 2009 ©2009 Elsevier Inc. There is a paradox in tumor... and clinical trials. Most tumors require their own blood supply to grow, and once a ...

  

Source: Bautch, Victoria L. - Department of Biology, University of North Carolina at Chapel Hill

 

Collection: Biology and Medicine

 
79 A novel oncolytic adenovirus targeting to telomerase activity in tumor cells with potent
 

Summary:  . Moreover, direct injection of Ad-TERT into two tumor xenograft models resulted in potent antitumoral... implantation. For Figure 6a, the xenografts tumor model were established by subcutaneously injecting 1  106... as tumor volume (mm3 ) ¼ length  width2 /2. For Figure 6b, the ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
80 Multifunctional Micellar Nanomedicine for Cancer Therapy
 

Summary:  (PSMA) to treat prostate tumors (51). In vivo studies in LNCaP xenografts showed overall increased anti-tumor... control, DOXO-SPIO micelles with 0 and 16% surface density of cRGD in subcutaneous A549 tumor xenografts... -small cell lung tumor ...

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine


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81 Anti-Cancer Drugs 1998, 9, pp. 525-530 Research paper
 

Summary:  Damijan Miklavcic,2 Vita Dolzan3 and Gregor Sersa Department of Tumor Biology, Institute of Oncology... . Electrochemotherapy using intratumoral cisplatin adminis- tration was tested on EAT tumors in mice. Mice were treated... resulted in up to 20 days of tumor growth delay. Electrochemotherapy resulted in ...

  

Source: Ljubljana, University of - Faculty of Electrical Engineering, Laboratory of Biocybernetics

 

Collection: Engineering ; Biology and Medicine

 
82 Dynamic Fluorescence Imaging For The Detection of Vascular Changes in Anti-Angiogenic Drug Therapy
 

Summary:  Xenografts: In vivo Changes of Tumor Blood Volume in Response to Experimental VEGFR Tyrosine Kinase Inhibitor... endothelial growth factor signaling inhibitor AZD2171 in Calu!6 human lung tumor xenografts," Molecular Cancer... OCIS codes!"(170.3880) Medical and Biological Imaging; 1. Introduction The ...

  

Source: Hielscher, Andreas - Department of Biomedical Engineering, Columbia University

 

Collection: Engineering ; Biology and Medicine

 
83 let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
 

Summary:  more tumorigenic than SKBR3. Importantly, mammospheric tumor cells from SK-3rd xenografts could... of forming tumors capable of serial transplantation as xenografts (Clarke et al., 2006). Mammospheric Cells... xenografts than in SKBR3 tumors. Transduction of SK-3rd ...

  

Source: Lieberman, Judy - Immune Disease Institute, Harvard University

 

Collection: Biology and Medicine

 
84 Targeting breast cancer stem cells: Fishing season open! Christophe Ginestier, Emmanuelle Charafe-Jauffret, and Daniel Birnbaum
 

Summary:  were able to specifically target the CSC population in human breast cancer xenografts, retarding tumor... in vivo using breast cancer cell line xenografts, with a decrease in tumor growth and metastasis formation... primary tumor xenografts as a preclinical step. ...

  

Source: Paris-Sud XI, Université de - Institut d'Optique, Laboratoire Charles-Fabry, Groupe d'Optique Atomique

 

Collection: Physics

 
85 In vivo Off-Resonance Saturation Magnetic Resonance Imaging of AvB3-Targeted Superparamagnetic Nanoparticles
 

Summary:  microvasculature in A549 non­small cell lung tumor xenografts in mice. ORS greatly improved tumor detection... tumor xenograft in a mouse. A, ORS and T2*-w images of the transverse section of a representative mouse... bearing two tumor ...

