| Sample search results for: 5-ht3 antagonist tropisetron |
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| 1 | Increased 5-HT3-mediated signalling in pelvic afferent neurons from mice deficient in P2X2 and/or P2X3 | ||
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Summary: -/- compared to the wildtype, the effect of the 5-HT3 receptor antagonist tropisetron on the nerve response... , a 5-HT3 receptor antagonist. The percentage of DRG neurons responding to 5-HT was ... |
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Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London |
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Collection: Biology and Medicine |
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| 2 | Characterizing Ligand-Gated Ion Channel Receptors with Genetically Encoded Ca++ | ||
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Summary: [26]. Since antagonists, such as tropisetron, for the 5-HT3A receptor are known to activate a7- n... indicates that MLA is not solely a competitive antagonist at the a7/5-HT3A CNiFERs (Figure 4b). ... |
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Source: Kleinfeld, David - Computational Neuroscience Group, Department of Physics, University of California at San Diego |
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Collection: Biology and Medicine |
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| 3 | the source of some confusion. The funnel fill, by its very nature, is open | ||
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Summary: tropisetron elimination due to CYP2D6 dupli- cation (2), available data suggest a lesser effect of CYP2D6... metabolizer status on hydrodolasetron kinetics compared with tropisetron (3). While they also cite, to support... reported that there was no difference in tropisetron plasma concentrations in the ultra- rapid metabolizers |
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Source: Steinbach, Joe Henry - Washington University Pain Center & Department of Anesthesiology, Washington University in St. Louis |
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Collection: Biology and Medicine |
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| 4 | Cellular/Molecular The Largest Group of Superficial Neocortical GABAergic | ||
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Summary: NFS3, n 1). Bath application of tropisetron (10 nM), a 5-HT3AR specific antagonist, completely blocked... -hydroxytryptamine 3A (5-HT3A ) receptor, the only ionotropic serotonergic receptor, is expressed in most, if not all... ... |
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Source: Fishell, Gordon - Skirball Institute of Biomolecular Medicine & Department of Cell Biology, New York University |
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Collection: Biology and Medicine |
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| 5 | Cellular/Molecular Uropathic Observations in Mice Expressing a Constitutively | ||
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Summary: levelistypicalofresponsesfromboththeWTandmutantinthepresenceof100nM tropisetron, a 5-HT3 receptor antagonist. B, Normalized dose... in the 5-HT3A Receptor Subunit Anindya Bhattacharya,1 Hong Dang,2 Quan-Ming Zhu,1 Birthe ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 6 | ORIGINAL PAPER J. DeGabriel W.J. Foley I.R. Wallis | ||
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Summary: to the third hypothesis, the 5HT3 receptor antagonist, ondansetron, did not affect feeding by possums given... excess Met Use of ondansetron as an antagonist of the 5HT3 receptor. Basal diet containing 0.8% WM Met 4... 3: the ... |
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Source: Foley, Bill - School of Botany and Zoology, Australian National University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 7 | Introduction Chapter 1 1 Introduction | ||
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Summary: ; however, the receptors were not susceptible to blockade by selective 5-HT2 and 5-HT3 antagonists19... by methiothepin and/or methysergide, resistance to 5-HT2 and 5-HT3 antagonists and potent agonism by 5-CT... ]Mesulergine ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 8 | Psychopharmacology (1997) 130 : 242248 Springer-Verlag 1997 ORIGINAL INVESTIGATION | ||
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Summary: that it is blocked by 5-HT3 antagonists (Chen et al. 1991; Campbell and McBride 1994). Materials and methods Subjects... . For the experiments evaluating the abil- ity of the 5-HT3 antagonist, ICS 205930, to inhibit DA ... |
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Source: Matell, Matthew S. - Department of Psychology, Villanova University |
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Collection: Biology and Medicine |
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| 9 | Ecology, 86(11), 2005, pp. 29462954 2005 by the Ecological Society of America | ||
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Summary: of the serotonin re- ceptor (5-HT3) antagonist, ondansetron, did not affect food intake. But, ondansetron did... , and B. M. Eschler. 1998. Administration of a 5HT3 receptor antagonist increases the intake of diets... . ... |
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Source: Foley, Bill - School of Botany and Zoology, Australian National University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 10 | Serotonin is a biogenic amine that activates a large and heterogeneous family of receptors that are widely | ||
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Summary: -application of the 5-HT3-selective competitive antagonist MDL72222 (IC50 96 nM; n = 6), confirming that the serotonin... & Yakel, 1995). The 5-hydroxytryptamine type 3 (5-HT3) receptor was first defined pharmacologically... receptor family ... |
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Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University |
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Collection: Biology and Medicine |
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| 11 | TheJournalofGeneralPhysiology A RT I C L E | ||
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Summary: mode antagonists. Picrotoxin inhibits 5-HT3A and GABAA receptors (Das et al., 2003). At GABAA receptors... 4 by 80 ± 4% (n = 6) and 79 ± 2% (n = 6), respectively. Ondansetron, a 5-HT3A competitive antagonist... :2250222507. ... |
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Source: Akabas, Myles - Department of Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University |
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Collection: Biology and Medicine |
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| 12 | Distinct subcellular targeting of uorescent nicotinic a3b4 and serotoninergic 5-HT3A receptors in | ||
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Summary: antagonist speci®c for the 5-HT3AR (GR-rho; see Material and Methods). By combining triple ¯uorescence we... Distinct subcellular targeting of ¯uorescent nicotinic a3b4 and serotoninergic 5-HT3A receptors... , receptors, serotoninergic, ... |
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Source: Cossart, Rosa - Institut de Neurobiologie de la Méditerranée, Inserm |
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Collection: Biology and Medicine |
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| 13 | Pharmacological Strategies for Enhancing Cognition in Schizophrenia | ||
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Summary: ), which is a strong 5-HT3 antagonist that is also a high-affinity partial agonist for a7 nicotinic... Antagonists ........................................................ 66 4 Gamma-Aminobutyric Acid Modulating... - A is an a7-selective partial agonist, though at higher doses it is also a ... |
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Source: Washington University in St. Louis, Department of Psychology, Cognitive Control and Psychopathology Laboratory |
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Collection: Biology and Medicine |
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| 14 | A Hydrogen Bond in Loop A Is Critical for the Binding and Function of the 5-HT3 Kerry L. Price, | ||
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Summary: . Data are means ( the standard error of the mean (n ) 3-6). FIGURE 7: Antagonist binding to 5-HT3... an antagonist in the 5-HT3 receptor binding site using modeling and radioligand binding. J. Biol. Chem. 280... A Hydrogen ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 15 | Cellular/Molecular A Role for the 1 2 Loop in the Gating of 5-HT3 Receptors | ||
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Summary: - tinic acetylcholine receptors (AChR). 5-HT3R antagonists are used clinically for the prevention... Cellular/Molecular A Role for the 1 2 Loop in the Gating of 5-HT3 Receptors David C. Reeves,1... positions in the ... |
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Source: Akabas, Myles - Department of Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University |
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Collection: Biology and Medicine |
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| 16 | Subscriber access provided by CASE WESTERN RESERVE UNIV Biochemistry is published by the American Chemical Society. 1155 Sixteenth | ||
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Summary: , 1-piperidinylethyl-1H-indole-3- carboxylate; Tropisetron, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3... the tissue harvesting campaigns. In ViVo Antagonist Treatments. Lactating mice with 1-week-old pups were... provided with drinking water contain- ing 10 µM 5HT4R antagonist RS39604 for 2 weeks. Pups were sacrificed |
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Source: Palczewski, Krzysztof - Department of Pharmacology, Case Western Reserve University |
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Collection: Biology and Medicine |
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| 17 | Cellular/Molecular Tyrosine Residues That Control Binding and Gating in the | ||
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Summary: al. · Tyrosines in the 5-HT3 Receptor Binding Site #12;143, however, is not essential for antagonist... , and Tyr234), which dominate the 5-HT3 receptor binding site. Heterologous expression in oocytes, combined... ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 18 | Monitoring Expression and Clustering of the Ionotropic 5HT3 Receptor in Plasma Membranes of Live Biological Cells | ||
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Summary: structure of the ligands that were used. The 5HT3R-specific antagonist GR119566 (X ) H or GR-H) was labeled... Monitoring Expression and Clustering of the Ionotropic 5HT3 Receptor in Plasma Membranes of Live... , the short splicing variant of the ... |
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Source: Mayer, Michael - Biomedical Engineering Program & Department of Chemical Engineering, University of Michigan |
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Collection: Biology and Medicine ; Materials Science ; Engineering |
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| 19 | Integrated HighIntegrated High--Throughput Virtual andThroughput Virtual and Experimental Screening:Experimental Screening | ||
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Summary: -2217 chart 1 N N O N N O A-85380: incorrect ring size -||- & JMC 36- 2645 NN O O O N N O tropisetron: methyl... antagonist T.I. Oprea & H. Matter, Curr. Opin. Chem. Biol., 2004, 8, in press #12;Good Virtual Screening... NH2 NH CH3 N H O 4.A. Calcium antagonist 4.B. GSK-3 inhibitor 4.C. VLA-4/VCAM-1 ... |
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Source: Oprea,Tudor I. - Department of Biochemistry and Molecular Biology, University of New Mexico |
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Collection: Biology and Medicine |
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| 20 | Serotonin elicits long-lasting enhancement of rhythmic respiratory activity in turtle brain stems in vitro | ||
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Summary: the original baseline for 40 min (P 0.05) and remained above baseline for 2 h. A 5-HT3 antagonist (tropesitron... agonist), 3-tropanyl-indole-3- carboxylate hydrochloride (tropesitron, 5-HT3 antagonist). Data Analysis... of ... |
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Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 21 | Pharmacological characterization of serotonin receptor subtypes modulating primary aerent input to deep dorsal horn neurons in | ||
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Summary: 7 receptor antagonist clozapine. 4 Agonists for the 5-HT1B, 5-HT2 and 5-HT3 receptors exerted only... -(m- chlorophenyl)-biguanide (CPBG), a 5-HT3 receptor agonist. The eective 5-HT receptor antagonists... of these ... |
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Source: Hochman, Shawn - Department of Physiology, Emory University |
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Collection: Biology and Medicine |
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| 22 | Research paper Transient gain adjustment in the inferior colliculus is serotonin-and | ||
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Summary: or reduced by an antagonist to ionotropic serotonin receptors (5-HT3R). Block- ing voltage-activated calcium... neurons contained a serotonergic component, a 5-HT3 receptor antagonist (LY-278, 584 at 1 lM) was added... ... |
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Source: Sanes, Dan H.- Center for Neural Science, New York University |
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Collection: Biology and Medicine |
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| 23 | Principal Investigator/Program Director (Last, First, Middle): Hodge, Clyde W. PHS 398/2590 (Rev. 09/04) Page Biographical Sketch Format Page | ||
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Summary: is required for 5-HT3 antagonist-induced reductions in alcohol drinking. Neuropsychopharmacology 29... . Targeted gene deletion of the 5-HT3A receptor subunit produces an anxiolytic phenotype in mice. European... . Psychopharmacology 174:358 366; ... |
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Source: Elston, Timothy C. - Department of Pharmacology, University of North Carolina at Chapel Hill |
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Collection: Mathematics ; Biology and Medicine |
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| 24 | Localization of 5-HT2A, 5-HT3, 5-HT5A and 5-HT7 receptor-like immunoreactivity in the rat cerebellum | ||
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Summary: Localization of 5-HT2A, 5-HT3, 5-HT5A and 5-HT7 receptor-like immunoreactivity in the rat... in this part of the brain remains fragmentary. In this study, we report the presence and distribution of 5-HT3... histochemistry. ... |
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Source: De Schutter, Erik - Born-Bunge Foundation, Universiteit Antwerpen |
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Collection: Computer Technologies and Information Sciences ; Biology and Medicine |
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| 25 | The treatment of cognitive impairment in schizophrenia Donald C. Goff, Michele Hill, Deanna Barch | ||
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Summary: .g., dopamine agonists and NMDA receptor antagonists), receptor abnormalities found on postmortem analysis... ) and the reduction in levels of the endogenous glycine site antagonist, kynurenic acid, by enzymatic inhibitors... is complicated, however, by the recent finding that the nonselective GABAA antagonist (inverse agonist |