  

Source: Gao, Jinming - Department of Oncology and Pharmacology, University of Texas Southwestern Medical Center at Dallas

 

Collection: Biology and Medicine

 
86 Accumulation of driver and passenger mutations during tumor progression
 

Summary:  Accumulation of driver and passenger mutations during tumor progression Ivana Bozica,b , Tibor... model tumors as a discrete time branching process that starts with a single driver mutation and proceeds... observe tremendous variation in the rate of tumor development--providing an understanding

  

Source: Nowak, Martin A. - Department of Organismic and Evolutionary Biology, Harvard University

 

Collection: Environmental Sciences and Ecology

 
87 Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission
 

Summary:  with initial applications imaging xenograft tumors27 and whole unsectioned rodent organs. In this paper, we... and function, as demonstrated here in relation to xenograft tumor imaging. 2.1 Imaging Hardware and Acquisition... in HCT116 tumor xenografts. The HCT116 ...

  

Source: Rockey, Don - Department of Cell Biology, Duke University

 

Collection: Biology and Medicine

 
88 Complete Elimination of Colorectal Tumor Xenograft by Combined Manganese Superoxide Dismutase with Tumor Necrosis Factor
 

Summary:  Complete Elimination of Colorectal Tumor Xenograft by Combined Manganese Superoxide Dismutase... tumor xenografts were completely eliminated in nude mice. The evidence exists that the Mn... , our dual gene virotherapy completely eliminated colorectal tumor xenografts ...

  

Source: Tian, Weidong - Institute of Biochemistry and Cell Biology, Shanghai Institute of Biological Sciences

 

Collection: Biology and Medicine

 
89 Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies
 

Summary:  -- SKBR3 Breast -- 4.8 ± 1.0 -- 34 ± 6 A-431 Epidermoid 13 ± 2 -- 223 ± 10 82 ± 18 H1437 Lung 27 ± 3 -- 61... implicated in cell proliferation and in resistance of solid tumors to chemotherapy. We quantified ligand... - and heparin-binding EGF-like growth factor. These growth factors are frequently secreted by pan- creatic ...

  

Source: Maoz, Shahar - Department of Computer Science and Applied Mathematics, Weizmann Institute of Science

 

Collection: Computer Technologies and Information Sciences

 
90 Cancer Cell LZAP, a Putative Tumor Suppressor,
 

Summary:  cellular transformation. In vivo studies revealed that diminished LZAP levels enhanced xenograft tumor... Xenograft Tumor Formation To further explore a potential role of LZAP as a tumor suppressor, nude mice... until the largest tumor diameter approached 15 mm ...

  

Source: Hardy, Christopher R. - Biology Department, Millersville University

 

Collection: Environmental Sciences and Ecology

 
91 Imaging, Diagnosis, Prognosis Near IR Heptamethine Cyanine DyeMediated
 

Summary:  -148 were investigated for their ability to accumulate in human cancer cells, tumor xenografts... but not normal cells, in tumor xenografts, and in spontaneous tumors in transgenic mice. They can be used... cells and tumor xenografts Human cancer ...

  

Source: Cheng, Jianjun - Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign

 

Collection: Materials Science

 
92 High resolution vital fluorescence imaging and analysis of tumor microanatomy for surgical margin assessment Jenna Mueller1, Zachary Harmany2, Jeff Mito3, Stephanie Kennedy1, Yongbaek Kim4, Joseph Geradts5, David Kirsch3, Rebecca Willett2, NimmiRamanujam1
 

Summary:  ) Farkas et al3 DAPI Fluorescence microscopy Ex vivo rat mammary tumor xenografts Watershed algorithm... High resolution vital fluorescence imaging and analysis of tumor microanatomy for surgical margin... -1-0410. Results: Experimental in vivo images Figure 4. Extracted versus expected endpoints from tumor and ...