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Source: Washington University in St. Louis, Department of Psychology, Cognitive Control and Psychopathology Laboratory |
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Collection: Biology and Medicine |
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| 26 | Vol 438|10 November 2005 NEWS & VIEWS | ||
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Summary: . In addition, the apparent affinity of the 5-HT3 receptor competitive antagonist MDL72222 is not significantly... the activationpathwayinvolvedinthiscoupling(Arg,Glu,Pro).Lummiset al.3 foundthattheprolineresidue at the same position in the serotonin ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 27 | 5-HT Receptors and the Neuromodulatory Control of | ||
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Summary: ............................................................................................................... 7 2.2.3 5-HT3 receptors... information in neurons by activation of serotonergic 5-HT1 and 5-HT3 receptors [30-32]. Conversely... ), and the ... |
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Source: Hochman, Shawn - Department of Physiology, Emory University |
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Collection: Biology and Medicine |
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| 28 | letters to nature 470 NATURE |VOL 408 |23 NOVEMBER 2000 |www.nature.com | ||
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Summary: but not of cations. The MOD-1 channel is not blocked by calcium ions or 5-HT3a-speci®c antagonists but is inhibited... antagonists of the 5-HT3a channel18 , did not affect the action of 5-HT on MOD-1 channels. Pretreatment... ... |
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Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT) |
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Collection: Biology and Medicine |
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| 29 | Neuropharmacology of alcohol addiction V Vengeliene, A Bilbao, A Molander and R Spanagel | ||
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Summary: -preferring counterpart lines (McBride and Li, 1998). In agreement, 5-HT3 receptor antagonists were shown to suppress... reuptake inhibitors, 5-HT1, 5-HT2 and 5-HT3 agonists as well as antagonists were capable of reducing... ... |
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Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health, |
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Collection: Computer Technologies and Information Sciences ; Biology and Medicine |
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| 30 | Allosteric Modulation of 2-Adrenergic Receptor by Zn2 GAYATHRI SWAMINATH, JACQUELINE STEENHUIS, BRIAN KOBILKA, and TAE WEON LEE | ||
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Summary: Sci USA 94:1338613387. Hubbard PC and Lummis SC (2000) Zn2 enhancement of the recombinant 5-HT(3... and Bmax values for the antagonist dihydroalprenolol (DHA). These results demonstrate that Zn2... previously (Kobilka, 1995). Membrane Binding Assays. Antagonist binding assays were done ... |
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Source: Kobilka, Brian - Department of Molecular and Cellular Physiology, Stanford University |
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Collection: Biology and Medicine |
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| 31 | 2001 Wiley-Liss, Inc. DRUG DEVELOPMENT RESEARCH 53:281291 (2001) | ||
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Summary: -4), histamine (H1), serotonin (5-HT3) or adenosine (A1 and A2B) receptors [Lambrecht et al., 1992, 2000; Boyer... can be altered at the pyridoxal and phenyl moieties to produce P2X1 and P2X3 receptor antagonists... ; ion channel; nucleotide; ATP; antagonist Strategy, Management and Health ... |
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Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London |
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Collection: Biology and Medicine |
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| 32 | Cellular/Molecular A Cation-Interaction in the Binding Site of the Glycine | ||
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Summary: ) The antimalarial drugs quinine, chloro- quine and mefloquine are antagonists at 5-HT3 receptors. Br J Pharmacol 151... :666667. Thompson AJ, Price KL, Reeves DC, Chan SL, Chau PL, Lummis SCR (2005) Locating an antagonist in the ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 33 | ORIGINAL PAPER I. R. Lawler W. J. Foley G. J. Pass B. M. Eschler | ||
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Summary: injected (0.5 mg á kgA0.75 body mass) with ondan- setron (a selective antagonist of serotonin 5HT3 recep... by sero- tonin. Because ondansetron is such a selective antagonist of serotonin 5HT3 receptors (Butler et... also ... |
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Source: Foley, Bill - School of Botany and Zoology, Australian National University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 34 | Ann. N.Y. Acad. Sci. ISSN 0077-8923 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES | ||
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Summary: bicuculline/picrotoxin-sensitive glycine ( 1, 2, ), nicotinic ( 9, 10), GABAA-rho, or 5HT3A recep- tor... subunits. GABAA, glycine, ACh nicotinic, and 5-HT3 receptors all comprise the Cys-loop family... HT3, and glycine ... |
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Source: Hochman, Shawn - Department of Physiology, Emory University |
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Collection: Biology and Medicine |
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| 35 | The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using | ||
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Summary: Bride, W.J., Lumeng, L., Li, T.K., 2000. Effects of 5-HT(3) receptor antagonists on daily alcohol intake... selective pharmacological agents: the NMDAR competitive antagonist CGP37849, the glycine binding site... antagonist L-701.324, the NR2B subunit selective ... |
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Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health, |
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Collection: Computer Technologies and Information Sciences ; Biology and Medicine |
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| 36 | Ligand Gated Ion Channel Functionality Assays Robert P. Hayes, Kumud Raj Poudel and James A. Brozik | ||
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Summary: Serotonin Receptor (5HT3a) 2 SDS-PAGE Results 3 Structure of Biomimetic Assembly 4 Experimental Methods 5... through a cell membrane. In this project, the human type 3 serotonin receptor ion channel (5HT3a... kidney cells. The presence of the ... |
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Source: Collins, Gary S. - Department of Physics and Astronomy, Washington State University |
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Collection: Physics |
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| 37 | 94:1392-1404, 2005. First published May 4, 2005; doi:10.1152/jn.00136.2005JN Jun Liu and Larry M. Jordan | ||
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Summary: -HT3 Receptor Agonist-Induced Motor Responses in the Hindlimbs of including high-resolution figures... ][Abstract] , November 1, 2005; 94 (5): 3397-3405.J Neurophysiol P. A. Guertin and I. Steuer Paraplegic Mice Ionotropic 5... or chemical stimulation, and PPR-evoked locomotor-like activity was blocked by ... |
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Source: Manitoba, University of - Spinal Cord Research Centre |
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Collection: Biology and Medicine |
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| 38 | Targeting Cell Surface Receptors with Ligand-Conjugated Nanocrystals | ||
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Summary: indicated that LSNACs did not elicit currents from the serotonin-3 (5HT3) receptor but did produce currents... . Plasmids (pBluescript-SKII) containing the human serotonin receptor 5HT3 or hSERT cDNA were linearized... and VI oocytes were harvested, defolliculated, ... |
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Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 39 | The relevance of the serotonergic system in depression The relevance of the serotonergic system in | ||
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Summary: , substantia gelatinosa and nuclei of the lower brain stem. Centrally active 5-HT3 antagonists have been... antagonists (Barnes et al. 1992). In ventral hippocampus, local infusion of 5-HT3 antagonist MDL ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 40 | THESE PRESENTEE A L'UNIVERSITE D' ORLEANS POUR OBTENIR LE GRADE DE | ||
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Summary: tropisetron. En conclusion, le rôle des sites 5-HT3 n'est pas véritablement élucidé et il apparaît évident que... antiémétiques (les antagonistes des récepteurs 5-HT3 comme l'ondansétron et le granisetron). Les ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 41 | 2006 Nature Publishing Group Modern imaging has transformed practice in the clinical | ||
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Summary: tropisetron. En conclusion, le rôle des sites 5-HT3 n'est pas véritablement élucidé et il apparaît évident que... antiémétiques (les antagonistes des récepteurs 5-HT3 comme l'ondansétron et le granisetron). Les ... |
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Source: Maeda, Fumiko - Center for Interdisciplinary Brain Sciences Research, Stanford University |
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Collection: Biology and Medicine |
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| 42 | Bren Professor of Biology: Henry A. Lester George Grant Hoag Professor Chemistry: Dennis | ||
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Summary: -gated channels, the nicotinic 4 receptor and the serotonin 5-HT3 receptor. The nicotinic receptor work... addiction, neurodegenerative disease, and epilepsy. The 5-HT3 receptor studies have generated insights... , and modulation of sensorimotor gating in knock-in mice ... |
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Source: Elowitz, Michael - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 43 | Medical Management of Radiation Accidents: Management of the Acute Radiation 2001 The British Institute of Radiology | ||
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Summary: irradiation (TBI) Triage #12;xi 5-HT3 ARDS ARS ATG BMSCT BP C CAMPATH 1H CCI CNS CRP CS CT/CCT CTZ EC EEG ENT |
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Source: Pfeifer, Holger - Institut für Künstliche Intelligenz, Universität Ulm |
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Collection: Computer Technologies and Information Sciences |
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| 44 | Topical differences in serotonergic autoreceptor control; effects of chronic treatment with citalopram Topical differences in serotonergic autoreceptor | ||
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Summary: uptake, 5-HT1B autoreceptors, 5-HT3 and 5-HT4 receptors in rats. Naunyn Schmiedebergs Arch Pharmacol, 356... with the 5-HT1A receptor antagonist Way 100635 or the 5-HT1B/D receptor antagonist GR 127935 were used... several research groups to propose that co-administration of SSRIs with a ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 45 | The University of New Mexico Health Sciences Center SCHOOL OF MEDICINE | ||
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Summary: tropisetron: methyl group in plus -||- N N N O N O O N O N ON O DAU-6285: missing methoxy; N instead O JMC 37... .S. Tasker et al., J. Med. Chem. 40, 1997, 322-330 endothelin antagonists SID_460: T. Su, et al., J. Med... . Chem. 40, 1997, 4308-4318 fibrinogen (GP IIb/IIIa) antagonists SID_1563_2: A. Scozzafava et al., J |
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Source: Oprea,Tudor I. - Department of Biochemistry and Molecular Biology, University of New Mexico |
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Collection: Biology and Medicine |
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| 46 | Stimulating electrode AMPA receptor | ||
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Summary: with conductances which cause changes Noncompetitive antagonist = picrotoxin Competitive antagonist = bicuculline... GABAB receptor Agonist = baclofen Antagonist = phaclofen Antagonist = 2-amino-5-phosphonovaleric acid... (AP5 or APV) Antagonist = 6-cyano-7-nitro-quinoxaline- (CNQX) ... |
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Source: Hasselmo, Michael - Department of Psychology & Computational Neurophysiology Laboratory, Boston University |
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Collection: Biology and Medicine |
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| 47 | Cys-loop receptors: new twists and turns | ||
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Summary: receptor Cations $ 16 5-HT 5-HT3 receptor Cations $ 2 GABA GABAA receptor Anions $ 19 Glycine Glycine... examined (the ACh receptor, the 5-HT3 receptor Table 2. Medical aspects of Cys-loop receptor defectsa... ] Insecticidal effects ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 48 | Cellular/Molecular Unnatural Amino Acid Mutagenesis of the GABAA Receptor | ||
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Summary: -loop ligand-gated ion channel family, which includes nicotinic acetylcholine (nACh), glycine, and 5-HT3... on the neurotransmitter and an aromatic residue on loop B in the nACh receptor (Zhong et al., 1998), the 5-HT3 receptor... the alignment of both ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 49 | Augmentation of the Neurochemical and Behavioural Effects of SSRIs | ||
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Summary: binds with only modest affinity. MDL 72222 was the first selective 5-HT3 antagonist. It is a structural... -HT6, and 5- HT7 receptors are G-protein-coupled receptors (GPCRs), whereas the 5-HT3 receptors... phosphates (Niswender et al, 1998: ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 50 | SSRI augmentation strategies; pharmacodynamic and pharmacokinetic | ||
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Summary: , substantia gelatinosa and nuclei of the lower brain stem. Centrally active 5-HT3 antagonists have been... antagonists (Barnes et al. 1992). In ventral hippocampus, local infusion of 5-HT3 antagonist MDL ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 51 | Journal of Physiology (1991). 442, pp. 235-255 235 Wtith 8 figures | ||
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Summary: and ritanserin, but not by the 5-HTlA antagonist pindolol or the 5-HT3 antagonist ICS 205-930. Furthermore, the 5... and ritanserin and not blocked by the 5-HTlA/5-HTlB antagonist pindolol or the 5-HT3 ... |
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Source: McCormick, David - Department of Neurobiology, Yale University |
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Collection: Biology and Medicine |
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| 52 | Stimulation of cortical acetylcholine release following blockade of ionotropic glutamate receptors in nucleus | ||
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Summary: forebrain by physostigmine and nicotine but not by the 5-HT3 receptor antagonist, ondansetron... of the broad spectrum ionotropic glutamate receptor antagonist kynurentate (1.0, 5.0 mM) led to a dose... with the intra-accumbens perfusion of the AMPA/kainate ... |
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Source: Bruno, John P. - Department of Psychology, Ohio State University |