  

Source: Ramanujam, Nimmi - Department of Biomedical Engineering, Duke University

 

Collection: Engineering ; Biology and Medicine

 
93 Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth
 

Summary:  in a xenograft mouse model. Mice seem to remain tumor-free for at least 2 months after combinatorial therapy... modestly inhibits tumor growth of xenografts of a triple-negative breast cancer cell line that lacks... tumors in xenografts (14). MDA-MB-468 cells are ...

  

Source: 

 

Collection: Biology and Medicine

 
94 In Vivo Evaluation of Pretargeted 64Cu for Tumor Imaging and Therapy
 

Summary:  uptake, resulted in a 2-fold more efficient delivery of 64Cu to SW1222 tumor xenografts. This increase... tumor xenografts. Tumor Targeting. 1996;2:156­157. 12. Nakamoto Y, Saga T, Sakahara H, et al. Three... In Vivo Evaluation of Pretargeted 64Cu for Tumor Imaging ...

  

Source: Anderson, Carolyn J. - Department of Molecular Biology and Pharmacology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
95 Research Article Epithelial Phenotype Confers Resistance of Ovarian Cancer
 

Summary:  /TRAIL into mice bearing subcutaneous ovc316 xenografts had no effect on tumor growth compared with PBS... xenograft tumors and on cultured ovc316 cells from passages 1 and 20 (Fig. 4B). In xenografts, the vast... .aacrjournals.org #12;Figure 4. Analysis of ovc316 ...

  

Source: Hemminki, Akseli - Department of Biosciences, University of Helsinki

 

Collection: Biology and Medicine

 
96 Optimization of tumor virotherapy with recombinant measles viruses
 

Summary:  for the growth of myeloma tumor xenografts implanted in immunocompromised mice and treated with a recombinant... the experimentally tested tumor xenografts with a therapeu- tically achievable dose of virus. Our analysis suggests... Optimization of tumor virotherapy with recombinant ...

  

Source: Josic, Kresimir - Department of Mathematics, University of Houston

 

Collection: Mathematics

 
97 Proc. Natl. Acad. Sci. USA Vol. 93, pp. 68146818, June 1996
 

Summary:  cancer xenografts were propagated in 7- to 9-week-old male Golden Syrian hamsters (26). Tumor cell... killed 6­7 months after therapy or when tumors were >10 g. Of the hamsters with small tumors (mean weight... -BAT-2IT-1A3 or 0.4 mCi of 67 Cu- BAT-2IT-1A3. The mean tumor doses at ...

  

Source: Anderson, Carolyn J. - Department of Molecular Biology and Pharmacology, Washington University in St. Louis

 

Collection: Biology and Medicine

 
98 The FASEB Journal express article 10.1096/fj.03-0271fje.Published online December 4, 2003. Combined inhibition of VEGF-and PDGF-signaling en-
 

Summary:  microvasculature of C6 #12;tumor xenografts. We show that VEGFR-2 targeting results in activation of endothelial... inhibition of VEGF- and PDGF-signaling en- forces tumor vessel regression by interfering with pericyte... of existing tumor blood vessels may be achieved by targeting vascular endothelial ...

  

Source: Ullrich, Axel - Max-Planck-Institut für Biochemie

 

Collection: Biology and Medicine

 
99 Ultrasound biomicroscopy permits in vivo
 

Summary:  Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors Wolfram... that tumors could be readily detected in vivo using high-resolution microscopic ultrasound in zebrafish. We... successfully obtained tissue perfusion calculations and cellular aspirates, and analyzed tumor progression

  

Source: Harvard University, North and Goessling Labs

 

Collection: Biology and Medicine

 
100 Mnard. Reptin silencing blocks liver cancer progression 1 In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in
 

Summary:  of senescence-associated heterochromatin foci. In xenografted mice, R2+Dox tumor growth stagnated or even... of primers are in Table 2. For use in xenografted tumors, they were designed, and verified, to be human... growth in xenografts. To test if Reptin expression is necessary for ...

  

Source: Ecole Polytechnique, Centre de mathématiques

 

Collection: Mathematics


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