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Collection: Biology and Medicine |
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| 53 | Hallucinogen-like actions of 5-methoxy-N,N-diisopropyltryptamine in mice and rats | ||
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Summary: in the amount of radioligand binding in the absence and presence of either 10 M 5-HT ([3 H]8-OH- DPAT binding... ), 20 M 5-HT ([3 H]mesulergine binding) or 100 M cinanserin ([3 H]ketanserin binding). 2.4. Data... ) and challenged with the selective serotonin (5-HT)2A ... |
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Source: Howell, Leonard L. - Yerkes National Primate Research Center, Emory University |
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Collection: Biology and Medicine |
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| 54 | Galantamine Is an Allosterically Potentiating Ligand of Neuronal Nicotinic but Not of Muscarinic Acetylcholine | ||
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Summary: of mouse 5-HT3 receptor was kindly provided by Drs. H. Hatt and G. Gisselmann (Institute of Animal... into the expression vector pcDNA3 (Invitro- gen, San Diego, CA). The 7/5-HT3 chimera was cloned into the inducible... vector pcDNA4/TO. All constructs were ... |
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Source: Lübbert, Hermann - Fakultät für Biologie, Ruhr-Universität Bochum |
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Collection: Biology and Medicine |
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| 55 | The serotonergic system The Serotonergic System | ||
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Summary: binds with only modest affinity. MDL 72222 was the first selective 5-HT3 antagonist. It is a structural... -HT6, and 5- HT7 receptors are G-protein-coupled receptors (GPCRs), whereas the 5-HT3 receptors... phosphates (Niswender et al, 1998: ... |
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Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 56 | Brain Research 932 (2002) 9198 www.elsevier.com/locate/bres | ||
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Summary: 1152. As in the CNS of vertebrates, the expression of 5-HT [3] B.S. Beltz, E.A. Kravitz, Mapping of serotonin... receptor3 2 classification. We examined this possibility by using a selective agonist and two antagonists... of the vertebrate 5-HT receptor subtypes.2 The antagonist ... |
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Source: Cooper, Robin L. - Department of Biology, University of Kentucky |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 57 | BI-DIRECTIONAL MODULATION OF BED NUCLEUS OF STRIA TERMINALIS NEURONS BY 5-HT: MOLECULAR EXPRESSION AND | ||
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Summary: 545 5-HT1A NM_012585 336 5-HT3 U59672 415 5-HT1B M89954 200 5-HT4 AJ011370 610 5-HT1D M89953 367 5-HT5... , and consistently included transcripts for 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, 5-HT2A, 5-HT2C, 5-HT3, 5-HT4 5-HT5A, 5-HT... neurons. We reasoned that the ... |
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Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University |
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Collection: Biology and Medicine |
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| 58 | Behavioral Neuroscience 1996, Vol. 110, No. 2, 368-388 | ||
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Summary: ) was challenged by the intrathecal administration of receptor antagonists to serotonin (methysergide... in reversing increases in SMR thresholds. The efficacy of these antagonists to reduce increases in VDS and VAD... in the thresholds ofsupraspinally organized behaviors are only briefly attenuated by IT- administered ... |
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Source: Borszcz, George S. - Department of Psychology, Wayne State University |
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Collection: Biology and Medicine |
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| 59 | Mapping convulsants' binding to the GABA-A receptor chloride ionophore: A proposed model for channel binding sites | ||
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Summary: (5-HT3) and N-acetylcholine receptors by GABA-A channel blockers, and examine the applicability... --GABA receptors of invertebrates, N- acetylcholine, glycine, glutamate, and serotonin (5-HT3) receptors (Ffrench... GABA Yes Yes Yes Yes Acetylcholine N-type Yes ... |
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Source: Kalueff, Allan V. - Department of Pharmacology, Tulane University |
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Collection: Biology and Medicine |
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| 60 | NEUROSYSTEMS Astrocyte-derived kynurenic acid modulates basal and | ||
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Summary: the hypothesis that fluctuations in the levels of kynurenic acid (KYNA), an endogenous antagonist of the a7... to the modulation of a7nAChR function. A non-compet- itive a7nAChR antagonist (Hilmas et al., 2001), KYNA acts... antagonist of a7nAChR Following its irreversible transamination from kynurenine in astrocytes, newly ... |
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Source: Bruno, John P. - Department of Psychology, Ohio State University |
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Collection: Biology and Medicine |
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| 61 | Contribution of Valine 70 Gating of Neuronal a3 Receptor Subtypes | ||
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Summary: , and 5-hydroxitryptamine-3 (5-HT3) receptors. These receptors share a pentameric structure, with each... with nicotine as the agonist. The antagonist sensitivity of the mutant channels was assessed by using dihydro... in antagonist potency were observed for the V70 A and V70 Y mutants. ... |
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Source: Lasalde Dominicc, Jose A. - Department of Biology, Universidad de Puerto Rico - Rio Piedras |
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Collection: Biology and Medicine |
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| 62 | Augmentation strategies to improve the effect of SSRIs in the treatment of depression Augmentation strategies to improve the effect of | ||
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Summary: alleviate gastrointestinal discomfort related to SSRI treatment. 5-HT3 receptors antagonists have recently... and partial agonists and 5-HT2C (but not 5- HT3) receptor antagonists increase rates of punished responding... A ... |
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|
Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 63 | Serotonergic Modulation of Neurotransmission in the Rat Basolateral Amygdala | ||
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Summary: moderate to high levels of binding sites for 5-HT1A, 5-HT2, 5-HT3, 5-HT4, and 5-HT6 receptors (Barnes et al... in the central nu- cleus, whereas 5-HT2, 5-HT3, and 5-HT6 receptors are found predominantly in the basolateral... ). Moreover, expression of ... |
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Source: Rainnie, Donald "Tig" - Yerkes National Primate Research Center, Emory University |
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Collection: Biology and Medicine |
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| 64 | Developmental Changes in the Neurotransmitter Regulation of Correlated Spontaneous Retinal Activity | ||
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Summary: - tinic acetylcholine and serotonin 5-HT3 receptors in developing visual cortex. J Neurosci 17... the charge transferred per minute in the absence and pres- ence of antagonists. Charge transferred... and whole-cell recordings, antagonists to ionotropic glutamate and cholinergic receptors ... |
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Source: Myhr, Karen - Department of Biological Sciences, Wayne State University |
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Collection: Biology and Medicine |
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| 65 | BCP 848R FINAL Revised #3 11/21/06 | ||
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Summary: area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3... , knockout; PS, paradoxical sleep; RH3- agonist, H3-receptor agonist; RH3-antagonist, H3-receptor antagonist... autoinhibition. The role of H3- receptor ... |
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Source: Ecole Polytechnique, Centre de mathématiques |
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Collection: Mathematics |
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| 66 | mGluR5 Antagonist MPEP Reduces Ethanol-Seeking and Relapse Behavior | ||
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Summary: in humans (acamprosate, naltrexone, and 5-HT3-antagonists) also attenuate the ADE (Spanagel and Ho... , McBride WJ et al (2000). Effects of 5-HT(3) receptor antagonists on daily alcohol intake under... mGluR5 ... |
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|
Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health, |
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Collection: Computer Technologies and Information Sciences ; Biology and Medicine |
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| 67 | Alcohol Reinforcement and Voluntary Ethanol Consumption | ||
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Summary: 930 (ICS), a 5-HT3 antagonist, for all seven sessions; (c) 200 mg% ethanol for all seven sessions; or (d... reinforcement and the involvement of the 5-HT3 receptor in the action of ethanol at this site rich in DA neurons... -infusions of GABAA ... |
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Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health, |
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Collection: Computer Technologies and Information Sciences ; Biology and Medicine |
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| 68 | Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus | ||
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Summary: lesions of the cholinergic basal forebrain by physostigmine and nicotine but not by the 5-HT3 receptor... of enhancement of synaptic transmission. The effect was blocked by c-aminobutyric acid (GABA)ergic antagonists... of the nicotinic antagonists mecamylamine and methyllycaconitine. ... |
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Source: Hasselmo, Michael - Department of Psychology & Computational Neurophysiology Laboratory, Boston University |
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Collection: Biology and Medicine |
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| 69 | GABAA Receptor 2 Tyr97 Line the GABA-binding Site | ||
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Summary: for acetylcholine (Torpedo nAChR (21,22,24,55)), benzodiazepines (GABAAR 1 (18 20)), and serotonin (5HT3A (56... AND ANTAGONIST ACTIONS* Received for publication, September 26, 2001, and in revised form, November 8, 2001... , suggesting that binding of a competitive antagonist can cause ... |
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|
Source: Jackson, Meyer B. - Neuroscience Training Program & Department of Physiology, University of Wisconsin at Madison; Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 70 | ORIGINAL PAPER G. J. Pass W. J. Foley | ||
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Summary: and (B) basal diet plus saline. Ondansetron is a potent and highly selective antagonist of 5-HT3... - none in common brushtail possums then dosing the animals with a selective 5-HT3 antagonist should show... selective sero- ... |
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Source: Foley, Bill - School of Botany and Zoology, Australian National University |
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Collection: Environmental Sciences and Ecology ; Biology and Medicine |
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| 71 | ABBREViATiONS: DOB, 1-(4-bromo-2,5-dimethoxy 4-bromoamphetamine; 5-HT, 5-hydroxytryptanune; d-LSD; d-lysergic acid diethylamide; GppNHp, guanosine 5'-(fl,-y-imido)trlphosphate; GTP'yS, guanosine-5'-O-(3-thio)triphosphate; 8-OH-OPAT, 8-hydroxy-2-di-N-propy | ||
|
Summary: -DPAT, the 5-HT18 agent RU 24969, the 5-HT10 agent 5-CT, and the 5-HT3- selective agent ICS 205-930 were... -HT1, 5-HT2, or 5-HT3 binding subtypes because, for example, they display nanomolar affinity for both... for 5-HT1A, 5-HT1B, 5-HT1D, and ... |
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Source: Wang, Samuel S.-H. - Department of Molecular Biology, Princeton University |
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Collection: Biology and Medicine |
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| 72 | Descending control of persistent pain: inhibitory or facilitatory? Horacio Vanegasa,b,*, Hans-Georg Schaibleb | ||
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Summary: the contralateral, uninflamed paw [58]. Conversely, i.th. idazoxan, an a2 adrenoceptor antagonist, enhanced... of either lidocaine or the NMDA receptor (NMDAR) antagonist APV [69]. Furthermore, RVM microinjection... of the neurotensin receptor antagonist SR48692 also attenuated this thermal secondary hyperalgesia [69]. ... |
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Source: Meagher, Mary - Department of Psychology, Texas A&M University |
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Collection: Biology and Medicine |
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| 73 | Unnatural amino acid mutagenesis in mapping ion channel function | ||
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Summary: -hydroxytryptamine 5-HT3AR 5-hydroxytryptamine-3A receptor ACh acetylcholine nAChR nicotinic acetylcholine receptor... and F4-Tyr. Cation-p binding site in nAChR and 5-HT3AR We also used unnatural mutagenesis to investigate... in the serotonin-gated ion channel, ... |
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Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 74 | Specify hypotheses in terms of chemical | ||
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Summary: Identification Using Catalyst v Two 5-HT3 antagonists (green and yellow) mapped on to a six-feature hypothesis |
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Source: Ferreira, Márcia M. C. - Instituto de Química, Universidade Estadual de Campinas |
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Collection: Chemistry |
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| 75 | Microscopic Kinetics and Energetics Distinguish GABAA Receptor Agonists from Antagonists | ||
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Summary: Microscopic Kinetics and Energetics Distinguish GABAA Receptor Agonists from Antagonists Mathew V... , Oregon 97201 USA ABSTRACT Although agonists and competitive antagonists presumably occupy overlapping... channel opening whereas antagonists do not. One explanation is that only agonist binding performs enough |
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|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 76 | Local and Global Ligand-Induced Changes in the Structure of the GABAA Yukiko Muroi, Cynthia Czajkowski, and Meyer B. Jackson* | ||
|
Summary: , the nAChRs, the glycine receptor, and the 5-HT3 receptor, are pentamers composed of homologous subunits... interface. The competitive antagonist SR-95531 inverted this pattern of fluorescence change... , but the noncompetitive antagonist picrotoxin failed to elicit optical signals. In ... |
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|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison; Zhang, Su-Chun - Neuroscience Training Program & Waisman Center, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 77 | Local and Global Ligand-Induced Changes in the Structure of the GABAA Yukiko Muroi, Cynthia Czajkowski, and Meyer B. Jackson* | ||
|
Summary: , the nAChRs, the glycine receptor, and the 5-HT3 receptor, are pentamers composed of homologous subunits... interface. The competitive antagonist SR-95531 inverted this pattern of fluorescence change... , but the noncompetitive antagonist picrotoxin failed to elicit optical signals. In ... |
|||
|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 78 | International Union of Pharmacology. XXIV. Current Status of the Nomenclature and Properties of P2X | ||
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Summary: AMPA 0.09 14 7-Nicotinic 6.620 Seguela et al., 1993; Fucile et al., 2000 5HT3A a 1.08 Davies et al... ., 1999 5HT3A/B a 0.62 AMPA, -amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid; NMDA, N-meth- yl... -D-aspartate. a The value given is pCa2 /pCs , and pNa /pCs ... |
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|
Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London |
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Collection: Biology and Medicine |
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| 79 | Progress in Neurobiology 66 (2002) 355474 Descending control of pain | ||
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Summary: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398 7.4.4. 5-HT3 receptors... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377 5.9.4. NMDA receptor antagonists |
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Source: Meagher, Mary - Department of Psychology, Texas A&M University |
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Collection: Biology and Medicine |
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| 80 | Pharmacological evaluation of selected arylpiperazines with atypical antipsychotic potential | ||
|
Summary: subclasses, but also of 5- HT3, 5-HT6 and 5-HT7 receptors, is indicated in the literature.4;68 Research data... , 5-HT2A, 5-HT2C and 5-HT3) and a1- adrenergic receptors. These receptors were chosen con- cerning... 5-HT1A 5-HT2A 5-HT2C ... |
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|
Source: Champagne, Frances A. - Department of Psychology, Columbia University |
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Collection: Biology and Medicine |
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| 81 | This article was published in an Elsevier journal. The attached copy is furnished to the author for non-commercial research and | ||
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Summary: ] Borea PA, Dalpiaz A, Gessi S, Gilli G. Thermodynamics of 5- HT3 receptor binding discriminates agonistic... , Bernard A, Surprenant A, et al. Ligand binding to the serotonin 5HT3 receptor studied with a novel... M). Furthermore, chronic exposure to the compe- titive ... |
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|
Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 82 | Proc. Natl. Acad. Sci. USA Vol. 95, pp. 1073410739, September 1998 | ||
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Summary: of diverse target receptors (18). These may include 5-HT2A, 5-HT2C, and 5-HT3 receptors, because selective... antagonists acting on these receptors have been suggested to be anxiolytics (18, 21). Because of the role... of presynaptic 5-HT1AR in regulating the 5-HT system, blockade of the receptor by ... |
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|
Source: Sibille, Etienne - Center for the Neural Basis of Cognition & Department of Psychiatry, University of Pittsburgh |
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Collection: Biology and Medicine |
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| 83 | Potential role of N-methyl-D-aspartate receptors as executors of neurodegeneration resulting from diverse insults: focus on | ||
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Summary: this assumption, there are only four plausible targets: the NMDA receptor channel, 5-HT3 receptors... ., 2004; Aracava et al., 2005). Antagonism of the 5-HT3 receptor does not seem to play a major role... a lack of ... |
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|
Source: Wenk, Gary - Departments of Psychology & Neuroscience, Ohio State University |
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Collection: Biology and Medicine |
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| 84 | Is the beneficial antidepressant effect of co-administration of pindolol really due to somatodendritic autoreceptor antagonism? | ||
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Summary: (KD 5-HT=3.8 nM (Peroutka 1986), Ki pindolol =30 nM (Boddeke 1992)). After SSRI administration... The combination of SSRIs with the beta adrenoceptor / 5HT1A receptor antagonist pindolol is currently investigated... autoreceptor antagonist would lead to a more rapid onset of ... |
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|
Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 85 | The role of serotonin in clinical disorders The role of serotonin in clinical disorders | ||
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Summary: adrenoceptors, but also antagonises 5-HT2 and 5-HT3 receptors. Antagonism of these receptors enhances... . Antagonism of the 5-HT2 and 5-HT3 receptors is believed to further concentrate the release of serotonin... treatment with fluoxetine and citalopram on 5-HT ... |
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|
Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of Marine Benthic Ecology and Evolution, |
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Collection: Biology and Medicine ; Environmental Sciences and Ecology |
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| 86 | Rational discovery of novel nuclear hormone receptor antagonists | ||
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Summary: Rational discovery of novel nuclear hormone receptor antagonists Matthieu Schapira* , Bruce M... , with the exception of the human estrogen receptor- , the lack of antagonist-bound ``inactive'' receptor structures... hinders the rational design of re- ceptor antagonists. In this study, we present a strategy for design |
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|
Source: Abagyan, Ruben - School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego |
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|
Collection: Biology and Medicine |
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| 87 | DOI: 10.1126/science.1169243 , 96 (2009);325Science | ||
|
Summary: - brate 5-hydroxytryptamine (serotonin) receptor 3A (5-HT3 receptor) is a serotonin-gated cation chan- nel... the extracellular domain sequences of LGC-40, LGC-53, and LGC-55 with those of MOD-1 and 5-HT3 receptor subunits... channels (10, 13, 29). Cation- selective ... |
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|
Source: Horvitz, H. Robert - Department of Biology, Massachusetts Institute of Technology (MIT) |
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Collection: Biology and Medicine |
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| 88 | Behavioral Neuroscience Copyright 1996by the American Psychological Association, Inc. 1996, VoL 110, No. 4, 809-822 0735-7044/96/$3.00 | ||
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Summary: , 1985; Fleetwood- Walker, Mitchell, Hope, Molony, & Iggo, 1985; Takano & Yaksh, 1992), 5-HT1A and 5-HT3... antagonists (phentolamine or methysergide). Threshold increases generated by serotonin were also partially... .S.Borszcz@Dartmouth.edu. istration of receptor antagonists to ... |
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|
Source: Borszcz, George S. - Department of Psychology, Wayne State University |
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Collection: Biology and Medicine |
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| 89 | TheJournalofGeneralPhysiology J. Gen. Physiol. The Rockefeller University Press $15.00 | ||
|
Summary: , glycine, acetylcholine, and 5-HT3 recep- tors. Cysteine-accessibility studies concluded that the gate... of the 5-HT3A receptor channel. Zn2+ accessibility studies in a chimeric 5-HT3-ACh receptor ... |
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|
Source: Akabas, Myles - Department of Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University |
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|
Collection: Biology and Medicine |
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| 90 | in Burger's Medicinal Chemistry, Vol II Drug Discovery and Drug Development, Chapter 11, pp 357-405. Ed. Abraham, D., | ||
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Summary: or inhibitory synaptic transmission. In mammalian cells, the cation- selective members include nicotinic and 5HT... antagonists are available, a situation that may improve with the characterisation of alpha... 3 receptors, while the anion-selective members include GABAA , GABAC and glycine receptors |
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|
Source: Colquhoun, David - Department of Pharmacology, University College London |
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Collection: Biology and Medicine |
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| 91 | Agonist-, Antagonist-, and Benzodiazepine-Induced Structural Changes in the 1Met113 | ||
|
Summary: -gated ion channel; BZD, benzodiazepine; nACh, nicotinic acetylcholine; 5-HT3, serotonin-type-3; ACh... :483493, 2007 Printed in U.S.A. 483 #12;serotonin-type-3 (5-HT3), GABAC, and glycine receptors. Much is known... regions of the nACh and ... |
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|
Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison |
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Collection: Biology and Medicine |
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| 92 | Following vesicular release, the biogenic amine neurotransmitters dopamine, norepinephrine and serotonin are | ||
|
Summary: of synapses employing 5-HT3 ligand-gated channels) signal through G-protein-coupled Biogenic amine... and trafficking may be influenced by transporter ligands. Recognition that transmitters, antagonists and second... that chronic cocaine treatment modulates DAT antagonist binding and ... |
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|
Source: Blakely, Randy - Department of Pharmacology, Vanderbilt University |
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Collection: Biology and Medicine |
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| 93 | *MRC Laboratory of Molecular Biology, | ||
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Summary: acetylcholine receptor (nAChR) and the serotonin 5-HT3 receptor,which are cationic,and the GABAA (-aminobutyric... of locomotion defective.) Muscle nAChR Neuronal nAChR GABAA glycine GluCl P2X7 5-HT3B MOD-1NMDA AMPA ASICGABAC 5... ... |
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|
Source: Lester, Henry - Division of Biology, California Institute of Technology |
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Collection: Biology and Medicine |
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| 94 | doi: 10.1098/rstb.2005.1788 , 277-2853612006Phil. Trans. R. Soc. B | ||
|
Summary: coevolution Detecting sexual conflict and sexually antagonistic References http... antagonistic coevolution Locke Rowe1,2,* and Troy Day3,4 1 Department of Zoology, University of Toronto... conflict and resultant sexually antagonistic coevolution. We then use published empirical examples |
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Source: Rowe, Locke - Department of Ecology and Evolutionary Biology, University of Toronto |
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Collection: Environmental Sciences and Ecology |
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| 95 | Detecting sexual conflict and sexually antagonistic coevolution | ||
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Summary: Detecting sexual conflict and sexually antagonistic coevolution Locke Rowe1,2,* and Troy Day3,4 1... approaches for detecting interlocus sexual conflict and resultant sexually antagonistic coevolution. We... attributes emerge. First, the dynamics of sexually antagonistic coevolution may obscure the conflict itself |
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|
Source: Day, Troy - Departments of Mathematics and Statistics & Biology, Queen's University (Kingston) |
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Collection: Environmental Sciences and Ecology |
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| 96 | Purinergic Mechanisms Contribute to Mechanosensory Transduction in the Rat Colorectum | ||
|
Summary: afferent fibres by 5-HT(3) receptors. J Physiol 2002;544:861869. 43. Bodin P, Bailey DJ, Burnstock G... attenuated by the selective P2X1, P2X3, and P2X2/3 antagonist 2 ,3 -O-trinitrophenyl- adenosine 5... -triphosphate and by the nonselective P2 antagonists pyridoxyl 5-phosphate ... |
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|
Source: Burnstock, Geoffrey - Autonomic Neuroscience Centre, University College London |
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|
Collection: Biology and Medicine |
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| 97 | Differential Modulation of Clock Speed by the Administration of Intermittent Versus Continuous Cocaine | ||
|
Summary: and tolerance by the co-administration of ondansetron, a 5-HT3 receptor antagonist, and cocaine... , G. R., Joyner, C. M., & Ellinwood, E. H., Jr. (1994). 5-HT3 receptor modulation of behavior during... continuous cocaine administration: Time ... |
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|
Source: Matell, Matthew S. - Department of Psychology, Villanova University |
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Collection: Biology and Medicine |
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| 98 | Neurobiologie und Pharmakotherapie der Alkoholabhngigkeit | ||
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Summary: intake of 50 mg of naltrexone (anticraving drug), n=23 0.50 mg of ondansetron (5HT3 antagonist), n=23 |
|||
|
Source: Durstewitz, Daniel - Research Group Computational Neuroscience, Central Institute of Mental Health, |
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|
Collection: Computer Technologies and Information Sciences ; Biology and Medicine |
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| 99 | nature neuroscience volume 1 no 8 december 1998 659 The neurotoxic actions of glutamate acting at the N-methyl-D- | ||
|
Summary: alpha-adrenergic, 5HT1A, 5HT2, 5HT3 and sigma receptors and calcium chan- nels25,26. The poor... NMDA receptor antagonists13 with chemical structures unlike any of the competitive or uncompetitive... antagonists (Fig. 1a). High-affinity inhibition by ifenprodil depends critically on the ... |
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|
Source: Traynelis, Stephen F. - Department of Pharmacology, Emory University |
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Collection: Biology and Medicine |
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| 100 | Abstract A neutral stimulus can acquire conditioned re-warding properties through association with an intrinsi- | ||
|
Summary: (1997) found that the 5-HT3 antagonist ondansetron during conditioning failed to affect subsequent... - mentation of responding for conditioned reward. On the other hand, systemic administration of the 5-HT3... for conditioned reward by NAc ... |
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|
Source: Beninger, Richard J. - Department of Psychology, Queen's University (Kingston) |
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|
Collection: Biology and Medicine |
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